Publications and communications of Desmet, Christophe

Chen, D., Nemazanyy, I., Peulen, O., Shostak, K., Xu, X., Tang, S. C., Wathieu, C., Turchetto, S., Tielens, S., Nguyen, L., Close, P., Desmet, C., Klein, S., Florin, A., Büttner, R., Petrellis, G., Dewals, B. G., & Chariot, A. (2022). Elp3-mediated codon-dependent translation promotes mTORC2 activation and regulates macrophage polarization. EMBO Journal, 109353. doi:10.15252/embj.2021109353

Wathieu, C., Tielens, S., Lavergne, A., Shostak, K., Rolot, M., El Hachem, N., Xu, X., Close, P., Nguyen, L., Desmet, C., Dewals, B. G.* , & CHARIOT, A.*. (10 May 2022). A role for the tRNA-modifying enzyme Elp3 in tuft cell differentiation and in the immune response in the intestine. Paper presented at Type 2 Immunity in Early Life Symposium, Liège, Belgium.
* These authors have contributed equally to this work.

Van Hulst, G., Jorssen, J., Jacobs, N., Henket, M., Louis, R., Schleich, F., Bureau, F., & Desmet, C. (2022). Anti-IL-5 mepolizumab minimally influences residual blood eosinophils in severe asthma. European Respiratory Journal. doi:10.1183/13993003.00935-2021

Kerselidou, D., Dohai, B. S., Nelson, D. R., Daakour, S., De Cock, N., Hassoun, Z. E. O., Kim, D.-K., Olivet, J., El Assal, D. C., Jaiswal, A., Alzahmi, A., Saha, D., Pain, C., Matthijssens, F., Lemaitre, P., Herfs, M., Chapuis, J., Ghesquiere, B., Vertommen, D., & Twizere, J.-C. (2021). Alternative glycosylation controls endoplasmic reticulum dynamics and tubular extension in mammalian cells. Science Advances, 7 (19). doi:10.1126/sciadv.abe8349

Lemaitre, P., Bai, Q., Legrand, C., Chariot, A., Close, P., Bureau, F., & Desmet, C. (2021). Loss of the Transfer RNA Wobble Uridine-Modifying Enzyme Elp3 Delays T Cell Cycle Entry and Impairs T Follicular Helper Cell Responses through Deregulation of Atf4. Journal of immunology (Baltimore, Md. : 1950). doi:10.4049/jimmunol.2000521

Rapino, F.* , ZHOU, Z.* , RONCERO SANCHEZ, A. M.* , Joiret, M., Seca, C., El Hachem, N., Valenti, G., Latini, S., Shostak, K., Geris, L., Li, P., Huang, G., Mazzucchelli, G., Baiwir, D., Desmet, C., Chariot, A., Georges, M., & Close, P. (2021). Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate. Nature Communications, 12 (1), 2170. doi:10.1038/s41467-021-22254-5
* These authors have contributed equally to this work.

Rosu, A., El Hachem, N., Rapino, F., Rouault-Pierre, K., Jorssen, J., SOMJA, J., Ramery, E., Thiry, M., Nguyen, L., Jacquemyn, M., Daelemans, D., Adams, C. M., Bonnet, D., Chariot, A., Close, P., Bureau, F., & Desmet, C. (2021). Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis. The Journal of experimental medicine, 218 (3). doi:10.1084/jem.20200662

Schurmans, S., Vande Catsyne, C.-A., Desmet, C., & Moes, B. (2021). The phosphoinositide 5-phosphatase INPP5K: from gene structure to in vivo functions. Advances in Biological Regulation. doi:10.1016/j.jbior.2020.100760

Van Hulst, G., Bureau, F., & Desmet, C. (2021). Eosinophils as Drivers of Severe Eosinophilic Asthma: Endotypes or Plasticity? International Journal of Molecular Sciences, 22 (18). doi:10.3390/ijms221810150

Fastrès, A., Pirottin, D., Fievez, L., Tutunaru, A.-C., Bolen, G., Merveille, A.-C., Marichal, T., Desmet, C., Bureau, F., & Clercx, C. (15 December 2020). Identification of pro-fibrotic macrophage populations by single-cell transcriptomic analysis in West Highland white terriers affected with canine idiopathic pulmonary fibrosis. Frontiers in Immunology, 11, 611749. doi:10.3389/fimmu.2020.611749

Fastrès, A., Pirottin, D., Fievez, L., Tutunaru, A.-C., Bolen, G., Merveille, A.-C., Marichal, T., Desmet, C., Bureau, F., & Clercx, C. (20 November 2020). Identification of pro-fibrotic macrophages populations by single-cell transcriptomic analysis in West Highland white terriers affected with canine idiopathic pulmonary fibrosis. Paper presented at 7th FARAH DAY, Liège, Belgium.

Louis, R., Bureau, F., & Desmet, C. (September 2020). Advances toward precision medicine for asthma. Biochemical Pharmacology, 179. doi:10.1016/j.bcp.2020.114081

Fastrès, A., Pirottin, D., Fievez, L., Marichal, T., Desmet, C., Bureau, F., & Clercx, C. (30 July 2020). Characterization of the bronchoalveolar lavage fluid by single cell gene expression analysis in healthy dogs: a promising technique. Frontiers in Immunology, 11, 1707. doi:10.3389/fimmu.2020.01707

Fastrès, A., Pirottin, D., Fievez, L., Marichal, T., Desmet, C., Bureau, F., & Clercx, C. (2020). Characterization of the bronchoalveolar lavage fluid by single cell gene expression analysis in healthy dogs: a promising technique. Journal of Veterinary Internal Medicine, 34 (6). doi:10.1111/jvim.15924

Van Hulst, G., Batugedara, H. M., Jorssen, J., Louis, R., Bureau, F., & Desmet, C. (2020). Eosinophil diversity in asthma. Biochemical Pharmacology, 179. doi:10.1016/j.bcp.2020.113963

Arnone, M., Van Hulst, G., Desmet, C., Bureau, F., Jacobs, N., Gerday, S. (Other coll.), HENKET, M. (Other coll.), & LOUIS, R. (Other coll.). (21 May 2019). Building a comprehensive map of immune cell populations in sputum from patients with eosinophilic asthma. Poster session presented at EDT-Immunology day.

El Abbas, S., Radermecker, C., Bai, Q., BEGUIN, C., Schyns, J., Meunier, M., Pirottin, D., Desmet, C., Meuwis, M.-A., Art, T., Louis, E., Tam, S.-Y., Tsai, M., Bureau, F., Galli, S. J., & Marichal, T. (2019). Epithelial RABGEF1 deficiency promotes intestinal inflammation by dysregulating intrinsic MYD88-dependent innate signaling. Mucosal Immunology. doi:10.1038/s41385-019-0211-z

Farhat, K., Bodart, G., Charlet-Renard, J. D. C., Desmet, C., Moutschen, M., Beguin, Y., Baron, F., Melin, P., Quatresooz, P., Parent, A.-S., Desmecht, D., Sirard, J.-C., Salvatori, R., Martens, H., & Geenen, V. (02 October 2018). Growth hormone (GH) deficient mice with GHRH ablation are severely deficient in vaccine and immune responses against Streptococcus pneumoniae. Frontiers in Immunology, 9, 2175. doi:10.3389/fimmu.2018.02175

Van hede, D., Polese, B., Humblet, C., Wilharm, A., Renoux, V., DORTU, E., de Leval, L., Delvenne, P., Desmet, C., Bureau, F., Vermijlen, D., & Jacobs, N. (June 2018). Human papillomavirus oncoproteins induce a reorganization of epithelial-associated γδ T cells promoting tumor formation. Poster session presented at Gamma delta conferance, Bordeaux, France.

Bakker, J., Balthazart, J., Baron, F., Beguin, Y., Bettendorff, L., Blanpain, C., Bureau, F., Caers, J., Cani, P., Cataldo, D., Cornil, C., Clercx, C., Cloots, R., Colige, A., Daube, G., De Backer, O., de Kerchove d'Exaerde, A., Desmecht, D., Desmet, C., & Wittamer, V. (2018). La souris, le patient, et le faux expert. Décryptage d'une mystification. Le Vif. L'Express.

Farhat, K., Bodart, G., Desmet, C., Moutschen, M., Beguin, Y., Baron, F., Salvatori, R., Martens, H., & Geenen, V. (20 March 2018). GHRH-deleted Mice Are Severely Deficient in Vaccine And Immunological Responses Against Streptococcus Pneumoniae. Paper presented at ENDO 2018, Chicago, United States.

Liégeois, M.* , Legrand, C.* , Desmet, C.* , Marichal, T.* , & Bureau, F.*. (2018). The interstitial macrophage: A long-neglected piece in the puzzle of lung immunity. Cellular Immunology, 330, 91-96. doi:10.1016/j.cellimm.2018.02.001
* These authors have contributed equally to this work.

Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., & Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique.

Farhat, K., Bodart, G., RENARD, J. D. C., Desmet, C., MOUTSCHEN, M., Beguin, Y., Baron, F., Salvatori, R., Geenen, V., & Martens, H. (23 May 2017). A surprising and dramatic neuroendocrine-immune phenotype of mice deficient in Growth Hormone-Releasing Hormone (GHRH). Poster session presented at European Congress of Endocrinology, Lisbonne, Portugal. doi:10.1530/endoabs.49.EP883

Farhat, K., Bodart, G., Renard, C., Desmet, C., MOUTSCHEN, M., BARON, F., Beguin, Y., Salvatori, R., Martens, H., & GEENEN, V. (May 2017). A surprising and dramatic neuroendocrine-immune phenotype of mice deficient in Growth Hormone-Releasing Hormone (GHRH). Poster session presented at The 19th European Congress of Endocrinology, Lisbon, Portugal.

Bureau, F., Marichal, T., Desmet, C., Sabatel, C., Radermecker, C., Fievez, L., & olivier, S. (09 March 2017). Procédés de différenciation in vitro de monocytes en macrophages régulateurs.

Rosu, A., Bai, Q., Ramery, E., Thiry, M., Close, P., Bureau, F., & Desmet, C. (03 February 2017). Loss of transfer RNA U34 modifying enzymes impairs hematopoietic stem and progenitor cell differentiation and function. Poster session presented at Keystone Symposia: Hematopoiesis, Banff, Canada.

Sabatel, C., Radermecker, C., Fievez, L., PAULISSEN, G., Chakarov, S., Fernandes, C., Olivier, S., Toussaint, M., Pirottin, D., Xiao, X., QUATRESOOZ, P., Sirard, J.-C., CATALDO, D., Gillet, L., Bouabe, H., Desmet, C., Ginhoux, F., Marichal, T., & Bureau, F. (01 February 2017). Bacterial CpG-DNA prevents asthma by expanding lung interstitial regulatory macrophages from local and splenic reservoir monocytes. Paper presented at GIGA DAY 2017, Liège, Belgium.

Gallenne, T.* , Ross, K. N.* , Visser, N. L.* , Salony, * , Desmet, C., Wittner, B. S., Wessels, L. F. A., Ramaswamy, S., & Peeper, D. S. (2017). Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer. Oncotarget, 8 (13), 20572-20587. doi:10.18632/oncotarget.16244
* These authors have contributed equally to this work.

Sabatel, C.* , Radermecker, C.* , Fievez, L.* , Paulissen, G., Chakarov, S., Fernandes, C., Olivier, S., Toussaint, M., Pirottin, D., Xiao, X., Quatresooz, P., Sirard, J.-C., Cataldo, D., Gillet, L., Bouabe, H., Desmet, C., Ginhoux, F., Marichal, T.* , & Bureau, F.*. (2017). Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages. Immunity, 46 (3), 457-473. doi:10.1016/j.immuni.2017.02.016
* These authors have contributed equally to this work.

Van hede, D., Polese, B., Humblet, C., Wilharm, A., Renoux, V., Dortu, E., de Leval, L., Delvenne, P., Desmet, C., Bureau, F., Vermijlen, D., & Jacobs, N. (2017). Human papillomavirus oncoproteins induce a reorganization of epithelial-associated gammadelta T cells promoting tumor formation. Proceedings of the National Academy of Sciences of the United States of America, 114 (43), 9056-E9065. doi:10.1073/pnas.1712883114

Farhat, K., Bodart, G., Desmet, C., Moutschen, M., Salvatori, R., Geenen, V., & Martens, H. (07 November 2016). Severe deficiency of the somatotrope GHRH/GH/IGF-1 axis induces a dramatic susceptibility to Streptococcus pneumoniae infection. Poster session presented at Growth Hormone Research Society (GRS) and IGF Society, Tel Aviv, Israel.

Farhat, K., Bodart, G., RENARD, J. D. C., Desmet, C., Moutschen, M., Baron, F., Beguin, Y., Salvatori, R., Geenen, V., & Martens, H. (November 2016). Severe deficiency of the somatotrope GHRH/GH/IGF1 axis induces a dramatic susceptibility to Streptococcus pneumoniae infection. Paper presented at 50e Congrès de la Société Française d'Immunologie (SFI), Paris, France.

Mesnil, C., Raulier, S., Paulissen, G., Xiao, X., Birrell, M., Pirottin, D., Janss, T., Starkl, P., Ramery, E., HENKET, M., SCHLEICH, F., Radermecker, M., Thielemans, K., Gillet, L., Thiry, M., Belvisi, M., LOUIS, R., Desmet, C., Marichal, T., & Bureau, F. (21 October 2016). Lung resident eosinophils represent a distinct cell subset with homeostatic functions. Paper presented at FARAH Day 2016, Liege, Belgium.

Delaunay, S., Rapino, F., Tharun, L., Zhou, Z., Heukamp, L., Termathe, M., Shostak, K., Klevernic, I., Florin, A., Desmecht, H., Desmet, C., Nguyen, L., Leiden, S. A., Willis, A. E., Buettner, R., Chariot, A., & Close, P. (October 2016). ELP3 links tRNA modification to IRES-dependent translation of LEF-1 to promote metastasis in breast cancer. Journal of Experimental Medicine, 213, 2503-2523. doi:10.1084/jem.20160397

Sabatel, C., Radermecker, C., Fievez, L., Paulissen, G., Chakarov, S., Toussaint, M., Desmet, C., Ginhoux, F., Marichal, T., & Bureau, F. (2016). CpG-DNA expand immunosuppressive interstitial macrophages from Ly6c+ local precursors. In Proceeding of Cell Symposia: 100 years of phagocytes.

Janss, T., Mesnil, C., Pirottin, D., Lemaitre, P., Marichal, T., Bureau, F.* , & Desmet, C.*. (2016). Interferon response factor-3 promotes the pro-Th2 activity of mouse myeloid CD11b+ dendritic cells. European Journal of Immunology, 46, 2614-2628.
* These authors have contributed equally to this work.

Janss, T., Mesnil, C., Pirottin, D., Lemaitre, P., Marichal, T., Bureau, F.* , & Desmet, C.*. (2016). Interferon response factor-3 promotes the pro-Th2 activity of mouse lung CD11b+ conventional dendritic cells in response to house dust mite allergens. European Journal of Immunology, 46 (11), 2614-2628. doi:10.1002/eji.201646513
* These authors have contributed equally to this work.

Mesnil, C.* , Raulier, S.* , Paulissen, G., Xiao, X., Birrell, M., Pirottin, D., Janss, T., Starkl, P., Ramery, E., HENKET, M., SCHLEICH, F., Radermecker, C., Thielemans, K., Gillet, L., Thiry, M., Belvisi, M., Louis, R., Desmet, C., Marichal, T.* , & Bureau, F.*. (2016). Lung-resident eosinophils represent a distinct regulatory eosinophil subset. Journal of Clinical Investigation, 126 (9), 3275-3295. doi:10.1172/JCI85664
* These authors have contributed equally to this work.

Raulier, S., Mesnil, C., Paulissen, G., Pirottin, D., Janss, T., Desmet, C., Marichal, T., & Bureau, F. (28 September 2015). Identification of a novel lung-resident eosinophil population with immunomodulatory properties in mice. Paper presented at ERS 2015 international congress, Amsterdam, Netherlands.

Sabatel, C., Radermecker, C., Fievez, L., Paulissen, G., Toussaint, M., Desmet, C., Marichal, T., Bureau, F., & Chakarov, S. (Other coll.). (08 September 2015). A lung-resident Ly6c+ monocyte proliferates to give rise to immunosuppressive lung macrophages. Poster session presented at 4ème European Congress of Immunology, Vienne, Austria.

Frellstedt, L., Gosset, P., Kervoaze, G., Hans, A., Desmet, C., Pirottin, D., Bureau, F., Lekeux, P., & Art, T. (2015). The Innate Immune Response of Equine Bronchial Epithelial Cells is Altered by Training. Veterinary Research, 46 (3), 1-12. doi:10.1186/s13567-014-0126-3

Sabatel, C., Radermecker, C., Chakarov, S., Fievez, L., PAULISSEN, G., Toussaint, M., Desmet, C., Ginhoux, F., Marichal, T., & Bureau, F. (2015). A lung-resident Ly6c+ monocyte proliferates to give rise to immunosuppressive lung macrophages. European Respiratory Journal. Supplement, 46 (59), 5098.

Sabatel, C., Radermecker, C., Fievez, L., Paulissen, G., Chakarov, S., Desmet, C., Ginhoux, F., Toussaint, M., Marichal, T., & Bureau, F. (2015). A lung-resident Ly6c+ monocyte proliferates to give rise to immunosuppressive lung macrophages. Poster session presented at ERS International congress.

Frellstedt, L., Waldschmidt, I., Gosset, P., Desmet, C., Pirottin, D., Bureau, F., Farnir, F., Franck, T., Dupuis-Tricaud, M.-C., Lekeux, P., & Art, T. (2014). Training Modifies Innate Immune Responses in Blood Monocytes and in Pulmonary Alveolar Macrophages. American Journal of Respiratory Cell and Molecular Biology, 51 (1), 135-142. doi:10.1165/rcmb.2013-0341OC

Mesnil, C., Sabatel, C., Marichal, T., Toussaint, M., Cataldo, D., Drion, P., Lekeux, P., Bureau, F., & Desmet, C. (2014). Resident CD11b+CD64-Ly6C-, but not neo-recruited inflammatory CD11b+CD64+Ly6C+ dendritic cells are able to induce allergic airway sensitization to house dust mite antigens. In proceeding of the 13th International Symposium on Dendritic Cells.

Pirottin, D., Schurmans, S., Francois, C., Farnir, F., Closset, R., Bureau, F., & Desmet, C. (2014). Generation and validation of a mouse model for conditional inactivation of PLAGL1. In Proceedings of the 4th edition : FARAH Day 2014.

Desmet, C. (2013). Adjuvants targeting the DNA sensing pathways – Alum based adjuvants. In K. Ishii & C. K. Tang (Eds.), Biological DNA Sensor: The Impact of Nucleic Acids on Diseases and Vaccinology (pp. 271-312). Amsterdam, Netherlands: Elsevier. doi:10.1016/B978-0-12-404732-7.00012-5

Desmet, C., Gallenne, T., Prieur, A., Reyal, F., Visser, N., Wittner, B., Smit, M., Geiger, T., Laoukili, J., Iskit, S., Rodenko, B., Zwart, W., Evers, B., Horlings, H., Ajouaou, A., Zevenhoven, J., van Vliet, M., Ramaswamy, S., Wessels, L., & Peeper, D. S. (2013). Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis. Proceedings of the National Academy of Sciences of the United States of America. doi:10.1073/pnas.1222085110

Crotta, S., Davidson, S., Mahlakoiv, T., Desmet, C., Buckwalter, M., Albert, M., Staeheli, P., & Wack, A. (2013). Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia. PLoS Pathogens. doi:10.1371/journal.ppat.1003773

Frellstedt, L., Gosset, P., Desmet, C., Pirottin, D., Bureau, F., Waldschmidt, I., Dupuis-Tricaud, M.-C., Lekeux, P., & Art, T. (2013). Training modifies the innate immune response both in the airways and in blood in horses. In Proceedings of the ICI. doi:10.3389/conf.fimmu.2013.02.00083

Mesnil, C., Sabatel, C., Marichal, T., Toussaint, M., Cataldo, D., Drion, P., Lekeux, P., Bureau, F., & Desmet, C. (2013). Resident lung CD11b+Ly6C- dendritic cells are responsible for allergic airway sensitization to house dust mite in mice. In Proceeding of International Congress of Immunology 2013.

Mesnil, C., Sabatel, C., Marichal, T., Toussaint, M., Cataldo, D., Drion, P., Lekeux, P., Bureau, F., & Desmet, C. (2013). Resident CD11b+Ly6C-, not neo-recruited inflammatory CD11b+Ly6C+ dendritic cells mediate allergic airway sensitization to house dust mite antigens. In Proceeding of the Abcam symposium on Allergy and Asthma 2013.

Toussaint, M., Fievez, L., Drion, P., Cataldo, D., Bureau, F., Lekeux, P., & Desmet, C. (2013). Myeloid hypoxia-inducible factor 1alpha prevents airway allergy in mice through macrophage-mediated immunoregulation. Mucosal Immunology, 6 (3), 485-97. doi:10.1038/mi.2012.88

Toussaint, M., Fievez, L., Drion, P., Cataldo, D., Bureau, F., Lekeux, P., & Desmet, C. (2013). Myeloid Hif1alpha counteracts allergic airway sensitization in mice through macrophage-mediated immunoregulation. In Abstract book of Keystone Symposium "Myeloid Cells: Regulation and Inflammation".

Menten, C., Faccinetto, C., Golovchenko, M., Dupiereux-Fettweis, I., Van Lerberghe, P.-B., DUBOIS, S., Desmet, C., Elmoualij, B., Baron, F., Rudenko, N., Oury, C., Heinen, E., & Couvreur, B. (December 2012). Neutrophil Extracellular Traps (NET) Entrap and Kill Borrelia burgdorferi sensu stricto Spirochetes and Are not Affected by Ixodes ricinus Tick Saliva. Journal of Immunology, 189 (11), 5393-5401. doi:10.4049/jimmunol.1103771

El Abbas, S., Frellstedt, L., Art, T., Pirottin, D., Tosi, I., Dupuis, M.-C., Lekeux, P., Bureau, F., & Desmet, C. (19 October 2012). Characterization of T-helper lymphocytes in peripheral blood and bronchoalveolar lavage of healthy horses and in horses with recurrent airway obstruction. Poster session presented at Proceedings of the 2nd Scientific Meeting of the Faculty of Veterinary Medicine, Liège, Belgium.

Frellstedt, L., Gosset, P., Desmet, C., Pirottin, D., Bureau, F., Lekeux, P., & Art, T. (19 October 2012). Investigation of the effect of exercise on the innate immunity in horses. Poster session presented at Proceedings of the 2nd Scientific Meeting of the Faculty of Veterinary Medicine, Liège, Belgium.

Peeper, D. S., Desmet, C., & Reyal, F. (06 September 2012). Fra-1 target genes as drug targets for treating cancer.

Mesnil, C., Sabatel, C., Marichal, T., Toussaint, M., Cataldo, D., Drion, P., Lekeux, P., Bureau, F., & Desmet, C. (2012). Resident non inflammatory CD11b+ lung dendritic cells are responsible for allergic airway sensitization to house dust mite in mice. In Proceedings Giga Day 2012.

Toussaint, M., Fievez, L., Drion, P., Cataldo, D., Bureau, F., Lekeux, P., & Desmet, C. (2012). Myeloid Hypoxia‐inducible factor 1α prevents airway allergy in mice through macrophage‐mediated immunoregulation. In Proceedings Giga Day 2012.

Desmet, C., & Ishii, K. J. (2012). Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination. Nature Reviews. Immunology, 12 (7), 479-491. doi:10.1038/nri3247

Marichal, T., Bureau, F., & Desmet, C. (2012). L'ADN du soi, allie du systeme immunitaire pour la fonction adjuvante de l'alun. MS. Medecine Sciences, 28 (1), 31-3. doi:10.1051/medsci/2012281011

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobyiama, K., Lekeux, P., Cevaiyr, C., Akira, S., Ishii, K. J., Bureau, F., & Desmet, C. (2012). Release and Innate detection of host cell DNA mediates the adjuvant effects of aluminum salts on adaptive responses. In Proceedings of the 1St Winter School Immunology.

Mesnil, C., Sabatel, C., Marichal, T., Toussaint, M., Cataldo, D., Drion, P., Lekeux, P., Bureau, F., & Desmet, C. (2012). Resident non inflammatory CD11b+ lung dendritic cells are responsible for allergic airway sensitization to house dust mite in mice. In Proceeding of the J2R.

Mesnil, C.* , Sabatel, C.* , Marichal, T., Toussaint, M., Cataldo, D., Drion, P., Lekeux, P., Bureau, F.* , & Desmet, C.*. (2012). Resident CD11b(+)Ly6C(-) Lung Dendritic Cells Are Responsible for Allergic Airway Sensitization to House Dust Mite in Mice. PLoS ONE, 7 (12), 53242. doi:10.1371/journal.pone.0053242
* These authors have contributed equally to this work.

Toussaint, M., Fievez, L., Desmet, C., Pirottin, D., Farnir, F., Bureau, F., & Lekeux, P. (2012). Increased hypoxia-inducible factor 1alpha expression in lung cells of horses with recurrent airway obstruction. BMC Veterinary Research, 8 (1), 64. doi:10.1186/1746-6148-8-64

Wallemacq, H., Bedoret, D., Pujol, J., Desmet, C., Drion, P., Farnir, F., Mainil, J., Lekeux, P., Bureau, F., & Fievez, L. (2012). CD40 triggering induces strong cytotoxic T lymphocyte responses to heat-killed Staphylococcus aureus immunization in mice: a new vaccine strategy for staphylococcal mastitis. Vaccine, 30 (12), 2116-2124. doi:10.1016/j.vaccine.2012.01.039

Toussaint, M., Fievez, L., Lekeux, P., Bureau, F., & Desmet, C. (2011). Myeloid HIF-1alpha prevents airway allergy in mice by promoting macrophage-mediated immunosuppression. In Proceedings of the 1st Scientific Meeting of the Faculty of Veterinary Medicine (pp. 3). Liège, Belgium: Presses de la Faculté de Médecine Vétérinaire de l'Université de Liège.

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K. J., Bureau, F.* , & Desmet, C.*. (August 2011). DNA released from dying host cells mediates aluminum adjuvant activity. Nature Medicine, 17, 996-1002. doi:10.1038/nm.2403
* These authors have contributed equally to this work.

Marichal, T., Bedoret Denis, Mesnil Claire, Pichavant Murielle, Goriely Stanislas, Goldman Michel, Lekeux, P., Bureau, F., & Desmet, C. (2011). Interferon Response Factor-3 is essential for house dust mite-induced airway allergy. In Proceedings of the Belgian Thoracic Society Annual Meeting.

Marichal, T., Bedoret, D., Mesnil, C., Goriely, S., Goldman, M., Lekeux, P., Bureau, F., & Desmet, C. (2011). IRF3 is essential for house dust mite-induced airway allergy in mice. In Proceedings GIGA-Day 2011.

Marichal, T., Bedoret, D., Mesnil, C., Pichavant, M., Goriely, S., Trottein, F., Cataldo, D., Goldman, M., Lekeux, P., Bureau, F., & Desmet, C. (May 2011). Interferon Response Factor 3 is essential for house dust mite-induced airway allergy. Paper presented at Gaxo Smith Kline Award in Pneumology, Brussels, Belgium.

Frellstedt, L., Gosset, P., Desmet, C., Pirottin, D., Bureau, F., Lekeux, P., & Art, T. (2011). Investigation of the innate immunity in the lower respiratory tract in exercising horses. In Proceedings of the 1st Scientific Meeting of the Faculty of Veterinary Medicine (pp. 2). Liège, Belgium: Presses de la Faculté de Médecine Vétérinaire de l'Université de Liège.

Legutko, A.* , Marichal, T.* , Fievez, L., Bedoret, D., Mayer, A., de Vries, H., Klotz, L., Drion, P., Heirman, C., CATALDO, D., LOUIS, R., Thielemans, K., Andris, F., Leo, O., Lekeux, P., Desmet, C.* , & Bureau, F.*. (2011). Sirtuin 1 Promotes Th2 Responses and Airway Allergy by Repressing Peroxisome Proliferator-Activated Receptor-γ Activity in Dendritic Cells. Journal of Immunology, 187 (9), 4517-4529. doi:10.4049/jimmunol.1101493
* These authors have contributed equally to this work.

Marichal, T., Ohata, K., Bedored, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K., Bureau, F., & Desmet, C. (2011). IRF3-dependent activation of inflammatory dendritic cells by extracellular host DNA mediates the adjuvant activity of alum on TH2 responses. Paper presented at 25th Annual Meeting of the European Macrophage and Dendritic cell Society, Brussels, Belgium.

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K., Bureau, F., & Desmet, C. (2011). Self-DNA release mediates the adjuvant effects of aluminum salts. Poster session presented at Cold Spring Harbor Laboratory Meeting: 4th meeting on Harnessing immunity to prevent and treat disease, New York, United States.

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K., Bureau, F., & Desmet, C. (2011). Self-DNA release mediates the adjuvant effects of aluminium salts. Poster session presented at Cold Spring Harbor Laboratory, New-York, United States.

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K., Bureau, F., & Desmet, C. (2011). Release and innate immune detection of host cell DNA mediate the adjuvant activity of aluminum salts. Paper presented at 4th International Conference on Crossroads between Innate and Adaptive Immunity, Mykonos, Greece.

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K., Bureau, F., & Desmet, C. (2011). Release and innate immune detection of host cell DNA mediate the adjuvant activity of aluminum salts. Poster session presented at 4th International Conference on Crossroads between Innate and Adaptive Immunity, Mykonos, Greece.

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K., Bureau, F., & Desmet, C. (2011). IRF3-dependent activation of inflammatory dendritic cells by extracellular host DNA mediates the adjuvant activity of alum on TH2 responses. Poster session presented at 25th Annual Meeting of the European Macrophage and Dendritic cell Society, Brussels, Belgium.

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobyiama, K., Lekeux, P., Cevayir, C., Akira, S., Ishii, K. J., Bureau, F., & Desmet, C. (2011). Self-DNA release mediates the adjuvant effect of aluminum salts. In Proceedings of the 4th meeting on Harnessing immunity to prevent and treat diseases.

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobyiama, K., Lekeux, P., Cevayir, C., Akira, S., Ishii, K. J., Bureau, F., & Desmet, C. (2011). IRF-3 dependent activation of inflammatory dendritic cells by extracellular host DNA mediates the adjuvant activity of alum on Th2 responses. In Proceedings of the 25th annual meeting of the European Macrophage and Dendritic Cell Society.

Marichal, T., Ohata, K., Mesnil, C., Kobyiama, K., Lekeux, P., Cevaiyr, C., Akira, S., Ishii, K. J., Bureau, F., & Desmet, C. (2011). Release and innate detection of host cell DNA mediates the adjuvant effects of aluminum salts. In Proceedings of te 4th International Conference on Crossroads between Innate and Adaptive Immunity.

Paulissen, G., Rocks, N., Guéders, M., Bedoret, D., Crahay, C., Quesada Calvo, F., Hacha, J., Bekaert, S., Desmet, C., Foidart, J.-M., Bureau, F., Noël, A., & Cataldo, D. (2011). ADAM-8, a metalloproteinase, drives acute allergen-induced airway inflammation. European Journal of Immunology, 41 (2), 380-91. doi:10.1002/eji.200940286

Raulier, S., Bureau, F., Desmet, C., & Pirottin, D. (2011). Etude du rôle des facteurs de transcription c-Maf et MafB dans la différenciation et la fonction des macrophages régulateurs: impact sur l'homéostasie immune mucosale. In Proceedings of the 1st FMV Scientific Meeting.

Marichal, T., Bedoret Denis, Mesnil, C., Goriely Stanislas, Goldman Michel, Lekeux, P., Bureau, F., & Desmet, C. (2010). Interferon Response Factor 3 is required for airway allergy to house dust mite in mice. In Short Book of the Annual Congress of the Euopean Respiratory Society (ERS), Barcelone.

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Kobyiama, K., Lekeux, P., Cevaiyr, C., Akira, S., Ishii, K. J., Bureau, F., & Desmet, C. (February 2010). Release and innate detection of hot cell DNA mediates the adjuvant effects of aluminium salts on adaptive responses. Paper presented at First winter school on Advanced Immunology, Awaji Yumebutai International conference center, Japan.

Bedoret, D., Bureau, F., & Desmet, C. (2010). Les macrophages interstitiels, gardiens de l'homeostasie immune pulmonaire. MS. Medecine Sciences, 26 (3), 229-31. doi:10.1051/medsci/2010263229

Marichal, T., Bedoret, D., Mesnil, C., Pichavant, M., Goriely, S., Trottein, F., Cataldo, D., Goldman, M., Lekeux, P., Bureau, F.* , & Desmet, C.*. (2010). Interferon Response Factor 3 is essential for house dust mite-induced airway allergy. Journal of Allergy and Clinical Immunology, 126 (4), 836-844. doi:10.1016/j.jaci.2010.06.009
* These authors have contributed equally to this work.

Warzée, B., Mesnil, C., Hober, D., Caloone, D., Pirottin, D., Garigliany, M.-M., Desmecht, D., Drion, P., Journot, L., Lekeux, P., Bureau, F.* , & Desmet, C.*. (2010). Viral induction of Zac1b through TLR3- and IRF3-dependent pathways. Molecular Immunology, 48 (1-3), 119-127. doi:10.1016/j.molimm.2010.09.004
* These authors have contributed equally to this work.

Bedoret, D., Wallemacq, H., Marichal, T., Desmet, C., Quesada Calvo, F., Henry, E., Closset, R., Dewals, B. G., Thielen, C., Gustin, P., de Leval, L., Van Rooijen, N., Le Moine, A., Vanderplasschen, A., Cataldo, D., Drion, P., Moser, M., Lekeux, P., & Bureau, F. (2009). Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice. Journal of Clinical Investigation, 119 (12), 3723-38. doi:10.1172/JCI39717

Marichal, T., Bedoret, D., Goriely, M., Goldman, M., Lekeux, P., Bureau, F., & Desmet, C. (2009). IRF3 is required for the induction of allergic airway inflammation by lung dendritic cells in a mouse model of house dust mite-induced atopic asthma. In Abstracts of the 17th Annual European Respiratory Society Congress, Vienna, Austria.

Marichal, T., Bedoret, D., Goriely, M., Goldman, M., Lekeux, P., Bureau, F., & Desmet, C. (2009). IRF3 is required for induction of allergic airway inflammation by dendritic cells. Paper presented at Abcam Allergy and Asthma Symposium, Bruges, Belgium.

Marichal, T., Bedoret, D., Goriely, S., Goldman, M., Lekeux, P., Bureau, F., & Desmet, C. (2009). IRF3 is required for induction of allergic airway inflammation by dendritic cells. Poster session presented at Abcam Allergy and Asthma Symposium, Bruges, Belgium.

Peeper, D. S., Desmet, C., & Reyal, F. (17 March 2008). Markers providing prognosis of metastasis among cancer patients.

Desmet, C., Prieur, A., Reyal, F., Geiger, T., Smit, M., Horlings, H., Ajouaou, A., Meuleman, W., Van Vliet, M., Zevenhoven, J., Wessels, L., & Peeper, D. S. (2008). Fra-1 and its associated transcriptome are central determinants of human breast cancer metastasis. Poster session presented at AACR Conference on Metastasis, Vancouver, Canada.

Henry, E., Desmet, C., Garze, V., Fievez, L., Bedoret, D., Heirman, C., Faisca, P., Jaspar, F., Gosset, P., Jacquet, A., Desmecht, D., Thielemans, K., Lekeux, P., Moser, M., & Bureau, F. (2008). Dendritic cells genetically engineered to express IL-10 induce long-lasting antigen-specific tolerance in experimental asthma. Journal of Immunology, 181 (10), 7230-7242. doi:10.4049/jimmunol.181.10.7230

Kuilman, T., Michaloglou, C., Vredeveld, L. C. W., Douma, S., van Doorn, R., Desmet, C., Aarden, L. A., Mooi, W. J., & Peeper, D. S. (2008). Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell, 133 (6), 1019-1031. doi:10.1016/j.cell.2008.03.039

Fievez, L., Desmet, C., Henry, E., Pajak, B., Hegenbarth, S., Garzé, V., Bex, F., Jaspar, F., Boutet, P., Gillet, L., Vanderplasschen, A., Knolle, P. A., Leo, O., Moser, M., Lekeux, P., & Bureau, F. (2007). STAT5 is an Ambivalent Regulator of Neutrophil Homeostasis. Poster session presented at 11ème BIOFORUM de Liège, Liège, Belgium.

Fievez, L., Desmet, C., Henry, E., Pajak, B., Hegenbarth, S., Garze, V., Bex, F., Jaspar, F., Boutet, P., Gillet, L., Vanderplasschen, A., Knolle, P. A., Leo, O., Moser, M., Lekeux, P., & Bureau, F. (2007). Stat5 Is an Ambivalent Regulator of Neutrophil Homeostasis. PLoS ONE, 2 (1), 727. doi:10.1371/journal.pone.0000727

Henry, E., Desmet, C., Garzé, V., Fievez, L., Bedoret, D., Heirman, C., Faisca, P., Jaspar, F. J., Gosset, P., Jacquet, A. P. A., Desmecht, D., Lekeux, P., Moser, M., & Bureau, F. (2007). Dendritic cells genetically engineered to express IL-10 induce long-lasting antigen-specific tolerance in experimental asthma. Poster session presented at 11ème BIOFORUM de Liège, Liège, Belgium.

Seumois, G., Fillet, M., Gillet, L., Faccinetto, C., Desmet, C., Francois, C., Dewals, B. G., Oury, C., Vanderplasschen, A., Lekeux, P., & Bureau, F. (2007). De novo C16- and C24-ceramide generation contributes to spontaneous neutrophil apoptosis. Journal of Leukocyte Biology, 81 (6), 1477-1486. doi:10.1189/jlb.0806529

Desmet, C. (2006). Nuclear Factor-kappa B and Activator Protein-1: roles and potential as therapeutic targets in asthmatic inflammation. Annales de Médecine Vétérinaire, 150 S, 19-22.

Desmet, C., & Peeper, D. S. (2006). The neurotrophic receptor TrkB: a drug target in anti-cancer therapy ? Cellular and Molecular Life Sciences, 63 (7-8), 755-759. doi:10.1007/s00018-005-5490-8

Desmet, C. (2005). Le Facteur Nucléaire-kappaB et la Protéine Activatrice-1 : Roles et potentiel en tant que cibles thérapeutiques dans l'inflammation asthmatique. Unpublished doctoral thesis, ULiège - Université de Liège.
Jury: Lekeux, P. (Promotor).

Desmet, C., Gosset, P., Garzé, V., Pajak, B., Fievez, L., Lekeux, P., & Bureau, F. (2005). Selective inhibition of AP-1 activity in airway immune cells ameliorates experimental asthma. In Proceedings: The American Thoracic Society (pp. 737).

Desmet, C., Gosset, P., Henry, E., Garze, V., Faisca, P., Vos, N., Jaspar, F., Burin Kefer, D., Lambrecht, B., Desmecht, D., Pajak, B., Moser, M., Lekeux, P., & Bureau, F. (2005). Treatment of experimental asthma by decoy-mediated local inhibition of activator protein-1. American Journal of Respiratory and Critical Care Medicine, 172 (6), 671-678. doi:10.1164/rccm.200410-1431OC

Desmet, C., Gosset, P., Pajak, B., Garzé, V., Lekeux, P., & Bureau, F. (2005). Selective decoy-mediated inhibition of activator protein-1 activity in the airways pevents experimental asthmatic inflammation. European Respiratory Journal, 26, 233.

Desmet, C., Louis, R., Lekeux, P., & Bureau, F. (2005). Le controle de la transcription genique en tant que nouvelle cible therapeutique dans le traitement de l'asthme. Revue Médicale de Liège, 60 (10), 789-795.

Desmet, C., Warzée, B., Gosset, P., Melotte, D., Rongvaux, A., Gillet, L., Fievez, L., Seumois, G., Vanderplasschen, A., Staels, B., Lekeux, P., & Bureau, F. (2005). Pro-inflammatory properties for thiazolidinediones. Biochemical Pharmacology, 69 (2), 255-265. doi:10.1016/j.bcp.2004.09.017

Fievez, L., Desmet, C., Seumois, G., Vanderplasschen, A., Lekeux, P., & Bureau, F. (2005). STAT5 promotes granulocyte survival during inflammation. American Journal of Respiratory and Critical Care Medicine, 171, 325.

Fievez, L., Kirschvink, N., Onclinx, C., Belleflamme, M., Desmet, C., Peck, M., & Gustin, P. (2005). Protection by theophylline of inflammation and emphysema induced by repeated inhalation of cadmium chloride in rats. American Journal of Respiratory and Critical Care Medicine, 171, 93.

Kirschvink, N., Fievez, L., Desmet, C., Peck, M., Smith, N., Marlin, D., & Gustin, P. (2005). Theophylline increases glutathione in BAL of cadmium-exposed rats. In Proceedings of the American Thoracic Society, San Diego, California (pp. 750).

Kirschvink, N., Leemans, J., Delvaux, F., Clercx, C., Fievez, L., Desmet, C., & Gustin, P. (2005). Repeatability of allergen challenges in a feline model of asthma : effect on airway reactivity and airway inflammation. In Proceedings of the American Thoracic Society, San Diego, California (pp. 780).

Art, T., Desmet, C., Lekeux, P., De Moffarts, B., Couetil, L., Becker, M., Franck, T., Kohnen, S., Deby-Dupont, G., & Serteyn, D. (2004). Myeloperoxydase concentration in bronchoalveolar lavage from healthy and heavy horses. In Proceedings : 22nd Symposium of the Veterinary and Comparative Respiratory Society (pp. 74-75).

Desmet, C., Gosset, P., Pajak, B., Cataldo, D., Bentires-Alj, M., Lekeux, P., & Bureau, F. (2004). Selective blockade of NF-kB activity in airway immune cells inhibits the effector phase of experimental asthma. Paper presented at 22nd Symposium of the Veterinary and Comparative Respiratory Society, Montreal, Canada.

Desmet, C., Gosset, P., Pajak, B., Cataldo, D., Bentires-Alj, M., Lekeux, P., & Bureau, F. (2004). Selective blockade of NF-kappaB activity in airway immune cells inhibits the effector phase of experimental asthma. Poster session presented at 22nd Symposium of the Veterinary and Comparative Respiratory Society, Montréal, Canada.

Desmet, C., Gosset, P., Pajak, B., Cataldo, D., Bentires-Alj, M., Lekeux, P., & Bureau, F. (2004). Selective blockade of NF-kappa B activity in airway immune cells inhibits the effector phase of experimental asthma. Journal of Immunology, 173 (9), 5766-5775. doi:10.4049/jimmunol.173.9.5766

Desmet, C., Warsée, B., Mélotte, D., Rongvau, A., Vanderplasschen, A., Lekeux, P., & Bureau, F. (2004). Effects of thiazolidinediones on tumor necrosis factor R alpha induced inflammatory cytokine expression. Pflügers Archiv: European Journal of Physiology, 447, 8-23.

Fievez, L., Desmet, C., Pajak, B., Gillet, L., Vanderplasschen, A., Lekeux, P., & Bureau, F. (2004). STAT5 promotes granulocyte survival during inflammation. Pflügers Archiv: European Journal of Physiology, 447, 8-24.

Fievez, L., Desmet, C., Seumois, G., Pajak, B., Gillet, L., Vanderplasschen, A., Lekeux, P., & Bureau, F. (2004). STAT5 promotes granulocyte survival during lung inflammation. In Proceedings: 22nd Symposium of the Veterinary and Comparative Respiratory Society (pp. 69). Veterinary and Comparative Respiratory Society.

Vincke G., Kirschvinck, N., Fievez, L., Desmet, C., & Gustin, P. (2004). Repeated cadmium nebulization induces MMP-2 and MMP-9 activation in bronchoalveolar lavage fluid of rats. In Repeated cadmium nebulization induces MMP-2 and MMP-9 activation in bronchoalveolar lavage fluid of rats. Veterinary and Comparative respiratory Society.

Desmet, C., Warzée, B., Mélotte, D., Rongvaux, A., Vanderplasschen, A., Lekeux, P., & Bureau, F. (2003). Effects of thiazolidinediones on tumor necrosis factor-α-induced inflammatory cytokine expression. Poster session presented at Autumn Meeting of the Belgian Society of Fundamental and Clinical Physiology and Pharmacology, Liège, Belgium.

Fievez, L., Desmet, C., Pajak, B., Gillet, L., Vanderplasschen, A., Lekeux, P., & Bureau, F. (2003). STAT5 promotes granulocyte survival during inflammation. Poster session presented at Autumn Meeting of the Belgian Society of Fundamental and Clinical Physiology and Pharmacology, Liège, Belgium.

Bureau, F.* , Desmet, C.* , Burin Kefer, D., Jaspar, F., VolantI, C., Vanderplasschen, A., Pastoret, P.-P., PiettE, J., & Lekeux, P. (May 2002). A proinflammatory role for the cyclopentenone prostaglandins at low micromolar concentrations: Oxidative stress-induced extracellular signal-regulated kinase activation without NF-kappa B inhibition. Journal of Immunology, 168 (10), 5318-5325. doi:10.4049/jimmunol.168.10.5318
* These authors have contributed equally to this work.

Bureau, F., Desmet, C., Mélotte, C., Jaspar, F., Volanti, C., Vanderplasschen, A., Pastoret, P.-P., Piette, J., & Lekeux, P. (2002). Cyclopentenone prostaglandins at low concetrations exert pro-inflammatory effects through oxidative stress-induced ERK1/2 activation. In Proceedings: Spring Meeting of the Belgian Society of Physiology and Pharmacology.

Bureau, F., Desmet, C., Melotte, D., Jaspar, F., Volanti, C., Vanderplasschen, A., Pastoret, P.-P., Piette, J., & Lekeux, P. (2002). A pro-inflammatory role for the cyclopentenone prostaglandins at low concentrations: oxidative stress-induced Erk activation without NF-kB inhibition. Poster session presented at Cell Signaling, Transcription and Translation as Therapeutic Targets Meeting, Luxembourg.

Bureau, F., Desmet, C., Melotte, D., Jaspar, V., Volanti, C., Vanderplasschen, A., Piette, J., & Lekeux, P. (2002). A pro-inflammatory role for the cyclopentenone prostaglandins at low concentrations: oxidative stress-induced ERK activation without NFKB inhibition. In Proceedings : Congress "Cell signaling, transcription and translation as therapeutics targets" (pp. 75).

Bureau, F., Gosset, P., Desmet, C., Bentires-Alj, M., Cataldo, D., Desmecht, D., Vanderplasschen, A., Tonnel, A. B., & Lekeux, P. (2002). Local administration of nuclear factor-kB decoy oligodeoxinucleotides prevents allergic airway inflammation. In 12th European Respiratory Society Annual Congress (pp. 170).

Desmet, C., Bureau, F., & Lekeux, P. (2002). Nuclear factor-kB activity in human and animal models of inflammation : the case of asthma. Paper presented at COST action B20 and COST action 844 joint meeting, Gand, Belgium.

Desmet, C. (September 2001). NF-κB-dependent cytokine production is abolished by cyclopentenone prostaglandins in lung epithelial cells. Paper presented at European Respiratory Symposium, Berlin, Germany.

Bureau, F., Seumois, G., Jaspar, F., Desmet, C., Louis, K., & Lekeux, P. (2001). Expression of c-inhibitor of apoptosis protein-2 in the sputum from asthmatic patients. In Proceedings : 11th European Respiratory Society Annual Congress, Eur. Respir. J., 2001, 18 (Suppl. 33) (pp. 531).

Desmet, C., Fievez, L., Lekeux, P., & Bureau, F. (2001). Cyclopenone prostaglandins inhibit NF-κB activity and inflammatory gene expression in lung epithelial cells. In World Equine Airways Symposium (pp. 61). World Equine Airways Symposium editor.

Desmet, C., Fievez, L., LOUIS, R., Lekeux, P., & Bureau, F. (2001). NF-kappaB-dependent cytokine production is abolished by cyclopentenone prostaglandins in lung epithelial cells. European Respiratory Journal. Supplement, 18, 354.