Publications and communications of Bernard Lakaye

Burniat, A., Noël, A., Colige, A., Vanderplasschen, A., de Kerchove d'Exaerde, A., Kupper Cardozo, A., Van Keymeulen, A., Moens, A., Bondue, A., Herpain, A., Marchant, A., Loumaye, A., Beck, B., Van den Heyden, B., Corvilain, B., Lakaye, B., Rogister, B., Malgrange, B., Michiels, C., ... Brunko, E. (2023). Cent scientifiques répliquent à SEA (Suppression des Expériences sur l’Animal vivant) et dénoncent sa désinformation. La Libre Belgique.

Seutin, V., WANG, F.-C., Lakaye, B., & Hansen, I. (17 December 2022). Les syndromes myasthéniques et myotoniques congénitaux: rencontre des sciences fondamentales et des sciences cliniques [Paper presentation]. Datablitz du service de neurologie du CHU de Liège, Liège, Belgium.

Jehasse, K., Massotte, L., Hartmann, S., Vitello, R., Ringlet, S., Vitello, M., Chua, H. C., Pless, S., Engel, D., Liégeois, J.-F., Lakaye, B., Roeper, J., & Seutin, V. (01 October 2021). The gating pore blocker 1-(2,4-xylyl)guanidinium selectively inhibits pacemaking of midbrain dopaminergic neurons. Neuropharmacology, 197, 1-15. doi:10.1016/j.neuropharm.2021.108722

Jehasse, K., Jacquerie, K., de Froidmont, A., Lemoine, C., Grisar, T., Stouffs, K., Lakaye, B., & Seutin, V. (2021). Functional analysis of the F337C mutation in the CLCN1 gene associated with dominant myotonia congenita reveals an alteration of the macroscopic conductance and voltage dependence. Molecular Genetics and Genomic Medicine, 1588. doi:10.1002/mgg3.1588

Jehasse, K., Massotte, L., Hartmann, S., Vitello, R., Ringlet, S., Lakaye, B., Liégeois, J.-F., Roeper, J., & Seutin, V. (22 May 2020). On the path to understanding pacemaking of dopaminergic neurons [Poster presentation]. Virtual Dopamine Meeting.

Sambon, M., Gorlova, A., Demelenne, A., Alhama-Riba, J., Coumans, B., Lakaye, B., Wins, P., Fillet, M., Anthony, D. C., Strekalova, T., & Bettendorff, L. (2020). Dibenzoylthiamine has powerful antioxidant and anti-inflammatory properties in cultured cells and in mouse models of stress and neurodegeneration. Biomedicines, 8, 361. doi:10.3390/biomedicines8090361

Gilsoul, M., Grisar, T., Delgado-Escueta, A. V., de Nijs, L., & Lakaye, B. (27 September 2019). Subtle brain developmental abnormalities in the pathogenesis of juvenile myoclonic epilepsy. Frontiers in Cellular Neuroscience, 13, 433. doi:10.3389/fncel.2019.00433

Gilsoul, M., Medard, L., Coumans, B., Delgado-Escueta, A., de Nijs, L., & Lakaye, B. (July 2018). EFHC1, a protein mutated in Juvenile Myoclonic Epilepsy, interacts with TTLL6 and modulates the level of tubulin polyglutamylation [Poster presentation]. FENS - 11th edition, Berlin, Germany.

Bakker, J., Balthazart, J., Baron, F., Beguin, Y., Bettendorff, L., Blanpain, C., Bureau, F., Caers, J., Cani, P., Cataldo, D., Cornil, C., Clercx, C., Cloots, R., Colige, A., Daube, G., De Backer, O., de Kerchove d'Exaerde, A., Desmecht, D., Desmet, C., ... Wittamer, V. (2018). La souris, le patient, et le faux expert. Décryptage d'une mystification. Le Vif. L'Express.

bailey, J., de Nijs, L., Bai, D., Suzuki, T., Miyamoto, H., Tanaka, M., Patterson, C., Lin, Y.-C., Medina, M., Alonso, M., Serratosa, J., Duron, R., Nguyen, V., Wight, J., Martinez-Juarez, I., Ochoa, A., Jara-Prado, A., Guilhoto, L., Molina, Y., ... Delgado-Escueta*. (March 2018). Variant intestinal-cell kinase in juvenile myoclonic epilepsy. New England Journal of Medicine, 378, 1018-28. doi:10.1056/NEJMoa1700175

Nganou, G., Gomes Da Silva, C., Gladwyn-Ng, I., Engel, D., Coumans, B., Delgado-Escueta, A. V., Tanaka, M., Nguyen, L., Grisar, T., de Nijs, L., & Lakaye, B. (2018). Importin-8 Modulates Division of Apical Progenitors, Dendritogenesis and Tangential Migration During Development of Mouse Cortex. Frontiers in Molecular Neuroscience, 11, 234. doi:10.3389/fnmol.2018.00234

Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., ... Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique.

Nganou, G., Tanaka, M., Coumans, B. (Other coll.), Gomes Da Silva, C. (Other coll.), Grisar, T. (Other coll.), De Nijs, L. (Other coll.), Delgado Escueta, A. V. (Other coll.), & Lakaye, B. (Other coll.). (27 April 2017). Importin-8 could cause CAE/JME by delaying early neuroblast migration [Poster presentation]. 2nd Joint SFBD/SBCF Meeting : When Development meets Cell Biology, Lyon, France.

Bailey, J.* , Patterson, C.* , de Nijs, L., Duron, R., Ngyen, V., Tanaka, M., Medina, M., Jara-Prado, A., Martinez-Juarez, I., Ochoa, A., Molina, Y., Suzuki, T., Alonso, M., Wight, J., Lin, Y., Guilhoto, L., Yacubian, E., Machado-Salas, J., Daga, A., ... Delgado-Escueta, A. (2017). EFHC1 variants in juvenile myoclonic epilepsy: reanalysis according to NHGRI and ACMG guidelines for assigning disease causality. Genetics in Medicine, 19, 144-156. doi:10.1038/gim.2016.86

Vignisse, J., Sambon, M., Gorlova, A., Pavlov, D., Caron, N., Malgrange, B., Shevtsova, E., Svistunov, A., Anthony, D. C., Markova, N., Bazhenova, N., Coumans, B., Lakaye, B., Wins, P., Strekalova, T., & Bettendorff, L. (2017). Thiamine and benfotiamine prevent stress-induced suppression of hippocampal neurogenesis in mice exposed to predation without affecting brain thiamine diphosphate levels. Molecular and Cellular Neuroscience, 82, 126-136. doi:10.1016/j.mcn.2017.05.005

Nganou, G., Coumans, B., De Nijs, L., & Lakaye, B. (06 December 2016). Implication of Importin-8 in mouse brain development [Poster presentation]. American Society for Cell Biology, San Francisco, United States.

Nganou, G., Tanaka, M., Coumans, B., GRISAR, T., De Nijs, L., Delgado-Escueta, A., & Lakaye, B. (December 2016). Importin-8 mutations could cause Jeavons Syndrome, CAE and JME by altering early neuroblast migration [Poster presentation]. American Epilepsy Society, Houston (TEXAS), United States.

Nganou, G., Denijs, L., Lakaye, B., & Coumans, B. (Other coll.). (08 October 2016). Implication of Importin-8 in mouse brain development [Poster presentation]. 6th Belgian Brain Congress, Mons, Belgium. doi:10.3389/conf.fnagi.2016.03.00037

Medard, L., Coumans, B., Lakaye, B., De Nijs, L., & Godin, J. (Other coll.). (June 2016). Myoclonin-1 modulates the post-translational modification of microtubules [Poster presentation]. EMBO | EMBL Symposium: Microtubules: From Atoms to Complex Systems, Heidelberg, Germany.

Medard, L., Godin, J. (Other coll.), Coumans, B. (Other coll.), GRISAR, T. (Other coll.), Delgado-Escueta, A. (Other coll.), Lakaye, B. (Other coll.), & de Nijs, L. (Other coll.). (December 2015). EFHC1/Myoclonin-1 modulates the post-translational modification of microtubules [Poster presentation]. 69th Annual Meeting American Epilepsy Society, Philadelphie, United States.

Medard, L., Lakaye, B., Godin, J. (Other coll.), Coumans, B. (Other coll.), & de Nijs, L. (Other coll.). (2015). Myoclonin 1 modulates the post-translational modification of microtubules [Poster presentation]. BSCDB SPRING MEETING 2015, Liège, Belgium.

Bettendorff, L., Lakaye, B., Kohn, G., & Wins, P. (25 May 2014). In search of a physiological role for thiamine triphosphate and the 25-kDa thiamine triphosphatase [Paper presentation]. 8th International Conference on Thiamine: From Catalysis to Pathology, Liège, Belgium.

Kohn, G., Ectors, F., Lakaye, B., & Bettendorff, L. (May 2014). 25KDa-Thiamine triphosphatase is essential for spermatozoid development in mice [Poster presentation]. 8th International Conference on Thiamine: From Catalysis to Pathology, Liège, Belgium.

Geuzaine, A., Tyhon, A., Grisar, T., Brabant, C., Lakaye, B.* , & Tirelli, E.*. (2014). Amphetamine reward in food restricted mice lacking the melanin-concentrating hormone receptor-1. Behavioural Brain Research, 262, 14-20. doi:10.1016/j.bbr.2013.12.052

Conductier, G., Brau, F., Viola, A., Langlet, F., Ramkumar, N., Dehouck, B., Lemaire, T., Chapot, R., Lucas, L., Rovère, C., Maître, P., Hosseiny, S., Petit-Paitel, A., Adamantidis, A., Lakaye, B., Risold, P., Prevot, V., Meste, O., Nahon, J., & Guyon, A. (2013). Melanin-concentrating hormone regulates beat frequency of ependymal cilia and ventricular volume. Nature Neuroscience, 16, 845-847. doi:10.1038/nn.3401

de Nijs, L., Wolkoff, N., Grisar, T., & Lakaye, B. (2013). Juvenile myoclonic epilepsy as a possible neurodevelopmental disease: role of EFHC1 or Myoclonin 1. Epilepsy and Behavior, 28, 58-S60.

Delvaux, D., Kerff, F., Murty, M. R. V. S., Lakaye, B., Czerniecki, J., Kohn, G., Wins, P., Herman, R., Gabelica, V., Heuze, F., Tordoir, X., Marée, R., Matagne, A., Charlier, P., De Pauw, E., & Bettendorff, L. (2013). Structural Determinants of Specificity and Catalytic Mechanism in mammalian 25-kDa Thiamine Triphosphatase. Biochimica et Biophysica Acta - General Subjects, 1830, 4513-4523. doi:10.1016/j.bbagen.2013.05.014

Gigliobianco, T., GANGOLF, M., Lakaye, B., Pirson, B., von Ballmoos, C., Wins, P., & Bettendorff, L. (January 2013). An alternative role of FoF1-ATP synthase in Escherichia coli: synthesis of thiamine triphosphate. Scientific Reports, 3 (1071). doi:10.1038/srep01071

Kohn, G., Delvaux, D., Lakaye, B., Servais, A.-C., Scholer, G., Fillet, M., Elias, B., Derochette, J.-M., Crommen, J., Wins, P., & Bettendorff, L. (12 September 2012). High inorganic triphosphatase activities in bacteria and mammalian cells: Identification of the enzymes involved. PLoS ONE, 7 (9), 43879. doi:10.1371/journal.pone.0043879

Bettendorff, L., Delvaux, D., Kohn, G., Wins, P., & Lakaye, B. (2012). Molecular evolution of the CYTH superfamily of proteins [Poster presentation]. 22nd IUBMB & 37th FEBS Congress, Seville, Spain, September 4-9, 2012, Sevilla, Spain.

de Nijs, L., Wolkoff, N., Coumans, B., Delgado-Escueta, A., Grisar, T., & Lakaye, B. (2012). Mutations of EFHC1, linked to juvenile myoclonic epilepsy, disrupt radial and tangential migrations during brain development. Human Molecular Genetics, 21 (23), 5106-17. doi:10.1093/hmg/dds356

Grisar, T., Lakaye, B., de Nijs, L., LoTurco, J., Daga, A., & Delgado-Escueta, A. (2012). Myoclonin1/EFHC1 in cell division, neuroblast migration, synapse/dendrite formation in juvenile myoclonic epilepsy. In J. Noebels, M. Avoli, M. Rogawski, R. Olsen, ... A. Delgado-Escueta (Eds.), Jasper's Basic Mechanisms of the Epilepsies, 4th edition (National Center for Biotechnology Information, pp. 1-19). Bethesda (MD), United States: NCBI.

Sherwood, A., Wosiki-Kuhn, M., Nguyen, T., Holland, P., Lakaye, B., Adamantidis, A., & Johnson, A. (2012). The role of melanin-concentrating hormone in conditioned reward learning. European Journal of Neuroscience, 36, 3126-33. doi:10.1111/j.1460-9568.2012.08207.x

Delvaux, D., Murty, M. R. V. S., Gabelica, V., Lakaye, B., Lunin, V. V., Skarina, T., Onopriyenko, O., Kohn, G., Wins, P., De Pauw, E., & Bettendorff, L. (2011). A specific inorganic triphosphatase from Nitrosomonas europaea: structure and catalytic mechanism. Journal of Biological Chemistry, 286, 34023-34035. doi:10.1074/jbc.M111.233585

Gangolf, M., Czerniecki, J., Radermecker, M., Detry, O., NISOLLE, M., JOUAN, C., Martin, D., Chantraine, F., Lakaye, B., Wins, P., Grisar, T., & Bettendorff, L. (October 2010). Thiamine Status in Humans and Content of Phosphorylated Thiamine Derivatives in Biopsies and Cultured Cells. PLoS ONE, 5 (10), 13616. doi:10.1371/journal.pone.0013616

Gigliobianco, T., Lakaye, B., Wins, P., Elmoualij, B., Zorzi, W., & Bettendorff, L. (May 2010). Adenosine thiamine triphosphate accumulates in Escherichia coli cells in response to specific conditions of metabolic stress. BMC Microbiology, 10, 148. doi:10.1186/1471-2180-10-148

Didone, V., Tirelli, E., Quertemont, E., & Lakaye, B. (2010). Ethanol-induced behaviors in mice genetically deficient in MCH1 receptors. Alcoholism, Clinical and Experimental Research, 34 (8), 93A-93.

Leon, C., de Nijs, L., Chanas, G., Delgado-Escueta, A. V., Grisar, T., & Lakaye, B. (2010). Distribution of EFHC1 or myoclonin 1 in mouse neural structures. Epilepsy Research, 88, 196-207. doi:10.1016/j.eplepsyres.2009.11.009

Pachoud, B., Adamantidis, A., Ravassard, P., Luppi, P.-H., Grisar, T., Lakaye, B., & Salin, P.-A. (2010). Major impairments of glutamatergic transmission and long term synaptic plasticity in the hippocampus of mice lacking the melanin-concentrating hormone receptor-1. Journal of Neurophysiology, 104, 1417-1425. doi:10.1152/jn.01052.2009

Wortge, S., Eshkind, L., Cabezas-Wallscheid, N., Lakaye, B., Kim, J., Heck, R., Abassi, Y., Diken, M., Sprengel, R., & Bockamp, E. (2010). Tetracycline-controlled transgene activation using the ROSA26-iM2-GFP knock-in mouse strain permits GFP monitoring of DOX-regulated transgene-expression. BMC Developmental Biology, 10, 95. doi:10.1186/1471-213X-10-95

Brabant, C., Alleva, L., Grisar, T., Quertemont, E., Lakaye, B., Ohtsu, H., Lin, J.-S., Jatlow, P., Picciotto, M. R., & Tirelli, E. (2009). Effects of the H(3) receptor inverse agonist thioperamide on cocaine-induced locomotion in mice: role of the histaminergic system and potential pharmacokinetic interactions. Psychopharmacology, 202 (4), 673-87. doi:10.1007/s00213-008-1345-y

de Nijs, L., Leon, C., Nguyen, L., LoTurco, J. J., Delgado-Escueta, A. V., Grisar, T., & Lakaye, B. (2009). EFHC1 interacts with microtubules to regulate cell division and cortical development. Nature Neuroscience, 12 (10), 1266-74. doi:10.1038/nn.2390

Lakaye, B., Coumans, B., Harray, S., & Grisar, T. (2009). Melanin-concentrating hormone and immune function. Peptides, 30, 2076-80. doi:10.1016/j.peptides.2009.05.004

Lakaye, B., de Nijs, L., Leon, C., & Grisar, T. (2009). Cytoskeletal genes and idiopathic epilepsies. In A. Schwartzkroin (Ed.), Encyclopedia of Basic Epilepsy Research (pp. 323-329). Oxford Academic Press.

Adamantidis, A., Salvert, D., Goutagny, R., Lakaye, B., Gervasconi, D., Grisar, T., Luppi, P. H., & Fort, P. (2008). Sleep architecture of the melanin-concentrating hormone receptor 1-knockout mice. European Journal of Neuroscience, 27 (7), 1793-800. doi:10.1111/j.1460-9568.2008.06129.x

Gigliobianco, T., Lakaye, B., Makarchikov, A. F., Wins, P., & Bettendorff, L. (2008). Adenylate Kinase-Independent Thiamine Triphosphate Accumulation under Severe Energy Stress in Escherichia Coli. BMC Microbiology, 8, 16. doi:10.1186/1471-2180-8-16

Tyhon, A.* , Lakaye, B.* , Adamantidis, A., & Tirelli, E. (2008). Amphetamine- and cocaine-induced conditioned place preference and concomitant psychomotor sensitization in mice with genetically inactivated melanin-concentrating hormone MCH(1) receptor. European Journal of Pharmacology, 599 (1-3), 72-80. doi:10.1016/j.ejphar.2008.09.027

Tyhon, A.* , Lakaye, B.* , Grisar, T., & Tirelli, E. (2008). Deletion of Melanin-Concentrating Hormone Receptor-1 gene accentuates D-amphetamine-induced psychomotor activation but neither the subsequent development of sensitization nor the expression of conditioned activity in mice. Pharmacology, Biochemistry and Behavior, 88, 446-55. doi:10.1016/j.pbb.2007.10.001

Coumans, B., Grisar, T., Nahon, J. L., & Lakaye, B. (04 October 2007). Effect of ppMCH derived peptides on PBMC proliferation and cytokine expression. Regulatory Peptides, 143 (1-3), 104-108. doi:10.1016/j.regpep.2007.04.001

Duncan, E. A., Sorrell, J. E., Adamantidis, A., Rider, T., Jandacek, R. J., Seeley, R. J., Lakaye, B., & Woods, S. C. (August 2007). Alcohol drinking in MCH receptor-1-deficient mice. Alcoholism, Clinical and Experimental Research, 31 (8), 1325-1337. doi:10.1111/j.1530-0277.2007.00427.x

Tyhon, A., Adamantidis, A., Foidart, A., Grisar, T., Lakaye, B., & Tirelli, E. (02 October 2006). Mice lacking the melanin-concentrating hormone receptor-1 exhibit an atypical psychomotor susceptibility to cocaine and no conditioned cocaine response. Behavioural Brain Research, 173 (1), 94-103. doi:10.1016/j.bbr.2006.06.007

de Nijs, L., Lakaye, B., Coumans, B., Leon, C., Ikeda, T., Delgado-Escueta, A. V., Grisar, T., & Chanas, G. (10 September 2006). EFHC1, a protein mutated in juvenile myoclonic epilepsy, associates with the mitotic spindle through its N-terminus. Experimental Cell Research, 312 (15), 2872-2879. doi:10.1016/j.yexcr.2006.05.011

Grisar, T., de Nijs, L., Chanas, G., Leon, C., Coumans, B., Foidart, A., & Lakaye, B. (2006). Some genetic and biochemical aspects of myoclonus. Neurophysiologie Clinique, 36 (5-6, Sep-Dec), 271-279. doi:10.1016/j.neucli.2006.11.002

Adamantidis, A., Thomas, E., Foidart, A., Tyhon, A., Coumans, B., Minet, A., Tirelli, E., Seutin, V., Grisar, T., & Lakaye, B. (15 November 2005). Disrupting the melanin-concentrating hormone receptor 1 in mice leads to cognitive and NMDA response deficit. Journal of the Neurological Sciences, 238 (Suppl. 1), 288.

Adamantidis, A., Thomas, E., Foidart, A., Tyhon, A., Coumans, B., Minet, A., Tirelli, E., Seutin, V., Grisar, T., & Lakaye, B. (2005). Disrupting the melanin-concentrating hormone receptor 1 in mice leads to cognitive deficits and alterations of NMDA receptor function. European Journal of Neuroscience, 21 (10), 2837-44. doi:10.1111/j.1460-9568.2005.04100.x

Szyniarowski, P., Lakaye, B., Czerniecki, J., Makarchikov, A. F., Wins, P., Margineanu, I., Coumans, B., Grisar, T., & Bettendorff, L. (2005). Pig tissues express a catalytically inefficient 25-kDa thiamine triphosphatase: Insight in the catalytic mechanisms of this enzyme. Biochimica et Biophysica Acta - General Subjects, 1725 (1), 93-102. doi:10.1016/j.bbagen.2005.05.026

Lakaye, B., Adamantidis, A., Coumans, B., & Grisar, T. (16 April 2004). Promoter characterization of the mouse melanin-concentrating hormone receptor 1. Biochimica et Biophysica Acta-Gene Structure and Expression, 1678 (1), 1-6. doi:10.1016/j.bbaexp.2004.01.006

Czerniecki, J., Chanas, G., Verlaet, M., Bettendorff, L., Makarchikov, A. F., Leprince, P., Wins, P., Grisar, T., & Lakaye, B. (2004). Neuronal localization of the 25-kDa specific thiamine triphosphatase in rodent brain. Neuroscience, 125 (4), 833-840. doi:10.1016/j.neuroscience.2004.02.033

Lakaye, B., Makarchikov, A. F., Wins, P., Margineanu, I., Roland, S., Lins, L., Aichour, R., Lebeau, L., Elmoualij, B., Zorzi, W., Coumans, B., Grisar, T., & Bettendorff, L. (2004). Human recombinant thiamine triphosphatase: purification, secondary structure and catalytic properties. International Journal of Biochemistry and Cell Biology, 36 (7), 1348-1364. doi:10.1016/j.biocel.2003.11.013

Lakaye, B., Verlaet, M., Dubail, J., Czerniecki, J., Bontems, S., Makarchikov, A. F., Wins, P., Piette, J., Grisar, T., & Bettendorff, L. (2004). Expression of 25 kDa thiamine triphosphatase in rodent tissues using quantitative PCR and characterization of its mRNA. International Journal of Biochemistry and Cell Biology, 36 (10), 2032-2041. doi:10.1016/j.biocel.2004.03.004

Lakaye, B., Wirtzfeld, B., Wins, P., Grisar, T., & Bettendorff, L. (2004). Thiamine triphosphate, a new signal required for optimal growth of Escherichia coli during amino acid starvation. Journal of Biological Chemistry, 279 (17), 17142-17147. doi:10.1074/jbc.M313569200

Bettendorff, L., Nghiem, H. O., Wins, P., & Lakaye, B. (2003). A general method for the chemical synthesis of gamma-P-32-labeled or unlabeled nucleoside 5 '-triphosphates and thiamine triphosphate. Analytical Biochemistry, 322 (2), 190-197. doi:10.1016/j.ab.2003.08.013

Makarchikov, A. F., Lakaye, B., Gulyai, I. E., Czerniecki, J., Coumans, B., Wins, P., Grisar, T., & Bettendorff, L. (2003). Thiamine triphosphate and thiamine triphosphatase activities: from bacteria to mammals. Cellular and Molecular Life Sciences, 60 (7), 1477-1488. doi:10.1007/s00018-003-3098-4

Ruelle, V., Zorzi, W., Elmoualij, B., Pierard, O., Heinen, E., Lakaye, B., Bettendorff, L., Rees, J., Voorhees, K., & De Pauw, E. (2003). Fingerprint matching of genetically modified E.coli strains by MALDI-TOF Mass Spectrometry of whole cells using a k-nearest-neighbors approach [Poster presentation]. 8th Conference on Food Microbiology. 19-20 Juin 2003. Liège – Belgique.

Verlaet, M., Adamantidis, A., Coumans, B., Chanas, G., Zorzi, W., Heinen, E., Grisar, T., & Lakaye, B. (11 September 2002). Human immune cells express ppMCH mRNA and functional MCHR1 receptor. FEBS Letters, 527 (1-3), 205-210. doi:10.1016/S0014-5793(02)03232-5

Lakaye, B., Dubus, A., Joris, B., & Frère, J.-M. (September 2002). Method for estimation of low outer membrane permeability to beta-lactam antibiotics. Antimicrobial Agents and Chemotherapy, 46 (9), 2901-2907. doi:10.1128/AAC.46.9.2901-2907.2002

Bettendorff, L., Lakaye, B., Margineanu, I., Grisar, T., & Wins, P. (2002). ATP-driven, Na(+)-independent inward Cl- pumping in neuroblastoma cells. Journal of Neurochemistry, 81 (4), 792-801. doi:10.1046/j.1471-4159.2002.00858.x

Charlier, T., Lakaye, B., Ball, G. F., & Balthazart, J. (2002). Steroid receptor coactivator SRC-1 exhibits high expression in steroid-sensitive brain areas regulating reproductive behaviors in the quail brain. Neuroendocrinology, 76 (5), 297-315. doi:10.1159/000066624

Lakaye, B., Makarchikov, A. F., Antunes, A. F., Zorzi, W., Coumans, B., De Pauw, E., Wins, P., Grisar, T., & Bettendorff, L. (2002). Molecular characterization of a specific thiamine triphosphatase widely expressed in mammalian tissues. Journal of Biological Chemistry, 277 (16), 13771-13777. doi:10.1074/jbc.M111241200

Lakaye, B., Thomas, E., Minet, A., & Grisar, T. (2002). The genetic absence epilepsy rat from Strasbourg (GAERS), a rat model of absence epilepsy: Computer modeling and differential gene expression. Epilepsia, 43 (Suppl. 5), 123-129. doi:10.1046/j.1528-1157.43.s.5.17.x

Makarchikov, A. F., Luchko, A. A., Bettendorff, L., Lakaye, B., & Wins, P. (2002). Study of the role of ionogenic amino-acid residues in catalytic activity of thiamine triphosphatase from bovine kidney by means of chemical modification. News of Biomedical Sciences, 3, 66-70.

Ruelle, V., Zorzi, W., Elmoualij, B., Lakaye, B., Heinen, E., & De Pauw, E. (2002). Detection of minor variations between genetically modified and wild-type E.coli strains by Matrix-assisted Laser Desorption/Ionization Mass Spectrometry of whole cells [Poster presentation]. Euroanalysis – European Conference on Analytical Chemistry. September 8-13, 2002. Dortmund – Germany.

Charlier, T., Lakaye, B., Ball, G. F., & Balthazart, J. (2001). Cloning and distribution of steroid receptor coactivator SRC-1 in quail [Poster presentation]. 31st Annual Meeting o the Society for Neuroscience, San Diego, United States.

Lakaye, B., de Borman, B., Minet, A., Arckens, L., Vergnes, M., Marescaux, C., & Grisar, T. (March 2000). Increased Expression of mRNA Encoding Ferritin Heavy Chain in Brain Structures of a Rat Model of Absence Epilepsy. Experimental Neurology, 162 (1), 112-20. doi:10.1006/exnr.2000.7303

Foidart, A., Lakaye, B., Grisar, T., Ball, G. F., & Balthazart, J. (05 September 1999). Estrogen Receptor-Beta in Quail: Cloning, Tissue Expression and Neuroanatomical Distribution. Journal of Neurobiology, 40 (3), 327-42. doi:10.1002/(SICI)1097-4695(19990905)40:3<327::AID-NEU5>3.0.CO;2-L

de Borman, B., Lakaye, B., Minet, A., Zorzi, W., Vergnes, M., Marescaux, C., & Grisar, T. (10 February 1999). Expression of Mrna Encoding Alpha1e and Alpha1g Subunit in the Brain of a Rat Model of Absence Epilepsy. Neuroreport, 10 (3), 569-74. doi:10.1097/00001756-199902250-00023

Ball, G. F., Bernard, D. J., Foidart, A., Lakaye, B., & Balthazart, J. (1999). Steroid sensitive sites in the avian brain: does the distribution of the estrogen receptor alpha and beta types provide insight into their function? Brain, Behavior and Evolution, 54, 28-40. doi:10.1159/000006609

Grisar, T., Lakaye, B., Thomas, E., Bettendorff, L., & Minet, A. (1999). The Molecular Neuron-Glia Couple and Epileptogenesis. Advances in Neurology, 79, 591-602.

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