Cawez, F., Mercuri, P., Piccirilli, A., Perilli, M., Morales Yánez, F. J., Dumoulin, M., & Galleni, M. (02 June 2023). Selection and characterization of anti-NDM-1 nanobodies [Poster presentation]. 14 th Beta-Lactam and beta-lactamase meeting, L'Aquila, Italy. |
Cawez, F., Mercuri, P., Morales Yánez, F. J., Maalouf, R., Vandevenne, M., Kerff, F., Guérin, V., Mainil, J., Thiry, D., Saulmont, M., Vanderplasschen, A., Lafaye, P., Aymé, G., Bogaerts, P., Dumoulin, M., & Galleni, M. (2023). Development of Nanobodies as Theranostic Agents against CMY-2-Like Class C b-Lactamases. Antimicrobial Agents and Chemotherapy. doi:10.1128/aac.01499-22 |
Zouaoui, E., Mercuri, P., Radaoui, A., Ben Salah, N., Galleni, M., Ben-Mahrez, K., & Réjiba, S. (2023). High Prevalence of blaNDM Among Carbapenem Non‑Susceptible Klebsiella pneumoniae in a Tunisian Hospital First Report of blaNDM‑9, blaKPC‑20, and blaKPC‑26 Genes. Current Microbiology, 80 (152). doi:10.1007/s00284-023-03268-2 |
Gavara, L., Verdirosa, F., Sevaille, L., Legru, A., Corsica, G., Nauton, L., Mercuri, P., Sannio, F., De Luca, F., Hadjadj, M., Cerboni, G., Vo Hoang, Y., Licznar-Fajardo, P., Galleni, M., Docquier, J.-D., & Hernandez, J.-F. (11 August 2022). 1,2,4-Triazole-3-thione analogues with an arylakyl group at position 4 as metallo-β-lactamase inhibitors. Bioorganic and Medicinal Chemistry, 72, 116964. doi:10.1016/j.bmc.2022.116964 |
Verdirosa, F.* , Gavara, L.* , Sevaille, L., Tassone, G., Corsica, G., Legru, A., Feller, G., Chelini, G., Mercuri, P., Tanfoni, S., Sannio, F., Benvenuti, M., Cerboni, G., De Luca, F., Bouajila, E., Hoang, Y. V., Licznar-Fajardo, P., Galleni, M., Pozzi, C., ... Hernandez, J.-F.*. (20 January 2022). 1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-β-Lactamase Inhibitors. ChemMedChem, 17 (7), 202100699. doi:10.1002/cmdc.202100699 * These authors have contributed equally to this work. |
Guérin, V., Farchi, A., Thiry, D., Cawez, F., Mercuri, P., Galleni, M., Mainil, J., & Saulmont, M. (2022). Seven-Year Evolution of β-Lactam Resistance Phenotypes in Escherichia coli Isolated from Young Diarrheic and Septicaemic Calves in Belgium. Veterinary Sciences. doi:10.3390/vetsci9020045 |
Lupo, V., Mercuri, P., Frère, J.-M., Joris, B., Galleni, M., Baurain, D.* , & Kerff, F.*. (2022). An Extended Reservoir of Class-D Beta-Lactamases in Non-Clinical Bacterial Strains. Microbiology Spectrum, 10 (2), 0031522. doi:10.1128/spectrum.00315-22 * These authors have contributed equally to this work. |
de Barsy, M., Mercuri, P., Oueslati, S., Elisée, E., Huang, T.-D., Sacré, P., Iorga, B. I., Naas, T., Galleni, M., & Bogaerts, P. (18 October 2021). Detection and Characterization of VIM-52, a New Variant of VIM-1 from a Klebsiella pneumoniae Clinical Isolate. Antimicrobial Agents and Chemotherapy, 65 (Issue 11), 02660-20. doi:10.1128/AAC.02660-20 |
Piccirilli, A., Mercuri, P., Segatore, B., Galleni, M., Brisdelli, F., Kerff, F., Amicosante, G., & Perilli, M. (June 2021). Laboratory Variants GESG170L, GESG170K, and GESG170H Increase Carbapenem Hydrolysis and Confer Resistance to Clavulanic Acid. Antimicrobial Agents and Chemotherapy, 65 (6), 01931-20. doi:10.1128/AAC.01931-20 |
Toncheva-Moncheva, N., Aqil, A., Galleni, M., & Jérôme, C. (June 2021). Conversion of electrospun chitosan into chitin: a robust strategy to tune the properties of 2D biomimetic nanofiber scaffolds. Polysaccharides, 2 (2), 271-286. doi:10.3390/polysaccharides2020019 |
Collet, L., Vander Wauven, C., Dutoit, R., Oudjama, Y., & Galleni, M. (2021). Glycoside hydrolase family 5: structural snapshots highlighting the involvement of two conserved residues in catalysis. Acta Crystallographica. Section D, Structural Biology. doi:10.1107/S2059798320015557 |
Gavara, L., Legru, A., Verdirosa, F., Sevaille, L., Nauton, L., Corsica, G., Mercuri, P., Sannio, F., Feller, G., Coulon, R., De Luca, F., Cerboni, G., Tanfoni, S., Chelini, G., Galleni, M., Docquier, J.-D., & Hernandez, J.-F. (2021). 4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors. Bioorganic Chemistry, 113. doi:10.1016/j.bioorg.2021.105024 |
Guérin, V., Thiry, D., Lucas, P., Blanchard, Y., Cawez, F., Mercuri, P., Galleni, M., Saulmont, M., & Mainil, J. (2021). Identification of b-Lactamase-Encoding (bla) Genes in Phenotypically b-Lactam-Resistant Escherichia coli Isolated from Young Calves in Belgium. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease. doi:10.1089/mdr.2020.0472 |
Piccirilli, A., Criscuolo, E., Brisdelli, F., Mercuri, P., Cherubini, S., De Scicio, M. L., Maccarrone, M., Galleni, M., Amicosante, G., & Perilli, M. (2021). Exploring the Role of L10 Loop in New Delhi Metallo- beta-lactamase (NDM-1): Kinetic and Dynamic Studies. Molecules, 26, 5489. doi:10.3390/molecules26185489 |
Mercuri, P., Esposito, R., Blétard, S., Di Costanzo, S., Perilli, M., Kerff, F., & Galleni, M. (2020). Mutational Effects on Carbapenem Hydrolysis of YEM-1, a New Subclass B2 Metallo-β-Lactamase from Yersinia mollaretii. Antimicrobial Agents and Chemotherapy. doi:10.1128/AAC.00105-20 |
Ceasar, S. A., Lekeux, G., Motte, P., Xiao, Z., Galleni, M., & Hanikenne, M. (2020). di-Cysteine Residues of the Arabidopsis thaliana HMA4 C-Terminus Are Only Partially Required for Cadmium Transport. Frontiers in Plant Science, 11, 560. doi:10.3389/fpls.2020.00560 |
Gavara, L., Sevaille, L., De Luca, F., Mercuri, P., Bebrone, C., Feller, G., Legru, A., Cerboni, G., Tanfoni, S., Baud, D., Cutolo, G., Bestgen, B., Chelini, G., Verdirosa, F., Sannio, F., Pozzi, C., Benvenuti, M., Kwapien, K., Fischer, M., ... Hernandez, J.-F. (2020). 4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-beta-lactamase inhibitors. European Journal of Medicinal Chemistry, 208, 112720. doi:10.1016/j.ejmech.2020.112720 |
Gavara, L., Verdirosa, F., Legru, A., Mercuri, P., Nauton, L., Sevaille, L., Feller, G., Berthomieu, D., Sannio, F., Marcoccia, F., Tanfoni, S., De Luca, F., Gresh, N., Galleni, M., Docquier, J.-D., & Hernandez, J.-F. (2020). 4-(N-Alkyl- and -Acyl-amino)-1,2,4-triazole-3-thione Analogs as Metallo-Beta-Lactamase Inhibitors: Impact of 4-Linker on Potency and Spectrum of Inhibition. Biomolecules, 10 (8), 1094. doi:10.3390/biom10081094 |
Mack, A. R., Barnes, M. D., Taracila, M. A., Hujer, A. M., Hujer, K. M., Cabot, G., Feldgarden, M., Haft, D. H., Klimke, W., Van Den Akker, F., Vila, A. J., Smania, A., Haider, S., Papp-Wallace, K. M., Bradford, P. A., Rossolini, G. M., Docquier, J.-D., Frère, J.-M., Galleni, M., ... Bonomo, R. A. (2020). A standard numbering scheme for class C β-lactamases. Antimicrobial Agents and Chemotherapy, 64 (3). doi:10.1128/AAC.01841-19 |
Mercuri, P., Esposito, R., Blétard, S., Di Costanzo, S., Perilli, M., Kerff, F., & Galleni, M. (22 June 2019). Mutational Effects in Carbapenem Hydrolysis of YEM-1, a New Sub-Class B2 Metallo-beta-Lactamase from Yersinia mollaretii [Poster presentation]. asm microbe, San Francisco Ca, United States. |
De Franco, S., Vandenameele, J., Brans, A., Verlaine, O., Bendak, K., Damblon, C., Matagne, A., Segal, D., Galleni, M., Mackay, J., & Vandevenne, M. (21 February 2019). Exploring the suitability of RanBP2-type Zinc Fingers for RNA-binding protein design. Scientific Reports, 9 (1), 2484. doi:10.1038/s41598-019-38655-y |
Belet, A., Dondelinger, M., Gommes, C., Galleni, M., & Heinrichs, B. (2019). Enzyme Immobilization on Ordered Mesoporous Materials [Paper presentation]. XX International Sol-Gel Conference, Saint- Petersbourg, Russia. |
Lekeux, G.* , Crowet, J.-M.* , Nouet, C., Joris, M., Jadoul, A., Bosman, B., Carnol, M., Motte, P., Lins, L., Galleni, M., & Hanikenne, M. (2019). Homology modeling and in vivo functional characterization of the zinc permeation pathway in a heavy metal P-type ATPase. Journal of Experimental Botany, 70, 329-341. doi:10.1093/jxb/ery353 * These authors have contributed equally to this work. |
Guérin, V., Thiry, D., Galleni, M., Saulmont, M., & Mainil, J. (26 October 2018). β-lactamase-encoding gene identification by microarrays in phenotypically resistant Escherichia coli from young calves in Wallonia, Belgium [Paper presentation]. 5th FARAH DAY. |
Dondelinger, M., Filée, P., Sauvage, E., Quinting, B., Muyldermans, S., Galleni, M., & Vandevenne, M. (16 October 2018). Understanding the significance and implications of antibody numbering and antigen-binding surface/residue definition. Frontiers in Immunology, 9 (OCT). doi:10.3389/fimmu.2018.02278 |
Guérin, V., Thiry, D., Galleni, M., Saulmont, M., & Mainil, J. (August 2018). Beta-lactamase-encoding gene identification by micro-arrays in phenotypically resistant pathogenic Escherichia coli from young calves in Wallonia, Belgium [Paper presentation]. The 30th World Buiatric Congress 2018 Sapporo, Sapporo, Japan. |
Cawez, F., Duray, E., Hu, Y., Vandenameele, J., Romao, E., Vinckle, C., Dumoulin, M., Galleni, M., Muyldermans, S., & Vandevenne, M. (25 May 2018). Combinatorial Design of a Nanobody that Specifically Targets Structured RNAs. Journal of Molecular Biology, 430 (11), 1652-1670. doi:10.1016/j.jmb.2018.03.032 |
Vandevenne, M., Dondelinger, M., Yunus, S., Freichels, A., Freichels, R., Crasson, O., Rhazi, N., Bogaerts, P., Galleni, M., & Filée, P. (2018). The use of a β-lactamase – based conductimetric biosensor assay to detect biomolecular interactions. Journal of Visualized Experiments, (132). doi:10.3791/55414 |
Lekeux, G., Laurent, C., Joris, M., Jadoul, A., Jiang, D., Bosman, B., Carnol, M., Motte, P., Xiao, Z., Galleni, M., & Hanikenne, M. (2018). di-Cysteine motifs in the C-terminus of plant HMA4 proteins confer nanomolar affinity for zinc and are essential for HMA4 function in vivo. Journal of Experimental Botany, 69 (22), 5547-5560. doi:10.1093/jxb/ery311 |
Marcoccia, F., Mercuri, P., Galleni, M., Celenza, G., Amicosante, G., & Perilli, M. (2018). A Kinetic Study of the Replacement by Site Saturation Mutagenesis of Residue 119 in NDM-1 Metallo- beta-Lactamase. Antimicrobial Agents and Chemotherapy, 62 (8). doi:10.1128/AAC.02541-17 |
Pérez-Llarena, F. J., Vázquez-Ucha, J. C., Kerff, F., Zamorano, L., Beceiro, A., Miro, E., Póvoa Cabral, M., Fleites, A., Lantero, M., Martínez-Martínez, L., Martínez-Martínez, A., Galleni, M., Navarro, F., & Bou, G. (2018). Increased antimicrobial resistance in a novel CMY-54 AmpC-type enzyme with a GluLeu217-218 insertion in the Ω-loop. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease. doi:10.1089/mdr.2017.0017 |
Piccirilli, A., Mercuri, P., Galleni, M., Aschi, M., Matagne, A., Amicosante, G., & Perilli, M. (2018). P174E Substitution in GES-1 and GES-5 beta-Lactamases Improves Catalytic Efficiency toward Carbapenems. Antimicrobial Agents and Chemotherapy, 62 (5). doi:10.1128/AAC.01851-17 |
Ramalapa, B., Crasson, O., Vandevenne, M., Galleni, M., & Frank, B. (06 September 2017). Protein-polysaccharide complexes, a tool for protein delivery in CaCO3 microparticles [Poster presentation]. Annual Conference of the European Society of Biomaterials, Athens, Greece. |
Ramalapa, B., Crasson, O., Vandevenne, M., Emmanuel, G., Alain, G., Galleni, M., Boury, F., & Cordonnier, T. (16 August 2017). Protein–polysaccharide complexes for enhanced protein delivery in hyaluronic acid templated calcium carbonate microparticles. Journal of Materials Chemistry B, 5, 7360-7368. doi:10.1039/C7TB01538K |
Lekeux, G., Laurent, C., Xiao, Z., Crowet, J.-M., Lins, L., Hanikenne, M., & Galleni, M. (24 July 2017). Functional and structural characterisation of the Arabidopsis thaliana HMA4 protein [Poster presentation]. Cell Biology of Metals - Godon Research Conference, West Dover, United States. |
Ramalapa, B., Crasson, O., Vandevenne, M., Galleni, M., & Frank, B. (17 July 2017). Protein-polysaccharide complexes for improved protein delivery within CaCO3 microparticles [Paper presentation]. Controlled Release Society Meeting, Boston, United States. |
Rodríguez, M. M., Herman, R., Ghiglione, B., Kerff, F., D'Amico González, G., Bouillenne, F., Galleni, M., Handelsman, J., Charlier, P., Gutkind, G., Sauvage, E., & Power, P. (July 2017). Crystal Structure and Kinetic Analysis of the Class B3 Di-Zinc Metallo-β-Lactamase LRA-12 from an Alaskan Soil Metagenome. PLoS ONE, 12 (7), 0182043. doi:10.1371/journal.pone.0182043 |
Amisano, F., Silvestri, M., Mercuri, P., Gagliardi, A., Bini, L., Frère, J.-M., & Galleni, M. (17 June 2017). Study of the outer membrane permeability of Pseudomonas aeruginosa to ß-lactam antibiotics [Poster presentation]. 13th Beta lactamase meeting, Santo Stefano di Sessanio, Italy. |
Marcoccia, F., Melchiorre, C., Robert, C., Mercuri, P., Galleni, M., Celenza, G., Amicosante, G., & Perilli, M. (June 2017). NDM-1 could still evolve: analysis of a random mutagenesis in position 123 [Poster presentation]. 13th β-lactamase Meeting", Santo Stefano di Sessanio, l'Aquila, Italy. |
Mercuri, P., Blétard, S., Kerff, F., & Galleni, M. (June 2017). Characterisation of the sub-class B2 metallo-β-lactamase of Yersinia mollaretii Wauters [Poster presentation]. 13th β-lactamase Meeting", Santo Stefano di Sessanio, l'Aquila, Italy. |
Piccirilli, A., Perilli, M., Mercuri, P., Aschi, M., Segatore, B., Galleni, M., Celenza, G., & Amicosante, G. (June 2017). Replacement of proline 174 with glutamic acid in GES-1 enzyme improve the flexibility of Ω-loop leading to an increase of catalytic efficiency towards carbapenems [Poster presentation]. 13th β-lactamase Meeting", Santo Stefano di Sessanio, l'Aquila, Italy. |
Ramalapa, B., Crasson, O., Vandevenne, M., Galleni, M., & Frank, B. (30 May 2017). Improved encapsulation of proteins within calcium carbonate microparticles by means of protein-polysaccharide complexes [Poster presentation]. Journée Scientifique SFR Santé, Angers, France. |
Chevigne, A., Campizi, V., Szpakowska, M., Bourry, D., Dumez, M.-E., Martins, J. C., Matagne, A., Galleni, M., & Jacquet, A. (2017). The Lys-Asp-Tyr Triad within the Mite Allergen Der p 1 Propeptide Is a Critical Structural Element for the pH-Dependent Initiation of the Protease Maturation. International Journal of Molecular Sciences, 18 (5). doi:10.3390/ijms18051087 |
Crasson, O., Courtade, G., Léonard, R., Aachmann, F., Legrand, F., Parente, R., Baurain, D., Galleni, M., Sorlie, M., & Vandevenne, M. (2017). Human chitotriosidase: Catalytic domain or carbohydrate binding module, who's leading HCHT's biological function. Scientific Reports, 7 (1). doi:10.1038/s41598-017-02382-z |
Sevaille, L., Gavara, L., Bebrone, C., De Luca, F., Nauton, L., Achard, M., Mercuri, P., Tanfoni, S., Borgianni, L., Guyon, C., Lonjon, P., Turan-Zitouni, G., Dzieciolowski, J., Becker, K., Bénard, L., Condon, C., Maillard, L., Martinez, J., Frère, J.-M., ... Hernandez, J.-F. (2017). 1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases. ChemMedChem, 12, 972-985. doi:10.1002/cmdc.201700186 |
De Franco, S., Vandenameele, J., Galleni, M., & Vandevenne, M. (29 June 2016). Exploring potentialities of RanbP2-type Zinc Fingers in RNA-binding proteins design [Poster presentation]. RNA 2016- The RNA Society of Japan 18th Annual Meeting and the 21st Annual Meeting of the RNA Society, Kyoto, Japan. |
Ramalapa, B., Crasson, O., Vandevenne, M., Galleni, M., Boury, F., & Cordonnier, T. (22 March 2016). The use of protein-polysaccharide complexes to enhance protein delivery in CaCO3 microparticles [Paper presentation]. FADEX 2016 Nanoparticles for Medicine, Grenoble, France. |
Bottoni, C., Perilli, M., Marcoccia, F., Piccirilli, A., Pellegrini, C., Colapietro, M., Sabatini, A., Celenza, G., Kerff, F., Amicosante, G., Galleni, M., & Mercuri, P. (2016). Kinetic Studies on CphA Mutants Reveal the Role of the P158-P172 Loop in Activity versus Carbapenems. Antimicrobial Agents and Chemotherapy, 60 (5), 3123-6. doi:10.1128/AAC.01703-15 |
Fernea, A., Galleni, M., & Frère, J.-M. (2016). Kinetics of the Interaction between BAL29880 and LK157 and the Class C β-Lactamase CHE-1. Antimicrobial Agents and Chemotherapy, 60, 1747-1750. doi:10.1128/AAC.02062-15 |
Laurent, C.* , Lekeux, G.* , Ukuwela, A. A., Xiao, Z., Charlier, J.-B., Bosman, B., Carnol, M., Motte, P., Damblon, C., Galleni, M., & Hanikenne, M. (2016). Metal binding to the N-terminal cytoplasmic domain of the PIB ATPase HMA4 is required for metal transport in Arabidopsis. Plant Molecular Biology, 90, 453-466. doi:10.1007/s11103-016-0429-z * These authors have contributed equally to this work. |
Marcoccia, F., Bottoni, C., Sabatini, A., Colapietro, M., Mercuri, P., Galleni, M., Kerff, F., Matagne, A., Celenza, G., Amicosante, G., & Perilli, M. (2016). Kinetic Study of Laboratory Mutants of NDM-1 Metallo-beta-Lactamase and the Importance of an Isoleucine at Position 35. Antimicrobial Agents and Chemotherapy, 60 (4), 2366-72. doi:10.1128/AAC.00531-15 |
Ramalapa, B., Crasson, O., Vandevenne, M., Galleni, M., Cordonnier, T., & Boury, F. (10 December 2015). Design of new delivery systems for therapeutic proteins based on calcium carbonate microspheres [Poster presentation]. Ecole doctorale biologie santé journées scientifique, Nantes, France. |
Crowet, J.-M., Lekeux, G., Hanikenne, M., Brasseur, R., Galleni, M., & Lins, L. (03 December 2015). Molecular modelling of the metal ATPase HMA4 from Arabidopsis halleri [Poster presentation]. IAP 7/44 Meeting: Integrative Protein Science: from small molecules to complex biological systems - iPros. |
Lekeux, G., Laurent, C., Hanikenne, M., & Galleni, M. (03 December 2015). Functional and structural characterization of the Arabidopsis thaliana HMA4 protein [Poster presentation]. IAP 7/44 Meeting - Integrative Protein Science: from small molecules to complex biological systems – iPros, Leuven, Belgium. |
Crasson, O., Rhazi, N., Jacquin, O., Freichels, A., Jérôme, C., Ruth, N., Galleni, M., Filée, P., & Vandevenne, M. (October 2015). Enzymatic functionalization of a nanobody using protein insertion technology. Protein Engineering, Design and Selection, 28 (10), 451-460. doi:10.1093/protein/gzv020 |
Crasson, O., Legrand, F., Léonard, R., Baurain, D., Galleni, M., & Vandevenne, M. (August 2015). The hidden face of the human macrophage chitotriosidase: taking a new look at this enzyme based on the biochemical and phylogenomic analysis of its chitin binding domain [Poster presentation]. Gordon Research Conferences : Cellulosomes, Cellulases & Other Carbohydrate Modifying Enzymes, Andover MA, United States. |
Freichels, R., Delmarcelle, M., Colarusso, A., Kerff, F., Wathelet, B., & Galleni, M. (July 2015). SPECIFICITY OF CLASS I TAGATOSE 1,6-BISPHOSPHATE ALDOLASE ENHANCED TOWARD TAGATOSE 1,6-BISPHOPHATE [Poster presentation]. 12th Biotrans, Vienne, Austria. |
Laurent, C., Lekeux, G., Damblon, C., Hanikenne, M., & Galleni, M. (08 June 2015). Functional and structural characterization of the Arabidopsis halleri HMA4 N-terminal domain [Poster presentation]. IAP meeting. |
Lekeux, G., Laurent, C., Galleni, M., & Hanikenne, M. (08 June 2015). Functional and structural analysis of the Arabidopsis thaliana HMA4 protein [Poster presentation]. AIP meeting 2015. |
Galleni, M., Kerff, F., & Rigali, S. (05 February 2015). Résistance aux antibiotiques : le retour à l’ère prébiotique ? [Paper presentation]. Liège Creative. |
Bouaziz, A., Walgraffe, D., Bouillot, C., Herman, J., FOGUENNE, J., Gothot, A., Louis, R., Hentges, F., Jacquet, A., Mailleux, A.-C., Chevigne, A., Galleni, M., Adam, E., & Dumez, M.-E. (2015). Development of recombinant stable house dust mite allergen Der p 3 molecules for component-resolved diagnosis and specific immunotherapy. Clinical and Experimental Allergy, 45. doi:10.1111/cea.12452 |
Fernea, A., Galleni, M., & Frère, J.-M. (2015). Kinetics of the interaction between avibactam and the CHE-1 class C beta-lactamase. Journal of Antimicrobial Chemotherapy, 70 (3), 951-953. doi:10.1093/jac/dku442 |
Ghiglione, B., Rodriguez, M. M., Herman, R., Curto, L., Dropa, M., Bouillenne, F., Kerff, F., Galleni, M., Charlier, P., Gutkind, G., Sauvage, E., & Power, P. (2015). Structural and Kinetic Insights into the "Ceftazidimase" Behavior of the Extended-Spectrum beta-Lactamase CTX-M-96. Biochemistry, 54 (32), 5072-82. doi:10.1021/acs.biochem.5b00313 |
Pujol, J., Bouillenne, F., Farnir, F., Dufrasne, I., Mainil, J., Galleni, M., Lekeux, P., Bureau, F.* , & Fievez, L.*. (2015). Generation of a soluble recombinant trimeric form of bovine CD40L and its potential use as a vaccine adjuvant in cows. Veterinary Immunology and Immunopathology, 168 (1), 1-13. doi:10.1016/j.vetimm.2015.09.011 * These authors have contributed equally to this work. |
Lekeux, G., Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (14 November 2014). Structural and functional characterization of the Arabidopsis halleri HMA4 protein [Poster presentation]. Journée doctorale Namur "Industrial researches in structural biological chemistry". |
Lekeux, G., Laurent, C., Damblon, C., Galleni, M., & Hanikenne, M. (09 September 2014). Structural and functional analysis of the HMA4 protein [Poster presentation]. Summer school-Chemistry of metals in biological systems. |
Freichels, R., Colarusso, A., Delmarcelle, M., Kerff, F., Wathelet, B., & Galleni, M. (01 June 2014). Structural studies of class I tagatose 1,6-bisphosphate aldolase : Enhanced substrate specificity toward tagatose 1,6-bisphosphate [Poster presentation]. EMBO : Enzyme mechanisms by biological systems, Manchester (UK), United Kingdom. |
Henrottin, J., Zervosen, A., Lemaire, C., Sapunaric, F., Laurent, S., Galleni, M., Van den Eynde, B., Goldman, S., Plenevaux, A., & Luxen, A. (June 2014). Synthesis of N-fluoroalkyl-tryptophan and study of their biological activity as potential substrates for indoleamine 2,3-dioxygenase [Poster presentation]. French-American Chemical society Symposium - FACS XV. |
Crasson, O., Galleni, M., Parente, R. (Other coll.), Vandevenne, M. (Other coll.), & Filée, P. (Other coll.). (15 May 2014). How to build a biological linker dedicated to the engineering of novel drug delivery systems [Poster presentation]. Bioforum. |
Lekeux, G., Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (15 May 2014). Structural and functional analysis of the Arabidopsis halleri HMA4 protein [Poster presentation]. Bioforum 2014. |
Lekeux, G., Laurent, C., Damblon, C., Galleni, M., & Hanikenne, M. (06 May 2014). Structural and functional study of the Arabidopsis halleri HMA4 protein [Poster presentation]. PhytoSYSTEMS day. |
Achour, N. B., Belhadj, O., Galleni, M., Moussa, M. B., & Mercuri, P. (2014). Study of a Natural Mutant SHV-Type beta-Lactamase, SHV-104, from Klebsiella pneumoniae. International Journal of Microbiology, 2014. doi:10.1155/2014/548656 |
Dumez, M.-E., Herman, J., Campizi, V., Galleni, M., Jacquet, A., & Chevigne, A. (2014). Orchestration of an uncommon maturation cascade of the house dust mite protease allergen quartet. Frontiers in Immunology, 5, 138. doi:10.3389/fimmu.2014.00138 |
Herman, J., Thelen, N., Smargiasso, N., Mailleux, A.-C., Luxen, A., Cloes, M., De Pauw, E., Chevigné, A., Galleni, M., & Dumez, M.-E. (2014). Der p 1 is the primary activator of Der p 3, Der p 6 and Der p 9 the proteolytic allergens produced by the house dust mite Dermatophagoides pteronyssinus. Biochimica et Biophysica Acta - General Subjects, 1840 (3), 1117–1124. doi:10.1016/j.bbagen.2013.11.017 |
Perez, A., Perez-Llarena, F. J., Garcia, P., Kerff, F., Beceiro, A., Galleni, M., & Bou, G. (2014). New mutations in ADC-type beta-lactamases from Acinetobacter spp. affect cefoxitin and ceftazidime hydrolysis. Journal of Antimicrobial Chemotherapy. doi:10.1093/jac/dku163 |
Perez-Llarena, F. J., Zamorano, L., Kerff, F., Beceiro, A., Garcia, P., Miro, E., Larrosa, N., Gomez-Bertomeu, F., Mendez, J. A., Gonzalez-Lopez, J. J., Oliver, A., Galleni, M., Navarro, F., & Bou, G. (2014). Genetic and kinetic characterization of the novel AmpC beta-lactamases DHA-6 and DHA-7. Antimicrobial Agents and Chemotherapy. doi:10.1128/AAC.03144-14 |
Power, P., Sauvage, E., Herman, R., Gutkin, G., Galleni, M., Charlier, P., & Kerff, F. (2014). The crystal structure of the carbapenemase OXA-24 in complex with tazobactam reveals evidences about the intereaction with beta-lactamase inhibitors and lysine carboxylation [Poster presentation]. 54th Interscience Conference on Antimicrobial Agents and Chemotherapy, Washington, United States - District of Columbia. |
Ruggiero, M., Kerff, F., Herman, R., Sapunaric, F., Galleni, M., Gutkind, G., Charlier, P., Sauvage, E., & Power, P. (2014). Crystal Structure of the Extended-Spectrum β -Lactamase PER-2 and Insights into the Role of Specific Residues in the Interaction with β -Lactams and β -Lactamase Inhibitors. Antimicrobial Agents and Chemotherapy, 58 (10), 5994-6002. doi:10.1128/AAC.00089-14 |
Lekeux, G., Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (15 November 2013). Structural and functional analysis of the Arabidopsis halleri HMA4 N-terminal domain [Poster presentation]. SFMBBM Doctoral School. |
Huynen, C., Filée, P., Matagne, A., Galleni, M., & Dumoulin, M. (28 August 2013). Class A β -Lactamases as Versatile Scaffolds to Create Hybrid Enzymes: Applications from Basic Research to Medicine. BioMed Research International, 2013, 16. doi:10.1155/2013/827621 |
Van Der Heiden, E., Delmarcelle, M., Lebrun, S., Freichels, R., Brans, A., Vastenavond, C. M., Galleni, M., & Joris, B. (June 2013). A Pathway closely related to the D-tagatose pathway of Gram-Negative Enterobacteria Identified in the Gram-Positive Bacterium Bacillus licheniformis. Applied and Environmental Microbiology, 79 (11), 3511-3515. doi:10.1128/AEM.03918-12 |
Van Der Heiden, E., Delmarcelle, M., Lebrun, S., Freichels, R., Brans, A., Vastenavond, C. M., Galleni, M., & Joris, B. (June 2013). A Pathway closely related to the D-tagatose pathway of Gram-Negative Enterobacteria Identified in the Gram-Positive Bacterium Bacillus licheniformis [Poster presentation]. 7th International conference on Gram-positive Microorganisms, Montecatini, Italy. |
Henrottin, J., Zervosen, A., Lemaire, C., Galleni, M., & Luxen, A. (May 2013). Automated radiosynthesis of 1-(2-[18F]fluoroethyl)-tryptophan, a potential substrate for indoleamine 2,3-dioxygenase PET imaging [Poster presentation]. The 20th International Symposium on Radiopharmaceutical Sciences - ISRS 2013, Jéju, South Korea. |
Lekeux, G., Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (18 April 2013). Structural and functional study of the Arabidopsis halleri HMA4 N-terminal domain [Poster presentation]. Bioforum 2013, Liège, Belgium. |
Sohier, J., Laurent, C., Chevigné, A., Pardon, E., Srinivasan, V., Wernery, U., Lassaux, P., Steyaert, J., & Galleni, M. (15 March 2013). Allosteric inhibition of VIM metallo-beta-lactamase by a camelid nanobody. Biochemical Journal, 450 (3), 477-486. doi:10.1042/BJ20121305 |
Crasson, O., Rhazi, N., Kinet, M. (Other coll.), Filée, P. (Other coll.), Stordeur, P. (Other coll.), Collard, A. (Other coll.), & Galleni, M. (Other coll.). (26 February 2013). Characterization of monoclonal antibodies against Hemolysin Alpha of Staphylococcus aureus [Poster presentation]. IAP meeting "Integrative Protein Science: from small molecules to complex biological systems", Liège, Belgium. |
Freichels, R., Guarino, C., Delmarcelle, M., Kerff, F., Wathelet, B., & Galleni, M. (26 February 2013). Biochemical and Structural studies of the type I tagatose bisphosphate aldolases [Poster presentation]. IAP meeting "integrative protein science : from small molecules to complex biological systems", Liège, Belgium. |
Lekeux, G., Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (26 February 2013). Structural and functional characterization of the Arabidopsis halleri HMA4 N-terminal domain [Poster presentation]. IAP meeting: "Integrative Protein Science: from small molecules to complex biological systems". |
Berlemont, R., Jacquin, O., Delsaute, M., La Salla, M., Georis, J., Verte, F., Galleni, M., & Power, P. (2013). Novel Cold-Adapted Esterase MHlip from an Antarctic Soil Metagenome. Biology, 2 (1), 177-88. doi:10.3390/biology2010177 |
Berlemont, R., Spee, O., Delsaute, M., Lara, Y., Schuldes, J., Simon, C., Power, P., Daniel, R., & Galleni, M. (2013). Novel organic solvent-tolerant esterase isolated by metagenomics: insights into the lipase/esterase classification. Revista Argentina de Microbiologia, (45), 3-12. |
Delsaute, M., Berlemont, R., Dehareng, D., Van Elder, D., Galleni, M., & Bauvois, C. (2013). Three-dimensional structure of RBcel1, a metagenome-derived psychrotolerant family GH5 endoglucanase. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications, 69 (Pt 8), 828-33. doi:10.1107/S1744309113014565 |
Dumez, M.-E., Herman, J., Campisi, V., Bouaziz, A., Rosu, F., Luxen, A., Vandenberghe, I., De Pauw, E., Frère, J.-M., Matagne, A., Chevigne, A., & Galleni, M. (2013). The proline-rich motif of the proDer p 3 allergen propeptide is crucial for protease-protease interaction. PLoS ONE, 8 (9), 68014. doi:10.1371/journal.pone.0068014 |
Perilli, M., Celenza, G., Mercuri, P., Galleni, M., Pellegrini, C., Segatore, B., & Amicosante, G. (2013). R164H and V240H replacements by site-directed mutagenesis of TEM-149 extended-spectrum beta-lactamase: kinetic analysis of TEM-149H240 and TEM-149H164-H240 laboratory mutants. Antimicrobial Agents and Chemotherapy, 57 (2), 1047-9. doi:10.1128/AAC.01268-12 |
Delbrück, H., Bogaerts, P., Kupper, M., Rezende de Castro, R., Bennik, S., Glupczynski, Y., Galleni, M., Hoffmann, K., & Bebrone, C. (November 2012). Kinetic and crystallographic studies of extended-spectrum GES-11, GES-12, and GES-14 β-lactamases. Antimicrobial Agents and Chemotherapy, 56(11), 5618-5625. doi:10.1128/AAC.01272-12 |
Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (November 2012). Study of the structural factors that modulate the metal binding affinity of the N-terminal domain of the Arabidospsis halleri HMA4 [Poster presentation]. YBMRS 2012, Spa, Belgium. |
Laurent, C., Hanikenne, M., & Galleni, M. (September 2012). Study of the structural factors that modulate the metal binding affinity of the Arabidopsis halleri HMA4 [Poster presentation]. Sofia School of Protein Science :Structure and dynamics of biological macromolecules, Sofia, Bulgaria. |
Bouaziz, A., Campisi, V., Herman, J., Walgraffe, D., Jacquet, A., Hentges, F., Emmanuelle, A., Galleni, M., & Dumez, M.-E. (19 June 2012). Analysis of the allergenicity of natural and recombinant Der p 3 [Poster presentation]. 31éme congrès European Academy of allergy and Clinical Immunology, Genève, Switzerland. |
Scarafone, N., Pain, C., Fratamico, A., Gaspard, G., yilmaz, N., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (March 2012). Amyloid-like fibril formation by polyQ proteins: a critical balance between the polyQ length and the constraints imposed by the host protein. PLoS ONE, 7 (3). doi:10.1371/journal.pone.0031253 |
Baldo, A., Chevigné, A., Dumez, M.-E., Mathy, A., Power, P., Tabart, J., Cambier, L., Galleni, M., & Mignon, B. (2012). Inhibition of the keratinolytic subtilisin protease Sub3 from Microsporum canis by its propeptide (proSub3) and evaluation of the capacity of proSub3 to inhibit fungal adherence to feline epidermis. Veterinary Microbiology, 159 (3-4), 479-484. doi:10.1016/j.vetmic.2012.04.041 |
Ben Achour, N., Power, P., Mercuri, P., Ben Moussa, M., Galleni, M., & Belhadj, O. (2012). First detection of a transferable blaCTX-M-14b gene in a Klebsiella pneumoniae clinical isolate from Tunisia and analysis of its genetic context. Annals of Microbiology, 62, 1737-1742. |
Delsaute, M., Berlemont, R., Bauvois, C., Wei, Q., Cornelis, P., & Galleni, M. (2012). Cellulase involvement in the bacterial cellulose biosynthesis [Poster presentation]. Biomedica 2012: Where Science and Business meet, Liège, Belgium. |
Kupper, M., Bauvois, C., Frère, J.-M., Galleni, M., & Bebrone, C. (January 2012). The CphAII protein from Aquifex aeolicus exhibits a metal-dependent phosphodiesterase activity. Extremophiles: Life Under Extreme Conditions, 16(1), 45-55. doi:10.1007/s00792-011-0404-1 |
Moineaux, L., Laurent, S., Reniers, J., Dolusic, E., Galleni, M., Frère, J.-M., Masereel, B., Frederick, R., & Wouters, J. (2012). Synthesis, crystal structures and electronic properties of isomers of chloro-pyridinylvinyl-1H-indoles. European Journal of Medicinal Chemistry, 54, 95-102. doi:10.1016/j.ejmech.2012.04.033 |
Power, P., Mercuri, P., Herman, R., Kerff, F., Gutkind, G., Dive, G., Galleni, M., Charlier, P., & Sauvage, E. (2012). Novel fragments of clavulanate observed in the structure of the class A b-lactamase from Bacillus licheniformis BS3. Journal of Antimicrobial Chemotherapy, 67 (10), 2379-2387. doi:10.1093/jac/dks231 |
Sohier, J., Laurent, C., Chevigné, A., Pardon, E., Srinivasan, V., Lassaux, P., Buys, N., Willibal, K., Steyaert, J., & Galleni, M. (2012). Allosteric inhibition of VIMs metallo-β-lactamases by a camelid single-domain antibody fragment [Poster presentation]. Biomedica 2012. |
Vandevenne, M., Galleni, M., & Filée, P. (2012). How to make good use of a “bad” enzyme: utilization of efficient β-lactamases for the benefits of biochemical research. In J.-M. Frère (Ed.), β-lactamases (pp. 479-503). Indiana, United States: Nova Science. |
Laurent, C., Sohier, J., Pardon, E., Lassaux, P., Buys, N., Willibal, K., Steyaert, J., Wyns, L., & Galleni, M. (10 December 2011). Characterization of the inhibition of metallo-β-lactamases of subclass B1 by VHHs cAbVIM4 and cAbBCII10 [Poster presentation]. journée doctorale SFMBBM, Liège, Belgium. |
Laurent, C., Hanikenne, M., & Galleni, M. (14 October 2011). Insight into the structural factors that modulate the metal binding affinity of the Arabidospsis halleri HMA4 [Paper presentation]. SFMBBM graduate school 5th annual meeting, bruxelles, Belgium. |
Laurent, C., Hanikenne, M., & Galleni, M. (14 October 2011). Insight into the structural factors that modulate the metal binding affinity of the Arabidospsis halleri HMA4 [Poster presentation]. SFMBBM graduate school 5th annual meeting, Bruxelles, Belgium. |
El Garch, F., Bogaerts, P., Bebrone, C., Galleni, M., & Glupczynski, Y. (October 2011). OXA-198, an acquired carbapenem-hydrolyzing class D beta-lactamase from Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy, 55(10), 4828-4833. doi:10.1128/AAC.00522-11 |
Pain, C., Scarafone, N., Maruccia, C., Jaspar, A., Buys, N., Willibal, K., Filée, P., Galleni, M., Matagne, A., Steyaert, J., Pardon, E., & Dumoulin, M. (27 August 2011). Generation of single-domain antidoby fragments raised against proteins containing polyglutamine expansions [Paper presentation]. Amyloid Fibrils, Prions and Precursors: Molecules for Targeted Intervention, Halle, Germany. |
Horsfall, L., Izougarhane, Y., Lassaux, P., Selevsek, N., Liénard, B., Poirel, L., Kupper, M., Hoffmann, K., Frère, J.-M., Galleni, M., & Bebrone, C. (April 2011). Broad antibiotic resistance profile of the subclass B3 metallo-β-lactamase GOB-1, a di-zinc enzyme. FEBS Journal, 278(8), 1252-1263. doi:10.1111/j.1742-4658.2011.08046.x |
Pain, C., Scarafone, N., Jaspar, A., Buys, N., Willibal, K., Filée, P., Galleni, M., Matagne, A., Steyaert, J., Pardon, E., & Dumoulin, M. (25 January 2011). Generation of camelid single-domain antibody fragments raised against proteins containing polyglutamine expansions [Poster presentation]. Interuniversity Attraction Poles, Liège, Belgium. |
Bebrone, C., Delbrück, H., Kupper, M. B., Ervenich, D., Hoffmann, K., & Galleni, M. (2011). The C221D mutation leads to a modification of the Metallo-beta-Lactamase fold of CphA [Poster presentation]. IAP P6/19 project: PROFUSA meeting, Liège, Belgium. |
Bebrone, C., Delbrück, H., Kupper, M. B., Galleni, M., & Hoffmann, K. (2011). The structure of the C221D mutant of the subclass B2 CphA metallo-beta-lactamase shows a modification of the typical alpha beta beta alpha fold [Poster presentation]. 11th β-lactamase meeting, Leonessa, Italy. |
Bebrone, C., Kupper, M. B., Dehareng, D., Frère, J.-M., Hoffmann, K., & Galleni, M. (2011). The CphAII protein from Aquifex aeolicus possesses a metal-dependent phosphodiesterase activity [Poster presentation]. 11th β-lactamase meeting, Leonessa, Italy. |
Berlemont, R., Pipers, Delsaute, M., Angiono, F., Feller, G., Galleni, M., & Power, P. (2011). Exploring the Antarctic soil metagenome as a source of novel cold-adapted enzymes and genetic mobile elements. Revista Argentina de Microbiologia. |
Delsaute, M., Berlemont, R., Paulus, V., Bauvois, C., Wei, Q., Cornelis, P., & Galleni, M. (2011). Cellulase involvement in the cellulose biosynthesis of Pseudomonas stutzeri [Poster presentation]. 13th International Conference on Pseudomonas, Sydney, Australia. |
Dolusic, E., Larrieu, P., Blanc, S., Sapunaric, F., Norberg, B., Moineaux, L., Colette, D., Stroobant, V., Pilotte, L., Colau, D., Ferain, T., Fraser, G., Galleni, M., Frère, J.-M., Masereel, B., Van den Eynde, B., Wouters, J., & Frederick, R. (2011). Indol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors. Bioorganic and Medicinal Chemistry, 19 (4), 1550-61. doi:10.1016/j.bmc.2010.12.032 |
Dolusic, E., Larrieu, P., Blanc, S., Sapunaric, F., Pouyez, J., Moineaux, L., Colette, D., Stroobant, V., Pilotte, L., Colau, D., Ferain, T., Fraser, G., Galleni, M., Frère, J.-M., Masereel, B., Van den Eynde, B., Wouters, J., & Frederick, R. (2011). Discovery and preliminary SARs of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors. European Journal of Medicinal Chemistry, 46 (7), 3058-65. doi:10.1016/j.ejmech.2011.02.049 |
El Garch, F., Bogaerts, P., Bebrone, C., Galleni, M., & Glupczynski, G. (2011). Identification of OXA-198, a new carbapenem hydrolyzing class D beta-lactamase, in Pseudomonas aeruginosa [Poster presentation]. 21th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Milan, Italy. |
Lassaux, P., Traoré, D., Loisel, E., Favier, A., Docquier, J.-D., Sohier, J., Laurent, C., Bebrone, C., Frère, J.-M., Ferrer, J.-L., & Galleni, M. (2011). Biochemical and structural characterization of the subclass B1 metallo-β-lactamase VIM-4. Antimicrobial Agents and Chemotherapy. doi:10.1128/AAC.01486-09 |
Perez-Llarena, F. J., Kerff, F., Abian, O., Mallo, S., Fernandez, M. C., Galleni, M., Sancho, J., & Bou, G. (2011). Distant and new mutations in CTX-M-1 beta-lactamase affect cefotaxime hydrolysis. Antimicrobial Agents and Chemotherapy, 55 (9), 4361-8. doi:10.1128/AAC.00298-11 |
Vandevenne, M., Campisi, V., Freichels, A., Gillard, C., Gaspard, G., Frère, J.-M., Galleni, M., & Filée, P. (2011). Comparative functional analysis of the human macrophage chitotriosidase. Protein Science: A Publication of the Protein Society. doi:10.1002/pro.676 |
Vandevenne, M., GASPARD, G., Belgsir, E. M., Ramnath, M., Cenatiempo, Y., Delneuville, D., Dumoulin, M., Frère, J.-M., Matagne, A., Galleni, M., & Filee, P. (2011). Effects of monopropanediamino-beta-cyclodextrin on the denaturation process of the hybrid protein BlaPChBD. Biochimica et Biophysica Acta. doi:10.1016/j.bbapap.2011.05.007 |
Pain, C., Scarafone, N., Jaspar, A., Buys, N., Willibal, K., Filée, P., Galleni, M., Matagne, A., Steyaert, J., Pardon, E., & Dumoulin, M. (10 December 2010). Generation of camelid single-domain antibody fragments raised against proteins containing polyglutamine expansions [Poster presentation]. Journée des doctorants, Liège, Belgium. |
Toncheva, N., Aqil, A., Croisier, F., Dijkstra, P., Feijen, J., van der Werf, K., Bennink, M., Galleni, M., Poumay, Y., Colige, A., & Jérôme, C. (29 November 2010). Chitosan nanofiber membranes for tissue engineering - synthesis, characterization and properties [Poster presentation]. PAI P6/27 Annual Meeting, Brussels, Belgium. |
Vercheval, L., Di Paolo, A., Borel, F., Ferrer, J.-L., Sauvage, E., Matagne, A., Frère, J.-M., Charlier, P., Galleni, M., & Kerff, F. (25 November 2010). Three factors that modulate the activity of class D β-lactamases and interfere with the post-translational carboxylation of Lys 70. Biochemical Journal, 432 (3), 495-504. doi:10.1042/BJ20101122 |
Pain, C., Scarafone, N., Jaspar, A., Buys, N., Willibal, K., Filée, P., Galleni, M., Matagne, A., Steyaert, J., Pardon, E., & Dumoulin, M. (14 October 2010). Generation of camelid single-domain antibody fragments raised against proteins containing polyglutamine expansions [Poster presentation]. Single Domain Antibodies Come of Age, Ghent, Belgium. |
Filée, P., Rhazi, N., Galleni, M., Taminiau, B., Jolois, O., Collard, A., & Jacquet, A. (22 July 2010). A recombinant alpha-hemolysin polypeptide of Staphylococcus aureus, having deletion in the stem domain and heterologous sequences inserted. |
Scarafone, N., Pain, C., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (07 June 2010). Interplay between the effects of the length of the polyglutamine tract and its structural context on the aggregation of polyglutamine (polyQ) proteins [Poster presentation]. Conférence Jacques Monod : Protein misfolding and aggregation in ageing and disease, Roscoff, France. |
Mallo, S., Pérez-Llarena, F. J., Kerff, F., Fernández-Moreira, E., Soares, N. C., Galleni, M., & Bou, G. (June 2010). A Tripeptide Deletion in the Class C beta-Lactamase FOX-4 Enzyme Impairs Cefoxitin Hydrolysis and Slightly Increases Susceptibility to beta-Lactamase Inhibitors. Journal of Antimicrobial Chemotherapy, 65 (6), 1187-94. doi:10.1093/jac/dkq115 |
Bebrone, C., Lassaux, P., Vercheval, L., Sohier, J., Jehaes, A., Sauvage, E., & Galleni, M. (16 April 2010). Current challenges in antimicrobial chemotherapy: focus on beta-lactamase inhibition. Drugs, 70(6), 651-679. doi:10.2165/11318430-000000000-00000 |
Berlemont, R., Delsaute, M., & Galleni, M. (22 March 2010). Insights into the metagenomic approach : identification and characterization of cellulases involved in bacterial cellulose synthesis [Paper presentation]. 239th American Chemical Society National Meeting & Exposition, San Francisco, United States - California. |
Baldo, A., Mathy, A., Tabart, J., Camponova, P., Vermout, S., Massart, L., Maréchal, F., Galleni, M., & Mignon, B. (2010). Secreted subtilisin Sub3 from Microsporum canis is required for adherence to but not for invasion of the epidermis. British Journal of Dermatology, 162 (5), 990-997. doi:10.1111/j.1365-2133.2009.09608.x |
Berlemont, R., & Galleni, M. (2010). Carbohydrate actives enzymes derived from metagenomes: from microbial ecology to enzymology. In R. W. Li (Ed.), Metagenomics and its Applications in Agriculture, Biomedicine and Environmental Studies (1ère éd). New York, United States: NovaScience. |
Chevigne, A., Dumez, M.-E., Dumoulin, M., Matagne, A., Jacquet, A., & Galleni, M. (2010). Comparative study of mature and zymogen mite cysteine protease stability and pH unfolding. Biochimica et Biophysica Acta, 1800 (9), 937-945. doi:10.1016/j.bbagen.2010.05.011 |
Delsaute, M., Berlemont, R., Renson, T., & Galleni, M. (2010). Cellulases catalysed cellulose polymerisation [Poster presentation]. 35th FEBS Congress: Molecules of Life, Göteborg, Sweden. |
Delsaute, M., Berlemont, R., Renson, T., & Galleni, M. (2010). Cellulase involvement in the cellulose biosynthesis [Poster presentation]. Journée doctorale SFMBBM, Liège, Belgium. |
Geenen, V., Mottet, M., Dardenne, O., Kermani, H., Martens, H., François, J.-M., Galleni, M., Hober, D., Rahmouni, S., & Moutschen, M. (2010). Thymic self-antigens for the design of a negative/tolerogenic self-vaccination against type 1 diabetes. Current Opinion in Pharmacology, 10, 461-472. doi:10.1016/j.coph.2010.04.005 |
Lassaux, P., Delbrück, H., Gulea, M., Kupper, M., Hoffmann, K., Galleni, M., & Bebrone, C. (2010). Interactions mediating the positioning of mercapto-phosphonate inhibitors in the active site of metallo-beta-lactamases [Paper presentation]. ECCMID, Vienne, Austria. |
Lassaux, P., Hamel, M., Gulea, M., Delbrück, H., Mercuri, P., Horsfall, L., Dehareng, D., Kupper, M., Frère, J.-M., Hoffmann, K., Galleni, M., & Bebrone, C. (2010). Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-β-lactamases. Journal of Medicinal Chemistry, 53, 4862–4876. doi:10.1021/jm100213c |
Phichith, D., Bun, S., Padiolleau-Lefevre, S., Guellier, A., Banh, S., Galleni, M., Frère, J.-M., Thomas, D., Friboulet, A., & Avalle, B. (2010). Novel peptide inhibiting both TEM-1 beta-lactamase and penicillin-binding proteins. FEBS Journal, 277 (23), 4965-72. doi:10.1111/j.1742-4658.2010.07906.x |
Rodriguez, M. M., Power, P., Sader, H., Galleni, M., & Gutkind, G. (2010). Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup. Antimicrobial Agents and Chemotherapy, 54 (7), 3070-1. doi:10.1128/AAC.01615-09 |
Sohier, J., Laurent, C., Chevigné, A., Pardon, E., Srinvasan, V., Lassaux, P., Buys, N., Willibal, K., Steyaert, J., & Galleni, M. (2010). Characterisation of B1 metallo-beta-lactamase inhibition by VHHs. |
Sohier, J., Laurent, C., Pardon, E., Lassaux, P., Buys, N., Willibal, K., Steyaert, J., Wyns, L., & Galleni, M. (2010). cAbVIM4, a nanobody inhibiting the metallo-β-lactamase VIM-4 [Poster presentation]. 35th FEBS Congress: Molecules of Life, Göteborg, Sweden. |
Sohier, J., Laurent, C., Pardon, E., Srinivasan, V., Lassaux, P., Buys, N., Willibal, K., Steyaert, J., & Galleni, M. (2010). CA1838, A NANOBODY INHIBITING THE METALLO-β-LACTAMASE VIM-4 [Poster presentation]. Single Domain Antibodies Come of Age. |
Minond, D., Saldanha, S. A., Spaargaren, M., Spicer, T., Fotsing, J. R., Weide, T., Fokin, V. V., Sharpless, K. B., Galleni, M., Bebrone, C., Lassaux, P., & Hodder, P. (15 July 2009). Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries. Bioorganic and Medicinal Chemistry, 17, 5027-37. doi:10.1016/j.bmc.2009.05.070 |
Scarafone, N., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (28 April 2009). Effect of polyQ insertions on the structural, thermodynamic and aggregating properties of the beta-lactamase from B. Licheniformis 749/C (BlaP) [Poster presentation]. Conférence Jacques Monod : Protein folds in infectious and neurodegenerative diseases, Aussois, France. |
Baurin, S., Vercheval, L., Bouillenne, F., Falzone, C., Brans, A., Jacquamet, L., Ferrer, J.-L., Sauvage, E., Dehareng, D., Frère, J.-M., Charlier, P., Galleni, M., & Kerff, F. (2009). Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases. Biochemistry, 48 (47), 11252-63. doi:10.1021/bi901548c |
Bebrone, C., Delbrück, H., Kupper, M., Schlömer, P., Willmann, C., Frère, J.-M., Fisher, R., Galleni, M., & Hoffmann, K. (2009). The structure of the di-zinc subclass B2 metallo-beta-lactamase CphA reveals that the second inhibitory zinc ion binds in the "histidine" site. Antimicrobial Agents and Chemotherapy. doi:10.1128/AAC.00288-09 |
Bebrone, C., Delbrück, H., Wilmann, C., Galleni, M., Frère, J.-M., & Hoffmann, K. (2009). The structure of the di-zinc form of the subclass B2 CphA metallo-β-lactamase reveals that the second zinc ion binds in the Histidine site [Poster presentation]. “Penicillin-recognizing enzymes: from enzyme kinetics to protein folding” symposium, Liège, Belgium. |
Ben Achour, N., Mercuri, P., Ben Moussa, M., Galleni, M., & Belhadj, O. (2009). Characterization of a novel extended-spectrum TEM-type beta-lactamase, TEM-164, in a clinical strain of Klebsiella pneumoniae in Tunisia. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease, 15 (3), 195-9. doi:10.1089/mdr.2009.0900 |
Ben Achour, N., Mercuri, P., Power, P., Belhadj, C., Ben Moussa, M., Galleni, M., & Belhadj, O. (2009). First detection of CTX-M-28 in a Tunisian hospital from a cefotaxime-resistant Klebsiella pneumoniae strain. Pathologie Biologie, 57 (5), 343-8. doi:10.1016/j.patbio.2008.07.016 |
Berlemont, R., Delsaute, M., Pipers, D., D'Amico, S., Feller, G., Galleni, M., & Power, P. (2009). Insights into bacterial cellulose biosynthesis by functional metagenomics on Antarctic soil samples. ISME Journal, 3 (9), 1070-1081. doi:10.1038/ismej.2009.48 |
Gangoue Pieboji, J., Eze, N., Ngongang Djintchui, A., Ngameni, B., Tsabang, N., Pegnyemb, D. E., Biyiti, L., Ngassam, P., Koulla-Shiro, S., & Galleni, M. (2009). The in-vitro antimicrobial activity of some medicinal plants against beta-lactam-resistant bacteria. Journal of Infection in Developing Countries, 3 (9), 671-80. doi:10.3855/jidc.77 |
Pellegrini, C., Mercuri, P., Celenza, G., Galleni, M., Segatore, B., Sacchetti, E., Volpe, R., Amicosante, G., & Perilli, M. (2009). Identification of bla(IMP-22) in Pseudomonas spp. in urban wastewater and nosocomial environments: biochemical characterization of a new IMP metallo-enzyme variant and its genetic location. Journal of Antimicrobial Chemotherapy, 63 (5), 901-8. doi:10.1093/jac/dkp061 |
Scarafone, N., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (September 2008). Chimeric proteins as models to study the mechanism of aggregation associated with polyglutamine expansions [Poster presentation]. 20th Faltertage: Folding in vitro, folding in vivo and folding h.c, Wittenberg, Germany. |
Scarafone, N., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (September 2008). Chimeric proteins as models to study the mechanism of aggregation associated with polyglutamine expansions [Paper presentation]. 20th Faltertage: Folding in vitro, folding in vivo and folding h.c, Wittenberg, Germany. |
Scarafone, N., Filée, Galleni, M., Matagne, A., & Dumoulin, M. (22 July 2008). Creation of chimeric proteins as models to study the mechanism of aggregation associated with polyglutamine expansions [Paper presentation]. 22nd Annual Symposium of The Protein Society, San Diego, United States. |
Scarafone, N., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (20 July 2008). Creation of chimeric proteins as models to study the mechanism of aggregation associated with polyglutamine expansions [Poster presentation]. 22nd Annual Symposium of The Protein Society, San Diego, United States. |
Lenoir, S., Pagnoulle, C., Galleni, M., Compère, P., Jérôme, R., & Detrembleur, C. (22 May 2008). Polyolefin matrixes with permanent antibacterial activity: preparation, antibacterial activity, and action mode of the active species [Poster presentation]. Belgian Polymer Group (BPG) annual meeting 2008, De Haan, Belgium. |
Bebrone, C., Anne, C., Kerff, F., Garau, G., De Vriendt, K., Lantin, R., Devreese, B., Van Beeumen, J., Dideberg, O., Frère, J.-M., & Galleni, M. (2008). Mutational analysis of the zinc- and substrate-binding sites in the CphA metallo-beta-lactamase from Aeromonas hydrophila. Biochemical Journal, 414 (1), 151-9. doi:10.1042/BJ20080375 |
Bebrone, C., Delbrück, H., Kupper, M. B., Galleni, M., Frère, J.-M., & Hoffmann, K. (2008). The structure of the di-zinc form of the subclass B2 CphA metallo-β-lactamase reveals that the second zinc binds in the Histidine site [Poster presentation]. International congress on Biocatalysis BIOCAT, Hambourg, Germany. |
Ben Achour, N., Mercuri, P., Belhadj, C., Ben Moussa, M., Galleni, M., & Belhadj, O. (2008). Cefotaxime and ceftriaxon resistant Klebsiella pneumoniae associated with SHV-11 hyperproduction. Annals of Microbiology, 5 (4), 727-730. doi:10.1007/BF03175582 |
Dumez, M.-E., Teller, N., Mercier, F., Tanaka, T., Vandenberghe, I., Vandenbranden, M., Devreese, B., Luxen, A., Frère, J.-M., Matagne, A., Jacquet, A., Galleni, M., & Chevigne, A. (2008). Activation mechanism of recombinant Der p 3 allergen zymogen - Contribution of cysteine protease Der p 1 and effect of propeptide glycosylation. Journal of Biological Chemistry, 283 (45), 30606-30617. doi:10.1074/jbc.M803041200 |
Javaux, E., Claeys, P., Dehant, V., Galleni, M., Reisse, J., Wilmotte, A., & Nazé, Y. (2008). Astrobiologie. (Geol0263-1, Geol0263-2). |
Lienard, B. M. R., Garau, G., Horsfall, L., Karsisiotis, A. I., Damblon, C., Lassaux, P., Papamicael, C., Roberts, G. C. K., Galleni, M., Dideberg, O., Frère, J.-M., & Schofield, C. J. (2008). Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols. Organic and Biomolecular Chemistry, 6 (13), 2282-2294. doi:10.1039/b802311e |
Lienard, B. M. R., Huting, R., Lassaux, P., Galleni, M., Frère, J.-M., & Schofield, C. J. (2008). Dynamic combinatorial mass spectrometry leads to metallo-beta-lactamase inhibitors. Journal of Medicinal Chemistry, 51 (3), 684-8. doi:10.1021/jm070866g |
Pipers, D., Berlemont, R., Power, P., Collins, T., Feller, G., & Galleni, M. (2008). Isolation of novel hydrolytic genes from an Antarctic metagenomic library [Poster presentation]. 3rd International Conference on Polar and Alpine Microbiology, Banff, Canada. |
Ruth, N., Quinting, B., Mainil, J., Hallet, B., Frère, J.-M., Huygen, K., & Galleni, M. (2008). Creating hybrid proteins by insertion of exogenous peptides into permissive sites of a class A beta-lactamase. FEBS Journal, 275, 5151-5160. doi:10.1111/j.1742-4658.2008.06646.x |
Shimizu-Ibuka, A., Bauvois, C., Sakai, H., & Galleni, M. (2008). Structure of the plasmid-mediated class C beta-lactamase ACT-1. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications, 64 (Pt 5), 334-7. doi:10.1107/S1744309108008531 |
Vandevenne, M., Gaspard, G., Yilmaz, N., Giannotta, F., Frère, J.-M., Galleni, M., & Filée, P. (2008). Rapid and easy development of versatile tools to study protein/ligand interactions. Protein Engineering, Design and Selection. doi:10.1093/protein/gzn021 |
Zervosen, A., Saegerman, C., Antoniotti, I., Robert, B., Ruth, N., Collard, A., Schynts, F., Galleni, M., & Mercuri, P. (2008). Characterization of the cattle serum antibody responses against TEM beta-lactamase and the nonimmunogenic Escherichia coli heat-stable enterotoxin (STaI). FEMS Immunology and Medical Microbiology, 54 (3), 319-329. doi:10.1111/j.1574-695X.2008.00482.x |
Chevigné, A., Barumandzadeh, R., Groslambert, S., Cloes, B., Dehareng, D., Filée, P., Marx, J.-C., Frère, J.-M., Matagne, A., Jacquet, A., & Galleni, M. (16 November 2007). Relationship between propeptide pH unfolding and inhibitory ability during ProDer p 1 activation mechanism. Journal of Molecular Biology, 374 (1), 170-185. doi:10.1016/j.jmb.2007.08.025 |
Lebrun, M., Filée, P., Galleni, M., Mainil, J., Linden, A., & Taminiau, B. (September 2007). Purification of the recombinant beta2 toxin (CPB2) from an enterotoxaemic bovine Clostridium perfringens strain and production of a specific immune serum. Protein Expression and Purification, 55 (1), 119-131. doi:10.1016/j.pep.2007.04.021 |
Faure, E., Halusiak, E., Ruth, N., Gabriel, S., Filée, P., Giannotta, F., Frère, J.-M., Galleni, M., Jérôme, C., & Jérôme, R. (31 August 2007). Biosensors based on electrochemically prepared polyanilines and bifunctional hybrid proteins [Poster presentation]. Polymers: Last achievements and prospects, in honour of Professor Jérôme, Liège, Belgium. |
Horsfall, L. E., Garau, G., Lienard, B. M., Dideberg, O., Schofield, C. J., Frere, J. A., & Galleni, M. (June 2007). Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila. Antimicrobial Agents and Chemotherapy, 51 (6), 2136-2142. doi:10.1128/AAC.00866-06 |
Scarafone, N., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (May 2007). Creation of chimeric proteins as models to study the mechanism of aggregation of proteins with expanded polyglutamine repeats [Poster presentation]. VII European Symposium of The Protein Society, Stockholm-Uppsala, Sweden. |
Cornaglia, G., Akova, M., Amicosante, G., Canton, R., Cauda, R., Docquier, J.-D., Edelstein, M., Frère, J.-M., Fuzi, M., Galleni, M., Giamarellou, H., Gniadkowski, M., Koncan, R., Libisch, B., Luzzaro, F., Miriagou, V., Navarro, F., Nordmann, P., Pagani, L., ... Rossolini, G. M. (April 2007). Metallo-beta-lactamases as emerging resistance determinants in Gram-negative pathogens: open issues. International Journal of Antimicrobial Agents, 29 (4), 380-388. doi:10.1016/j.ijantimicag.2006.10.008 |
Chevigné, A., Yilmaz, N., Gaspard, G., Giannotta, F., François, J.-M., Frère, J.-M., Galleni, M., & Filée, P. (30 March 2007). Use of bifunctional hybrid beta-lactamases for epitope mapping and immunoassay development. Journal of Immunological Methods, 320 (1-2), 81-93. doi:10.1016/j.jim.2006.12.009 |
Rodriguez, M. M., Power, P., Bauvois, C., Di Conza, J., Ayala, J. A., Galleni, M., & Gutkind, G. (March 2007). Characterisation of KLUA-9, a beta-lactamase from extended-spectrum cephalosporin-susceptible Kluyvera ascorbata, and genetic organisation of bla(KLUA-9). International Journal of Antimicrobial Agents, 29 (3), 332-337. doi:10.1016/j.ijantimicag.2006.09.015 |
Lienard, B. M. R., Horsfall, L. E., Galleni, M., Frère, J.-M., & Schofield, C. J. (15 February 2007). Inhibitors of the FEZ-1 metallo-beta-lactamase. Bioorganic and Medicinal Chemistry Letters, 17 (4), 964-968. doi:10.1016/j.bmcl.2006.11.053 |
Ishii, Y., Galleni, M., Ma, L., Frère, J.-M., & Yamaguchi, K. (February 2007). Biochemical characterisation of the CTX-M-14 beta-lactamase. International Journal of Antimicrobial Agents, 29 (2), 159-164. doi:10.1016/j.ijantimicag.2006.09.005 |
Gangoue Pieboji, J., Baurin, S., Frère, J.-M., Ngassam, P., Ngameni, B., Azebaze, A., Pegnyemb, D. E., Watchueng, J., Goffin, C., & Galleni, M. (2007). Screening of some medicinal plants from cameroon for beta-lactamase inhibitory activity. Phytotherapy Research, 21 (3), 284-7. doi:10.1002/ptr.2001 |
Lassaux, P., Hamel, M., Gulea, M., Mercuri, P., Horsfall, L., Bebrone, C., Gaumont, A.-C., Frère, J.-M., & Galleni, M. (2007). Mercapto-phosphonate compounds as broad-spectrum inhibitors of the metallo-beta-lactamases. International Journal of Antimicrobial Agents, 29 (Supplément 2), 95. |
Lebrun, M., Filée, P., Mousset, B., Desmecht, D., Galleni, M., Mainil, J., & Linden, A. (2007). The expression of Clostridium perfringens consensus beta2 toxin is associated with bovine enterotoxaemia syndrome. Veterinary Microbiology, 120 (1-2), 151-157. doi:10.1016/j.vetmic.2006.10.020 |
Scarafone, N., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (2007). Creation of chimeric proteins as models to study the mechanism of aggregation of proteins with expanded polyglutamine repeats [Poster presentation]. Joint Meeting of the Belgian Physical Society and the Belgian Biophysical Society, Antwerpen, Belgium. |
Vandevenne, M., Filée, P., Scarafone, N., Cloes, B., Gaspard, G., Yilmaz, N., Dumoulin, M., François, J.-M., Frère, J.-M., & Galleni, M. (2007). The Bacillus licheniformis BlaP beta-lactamase as a model protein scaffold to study the insertion of protein fragments. Protein Science: A Publication of the Protein Society, 16 (10), 2260-71. doi:10.1110/ps.072912407 |
Scarafone, N., Filée, P., Galleni, M., Dumoulin, M., & Matagne, A. (December 2006). Creation of chimeric proteins as models to study the mechanism of aggregation of polyglutamine proteins [Poster presentation]. Young scientists day, 194th Meeting of the Belgian Society of Biochemistry and Molecular Biology, and International Franqui Chair 2005/2006, Gembloux, Belgium. |
Giannotta, Filée, P., Galleni, M., Frère, J.-M., Joris, B., Brans, A., & Ruth, N. (25 October 2006). Hybrid proteins of active-site serine beta-lactamase. |
chouchani, C., Berlemont, R., masmoudi, A., Galleni, M., Frère, J.-M., belhadj, O., & ben-mahrez, K. (September 2006). A novel extended-spectrum TEM-type beta-lactamase, TEM-138, from Salmonella enterica serovar Infantis. Antimicrobial Agents and Chemotherapy, 50 (9), 3183-5. doi:10.1128/AAC.00388-06 |
Lenoir, S., Pagnoulle, C., Galleni, M., Compère, P., Jérôme, R., & Detrembleur, C. (August 2006). Polyolefin matrixes with permanent antibacterial activity : preparation, antibacterial activity, and action mode of the active species. Biomacromolecules, 7 (8), 2291-2296. doi:10.1021/bm050850c |
Power, P., Galleni, M., Ayala, J. A., & Gutkind, G. (March 2006). Biochemical and molecular characterization of three new variants of AmpC beta-lactamases from Morganella morganii. Antimicrobial Agents and Chemotherapy, 50 (3), 962-967. doi:10.1128/AAC.50.3.962-967.2006 |
De Vriendt, K., Van Driessche, G., Devreese, B., Bebrone, C., Anne, C., Frère, J.-M., Galleni, M., & Van Beeumen, J. (February 2006). Monitoring the zinc affinity of the metallo-beta-lactamase CphA by automated nanoESI-MS. Journal of the American Society for Mass Spectrometry, 17 (2), 180-188. doi:10.1016/j.jasms.2005.10.007 |
Lenoir, S., Pagnoulle, C., Detrembleur, C., Galleni, M., & Jérôme, R. (01 February 2006). New antibacterial cationic surfactants prepared by Atom Transfer Radical Polymerization. Journal of Polymer Science. Part A, Polymer Chemistry, 44 (3), 1214-1224. doi:10.1002/pola.21229 |
Sauvage, E., Fonze, E., Quinting, B., Galleni, M., Frère, J.-M., & Charlier, P. (2006). Crystal structure of the Mycobacterium fortuitum class A beta-lactamase: structural basis for broad substrate specificity. Antimicrobial Agents and Chemotherapy, 50 (7), 2516-21. doi:10.1128/AAC.01226-05 |
Lenoir, S., Pagnoulle, C., Detrembleur, C., Galleni, M., & Jérôme, R. (26 October 2005). Antimicrobial activity of polyestyrene particles coated by photo-crooslinked block copolymers containing a biocidal polymethacrylate block. e-Polymers, 74, 1-11. |
Piette, A., Derouaux, A., Gerkens, P., Noens, E. E. E., Mazzucchelli, G., Vion, S., Koerten, H. K., Titgemeyer, F., De Pauw, E., Leprince, P., van Wezel, G. P., Galleni, M., & Rigali, S. (September 2005). From dormant to germinating spores of Streptomyces coelicolor A3(2): new perspectives from the crp null mutant. Journal of Proteome Research, 4 (5), 1699-708. doi:10.1021/pr050155b |
Bebrone, C., Anne, C., De Vriendt, K., Devreese, B., Rossolini, G. M., Van Beeumen, J., Frère, J.-M., & Galleni, M. (05 August 2005). Dramatic broadening of the substrate profile of the Aeromonas hydrophila CphA metallo-beta-lactamase by site-directed mutagenesis. Journal of Biological Chemistry, 280 (31), 28195-28202. doi:10.1074/jbc.M414052200 |
Lenoir, S., Pagnoulle, C., Detrembleur, C., Galleni, M., & Jérôme, R. (01 June 2005). ATRP of aminated methacrylates: a route to effective antimicrobial surfactants, coatings and additives [Paper presentation]. Advanced nanomaterials for biofunctional surfaces, Liège, Belgium. |
Lenoir, S., Pagnoulle, C., Galleni, M., & Jérôme, R. (19 May 2005). ATRP of aminated methacrylates: a route to effective antimicrobial surfactants, coatings and additives [Paper presentation]. Belgian Polymer Group (BPG) annual meeting 2005, La Roche en Ardenne, Belgium. |
Ruth, N., Mainil, J., Roupie, V., Frère, J.-M., Galleni, M., & Huygen, K. (May 2005). DNA vaccination for the priming of neutralizing antibodies against non-immunogenic STa enterotoxin from enterotoxigenic Escherichia coli. Vaccine, 23 (27), 3618-3627. doi:10.1016/j.vaccine.2004.11.080 |
Garau, G., Bebrone, C., Anne, C., Galleni, M., Frère, J.-M., & Dideberg, O. (28 January 2005). A metallo-beta-lactamase enzyme in action: Crystal structures of the monozinc carbapenemase CphA and its complex with biapenem. Journal of Molecular Biology, 345 (4), 785-795. doi:10.1016/j.jmb.2004.10.070 |
Bauvois, C., Ibuka, A. S., Celso, A., Alba, J., Ishii, Y., Frère, J.-M., & Galleni, M. (2005). Kinetic properties of four plasmid-mediated AmpC beta-lactamases. Antimicrobial Agents and Chemotherapy, 49 (10), 4240-6. doi:10.1128/AAC.49.10.4240-4246.2005 |
Douette, P., Navet, R., Gerkens, P., Galleni, M., Lévy, D., & Sluse, F. (2005). Escherichia coli fusion carrier proteins act as solubilizing agents for recombinant uncoupling protein 1 through interactions with GroEL. Biochemical and Biophysical Research Communications, 333, 686-693. doi:10.1016/j.bbrc.2005.05.164 |
Frère, J.-M., Galleni, M., Bush, K., & Dideberg, O. (2005). Is it necessary to change the classification of ß-lactamases? Journal of Antimicrobial Chemotherapy, 55 (6), 1051-1053. doi:10.1093/jac/dki155 |
Power, P., Galleni, M., Di Conza, J., Ayala, J., & Gutkind, G. (2005). Description of In116, the first blaCTX-M-2-containing complex class 1 integron found in Morganella morganii isolates from Buenos Aires, Argentina. Journal of Antimicrobial Chemotherapy, 55 (4), 461-465. doi:10.1093/jac/dkh556 |
Rodriguez, M. M., Power, P., Radice, M., Vay, C., Famiglietti, A., Galleni, M., Ayala, J. A., & Gutkind, G. (December 2004). Chromosome-encoded CTX-M-3 from Kluyvera ascorbata: a possible origin of plasmid-borne CTX-M-1-derived cefotaximases. Antimicrobial Agents and Chemotherapy, 48 (12), 4895-4897. doi:10.1128/AAC.48.12.4895-4897.2004 |
Ignatova, M., Voccia, S., Gilbert, B., Markova, N., Mercuri, P., Galleni, M., Sciannamea, V., Lenoir, S., Cossement, D., Gouttebaron, R., Jérôme, R., & Jérôme, C. (23 November 2004). Synthesis of copolymer brushes endowed with adhesion to stainless steel surfaces and antibacterial properties by controlled nitroxide-mediated radical polymerization. Langmuir, 20 (24), 10718-10726. doi:10.1021/la048347t |
Mercuri, P., Garcia-Saez, I., De Vriendt, K., Thamm, I., Devreese, B., Van Beeumen, J., Dideberg, O., Rossolini, G. M., Frère, J.-M., & Galleni, M. (06 August 2004). Probing the specificity of the subclass B3 FEZ-1 metallo-beta-lactamase by site-directed mutagenesis. Journal of Biological Chemistry, 279 (32), 33630-33638. doi:10.1074/jbc.M403671200 |
Garau, G., Garcia-Saez, I., Bebrone, C., Anne, C., Mercuri, P., Galleni, M., Frère, J.-M., & Dideberg, O. (July 2004). Update of the standard numbering scheme for class B beta-lactamases. Antimicrobial Agents and Chemotherapy, 48 (7), 2347-2349. doi:10.1128/AAC.48.7.2347-2349.2004 |
Tsang, W. Y., Dhanda, A., Schofield, C. J., Frère, J.-M., Galleni, M., & Page, M. I. (05 April 2004). The inhibition of metallo-beta-lactamase by thioxo-cephalosporin derivatives. Bioorganic and Medicinal Chemistry Letters, 14 (7), 1737-1739. doi:10.1016/j.bmcl.2004.01.047 |
Gérard, S., Galleni, M., Dive, G., & Marchand-Brynaert, J. (02 January 2004). Synthesis and evaluation of N1/C4-substituted beta-lactams as PPE and HLE inhibitors. Bioorganic and Medicinal Chemistry, 12 (1), 129-138. doi:10.1016/j.bmc.2003.10.009 |
Ibuka, A. S., Ishii, Y., Galleni, M., Ishiguro, M., Yamaguchi, K., Frère, J.-M., Matsuzawa, H., & Sakai, H. (16 September 2003). Crystal structure of extended-spectrum beta-lactamase Toho-1: Insights into the molecular mechanism for catalytic reaction and substrate specificity expansion. Biochemistry, 42 (36), 10634-10643. doi:10.1021/bi0342822 |
Alba, J., Bauvois, C., Ishii, Y., Galleni, M., Masuda, K., Ishiguro, M., Ito, M., Frère, J.-M., & Yamaguchi, K. (29 August 2003). A detailed kinetic study of Mox-1, a plasmid-encoded class C beta-lactamase. FEMS Microbiology Letters, 225 (2), 183-188. doi:10.1016/S0378-1097(03)00448-8 |
Garcia-Saez, I., Hopkins, J., Papamicael, C., Franceschini, N., Amicosante, G., Rossolini, G. M., Galleni, M., Frère, J.-M., & Dideberg, O. (27 June 2003). The 1.5-angstrom structure of Chryseobacterium meningosepticum zinc beta-lactamase in complex with the inhibitor, D-captopril. Journal of Biological Chemistry, 278 (26), 23868-23873. |
Moali, C., Anne, C., Lamotte-Brasseur, J., Groslambert, S., Devreese, B., Van Beeumen, J., Galleni, M., & Frère, J.-M. (April 2003). Analysis of the importance of the metallo-beta-lactamase active site loop in substrate binding and catalysis. Chemistry and Biology, 10 (4), 319-329. doi:10.1016/S1074-5521(03)00070-X |
Docquier, J.-D., Lamotte-Brasseur, J., Galleni, M., Amicosante, G., Frère, J.-M., & Rossolini, G. M. (February 2003). On functional and structural heterogeneity of VIM-type metallo-beta-lactamases. Journal of Antimicrobial Chemotherapy, 51 (2), 257-266. doi:10.1093/jac/dkg067 |
Garcia-Saez, I., Mercuri, P., Papamicael, C., Kahn, R., Frère, J.-M., Galleni, M., Rossolini, G. M., & Dideberg, O. (24 January 2003). Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril. Journal of Molecular Biology, 325 (4), 651-660. doi:10.1016/S0022-2836(02)01271-8 |
Bebrone, C., Anne, C., & Galleni, M. (2003). Modification of the specificity of the CphA metallo- β-lactamase produced by Aeromonas hydrophila by site-directed mutagenesis [Poster presentation]. Bioforum, Liège, Belgium. |
Vanhove, M., Zakhem, M., Devreese, B., Franceschini, N., Anne, C., Bebrone, C., Amicosante, G., Rossolini, G. M., Van Beeumen, J., Frère, J.-M., & Galleni, M. (2003). Role of Cys221 and Asn116 in the zinc-binding sites of the Aeromonas hydrophila metallo-beta-lactamase. Cellular and Molecular Life Sciences, 60 (11), 2501-9. doi:10.1007/s00018-003-3092-x |
Prosperi, C., De Seny, D., Llabres, G., Galleni, M., & Lamotte-Brasseur, J. (December 2002). Active-site mutants of class B beta-lactamases: substrate binding and mechanistic study. Cellular and Molecular Life Sciences, 59 (12), 2136-2143. doi:10.1007/s000180200013 |
Wommer, S., Rival, S., Heinz, U., Galleni, M., Frère, J.-M., Franceschini, N., Amicosante, G., Rasmussen, B., Bauer, R., & Adolph, H. W. (05 July 2002). Substrate-activated zinc binding of metallo-beta-lactamases - Physiological importance of the mononuclear enzymes. Journal of Biological Chemistry, 277 (27), 24142-24147. doi:10.1074/jbc.M202467200 |
Docquier, J.-D., Pantanella, F., Giuliani, F., Thaller, M. C., Amicosante, G., Galleni, M., Frère, J.-M., Bush, K., & Rossolini, G. M. (June 2002). CAU-1, a subclass B3 metallo-beta-lactamase of low substrate affinity encoded by an ortholog present in the Caulobacter crescentus chromosome. Antimicrobial Agents and Chemotherapy, 46 (6), 1823-1830. doi:10.1128/AAC.46.6.1823-1830.2002 |
Vessillier, S., Docquier, J.-D., Rival, S., Frère, J.-M., Galleni, M., Amicosante, G., Rossolini, G. M., & Franceschini, N. (June 2002). Overproduction and biochemical characterization of the Chryseobacterium meningosepticum BlaB metallo-beta-lactamase. Antimicrobial Agents and Chemotherapy, 46 (6), 1921-1927. doi:10.1128/AAC.46.6.1921-1927.2002 |
De Seny, D., Prosperi, C., Bebrone, C., Rossolini, G. M., Page, M. I., Noel, P., Frère, J.-M., & Galleni, M. (01 May 2002). Mutational analysis of the two zinc-binding sites of the Bacillus cereus 569/H/9 metallo-beta-lactamase. Biochemical Journal, 363 (Pt 3), 687-696. doi:10.1042/bj3630687 |
Bebrone, C., Anne, C., & Galleni, M. (2002). Molecular evolution of the Aeromonas hydrophila CphA metallo-β-lactamase [Poster presentation]. Engineering enzymes for biocatalysis by using directed evolution, Paris, France. |
Matagne, A., Galleni, M., Laraki, N., Amicosante, G., Rossolini, G., & Frère, J.-M. (2002). Beta-lactamases, an old but ever renascent problem. In A. van Broekhoven (Ed.), Novel Frontiers in the Production of Compounds for Biomedical Use. Dordrecht, Netherlands: Kluwer Academic Publishers. |
Mercuri, P., Ishii, Y., Ma, L., Rossolini, G. M., Luzzaro, F., Amicosante, G., Franceschini, N., Frère, J.-M., & Galleni, M. (2002). Clonal diversity and metallo-beta-lactamase production in clinical isolates of Stenotrophomonas maltophilia. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease, 8 (3), 193-200. doi:10.1089/107662902760326904 |
De Seny, D., Heinz, U., Wommer, S., Kiefer, M., Meyer-Klaucke, W., Galleni, M., Frère, J.-M., Bauer, R., & Adolph, H. W. (30 November 2001). Metal Ion Binding and Coordination Geometry for Wild Type and Mutants of Metallo-Beta -Lactamase from Bacillus Cereus 569/H/9 (Bcii): A Combined Thermodynamic, Kinetic, and Spectroscopic Approach. Journal of Biological Chemistry, 276 (48), 45065-78. doi:10.1074/jbc.M106447200 |
Vilar, M., Galleni, M., Solmajer, T., Turk, B., Frère, J.-M., & Matagne, A. (August 2001). Kinetic Study of Two Novel Enantiomeric Tricyclic Beta-Lactams Which Efficiently Inactivate Class C Beta-Lactamases. Antimicrobial Agents and Chemotherapy, 45 (8), 2215-23. doi:10.1128/AAC.45.8.2215-2223.2001 |
Zervosen, A., Valladares, M. H., Devreese, B., Prosperi, C., Adolph, H.-W., Mercuri, P., Vanhove, M., Amicosante, G., van Beeumen, J., Frère, J.-M., & Galleni, M. (July 2001). Inactivation of Aeromonas Hydrophila Metallo-Beta-Lactamase by Cephamycins and Moxalactam. European Journal of Biochemistry, 268 (13), 3840-50. doi:10.1046/j.1432-1327.2001.02298.x |
Bebrone, C., Moali, C., Mahy, F., Rival, S., Docquier, J.-D., Rossolini, G. M., Fastrez, J., Pratt, R. F., Frère, J.-M., & Galleni, M. (June 2001). Centa as a Chromogenic Substrate for Studying Beta-Lactamases. Antimicrobial Agents and Chemotherapy, 45 (6), 1868-71. doi:10.1128/AAC.45.6.1868-1871.2001 |
Mercuri, P., Bouillenne, F., Boschi, L., Lamotte-Brasseur, J., Amicosante, G., Devreese, B., van Beeumen, J., Frère, J.-M., Rossolini, G. M., & Galleni, M. (April 2001). Biochemical Characterization of the Fez-1 Metallo-Beta-Lactamase of Legionella Gormanii Atcc 33297t Produced in Escherichia Coli. Antimicrobial Agents and Chemotherapy, 45 (4), 1254-62. doi:10.1128/AAC.45.4.1254-1262.2001 |
Galleni, M., Lamotte-Brasseur, J., Rossolini, G. M., Spencer, J., Dideberg, O., & Frère, J.-M. (March 2001). Standard Numbering Scheme for Class B Beta-Lactamases. Antimicrobial Agents and Chemotherapy, 45 (3), 660-3. doi:10.1128/AAC.45.3.660-663.2001 |
Bebrone, C., Fastrez, J., Frère, J.-M., & Galleni, M. (2001). Centa as a chromogenic substrate for the study of β-lactamases [Poster presentation]. Bioforum, Liège, Belgium. |
Bounaga, S., Galleni, M., Laws, A. P., & Page, M. I. (2001). Cysteinyl peptide inhibitors of Bacillus cereus zinc beta-lactamase. Bioorganic and Medicinal Chemistry, 9 (2), 503-10. doi:10.1016/S0968-0896(00)00257-1 |
Conrath, K. E., Lauwereys, M., Galleni, M., Matagne, A., Frère, J.-M., Kinne, J., Wyns, L., & Muyldermans, S. (2001). Beta-lactamase inhibitors derived from single-domain antibody fragments elicited in the camelidae. Antimicrobial Agents and Chemotherapy, 45 (10), 2807-12. doi:10.1128/AAC.45.10.2807-2812.2001 |
Franceschini, N., Boschi, L., Pollini, S., Herman, R., Perilli, M., Galleni, M., Frère, J.-M., Amicosante, G., & Rossolini, G. M. (2001). Characterization of OXA-29 from Legionella (Fluoribacter) gormanii: molecular class D beta-lactamase with unusual properties. Antimicrobial Agents and Chemotherapy, 45 (12), 3509-16. doi:10.1128/AAC.45.12.3509-3516.2001 |
Mollard, C., Moali, C., Papamicael, C., Damblon, C., Vessilier, S., Amicosante, G., Schofield, C. J., Galleni, M., Frère, J.-M., & Roberts, G. C. (2001). Thiomandelic acid, a broad spectrum inhibitor of zinc beta-lactamases: kinetic and spectroscopic studies. Journal of Biological Chemistry, 276 (48), 45015-23. doi:10.1074/jbc.M107054200 |
Boschi, L., Mercuri, P., Riccio, M. L., Amicosante, G., Galleni, M., Frère, J.-M., & Rossolini, G. M. (2000). The Legionella (Fluoribacter) gormanii metallo-beta-lactamase: a new member of the highly divergent lineage of molecular-subclass B3 beta-lactamases. Antimicrobial Agents and Chemotherapy, 44 (6), 1538-43. doi:10.1128/AAC.44.6.1538-1543.2000 |
Chantalat, L., Duee, E., Galleni, M., Frère, J.-M., & Dideberg, O. (2000). Structural effects of the active site mutation cysteine to serine in Bacillus cereus zinc-beta-lactamase. Protein Science: A Publication of the Protein Society, 9 (7), 1402-6. doi:10.1110/ps.9.7.1402 |
Concha, N. O., Janson, C. A., Rowling, P., Pearson, S., Cheever, C. A., Clarke, B. P., Lewis, C., Galleni, M., Frère, J.-M., Payne, D. J., Bateson, J. H., & Abdel-Meguid, S. S. (2000). Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor. Biochemistry, 39 (15), 4288-98. doi:10.1021/bi992569m |
Franceschini, N., Caravelli, B., Docquier, J.-D., Galleni, M., Frère, J.-M., Amicosante, G., & Rossolini, G. M. (2000). Purification and biochemical characterization of the VIM-1 metallo-beta-lactamase. Antimicrobial Agents and Chemotherapy, 44 (11), 3003-7. doi:10.1128/AAC.44.11.3003-3007.2000 |
Hernandez Valladares, M., Kiefer, M., Heinz, U., Soto, R. P., Meyer-Klaucke, W., Nolting, H. F., Zeppezauer, M., Galleni, M., Frère, J.-M., Rossolini, G. M., Amicosante, G., & Adolph, H. W. (2000). Kinetic and spectroscopic characterization of native and metal-substituted beta-lactamase from Aeromonas hydrophila AE036. FEBS Letters, 467 (2-3), 221-5. doi:10.1016/S0014-5793(00)01102-9 |
Rhazi, N., Galleni, M., Page, M. I., & Frère, J.-M. (15 July 1999). Peptidase Activity of Beta-Lactamases. Biochemical Journal, 341 ((Pt 2)), 409-13. doi:10.1042/0264-6021:3410409 |
Laraki, N., Galleni, M., Thamm, I., Riccio, M. L., Amicosante, G., Frère, J.-M., & Rossolini, G. M. (April 1999). Structure of In31, a Blaimp-Containing Pseudomonas Aeruginosa Integron Phyletically Related to In5, Which Carries an Unusual Array of Gene Cassettes. Antimicrobial Agents and Chemotherapy, 43 (4), 890-901. doi:10.1128/aac.43.4.890 |
Frère, J.-M., Dubus, A., Galleni, M., Matagne, A., & Amicosante, G. (February 1999). Mechanistic Diversity of Beta-Lactamases. Biochemical Society Transactions, 27 (2), 58-63. doi:10.1042/bst0270058 |
Matagne, A., Dubus, A., Galleni, M., & Frère, J.-M. (February 1999). The Beta-Lactamase Cycle: A Tale of Selective Pressure and Bacterial Ingenuity. Natural Product Reports, 16 (1), 1-19. doi:10.1039/a705983c |
Prosperi, C., Llabres, G., De Seny, D., Soto, R. P., Valladares, M. H., Laraki, N., Frère, J.-M., & Galleni, M. (25 January 1999). Interaction between Class B Beta-Lactamases and Suicide Substrates of Active-Site Serine Beta-Lactamases. FEBS Letters, 443 (2), 109-11. doi:10.1016/S0014-5793(98)01689-5 |
Damblon, C., Prosperi, C., Lian, L. Y., Barsukov, I., Soto, R. P., Galleni, M., Frère, J.-M., & Roberts, G. C. K. (1999). H-1-N-15 HMQC for the identification of metal-bound histidines in Cd-113-substituted Bacillus cereus zinc beta-lactamase. Journal of the American Chemical Society, 121 (49), 11575-11576. doi:10.1021/ja992896h |
Laraki, N., Franceschini, N., Rossolini, G. M., Santucci, P., Meunier, C., De Pauw, E., Amicosante, G., Frère, J.-M., & Galleni, M. (1999). Biochemical characterization of the Pseudomonas aeruginosa 101/1477 metallo-beta-lactamase IMP-1 produced by Escherichia coli. Antimicrobial Agents and Chemotherapy, 43 (4), 902-6. doi:10.1128/aac.43.4.902 |
Paul-Soto, R., Bauer, R., Frère, J.-M., Galleni, M., Meyer-Klaucke, W., Nolting, H., Rossolini, G. M., DE SENY, D., Hernandez-Valladares, M., Zeppezauer, M., & Adolph, H. W. (1999). Mono- and binuclear Zn2+-beta-lactamase. Role of the conserved cysteine in the catalytic mechanism. Journal of Biological Chemistry, 274 (19), 13242-9. doi:10.1074/jbc.274.19.13242 |
Paul-Soto, R., Zeppezauer, M., Adolph, H. W., Galleni, M., Frère, J.-M., Carfi, A., Dideberg, O., Wouters, J., Hemmingsen, L., & Bauer, R. (1999). Preference of Cd(II) and Zn(II) for the two metal sites in Bacillus cereus beta-lactamase II: A perturbed angular correlation of gamma-rays spectroscopic study. Biochemistry, 38 (50), 16500-6. doi:10.1021/bi9911381 |
Rossolini, G. M., Franceschini, N., Lauretti, L., Caravelli, B., Riccio, M. L., Galleni, M., Frère, J.-M., & Amicosante, G. (1999). Cloning of a Chryseobacterium (Flavobacterium) meningosepticum chromosomal gene (blaA(CME)) encoding an extended-spectrum class A beta-lactamase related to the Bacteroides cephalosporinases and the VEB-1 and PER beta-lactamases. Antimicrobial Agents and Chemotherapy, 43 (9), 2193-9. doi:10.1128/aac.43.9.2193 |
Bounaga, S., Laws, A. P., Galleni, M., & Page, M. I. (1998). The mechanism of catalysis and the inhibition of the Bacillus cereus zinc-dependent beta-lactamase. Biochemical Journal, 331 ( Pt 3), 703-11. doi:10.1042/bj3310703 |
Carfi, A., Duee, E., Paul-Soto, R., Galleni, M., Frère, J.-M., & Dideberg, O. (1998). X-ray structure of the ZnII beta-lactamase from Bacteroides fragilis in an orthorhombic crystal form. Acta Crystallographica. Section D, Biological Crystallography, 54 (Pt 1), 45-57. doi:10.1107/s090744499700927x |
Charlier, P., Coyette, J., Dehareng, D., Dive, G., Duez, C., Dusart, J., Fonzé, E., Fraipont, C., Frère, J.-M., Galleni, M., Goffin, C., Joris, B., Lamotte-Brasseur, J., & Nguyen-Distèche, M. (1998). Résistance bactérienne aux beta-lactamines. MS. Medecine Sciences, 14 (5), 544-555. doi:10.4267/10608/1092 |
Paul-Soto, R., Hernandez-Valladares, M., Galleni, M., Bauer, R., Zeppezauer, M., Frère, J.-M., & Adolph, H. W. (1998). Mono- and binuclear Zn-beta-lactamase from Bacteroides fragilis: catalytic and structural roles of the zinc ions. FEBS Letters, 438 (1-2), 137-40. doi:10.1016/S0014-5793(98)01289-7 |
Rossolini, G. M., Franceschini, N., Riccio, M. L., Mercuri, P., Perilli, M., Galleni, M., Frère, J.-M., & Amicosante, G. (1998). Characterization and sequence of the Chryseobacterium (Flavobacterium) meningosepticum carbapenemase: a new molecular class B beta-lactamase showing a broad substrate profile. Biochemical Journal, 332 ( Pt 1), 145-52. doi:10.1042/bj3320145 |
Hernandez Valladares, M., Felici, A., Weber, G., Adolph, H. W., Zeppezauer, M., Rossolini, G. M., Amicosante, G., Frère, J.-M., & Galleni, M. (23 September 1997). Zn(Ii) Dependence of the Aeromonas Hydrophila Ae036 Metallo-Beta-Lactamase Activity and Stability. Biochemistry, 36 (38), 11534-41. doi:10.1021/bi971056h |
Quinting, B., Reyrat, J. M., Monnaie, D., Amicosante, G., Pelicic, V., Gicquel, B., Frère, J.-M., & Galleni, M. (14 April 1997). Contribution of Beta-Lactamase Production to the Resistance of Mycobacteria to Beta-Lactam Antibiotics. FEBS Letters, 406 (3), 275-8. doi:10.1016/S0014-5793(97)00286-X |
Quinting, B., Galleni, M., Timm, J., Gicquel, B., Amicosante, G., & Frère, J.-M. (01 April 1997). Purification and Properties of the Mycobacterium Smegmatis Mc(2)155 Beta-Lactamase. FEMS Microbiology Letters, 149 (1), 11-5. doi:10.1016/S0378-1097(97)00041-4 |
Felici, A., Perilli, M., Franceschini, N., Rossolini, G. M., Galleni, M., Frère, J.-M., Oratore, A., & Amicosante, G. (1997). Sensitivity of Aeromonas hydrophila carbapenemase to delta3-cephems: comparative study with other metallo-beta-lactamases. Antimicrobial Agents and Chemotherapy, 41 (4), 866-8. doi:10.1128/aac.41.4.866 |
Perez-Llarena, F., Martin, J. F., Galleni, M., Coque, J. J., Fuente, J. L., Frère, J.-M., & Liras, P. (1997). The bla gene of the cephamycin cluster of Streptomyces clavuligerus encodes a class A beta-lactamase of low enzymatic activity. Journal of Bacteriology, 179 (19), 6035-40. doi:10.1128/jb.179.19.6035-6040.1997 |
Hernandez Villadares, M., Galleni, M., Frère, J.-M., Felici, A., Perilli, M., Franceschini, N., Rossolini, G. M., Oratore, A., & Amicosante, G. (1996). Overproduction and purification of the Aeromonas hydrophila CphA metallo-beta-lactamase expressed in Escherichia coli. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease, 2 (2), 253-6. doi:10.1089/mdr.1996.2.253 |
Evrard, B., MELIN, P., Galleni, M., ART, M.-C., & De Mol, P. (October 1995). Etude des beta-lactamases de 7 souches hospitalières de Klebsiella pneumoniae [Poster presentation]. Symposium National de la Société Belge de Biologie Clinique, Belgium. |
Galleni, M., Lamotte-Brasseur, J., Raquet, X., Dubus, A., Monnaie, D., Knox, J. R., & Frère, J.-M. (11 May 1995). The Enigmatic Catalytic Mechanism of Active-Site Serine Beta-Lactamases. Biochemical Pharmacology, 49 (9), 1171-8. doi:10.1016/0006-2952(94)00502-D |
Lepage, S., Lakaye, B., Galleni, M., Thamm, I., Crine, M., Groslambert, S., & Frère, J.-M. (April 1995). Saturation of Penicillin-Binding Protein 1 by Beta-Lactam Antibiotics in Growing Cells of Bacillus Licheniformis. Molecular Microbiology, 16 (2), 365-72. doi:10.1111/j.1365-2958.1995.tb02308.x |
Galleni, M., Raquet, X., Lamotte-Brasseur, J., Fonze, E., Amicosante, G., & Frère, J.-M. (February 1995). Dd-Peptidases and Beta-Lactamases: Catalytic Mechanisms and Specificities. Journal of Chemotherapy, 7 (1), 3-7. doi:10.1179/joc.1995.7.1.3 |
Carfi, A., Pares, S., Duée, E., Galleni, M., Duez, C., Frère, J.-M., & Dideberg, O. (1995). The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold. EMBO Journal, 14 (20), 4914-4921. doi:10.1002/j.1460-2075.1995.tb00174.x |
Felici, A., Perilli, M., Segatore, B., Franceschini, N., Setacci, D., Oratore, A., Stefani, S., Galleni, M., & Amicosante, G. (1995). Interactions of biapenem with active-site serine and metallo-beta-lactamases. Antimicrobial Agents and Chemotherapy, 39 (6), 1300-5. doi:10.1128/AAC.39.6.1300 |
Lepage, S., Galleni, M., Lakaye, B., Joris, B., Thamm, I., & Frère, J.-M. (1995). Kinetic properties of the Bacillus licheniformis Penicillin-binding proteins. Biochemical Journal, 309, 49-53. doi:10.1042/bj3090049 |
Matagne, A., Ledent, P., Monnaie, D., Felici, A., Jamin, M., Raquet, X., Galleni, M., Klein, D., Francois, I., & Frère, J.-M. (January 1995). Kinetic Study of Interaction between Brl 42715, Beta-Lactamases, and D-Alanyl-D-Alanine Peptidases. Antimicrobial Agents and Chemotherapy, 39 (1), 227-31. doi:10.1128/aac.39.1.227 |
Galleni, M., Franceschini, N., Quinting, B., Fattorini, L., Orefici, G., Oratore, A., Frère, J.-M., & Amicosante, G. (July 1994). Use of the Chromosomal Class a Beta-Lactamase of Mycobacterium Fortuitum D316 to Study Potentially Poor Substrates and Inhibitory Beta-Lactam Compounds. Antimicrobial Agents and Chemotherapy, 38 (7), 1608-14. doi:10.1128/AAC.38.7.1608 |
Datz, M., Joris, B., Azab, E. A., Galleni, M., Van Beeumen, J., Frère, J.-M., & Martin, H. H. (1994). A common system controls the induction of very different genes. The class-A beta-lactamase of Proteus vulgaris and the enterobacterial class-C beta-lactamase. European Journal of Biochemistry, 226 (1), 149-57. doi:10.1111/j.1432-1033.1994.tb20036.x |
Granier, B., Jamin, M., Adam, M., Galleni, M., Lakaye, B., Zorzi, W., Grandchamps, J., Wilkin, J.-M., Fraipont, C., Joris, B., Duez, C., Nguyen-Distèche, M., Coyette, J., Leyh-Bouille, M., Dusart, J., Christians, L., Frère, J.-M., & Ghuysen, J.-M. (1994). Serine-Type D-Ala-D-Ala Peptidases and Penicillin-Binding Proteins. Methods in Enzymology, 244, 249-266. doi:10.1016/0076-6879(94)44021-2 |
Joris, B., Galleni, M., Frère, J.-M., & Labia, R. (1994). Analysis of the penA gene of Pseudomonas cepacia 249. Antimicrobial Agents and Chemotherapy, 38 (2), 407-8. doi:10.1128/AAC.38.2.407 |
Lakaye, B., Damblon, C., Jamin, M., Galleni, M., Lepage, S., Joris, B., Marchand-Brynaert, J., Frydrychh, C., & Frère, J.-M. (1994). Synthesis, purification and kinetic properties of fluorescein-labelled penicillins. Biochemical Journal, 300, 141-145. doi:10.1042/bj3000141 |
Galleni, M., Lakaye, B., Lepage, S., Jamin, M., Thamm, I., Joris, B., & Frère, J.-M. (01 April 1993). A New, Highly Sensitive Method for the Detection and Quantification of Penicillin-Binding Proteins. Biochemical Journal, 291 ((Pt 1)), 19-21. doi:10.1042/bj2910019 |
Franceschini, N., Galleni, M., Frère, J.-M., Oratore, A., & Amicosante, G. (1993). A class-A beta-lactamase from Pseudomonas stutzeri that is highly active against monobactams and cefotaxime. Biochemical Journal, 292 ( Pt 3), 697-700. doi:10.1042/bj2920697 |
Adam, M., Damblon, C., Jamin, M., Zorzi, W., Dusart, V., Galleni, M., El Kharroubi, A., Piras, G., Spratt, B. G., Keck, W., Coyette, J., Ghuysen, J.-M., NGuyen-Distèche, M., & Frère, J.-M. (1991). Acyltransferase activities of the high-molecular-mass essential penicillin-binding proteins. Biochemical Journal, 279 (Part 2), 601-604. doi:10.1042/bj2790601 |
Frère, J.-M., Joris, B., Jacob, F., Matagne, A., Monnaie, D., Jamin, M., Hadonou, M., Bourguignon-Bellefroid, C., Varetto, L., Wilkin, J.-M., Dubus, A., Damblon, C., Adam, M., Ledent, P., De Meester, F., & Galleni, M. (1991). Mechanism of action of β-lactamases and DD-peptidases. In U. K. Pandit & F. C. Alderweireldt (Eds.), Bioorganic Chemistry in Healthcare and Technology (pp. 161-170). New York, United States - New York: Plenum Press. |
Galleni, M., Amicosante, G., & Frère, J.-M. (01 October 1988). A Survey of the Kinetic Parameters of Class C Beta-Lactamases. Cephalosporins and Other Beta-Lactam Compounds. Biochemical Journal, 255 (1), 123-9. doi:10.1042/bj2550123 |
Galleni, M., & Frère, J.-M. (01 October 1988). A Survey of the Kinetic Parameters of Class C Beta-Lactamases. Penicillins. Biochemical Journal, 255 (1), 119-22. doi:10.1042/bj2550119 |
Galleni, M., Lindberg, F., Normark, S., Cole, S., Honore, N., Joris, B., & Frère, J.-M. (15 March 1988). Sequence and Comparative Analysis of Three Enterobacter Cloacae Ampc Beta-Lactamase Genes and Their Products. Biochemical Journal, 250 (3), 753-60. doi:10.1042/bj2500753 |
Amicosante, G., Oratore, A., Franceschini, N., Maccarrone, M., Strom, R., Galleni, M., & Frère, J.-M. (1988). Citrobacter diversus ULA-27 beta-lactamases. Improved purification and general properties. Biochemical Journal, 254 (3), 885-90. doi:10.1042/bj2540885 |
Amicosante, G., Oratore, A., Joris, B., Galleni, M., Frère, J.-M., & Van Beeumen, J. (1988). Chromosome-encoded beta-lactamases of Citrobacter diversus. Interaction with beta-iodopenicillanate and labelling of the active site. Biochemical Journal, 254 (3), 891-3. doi:10.1042/bj2540891 |
Joris, B., De Meester, F., Galleni, M., Frère, J.-M., & Van Beeumen, J. (1987). The K1 beta-lactamase of Klebsiella pneumoniae. Biochemical Journal, 243 (2), 561-7. doi:10.1042/bj2430561 |
Joris, B., De Meester, F., Galleni, M., Masson, S., Dusart, J., Frère, J.-M., Van Beeumen, J., Bush, K., & Sykes, R. (1986). Properties of a class C beta-lactamase from Serratia marcescens. Biochemical Journal, 239 (3), 581-6. doi:10.1042/bj2390581 |
Joris, B., De Meester, F., Galleni, M., Reckinger, G., Coyette, J., Frère, J.-M., & Van Beeumen, J. (1985). The beta-lactamase of Enterobacter cloacae P99. Chemical properties, N-terminal sequence and interaction with 6 beta-halogenopenicillanates. Biochemical Journal, 228 (1), 241-8. doi:10.1042/bj2280241 |