Publications and communications of Gilles DARCIS

de Crane D'Heysselaer, S., Parisi, G., Lisson, M., Bruyère, O., Donneau, A.-F., Fontaine, S., Gillet, L., Bureau, F., Darcis, G., Thiry, E., Ducatez, M., Snoeck, C. J., Zientara, S., Haddad, N., Humblet, M.-F., Ludwig-Begall, L., Daube, G., Thiry, D., Misset, B., ... Haubruge, E. (27 February 2023). Systematic Review of the Key Factors Influencing the Indoor Airborne Spread of SARS-CoV-2. Pathogens, 12 (3), 382. doi:10.3390/pathogens12030382

Meuris, C., Darcis, G., Orban, C., Hayette, M.-P., Meex, C., Desmecht, D., & Bours, V. (2023). Study of asymptomatic rectal carriage of Monkeypox virus in men who have sex with men, and immunological answer to vaccination, followed in Liège University Hospital.

El Moussaoui, M., Desmecht, S., Tashkeev, A., Lambert, N., Maes, N., Braghini, J., MARECHAL, N., Quintana, C., BRIQUET, K., Gofflot, S., TOUSSAINT, F., Hayette, M.-P., Vermeersch, P., Lutteri, L., Grégoire, C., Beguin, Y., Rahmouni, S., Moutschen, M., Desmecht, D., & Darcis, G. (05 September 2022). Reduced T-cell response following a third dose of SARS-CoV-2 vaccine in infection-naïve people living with HIV. Journal of Infection, 85, 751-755. doi:10.1016/j.jinf.2022.09.006

Pathak, G. A., Karjalainen, J., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Andrews, S. J., Kanai, M., Cordioli, M., Polimanti, R., Harerimana, N., Pirinen, M., Liao, R. G., Chwialkowska, K., Trankiem, A., Balaconis, M. K., Nguyen, H., Solomonson, M., Veerapen, K., ... Baillie, J. K. (03 August 2022). A first update on mapping the human genetic architecture of COVID-19. Nature, 608, 1-E10. doi:10.1038/s41586-022-04826-7

Cruz, R., Almeida, S. D.-D., Heredia, M. L., Quintela, I., Ceballos, F. C., Pita, G., Lorenzo-Salazar, J. M., González-Montelongo, R., Gago-Domínguez, M., Porras, M. S., Castaño, J. A. T., Nevado, J., Aguado, J. M., Aguilar, C., Aguilera-Albesa, S., Almadana, V., Almoguera, B., Alvarez, N., Andreu-Bernabeu, Á., ... Carracedo, Á. (2022). Novel genes and sex differences in COVID-19 severity. Human Molecular Genetics. doi:10.1093/hmg/ddac132

El Moussaoui, M., Maes, N., Hong, S. L., Lambert, N., Gofflot, S., DELLOT, P., Belhadj, Y., Huynen, P., Hayette, M.-P., Meex, C., Bontems, S., Defêche, J., Godderis, L., Molenberghs, G., Meuris, C., Artesi, M., Durkin, K., Rahmouni, S., GREGOIRE, C., ... DARCIS, G. (14 June 2022). Evaluation of Screening Program and Phylogenetic Analysis of SARS-CoV-2 Infections among Hospital Healthcare Workers in Liège, Belgium. Viruses, 14 (6), 1302. doi:10.3390/v14061302

Mayasi, N., Situakibanza, H., Mbula, M., Longokolo, M., Maes, N., Bepouka, B., Ossam, J. O., MOUTSCHEN, M., & DARCIS, G. (11 March 2022). Retention in care and predictors of attrition among HIV-infected patients who started antiretroviral therapy in Kinshasa, DRC, before and after the implementation of the ‘treat-all’ strategy. PLOS Global Public Health, 2 (3), 0000259. doi:10.1371/journal.pgph.0000259

Kousathanas, A., Pairo-Castineira, E., Rawlik, K., Stuckey, A., Odhams, C. A., Walker, S., Russell, C. D., Malinauskas, T., Wu, Y., Millar, J., Shen, X., Elliott, K. S., Griffiths, F., Oosthuyzen, W., Morrice, K., Keating, S., Wang, B., Rhodes, D., Klaric, L., ... LAMBERMONT, B. (Other coll.). (2022). Whole-genome sequencing reveals host factors underlying critical COVID-19. Nature. doi:10.1038/s41586-022-04576-6

Cambier, M., Henket, M., Frix, A.-N., Gofflot, S., THYS, M., Tomasetti, S., Peired, A., Struman, I., Rousseau, A.-F., Misset, B., Darcis, G., Moutschen, M., Louis, R., Njock, M.-S., Cavalier, E., & Guiot, J. (2022). Increased KL-6 levels in moderate to severe COVID-19 infection. PLoS ONE, 17 (11), 0273107. doi:10.1371/journal.pone.0273107

Desmecht, S.* , Tashkeev, A.* , El Moussaoui, M., MARECHAL, N., Perée, H., Tokunaga, Y., Fombellida-Lopez, C., Polese, B., Legrand, C., Wéry, M., Mni, M., Fouillien, N., TOUSSAINT, F., Gillet, L., Bureau, F., LUTTERI, L., HAYETTE, M.-P., MOUTSCHEN, M., MEURIS, C., ... DARCIS, G.*. (2022). Kinetics and persistence of the cellular and humoral immune responses to BNT162b2 mRNA vaccine in SARS-CoV-2-naive and -experienced subjects: impact of booster dose and breakthrough infections. Frontiers in Immunology, 13, 863554. doi:10.3389/fimmu.2022.863554

Donneau, A.-F.* , Guillaume, M.* , BOURS, V., Dandoy, M., DARCIS, G., Desmecht, D., Diep, A. N., Fievez, L., Garigliany, M.-M., Gillain, N., Husson, E., Michel, F., MOUTSCHEN, M., Paridans, M., Pétré, B., Sabatel, C., Saegerman, C., Tytgat, A., Gillet, L.* , & Bureau, F.*. (2022). University population-based prospective cohort study of SARS-CoV- 2 infection and immunity (SARSSURV-ULiège): a study protocol. BMJ Open. doi:10.1136/bmjopen-2021-055721

Nakanishi, T., Pigazzini, S., Degenhardt, F., Cordioli, M., Butler-Laporte, G., Maya-Miles, D., Nafría-Jiménez, B., Bouysran, Y., Niemi, M., Palom, A., Ellinghaus, D., Khan, A., Martínez-Bueno, M., Rolker, S., Amitano, S., Tato, L. R., Fava, F., Spinner, C. D., Prati, D., ... consortium, C.-H. (October 2021). Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality. Journal of Clinical Investigation, Online ahead of print.. doi:10.1172/JCI152386

BOUQUEGNEAU, A., HUART, J., LUTTERI, L., ERPICUM, P., GROSCH, S., Résimont, G., WIESEN, P., ROUSSEAU, A.-F., BOVY, C., KRZESINSKI, J.-M., THYS, M., LAMBERMONT, B., Misset, B., Pottel, H., DARCIS, G., CAVALIER, E., JOURET, F., & DELANAYE, P. (2021). Survivors of COVID-19 mostly recover from tubular proteinuria and acute kidney injury after hospital discharge. Journal of Nephrology, 34 (4), 967-969. doi:10.1007/s40620-021-01075-1

Meuris, C., Kremer, C., Geerinck, A., Locquet, M., Bruyère, O., Defêche, J., Meex, C., Hayette, M.-P., Duchene, L., Dellot, P., Azarzar, S., Maréchal, N., Sauvage, A.-S., Frippiat, F., Giot, J.-B., Léonard, P., Fombellida, K., Moutschen, M., Durkin, K., ... Darcis, G. (2021). Transmission of SARS-CoV-2 After COVID-19 Screening and Mitigation Measures for Primary School Children Attending School in Liège, Belgium. JAMA Network Open, 4 (10), 2128757. doi:10.1001/jamanetworkopen.2021.28757

Ngongo, N. M., Darcis, G., Nanituna, H. S., Mambimbi, M. M., Maes, N., Mashi, M. L., Bepouka Izizag, B., Moutschen, M., & Lepira Bompeka, F. (2021). Longitudinal analysis of sociodemographic, clinical and therapeutic factors of HIV-infected individuals in Kinshasa at antiretroviral therapy initiation during 2006-2017. PLoS ONE, 16 (11), 0259073. doi:10.1371/journal.pone.0259073

Niemi, M., Gazon, H., JUSZCZAK, D., FADEUR, M., CAMBY, S., MEURIS, C., THYS, M., JACQUES, J., HENKET, M., BEGUIN, Y., Rahmouni, S., Lebrun, M., MOUTSCHEN, M., Misset, B., DARCIS, G., GUIOT, J., AZARZAR, S., DELLOT, P., GOFFLOT, S., ... HUYNEN, P. (Other coll.). (2021). Mapping the human genetic architecture of COVID-19. Nature, 600, 472-477. doi:10.1038/s41586-021-03767-x

Ait-Ammar, A., Kula, A., DARCIS, G., Verdikt, R., De wit, S., Gautier, V., Mallon, P., Marcello, A., Rohr, O., & Van Lint, C. (2020). Current Status of Latency Reversing Agents Facing the Heterogeneity of HIV-1 Cellular and Tissue Reservoirs. Frontiers in Microbiology. doi:10.3389/fmicb.2019.03060

Darcis, G., Berkhout, B., & Pasternak, A. O. (2020). Differences in HIV Markers between Infected Individuals Treated with Different ART Regimens: Implications for the Persistence of Viral Reservoirs. Viruses, 12 (5). doi:10.3390/v12050489

Darcis, G., Kootstra, N. A., Hooibrink, B., van Montfort, T., Maurer, I., Groen, K., Jurriaans, S., Bakker, M., van Lint, C., Berkhout, B., & Pasternak, A. O. (2020). CD32+CD4+ T Cells Are Highly Enriched for HIV DNA and Can Support Transcriptional Latency. Cell Reports, 30 (7), 2284-2296.e3. doi:10.1016/j.celrep.2020.01.071

DARCIS, G., VAIRA, D., & MOUTSCHEN, M. (2020). Impact of coronavirus pandemic and containment measures on HIV diagnosis. Epidemiology and Infection. doi:10.1017/S0950268820001867

Cimpaye, O., Louis, R., Darcis, G., Beaudart, C., & MEURIS, C. (2019). Evaluation de l'application des recommandations du Conseil Supérieur de la Santé relatives à l'isolement respiratoire des malades atteints de la tuberculose pulmonaire au CHU de Liège. Revue Médicale de Liège, 74 (9), 465-470.

DARCIS, G., Binda, C., Klaver, B., Herrera-Carrillo, E., Berkhout, B., & Das, A. (2019). The Impact of HIV-1 Genetic Diversity on CRISPR-Cas9 Antiviral Activity and Viral Escape. Viruses. doi:10.3390/v11030255

Van Montfort, T., Van der sluis, R., DARCIS, G., Beaty, D., Groen, K., Pasternak, A., Pollakis, G., Vink, M., Westerhout, E., Hamdi, M., Bakker, M., Van Der Putten, B., Jurriaans, S., Prins, J., Jeeninga, R., Thomas, A., Speijer, D., & Berkhout, B. (2019). Dendritic cells potently purge latent HIV-1 beyond TCR-stimulation, activating the PI3K-Akt-mTOR pathway. EBioMedicine. doi:10.1016/j.ebiom.2019.02.014

DARCIS, G., Lambert, I., SAUVAGE, A.-S., FRIPPIAT, F., MEURIS, C., UURLINGS, F., LECOMTE, M., LEONARD, P., GIOT, J.-B., fombellida, K., VAIRA, D., & MOUTSCHEN, M. (2018). Factors associated with late presentation for HIV care in a single Belgian reference center: 2006-2017. Scientific Reports. doi:10.1038/s41598-018-26852-0

DARCIS, G., Das, A. T., & Berkhout, B. (2018). Tackling HIV Persistence: Pharmacological versus CRISPR-Based Shock Strategies. Viruses. doi:10.3390/v10040157

DE VOEGHT, A., Martens, H., RENARD, J. D. C., VAIRA, D., Debruche, M., Simonet, J., Geenen, V., MOUTSCHEN, M., & DARCIS, G. (2017). Exploring the link between innate immune activation and thymic function by measuring sCD14 and TRECs in HIV patients living in Belgium. PLoS ONE. doi:10.1371/journal.pone.0185761

DARCIS, G., Van der Auwera, G., GIOT, J.-B., Hayette, M.-P., Tassin, F., Arrese Estrada, J., Cnops, L., Moutschen, M., de Leval, L., & LEONARD, P. (07 July 2017). Recurrence of visceral and muco-cutaneous leishmaniasis in a patient under immunosuppressive therapy. BMC Infectious Diseases, 17. doi:10.1186/s12879-017-2571-x

Bouchat, S., Delacourt, N., Kula, A., DARCIS, G., Van Driessche, B., Corazza, F., GATOT, J.-S., Melard, A., Vanhulle, C., Kabeya, K., Pardons, M., Avettand-Fenoel, V., Clumeck, N., De Wit, S., Rohr, O., Rouzioux, C., & Van Lint, C. (2016). Sequential treatment with 5-aza-2'-deoxycytidine and deacetylase inhibitors reactivates HIV-1. EMBO Molecular Medicine. doi:10.15252/emmm.201505557

DARCIS, G., Coombs, R. W., & Van Lint, C. (2016). Exploring the anatomical HIV reservoirs: Role of the testicular tissue. AIDS, 30 (18), 2891-2893. doi:10.1097/QAD.0000000000001281

DARCIS, G., Kula, A., Bouchat, S., Fujinaga, K., Corazza, F., Ait-Ammar, A., Delacourt, N., Melard, A., Kabeya, K., Vanhulle, C., Van Driessche, B., GATOT, J.-S., Cherrier, T., Pianowski, L. F., Gama, L., Schwartz, C., Vila, J., Burny, A., Clumeck, N., ... Van Lint, C. (2015). An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression. PLoS Pathogens, 11 (7), 1005063. doi:10.1371/journal.ppat.1005063