Publications and communications of FLorence SCHLEICH

Zahraei, H. N., Schleich, F., Louis, G., Gerday, S., SABBE, M., Bougard, N., GUISSARD, F., PAULUS, V., Henket, M., Pétré, B., Donneau, A.-F., & Louis, R. (2024). Evidence for two clusters among non-eosinophilic asthmatics. Annals of Allergy, Asthma and Immunology. doi:10.1016/j.anai.2024.03.012

Louis, F., Piccard, E., Streel, S., De Wulf, I., Saevels, J., Pétré, B., Schleich, F., & Philippe, G. (February 2024). Intégration d’une dimension écologique au sein des séances d’éducation thérapeutique chez les patients asthmatiques en pharmacie d’officine [Paper presentation]. Société d'Éducation Thérapeutique Européenne, Liège, Belgium.

Schleich, F., SABBE, M., Moermans, C., & Louis, R. (January 2024). Le médicament du mois. Tézépélumab (Tezspire®) : nouveau traitement biologique de l’asthme sévère. Revue Médicale de Liège, 79 (1), 60 - 64.

Louis, G., Schleich, F., Guillaume, M., Sousa-Pinto, B., Bousquet, J., Ganse, É. V., Louis, R., & Pétré, B. (2023). Back to the roots of medicine: It's severe asthma patient-reported symptoms that matter! Pulmonology. doi:10.1016/j.pulmoe.2023.10.005

Bossios, A., Bacon, A. M., Eger, K., Paróczai, D., Schleich, F., Hanon, S., Sergejeva, S., Zervas, E., Katsoulis, K., Aggelopoulou, C., Kostikas, K., Gaki, E., Rovina, N., Csoma, Z., Grisle, I., Bieksiené, K., Palacionyte, J., Ten Brinke, A., Hashimoto, S., ... Hyland, M. E. (November 2023). COVID-19 vaccination acceptance, safety and side-effects in European patients with severe asthma. ERJ Open Research, 9 (6). doi:10.1183/23120541.00590-2023

Schleich, F., Moermans, C., Seidel, L., Kempeneers, C., Louis, G., ROGISTER, F., Tombu, S., Pottier, L., Poirrier, A.-L., ZIANT, S., Henket, M., SANCHEZ, C., PAULUS, V., GUISSARD, F., Donneau, A.-F., & Louis, R. (November 2023). Benralizumab in severe eosinophilic asthma in real life: confirmed effectiveness and contrasted effect on sputum eosinophilia versus exhaled nitric oxide fraction - PROMISE. ERJ Open Research, 9 (6). doi:10.1183/23120541.00383-2023

Dejong, T., Hansen, M., Bertrand, V., Zanella, D., Henket, M., Massenet, T., Schleich, F., Louis, R., Focant, J.-F., & Stefanuto, P.-H. (October 2023). Une approche GC×GC-MS pour mieux comprendre les phénomènes inflammatoires au niveau moléculaire [Paper presentation]. "Coup de Jeune(s) sur la chromatographie", Lyon, France.

Papi, A., Ferreira, D. S., Agache, I., Baraldi, E., Beasley, R., Brusselle, G., Coleman, C., Gaga, M., Gotera Rivera, C. M., Melén, E., Pavord, I. D., Peñate Gómez, D., Schuermans, D., Spanevello, A., Tonia, T., & Schleich, F. (October 2023). European Respiratory Society short guidelines for the use of as-needed ICS/formoterol in mild asthma. European Respiratory Journal, 62 (4). doi:10.1183/13993003.00047-2023

Schleich, F., Maury, E., Bachert, C., Hanon, S., Michel, O., Jansen, M., Gurdain, S., Van Schoor, J., Belgian IgE (BEIgE) Study, I., Brui, G. (Other coll.), Delobbe, A. (Other coll.), de Lovinfosse, S. (Other coll.), Dobbeleir, I. (Other coll.), Dupont, L. (Other coll.), Hanon, S. (Other coll.), Maddens, S. (Other coll.), Michel, O. (Other coll.), Nowé, V. (Other coll.), Peché, R. (Other coll.), ... Vanmaele, L. (Other coll.). (October 2023). Epidemiology of sensitization to perennial aeroallergens in adults with severe asthma in Belgium. The BEIgE study. Allergy, 78 (10), 2774-2777. doi:10.1111/all.15785

Schleich, F., Moermans, C., Gerday, S., ZIANT, S., Louis, G., Bougard, N., PAULUS, V., GUISSARD, F., Henket, M., Bachert, C., & Louis, R. (October 2023). Patients With Asthma Only Sensitized to Staphylococcus aureus Enterotoxins Have More Exacerbations, Airflow Limitation, and Higher Levels of Sputum IL-5 and IgE. Journal of Allergy and Clinical Immunology: In Practice, 11 (10), 3055-3061.e4. doi:10.1016/j.jaip.2023.05.043

Bricmont, N., Bonhiver, R., Benchimol, L., Louis, B., Papon, J.-F., Monseur, J., Donneau, A.-F., Moermans, C., Schleich, F., CALMES, D., Poirrier, A.-L., Louis, R., Seghaye, M.-C., & Kempeneers, C. (18 September 2023). Temporal Stability of Ciliary Beating Post Nasal Brushing, Modulated by Storage Temperature. Diagnostics, 13 (18), 2974. doi:10.3390/diagnostics13182974

Louis, G., Schleich, F., Guillaume, M., Sousa-Pinto, B., Bousquet, J., Louis, R., & Pétré, B. (2023). How respiratory symptoms impact asthma-related quality of life in severe asthmatics. European Respiratory Journal. doi:10.1183/13993003.congress-2023.oa1526

Gerday, S., Graff, S., Moermans, C., GUISSARD, F., PAULUS, V., Henket, M., Louis, R., & Schleich, F. (2023). Super-responders to anti-IL-5/anti-IL-5R are characterised by high sputum eosinophil counts at baseline. Thorax, 2022-219781. doi:10.1136/thorax-2022-219781

Kempeneers, C., Bonhiver, R., Bricmont, N., Pirotte, M., Engelskirchen, S., Benchimol, L., CALMES, D., GUISSARD, F., Moermans, C., Seghaye, M.-C., Louis, R., & Schleich, F. (September 2023). Ciliary dyskinesia in severe asthma is not affected by chronic mucus hypersecretion. ERJ Open Research, 9 (5). doi:10.1183/23120541.00220-2023

Zahraei, H. N., Schleich, F., Gerday, S., GUISSARD, F., PAULUS, V., Henket, M., Moermans, C., Donneau, A.-F.* , & Louis, R.*. (June 2023). A clustering analysis of eosinophilic asthmatics: Two clusters with sharp differences in atopic status and disease severity. Clinical and Experimental Allergy, 53 (6), 672-678. doi:10.1111/cea.14312
* These authors have contributed equally to this work.

Louis, R., Louis, G., Bougard, N., LOUIS, S., ZIANT, S., Pétré, B., Schleich, F., Bury, T., & Delvaux, M. (May 2023). La dyspnée «sine materia». Revue Médicale de Liège, 78 (5-6), 351 - 355.

Schleich, F., Bougard, N., Moermans, C., Sabbe, M., & Louis, R. (April 2023). Cytokine-targeted therapies for asthma and COPD. European Respiratory Review: an Official Journal of the European Respiratory Society, 32 (168). doi:10.1183/16000617.0193-2022

Massenet, T., Guiot, J., Zanella, D., Dejong, T., GILTAY, L., Henket, M., GUISSARD, F., André, B., Malaise, M., Potjewijd Judith, Schleich, F., Louis, R., Focant, J.-F., & Stefanuto, P.-H. (29 March 2023). Etude métabolomique de l’air exhalé pour diagnostiquer la sclérodermie systémique par chromatographie gazeuse bidimensionnelle exhaustive [Paper presentation]. SEP 23, Paris, France.

Malaise, O., André, C., Van Durme, C., Seidel, L., Schleich, F., Louis, R., Malaise, M., & Ribbens, C. (20 March 2023). Lung Function Impairment, Associating Hyperinflation with Impaired Diffusion Capacity and Transfer Coefficient, Is a Risk Factor for Hip Osteoporosis in Patients with Chronic Obstructive Pulmonary Disease. Journal of Clinical Medicine, 12 (6), 2383. doi:10.3390/jcm12062383

Moermans, C., Brion, C., BOCK, G., Graff, S., Gerday, S., Nekoee, H., Poulet, C., Bricmont, N., Henket, M., PAULUS, V., GUISSARD, F., Louis, R., & Schleich, F. (2023). Sputum Type 2 Markers Could Predict Remission in Severe Asthma Treated With Anti-IL-5. CHEST. doi:10.1016/j.chest.2023.01.037

Louis, G., Pétré, B., Schleich, F., Zahrei, H. N., Donneau, A.-F., Henket, M., PAULUS, V., GUISSARD, F., Guillaume, M., & Louis, R. (2023). Predictors of change in asthma-related quality of life: a longitudinal real-life study in adult asthmatics. Quality of Life Research. doi:10.1007/s11136-022-03339-0

Cushen, B., Koh, M. S., Tran, T. N., Martin, N., Murray, R., Uthaman, T., Goh, C. Y. Y., Vella, R., Eleangovan, N., Bulathsinhala, L., Maspero, J. F., Peters, M. J., Schleich, F., Pitrez, P., Christoff, G., Sadatsafavi, M., Torres-Duque, C. A., Porsbjerg, C., Altraja, A., ... ISAR Inventory Study, G. (2023). Adult Severe Asthma Registries: A Global and Growing Inventory. Pragmatic and Observational Research, 14, 127-147. doi:10.2147/POR.S399879

Dejong, T., Hansen, M., Bertrand, V., Zanella, D., Henket, M., Massenet, T., Schleich, F., Louis, R., Focant, J.-F., & Stefanuto, P.-H. (2023). Volatolomic Approach to Characterise Oxidative Stress at the Molecular Level Using in vitro Models [Paper presentation]. Metabolomics 2023, Niagara Falls, Canada.

Dejong, T., Hansen, M., Bertrand, V., Zanella, D., Henket, M., Massenet, T., Schleich, F., Louis, R., Focant, J.-F., & Stefanuto, P.-H. (2023). Volatolomic approach to characterise oxidative stress at the molecular level using in vitro models [Paper presentation]. École thématique afsep vichy, Vichy, France.

Dejong, T., Hansen, M., Bertrand, V., Zanella, D., Henket, M., Massenet, T., Schleich, F., Louis, R., Focant, J.-F., & Stefanuto, P.-H. (2023). Volatolomic approach to characterise oxidative stress at the molecular level using in vitro models [Paper presentation]. SEP23, Paris, France.

Louis, G., Schleich, F., Guillaume, M., Kirkove, D., Zahrei, H., Donneau, A.-F., Henket, M., PAULUS, V., GUISSARD, F., Louis, R., & Pétré, B. (2023). Development and validation of a predictive model combining patient-reported outcome measures, spirometry and exhaled nitric oxide fraction for asthma diagnosis. ERJ Open Research, 00451-2022. doi:10.1183/23120541.00451-2022

Stefanuto, P.-H., Zanella, D., Dejong, T., Massenet, T., Di giovanni, N., GILTAY, L., Henket, M., GUISSARD, F., Schleich, F., Guiot, J., André, B., Malaise, M., Potjewijd, J., Meuwis, M.-A., Louis, E., Louis, R., & Focant, J.-F. (2023). A Journey over Current Usage of GC×GC -TOFMS in Metabolomic [Paper presentation]. GCxGC & GCTOF metabonomics Webinar.

Louis, G., Schleich, F., Louis, R., Guillaume, M., Sousa-Pinto, B., Bousquet, J., & Pétré, B. (28 December 2022). How respiratory symptoms impact asthma-related quality of life in mild asthmatics. Respiratory Medicine, 207, 107098. doi:10.1016/j.rmed.2022.107098

Zanella, D., Henket, M., Dejong, T., Schleich, F., Louis, R., Focant, J.-F., & Stefanuto, P.-H. (November 2022). Induced inflammation on in vitro lung model [Paper presentation]. Breath Biopsy Conference 2022, United Kingdom.

Kempeneers, C., Bonhiver, R., Bricmont, N., Pirotte, M., GUISSARD, F., Moermans, C., Seghaye, M.-C., Louis, R., & Schleich, F. (04 September 2022). A primary ciliary dysfunction might be present in severe asthma [Paper presentation]. ERS International Congress, Barcelone, Spain.

Gerday, S., SCHLEICH, F., Henket, M., GUISSARD, F., PAULUS, V., & LOUIS, R. (01 June 2022). Revisiting differences between atopic and non-atopic asthmatics: When age is shaping airway inflammatory profile. World Allergy Organization Journal, 15 (6), 100655. doi:10.1016/j.waojou.2022.100655

KEMPENEERS, C., Bricmont, N., Bonhiver, R., Pirotte, M., GUISSARD, F., MOERMANS, C., SEGHAYE, M.-C., LOUIS, R., & SCHLEICH, F. (18 May 2022). Ciliary dyskinesia is increased in severe asthma, but is not affected by chronic mucus hypersecretion [Poster presentation]. Congress of American Thoracic Society, San Francisco, United States - California.

Massenet, T., GUIOT, J., Zanella, D., Dejong, T., GILTAY, L., HENKET, M., GUISSARD, F., ANDRE, B., MALAISE, M., Judith Potjewijd, SCHLEICH, F., LOUIS, R., Focant, J.-F., & Stefanuto, P.-H. (18 May 2022). BREATHOMICS APPROACH TO INVESTIGATE SYSTEMIC SCLEROSIS USING THERMAL DESORPTION AND COMPREHENSIVE TWO-DIMENSIONAL GAS CHROMATOGRAPHY HIGH-RESOLUTION TIME-OF-FLIGHT MASS SPECTROMETRY [Poster presentation]. 17th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-17), Gand, Belgium.

Gerday, S., Henket, M., GUISSARD, F., PAULUS, V., Louis, R., & Schleich, F. (17 May 2022). Super responders to mepolizumab are characterized by high sputum eosinophils and FeNO at baseline [Poster presentation]. ATS International Conference, San Francisco, United States.

Louis, G., Pétré, B., SCHLEICH, F., Nekoee Zahraei, H., Donneau, A.-F., HENKET, M., PAULUS, V., GUISSARD, F., Guillaume, M., & LOUIS, R. (2022). A Real Life Longitudinal Study on Asthma-Related Quality of Life in a Secondary Care Center. American Journal of Respiratory and Critical Care Medicine. doi:10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1334

Nekoee Zahraei, H., SCHLEICH, F., HENKET, M., PAULUS, V., Gerday, S., GUISSARD, F., Donneau, A.-F., & LOUIS, R. (15 May 2022). A clustering analysis of eosinophilic asthmatics [Paper presentation]. The American Thoracic Society International Conference ATS, San Francisco, United States - California.

Schleich, F., Graff, S., Bougard, N., Frix, A.-N., Peerboom, S., Demarche, S., GUISSARD, F., PAULUS, V., Henket, M., CALMES, D., Moermans, C., & Louis, R. (May 2022). L’asthme bronchique en pratique clinique : des phénotypes inflammatoires au traitement personnalisé. Revue Médicale de Liège, 77 (5-6), 289-294.

Stefanuto, P.-H., Zanella, D., Dejong, T., Massenet, T., DiGiovanni, N., GILTAY, L., HENKET, M., GUISSARD, F., SCHLEICH, F., GUIOT, J., ANDRE, B., MALAISE, M., Potjewijd, J., MEUWIS, M.-A., LOUIS, E., & Focant, J.-F. (May 2022). Recent advances in medical applications of GC×GC [Paper presentation]. HTC-17, Ghent, Belgium.

Massenet, T., GUIOT, J., Zanella, D., Dejong, T., GILTAY, L., HENKET, M., GUISSARD, F., ANDRE, B., MALAISE, M., Potjewijd Judith, SCHLEICH, F., LOUIS, R., Focant, J.-F., & Stefanuto, P.-H. (01 February 2022). TD-GC×GC-HRTOFMS to investigate pulmonary fibrosis in patients [Poster presentation]. Multidimensional Chromatography Worshop 2022.

Bakakos, A., Schleich, F., & Bakakos, P. (2022). Biological Therapy of Severe Asthma and Nasal Polyps. Journal of Personalized Medicine, 12 (6). doi:10.3390/jpm12060976

Eger, K., Paroczai, D., Bacon, A., Schleich, F., Sergejeva, S., Bourdin, A., Vachier, I., Zervas, E., Katsoulis, K., Papapetrou, D., Kostikas, K., Csoma, Z., Heffler, E., Canonica, G. W., Grisle, I., Bieksiene, K., Palacionyte, J., Brinke, A. T., Hashimoto, S., ... Hyland, M. (2022). The effect of the COVID-19 pandemic on severe asthma care in Europe: Will care change for good? ERJ Open Research, 8 (2). doi:10.1183/23120541.00065-2022

Focant, J.-F., Stefanuto, P.-H., Zanella, D., Dejong, T., Massenet, T., Di Giovanni, N., GILTAY, L., Henket, M., GUISSARD, F., Schleich, F., Guiot, J., André, B., Malaise, M., Potjewijd, J., Meuwis, M.-A., Louis, E., & Louis, R. (2022). Exploring Volatolomes with GC×GC-TOFMS [Paper presentation]. Analytics Nantes 2022, Nantes, France.

GRAFF, S., Brusselle, G., Hanon, S., Sohy, C., Dupont, L., Peche, R., Michils, A., Pilette, C., Joos, G., Lahousse, L., Lapperre, T., LOUIS, R., & SCHLEICH, F. (2022). Anti-Interleukin-5 Therapy Is Associated with Attenuated Lung Function Decline in Severe Eosinophilic Asthma Patients From the Belgian Severe Asthma Registry. Journal of Allergy and Clinical Immunology: In Practice, 10 (2), 467-477. doi:10.1016/j.jaip.2021.09.023

Liégeois, M., Bai, Q., Fievez, L., Pirottin, D., Legrand, C., Guiot, J., Schleich, F., Corhay, J.-L., Louis, R., Marichal, T., & Bureau, F. (2022). Airway Macrophages Encompass Transcriptionally and Functionally Distinct Subsets Altered by Smoking. American Journal of Respiratory Cell and Molecular Biology, 67 (2), 241 - 252. doi:10.1165/rcmb.2021-0563OC

Louis, R., Satia, I., Ojanguren, I., Schleich, F., Bonini, M., Tonia, T., Rigau, D., Brinke, A. T., Buhl, R., Loukides, S., Kocks, J. W. H., Boulet, L.-P., Bourdin, A., Coleman, C., Needham, K., Thomas, M., Idzko, M., Papi, A., Porsbjerg, C., ... Usmani, O. S. (2022). European Respiratory Society guidelines for the diagnosis of asthma in adults. European Respiratory Journal, 60 (3). doi:10.1183/13993003.01585-2021

Moermans, C., Graff, S., Gerday, S., Schleich, F., Guiot, J., Njock, M.-S., & Louis, R. (2022). LES PROBIOTIQUES DANS LE TRAITEMENT DE L’ASTHME. Revue Médicale de Liège, 77 (5-6), 285 - 288.

Stefanuto, P.-H., Rosalba Romano, Massenet, T., SCHLEICH, F., Nandor Marczin, LOUIS, R., Jane Hill, & Focant, J.-F. (2022). Development of an analytical workflow for bronchoalveolar lavage fluids analysis using GCxGC-TOFMS [Poster presentation]. Metabolomics Society Conference, Valence, Spain.

Van Hulst, G., Jorssen, J., Jacobs, N., Henket, M., Louis, R., Schleich, F., Bureau, F., & Desmet, C. (2022). Reply: Ex vivo SOCS3 gene responsiveness to alarmins in eosinophils of mepolizumab-treated patients is as yet of unknown biological significance. European Respiratory Journal, 60 (1). doi:10.1183/13993003.00981-2022

Van Hulst, G., Jorssen, J., Jacobs, N., Henket, M., Louis, R., Schleich, F., Bureau, F., & Desmet, C. (2022). Anti-IL-5 mepolizumab minimally influences residual blood eosinophils in severe asthma. European Respiratory Journal. doi:10.1183/13993003.00935-2021

Louis, R., Bougard, N., Louis, G., Pétré, B., & Schleich, F. (October 2021). Le médicament du mois. Combinaison fixe mométasone, indacatérol, glycopyrronium pour le traitement de l’asthme sévère : Enerzair® Breezhaler®. Revue Médicale de Liège, 76 (10), 768-772.

Louis, G., SCHLEICH, F., Guillaume, M., Donneau, A.-F., Nekoee Zahraei, H., HENKET, M., PAULUS, V., GUISSARD, F., Louis, R., & Pétré, B. (05 September 2021). Are asthma symptom intensity scales better than biomarkers for diagnosing asthma? A prospective observational study [Poster presentation]. ERS International Congress 2021 (Virtual).

Louis, G., Pétré, B., SCHLEICH, F., Nekoee Zahraei, H., Donneau, A.-F., Silvestre, A., HENKET, M., PAULUS, V., GUISSARD, F., Guillaume, M., & Louis, R. (2021). Predictors of asthma-related quality of life in a large cohort of asthmatics : A cross-sectional study in a secondary care center. Clinical and Translational Allergy. doi:10.1002/clt2.12054

Zanella, D., HENKET, M., SCHLEICH, F., Dejong, T., LOUIS, R., Focant, J.-F., & Stefanuto, P.-H. (June 2021). In vitro modelling of lung inflammatory processes [Paper presentation]. 18th international GcxGC symposium.

Louis, R., & Schleich, F. (01 April 2021). Granulocytic Airway Inflammation and Clinical Asthma Outcomes. American Journal of Respiratory and Critical Care Medicine, 203 (7), 797-799. doi:10.1164/rccm.202102-0356ED

Moermans, C., Damas, K., Guiot, J., NJOCK, M.-S., Corhay, J.-L., Henket, M., Schleich, F., & Louis, R. (April 2021). Sputum IL-25, IL-33 and TSLP, IL-23 and IL-36 in airway obstructive diseases. Reduced levels of IL-36 in eosinophilic phenotype. Cytokine, 140, 155421. doi:10.1016/j.cyto.2021.155421

Zanella, D., GUIOT, J., Stefanuto, P.-H., GILTAY, L., HENKET, M., GUISSARD, F., ANDRE, B., MALAISE, M., Pojtewijd, J., SCHLEICH, F., Louis, R., & Focant, J.-F. (2021). Breathomics to diagnose systemic sclerosis using thermal desorption and comprehensive two-dimensional gas chromatography high-resolution time-of-flight mass spectrometry. Analytical and Bioanalytical Chemistry. doi:10.1007/s00216-021-03333-4

CALMES, D., Graff, S., MAES, N., Frix, A.-N., THYS, M., BONHOMME, O., Berg, J., DEBRUCHE, M., GESTER, F., HENKET, M., PAULUS, V., DUYSINX, B., HEINEN, V., NGUYEN DANG, D., PAULUS, A., QUAEDVLIEG, V., VAILLANT, F., VAN CAUWENBERGE, H., MALAISE, M., ... SCHLEICH, F. (2021). Asthma and COPD Are Not Risk Factors for ICU Stay and Death in Case of SARS-CoV2 Infection. Journal of Allergy and Clinical Immunology: In Practice, 9 (1), 160-169. doi:10.1016/j.jaip.2020.09.044

Calmes, D., Huynen, P., Paulus, V., Henket, M., Guissard, F., Moermans, C., Louis, R., & Schleich, F. (2021). Chronic infection with Chlamydia pneumoniae in asthma: a type-2 low infection related phenotype. Respiratory Research, 22 (1), 72. doi:10.1186/s12931-021-01635-w

CATALDO, D., LOUIS, R., MICHILS, A., PECHE, R., PILETTE, C., SCHLEICH, F., NINANE, V., & HANON, S. (2021). Severe asthma: oral corticosteroid alternatives and the need for optimal referral pathways. Journal of Asthma. doi:10.1080/02770903.2019.1705335

Gerday, S., SCHLEICH, F., HENKET, M., GUISSARD, F., PAULUS, V., & LOUIS, R. (2021). Asthmatics with concordant eosinophilic disease classified according to their serum IgE status. Respiratory Medicine and Research. doi:10.1016/j.resmer.2020.100797

Graff, S., Zanella, D., Stefanuto, P.-H., HENKET, M., PAULUS, V., GUISSARD, F., MOERMANS, C., Van Steen, K., Louis, R., & Schleich, F. (2021). Are Volatile Organic Compounds Able to Identify Airflow Decline in Asthma? Journal of Asthma and Allergy, 14, 67-70. doi:10.2147/JAA.S289278

Louis, R., CALMES, D., Frix, A.-N., & Schleich, F. (2021). COVID-19 et asthme. Revue Médicale de Liège, 75 (S1), 130-132.

Schleich, F., Graff, S., GUISSARD, F., HENKET, M., Paulus, V., & Louis, R. (2021). Asthma in elderly is characterized by increased sputum neutrophils, lower airway caliber variability and air trapping. Respiratory Research, 22 (1), 15. doi:10.1186/s12931-021-01619-w

Stefanuto, P.-H., Zanella, D., Joeri, V., HENKET, M., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (2021). Exhaled breath analysis using full-scan SIFT-MS data: development of chemometric approaches and clinical potential [Paper presentation]. Anatune e-seminar.

Stefanuto, P.-H., Zanella, D., Schleich, F., Joeri, V., HENKET, M., LOUIS, R., & Focant, J.-F. (2021). Développement d'une approche multimodale pour le phénotypage de l'asthme sur base d'analyse d'air exhalé [Paper presentation]. 14 ème Congrès de l'Association Francophone des Sciences Séparatives, Paris, France.

Stefanuto, P.-H., Zanella, D., Vercammen, J., HENKET, M., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (2021). Asthma phenotyping using exhaled breath analysis and full-scan SIFT-MS data [Paper presentation]. MSACL annual meeting - virtual.

van de Wetering, C., Manuel, A. M., Sharafi, M., Aboushousha, R., Qian, X., Erickson, C., MacPherson, M., Chan, G., Adcock, I. M., ZounematKermani, N., Schleich, F., Louis, R., Bohrnsen, E., D'Alessandro, A., Wouters, E. F., Reynaert, N. L., Li, J., Wolf, C. R., Henderson, C. J., ... Janssen-Heininger, Y. M. (2021). Glutathione-S-transferase P promotes glycolysis in asthma in association with oxidation of pyruvate kinase M2. Redox Biology, 47. doi:10.1016/j.redox.2021.102160

Wechsler, M. E., Munitz, A., Ackerman, S. J., Drake, M. G., Jackson, D. J., Wardlaw, A. J., Dougan, S. K., Berdnikovs, S., Schleich, F., Matucci, A., Chanez, P., Prazma, C. M., Howarth, P., Weller, P. F., & Merkel, P. A. (2021). Eosinophils in Health and Disease: A State-of-the-Art Review. Mayo Clinic Proceedings, 96 (10), 2694 - 2707. doi:10.1016/j.mayocp.2021.04.025

Zanella, D., GUIOT, J., Stefanuto, P.-H., GILTAY, L., HENKET, M., GUISSARD, F., ANDRE, B., MALAISE, M., Potjewijd, J., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (2021). TD-GC×GC-HRTOFMS for Breath Profiling of Systemic Sclerosis. In Proceedings.

Graff, S., Bricmont, N., MOERMANS, C., HENKET, M., PAULUS, V., GUISSARD, F., LOUIS, R., & SCHLEICH, F. (2020). Clinical and biological factors associated with irreversible airway obstruction in adult asthma. Respiratory Medicine. doi:10.1016/j.rmed.2020.106202

Stefanuto, P.-H., Zanella, D., Franchina, F., Henin, A., Dejong, T., SCHLEICH, F., GUIOT, J., LOUIS, R., & Focant, J.-F. (November 2020). GC×GC-HRTOFMS for untargeted screening of exhaled breath [Paper presentation]. LECO and The Analytical Scientist Webinar.

Stefanuto, P.-H., Zanella, D., SCHLEICH, F., Joeri, V., Dejong, T., HENKET, M., LOUIS, R., & Focant, J.-F. (November 2020). Translating breath-based asthma phenotyping into clinical practice [Paper presentation]. Breath Biopsy Conference (online).

van Bragt, J. J. M. H., Adcock, I. M., Bel, E. H. D., Braunstahl, G.-J., ten Brinke, A., Busby, J., Canonica, G. W., Cao, H., Chung, K. F., Csoma, Z., Dahlén, B., Davin, E., Hansen, S., Heffler, E., Horvath, I., Korn, S., Kots, M., Kuna, P., Kwon, N., ... SHARP Clinical Research Collaboration. (October 2020). Characteristics and treatment regimens across ERS SHARP severe asthma registries. European Respiratory Journal, 55 (1). doi:10.1183/13993003.01163-2019

Meys, R., Stoffels, A. A. F., de Brandt, J., van Hees, H. W. H., Franssen, F. M. E., Sillen, M. J. H., Wouters, E. F. M., Burtin, C., Klijn, P., Bij de Vaate, E., van den Borst, B., Otker, J. M., Donkers, J., Schleich, F., Hayot, M., Pomiès, P., Everaert, I., Derave, W., Spruit, M. A., & BASES consortium. (13 September 2020). Beta-alanine supplementation in patients with COPD receiving non-linear periodised exercise training or neuromuscular electrical stimulation: protocol of two randomised, double-blind, placebo-controlled trials. BMJ Open, 10 (9), 038836. doi:10.1136/bmjopen-2020-038836

Nekoee Zahraei, H., Graulich, E., SCHLEICH, F., GUISSARD, F., Paulus, V., HENKET, M., Donneau, A.-F., & Louis, R. (07 September 2020). Are T2 biomarkers of any help in asthma diagnosis? [Paper presentation]. ERS VIRTUAL CONGRESS 2020.

Graff, S., Vanwynsberghe, S., Brusselle, G., Hanon, S., Sohy, C., Dupont, L., Peche, R., Michils, A., Pilette, C., Joos, G., Louis, R., & Schleich, F. (August 2020). Chronic oral corticosteroids use and persistent eosinophilia in severe asthmatics from the Belgian severe asthma registry. Respiratory Research, 21 (1), 214. doi:10.1186/s12931-020-01460-7

Schleich, F., Malinovschi, A., CHEVREMONT, A., Seidel, L., & Louis, R. (August 2020). Risk Factors associated with frequent exacerbations in asthma. Respiratory Medicine: X, 2, 100022. doi:10.1016/j.yrmex.2020.100022

Nekoee Zahraei, H., Graulich, E., Schleich, F., GUISSARD, F., Paulus, V., HENKET, M., Donneau, A.-F., & Louis, R. (06 July 2020). Are type-2 biomarkers of any help in asthma diagnosis? [letter to the editor]. ERJ Open Research, 6. doi:10.1183/23120541.00169-2020

Zanella, D., HENKET, M., SCHLEICH, F., Dejong, T., LOUIS, R., Focant, J.-F., & Stefanuto, P.-H. (2020). Comparison of the effect of chemically and biologically induced inflammation on the volatile metabolite production of lung epithelial cells by GC⨯GC-TOFMS. Analyst. doi:10.1039/d0an00720j

Brenard, E., Pilette, C., Dahlqvist, C., Colinet, B., Schleich, F., Roufosse, F., & Froidure, A. (April 2020). Real-Life Study of Mepolizumab in Idiopathic Chronic Eosinophilic Pneumonia. Lung, 198 (2), 355-360. doi:10.1007/s00408-020-00336-3

Dupont, L., Pilette, C., Schleich, F., & Joos, G. (April 2020). Health literacy among asthma patients and treatment expectations: results of a Belgian survey. Acta Clinica Belgica, 75 (2), 141 - 148. doi:10.1080/17843286.2018.1564543

Stefanuto, P.-H., Zanella, D., SCHLEICH, F., Vercammen, J., HENKET, M., Dejong, T., Louis, R., & Focant, J.-F. (March 2020). Multimodal Approaches for Untargeted Screening for Medical Applications of the Human Volatilome [Paper presentation]. Pittcon 2020.

Louis, R., Bougard, N., GUISSARD, F., PAULUS, V., HENKET, M., & Schleich, F. (February 2020). Bronchodilation Test with Inhaled Salbutamol Versus Bronchial Methacholine Challenge to Make an Asthma Diagnosis: Do They Provide the Same Information? Journal of Allergy and Clinical Immunology: In Practice, 8 (2), 618-625.e8. doi:10.1016/j.jaip.2019.09.007

Bougard, N., Nekoee Zahraei, H., SCHLEICH, F., GUISSARD, F., PAULUS, V., Donneau, A.-F., & Louis, R. (2020). Assessment of diagnostic accuracy of lung function indices and FeNO for a positive methacholine challenge. Biochemical Pharmacology. doi:10.1016/j.bcp.2020.113981

Focant, J.-F., Zanella, D., HENKET, M., Dejong, T., SCHLEICH, F., LOUIS, R., & Stefanuto, P.-H. (January 2020). In vitro characterization of lung inflammation mechanisms [Paper presentation]. HTC-16, Ghent, Belgium.

Frix, A.-N., Schleich, F., PAULUS, V., GUISSARD, F., HENKET, M., & Louis, R. (2020). Effectiveness of omalizumab on patient reported outcomes, lung function, and inflammatory markers in severe allergic asthma. Biochemical Pharmacology, 179. doi:10.1016/j.bcp.2020.113944

Gerday, S., SCHLEICH, F., HENKET, M., GUISSARD, F., PAULUS, V., & Louis, R. (2020). Comparison of demographic, functional and inflammatory features between atopic and non atopic asthmatics. Retrospective study on a large cohort of patients [Paper presentation]. ERS 2020 Virtual Congress.

Hanon, S., Brusselle, G., Deschampheleire, M., Louis, R., Michils, A., Peché, R., Pilette, C., Rummens, P., Schuermans, D., Simonis, H., Vandenplas, O., & Schleich, F. (2020). COVID-19 and biologics in severe asthma: data from the Belgian Severe Asthma Registry. European Respiratory Journal, 56 (6), 2002857. doi:10.1183/13993003.02857-2020

Harrison, T., Canonica, G. W., Chupp, G., Lee, J., Schleich, F., Welte, T., Valero, A., Gemzoe, K., Maxwell, A., Joksaite, S., Yang, S., Howarth, P., & Van Dyke, M. K. (2020). Real-world mepolizumab in the prospective severe asthma REALITI-A study: initial analysis. European Respiratory Journal, 56 (4), 2000151. doi:10.1183/13993003.00151-2020

Lahousse, L., Bahmer, T., Cuevas-Ocaña, S., Flajolet, P., Mathioudakis, A. G., McDonnell, M., Uller, L., Schleich, F., Dortas Junior, S., Idzko, M., Singh, D., Ricciardolo, F. L. M., Adcock, I. M., Usmani, O., Spanevello, A., & Bonvini, S. J. (January 2020). ERS International Congress, Madrid, 2019: highlights from the Airway Diseases, Asthma and COPD Assembly. ERJ Open Research, 6 (1). doi:10.1183/23120541.00341-2019

Louis, G., Pétré, B., SCHLEICH, F., HENKET, M., PAULUS, V., GUISSARD, F., LOUIS, R., & Guillaume, M. (2020). Relationship between quality of life and disordered physiology and cytology in asthma : a retrospective study from a secondary care center [Poster presentation]. Virtual ERS International Congress.

Peerboom, S., Graff, S., SEIDEL, L., PAULUS, V., HENKET, M., SANCHEZ, C., GUISSARD, F., MOERMANS, C., LOUIS, R., & SCHLEICH, F. (2020). Predictors of a good response to inhaled corticosteroids in obesity-associated asthma. Biochemical Pharmacology. doi:10.1016/j.bcp.2020.113994

Schleich, F., Frix, A.-N., Paulus, V., Guissard, F., Sanchez, C., Henket, M., & Louis, R. (2020). Une décennie d’avancées dans l’asthme : l’apport des biothérapies. Revue Médicale de Liège, 75 (5-6), 350-355.

SCHLEICH, F., Graff, S., Nekoee Zahraei, H., MOERMANS, C., HENKET, M., SANCHEZ, C., PAULUS, V., GUISSARD, F., Donneau, A.-F., & Louis, R. (2020). Real-word experience with mepolizumab: Does it deliver what it has promised? Clinical and Experimental Allergy. doi:10.1111/cea.13601

Schleich, F., Kehl, F., Ziant, S., Guissard, F., Hermans, P., & Louis, R. (2020). Le yoga en vue d’améliorer le contrôle symptomatique des patients asthmatiques sévères traités par biologiques. Revue Médicale de Liège, 75 (10), 682-685.

Schleich, F., Vaia, E.-S., Pilette, C., Vandenplas, O., Halloy, J.-L., Michils, A., Peche, R., Hanon, S., Louis, R., & Michel, O. (2020). Mepolizumab for allergic bronchopulmonary aspergillosis: Report of 20 cases from the Belgian Severe Asthma Registry and review of the literature. Journal of Allergy and Clinical Immunology: In Practice, 8 (7), 2412-2413.e2. doi:10.1016/j.jaip.2020.03.023

SCHLEICH, F., Zanella, D., & Focant, J.-F. (2020). Exhaled volatile organic compounds for better asthma control: could it be a future noninvasive adherence test? European Respiratory Journal, 55, 1902112. doi:10.1183/13993003.02112-2019

Stefanuto, P.-H., Zanella, D., SCHLEICH, F., Dejong, T., HENKET, M., LOUIS, R., & Focant, J.-F. (January 2020). Optimization of untargeted screening workflow for the characterization of lung fluid samples [Paper presentation]. 16th Hyphenated Technique in Chromatography Conference, Ghent, Belgium.

Stefanuto, P.-H., Zanella, D., Schleich, F., LOUIS, R., & Focant, J.-F. (January 2020). Development of data processing workflow for GC×GC-TOFMS in metabolomics applications [Poster presentation]. Conférence Chimiométrie 2020, Liège, Belgium.

Stefanuto, P.-H., Zanella, D., Vercammen, J., HENKET, M., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (2020). Multimodal combination of Gc × Gc‐HRtofMS and Sift‐MS for asthma phenotyping using exhaled breath. Scientific Reports, 10 (1016159). doi:10.1038/s41598-020-73408-2

Stefanuto, P.-H., Zanella, D., Dejong, T., Weggler, B., Franchina, F., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (20 November 2019). GC×GC-(HR)TOFMS for Medical Applications [Paper presentation]. AFSEP meeting, Paris, France.

MALAISE, O., André Céline, SCHLEICH, F., LOUIS, R., & MALAISE, M. (November 2019). Systematic Osteoporosis Screening In Chronic Obtructive Pulmonary Disease (Study Of Correlation Between Pulmonary Functions Tests And Bone Parameters): Emphysematous Status Is Linked To Low Bone Density And Osteoporosis [Poster presentation]. American Congress of Rheumatology, 2019.

Zanella, D., HENKET, M., SCHLEICH, F., Louis, R., Focant, J.-F., & Stefanuto, P.-H. (October 2019). Multi-matrices screening for untargeted volatilomics by GC×GC-TOFMS. European Respiratory Journal. Supplement, 54, 4272. doi:10.1183/13993003.congress-2019.PA4272

MALAISE, O., André Cécile, SEIDEL, L., SCHLEICH, F., LOUIS, R., & MALAISE, O. (September 2019). Systematic osteoporosis screening in COPD patients: correlation between pulmonary function tests and bone parameters. Low BMI, active smoking and emphysematous phenotype as main risk factors for osteoporosis [Paper presentation]. Belgian Congress of Rheumatology 2019.

Stefanuto, P.-H., Zanella, D., Vercammen, J., SCHLEICH, F., Louis, R., & Focant, J.-F. (September 2019). Multimodal breath-based asthma phenotyping using GCxGC-HRTOFMS and SIFT-MS approaches [Paper presentation]. IABR Submit, Loughborough, United Kingdom.

Zanella, D., Stefanuto, P.-H., Dejong, T., Fucito, M., HENKET, M., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (September 2019). GC×GC-TOFMS for in vitro and ex vivo Characterization of Lung Inflammation Mechanisms [Paper presentation]. SBSE 2019, Paris, France.

Zanella, D., Stefanuto, P.-H., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (September 2019). Breath analysis for asthma phenotyping and beyond [Paper presentation]. BMSS 2019.

Focant, J.-F., Zanella, D., Stefanuto, P.-H., SCHLEICH, F., & LOUIS, R. (June 2019). LARGE SCALE BREATH MONITORING FOR ASTHMA PHENOTYPING [Paper presentation]. ASMS 2019, Atlanta, United States.

Graff, S., Demarche, S., HENKET, M., PAULUS, V., Louis, R., & SCHLEICH, F. (June 2019). Increase in blood eosinophils during follow-up is associated with lung function decline in adult asthma. Respiratory Medicine, 152, 60-66. doi:10.1016/j.rmed.2019.04.020

Stefanuto, P.-H., Zanella, D., dejong, T., Weggler, B., Franchina, F., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (June 2019). Medical Application: Breath Volatile Compounds in Asthma Patients [Paper presentation]. ASMS breakfact seminar, Atlanta, United States.

Stefanuto, P.-H., Zanella, D., Fucito, M., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (June 2019). DEVELOPMENT OF ADVANCED PROCESSING WORKFLOW FOR UNTARGETED VOLATILOMICS BY GC×GC-TOFMS [Paper presentation]. ASMS 2019, Atlanta, United States.

Stefanuto, P.-H., Zanella, D., Vercammen, J., SCHLEICH, F., Louis, R., & Focant, J.-F. (June 2019). GC×GC-TOFMS and SIFT-MS approaches for clinical breath-based asthma phenotyping [Paper presentation]. Metabolomics 2019, The Hague, Netherlands.

Zanella, D., Stefanuto, P.-H., SCHLEICH, F., Louis, R., & Focant, J.-F. (14 May 2019). Breath analysis for asthma phenotyping in large-scale clinical study [Paper presentation]. 43rd International Symposium on Capillary Chromatography & the 16th GCxGC Symposium, Fort Worth, Texas, United States.

Zanella, D., Dejong, T., SCHLEICH, F., HENKET, M., Louis, R., & Focant, J.-F. (13 May 2019). In vitro characterization of lung inflammation mechanisms [Poster presentation]. 43rd International Symposium on Capillary Chromatography & the 16th GCxGC Symposium, Fort Worth, Texas, United States.

Gerday, S., Schleich, F., Henket, M., GUISSARD, F., PAULUS, V., & Louis, R. (08 May 2019). Characterisation of a cohort of asthmatics with severe concordant eosinophilic disease according to their IgE status [Paper presentation]. GSK-SBP Pulmonology Award 2019.

SCHLEICH, F., & Louis, R. (2019). It needs more than just eosinophils to cause emphysema in COPD. European Respiratory Journal. doi:10.1183/13993003.00332-2019

Stefanuto, P.-H., Zanella, D., Fucito, M., SCHLEICH, F., Louis, R., & Focant, J.-F. (May 2019). Untargeted screening of lung ex vivo samples to support metabolic pathway discovery [Paper presentation]. International Symposium on Capillary Chromatography and GCxGC, Fort Worth, United States.

Zanella, D., Stefanuto, P.-H., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (26 March 2019). Phenotypage de l'asthme par volatilomique de l'haleine [Paper presentation]. 13ème congrès francophone sur les sciences séparatives et les couplages de l'AFSEP, Paris, France.

Zanella, D., Stefanuto, P.-H., Dubois, L., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (March 2019). Développement et validation d'une méthode de diganostique non-ciblée pour la caractérisation des fluides pulmonaires [Poster presentation]. 13ème congrès francophone sur les sciences séparatives et les couplages de l'AFSEP, Paris, France.

Zanella, D., Stefanuto, P.-H., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (22 January 2019). Breath volatile organic compounds to improve clinical asthma management [Paper presentation]. 10th Multidimensionnal Chromatography Workshop, Liège, Belgium.

Frix, A.-N., HEINEN, V., SCHLEICH, F., DUYSINX, B., PAULUS, V., & Louis, R. (2019). Thermoplastie bronchique dans le traitement de l’asthme sévère. Analyse rétrospective de 10 cas traités au CHU de Liège. Revue Médicale de Liège, 74 (2), 74-81.

Gerday, S., SCHLEICH, F., HENKET, M., GUISSARD, F., PAULUS, V., & Louis, R. (2019). Characterisation of a cohort of asthmatics with severe concordant eosinophilic disease according to their IgE status [Paper presentation]. ERS International Congress.

Maalioune, S., Corhay, J.-L., Delvenne, P., Louis, R., & SCHLEICH, F. (2019). Une sarcoïdose dans le décours d'une tuberculose. Existe-t-il un lien étiologique entre ces deux maladies granulomateuses ? Revue Médicale de Liège, 74 (7-8), 394-400.

MALAISE, O., André, C., SEIDEL, L., SCHLEICH, F., LOUIS, R., & Malaise, M. (2019). Intérêt du dépistage systématique par ostéodensitométrie osseuse chez des patients souffrant de bronchopneumopathie chronique obstructive (BPCO): indice de masse corporel bas, tabagisme actif et phénotype emphysémateux comme principaux facteurs de risque d’ostéoporose. Revue du Rhumatisme.

Pesesse, R., Stefanuto, P.-H., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (2019). Multimodal chemometric approach for the analysis of human exhaled breath in lung cancer patients by TD-GC ×GC-TOFMS. Journal of Chromatography. Biomedical Applications. doi:10.1016/j.jchromb.2019.01.029

SCHLEICH, F., Bikov, A., Mathioudakis, A. G., McDonnell, M., Andersson, C., Bonini, M., Uller, L., Idzko, M., Singh, D., Lopez-Campos, J. L., Bossios, A., Adcock, I. M., Usmani, O., Spanevello, A., & Bonvini, S. J. (2019). Research highlights from the 2018 European Respiratory Society International Congress: airway disease. ERJ Open Research, 5 (1). doi:10.1183/23120541.00225-2018

SCHLEICH, F., Zanella, D., Stefanuto, P.-H., Dallinga, J., HENKET, M., Wouters, E. F. M., Van Steen, K., Van Schooten, F., Focant, J.-F., & Louis, R. (2019). Exhaled Volatile Organic Compounds Are Able to Discriminate Between Neutrophilic and Eosinophilic Asthma. American Journal of Respiratory and Critical Care Medicine, 200 (4), 444-453. doi:10.1164/rccm.201811-2210OC

Sun, Q., Fang, L., Roth, M., Tang, X., Papakonstantinou, E., Zhai, W., Louis, R., Heinen, V., Schleich, F., Lu, S., Savic, S., Tamm, M., & Stolz, D. (2019). Bronchial thermoplasty decreases airway remodelling by blocking epithelium-derived heat shock protein-60 secretion and protein arginine methyltransferase-1 in fibroblasts. European Respiratory Journal, 54 (6). doi:10.1183/13993003.00300-2019

Zanella, D., Stefanuto, P.-H., SCHLEICH, F., Louis, R., & Focant, J.-F. (08 November 2018). Breath Print for Asthma Phenotyping [Paper presentation]. Breath Biopsy, Cambridge, United Kingdom.

Focant, J.-F., Zanella, D., Di Giovanni, N., Meuwis, M.-A., Louis, E., Schleich, F., Louis, R., & Stefanuto, P.-H. (June 2018). GC×GC-(HR)-TOFMS for Metabolomics and Volatilomics [Paper presentation]. High-throughput MS-based proteomics and metabolomics: from cells to clinic, Novara, Italy.

Zanella, D., Stefanuto, P.-H., Dubois, L., Pesesse, R., Schleich, F., Louis, R., & Focant, J.-F. (June 2018). Asthma phenotyping using exhaled volatile organic compounds [Poster presentation]. IABR Breath Summit 2018, Maestricht, Netherlands.

Focant, J.-F., Stefanuto, P.-H., Zanella, D., Meuwis, M.-A., Louis, E., Schleich, F., & LOUIS, R. (May 2018). CONTRIBUTION OF GC×GC-(HR) TOFMS TO MEDICAL APPLICATIONS [Poster presentation]. 42nd International Symposium on Capillary Chromatography & 15th GC×GC Symposium, Riva Del Garda, Italy.

Stefanuto, P.-H., Zanella, D., Dubois, L., Pesesse, R., Schleich, F., LOUIS, R., & Focant, J.-F. (May 2018). GC×GC-(HR)TOFMS : A KEY PLAYER IN YOUR TOOL BOX FOR MEDICAL APPLICATIONS [Paper presentation]. Leco seminar, Riva Del Garda, Italy.

Stefanuto, P.-H., Zanella, D., Dubois, L., Schleich, F., LOUIS, R., & Focant, J.-F. (May 2018). DEVELOPMENT AND VALIDATION OF A NON-TARGETED SCREENING APPROACH FOR THE CHARACTERIZATION OF LUNG FLUIDS [Poster presentation]. 42nd International Symposium on Capillary Chromatography & 15th GC×GC Symposium, Riva del Garda, Italy.

Zanella, D., Stefanuto, P.-H., Dubois, L., Pesesse, R., Schleich, F., LOUIS, R., & Focant, J.-F. (May 2018). ASTHMA PHENOTYPING USING BREATH- GC×GC-HRTOFMS [Paper presentation]. 42nd International Symposium on Capillary Chromatography & 15th GC×GC Symposium, Riva Del Garda, Italy.

Zanella, D., Stefanuto, P.-H., Dubois, L., Pesesse, R., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (March 2018). Use of exhaled volatile organic compounds to discriminate asthma phenotypes [Poster presentation]. BSMS Meeting 2018, Liege, Belgium.

CORNIA, O., Demarche, S., SCHLEICH, F., LOUIS, R., & Van Hees, T. (February 2018). Evaluation de l'apport d'une éducation thérapeutique menée par un pharmacien hospitalier sur l'inflammation bronchqiue des patients asthmatiques vus en consultation ambulatoire dans un centre hospitalier [Poster presentation]. 17ème Congrès de la Société Française de Pharmacie Clinique, Lille, France.

CORNIA, O., Demarche, S., SCHLEICH, F., Louis, R., & Van Hees, T. (February 2018). Evaluation de l'apport d'une éducation thérapeutique menée par un pharmacien hospitalier sur l'inflammation bronchique des patients asthmatiques vus en consultation ambulatoire dans un centre hospitalier [Poster presentation]. Association Francophone des Pharmaciens Hospitaliers de Belgique, Mons, Belgium.

Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., Louis, R., & Van Hees, T. (09 January 2018). Step-down of inhaled corticosteroids in non-eosinophilic asthma: A prospective trial in real life. Clinical and Experimental Allergy, 48 (5), 525-535. doi:10.1111/cea.13106

Andersson, C., Bonvini, S. J., Horvath, P., Marquez, E., Satia, I., Kirkham, P., SCHLEICH, F., Idzko, M., Gosens, R., Lopez-Campos, J. L., Bossios, A., Usmani, O., Spanevello, A., Adcock, I. M., & Mathioudakis, A. G. (January 2018). Research highlights from the 2017 ERS International Congress: airway diseases in focus. ERJ Open Research, 4 (1). doi:10.1183/23120541.00163-2017

CORNIA, O., Demarche, S., SCHLEICH, F., LOUIS, R., & Van Hees, T. (2018). Impact of a pharmacist-delivered educational intervention on fractional exhaled nitric oxide in patients with asthma. American Journal of Respiratory and Critical Care Medicine, 197, 1073.

CORNIA, O., Demarche, S., SCHLEICH, F., Louis, R., & Van Hees, T. (2018). Impact of a pharmacist-delivered educational intervention on fractional exhaled nitric oxide in patients with asthma [Poster presentation]. 2018 ATS International Conference, San Diego, United States.

Louis, R., ZIANT, S., Duchesnes, C., Giet, D., SCHLEICH, F., & Corhay, J.-L. (2018). Le concept d'exacerbation dans l'asthme et la BPCO : enquête sur les critères de prescription de corticoïdes systémiques et d'antibiotiques chez les généralistes et les pneumologues. Revue Médicale de Liège, 73 (11), 570-574.

Peerboom, S., Louis, R., & SCHLEICH, F. (2018). Le cas clinique du mois. Asthme et obésite : piège thérapeutique évitable, moyennant un suivi aguerri. Revue Médicale de Liège, 73 (3), 119-124.

Zanella, D., Pesesse, R., SCHLEICH, F., Stefanuto, P.-H., LOUIS, R., & Focant, J.-F. (January 2018). Tentative differentiation of asthma phenotypes using GC×GC-TOFMS [Paper presentation]. 9th MDC Workshop, Toronto, Canada.

GUIOT, J., Demarche, S., HENKET, M., PAULUS, V., Graff, S., SCHLEICH, F., Corhay, J.-L., Louis, R., & MOERMANS, C. (2017). Methodology for Sputum Induction and Laboratory Processing. Journal of Visualized Experiments, (130). doi:10.3791/56612

Qian, X., Aboushousha, R., van de Wetering, C., Chia, S. B., Amiel, E., Schneider, R. W., van der Velden, J. L. J., Lahue, K. G., Hoagland, D. A., Casey, D. T., Daphtary, N., Ather, J. L., Randall, M. J., Aliyeva, M., Black, K. E., Chapman, D. G., Lundblad, L. K. A., McMillan, D. H., Dixon, A. E., ... Janssen-Heininger, Y. M. W. (2017). IL-1/inhibitory kappaB kinase epsilon-induced glycolysis augment epithelial effector function and promote allergic airways disease. Journal of Allergy and Clinical Immunology. doi:10.1016/j.jaci.2017.08.043

Focant, J.-F., Pesesse, R., Dubois, L., Bertrand, V., De Pauw-Gillet, M.-C., SCHLEICH, F., LOUIS, R., & Stefanuto, P.-H. (September 2017). TD-GCxGC-HRTOFMS in biological applications  [Paper presentation]. SBSE Paris 2017, Paris, France.

Focant, J.-F., Stefanuto, P.-H., Pesesse, R., Gruber, Di Giovanni, N., SCHLEICH, F., LOUIS, R., Bertrand, V., & De Pauw-Gillet, M.-C. (September 2017). Extracting Disease-Specific Information from Complex Analytical Data Sets in Separation Science [Paper presentation]. FHI LAbAnalyze 2017, Rotterdam, Netherlands.

Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., Van Hees, T., & Louis, R. (May 2017). How to Approach Eosinophilic Versus Non-eosinophilic Asthma in Clinical Practice Using Biomarkers? [Poster presentation]. American Thoracic Society International Conference 2017, Washington DC, United States.

Pesesse, R., Stefanuto, P.-H., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (May 2017). Investigation of various data processing approaches for extracting disease-specific information from GC×GC-(HR)TOFMS breathprint data sets [Paper presentation]. 41th International Symposium on Capillary Chromatography & 14th GCxGC Symposium, Dallas, United States.

Trokart, R., Demarche, S., SCHLEICH, F., Paquot, N., & Louis, R. (May 2017). Asthme et obésité. Revue Médicale de Liège, 72 (5), 241-245.

Demarche, S., Schleich, F., HENKET, M., PAULUS, V., Van Hees, T., & Louis, R. (2017). Effectiveness of inhaled corticosteroids in real life on clinical outcomes, sputum cells and systemic inflammation in asthmatics: a retrospective cohort study in a secondary care centre. BMJ Open, 7 (11), 018186. doi:10.1136/bmjopen-2017-018186

Demarche, S., Schleich, F., PAULUS, V., HENKET, M., Van Hees, T., & Louis, R. (2017). Is it possible to claim or refute sputum eosinophils ≥ 3% in asthmatics with sufficient accuracy using biomarkers? [letter to the editor]. Respiratory Research, 18 (1), 133-139. doi:10.1186/s12931-017-0615-9

Demarche, S., SCHLEICH, F., PAULUS, V., HENKET, M., Van Hees, T., & Louis, R. (2017). Asthma Control and Sputum Eosinophils: A Longitudinal Study in Daily Practice. Journal of Allergy and Clinical Immunology: In Practice, 5 (5), 1335-1343.e5. doi:10.1016/j.jaip.2017.01.026

Mesnil, C., Raulier, S., Paulissen, G., Xiao, X., Birrell, M., Pirottin, D., Janss, T., Starkl, P., Ramery, E., HENKET, M., SCHLEICH, F., Radermecker, M., Thielemans, K., Gillet, L., Thiry, M., Belvisi, M., LOUIS, R., Desmet, C., Marichal, T., & Bureau, F. (21 October 2016). Lung resident eosinophils represent a distinct cell subset with homeostatic functions [Paper presentation]. FARAH Day 2016, Liege, Belgium.

da Silva, J., Hilzendeger, C., Moermans, C., SCHLEICH, F., HENKET, M., Kebadze, T., Mallia, P., Edwards, I. J., Johnston, S. L., & Louis, R. (2016). Raised interferon beta, type 3 interferon and interferon stimulated genes - evidence of innate immune activation in neutrophilic asthma. Clinical and Experimental Allergy. doi:10.1111/cea.12809

Manise, M., Bakayoko, B., SCHLEICH, F., Corhay, J.-L., & Louis, R. (July 2016). IgE mediated sensitisation to aeroallergens in an asthmatic cohort: relationship with inflammatory phenotypes and disease severity. International Journal of Clinical Practice, 70 (7), 596-605. doi:10.1111/ijcp.12837

Hilzendeger, C., da Silva, J., HENKET, M., SCHLEICH, F., CORHAY, J.-L., Kebadze, T., Edwards, M. R., Mallia, P., Johnston, S. L., & Louis, R. (30 June 2016). Reduced sputum expression of interferon-stimulated genes in severe COPD. International Journal of Chronic Obstructive Pulmonary Disease, 11, 1485-94. doi:10.2147/COPD.S105948

Pesesse, R., Stefanuto, P.-H., SCHLEICH, F., MEUWIS, M.-A., LOUIS, E., LOUIS, R., & Focant, J.-F. (30 May 2016). Investigation of the possible effect of sampling on human exhaled breath sample integrity [Poster presentation]. 40th International Symposium on Capillary Chromatography & 13th GC×GC Symposium, Riva Del Garda, Italy.

Maes, T., Cobos, F. A., SCHLEICH, F., Sorbello, V., HENKET, M., De Preter, K., Bracke, K. R., Conickx, G., Mesnil, C., Vandesompele, J., Lahousse, L., Bureau, F., Mestdagh, P., Joos, G. F., Ricciardolo, F. L. M., Brusselle, G. G., & LOUIS, R. (May 2016). Asthma inflammatory phenotypes show differential microRNA expression in sputum. Journal of Allergy and Clinical Immunology, 137 (5), 1433-46. doi:10.1016/j.jaci.2016.02.018

SCHLEICH, F., CORHAY, J.-L., & LOUIS, R. (May 2016). Blood eosinophil count to predict bronchial eosinophilic inflammation in COPD. European Respiratory Journal, 47 (5), 1562-4. doi:10.1183/13993003.01659-2015

Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., VAN HEES, T., & LOUIS, R. (05 April 2016). Detailed analysis of sputum and systemic inflammation in asthma phenotypes: are paucigranulocytic asthmatics really non-inflammatory? BMC Pulmonary Medicine, 16, 46. doi:10.1186/s12890-016-0208-2

SCHLEICH, F., Dallinga, J. W., HENKET, M., Wouters, E. F. M., Louis, R., & Van Schooten, F. J. (01 February 2016). Volatile organic compounds discriminate between eosinophilic and neutrophilic inflammation in vitro. Journal of Breath Research, 10 (1), 016006. doi:10.1088/1752-7155/10/1/016006

Pesesse, R., Stefanuto, P.-H., SCHLEICH, F., MEUWIS, M.-A., Louis, E., Louis, R., & Focant, J.-F. (28 January 2016). Characterization of human exhaled breath for non-invasive detection of diseases by GC×GC-TOFMS [Paper presentation]. 14th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology, Ghent, Belgium.

Mesnil, C.* , Raulier, S.* , Paulissen, G., Xiao, X., Birrell, M., Pirottin, D., Janss, T., Starkl, P., Ramery, E., HENKET, M., SCHLEICH, F., Radermecker, C., Thielemans, K., Gillet, L., Thiry, M., Belvisi, M., Louis, R., Desmet, C., Marichal, T.* , & Bureau, F.*. (2016). Lung-resident eosinophils represent a distinct regulatory eosinophil subset. Journal of Clinical Investigation, 126 (9), 3275-3295. doi:10.1172/JCI85664
* These authors have contributed equally to this work.

Schleich, F., Demarche, S., & Louis, R. (2016). Biomarkers in the Management of Difficult Asthma. Current Topics in Medicinal Chemistry, 16 (14), 1561-73. doi:10.2174/1568026616666151015093406

Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., Van Hees, T., & Louis, R. (27 September 2015). Asthma Control and Sputum Eosinophils: a Longitudinal Study in Daily Practice [Poster presentation]. ERS Amsterdam 2015 International Congress, Amsterdam, Netherlands.

Pesesse, R., Stefanuto, P.-H., SCHLEICH, F., Louis, R., & Focant, J.-F. (September 2015). GC×GC-TOFMS for reliable detection of candidate biomarkers in breath analyses [Paper presentation]. IABR breath summit 2015.

Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., Van Hees, T., & Louis, R. (12 June 2015). Asthma Control and Sputum Eosinophils: a Longitudinal Study in Daily Practice [Paper presentation]. AIRe WAY II, 3th annual scientific meeting.

Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., VAN HEES, T., & LOUIS, R. (02 June 2015). Asthma Control and Sputum Eosinophils: a Longitudinal Study in Daily Practice [Poster presentation]. Biomedica Summit 2015.

Pesesse, R., Stefanuto, P.-H., SCHLEICH, F., Louis, R., & Focant, J.-F. (June 2015). Screening for Putative Biomarkers of Lung Cancer in Exhaled Air [Poster presentation]. Biomedica Life Sciences Summit 2015, Genk, Belgium.

Turner, A. M., Tamasi, L., SCHLEICH, F., Hoxha, M., Horvath, I., Louis, R., & Barnes, N. (June 2015). Clinically relevant subgroups in COPD and asthma. European Respiratory Review, 24 (136), 283-98. doi:10.1183/16000617.00009014

LOUIS, R., Demarche, S., Van Hees, T., & SCHLEICH, F. (May 2015). Traitement personnalisé dans l'asthme : le cas des anticorps monoclonaux dirigés contre l'interleukine-5. Revue Médicale de Liège, 70 (5-6), 306-9.

Stefanuto, P.-H., Pesesse, R., SCHLEICH, F., De Pauw-Gillet, M.-C., LOUIS, R., & Focant, J.-F. (May 2015). In vitro and in vivo volatile fingerprinting of lung cancer [Paper presentation]. International Symposium on Capillary Chromatography and GCxGC symposium, Fort Worth, United States.

LOUIS, R., Demarche, S., & SCHLEICH, F. (2015). Les corticoïdes inhalés sont-ils suffisants pour traiter l'asthme? Perspective historique. Vaisseaux, Coeur, Poumons, 20 (4), 66-68.

Louis, R., Demarche, S., & Schleich, F. (2015). A historical perspective: Are inhaled corticoids sufficient to control asthma? Journal of Translational Internal Medicine, 3 (3), 113-115. doi:10.1515/jtim-2015-0014

Nguyen, M.-S., NGUYEN DANG, D., SCHLEICH, F., Manise, M., CORHAY, J.-L., & LOUIS, R. (2015). Etude du phénotype mixte BPCO-asthme dans une série de patients BPCO en état stable. Revue Médicale de Liège, 70 (1), 37-43.

WARNIER, H., Schleich, F., PAULUS, V., & Louis, R. (2015). Analyse des facteurs associés à la réversibilité au salbutamol dans une cohorte de patients asthmatiques en pratique clinique. Revue des Maladies Respiratoires.

SCHLEICH, F. (2014). Diagnosis and clinical interest of asthma inflammatory phenotypes [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/177575

SCHLEICH, F., Brusselle, G., Louis, R., Vandenplas, O., Michils, A., Pilette, C., Peche, R., Manise, M., & Joos, G. (December 2014). Heterogeneity of phenotypes in severe asthmatics. The Belgian Severe Asthma Registry (BSAR). Respiratory Medicine, 108 (12), 1723-32. doi:10.1016/j.rmed.2014.10.007

HEINEN, V., SCHLEICH, F., DUYSINX, B., KIRSCH, M., & LOUIS, R. (27 August 2014). Thermoplastie bronchique : une réelle avancée dans le traitement de l'asthme. Revue Médicale Suisse, 10 (439), 1544-1548.

Corhay, J.-L., SCHLEICH, F., & Louis, R. (July 2014). Phenotypes de la broncho-pneumopathie chronique obstructive. Revue Médicale de Liège, 69 (7-8), 415-21.

Pesesse, R., Stefanuto, P.-H., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (23 May 2014). Exhaled Air Analysis for Early Detection of Lung Cancer [Poster presentation]. ISCC 2014, Riva Del Garda, Italy.

SCHLEICH, F., Chevremont, A., PAULUS, V., HENKET, M., Manise, M., Seidel, L., & Louis, R. (2014). Importance of concomitant local and systemic eosinophilia in uncontrolled asthma. European Respiratory Journal, 44, 97-108. doi:10.1183/09031936.00201813

SCHLEICH, F., & LOUIS, R. (2014). Importance of concomitant local and systemic eosinophilia in uncontrolled asthma - Letter from the authors to editor. European Respiratory Journal, 44 (4), 1098-9. doi:10.1183/09031936.00118014

SCHLEICH, F., & LOUIS, R. (2014). Asthme bronchique non contrôlé : importance des phénotypes et de l'inflammation eosinophilique locale et systémique. Revue Médicale de Liège, 69 Spec No, 62-5.

Manise, M., Holtappels, G., Van Crombruggen, K., SCHLEICH, F., Bachert, C., & LOUIS, R. (2013). Sputum IgE and Cytokines in Asthma: Relationship with Sputum Cellular Profile. PLoS ONE, 8 (3), 58388. doi:10.1371/journal.pone.0058388

SCHLEICH, F., Manise, M., Sele, J., HENKET, M., Seidel, L., & LOUIS, R. (2013). Distribution of sputum cellular phenotype in a large asthma cohort: predicting factors for eosinophilic vs neutrophilic inflammation. BMC Pulmonary Medicine, 13 (1), 11. doi:10.1186/1471-2466-13-11

LOUIS, R., SCHLEICH, F., & Barnes, P. J. (2012). Corticosteroids: still at the frontline in asthma treatment? Clinics in Chest Medicine, 33 (3), 531-41. doi:10.1016/j.ccm.2012.05.004

LOUIS, R., SCHLEICH, F., Corhay, J.-L., & Louis, E. (2012). L'asthme: une maladie complexe mettant en jeu facteurs environnementaux et terrain genetique. Revue Médicale de Liège, 67 (5-6), 286-91.

MANISE, M., SCHLEICH, F., QUAEDVLIEG, V., Moermans, C., HENKET, M., SELE, J., CORHAY, J.-L., & LOUIS, R. (2012). Disturbed Cytokine Production at the Systemic Level in Difficult-to-Control Atopic Asthma: Evidence for Raised Interleukin-4 and Decreased Interferon-gamma Release following Lipopolysaccharide Stimulation. International Archives of Allergy and Immunology, 158 (1), 1-8. doi:10.1159/000329858

SCHLEICH, F., ASANDEI, R., Manise, M., SELE, J., Seidel, L., & LOUIS, R. (2012). Is FE(NO50) useful diagnostic tool in suspected asthma? International Journal of Clinical Practice, 66 (2), 158-65. doi:10.1111/j.1742-1241.2011.02840.x

SCHLEICH, F., & LOUIS, R. (2012). Les traitements cibles dans l'asthme: confirmations, espoirs et deceptions. Revue Médicale de Liège, 67 Spec No, 14-21.

SCHLEICH, F., & LOUIS, R. (2012). Intérêt de la mesure de l'inflammation en clinique dans l'asthme. In EMC Pneumologie. Paris, France: Elsevier Masson SAS. doi:10.1016/S1155-195X(12)60032-2

Bakakos, P., SCHLEICH, F., Alchanatis, M., & Louis, R. (2011). Induced sputum in asthma: from bench to bedside. Current Medicinal Chemistry, 18 (10), 1415-22. doi:10.2174/092986711795328337

LOUIS, R., GODINAS, L., & SCHLEICH, F. (2011). Induced sputum - Towards Normal Values. In S. Loukides, K. Kostikas, ... P. J. Barnes (Eds.), Non invasive assessment of airways inflammation in asthma and COPD (pp. 113-124). Athens, Greece: Paschalidis Medical Publication.

Louis, R., Manise, M., & Schleich, F. (2011). Quand l'asthme est difficile et que ce n'est pas de l'asthme: faire le diagnostic positif est-il une gageure? In L'asthme difficile. Questions pratiques (pp. 29-32). Université de Liège.

Louis, R., Manise, M., Sele, J., & Schleich, F. (2010). Inertie et observance therapeutiques en tant que facteurs influencant le controle de l'asthme. Revue Médicale de Liège, 65 (5-6), 338-42.

Manise, M., Schleich, F., Gusbin, N., Godinas, L., Henket, M., Antoine, N., Corhay, J.-L., & Louis, R. (2010). Cytokine production from sputum cells and blood leukocytes in asthmatics according to disease severity. Allergy, 65 (7), 889-96. doi:10.1111/j.1398-9995.2009.02296.x

Schleich, F., Seidel, L., Sele, J., Manise, M., Quaedvlieg, V., Michils, A., & Louis, R. (2010). Exhaled nitric oxide thresholds associated with a sputum eosinophil count >=3% in a cohort of unselected patients with asthma. Thorax, 65 (12), 1039-1044. doi:10.1136/thx.2009.124925

Louis, R., & Schleich, F. (2009). La vignette therapeutique de l'etudiant. Quand l'asthme se revele. Revue Médicale de Liège, 64 (9), 474-8.

Mievis, C., Jansen, N., Schleich, F., Gennigens, C., Rorive, A., Jerusalem, G., Fillet, G., & Sautois, B. (2009). Le cas clinique du mois. Reaction de rappel d'irradiation induite par l'administration de cyclophosphamide. Revue Médicale de Liège, 64 (4), 179-81.

Schleich, F., Manise, M., & Louis, R. (2009). L'omalizumab (Xolair) dans le traitement de l'asthme allergique persistant severe. Revue Médicale de Liège, 64 (5-6), 313-7.

SCHLEICH, F., Krzesinski, J.-M., Pierard, L., & Scheen, A. (2008). Comment je traite ... en optimisant le blocage du système rénine-angiotensine-aldostérone. Revue Médicale de Liège, 63, 174-181.

Schleich, F., Bustin, F., Bosquee, L., & Legros, J.-J. (September 2005). Diabete insipide dans le cadre d'un carcinome pulmonaire a petites cellules: un paradoxe? Annales d'Endocrinologie, 66 (4), 355-60. doi:10.1016/S0003-4266(05)81793-7

Schleich, F. (Ed.). (2005). The endocrine system. Understanding the aging process: from the cellular to the functions. FIAPA.

Schleich, F., Van Damme, H., Creemers, E., & Limet, R. (January 2005). Le cas clinique du mois. Revascularisation des artères fémorales à partir de l'aorte thoracique descendante après thrombose d'un pontage axillo-bifémoral. Revue Médicale de Liège, 60 (1), 11-7.

Schleich, F., Krzesinski, J.-M., & Legros, J.-J. (November 2004). Comment j'explore... un syndrome polyuropolydipsique insipide. Revue Médicale de Liège, 59 (11), 664-668.

Schleich, F. (October 2004). Effects of androgen substitution on lipid profile in the adult and aging hypogonadal male. European Journal of Endocrinology, 151 (4), 415 - 424. doi:10.1530/eje.0.1510415

Tancredi, A., Reginster, J.-Y., Schleich, F., Pire, G., Maassen, P., Luyckx, F., & Legros, J.-J. (September 2004). Interest of the androgen deficiency in aging males (ADAM) questionnaire for the identification of hypogonadism in elderly community-dwelling male volunteers. European Journal of Endocrinology, 151 (3), 355-360. doi:10.1530/eje.0.1510355

Schleich, F. (November 2003). Effets du traitement de substitution androgénique sur le profil lipidique de l'homme hypogonadique. Revue Médicale de Liège, 58 (11), 681 - 689.