Publications and communications of Lecomte, Frédéric

Jambo, H., Dispas, A., Hubert, C., Lecomte, F., Ziemons, E., & Hubert, P. (2022). Generic SFC-MS methodology for the quality control of vitamin D3 oily formulations. Journal of Pharmaceutical and Biomedical Analysis. doi:10.1016/j.jpba.2021.114492

Lecomte, F. (2020). Préparation d’échantillons biologiques à l’aide de supports polymériques à empreintes moléculaires (MIPs) : développement et évaluation des performances quantitatives. Unpublished doctoral thesis, ULiège - Université de Liège, Liège, Belgium.
Jury: Hubert, P. (Promotor), CHIAP, P. (Promotor), CHARLIER, C., Hantson, A.-L., Rudaz, S., Boulanger, B., & Hubert, C.

Lecomte, F.* , Aerts, J.* , Plenevaux, A., Defraiteur, C., Chappuis-Hugon, F., Rozet, E., CHIAP, P., Luxen, A., Pichon, V., Hubert, P.* , & Hubert, C.*. (20 February 2020). Performance evaluation of a MIP for the MISPE-LC determination of p-[18F]MPPF and a potential metabolite in human plasma. Journal of Pharmaceutical and Biomedical Analysis, 180. doi:10.1016/j.jpba.2019.113015

Dispas, A., Mbinze Kindenge, J., Lecomte, F., Marini Djang'Eing'A, R., & Hubert, P. (2015). Qualification de l'équipement. (ULiège - Université de Liège, PHIN2023-1 Analyse des médicaments - Méthodes d'analyse pharmaceutique et biopharmaceutique partim a : validation et qualification de l'appareillage).

Renard, J.-F., Lecomte, F., Hubert, P., de Leval, X., & Pirotte, B. (2014). N-(3-Arylaminopyridin-4-yl)alkanesulfonamides as pyridine analogs of nimesulide: Cyclooxygenases inhibition, anti-inflammatory studies and insight on metabolism. European Journal of Medicinal Chemistry, 74, 12-22. doi:10.1016/j.ejmech.2013.12.033

Lahbib, A., Lecomte, F., Ghodbane, S., Hubert, P., Sakly, M., & Abdelmelek, H. (2013). Static Magnetic Field Induced Hypovitaminosis D in Rat. Journal of Veterinary Medical Science, 75 (9), 1181-1185. doi:10.1292/jvms.13-0105

Nistor, I., Lebrun, P., Ceccato, A., Lecomte, F., Slama, I., Oprean, R., Badarau, E., Dufour, F., Dossou, K. S. S., Fillet, M., Liégeois, J.-F., Hubert, P., & Rozet, E. (2013). Implementation of a Design Space Approach for Enantiomeric Separations in Polar Organic Solvent Chromatography. Journal of Pharmaceutical and Biomedical Analysis, 74, 273-283. doi:10.1016/j.jpba.2012.10.015

Renard, J.-F., Lecomte, F., Arslan, D., Hubert, P., & Pirotte, B. (May 2012). Evaluation de l'impact au niveau pharmacocinétique de modulations structurales de N-(pyrid-4-yl)alcanesulfonamides. Poster session presented at 26èmes Journées franco-belges de pharmacochimie, Orléans, France.

Lecomte, F., Hubert, C., Demarche, S., De Bleye, C., Dispas, A., Jost, M., Frankenne, F., Ceccato, A., Rozet, E., & Hubert, P. (05 January 2012). Comparison of the quantitative performances and measurement uncertainty estimates obtained during method validation versus routine applications of a novel hydrophilic interaction chromatography method for the determination of cidofovir in human plasma. Journal of Pharmaceutical and Biomedical Analysis, 57, 153-165. doi:10.1016/j.jpba.2011.08.040

Houbart, V., COBRAIVILLE, G., Lecomte, F., Debrus, B., Hubert, P., & Fillet, M. (16 December 2011). Development of a nano-liquid chromatography on chip tandem mass spectrometry method for high-sensitivity hepcidin quantitation. Journal of Chromatography. A, 1218 (50), 9046-9054. doi:10.1016/j.chroma.2011.10.030

Houbart, V., Lecomte, F., COBRAIVILLE, G., Servais, A.-C., Hubert, P., & Fillet, M. (20 June 2011). Development and Prevalidation of a Nano-LC-Chip-MS/MS Method for High Sensitivity Hepcidin Quantitation. Poster session presented at 36th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Budapest, Hungary.

Gillet, A., Lecomte, F., Hubert, P., Compère, P., Evrard, B., & Piel, G. (14 June 2011). Topical application of liposomes: parameters influencing their effectiveness. Poster session presented at PharmSciFair, Prague, Czechia.

Gillet, A., Compère, P., Lecomte, F., Hubert, P., Ducat, E., Evrard, B., & Piel, G. (June 2011). Liposome surface charge influence on skin penetration behaviour. International Journal of Pharmaceutics, 411 (1-2), 223-231. doi:10.1016/j.ijpharm.2011.03.049

Jost, M., Frankenne, F., Maillard, C., Hubert, P., Herman, L., Delvenne, P., Piette, M., Coia, I., Evrard, B., Lecomte, F., Hubert, P., Englert, Y., Bossens, M., van Pachterbeke, C., GOFFIN, F., Doyen, J., Kridelka, F., Snoeck, R., & FOIDART, J.-M. (20 May 2011). From the Clinics to the Bench and back to the Clinics: design of a medical treatment for Cervical Intraepithelial Neoplasia (CIN). Paper presented at GIGA-Cancer Day, Liège, Belgium.

Gillet, A., Lecomte, F., Hubert, P., Compère, P., Evrard, B., & Piel, G. (12 May 2011). Parameters influencing the skin penetration effectiveness of liposomes. Paper presented at 15th Forum of Pharmaceutical Sciences, Spa, Belgium.

Renard, J.-F., Lecomte, F., de Leval, X., Hubert, P., & Pirotte, B. (May 2011). Conception, synthèse et évaluation pharmacologique de N-(pyridin-4-yl)alcanesulfonamides en tant qu'inhibiteurs de cyclooxygénases. Poster session presented at XVèmes Journées Franco-belges de pharmacochimie, Liège, Belgium.

Gillet, A., Lecomte, F., Hubert, P., Compère, P., Evrard, B., & Piel, G. (28 March 2011). Evaluation of parameters affecting skin penetration behaviour of liposomes. Poster session presented at Skin Forum 12th Annual Meeting, Frankfurt, Germany.

Debrus, B., Lebrun, P., Mbinze Kindenge, J., Lecomte, F., Ceccato, A., Caliaro, G., Mavar Tayey Mbay, J., Boulanger, B., Marini Djang'Eing'A, R., Rozet, E., & Hubert, P. (2011). Innovative high-performance liquid chromatography method development for the screening of 19 antimalarial drugs based on a generic approach, using design of experiments, independent component analysis and design space. Journal of Chromatography. A, 1218, 5205-5215. doi:10.1016/j.chroma.2011.05.102

Gillet, A., Lecomte, F., Hubert, P., Ducat, E., Evrard, B., & Piel, G. (2011). Skin penetration behaviour of liposomes as a function of their composition. European Journal of Pharmaceutics and Biopharmaceutics, 79, 43-53. doi:10.1016/j.ejpb.2011.01.011

Nistor, I., Cao, M., Debrus, B., Lebrun, P., Lecomte, F., Rozet, E., Angenot, L., Frederich, M., Oprean, R., & Hubert, P. (2011). Application of a new optimization strategy for the separation of tertiary alkaloids extracted from Strychnos usambarensis leaves. Journal of Pharmaceutical and Biomedical Analysis, 56, 30-37. doi:10.1016/j.jpba.2011.04.027

Nistor, I., Lebrun, P., Ceccato, A., Lecomte, F., Slama, I., Rozet, E., Oprean, R., Badarau, E., Dufour, F., Liégeois, J.-F., & Hubert, P. (2011). Implementation of a design space approach for enatiomeric separations in polar organic solvent chromatography. Poster session presented at 36th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, Budapest, Hungary.

Renard, J.-F., Lecomte, F., de Leval, X., Hubert, P., & Pirotte, B. (January 2011). Pyridine Derivatives of Nimesulide as New Promising Anti-inflammatory Agents. Poster session presented at Giga Days, Liège, Belgium.

Gillet, A., Lecomte, F., Hubert, P., Evrard, B., & Piel, G. (October 2010). Interest of vesicular systems in dermal drug delivery. Poster session presented at 2nd Innovation in Drug Delivery, Aix-en-Provence, France.

Houbart, V., Lecomte, F., Cobraiville, G., Crommen, J., Hubert, P., & Fillet, M. (September 2010). A LC-chip nanoelectrospray MS/MS method for hepcidin quantitation in human plasma. Poster session presented at 9th International Symposium on Drug Analysis - 22nd International Symposium on Pharmaceutical and Biomedical Analysis, Antwerp, Belgium.

Lecomte, F., Jasselette, C., Hubert, C., Demarche, S., De Bleye, C., Ceccato, A., Rozet, E., & Hubert, P. (September 2010). Validation of a HILIC method for the determination of cidofovir in plasma. Poster session presented at Drug Analysis 2010 - International Symposium on Drug Analysis, Antwerp, Belgium.

Nistor, I., Debrus, B., Lebrun, P., Lecomte, F., Cao, M., Frederich, M., Angenot, L., Boulanger, B., Oprean, R., & Hubert, P. (September 2010). Application of experimental design and design for the separation of compounds extracted from the leaves of Strychnos Usambarensis. Poster session presented at Drug analysis 2010, Antwerpen, Belgium.

Nistor, I., Lecomte, F., Mbinze Kindenge, J., Debrus, B., Lebrun, P., Marini Djang'Eing'A, R., Oprean, R., & Hubert, P. (September 2010). Transfer of a conventional LC method for the screening of conterfeit antimalarial medicines to UHPLC. Poster session presented at Drug analysis 2010, Antwerpen, Belgium.

Gillet, A., Lecomte, F., Hubert, P., Evrard, B., & Piel, G. (06 July 2010). Penetration mechanism of classical and deformable liposomes through pig ear skin. Poster session presented at Skin Forum 11th Annual Meeting, Edinburgh, United Kingdom.

Ducat, E., Brion, M., Lecomte, F., Evrard, B., & Piel, G. (June 2010). The experimental design as practical approach to develop and optimize a formulation of peptide-loaded liposomes. AAPS PharmSci, 11 (2), 966-975. doi:10.1208/s12249-010-9463-3

Renard, J.-F., Lecomte, F., de Leval, X., Hubert, P., & Pirotte, B. (21 May 2010). Nouveaux agents anti-inflammatoires en série N-(4-pyridyl)alcanesulfonamide. Paper presented at 24èmes JOURNEES FRANCO-BELGES DE PHARMACOCHIMIE, Woluwé-Saint-Lambert, Belgium.

Gillet, A., Lecomte, F., Rozet, E., Hubert, P., Evrard, B., & Piel, G. (09 April 2010). Suggested mechanism of action of classical and deformable liposomes through pig ear skin. Paper presented at Perspectives in Percutaneous Penetration 2010 12th International Conference, La Grande Motte, France.

Gillet, A., Lecomte, F., Rozet, E., Hubert, P., Evrard, B., & Piel, G. (29 March 2010). Classical and deformable liposomes: possible mechanism of penetration through pig ear skin. Poster session presented at 8th International Conference and Workshop on Biological Barriers, Saarbrücken, Germany.

Hubert, C., Houari, S., Lecomte, F., Houbart, V., De Bleye, C., Fillet, M., Piel, G., Rozet, E., & Hubert, P. (26 January 2010). Développement et validation d'une méthode de dosage de la glucosamine par SPE/LC/MS dans le plamsa canin. Paper presented at Forum des jeunes chercheurs du C.I.R.M, Liège, Belgium.

Lecomte, F., Hubert, C., Rozet, E., & Hubert, P. (26 January 2010). Intérêt de la chromatographie en mode HILIC pour le dosage du cidofovir dans des fluides biologiques. Paper presented at Forum des jeunes chercheurs du CIRM - 26 janvier 2010 - ULg, Liège, Belgium.

Nistor, I., Debrus, B., Lebrun, P., Lecomte, F., Martine, C., Frederich, M., Angenot, L., Boulanger, B., Oprean, R., & Hubert, P. (26 January 2010). Optimisation de la séparation des alcaloïdes extraits des feuilles de Strychnos usambarensis au moyen du design space. Paper presented at Assemblée générale du CIRM et forum des jeunes chercheurs, Liège, Belgium.

Gillet, A., Lecomte, F., Rozet, E., Hubert, P., Evrard, B., & Piel, G. (2010). Suggested mechanism of action of classical and deformable liposomes through pig ear skin. Journal of Pharmacy and Pharmacology, 62 (6), 788-807.

Hubert, C., Houari, S., Lecomte, F., Houbart, V., De Bleye, C., Fillet, M., Piel, G., Rozet, E., & Hubert, P. (2010). Development and validation of a sensitive solid phase extraction/hydrophilic interaction liquid chromatography/mass spectrometry method for the accurate determination of glucosamine in dog plasma. Journal of Chromatography. A, 1217, 3275-3281. doi:10.1016/j.chroma.2010.01.024

Hubert, C., Houari, S., Lecomte, F., Houbart, V., De Bleye, C., Fillet, M., Piel, G., Rozet, E., & Hubert, P. (01 December 2009). Développement et validation d'une méthode de dosage de la glucosamine par SPE/HILIC/MS dans le plamsa de chien. Poster session presented at 8ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages, Marseille, France.

Lecomte, F., Demarche, S., Evrard, S., Delaunay, S., Hubert, C., Rozet, E., & Hubert, P. (01 December 2009). Intérêt de la chromatographie liquide d'interactions hydrophiles pour l'analyse de composés polaires dans des matrices complexes. Paper presented at 8ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages - SEP09, Marseille, France.

Mbinze Kindenge, J., Marini Djang'Eing'A, R., Debrus, B., Lebrun, P., Lecomte, F., Boulanger, B., & Hubert, P. (December 2009). Développement d’une méthode pour la séparation de 19 antipaludéens par HPLC au moyen de la planification expérimentale et du Design Space. Poster session presented at 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages (SEP'09), Marseille, France.

Nistor, I., Debrus, B., Lebrun, P., Lecomte, F., Cao, M., Frederich, M., Angenot, L., Boulanger, B., Oprean, R., & Hubert, P. (December 2009). Application de la planification expérimentale et du design space pour la séparation des composés extraits des feuilles de Strychnos usambarensis. Poster session presented at 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages (SEP'09), Marseille, France.

Gillet, A., Lecomte, F., Rozet, E., Hubert, P., Evrard, B., & Piel, G. (09 June 2009). Betamethasone in cyclodextrin in deformable liposomes for dermal applications: ex vivo diffusion studies. Paper presented at PharmSciFair, Nice, France.

Gillet, A., Lecomte, F., Rozet, E., Hubert, P., Evrard, B., & Piel, G. (07 June 2009). Betamethasone in cyclodextrin in deformable liposomes for dermal applications: ex vivo diffusion studies. Poster session presented at PharmSciFair, Nice, France.

Gillet, A., Grammenos, A., Lecomte, F., Rozet, E., Hubert, P., Evrard, B., & Piel, G. (14 May 2009). Betamethasone in cyclodextrin in deformable liposomes for cutaneous applications: development and diffusion studies. Paper presented at Quatorzième Forum des Sciences Pharmaceutiques, Blankenberge, Belgium.

Gillet, A., Lecomte, F., Rozet, E., Hubert, P., Evrard, B., & Piel, G. (01 April 2009). Betamethasone in cyclodextrin in deformable liposomes for topical applications: absorption studies using pig skin. Poster session presented at Biomedica, Liège, Belgium.

Gillet, A., Lecomte, F., Rozet, E., Hubert, P., Evrard, B., & Piel, G. (09 March 2009). development and validation of a SPE-LC-UV method for the determination of betamethasone in pig skin. Poster session presented at Skin and Formulation 3rd Symposium and Skin Forum 10th Annual Meeting, Versailles, France.

Zalfen, A., Nizet, D., Jérôme, C., Jérôme, R., frankenne, F., Foidart, J.-M., Maquet, V., Lecomte, F., Hubert, P., & Evrard, B. (November 2008). Controlled release of drugs from multi-component biomaterials. Acta Biomaterialia, 4 (6), 1788-1796. doi:10.1016/j.actbio.2008.05.021

Mbinze Kindenge, J., Marini Djang'Eing'A, R., Lecomte, F., & Hubert, P. (2008). Qualification de l'appareillage. (ULiège - Université de Liège, PHAR0713-A-a).

Nizet, D., Jaspart, S., Brion, M., Lecomte, F., & Evrard, B. (2008). Use of supercritical fluids technology (PGSS) for the production of betametazone loaded solid lipid microparticles. Poster session presented at 6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Barcelona, Spain.

Rozet, E., Dewé, W., Morello, R., Chiap, P., Lecomte, F., Ziemons, E., Boos, K. S., Boulanger, B., Crommen, J., & Hubert, P. (2008). Risk-Based Approach for the Transfer of Quantitative Methods: Bioanalytical Applications. Journal of Chromatography. A, 1189, 32-41. doi:10.1016/j.chroma.2007.11.029

Lecomte, F., Aerts, J., Plenevaux, A., Lignon, S., Chapuis-Hugon, F., Chiap, P., Crommen, J., Luxen, A., Pichon, V., & Hubert, P. (September 2007). PPERFORMANCE EVALUATION OF TWO MIPS FOR THE SPE-LC-UV DETERMINATION OF p-[18F]MPPF IN PLASMA. Poster session presented at RDPA 2007, 12th Internatioinal Meeting on Recent Developments in Pharmaceutical Analysis, Island of Elba, Italy.

Lecomte, F., Aerts, J., Plenevaux, A., Lignon, S., Denjean, C., Chapuis-Hugon, F., Chiap, P., Crommen, J., Luxen, A., Pichon, V., & Hubert, P. (June 2007). DEVELOPMENT AND VALIDATION OF A METHOD FOR THE LC DETERMINATION p-[18F]MPPF IN PLASMA USING A MISPE. Poster session presented at HPLC 2007 - 31st International Symposium on High Performance Liquid Phase Separations and Related Techniques, Ghent, Belgium.

Lecomte, F., Aerts, J., Houbart, V., Plenevaux, A., Lignon, S., Chiap, P., Crommen, J., Luxen, A., Pichon, V., & Hubert, P. (2007). EVALUATION DE DEUX POLYMERES A EMPREINTES MOLECULAIRES POUR LE DOSAGE DU p-[18F]MPPF DANS LE PLASMA. Poster session presented at 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages - SEP07, Grenoble, France.

Rozet, E., Morello, R., Lecomte, F., Martin, G. B., Chiap, P., Crommen, J., Boos, K.-S., & Hubert, P. (05 December 2006). Performances of a multidimensional on-line SPE-LC-ECD method for the determination of three major catecholamines in native human urine: Validation, risk and uncertainty assessments. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 844 (2), 251-260. doi:10.1016/j.jchromb.2006.07.060

Lecomte, F., Aerts, J., Plenevaux, A., Lignon, S., Haber, G., Boulanger, B., Chiap, P., Luxen, A., & Hubert, P. (September 2006). EVALUATION OF MOLECULARLY IMPRINTED POLYMERS BY MEANS OF EXPERIMENTAL DESIGN PRIOR TO THE DETERMINATION OF p-[18F]MPPF IN PLASMA. Poster session presented at MIP2006 - Fourth International Workshop on Molecularly Imprinted Polymers, Cardiff, United Kingdom.

Lecomte, F., Boulanger, B., Hall, A. J., Sellergren, B., Crommen, J., Chiap, P., & Hubert, P. (March 2006). Développement d’une méthode de dosage automatisé du méthotrexate dans le plasma humain par couplage direct à la chromatographie liquide de l’extraction sur phase solide à empreintes moléculaires. Poster session presented at Forum LABO & Forum BIOTECH 2006, Paris, France.

Rozet, E., Dewé, W., Chiap, P., Lecomte, F., & Hubert, P. (2006). Le transfert d'une methode de dosage automatisee de la noradrenaline dans l'urine humaine: utilisation de l'erreur totale comme critere de decision. Acta Clinica Belgica. Supplementum, (1), 57-9.

Lecomte, F., Boulanger, B., Hall, A. J., Sellergren, B., Rozet, E., Crommen, J., Chiap, P., & Hubert, P. (September 2005). OPTIMIZATION OF MOLECULARLY IMPRINTED SOLID-PHASE EXTRACTION BY MEANS OF EXPERIMENTAL DESIGN PRIOR TO THE DETERMINATION OF METHOTREXATE IN HUMAN PLASMA. Poster session presented at RDPA 2005 - 11th International Meeting on Recent Developments in Pharmaceutical Analysis, Rimini, Italy.

Lecomte, F., Hall, A. J., Sellegren, B., Crommen, J., Hubert, P., & Chiap, P. (June 2005). Evaluation of molecularly imprinted polymers for selective extraction of methotrexate from human plasma prior to its LC determination. Poster session presented at   HPLC 2005 - 29th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Stockholm, Sweden.

Lecomte, F. (2005). Contribution à l’évaluation de deux polymères à empreintes moléculaires pour le dosage du méthotrexate dans le plasma. Unpublished DEA/DES thesis, ULiège - Université de Liège.
Jury: Hubert, P. (Promotor), Chiap, P. (Promotor), De Graeve, J., Charlier, C., & De Tullio, P.

Rozet, E., Dewe, W., Chiap, P., Lecomte, F., & Hubert, P. (2005). Le transfert d’une méthode de dosage de 3 catécholamines majeures dans l’urine humaine: utilisation de l’erreur totale comme critère de décision. Paper presented at 3èmes Journées Internationales de Toxicologie Hospitalière.

Rozet, E., Dewé, W., Chiap, P., Lecomte, F., & Hubert, P. (2005). Le transfert d’une méthode de dosage automatisée de 3 catécholamines majeures dans l’urine humaine: utilisation de l’erreur totale comme critère de décision. Paper presented at 3èmes Journées Internationales de Toxicologie Hospitalière, Liege, Belgium.