Publications and communications of Bakker, Julie

Bakker, J. (February 2022). The role of steroid hormones in the sexual differentiation of the human brain. Journal of Neuroendocrinology, 34 (2), 13050. doi:10.1111/jne.13050

Beking, T., Burke, S. M., Geuze, R. H., Staphorsius, A. S., Bakker, J., Groothuis, A. G. G., & Kreukels, B. P. C. (2020). Testosterone effects on functional amygdala lateralization: A study in adolescent transgender boys and cisgender boys and girls. Psychoneuroendocrinology, 111. doi:10.1016/j.psyneuen.2019.104461

Burke, S. M., van Heesewijk, J. O., Menks, W. M., Klink, D. T., Kreukels, B. P. C., Cohen-Kettenis, P. T., & Bakker, J. (2020). Postnatal Effects of Sex Hormones on Click-Evoked Otoacoustic Emissions: A Study of Adolescents with Gender Dysphoria. Archives of Sexual Behavior, 49 (2), 455-465. doi:10.1007/s10508-020-01652-8

Chen, D., Strang, J. F., Kolbuck, V. D., Rosenthal, S. M., Wallen, K., Waber, D. P., Steinberg, L., Sisk, C. L., Ross, J., Paus, T., Mueller, S. C., McCarthy, M. M., Micevych, P. E., Martin, C. L., Kreukels, B. P. C., Kenworthy, L., Herting, M. M., Herlitz, A., Haraldsen, I. R. J. H., & Garofalo, R. (2020). Consensus Parameter: Research Methodologies to Evaluate Neurodevelopmental Effects of Pubertal Suppression in Transgender Youth. Transgender Health, 5 (4), 246-257. doi:10.1089/trgh.2020.0006

Bakker, J. (2019). The Sexual Differentiation of the Human Brain: Role of Sex Hormones Versus Sex Chromosomes. Current Topics in Behavioral Neurosciences. doi:10.1007/7854_2018_70

Hellier, V., Brock, O., & Bakker, J. (2019). The Role of Kisspeptin in Sexual Behavior. Seminars in Reproductive Medicine, 37 (2), 84-92. doi:10.1055/s-0039-3400992

Muraille, E., de kerchove, A., Muylkens, B., Malgrange, B., Nicaise, C., Léna, C., Gueydan, C., Andris, F., Bureau, F., Tissir, F., Gofflot, F., Vassart, G., Balthazart, J., Vandeweerd, J.-M., Bakker, J., Duqué, J., Laurence, R., Nguyen, L., Schetgen, M., & De Tiège, X. (2018). Expérimentation animale: la recette d'une polémique scientifique. La Libre Belgique.

Bakker, J., Balthazart, J., Baron, F., Beguin, Y., Bettendorff, L., Blanpain, C., Bureau, F., Caers, J., Cani, P., Cataldo, D., Cornil, C., Clercx, C., Cloots, R., Colige, A., Daube, G., De Backer, O., de Kerchove d'Exaerde, A., Desmecht, D., Desmet, C., & Wittamer, V. (2018). La souris, le patient, et le faux expert. Décryptage d'une mystification. Le Vif. L'Express.

Drion, P., Corhay, A., Haubruge, E., Cloots, R., Rentier, B., Balthazart, J., RADERMECKER, R., Bureau, F., DEFRAIGNE, J., Malgrange, B., Nguyen, L., Desmecht, D., Bakker, J., Vanderplasschen, A., Seutin, V., Noël, A., & Foidart, J.-M. (2018). Analyse détaillée de la seconde version de l’avant-projet de Code du bien-être animal wallon. Lecture commentée au 21/03/2018 du Chapitre 8 (Expérimentation animale).

Hellier, V., Brock, O., Candlish, M., Desroziers, E., Aoki, M., Mayer, C., Piet, R., Herbison, A., Colledge, W. H., Prevot, V., Boehm, U., & Bakker, J. (2018). Female sexual behavior in mice is controlled by kisspeptin neurons. Nature Communications, 9 (1), 400. doi:10.1038/s41467-017-02797-2

Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., & Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique.

Baum, M. J., & Bakker, J. (2017). Reconsidering Prenatal Hormonal Influences on Human Sexual Orientation: Lessons from Animal Research. Archives of Sexual Behavior. doi:10.1007/s10508-017-0994-5

Desroziers, E., Brock, O., & Bakker, J. (2017). Potential contribution of progesterone receptors to the development of sexual behavior in male and female mice. Hormones and Behavior. doi:10.1016/j.yhbeh.2016.05.008

Koopman, A. C. M., Taziaux, M., & Bakker, J. (2017). Age-related changes in the morphology of tanycytes in the human female infundibular nucleus/median eminence. Journal of Neuroendocrinology, 29 (5). doi:10.1111/jne.12467

van Hemmen, J., Cohen-Kettenis, P. T., Steensma, T. D., Veltman, D. J., & Bakker, J. (2017). Do sex differences in CEOAEs and 2D:4D ratios reflect androgen exposure? A study in women with complete androgen insensitivity syndrome. Biology of Sex Differences, 8, 11. doi:10.1186/s13293-017-0132-z

van Hemmen, J., Saris, I. M. J., Cohen-Kettenis, P. T., Veltman, D. J., Pouwels, P. J. W., & Bakker, J. (2017). Sex Differences in White Matter Microstructure in the Human Brain Predominantly Reflect Differences in Sex Hormone Exposure. Cerebral Cortex. doi:10.1093/cercor/bhw156

Brus, M., Trouillet, A.-C., Hellier, V., & Bakker, J. (2016). Estradiol-induced neurogenesis in the female accessory olfactory bulb is required for the learning of the male odor. Journal of Neurochemistry. doi:10.1111/jnc.13677

Burke, S. M., Kreukels, B. P. C., Cohen-Kettenis, P. T., Veltman, D. J., Klink, D. T., & Bakker, J. (2016). Male-typical visuospatial functioning in gynephilic girls with gender dysphoria - organizational and activational effects of testosterone. Journal of Psychiatry and Neuroscience, 41 (4), 150147. doi:10.1503/jpn.150147

Taziaux, M., Staphorsius, A. S., Ghatei, M. A., Bloom, S. R., Swaab, D. F., & Bakker, J. (2016). Kisspeptin Expression in the Human Infundibular Nucleus in Relation to Sex, Gender Identity, and Sexual Orientation. Journal of Clinical Endocrinology and Metabolism, 101 (6), 2380-9. doi:10.1210/jc.2015-4175

Hoekzema, E., Schagen, S. E. E., Kreukels, B. P. C., Veltman, D. J., Cohen-Kettenis, P. T., Delemarre-van de Waal, H., & Bakker, J. (2015). Regional volumes and spatial volumetric distribution of gray matter in the gender dysphoric brain. Psychoneuroendocrinology, 55C, 59-71. doi:10.1016/j.psyneuen.2015.01.016

Hellier, V., & Bakker, J. (27 January 2014). Kisspeptin and neuronal nitric oxide signaling are important in female sexual behavior. Poster session presented at GIGA Day.

Burke, S. M., Cohen-Kettenis, P. T., Veltman, D. J., Klink, D. T., & Bakker, J. (2014). Hypothalamic response to the chemo-signal androstadienone in gender dysphoric children and adolescents. Frontiers in Endocrinology, 5, 60. doi:10.3389/fendo.2014.00060

Burke, S. M., Menks, W. M., Cohen-Kettenis, P. T., Klink, D. T., & Bakker, J. (2014). Click-Evoked Otoacoustic Emissions in Children and Adolescents with Gender Identity Disorder. Archives of Sexual Behavior. doi:10.1007/s10508-014-0278-2

Baum, M. J., & Bakker, J. (2013). Roles of sex and gonadal steroids in mammalian pheromonal communication. Frontiers in Neuroendocrinology, 34 (4), 268-84. doi:10.1016/j.yfrne.2013.07.004

Brock, O., & Bakker, J. (2013). The two kisspeptin neuronal populations are differentially organized and activated by estradiol in mice. Endocrinology. doi:10.1210/en.2013-1120

Brock, O., Bakker, J., & Baum, M. J. (2013). Assessment of urinary pheromone discrimination, partner preference, and mating behaviors in female mice. Methods in Molecular Biology, 1068, 319-29. doi:10.1007/978-1-62703-619-1_24

Geenen, V., Bakker, J., Hoekzema, E., & Scantamburlo, G. (2012). Deregulation of Oxytocin and Vasopressin in Williams Syndrome: A New Model For Exploring Neurogenetics and Neurobiology of Human Social Behavior. Eprint/Working paper retrieved from https://orbi.uliege.be/2268/133427.

Brock, O., Keller, M., Douhard, Q., & Bakker, J. (2012). Female mice deficient in alpha-fetoprotein show female-typical neural responses to conspecific-derived pheromones. PLoS ONE, 7 (6), 39204. doi:10.1371/journal.pone.0039204

Burke, S. M., Veltman, D. J., Gerber, J., Hummel, T., & Bakker, J. (2012). Heterosexual men and women both show a hypothalamic response to the chemo-signal androstadienone. PLoS ONE, 7 (7), 40993. doi:10.1371/journal.pone.0040993

Szymanski, L., & Bakker, J. (2012). Aromatase knockout mice show normal steroid-induced activation of gonadotrophin-releasing hormone neurones and luteinising hormone surges with a reduced population of kisspeptin neurones in the rostral hypothalamus. Journal of Neuroendocrinology, 24 (9), 1222-33. doi:10.1111/j.1365-2826.2012.02334.x

Taziaux, M., Swaab, D. F., & Bakker, J. (2012). Sex differences in the neurokinin B system in the human infundibular nucleus. Journal of Clinical Endocrinology and Metabolism, 97 (12), 2210-20. doi:10.1210/jc.2012-1554

Brock, O., & Bakker, J. (2011). Potential contribution of prenatal estrogens to the sexual differentiation of mate preferences in mice. Hormones and Behavior, 59 (1), 83-9. doi:10.1016/j.yhbeh.2010.10.012

Brock, O., Baum, M. J., & Bakker, J. (2011). The development of female sexual behavior requires prepubertal estradiol. Journal of Neuroscience, 31 (15), 5574-8. doi:10.1523/JNEUROSCI.0209-11.2011

Naninck, E. F. G., Lucassen, P. J., & Bakker, J. (2011). Sex differences in adolescent depression: do sex hormones determine vulnerability? Journal of Neuroendocrinology, 23 (5), 383-92. doi:10.1111/j.1365-2826.2011.02125.x

Taziaux, M., Keller, M., Balthazart, J., & Bakker, J. (2011). Rapid activation of phosphorylated mitogen-activated protein kinase after sexual stimulation in male mice. Neuroreport, 22 (6), 294-8. doi:10.1097/WNR.0b013e3283460f35

Veyrac, A., & Bakker, J. (2011). Postnatal and adult exposure to estradiol differentially influences adult neurogenesis in the main and accessory olfactory bulb of female mice. FASEB Journal, 25 (3), 1048-57. doi:10.1096/fj.10-172635

Veyrac, A., Wang, G., Baum, M. J., & Bakker, J. (2011). The main and accessory olfactory systems of female mice are activated differentially by dominant versus subordinate male urinary odors. Brain Research, 1402, 20-9. doi:10.1016/j.brainres.2011.05.035

Bakker, J., & Brock, O. (2010). Early oestrogens in shaping reproductive networks: Evidence for a potential organizational role of oestradiol in female brain development. Journal of Neuroendocrinology, 22, 728-735. doi:10.1111/j.1365-2826.2010.02016.x

Bakker, J., Pierman, S., & Gonzalez-Martinez, D. (2010). Effects of aromatase mutation (ArKO) on the sexual differentiation of kisspeptin neuronal numbers and their activation by same versus opposite sex urinary pheromones. Hormones and Behavior, 57 (4-5), 390-5. doi:10.1016/j.yhbeh.2009.11.005

Brock, O., Douhard, Q., Baum, M. J., & Bakker, J. (2010). Reduced prepubertal expression of progesterone receptor in the hypothalamus of female aromatase knock-out mouse. Endocrinology. doi:10.1210/en.2009-1379

Brock, O., Keller, M., Veyrac, A., Douhard, Q., & Bakker, J. (2010). Short term treatment with estradiol decreases the rate of newly generated cells in the subventricular zone and main olfactory bulb in adult female mice. Neuroscience. doi:10.1016/j.neuroscience.2009.12.050

Keller, M., Pawluski, J., Brock, O., Douhard, Q., & Bakker, J. (2010). The alpha-fetoprotein knock-out mouse model suggests that parental behavior is sexually differentiated under the influence of prenatal estradiol. Hormones and Behavior. doi:10.1016/j.yhbeh.2010.01.013

Keller, M., Pillon, D., & Bakker, J. (2010). Olfactory systems in mate recognition and sexual behavior. Vitamins and Hormones, 83, 331-50. doi:10.1016/S0083-6729(10)83014-6

Keller, M., Baum, M. J., Brock, O., & Bakker, J. (2009). The main and accessory olfactory systems interact in the control of mate recognition and sexual behavior. Behavioural Brain Research. doi:10.1016/j.bbr.2009.01.020

Gonzalez-Martinez, D., De Mees, C., Douhard, Q., Szpirer, C., & Bakker, J. (17 January 2008). Absence of Gnrh1 and Kiss1 Activation in Alpha-Fetoprotein Knockout Mice: Prenatal Estrogens Defeminize the Potential to Show Preovulatory Lh Surges. Endocrinology, 149 (5), 2333-2340. doi:10.1210/en.2007-1422

Bakker, J., & Baum, M. J. (January 2008). Role for Estradiol in Female-Typical Brain and Behavioral Sexual Differentiation. Frontiers in Neuroendocrinology, 29 (1), 1-16. doi:10.1016/j.yfrne.2007.06.001

Pierman, S., Douhard, Q., & Bakker, J. (January 2008). Evidence for a Role of Early Oestrogens in the Central Processing of Sexually Relevant Olfactory Cues in Female Mice. European Journal of Neuroscience, 27 (2), 423-31. doi:10.1111/j.1460-9568.2007.06016.x

Pierman, S., Sica, M., Allieri, F., Viglietti-Panzica, C., Panzica, G. C., & Bakker, J. (2008). Activational effects of estradiol and dihydrotestosterone on social recognition and the arginine-vasopressin immunoreactive system in male mice lacking a functional aromatase gene. Hormones and Behavior, 54 (1), 98-106. doi:10.1016/j.yhbeh.2008.02.001

Martel, K. L., Keller, M., Douhard, Q., Bakker, J., & Baum, M. J. (27 June 2007). Comparison of urinary odor-induced glomerular activation in the main olfactory bulb of aromatase knock-out and wild type female mice. Neuroscience Letters, 421 (2), 101-105. doi:10.1016/j.neulet.2007.05.044

Keller, M., Douhard, Q., Baum, M. J., & Bakker, J. (October 2006). Sexual experience does not compensate for the disruptive effects of zinc sulfate-lesioning of the main olfactory epithelium on sexual behavior in male mice. Chemical Senses, 31 (8), 753-762. doi:10.1093/chemse/bjl018

Bakker, J. (May 2006). L’α-foetoprotéine protège le cerveau femelle en développement des effets masculinisants et déféminisants des oestrogènes. MS. Medecine Sciences, 22 (5), 459-461. doi:10.1051/medsci/2006225459

Keller, M., Douhard, Q., Baum, M. J., & Bakker, J. (May 2006). Destruction of the main olfactory epithelium reduces female sexual behavior and olfactory investigation in female mice. Chemical Senses, 31 (4), 315-323. doi:10.1093/chemse/bjj035

Wesson, D. W., Keller, M., Douhard, Q., Baum, M. J., & Bakker, J. (May 2006). Enhanced urinary odor discrimination in female aromatase knockout (ArKO) mice. Hormones and Behavior, 49 (5), 580-586. doi:10.1016/j.yhbeh.2005.12.013

De Mees, C., Laes, J.-F., Bakker, J., Smitz, J., Hennuy, B., Van Vooren, P., Gabant, P., Szpirer, J., & Szpirer, C. (March 2006). Alpha-fetoprotein controls female fertility and prenatal development of the gonadotropin-releasing hormone pathway through an antiestrogenic action. Molecular and Cellular Biology, 26 (5), 2012-2018. doi:10.1128/MCB.26.5.2012-2018.2006

Keller, M., Pierman, S., Douhard, Q., Baum, M. J., & Bakker, J. (January 2006). The vomeronasal organ is required for the expression of lordosis behaviour, but not sex discrimination in female mice. European Journal of Neuroscience, 23 (2), 521-530. doi:10.1111/j.1460-9568.2005.04589.x

Bakker, J. (June 2003). Sexual differentiation of the neuroendocrine mechanisms regulating mate recognition in mammals. Journal of Neuroendocrinology, 15 (6), 615-621. doi:10.1046/j.1365-2826.2003.01036.x

Bakker, J., Woodley, S. K., Kelliher, K. R., & Baum, M. J. (February 2002). Sexually dimorphic activation of galanin neurones in the ferret's dorsomedial preoptic area/anterior hypothalamus after mating. Journal of Neuroendocrinology, 14 (2), 116-125. doi:10.1046/j.0007-1331.2001.00751.x

Dominguez, E., Portillo, W., Baum, M. J., Bakker, J., & Paredes, R. (2002). Effect of prenatal androgen receptor antagonist or aromatase inhibitor on the differentiation of neuronal Fos responses to estrous female pheromones in the rat accessory olfactory system. Physiology and Behavior, 75, 337-346.

Bakker, J., & Baum, M. J. (2000). Neuroendocrine regulation of GnRH release in induced ovulators. Frontiers in Neuroendocrinology, 21 (3), 220-62. doi:10.1006/frne.2000.0198

Bakker, J., & Baum, M. J. (2000). Effect of gonadal steroids on pituitary LH secretion and mediobasal hypothalamic GnRH mRNA in ferrets. Journal of Reproduction and Fertility, 119 (2), 315-21. doi:10.1530/jrf.0.1190315

Bakker, J., Rubin, B. S., & Baum, M. J. (1999). Changes in mediobasal hypothalamic gonadotropin-releasing hormone messenger ribonucleic acid levels induced by mating or ovariectomy in a reflex ovulator, the ferret. Endocrinology, 140 (2), 595-602. doi:10.1210/endo.140.2.6519

Bakker, J., Pool, C. W., Sonnemans, M., van Leeuwen, F. W., & Slob, A. K. (1997). Quantitative estimation of estrogen and androgen receptor-immunoreactive cells in the forebrain of neonatally estrogen-deprived male rats. Neuroscience, 77 (3), 911-9. doi:10.1016/S0306-4522(96)00423-X

Bakker, J., Baum, M. J., & Slob, A. K. (1996). Neonatal inhibition of brain estrogen synthesis alters adult neural Fos responses to mating and pheromonal stimulation in the male rat. Neuroscience, 74 (1), 251-60. doi:10.1016/0306-4522(96)00096-6