Publications and communications of Jacobs, Nathalie

Articles in scientific journals with peer reviewing

NOEL, L., Fransolet, M., Jacobs, N., Foidart, J.-M., Nisolle, M., & Munaut, C. (2020). A paracrine interaction between granulosa cells and leukocytes in the preovulatory follicle causes the increase in follicular G-CSF levels. J Assist Reprod Genet, 37, 405-416. doi:10.1007/s10815-020-01692-y

Murall, C. L., Rahmoun, M., Selinger, C., Baldellou, M., Bernat, C., Bonneau, M., Boue, V., Buisson, M., Christophe, G., D'Auria, G., Taroni, F. D., Foulongne, V., Froissart, R., Graf, C., Grasset, S., Groc, S., Hirtz, C., Jaussent, A., Lajoie, J., & Alizon, S. (2019). Natural history, dynamics, and ecology of human papillomaviruses in genital infections of young women: protocol of the PAPCLEAR cohort study. BMJ Open, 9 (6), 025129. doi:10.1136/bmjopen-2018-025129

Yazdani, R., Shams-Bakhsh, M., Hassani-Mehraban, A., Arab, S. S., Thelen, N., Thiry, M., Crommen, J., Fillet, M., Jacobs, N., Brans, A., & Servais, A.-C. (2019). Production and characterization of virus-like particles of grapevine fanleaf virus presenting L2 epitope of human papillomavirus minor capsid protein. BMC Biotechnology, 19 (1), 81. doi:10.1186/s12896-019-0566-y

Polese, B., Gridelet, V., Perrier d'Hauterive, S., Charlet-Renard, J. D. C., Munaut, C., Martens, H., Vermijlen, D., King, I. L., Jacobs, N., & Geenen, V. (29 January 2018). Accumulation of IL-17+ Vgamma6+ gamma-delta T cells in pregnant mice is not associated with spontaneous abortion. Clinical and Translational Immunology, 7, 1008. doi:10.1002/cti2.1008

Van hede, D., Polese, B., Humblet, C., Wilharm, A., Renoux, V., Dortu, E., de Leval, L., Delvenne, P., Desmet, C., Bureau, F., Vermijlen, D., & Jacobs, N. (2017). Human papillomavirus oncoproteins induce a reorganization of epithelial-associated gammadelta T cells promoting tumor formation. Proceedings of the National Academy of Sciences of the United States of America, 114 (43), 9056-E9065. doi:10.1073/pnas.1712883114

EL SHAZLY, A., Castillo- Doloriert, H., Bisig, B., Lefèbvre, P., Delvenne, P., & Jacobs, N. (2013). Novel cooperation between CX3CL1 and CCL26 inducing NK cell chemotaxis via CX3CR1: a possible mechanism for NK cell infiltration of the allergic nasal tissue. Clinical and Experimental Allergy, 43 (3), 322-31. doi:10.1111/cea.12022

Langers, I., Renoux, V., Thiry, M., Delvenne, P., & Jacobs, N. (2012). Natural Killer cells - role in local tumor growth and metastasis. Biologics: Targets and Therapy.

Renoux, V., Bisig, B., Langers, I., Dortu, E., Clemenceau, B., Thiry, M., Deroanne, C., Colige, A., Boniver, J., Delvenne, P., & Jacobs, N. (November 2011). Human papillomavirus entry into NK cells requires CD16 expression and triggers cytotoxic activity and cytokine secretion. European Journal of Immunology, 41 (11), 3240-3252. doi:10.1002/eji.201141693

Masset, A., Maillard, C., Sounni, N. E., Jacobs, N., Bruyère, F., Delvenne, P., Tacke, M., Reinheckel, T., Foidart, J.-M., Coussens, L., & Noël, A. (2011). Unimpeded skin carcinogenesis in K14-HPV16 transgenic mice deficient for plasminogen activator inhibitor. International Journal of Cancer, 128 (2), 283-93. doi:10.1002/ijc.25326

Jacobs, N., Bartlett, N. W., Clark, R. H., & Smith, G. L. (2008). Vaccinia virus lacking the Bcl-2-like protein N1 induces a stronger natural killer cell response to infection. Journal of General Virology, 89 (Pt 11), 2877-81. doi:10.1099/vir.0.2008/004119-0

Hubert, P., Jacobs, N., Caberg, J.-H., Boniver, J., & Delvenne, P. (October 2007). The cross-talk between dendritic and regulatory T cells: good or evil? Journal of Leukocyte Biology, 82 (4), 781-94. doi:10.1189/jlb.1106694

Delvenne, P., Herman, L., Kholod, N., Caberg, J.-H., Herfs, M., Boniver, J., Jacobs, N., & Hubert, P. (2007). Role of hormone cofactors in the human papillomavirus-induced carcinogenesis of the uterine cervix. Molecular and Cellular Endocrinology, 264 (1-2), 1-5. doi:10.1016/j.mce.2006.10.014

Gubser, C., Goodbody, R., Ecker, A., Brady, G., O'Neill, L. A. J., Jacobs, N., & Smith, G. L. (2007). Camelpox virus encodes a schlafen-like protein that affects orthopoxvirus virulence. Journal of General Virology, 88 (Pt 6), 1667-76. doi:10.1099/vir.0.82748-0

Jacobs, N., Boniver, J., Hubert, P., & Delvenne, P. (2007). Dendritic Cells: More Than Just Adaptive Immunity Inducers? Current Immunology Reviews, 2, 17-22. doi:10.2174/157339507779802214

Zeddou, M., Rahmouni, S., Vandamme, A., Jacobs, N., Frippiat, F., Leonard, P., SCHAAF-LAFONTAINE, N., Vaira, D., Boniver, J., & Moutschen, M. (2007). Downregulation of CD94/NKG2A inhibitory receptors on CD8+ T cells in HIV infection is more pronounced in subjects with detected viral load than in their aviraemic counterparts. Retrovirology, 4, 72. doi:10.1186/1742-4690-4-72

Bindels, S., Mestdagt, M., Van de Walle, C., Jacobs, N., Volders, L., Noël, A., van Roy, F., Berx, G., Foidart, J.-M., & Gilles, C. (17 August 2006). Regulation of vimentin by SIP1 in human epithelial breast tumor cells. Oncogene, 25 (36), 4975-4985. doi:10.1038/sj.onc.1209511

Chen, R. A.-J., Jacobs, N., & Smith, G. L. (2006). Vaccinia virus strain Western Reserve protein B14 is an intracellular virulence factor. Journal of General Virology, 87 (Pt 6), 1451-8. doi:10.1099/vir.0.81736-0

Jacobs, N., Chen, R. A.-J., Gubser, C., Najarro, P., & Smith, G. L. (2006). Intradermal immune response after infection with Vaccinia virus. Journal of General Virology, 87 (Pt 5), 1157-61. doi:10.1099/vir.0.81556-0

Lechanteur, C., Jacobs, N., Greimers, R., Benoit, V., Deregowski, V., Chariot, A., Merville, M.-P., & Bours, V. (03 March 2005). Low daunomycin concentrations protect colorectal cancer cells from hypoxia-induced apoptosis. Oncogene, 24 (10), 1788-1793. doi:10.1038/sj.onc.1208436

Hallez, S., Simon, P., Maudoux, F., Doyen, J., Noël, J.-C., Beliard, A., Capelle, X., Buxant, F., Fayt, I., Lagrost, A.-C., Hubert, P., Gerday, C., Burny, A., Boniver, J., Foidart, J.-M., Delvenne, P., & Jacobs, N. (July 2004). Phase I/II trial of immunogenicity of a human papillomavirus (HPV) type 16 E7 protein-based vaccine in women with oncogenic HPV-positive cervical intraepithelial neoplasia. Cancer Immunology, Immunotherapy, 53 (7), 642-650. doi:10.1007/s00262-004-0501-4

Benoit, V., Chariot, A., Delacroix, L., Deregowski, V., Jacobs, N., Merville, M.-P., & Bours, V. (2004). Caspase-8-dependent HER-2 cleavage in response to tumor necrosis factor alpha stimulation is counteracted by nuclear factor kappa B through c-FLIP-L expression. Cancer Research, 64 (8), 2684-2691. doi:10.1158/0008-5472.CAN-03-2914

Remoue, F.* , Jacobs, N.* , Miot, V., Boniver, J., & Delvenne, P. (December 2003). High intraepithelial expression of estrogen and progesterone receptors in the transformation zone of the uterine cervix. American Journal of Obstetrics and Gynecology, 189 (6), 1660-1665. doi:10.1016/S0002-9378(03)00852-4

Bentires-Alj, M., Barbu, V., Fillet, M., Chariot, A., Relic, B., Jacobs, N., Gielen, J., Merville, M.-P., & Bours, V. (2003). NF-κB transcription factor induces drug resistance through MDR1 expression in cancer cells. Oncogene, 22, 90-97. doi:10.1038/sj.onc.1206056

Jacobs, N., Renard, I., Al-Saleh, W., Hubert, P., Doyen, J., Kedzia, W., Boniver, J., & Delvenne, P. (2003). Distinct T cell subsets and cytokine production in cultures derived from transformation zone and squamous intraepithelial lesion biopsies of the uterine cervix. American Journal of Reproductive Immunology, 49 (1), 6-13. doi:10.1034/j.1600-0897.2003.01109.x

Renard, I., Mezzanzanica, D., Canevari, S., Ferrini, S., Boniver, J., Delvenne, P., & Jacobs, N. (January 2002). Anti-CD3/anti-epidermal growth factor receptor-bispecific antibody retargeting of lymphocytes against human neoplastic keratinocytes in an autologous organotypic culture model. American Journal of Pathology, 160 (1), 113-122. doi:10.1016/S0002-9440(10)64355-6

Delvenne, P., Hubert, P., Jacobs, N., Giannini, S., Havard, L., Renard, I., Saboulard, D., & Boniver, J. (2001). The organotypic culture of HPV-transformed keratinocytes: an effective in vitro model for the development of new immunotherapeutic approaches for mucosal (pre)neoplastic lesions. Vaccine, 19 (17-19), 2557-64. doi:10.1016/S0264-410X(00)00489-8

Giannini, S., Al-Saleh, W., Piron, H., Jacobs, N., Doyen, J., Boniver, J., & Delvenne, P. (August 1998). Cytokine Expression in Squamous Intraepithelial Lesions of the Uterine Cervix: Implications for the Generation of Local Immunosuppression. Clinical and Experimental Immunology, 113 (2), 183-9. doi:10.1046/j.1365-2249.1998.00639.x

Jacobs, N., Mazzoni, A., Mezzanzanica, D., Negri, D. R., Valota, O., Colnaghi, M. I., MOUTSCHEN, M., Boniver, J., & Canevari, S. (July 1997). Efficiency of T Cell Triggering by Anti-Cd3 Monoclonal Antibodies (Mab) with Potential Usefulness in Bispecific Mab Generation. Cancer Immunology, Immunotherapy, 44 (5), 257-64. doi:10.1007/s002620050381

Jacobs, N., Greimers, R., Mazzoni, A., Trebak, M., Schaaf-Lafontaine, N., Boniver, J., & Moutschen, M. (July 1996). Further Characterization of Cytotoxic T Cells Generated by Short-Term Culture of Human Peripheral Blood Lymphocytes with Interleukin-2 and Anti-Cd3 Mab. Cancer Immunology, Immunotherapy, 42 (6), 369-75. doi:10.1007/s002620050296

Greimers, R., Trebak, M., Moutschen, M., Jacobs, N., & Boniver, J. (01 March 1996). Improved Four-Color Flow Cytometry Method Using Fluo-3 and Triple Immunofluorescence for Analysis of Intracellular Calcium Ion ([Ca2+]I) Fluxes among Mouse Lymph Node B- and T-Lymphocyte Subsets. Cytometry, 23 (3), 205-17. doi:10.1002/(SICI)1097-0320(19960301)23:3<205::AID-CYTO4>3.0.CO;2-H

Moutschen, M., Jacobs, N., Hoyoux, C., Martin-Simonet, M.-T., Schaaf-Lafontaine, N., & Boniver, J. (1994). Presence of gd TcR+ Tumor Infiltrating Lymphocytes (TILs) in One Case of Pediatric Osteogenic Sarcoma. International Journal of Pediatric Hematology/Oncology.

Jacobs, N., MOUTSCHEN, M., Boniver, J., Greimers, R., & Schaaf-Lafontaine, N. (February 1993). Efficient Immunoselection of Cytolytic Effectors with a Magnetic Cell Sorter. Research in Immunology, 144 (2), 141-50. doi:10.1016/0923-2494(93)80069-B

Scientific conferences in universities or research centers

Jacobs, N. (04 July 2019). Le Yin et le Yang de la réponse immunitaire dans les lésions induites par les papillomavirus humains. . Paper presented at 2ème journée Virus & Cancer.

Scientific congresses and symposiums

Published communications

Humblet-Baron, S., CASTERMANS, E., Vanbellinghen, J.-F., Hannon, M., Jacobs, N., WILLEMS, E., Ormenese, S., Beguin, Y., & Baron, F. (February 2009). What Is The Role For Regulatory T-Cells After Nonmyeloablative Conditioning? Biology of Blood and Marrow Transplantation, 15 (2), 122-123. doi:10.1016/j.bbmt.2008.12.377

Humblet-Baron, S., CASTERMANS, E., Vanbellighen, J.-F., Hannon, M., Jacobs, N., Beguin, Y., & Baron, F. (February 2008). What is the Role for Regulatory T-Cells after Nonmyeloablative conditioning. Biology of Blood and Marrow Transplantation, 14 (2), 136-137. doi:10.1016/j.bbmt.2007.12.383

Faccinetto, C., Lecut, C., Jacobs, N., Bours, V., & Oury, C. (2007). P2X1 receptors as new regulators of neutrophil life span. Journal of Thrombosis and Haemostasis.

Oral communications or posters

Van hede, D., Polese, B., Humblet, C., Wilharm, A., Renoux, V., DORTU, E., de Leval, L., Delvenne, P., Desmet, C., Bureau, F., Vermijlen, D., & Jacobs, N. (June 2018). Human papillomavirus oncoproteins induce a reorganization of epithelial-associated γδ T cells promoting tumor formation. Poster session presented at Gamma delta conferance, Bordeaux, France.

Renoux, V., Bisig, B., Langers, I., Bastin, R., Thiry, M., Deroanne, C., Delvenne, P., & Jacobs, N. (May 2013). Human papillomavirus entry into NK cells requires CD16 expression and triggers cytotoxic activity and cytokine secretion. Poster session presented at Gordon Conference Virus & Cell, Lucca, Italy.

Renoux, V., Langers, I., Dortu, E., Bisig, B., Thiry, M., Deroanne, C., Boniver, J., Delvenne, P., & Jacobs, N. (28 January 2013). Human papillomavirus entry into NK cells requires CD16 expression and triggers cytotoxic activity and cytokine secretion. Paper presented at GIGA-Day, Liège, Belgium.

Brohée, L., Bastin, R., Wingert, S., Netter, P., Waltz, C., Delvenne, P., & Jacobs, N. (2013). Expansion of CD16+ CD56+ NK cells in vericyte® NK cell growth medium. Poster session presented at 14th Meeting of the Society for Natural Immunity, Heidelberg, Germany.

EL SHAZLY, A., Castillo-Doloriert, H., Bisig, B., LEFEBVRE, P., Delvenne, P., & Jacobs, N. (2013). Novel cooperation between CX3CL1 and CCL26 inducing NK cell chemotaxis via CX3CR1: a possible mechanism for NK cell infiltration of the allergic nasal tissue. Poster session presented at 14th Meeting of the Society for Natural Immunity, Heidelberg, Germany.

Renoux, V., Langers, I., Clémenceau, B., Thiry, M., Bisig, B., Deroanne, C., Dortu, E., Boniver, J., Delvenne, P., & Jacobs, N. (13 September 2011). Macropinocytosis of human papillomaviruses in natural killer cells via CD16 induces cytotoxic granule exocytosis and cytokine secretion. Poster session presented at IUMS International Congress of Virology, Sapporo, Japan.

Jacobs, N., Renoux, V., Bisig, B., Langers, I., Dortu, E., Clémenceau, B., Thiry, M., Deroanne, C., Boniver, J., & Delvenne, P. (2011). HPV triggers NK cell cytotoxic activity and cytokine secretion. Paper presented at 27th International Papillomavirus Conference, Berlin, Germany.

Hubert, P., Doyen, J., Chapelle, X., Evrard, B., Gerday, C., Boniver, J., Foidart, J.-M., & Jacobs, N. (2007). Phase I/IIclinical trial of local GM-CSF application in patients with cervical HPV-associated low grade squamous intraepithelial lesions. Paper presented at 24th International Papillomavirus Conference and Clinical Workshops, Bejing, China.

Jacobs, N., & Delvenne, P. (2007). Experimental models/cell model: organotypic cultures. Paper presented at HPV and Skin Cancer 4th International Meeting, Besançon, France.

Book chapters and contributions to collective works

Jacobs, N., Renard, I., Pisvin, S., Hubert, P., Boniver, J., & Delvenne, P. (2000). IL10 production in cultures of lymphocytes derived from biopsies of normal exocervix, transformation zone and squamous intraepithelial lesion. In J. Monsonego (Ed.), 4th International Multidisciplinary Congress - Eurogin 2000 (pp. 355-362). Pianoro, Italy: International Proceedings Division, Monduzzi Editore.

Other publications and communications

Speeches and writings for a general audience

General audience and popularisation articles

Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., & Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique.