Publications and communications of Jacobs, Nathalie

Articles in scientific journals with peer reviewing

Van Hulst, G., Jorssen, J., Jacobs, N., Henket, M., Louis, R., Schleich, F., Bureau, F., & Desmet, C. (2021). Anti-IL-5 mepolizumab minimally influences residual blood eosinophils in severe asthma. European Respiratory Journal. doi:10.1183/13993003.00935-2021

NOEL, L., Fransolet, M., Jacobs, N., Foidart, J.-M., Nisolle, M., & Munaut, C. (2020). A paracrine interaction between granulosa cells and leukocytes in the preovulatory follicle causes the increase in follicular G-CSF levels. J Assist Reprod Genet, 37, 405-416. doi:10.1007/s10815-020-01692-y

Murall, C. L., Rahmoun, M., Selinger, C., Baldellou, M., Bernat, C., Bonneau, M., Boue, V., Buisson, M., Christophe, G., D'Auria, G., Taroni, F. D., Foulongne, V., Froissart, R., Graf, C., Grasset, S., Groc, S., Hirtz, C., Jaussent, A., Lajoie, J., & Alizon, S. (2019). Natural history, dynamics, and ecology of human papillomaviruses in genital infections of young women: protocol of the PAPCLEAR cohort study. BMJ Open, 9 (6), 025129. doi:10.1136/bmjopen-2018-025129

Yazdani, R., Shams-Bakhsh, M., Hassani-Mehraban, A., Arab, S. S., Thelen, N., Thiry, M., Crommen, J., Fillet, M., Jacobs, N., Brans, A., & Servais, A.-C. (2019). Production and characterization of virus-like particles of grapevine fanleaf virus presenting L2 epitope of human papillomavirus minor capsid protein. BMC Biotechnology, 19 (1), 81. doi:10.1186/s12896-019-0566-y

Polese, B., Gridelet, V., Perrier d'Hauterive, S., Charlet-Renard, J. D. C., Munaut, C., Martens, H., Vermijlen, D., King, I. L., Jacobs, N., & Geenen, V. (29 January 2018). Accumulation of IL-17+ Vgamma6+ gamma-delta T cells in pregnant mice is not associated with spontaneous abortion. Clinical and Translational Immunology, 7, 1008. doi:10.1002/cti2.1008

Bettonville, V., Nicol, J. T. J., Furst, T., Thelen, N., Piel, G., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (2017). Quantitation and biospecific identification of virus-like particles of human papillomavirus by capillary electrophoresis. Talanta, 175, 325-330. doi:10.1016/j.talanta.2017.07.046

Van hede, D., Polese, B., Humblet, C., Wilharm, A., Renoux, V., Dortu, E., de Leval, L., Delvenne, P., Desmet, C., Bureau, F., Vermijlen, D., & Jacobs, N. (2017). Human papillomavirus oncoproteins induce a reorganization of epithelial-associated gammadelta T cells promoting tumor formation. Proceedings of the National Academy of Sciences of the United States of America, 114 (43), 9056-E9065. doi:10.1073/pnas.1712883114

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (2016). Study of intact virus-like particles of human papillomavirus by capillary electrophoresis. Electrophoresis, 37, 579-586. doi:10.1002/elps.201500431

Langers, I., Renoux, V., Reschner, A., Touze, A., Coursaget, P., Boniver, J., Koch, J., Delvenne, P., & Jacobs, N. (December 2014). Natural killer and dendritic cells collaborate in the immune response induced by the vaccine against uterine cervical cancer. European Journal of Immunology, 44, 3585-3595. doi:10.1002/eji.201444594

Van hede, D., Langers, I., DELVENNE, P., & Jacobs, N. (2014). Origin and immunoescape of uterine cervical cancer. Presse Médicale. doi:10.1016/j.lpm.2014.09.005

EL SHAZLY, A., Castillo- Doloriert, H., Bisig, B., Lefèbvre, P., Delvenne, P., & Jacobs, N. (2013). Novel cooperation between CX3CL1 and CCL26 inducing NK cell chemotaxis via CX3CR1: a possible mechanism for NK cell infiltration of the allergic nasal tissue. Clinical and Experimental Allergy, 43 (3), 322-31. doi:10.1111/cea.12022

Guenin, S., Mouallif, M., Hubert, P., Jacobs, N., Krusy, N., Duray, A., Ennaji, M. M., Saussez, S., & Delvenne, P. (2013). Interleukin-32 expression is associated with a poorer prognosis in head and neck squamous cell carcinoma. Molecular Carcinogenesis, 53 (8), 667-673. doi:10.1002/mc.21996

Langers, I., Renoux, V., Thiry, M., Delvenne, P., & Jacobs, N. (2012). Natural Killer cells - role in local tumor growth and metastasis. Biologics: Targets and Therapy.

Renoux, V., Bisig, B., Langers, I., Dortu, E., Clemenceau, B., Thiry, M., Deroanne, C., Colige, A., Boniver, J., Delvenne, P., & Jacobs, N. (November 2011). Human papillomavirus entry into NK cells requires CD16 expression and triggers cytotoxic activity and cytokine secretion. European Journal of Immunology, 41 (11), 3240-3252. doi:10.1002/eji.201141693

Masset, A., Maillard, C., Sounni, N. E., Jacobs, N., Bruyère, F., Delvenne, P., Tacke, M., Reinheckel, T., Foidart, J.-M., Coussens, L., & Noël, A. (2011). Unimpeded skin carcinogenesis in K14-HPV16 transgenic mice deficient for plasminogen activator inhibitor. International Journal of Cancer, 128 (2), 283-93. doi:10.1002/ijc.25326

Hubert, P., Doyen, J., Capelle, X., Arafa, M., Renoux, V., Bisig, B., Seidel, L., Evrard, B., Bousarghin, L., Gerday, C., Boniver, J., Foidart, J.-M., Delvenne, P., & Jacobs, N. (2010). Local applications of GM-CSF induce the recruitment of immune cells in cervical low-grade squamous intraepithelial lesions. American Journal of Reproductive Immunology, 64 (2), 126-136. doi:10.1111/j.1600-0897.2010.00834.x

Jacobs, N., Bartlett, N. W., Clark, R. H., & Smith, G. L. (2008). Vaccinia virus lacking the Bcl-2-like protein N1 induces a stronger natural killer cell response to infection. Journal of General Virology, 89 (Pt 11), 2877-81. doi:10.1099/vir.0.2008/004119-0

Kustermans, G., El Mjiyad, N., Horion, J., Jacobs, N., Piette, J., & Legrand-Poels, S. (2008). Actin cytoskeleton differentially modulates NF-κB-mediated IL-8 expression in myelomonocytic cells. Biochemical Pharmacology, 76(10), 1214-1228. doi:10.1016/j.bcp.2008.08.017

Reschner, A., Hubert, P., Delvenne, P., Boniver, J., & Jacobs, N. (2008). Innate lymphocyte and dendritic cell cross-talk: a key factor in the regulation of the immune response. Clinical and Experimental Immunology, 152 (2), 219-26. doi:10.1111/j.1365-2249.2008.03624.x

Hubert, P., Jacobs, N., Caberg, J.-H., Boniver, J., & Delvenne, P. (October 2007). The cross-talk between dendritic and regulatory T cells: good or evil? Journal of Leukocyte Biology, 82 (4), 781-94. doi:10.1189/jlb.1106694

Delvenne, P., Herman, L., Kholod, N., Caberg, J.-H., Herfs, M., Boniver, J., Jacobs, N., & Hubert, P. (2007). Role of hormone cofactors in the human papillomavirus-induced carcinogenesis of the uterine cervix. Molecular and Cellular Endocrinology, 264 (1-2), 1-5. doi:10.1016/j.mce.2006.10.014

Gubser, C., Goodbody, R., Ecker, A., Brady, G., O'Neill, L. A. J., Jacobs, N., & Smith, G. L. (2007). Camelpox virus encodes a schlafen-like protein that affects orthopoxvirus virulence. Journal of General Virology, 88 (Pt 6), 1667-76. doi:10.1099/vir.0.82748-0

Jacobs, N., Boniver, J., Hubert, P., & Delvenne, P. (2007). Dendritic Cells: More Than Just Adaptive Immunity Inducers? Current Immunology Reviews, 2, 17-22. doi:10.2174/157339507779802214

Zeddou, M., Rahmouni, S., Vandamme, A., Jacobs, N., Frippiat, F., Leonard, P., SCHAAF-LAFONTAINE, N., Vaira, D., Boniver, J., & Moutschen, M. (2007). Downregulation of CD94/NKG2A inhibitory receptors on CD8+ T cells in HIV infection is more pronounced in subjects with detected viral load than in their aviraemic counterparts. Retrovirology, 4, 72. doi:10.1186/1742-4690-4-72

Bindels, S., Mestdagt, M., Van de Walle, C., Jacobs, N., Volders, L., Noël, A., van Roy, F., Berx, G., Foidart, J.-M., & Gilles, C. (17 August 2006). Regulation of vimentin by SIP1 in human epithelial breast tumor cells. Oncogene, 25 (36), 4975-4985. doi:10.1038/sj.onc.1209511

Chen, R. A.-J., Jacobs, N., & Smith, G. L. (2006). Vaccinia virus strain Western Reserve protein B14 is an intracellular virulence factor. Journal of General Virology, 87 (Pt 6), 1451-8. doi:10.1099/vir.0.81736-0

Jacobs, N., Chen, R. A.-J., Gubser, C., Najarro, P., & Smith, G. L. (2006). Intradermal immune response after infection with Vaccinia virus. Journal of General Virology, 87 (Pt 5), 1157-61. doi:10.1099/vir.0.81556-0

Lechanteur, C., Jacobs, N., Greimers, R., Benoit, V., Deregowski, V., Chariot, A., Merville, M.-P., & Bours, V. (03 March 2005). Low daunomycin concentrations protect colorectal cancer cells from hypoxia-induced apoptosis. Oncogene, 24 (10), 1788-1793. doi:10.1038/sj.onc.1208436

Bousarghin, L., Hubert, P., Franzen, E., Jacobs, N., Boniver, J., & Delvenne, P. (2005). Human papillomavirus 16 virus-like particles use heparan sulfates to bind dendritic cells and colocalize with langerin in Langerhans cells. Journal of General Virology, 86 (Pt 5), 1297-305. doi:10.1099/vir.0.80559-0

Hallez, S., Simon, P., Maudoux, F., Doyen, J., Noël, J.-C., Beliard, A., Capelle, X., Buxant, F., Fayt, I., Lagrost, A.-C., Hubert, P., Gerday, C., Burny, A., Boniver, J., Foidart, J.-M., Delvenne, P., & Jacobs, N. (July 2004). Phase I/II trial of immunogenicity of a human papillomavirus (HPV) type 16 E7 protein-based vaccine in women with oncogenic HPV-positive cervical intraepithelial neoplasia. Cancer Immunology, Immunotherapy, 53 (7), 642-650. doi:10.1007/s00262-004-0501-4

Benoit, V., Chariot, A., Delacroix, L., Deregowski, V., Jacobs, N., Merville, M.-P., & Bours, V. (2004). Caspase-8-dependent HER-2 cleavage in response to tumor necrosis factor alpha stimulation is counteracted by nuclear factor kappa B through c-FLIP-L expression. Cancer Research, 64 (8), 2684-2691. doi:10.1158/0008-5472.CAN-03-2914

Delvenne, P., Hubert, P., & Jacobs, N. (2004). Epithelial metaplasia: an inadequate environment for antitumour immunity? Trends in Immunology, 25 (4), 169-73. doi:10.1016/j.it.2004.02.002

Volanti, C., Gloire, G., Vanderplasschen, A., Jacobs, N., Habraken, Y., & Piette, J. (2004). Downregulation of ICAM-1 and VCAM-1 expression in endothelial cells treated by photodynamic therapy. Oncogene, 23 (53), 8649-8658. doi:10.1038/sj.onc.1207871

Remoue, F.* , Jacobs, N.* , Miot, V., Boniver, J., & Delvenne, P. (December 2003). High intraepithelial expression of estrogen and progesterone receptors in the transformation zone of the uterine cervix. American Journal of Obstetrics and Gynecology, 189 (6), 1660-1665. doi:10.1016/S0002-9378(03)00852-4

Delvenne, P., Jacobs, N., Lambert, C., Doyen, J., & Kridelka, F. (May 2003). Le depistage du cancer du col de l'uterus en Belgique: le point en 2003. Revue Médicale de Liège, 58 (5), 316-8.

Bentires-Alj, M., Barbu, V., Fillet, M., Chariot, A., Relic, B., Jacobs, N., Gielen, J., Merville, M.-P., & Bours, V. (2003). NF-κB transcription factor induces drug resistance through MDR1 expression in cancer cells. Oncogene, 22, 90-97. doi:10.1038/sj.onc.1206056

Jacobs, N., Renard, I., Al-Saleh, W., Hubert, P., Doyen, J., Kedzia, W., Boniver, J., & Delvenne, P. (2003). Distinct T cell subsets and cytokine production in cultures derived from transformation zone and squamous intraepithelial lesion biopsies of the uterine cervix. American Journal of Reproductive Immunology, 49 (1), 6-13. doi:10.1034/j.1600-0897.2003.01109.x

Renard, I., Mezzanzanica, D., Canevari, S., Ferrini, S., Boniver, J., Delvenne, P., & Jacobs, N. (January 2002). Anti-CD3/anti-epidermal growth factor receptor-bispecific antibody retargeting of lymphocytes against human neoplastic keratinocytes in an autologous organotypic culture model. American Journal of Pathology, 160 (1), 113-122. doi:10.1016/S0002-9440(10)64355-6

Delvenne, P., Hubert, P., Jacobs, N., Giannini, S., Havard, L., Renard, I., Saboulard, D., & Boniver, J. (2001). The organotypic culture of HPV-transformed keratinocytes: an effective in vitro model for the development of new immunotherapeutic approaches for mucosal (pre)neoplastic lesions. Vaccine, 19 (17-19), 2557-64. doi:10.1016/S0264-410X(00)00489-8

Hubert, P., Giannini, S., Vanderplasschen, A., Franzen-Detrooz, E., Jacobs, N., Boniver, J., & Delvenne, P. (2001). Dendritic cells induce the death of human papillomavirus-transformed keratinocytes. FASEB Journal, 15 (13), 2521-2523. doi:10.1096/fj.00-0872fje

Dejardin, E., Deregowski, V., Chapelier, M., Jacobs, N., Gielen, J., Merville, M.-P., & Bours, V. (22 April 1999). Regulation of Nf-Kappab Activity by I Kappab-Related Proteins in Adenocarcinoma Cells. Oncogene, 18 (16), 2567-77. doi:10.1038/sj.onc.1202599

Jacobs, N., Giannini, S., Al-Saleh, W., Hubert, P., Boniver, J., & Delvenne, P. (1999). Generation of T lymphocytes from the epithelium and stroma of squamous pre-neoplastic lesions of the uterine cervix. Journal of Immunological Methods, 223 (1), 123-9. doi:10.1016/S0022-1759(98)00205-1

Clausse, N., van den Brûle, F., Delvenne, P., Jacobs, N., Franzen-Detrooz, E., Jackers, P., & Castronovo, V. (20 October 1998). Tnf-Alpha and Ifn-Gamma Down-Regulate the Expression of the Metastasis-Associated Bi-Functional 37lrp/P40 Gene and Protein in Transformed Keratinocytes. Biochemical and Biophysical Research Communications, 251 (2), 564-9. doi:10.1006/bbrc.1998.9431

Giannini, S., Al-Saleh, W., Piron, H., Jacobs, N., Doyen, J., Boniver, J., & Delvenne, P. (August 1998). Cytokine Expression in Squamous Intraepithelial Lesions of the Uterine Cervix: Implications for the Generation of Local Immunosuppression. Clinical and Experimental Immunology, 113 (2), 183-9. doi:10.1046/j.1365-2249.1998.00639.x

Jacobs, N., MOUTSCHEN, M., Franzen-Detrooz, E., Boniver, V., Boniver, J., & Delvenne, P. (April 1998). Organotypic Culture of HPV-Transformed Keratinocytes: A Model for Testing Lymphocyte Infiltration of (Pre)Neoplastic Lesions of the Uterine Cervix. Virchows Archiv, 432 (4), 323-30. doi:10.1007/s004280050173

al-Saleh, W., Giannini, S. L., Jacobs, N., Moutschen, M., Doyen, J., Boniver, J., & Delvenne, P. (March 1998). Correlation of T-Helper Secretory Differentiation and Types of Antigen-Presenting Cells in Squamous Intraepithelial Lesions of the Uterine Cervix. Journal of Pathology, 184 (3), 283-90. doi:10.1002/(SICI)1096-9896(199803)184:3<283::AID-PATH25>3.0.CO;2-K

Jacobs, N., Giannini, S. L., Doyen, J., Baptista, A., Moutschen, M., Boniver, J., & Delvenne, P. (January 1998). Inverse Modulation of Il-10 and Il-12 in the Blood of Women with Preneoplastic Lesions of the Uterine Cervix. Clinical and Experimental Immunology, 111 (1), 219-24. doi:10.1046/j.1365-2249.1998.00437.x

Jacobs, N., Mazzoni, A., Mezzanzanica, D., Negri, D. R., Valota, O., Colnaghi, M. I., MOUTSCHEN, M., Boniver, J., & Canevari, S. (July 1997). Efficiency of T Cell Triggering by Anti-Cd3 Monoclonal Antibodies (Mab) with Potential Usefulness in Bispecific Mab Generation. Cancer Immunology, Immunotherapy, 44 (5), 257-64. doi:10.1007/s002620050381

Jacobs, N., Greimers, R., Mazzoni, A., Trebak, M., Schaaf-Lafontaine, N., Boniver, J., & Moutschen, M. (July 1996). Further Characterization of Cytotoxic T Cells Generated by Short-Term Culture of Human Peripheral Blood Lymphocytes with Interleukin-2 and Anti-Cd3 Mab. Cancer Immunology, Immunotherapy, 42 (6), 369-75. doi:10.1007/s002620050296

Greimers, R., Trebak, M., Moutschen, M., Jacobs, N., & Boniver, J. (01 March 1996). Improved Four-Color Flow Cytometry Method Using Fluo-3 and Triple Immunofluorescence for Analysis of Intracellular Calcium Ion ([Ca2+]I) Fluxes among Mouse Lymph Node B- and T-Lymphocyte Subsets. Cytometry, 23 (3), 205-17. doi:10.1002/(SICI)1097-0320(19960301)23:3<205::AID-CYTO4>3.0.CO;2-H

Moutschen, M., Jacobs, N., Hoyoux, C., Martin-Simonet, M.-T., Schaaf-Lafontaine, N., & Boniver, J. (1994). Presence of gd TcR+ Tumor Infiltrating Lymphocytes (TILs) in One Case of Pediatric Osteogenic Sarcoma. International Journal of Pediatric Hematology/Oncology.

Jacobs, N., MOUTSCHEN, M., Boniver, J., Greimers, R., & Schaaf-Lafontaine, N. (February 1993). Efficient Immunoselection of Cytolytic Effectors with a Magnetic Cell Sorter. Research in Immunology, 144 (2), 141-50. doi:10.1016/0923-2494(93)80069-B

Boniver, J., Courtoy, R., Schaaf-Lafontaine, N., Martin-Simonet, M. T., Greimers, R., Rongy, A. M., Moutschen, M., Jacobs, N., Baudrihaye, M., & Delvenne, P. (1992). Cell Surface Receptors in Lymphoid Cells: From Cytochemistry to Molecular Biology and from a Phenotype to a Function. Progress in Histochemistry and Cytochemistry, 26 (1-4), 169-81. doi:10.1016/S0079-6336(11)80093-8

Scientific conferences in universities or research centers

Jacobs, N. (04 July 2019). Le Yin et le Yang de la réponse immunitaire dans les lésions induites par les papillomavirus humains. . Paper presented at 2ème journée Virus & Cancer.

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (23 April 2015). Study of virus-like particules of human papillomavirus (HPV-VLP) by capillary electrophoresis. Paper presented at Séminaire du CIRM.

Scientific congresses and symposiums

Published communications

Renoux, V., Langers Inge, Clémenceau Béatrice, Thiry, M., Antoine, N., Dortu, E., Reschner, A., Boniver, J., Delvenne, P., & Jacobs, N. (2010). Human Papillomavirus Virus-Like particles and NK cell interactions:role of CD16. International Immunology, 22 (suppl Pt 5), 17.

Humblet-Baron, S., CASTERMANS, E., Vanbellinghen, J.-F., Hannon, M., Jacobs, N., WILLEMS, E., Ormenese, S., Beguin, Y., & Baron, F. (February 2009). What Is The Role For Regulatory T-Cells After Nonmyeloablative Conditioning? Biology of Blood and Marrow Transplantation, 15 (2), 122-123. doi:10.1016/j.bbmt.2008.12.377

Humblet-Baron, S., CASTERMANS, E., Vanbellighen, J.-F., Hannon, M., Jacobs, N., Beguin, Y., & Baron, F. (February 2008). What is the Role for Regulatory T-Cells after Nonmyeloablative conditioning. Biology of Blood and Marrow Transplantation, 14 (2), 136-137. doi:10.1016/j.bbmt.2007.12.383

Renoux, V., de Leval, L., Waroux, O., Roncarati, P., Dortu, E., Gathy, R., Arafa, M., Boniver, J., Delvenne, P., & Jacobs, N. (2008). TCRγδ cells in HPV-associated cervical cancer. Acta Clinica Belgica, 63.

Faccinetto, C., Lecut, C., Jacobs, N., Bours, V., & Oury, C. (2007). P2X1 receptors as new regulators of neutrophil life span. Journal of Thrombosis and Haemostasis.

Oral communications or posters

Boclinville, A., Jacobs, N., Thelen, N., Thiry, M., Fillet, M., & Servais, A.-C. (02 February 2022). Interaction studies between HPV-VLP and laminin 332 receptor by affinity capillary electrophoresis. Poster session presented at CIRM Day 2022.

Yazdani, R., Shams-Bakhsh, M., Hassani-Mehraban, A., Arab, S. S., Thelen, N., Thiry, M., Crommen, J., Fillet, M., Jacobs, N., Brans, A., & Servais, A.-C. (September 2020). Characterization of virus-like particles of grapevine fanleaf virus presenting L2 epitope of human papillomavirus minor capsid protein. Poster session presented at 36th International Symposium on Microscale Separations and Bioanalysis (e-MSB 2020).

Arnone, M., Van Hulst, G., Desmet, C., Bureau, F., Jacobs, N., Gerday, S. (Other coll.), HENKET, M. (Other coll.), & LOUIS, R. (Other coll.). (21 May 2019). Building a comprehensive map of immune cell populations in sputum from patients with eosinophilic asthma. Poster session presented at EDT-Immunology day.

Yazdani, R., Shams-Bakhsh, M., Hassani-Mehraban, A., Shahriar Arab, S., Thelen, N., Thiry, M., Crommen, J., Fillet, M., Jacobs, N., Brans, A., & Servais, A.-C. (2019). Characterization of plant virus-based virus-like particles displaying human papillomavirus L2 epitope. Paper presented at 3rd International Symposium on Advances in Pharmaceutical Analysis (APA 2019), Xian, China.

Yazdani, R., Shams-Bakhsh, M., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., Brans, A., & Servais, A.-C. (19 December 2018). Strategies for the study of plant virus-based virus-like particles (VLP) displaying human papillomavirus (HPV) L2 epitope. Poster session presented at 1st CIRM Day, Liège, Belgium.

Bettonville, V., Nicol, J., Furst, T., Thelen, N., Piel, G., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (October 2018). Study of virus-like particles of human papillomavirus in CE. Paper presented at In the framework of High-end Foreign Experts program, Guangzhou, China.

Bettonville, V., Nicol, J., Furst, T., Thelen, N., Piel, G., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (13 July 2018). Strategies for the identification and quantitation of intact virus-like particles of human papillomavirus in CE. Paper presented at 2nd International Symposium on Advances in Pharmaceutical Analysis (APA 2018), Lille, France.

Van hede, D., Polese, B., Humblet, C., Wilharm, A., Renoux, V., DORTU, E., de Leval, L., Delvenne, P., Desmet, C., Bureau, F., Vermijlen, D., & Jacobs, N. (June 2018). Human papillomavirus oncoproteins induce a reorganization of epithelial-associated γδ T cells promoting tumor formation. Poster session presented at Gamma delta conferance, Bordeaux, France.

Bettonville, V., Nicol, J., Furst, T., Thelen, N., Piel, G., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (15 March 2018). Analyse de pseudo-particules virales intactes de papillomavirus humain par électrophorèse capillaire : stratégies pour l’identification et la quantification. Paper presented at Analytics & Biologics : de la cellule à la petite molécule ?.

Bettonville, V., Nicol, J., Furst, T., Thelen, N., Piel, G., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (19 September 2017). Identification and quantitation of intact virus-like particles of human papillomavirus (HPV-VLP) using capillary electrophoresis. Paper presented at CE Pharm 2017.

Bettonville, V., Nicol, J., Furst, T., Thelen, N., Piel, G., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (March 2017). Strategies for the identification and quantitation of virus-like particles of human papillomavirus using capillary electrophoresis. Poster session presented at Analytical Technologies Europe 2017.

Bettonville, V., Nicol, J., Furst, T., Thelen, N., Piel, G., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (2017). Study of virus-like particles of human papillomavirus in capillary electrophoresis. Poster session presented at 33rd International Symposium on Microscale Separations and Bioanalysis (MSB 2017), Noordwijkerhout, Netherlands.

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (14 November 2016). Quantitation and biospecific identification of virus-like particles of human papillomavirus using capillary electrophoresis. Paper presented at 27th International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2016), Guangzhou, China.

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (28 September 2016). Stratégies pour l'identification et la quantification de pseudo-particules virales de papillomavirus humain par électrophorèse capillaire. Paper presented at 9èmes journées scientifiques de l'Association Francophone pour l'étude des Infections à Papillomavirus et Polyomavirus.

Van hede, D., Renoux, V., DORTU, E., Langers, I., Vermijlen, D., & Jacobs, N. (June 2016). Human papillomavirus induces a reorganization of epidermal- associated γδ T cells and promote tumour formation. Poster session presented at Gamma Delta Conference 2016.

Van hede, D., Francis, F., ARRESE ESTRADA, J., Gau Okroglic, A., Moline, S., Renoux, V., Dortu, E., Langers, I., DELVENNE, P., Vermijlen, D., & Jacobs, N. (03 December 2015). Gamma delta T cells promote cancer progression in a murine model of human papillomavirus-induced lesions. Poster session presented at Séminaire Télévie 2016, Gembloux, Belgium.

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (08 September 2015). Analysis of intact virus-like particles of human papillomavirus (HPV-VLP) in capillary electrophoresis. Poster session presented at UniGR workshop: from drug target to drug development.

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (July 2015). Characterization of intact virus-like particles of human papillomavirus 16 (HPV16-VLP) in capillary electrophoresis. Paper presented at 26th International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2015), Tbilisi, Georgia.

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (24 June 2015). Analysis of intact virus-like particles of human papillomavirus (HPV-VLP) in capillary electrophoresis. Paper presented at HPLC 2015.

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (28 May 2015). Capillary electrophoretic analysis of intact virus-like particles of human papillomavirus (HPV-VLP). Paper presented at 18th Forum of Pharmaceutical Sciences.

Van hede, D., Francis, F., ARRESE ESTRADA, J., Gau Okroglic, A., Moline, S., Renoux, V., Dortu, E., Langers, I., Delvenne, P., Vermijlen, D., & Jacobs, N. (11 February 2015). Dermal γδ T cells could promote cancer progression of HPV-induced lesions via pro-angiogenic mechanisms. Poster session presented at Séminaire Télévie 2015.

Bettonville, V., Bastin, R., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (25 June 2014). Study of virus-like particles of human papillomavirus (HPV-VLP) by capillary electrophoresis. Paper presented at Drug Analysis 2014.

Van hede, D., Bastin, R., Francis, F., ARRESE ESTRADA, J., Gau Okroglic, A., Renoux, V., Dortu, E., Langers, I., DELVENNE, P., Vermijlen, D., & Jacobs, N. (18 May 2014). γδ T cells could promote cancer progression of HPV-induced lesions via pro-angiogenic mechanisms. Poster session presented at 6ème Congrès sur les lymphocytes T Gamma Delta.

Renoux, V., Bisig, B., Langers, I., Bastin, R., Thiry, M., Deroanne, C., Delvenne, P., & Jacobs, N. (May 2013). Human papillomavirus entry into NK cells requires CD16 expression and triggers cytotoxic activity and cytokine secretion. Poster session presented at Gordon Conference Virus & Cell, Lucca, Italy.

Renoux, V., Langers, I., Dortu, E., Bisig, B., Thiry, M., Deroanne, C., Boniver, J., Delvenne, P., & Jacobs, N. (28 January 2013). Human papillomavirus entry into NK cells requires CD16 expression and triggers cytotoxic activity and cytokine secretion. Paper presented at GIGA-Day, Liège, Belgium.

Van hede, D., Bastin, R., Francis, F., Bisig, B., Arrese Estrada, J., Renoux, V., Dortu, E., Langers, I., Delvenne, P., Vermijlen, D., & Jacobs, N. (28 January 2013). Role of Gamma Delta T cells in HPV-induced Cancer Progression. Poster session presented at Giga Day 2013.

Brohée, L., Bastin, R., Wingert, S., Netter, P., Waltz, C., Delvenne, P., & Jacobs, N. (2013). Expansion of CD16+ CD56+ NK cells in vericyte® NK cell growth medium. Poster session presented at 14th Meeting of the Society for Natural Immunity, Heidelberg, Germany.

EL SHAZLY, A., Castillo-Doloriert, H., Bisig, B., LEFEBVRE, P., Delvenne, P., & Jacobs, N. (2013). Novel cooperation between CX3CL1 and CCL26 inducing NK cell chemotaxis via CX3CR1: a possible mechanism for NK cell infiltration of the allergic nasal tissue. Poster session presented at 14th Meeting of the Society for Natural Immunity, Heidelberg, Germany.

Renoux, V., Bastin, R., Boniver, J., Delvenne, P., Jacobs, N., Langers, I. (Other coll.), Dortu, E. (Other coll.), Deroanne, C. (Other coll.), & Clémenceau, B. (Other coll.). (10 December 2012). Oncogenic human papillomavirus could directly interact with Natural Killer cells. Poster session presented at Séminaire des chercheurs Télévie 2013.

Van hede, D., Bastin, R., Francis, F., Bisig, B., Arrese Estrada, J., Renoux, V., Dortu, E., Langers, I., Delvenne, P., & Jacobs, N. (10 December 2012). Role of γδ T cells in HPV-induced cancer progression. Poster session presented at Séminaire des chercheurs Télévie 2013.

Van hede, D., Bastin, R., Francis, F., Bisig, B., Arrese Estrada, J., Renoux, V., Dortu, E., Langers, I., Delvenne, P., Vermijlen, D., & Jacobs, N. (09 November 2012). Role of γδ T cells in the tumoural progression of HPV-associated lesions. Paper presented at Giga Cancer Seminar.

Langers, I., Renoux, V., Pirotte, E., Dortu, E., BONIVER, J., DELVENNE, P., & Jacobs, N. (26 September 2012). Human papillomavirus capsids trigger crosstalk between dendritic and NK cells. Poster session presented at Natural Killer Cell Symposium 2012, Heidelberg, Germany.

Langers, I., Renoux, V., Dortu, E., Delvenne, P., & Jacobs, N. (22 June 2012). The human papillomavirus (HPV) vaccine induces collaboration between dendritic cells and natural killer cells in vitro. Paper presented at Giga Cancer Day, Liège, Belgium.

Renoux, V., Bastin, R., Boniver, J., Delvenne, P., Jacobs, N., Langers, I. (Other coll.), Dortu, E. (Other coll.), Deroanne, C. (Other coll.), & Clémenceau, B. (Other coll.). (22 June 2012). Oncogenic human papillomavirus could directly interact with Natural Killer cells. Poster session presented at Giga Cancer Day.

Van hede, D., Bastin, R., Francis, F., Bisig, B., Arrese Estrada, J., Renoux, V., Dortu, E., Langers, I., Delvenne, P., Vermijlen, D., & Jacobs, N. (22 June 2012). Role of γδ T cells in HPV-induced cancer progression. Poster session presented at Giga Cancer Day 2012.

Van hede, D., Bastin, R., Francis, F., Bisig, B., Arrese Estrada, J., Renoux, V., Dortu, E., Langers, I., Boniver, J., Delvenne, P., Vermijlen, D., & Jacobs, N. (02 June 2012). γδ T cells could promote cancer progression of HPV-induced lesions. Paper presented at Fifth International Gamma-Delta T-Cell Conference Freiburg 2012, Freiburg, Germany.

Langers, I., Renoux, V., Dortu, E., Delvenne, P., & Jacobs, N. (04 May 2012). The human papillomavirus vaccine induces collaboration between dendritic cells and natural killer cells in vitro. Poster session presented at Giga day, Liège, Belgium.

Renoux, V., Bastin, R., Boniver, J., Delvenne, P., Jacobs, N., Langers, I. (Other coll.), Dortu, E. (Other coll.), Deroanne, C. (Other coll.), Thiry, M. (Other coll.), & Clémenceau, B. (Other coll.). (04 May 2012). Oncogenic human papillomavirus could directly interact with Natural Killer cells. Poster session presented at Giga day.

Renoux, V., Bastin, R., Langers, I., Bisig, B., Dortu, E., Clémenceau, B., Thiry, M., Deroanne, C., Boniver, J., Delvenne, P., & Jacobs, N. (28 March 2012). Human papillomavirus entry triggers NK cell cytotoxic activity and cytokine secretion. Poster session presented at Keyston symposia, Whistler, Canada.

Van hede, D., Bastin, R., Francis, F., Bisig, B., Arrese Estrada, J., Renoux, V., Dortu, E., Langers, I., BONIVER, J., DELVENNE, P., & Jacobs, N. (04 February 2012). γδ T cells could promote cancer progression of HPV-induced lesions. Paper presented at BACR meeting 2012, Bruxelles, Belgium.

Renoux, V., Bastin, R., Langers, I., Dortu, E., Deroanne, C., Thiry, M., Clémenceau, B., Boniver, J., Delvenne, P., & Jacobs, N. (2012). Oncogenic human papillomavirus could directly interact with natural killer cells. Poster session presented at GIGA-DAY.

Renoux, V., Langers, I., Clémenceau, B., Thiry, M., Bisig, B., Deroanne, C., Dortu, E., Boniver, J., Delvenne, P., & Jacobs, N. (13 September 2011). Macropinocytosis of human papillomaviruses in natural killer cells via CD16 induces cytotoxic granule exocytosis and cytokine secretion. Poster session presented at IUMS International Congress of Virology, Sapporo, Japan.

Jacobs, N., Renoux, V., Bisig, B., Langers, I., Dortu, E., Clémenceau, B., Thiry, M., Deroanne, C., Boniver, J., & Delvenne, P. (2011). HPV triggers NK cell cytotoxic activity and cytokine secretion. Paper presented at 27th International Papillomavirus Conference, Berlin, Germany.

Renoux, V., Langers, I., Clémenceau, B., Thiry, M., Bisig, B., Deroanne, C., Dortu, E., Boniver, J., Delvenne, P., & Jacobs, N. (2011). Macropinocytosis of human papillomaviruses in natural killer cells via CD16 induces cytotoxic granule exocytosis and cytokine secretion. Poster session presented at GIGA-Day.

Langers, I., Reschner, A., Renoux, V., Dortu, E., BONIVER, J., DELVENNE, P., & Jacobs, N. (December 2010). Vaccine against human papillomavirus (HPV)-associated lesions induces collaboration between natural killer and dendritic cells in vitro. Poster session presented at Annual Congress: New frontiers in dendritic cell biology, Paris, France.

Langers, I., Renoux, V., Reschner, A., Dortu, E., Boniver, J., Delvenne, P., & Jacobs, N. (30 January 2010). Cross talk between dendritic and natural killer cells in the presence of vaccine agent against cervical cancer. Paper presented at ABEC- Annual meeting of the Belgian Association for Cancer Research, Leuven, Belgium.

Renoux, V., Langers, I., Reschner, A., Dortu, E., Clémenceau, B., Suarez-Carmona, M., Thiry, M., Boniver, J., Delvenne, P., & Jacobs, N. (November 2009). Influence of the vaccine agent of uterine cervical cancer on the crosstalk between Natural Killer and Dendritic Cells. Poster session presented at Natural killer symposium, Freiburg, Germany.

Renoux, V., Bisig, B., Thiry, M., Arafa, M. M. M., Willems, J., Dortu, E., Boniver, J., de Leval, L., Delvenne, P., & Jacobs, N. (2009). Innate lymphocytes in human papillomavirus (HPV)-associated cervical cancers. Poster session presented at GIGA-Cancer Day.

Renoux, V., Bisig, B., Thiry, M., Dortu, E., Boniver, J., de Leval, L., Delvenne, P., & Jacobs, N. (2009). Innate lymphocytes in human papillomavirus (HPV)-associated cervical cancers. Poster session presented at Télévie 2009, Liège, Belgium.

Renoux, V., Dortu, E., Langers, I., Reschner, A., Longton, L., Boniver, J., Delvenne, P., & Jacobs, N. (2009). Interaction between dendritic cells and natural killer cells in vaccination against cervical cancer. Paper presented at ABEC - Annual meeting of the Belgian Association for Cancer Research, Bruxelles, Belgium.

Renoux, V., Reschner, A., Langers, I., Willems, J., Dortu, E., Boniver, J., Delvenne, P., & Jacobs, N. (2009). Interaction between Natural Killer and dendritic cells in the presence of vaccine agent of uterine cervical cancer. Poster session presented at 2nd European Congress of Immunology, Berlin, Germany.

Renoux, V., Dortu, E., Boniver, J., Delvenne, P., & Jacobs, N. (2008). Interaction between uterine cervical cancer vaccine and innate immune cells. Paper presented at British Society for Immunology Congress 2008, Glasgow, United Kingdom.

Renoux, V., Dortu, E., Provenzano, F., Longton, L., Boniver, J., Delvenne, P., & Jacobs, N. (2008). Interaction between virus like particles (VLP) and natural killer (NK) cells. Paper presented at ABEC - Annual meeting of the Belgian Association for Cancer Research, Bruxelles, Belgium.

Renoux, V., Longton, L., Dortu, E., Boniver, J., Delvenne, P., & Jacobs, N. (11 October 2007). Interaction between the vaccine of cervical cancer associated and natural killer (NK) cells. Poster session presented at Bioforum, Liège, Belgium.

Renoux, V., Longton, L., Dortu, E., Boniver, J., Delvenne, P., & Jacobs, N. (10 October 2007). Interaction between human papillomavirus (HPV) and natural killer (NK) cells. Paper presented at « 6th Workshop "Immunobiology of viral infection of the German Society of Virology », Deidesheim, Germany.

Renoux, V., Dortu, E., Herman, L., Rahmouni, S., Boniver, J., Delvenne, P., & Jacobs, N. (01 June 2007). NK Cells Interact With virus–like particles (VLP) of human papillomavirus (HPV). Paper presented at Journées du Centre de recherche en cancérologie expérimentale (CRCE), Liege, Belgium.

Renoux, V., Dortu, E., Herman, L., Boniver, J., Delvenne, P., & Jacobs, N. (25 April 2007). NK CELLS and virus–like particle (VLP) of human papillomavirus (HPV). Paper presented at Journée de l'Action Coordonnée 31 (AC31) sur le thème "NK cells, HIV and Hepatitis", Paris, France.

Jacobs, N., Renoux, V., Dortu, E., Arafa, M., de Leval, L., Roncarati, P., Boniver, J., & Delvenne, P. (12 April 2007). NK CELLS AND NKG2D LIGANDS IN HPV-ASSOCIATED CERVICAL CANCER. Poster session presented at 10th Meeting of the Society for Natural Immunity, Cambridge, United Kingdom.

Hubert, P., Doyen, J., Chapelle, X., Evrard, B., Gerday, C., Boniver, J., Foidart, J.-M., & Jacobs, N. (2007). Phase I/IIclinical trial of local GM-CSF application in patients with cervical HPV-associated low grade squamous intraepithelial lesions. Paper presented at 24th International Papillomavirus Conference and Clinical Workshops, Bejing, China.

Jacobs, N., & Delvenne, P. (2007). Experimental models/cell model: organotypic cultures. Paper presented at HPV and Skin Cancer 4th International Meeting, Besançon, France.

Bindels, S., Mestdagt, M., Vandewalle, C., Jacobs, N., Volders, L., Noël, A., Van Roy, F., Berx, G., Foidart, J.-M., & Gilles, C. (22 June 2006). Regulation of vimentin by SIP-1 in human epithelial breast tumor cells. Poster session presented at BRECOSM Breast Cancer and metastasis Conference, Paris, France.

Bindels, S., Mestdagt, M., Vandewalle, C., Jacobs, N., Volders, L., Noël, A., Van Roy, F., Berx, G., Foidart, J.-M., & Gilles, C. (08 June 2006). Regulation of vimentin by SIP1 in human epithelial breast tumor cells. Poster session presented at Journées du CRCE, Liège, Belgium.

Bindels, S., Mestdagt, M., Vandewalle, C., Jacobs, N., Volders, L., Noël, A., Van Roy, F., Berx, G., Foidart, J.-M., & Gilles, C. (01 April 2006). Regulation of vimentin by SIP-1 in human epithelial breast tumor cells. Poster session presented at Annual meeting of the American Association for Cancer Research (AACR), Washington, United States.

Delanaye, L., Volanti, C., Jacobs, N., Greimers, R., Bahri, M. A., Hoebeke, M., & Piette, J. (2005). Study in human colon cancer cells HCT-116 of PPME photodynamic effect solubilized in DMPC liposomes. Paper presented at General Congress of the SFP and BPS, Lille, France.

Delanaye, L., Volanti, C., Jacobs, N., Greimers, R., Bahri, M. A., Hoebeke, M., & Piette, J. (2005). Improvement by solubilization in DMPC liposomes of PPME photodynamic effect - A study in human colon cancer cells HCT-116. Paper presented at 11th Congress of the European Society for Photobiology, Aix-les-Bains, France.

Delanaye, L., Volanti, C., Jacobs, N., Greimers, R., Fontaine-Aupart, M.-P., Vanderplasschen, A., Hoebeke, M., & Piette, J. (2004). Improvement by solubilization in DMPC liposomes of PPME photodynamic effect - A study in human colon cancer cells HCT-116. Paper presented at 187th meeting of the Belgian Society of Biochemistry and Molecular Biology, Liège, Belgium.

Book chapters and contributions to collective works

Reschner, A., Langers, I., Renoux, V., Delvenne, P., & Jacobs, N. (2010). Regulation of the Immune Response by Innate Lymphocyte and Dendritic Cell Cross Talk. In L. Welles (Ed.), Dendritic Cells: Types, Life Cycles and Biological Functions. Nova Science Publishers, Inc.

Delvenne, P., Hubert, P., Havard, L., Renard, I., Boniver, J., & Jacobs, N. (2003). Modèles expérimentaux in vitro des HPV. In F. Aubin, J. F. Pretet, & C. Mougin, Papillomavirus Humains (pp. 75-101). Paris, France: Tec & Doc.

Jacobs, N., Renard, I., Pisvin, S., Hubert, P., Boniver, J., & Delvenne, P. (2000). IL10 production in cultures of lymphocytes derived from biopsies of normal exocervix, transformation zone and squamous intraepithelial lesion. In J. Monsonego (Ed.), 4th International Multidisciplinary Congress - Eurogin 2000 (pp. 355-362). Pianoro, Italy: International Proceedings Division, Monduzzi Editore.

Theses and dissertations

Doctoral thesis

Jacobs, N. (1996). Caractérisation des lymphocytes stimulés par l'interleukine-2 et un anticorps anti-CD3 dans une perspective de thérapie anti tumorale. Unpublished doctoral thesis, ULiège - Université de Liège.
Jury: .

Other publications and communications

Articles in scientific journals without peer reviewing

Delvenne, P., Goffin, F., Kridelka, F., Arafa, M., Caberg, J.-H., Herfs, M., Herman, L., Hubert, P., Jacobs, N., Kholod, N., Boniver, J., & Foidart, J.-M. (2007). Le cancer du col de l'utérus: du virus au traitement. Revue Médicale de Liège, 62(S1), 2-6.

Speeches and writings for a general audience

General audience and popularisation articles

Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., & Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique.

Others

Van hede, D., & Jacobs, N. (2013). Cancer du col de l’utérus: Diagnostic, prévention et thérapies.