Publications of Céline Bellefroid
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See detailMetformin-Induced Lactic Acidosis : A question of Time
Bellefroid, Céline ULiege; Goffin, Pierre; Guntz, Julien et al

in Case Reports in Critical Care (2020)

Metformin is an oral antidiabetic largely prescribed in the treatment of type II diabetes. Overdose is associated with life-threatening lactic acidosis. We report the case of the highest metformin ... [more ▼]

Metformin is an oral antidiabetic largely prescribed in the treatment of type II diabetes. Overdose is associated with life-threatening lactic acidosis. We report the case of the highest metformin concentration ever described secondary to a voluntary suicidal intake. The patient developed a severe lactic acidosis and hemodynamic shock successfully treated with high-flow hemofiltration. Time to start extrarenal epuration is capital to avoid poor evolution. [less ▲]

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