Publications of Christophe MILANTS
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See detailÉtude de l'excitabilité axonale périphérique : comment et pourquoi ?
Thyberghein, Maelle; MILANTS, Christophe ULiege; WANG, François-Charles ULiege

in ENMG 2020 (2020)

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See detailLe pied tombant
WANG, François-Charles ULiege; MILANTS, Christophe ULiege

Conference (2019, November 30)

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See detailLes neuropathies d’origine mécanique du coude
Kaux, Jean-François ULiege; MILANTS, Christophe ULiege; WANG, François-Charles ULiege

Conference (2019, May 28)

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See detailResponders to Platelet-Rich Plasma in Osteoarthritis: A Technical Analysis
MILANTS, Christophe ULiege; Bruyère, Olivier ULiege; Kaux, Jean-François ULiege

in Back to rehab, rehab for back (2018, December 07)

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See detailToxicité aigüe de l'oxaliplatine
WANG, François-Charles ULiege; MILANTS, Christophe ULiege

Scientific conference (2018, October 02)

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See detailKNEE OSTEOARTHRITIS AND PLATELET-RICH PLASMA TREATMENT : HOW TO IMPROVE THE EFFICIENCY ?
MILANTS, Christophe ULiege; Bruyère, Olivier ULiege; Kaux, Jean-François ULiege

in 12th International Society of Physical and Rehabilitation Medicine World Congress (2018, July)

Introduction/Background The management of chondral disease is challenging. New studies have focused on modern therapeutic methods that stimulate cartilage healing process and improve the damage, including ... [more ▼]

Introduction/Background The management of chondral disease is challenging. New studies have focused on modern therapeutic methods that stimulate cartilage healing process and improve the damage, including the use of platelet-rich plasma (PRP). PRP is prepared from autologous blood by centrifugation to obtain a highly concentrated sample of platelets. Due to the mixed results from controlled studies, the clinical efficacy of PRP in the treatment of knee OA is unclear with shortcomings in the current literature. Material and Method A comparison of the outcomes of randomized controlled trials (RCTs) included in the 3 most recent and high-quality meta-analyses to classify the different studies in 2 groups (bad responders group (BRG) and very good responders group (VGRG)). The minimal clinically important improvement (MCII) was defined to help determining whether an observed difference is clinically important. We used MCII values to classify the different studies in 2 groups depending on the outcomes: BRG < MCII and VGRG > 2xMCII. Results From the 19 RCTs analyzed, 7 trials were included in the VGRG and 4 in the BRG. In VGRG, 1 or 2 injections were performed in 4/7 trials, time between injections was 2 to 3 weeks in 4/5 studies with many injections, volume injected varied from 2.5 to 8 mL, and single spinning technique was used in 5/7 studies. PRP classification was Mishra 4B and PAWP2Bβ in 5/7 studies. The use of PRP with leukocytes is only found in the BRG. Conclusion Our study helped identify features of PRP recommended for knee OA treatment, such as the use of a single spinning technique, a platelet concentration lower than 5 times the baseline (from 3 to 4), and avoiding leukocytes and erythrocytes. We recommend leveraging this information about PRP for future studies. [less ▲]

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See detailResponders to Platelet-Rich Plasma in Osteoarthritis: A Technical Analysis
MILANTS, Christophe ULiege; Bruyère, Olivier ULiege; Kaux, Jean-François ULiege

in abstract Book - 21st European Congress of Physical and Rehabilitation Medicine (2018, May)

Introduction: Platelet-rich plasma (PRP) is more and more used in musculoskeletal condition such as osteo-arthritis. Propose: To evaluate the similarities and differences between the variety of platelet ... [more ▼]

Introduction: Platelet-rich plasma (PRP) is more and more used in musculoskeletal condition such as osteo-arthritis. Propose: To evaluate the similarities and differences between the variety of platelet-rich plasma (PRP) formulations, preparation, and uses to try to determine the best responses for the treatment of knee osteoarthritis. Materials and Methods. A comparison of the outcomes of randomized controlled trials (RCTs) included in the 3 most recent and high-quality meta-analyses to classify the different studies in 2 groups (bad responders group (BRG) and very good responders group (VGRG)). Results and Discussion:From the 19 RCTs analyzed, 7 trials were included in the VGRG and 4 in the BRG. In VGRG, 1 or 2 injections were performed in 4/7 trials, time between injections was 2 to 3 weeks in 4/5 studies with many injections, volume injected varied from 2.5 to 8 mL, and single spinning technique was used in 5/7 studies. PRP classification was Mishra 4B and PAWP2B𝛽 in 5/7 studies. The use of PRP with leukocytes is only found in the BRG. Conclusion. There is a lack of standardization in PRP preparation technique for knee osteoarthritis. However it appears that the use of a single spinning technique, a platelet concentration lower than 5 times the baseline, and avoidance of leukocytes should be preferred. [less ▲]

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See detailKNEE OSTEOARTHRITIS AND PLATELET-RICH PLASMA TREATMENT: HOW TO IMPROVE THE EFFICIENCY?
MILANTS, Christophe ULiege; Bruyère, Olivier ULiege; Kaux, Jean-François ULiege

in Osteoporosis International (2018, April), 29(Supplement 1), 380

Introduction: Knee osteoarthritis (OA) is one of the major causes of pain and physical disability in older sportsmen. The management of chondral disease is challenging because of its inherent low healing ... [more ▼]

Introduction: Knee osteoarthritis (OA) is one of the major causes of pain and physical disability in older sportsmen. The management of chondral disease is challenging because of its inherent low healing potential. New studies have focused on modern therapeutic methods that stimulate cartilage healing process and improve the damage, including the use of platelet-rich plasma (PRP), an autologous growth factor treatment. PRP is prepared from autologous blood by centrifugation to obtain a highly concentrated sample of platelets, which is four to five times higher than that of normal blood. Many papers were published on PRP for knee OA, including a lot of randomized controlled trials (RCTs) and different systematic reviews. Due to the mixed results from controlled studies, the clinical efficacy of PRP in the treatment of knee OA is unclear with shortcomings in the current literature. Purpose: The objective of this study was to evaluate the similarities and differences between the variety of PRP formulations, preparation, and uses of this techniques in literature and to try to determine characteristics of the PRP which tend to give the best responses for the treatment of knee osteoarthritis.. Methods: A comparison of the outcomes of randomized controlled trials (RCTs) included in the 3 most recent and high-quality metaanalyses to classify the different studies in 2 groups (bad responders group (BRG) and very good responders group (VGRG)). The minimal clinically important improvement (MCII) was defined to help determining whether an observed difference is clinically important. We used MCII values to classify the different studies in 2 groups depending on the outcomes: BRG < MCII and VGRG > 2xMCII. Results: From the 19 RCTs analyzed, 7 trials were included in the VGRG and 4 in the BRG. In VGRG, 1 or 2 injections were performed in 4/7 trials, time between injections was 2 to 3 weeks in 4/5 studies with many injections, volume injected varied from 2.5 to 8 mL, and single spinning technique was used in 5/7 studies. PRP classification was Mishra 4B and PAWP2Bβ in 5/7 studies. The use of PRP with leukocytes is only found in the BRG. Conclusion: There is a lack of standardization in PRP preparation technique for knee osteoarthritis. However, our study helped identify features of PRP recommended for knee OA treatment, such as the use of a single spinning technique, a platelet concentration lower than 5 times the baseline (from 3 to 4), and avoiding leukocytes and erythrocytes. We recommend leveraging this information about PRP for future studies. [less ▲]

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See detailiMAX: a new tool to assess peripheral motor axonal hypoexcitability
MILANTS, Christophe ULiege; BENMOUNA, Karim ULiege; WANG, François-Charles ULiege

in Clinical Neurophysiology (2017), 128(12), 2382-3

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See detailResponders to platelet-rich plasma (PRP) in osteoarthritis: A technical analysis
MILANTS, Christophe ULiege; Bruyère, Olivier ULiege; Kaux, Jean-François ULiege

in BioMed Research International (2017)

Purpose. To evaluate the similarities and differences between the variety of platelet-rich plasma (PRP) formulations, preparation, and uses to try to determine the best responses for the treatment of knee ... [more ▼]

Purpose. To evaluate the similarities and differences between the variety of platelet-rich plasma (PRP) formulations, preparation, and uses to try to determine the best responses for the treatment of knee osteoarthritis. Materials and Methods. A comparison of the outcomes of randomized controlled trials (RCTs) included in the 3 most recent and high-quality meta-analyses to classify the different studies in 2 groups (bad responders group (BRG) and very good responders group (VGRG)). Results and Discussion. From the 19 RCTs analyzed, 7 trials were included in the VGRG and 4 in the BRG. In VGRG, 1 or 2 injections were performed in 4/7 trials, time between injections was 2 to 3 weeks in 4/5 studies with many injections, volume injected varied from 2.5 to 8 mL, and single spinning technique was used in 5/7 studies. PRP classification was Mishra 4B and PAWP2B𝛽 in 5/7 studies. The use of PRP with leukocytes is only found in the BRG. Conclusion. There is a lack of standardization in PRP preparation technique for knee osteoarthritis. However it appears that the use of a single spinning technique, a platelet concentration lower than 5 times the baseline, and avoidance of leukocytes should be preferred. [less ▲]

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See detailMUNIX vs TASPM
BENMOUNA, Karim ULiege; MILANTS, Christophe ULiege; WANG, François-Charles ULiege

Poster (2017, June 27)

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See detailLes Nodo/Paranodopathies
MILANTS, Christophe ULiege

Conference (2017, June 06)

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See detailScapulothoracic bursitis and kyphoscoliosis: a case report
MILANTS, Christophe ULiege; Kaux, Jean-François ULiege

in Abstract Book of Annual Congress of Physical & Rehabilitation Medicine 2016 (2016, December 09)

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See detailLe syndrome tarsien antérieur
MILANTS, Christophe ULiege; WANG, François-Charles ULiege; Gomulinski, Léon et al

in Revue Médicale de Liège (2015), 70(7-8), 400-404

The anterior tarsal tunnel syndrome is a rare entrapment neuropathy of the deep peroneal nerve beneath the inferior extensor retinaculum of the ankle. It is unrecognized and may lead to misdiagnosis and ... [more ▼]

The anterior tarsal tunnel syndrome is a rare entrapment neuropathy of the deep peroneal nerve beneath the inferior extensor retinaculum of the ankle. It is unrecognized and may lead to misdiagnosis and delayed treatment. We report the case of a 77 years old patient complaining of anterior tarsal tunnel syndrome’s symptoms with neuropathic pain located at the dorsal part of the foot without any sensorimotor loss. The electroneuromyography was in favour of the motor impairment of the deep peroneal nerve. MRI exploration of the ankle showed a millimetric bony overgrowth of the upper pole of the navicular irritative to the deep peroneal nerve. Infiltration at overgrowth of the navicular provided a partial and temporary decrease in pain symptoms. Surgical nerve decompression was then considered. [less ▲]

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