Publications of Romy GADISSEUR
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See detailNouvelles perspectives cliniques avec ImmunoCAP ISAC
GADISSEUR, Romy ULiege

Conference (2020, February 20)

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See detailNew approaches to manage hymenoptera venom allergic patients at risk of anaphylaxis
GADISSEUR, Romy ULiege

Conference (2019, December 14)

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See detailAllergies croisées crustacés et insectes comestibles
GADISSEUR, Romy ULiege

Conference (2019, December 14)

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See detailRisk of allergenic transmissions linked to human insect consumption
GADISSEUR, Romy ULiege

Scientific conference (2019, December 03)

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See detailGood Clinical Practice for in-vitro diagnosis of food allergy
GADISSEUR, Romy ULiege

Conference (2019, September 21)

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See detailWEBINAR Intérêt de la puce ImmunoCAP ISAC
GADISSEUR, Romy ULiege

in GADISSEUR, Romy (Ed.) Intérêt de la puce ImmunoCAP ISAC (2019)

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See detailBetula verrucosa may be taken as a marker allergen for Tx5 tree mix
GADISSEUR, Romy ULiege; LUKAS, Pierre ULiege; Cavalier, Etienne ULiege

in Allergy (2019, June 03), 74(106), 130-331

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See detailPhleum pratense may be taken as a marker allergen for Gx3 grass mix
GADISSEUR, Romy ULiege; LUKAS, Pierre ULiege; Cavalier, Etienne ULiege

in Allergy (2019, June 03), 74(106), 101-331

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See detailProfil de sensibilisation de patients allergiques au sein d'une population entomophage à Niamey au Niger
GADISSEUR, Romy ULiege; Hamidou, Tahirou

Poster (2019, April 17)

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See detailRaman chemical imaging, a new tool in kidney stone structure analysis: Case-study and comparison to Fourier Transform Infrared spectroscopy
Castiglione, Vincent ULiege; Sacre, Pierre-Yves ULiege; Cavalier, Etienne ULiege et al

Poster (2018, November 16)

The kidney stone’s structure might provide clinical information in addition to the stone composition. The Raman chemical imaging is a technology used for the production of two- dimension maps of the ... [more ▼]

The kidney stone’s structure might provide clinical information in addition to the stone composition. The Raman chemical imaging is a technology used for the production of two- dimension maps of the constituents’ distribution in samples. We aimed at determining the use of Raman chemical imaging in urinary stone analysis. Fourteen calculi were analyzed by Raman chemical imaging using a confocal Raman micro- spectrophotometer. They were selected according to their heterogeneous composition and morphology. Raman chemical imaging was performed on the whole section of stones. Once acquired, the data were baseline corrected and analyzed by MCR-ALS. Results were then compared to the spectra obtained by Fourier Transform Infrared spectroscopy. [less ▲]

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See detailClinical data on rare Sulfamethoxazole crystalluria assessed by Fourier Transform Infrared Spectrophotometry
CASTIGLIONE, Vincent ULiege; CAVALIER, Etienne ULiege; GADISSEUR, Romy ULiege

in Data in Brief (2018)

The data contained in this article are related to the article entitled “Case report: Uncommon Sulfamethoxazole Crystalluria” [1]. Sulfamethoxazole crystalluria is very rare and crystals identification is ... [more ▼]

The data contained in this article are related to the article entitled “Case report: Uncommon Sulfamethoxazole Crystalluria” [1]. Sulfamethoxazole crystalluria is very rare and crystals identification is complex [2], [3]. We identified seven patients with uncommon urine crystals that were composed of N-Acetyl-Sulfamethoxazole. Three of the patients developed an acute renal failure simultaneously to crystalluria. Hence, this article describes the method of crystals identification thanks to infrared spectroscopy. The relevant clinical data of patients, including medical history, drug dosage and urine parameters related to the crystalluria are presented. [less ▲]

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See detailIntérêt du dosage de la tryptase dans un service d'urgences
GADISSEUR, Romy ULiege

Scientific conference (2018, October 17)

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See detailUrine sediment analysis: comparison of three automated analyzers
Castiglione, Vincent ULiege; GADISSEUR, Romy ULiege

Conference (2018, October 09)

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See detailComment j'explore...Une protéinurie
Résimont, Guillaume ULiege; GADISSEUR, Romy ULiege; LUTTERI, Laurence ULiege et al

in Revue Médicale de Liège (2018), 73(10), 519-525

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See detailValidation of 24 blood gas analyzers, GEM 5000 Premier
GADISSEUR, Romy ULiege; MUSSO, Giuseppe ULiege; Cavalier, Etienne ULiege et al

Poster (2018, September 28)

Introduction: Point-of-care blood gas test results may help to take therapeutic decision by their immediate impact on patient care. Recently, a novel cartridge-type blood gas analyzer, the GEM Premier ... [more ▼]

Introduction: Point-of-care blood gas test results may help to take therapeutic decision by their immediate impact on patient care. Recently, a novel cartridge-type blood gas analyzer, the GEM Premier 5000 (IL-Werfen) was commercialized and 24 analyzers were installed at the University Hospital of Liège. One of them was installed in the main central laboratory, the 23 other ones were installed into 19 patient care units. Before the implementation, we evaluated the analytical performance of all the 24 GEM Premier 5000, for the determination of whole blood pH, pCO2 and pO2, electrolytes (Na+, K+, Cl−), ionized calcium (iCa2+), glucose, lactate and co-oximetry parameters ((total hemoglobin (tHb), oxyhemoglobin (O2Hb), carboxyhemoglobin (COHb), methemoglobin (metHb), deoxyhemoglobin (HHb)). Method: First, we evaluated the performance of the GEM Premier 5000 dedicated to the central lab, so-called “referent analyzer”, with 3 levels of External Quality Controls material (EQC RNA Medicals). CLSI EP5 recommends 2 replicates per run, 1 or 2 runs per day, for a minimum of 20 days. Nevertheless, we analyzed the 3 levels of EQC, 2 replicates per run, 2 runs per day during 5 consecutive days. Afterwards, on the whole 24 GEM Premier 5000, we analyzed aqueous QC material (Werfen GEM System Evaluator, level 1-2), 3 replicates within a single run, once per day, during 5 consecutive days. We determined the manufacturer's claim for Within-Run and Total precisions for each. Co-oxymetry parameters were not evaluated on 4 analyzers. Then, we compared the all 23 analyzers to the “referent analyzer” of the central lab. Therefore, for each parameter, we showed in a Youden diagram all the results obtained by 23 analyzers. The position of the acceptance ranges were shown graphically using the specifications for Acceptable(%) Root Mean Standard Deviation (RMSD) proposed by the German Guidelines for Quality (RILIBAK) for whole blood parameter, for different ranges of parameters. Results: The results showed a good correlation between analyzers excepted for some parameters. Lactate and MetHb: level 2 were often over-estimated when compared to “Reference Analyzer”. It could be explained by the fact that this IQC level contains very low Lactate and MetHb rates. The pO2 level2: some results were over estimated (random errors >< cassette reagents >< low values). The pO2 level1: over-estimated with 8 analyzers letting us think that the cassette reagent of our “Reference Analyzer” had a bias in the lower range. Conclusion: Performance evaluation of a large cluster of Blood Gas Analyzers is always a challenge for a Hospital. Accreditation is one of the main goal in each Belgian laboratory. Hospital Accreditation is also discussed in Belgium. This study shows an interesting approach to validate Blood Gas Analyzers for highlighting data. Based on our study results, we estimated that the evaluated instrument are a suitable blood gas analyzer for both POCT and laboratory use. [less ▲]

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See detailRaman Chemical Imaging, a new tool in kidney stone structure analysis: Case-study and comparison to Fourier Transform Infrared spectroscopy
Castiglione, Vincent ULiege; Sacre, Pierre-Yves ULiege; CAVALIER, Etienne ULiege et al

in PLoS ONE (2018), 13(8), 0201460

Background and objectives: The kidney stone’s structure might provide clinical information in addition to the stone composition. The Raman chemical imaging is a technology used for the production of two ... [more ▼]

Background and objectives: The kidney stone’s structure might provide clinical information in addition to the stone composition. The Raman chemical imaging is a technology used for the production of two-dimension maps of the constituents' distribution in samples. We aimed at determining the use of Raman chemical imaging in urinary stone analysis. Material and methods: Fourteen calculi were analyzed by Raman chemical imaging using a confocal Raman microspectrophotometer. They were selected according to their heterogeneous composition and morphology. Raman chemical imaging was performed on the whole section of stones. Once acquired, the data were baseline corrected and analyzed by MCR-ALS. Results were then compared to the spectra obtained by Fourier Transform Infrared spectroscopy. Results: Raman chemical imaging succeeded in identifying almost all the chemical components of each sample, including monohydrate and dihydrate calcium oxalate, anhydrous and dihydrate uric acid, apatite, struvite, brushite, and rare chemicals like whitlockite, ammonium urate and drugs. However, proteins couldn't be detected because of the huge autofluorescence background and the small concentration of these poor Raman scatterers. Carbapatite and calcium oxalate were correctly detected even when they represented less than 5 percent of the whole stones. Moreover, Raman chemical imaging provided the distribution of components within the stones: nuclei were accurately identified, as well as thin layers of other components. Conversion of dihydrate to monohydrate calcium oxalate was correctly observed in the centre of one sample. The calcium oxalate monohydrate had different Raman spectra according to its localization. Conclusion: Raman chemical imaging showed a good accuracy in comparison with infrared spectroscopy in identifying components of kidney stones. This analysis was also useful in determining the organization of components within stones, which help locating constituents in low quantity, such as nuclei. However, this analysis is time-consuming, making it more suitable for research studies rather than routine analysis. [less ▲]

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See detailCase report: Uncommon Sulfamethoxazole Crystalluria
Castiglione, Vincent ULiege; CAVALIER, Etienne ULiege; GADISSEUR, Romy ULiege

in Clinical Biochemistry (2018)

We report seven Caucasian patients with unusual Sulfamethoxazole crystalluria on random urine sediment analysis. Crystals had very uncommon and various shapes and were identified thanks to infrared ... [more ▼]

We report seven Caucasian patients with unusual Sulfamethoxazole crystalluria on random urine sediment analysis. Crystals had very uncommon and various shapes and were identified thanks to infrared spectroscopy. An eGFR (MDRD) decrease was associated to crystalluria onset in three patients. [less ▲]

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