Publications of Géraldine BLAISE
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See detailLe pseudoxanthome élatique au-delà de la peau, de l'oeil et des vaisseaux.
Blaise, Géraldine ULiege; Franchimont, Claudine ULiege; Pierard, Gérald ULiege

in Revue Médicale de Liège (2009), 64

The main clinical manifestations of pseudoxanthoma elasticum (PXE) alter small arteries, the eyes and the skin. At the microanatomical level, the feature in common is an alteration of the elastic fibres ... [more ▼]

The main clinical manifestations of pseudoxanthoma elasticum (PXE) alter small arteries, the eyes and the skin. At the microanatomical level, the feature in common is an alteration of the elastic fibres that appear dystrophic and in part calcified. The disease is genetically transmitted as an autosomal recessive trait. The gene coding for the MRP6 protein is often mutated. Thus PXE appears as a metabolic disease conveyed by serum. [less ▲]

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See detailChildhood cutaneous leiomyosarcoma.
Blaise, Géraldine ULiege; Nikkels, Arjen ULiege; Quatresooz, Pascale ULiege et al

in Pediatric Dermatology (2009), 26(4), 477-9

Cutaneous leiomyosarcoma is a soft tissue neoplasm exhibiting an aggressive local behavior and a potential for distant metastases. It is rare during childhood and diagnosis can be challenging both ... [more ▼]

Cutaneous leiomyosarcoma is a soft tissue neoplasm exhibiting an aggressive local behavior and a potential for distant metastases. It is rare during childhood and diagnosis can be challenging both clinically and histologically. Surgical excision with wide lateral and deep margins is the treatment of choice, whereas radiotherapy and chemotherapy are contraindicated. Long-term follow-up is necessary as recurrences are not infrequent. [less ▲]

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See detailAcne iatrogene paroxystique et les inhibiteurs du recepteur du facteur de croissance epidermique (EGFR).
Pierard, Claudine ULiege; Blaise, Géraldine ULiege; Paquet, Philippe ULiege et al

in Revue Médicale de Liège (2007), 62(1), 11-4

Paroxysmal drug-induced acne is a peculiar condition recognized for decades in dermatology. It can be induced by a variety of drugs. In recent years, the epidermal growth factor receptor inhibitors used ... [more ▼]

Paroxysmal drug-induced acne is a peculiar condition recognized for decades in dermatology. It can be induced by a variety of drugs. In recent years, the epidermal growth factor receptor inhibitors used in oncology have shown this type of adverse effects. The pathogenic mechanism is likely related to the EGF implication in the rupture of the microcomedo wall resulting in the perifollicular inflammatory reaction typical for acne. Other cutaneous adverse effects have been reported with anti-EGFR drugs including paronychia and xerosis. The dermatological treatments of these drug-induced disorders must be adequately targeted. [less ▲]

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