Publications of Sophie ALLEPAERTS
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See detailApproche critique du traitement prolonge par inhibiteurs de la pompe a protons chez les personnes agees.
DELHOUGNE, Nicolas ULiege; Allepaerts, Sophie ULiege; GAST, Pierrette ULiege et al

in Revue medicale de Liege (2020), 75(1), 10-16

Proton pump inhibitors (PPI) are drugs frequently used for gastric acid-induced conditions. Their use is constantly increasing and due to the apparent absence of side-effects, the treatment is not ... [more ▼]

Proton pump inhibitors (PPI) are drugs frequently used for gastric acid-induced conditions. Their use is constantly increasing and due to the apparent absence of side-effects, the treatment is not reassessed, even for the elderly. However, there are many cases of misprescribing while concerns about some side-effects are rising. Old people are weakened by their particular homeostasis and their associated medical conditions. Therefore, it seems useful to particularly insist on side-effects of the PPI, their indications and the ways of withdrawal, first of all for the elderly. [less ▲]

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See detailClinical impact of nutritional status and energy balance in elderly hospitalized patients
ALLEPAERTS, Sophie ULiege; Buckinx, Fanny ULiege; Bruyère, Olivier ULiege et al

in Journal of Nutrition, Health and Aging (2020), 24(10), 1073-79

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See detailAssessment of the energy expenditure of Belgian nursing home residents using indirect calorimetry
Buckinx, Fanny ULiege; Paquot, Nicolas ULiege; FADEUR, Marjorie ULiege et al

in Nutrition (2019), 57

Objectives: The aim of this study was to assess the energy expenditure of Belgian nursing home residents using indirect calorimetry and compare the energy expenditure with energy intake. Methods: Indirect ... [more ▼]

Objectives: The aim of this study was to assess the energy expenditure of Belgian nursing home residents using indirect calorimetry and compare the energy expenditure with energy intake. Methods: Indirect calorimetry was performed in nursing home residents to estimate their basal metabolism. The basal metabolism was multiplied by a physical activity level coefficient and energy expenditure that was related to thermogenesis (i.e., 10% of the total amount of energy ingested over 24 h) was added. In this way, we obtained the total energy expenditure of each nursing home resident. The nutritional intake of each resident was calculated using the precise food-weighing method over a 3-d period. The difference between energy expenditure and consumption was calculated for each patient and the mean of the difference in the population was calculated. These quantitative variables were compared by means of analysis of variance. Results: A total of 25 subjects were included in this study (88.1 ± 5.8 y; 84% women). The estimated mean basal metabolism was 1087.2 ± 163.2 kcal. The physical activity level was 1.29 ± 0.1 on average and the energy expenditure due to thermogenesis was 163.1 ± 28.9 kcal. Thus, the mean daily energy expenditure was 1575.2 ± 210.6 kcal, which was within the range of the actual calculated energy intake of the residents (1631.5 ± 289.3 kcal; P = 0.33). Conclusions: The estimated energy intake of Belgian nursing home residents seems appropriate for their energy expenditure. © 2018 Elsevier Ltd [less ▲]

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See detailSerum albumin level and long-term outcome in acute heart failure
ANCION, Arnaud ULiege; Allepaerts, Sophie ULiege; Robinet, Sébastien ULiege et al

in Acta Cardiologica (2018)

Objective: Hypoalbuminemia is common in heart failure (HF), especially in elderly patients. It is associated with an increased risk of death. The present study sought to examine the prognostic ... [more ▼]

Objective: Hypoalbuminemia is common in heart failure (HF), especially in elderly patients. It is associated with an increased risk of death. The present study sought to examine the prognostic significance of serum albumin level in the prediction of long-term mortality in patients admitted for acute HF. Methods and results: We examined the association between albumin and hospital mortality in a cohort of 509 patients admitted for acute HF. None of the patients had infectious disease, severe arrhythmias (atrial fibrillation, ventricular tachycardia, ventricular fibrillation), required invasive ventilation or presented with acute coronary syndrome or primary valvular disease. Sixty-nine patients (14%) died during the 1-year follow-up. With multivariable analysis, haemoglobin level (p =.003), systolic blood pressure (p =.004) and serum albumin level (p =.003) emerged as independent predictors of long-term mortality. Hypoalbuminemia (<35.7 g/L) had a hazard ratio of 2.01 (95% CI 1.24–3.25) and haemoglobin of 2.6 (95% CI 1.29–5.22) for predicting long-term mortality. Conclusions: Serum albumin level measured at admission, especially if combined with anaemia, can serve as a simple prognostic factor in acute HF for predicting long-term outcome. © 2019, © 2019 Belgian Society of Cardiology. [less ▲]

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See detailThe authors reply: Letter on: "Pitfalls in the measurement of muscle mass: a need for a reference standard" by Clark et al.
Buckinx, Fanny ULiege; Landi, Francesco; Cesari, Matteo et al

in Journal of Cachexia, Sarcopenia and Muscle (2018), 9(7), 1272-1274

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See detailThe authors reply: Dual energy X-ray absorptiometry: gold standard for muscle mass ? by Scafoglieri et al.
Buckinx, Fanny ULiege; Landi, F.; Cesari, M. et al

in Journal of Cachexia, Sarcopenia and Muscle (2018), 9

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See detailPitfalls in the measurement of muscle mass; a need for a reference standard.
Buckinx, Fanny ULiege; Landi, Francesco; Cesari, francesco et al

in Journal of Cachexia, Sarcopenia and Muscle (2018), 9

Background: All proposed definitions of sarcopenia include the measurement of muscle mass, but the techniques and threshold values used vary. Indeed, the literature does not establish consensus on the ... [more ▼]

Background: All proposed definitions of sarcopenia include the measurement of muscle mass, but the techniques and threshold values used vary. Indeed, the literature does not establish consensus on the best technique for measuring lean body mass. Thus, the objective measurement of sarcopenia is hampered by limitations intrinsic to assessment tools. The aim of this study was to review the methods to assess muscle mass and to reach consensus on the development of a reference standard. Methods: Literature reviews were performed by members of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis working group on frailty and sarcopenia. Face-to-face meetings were organized for the whole group to make amendments and discuss further recommendations. Results: A wide range of techniques can be used to assess muscle mass. Cost, availability, and ease of use can determine whether the techniques are better suited to clinical practice or are more useful for research. No one technique subserves all requirements but dual energy X-ray absorptiometry could be considered as a reference standard (but not a gold standard) for measuring muscle lean body mass. Conclusions: Based on the feasibility, accuracy, safety, and low cost, dual energy X-ray absorptiometry can be considered as the reference standard for measuring muscle mass. [less ▲]

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See detailSerum albumin level and hospital mortality in acute non-ischemic heart failure.
ANCION, Arnaud ULiege; Allepaerts, Sophie ULiege; Oury, Cécile ULiege et al

in ESC Heart Failure (2017), 4(2), 138-145

AIMS: Hypoalbuminemia is common in heart failure (HF), especially in elderly patients. It is associated with an increased risk of death. The present study sought to examine the prognostic significance of ... [more ▼]

AIMS: Hypoalbuminemia is common in heart failure (HF), especially in elderly patients. It is associated with an increased risk of death. The present study sought to examine the prognostic significance of serum albumin level in the prediction of hospital mortality in patients admitted for acute non-ischemic HF. METHODS AND RESULTS: We examined the association between albumin and hospital mortality in a cohort of 546 patients admitted for acute non-ischemic HF. None of the patients had infectious disease, severe arrhythmias (atrial fibrillation, ventricular tachycardia, ventricular fibrillation), required invasive ventilation, or presented with acute coronary syndrome or primary valvular disease. Thirty-six patients (7%) died during the hospital stay. These patients were significantly older (78 +/- 9 vs. 72 +/- 12 years; P = 0.006), had higher heart rate (P < 0.0001), increased creatinine level (P = 0.01), lower systolic and diastolic blood pressures (P < 0.05), elevated leucocyte count (P = 0.001), and lower albumin levels (31.3 +/- 5.6 g/L vs. 36.9 +/- 4.1 g/L; P < 0.001). With multivariable analysis, age (P = 0.01), heart rate (P < 0.0003), diastolic blood pressure (P < 0.01), leukocyte count (P = 0.009), and serum albumin level (P < 0.0001) emerged as independent predictors of hospital mortality. Hypoalbuminemia (<34 g/L) yielded the best sensitivity (78.8%) and specificity (75%) for predicting hospital death. CONCLUSIONS: Serum albumin level measured at admission can serve as a simple prognostic factor in acute non-ischemic HF. Hypoalbuminemia is associated with increased risk of hospital mortality, especially in elderly patients. [less ▲]

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See detailEnergy and nutrient content of food served and consumed by nursing home residents
Buckinx, Fanny ULiege; ALLEPAERTS, Sophie ULiege; PAQUOT, Nicolas ULiege et al

in Journal of Nutrition, Health and Aging (2017), 21(6), 727-32

Objective: The aim of this study was to compare energy and protein content of the served food with the actual intake from the food consumed by nursing home residents. This study also aimed to compare food ... [more ▼]

Objective: The aim of this study was to compare energy and protein content of the served food with the actual intake from the food consumed by nursing home residents. This study also aimed to compare food intake and dietary allowances. Design: This is a cross sectional study. Setting: This study was performed in nursing homes. Participants: Residents of these 2 nursing homes were eligible for the study if they agreed to participate and if they meet the selection criteria (to be older than 65 years and have a regular texture diet). Measurement: Nutrient content of the served food and real food consumption was calculated for all meals during a 5-day period by precise weighting method. Difference between consumed and served dietary content was evaluated by the Chi² test. Results: Seventy-four Belgian nursing home residents (75% of women, 85.8 ± 7.04 years on average) were included in this study. These subjects had a mean body mass index of 24.9 ± 4.83 kg/m². The mean energy content of the served food was 1783.3 ± 125.7 kcal per day. However, residents did not eat the whole of the meals and the actual energy content of the consumed food was significantly less (1552.4 ± 342.1 kcal per day; p<.001). The average protein content of the food served was equal to 0.96 ± 0.20 g/kg/day and the average consumption of protein by the residents was 0.88 ± 0.25 g/kg/day. The difference between protein served and consumed was also significant (p=.04). Moreover, people considered as well nourished, eating significantly more energy than the others (p=.04). Conclusion: Meals served in nursing homes are not entirely consumed by their residents. As expected, the energy consumed are lower in subjects considered as malnourished or at risk of malnutrition. [less ▲]

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See detailComment je traite ....... Le delirium chez le patient âgé
CHRISTELBACH, Sophie ULiege; ALLEPAERTS, Sophie ULiege; PETERMANS, Jean ULiege

in Revue Médicale de Liège (2016)

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See detailEnergy and nutrient contents of food served and consumed by nursing home residents
Buckinx, Fanny ULiege; Paquot, Nicolas ULiege; Allepaerts, Sophie ULiege et al

in European Geriatric Medicine (2015, September), 6S1

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See detailTreatment of pneumonia in demented patients
ALLEPAERTS, Sophie ULiege; PETERMANS, Jean ULiege

Learning material (2015)

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See detailEnergy and nutrient contents of food served and consumed by nursing home residents
Buckinx, Fanny ULiege; PAQUOT, Nicolas ULiege; ALLEPAERTS, Sophie ULiege et al

in The Journal of Nursing Home Research Sciences (2015), 1

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