Publications of Jean-Evrard CABAY
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See detailTinnitus distress : a paradoxical attention to the sound?
MAUDOUX, Audrey ULiege; KANDEEPAN, Sivayini; Ribeiro de Paula, Demetrius et al

in Journal of Neurology (2019)

Tinnitus, the perception of sound in the absence of external stimuli, is often a disturbing symptom for which the underlying functional neuroanatomy still remains poorly understood. Most studies have ... [more ▼]

Tinnitus, the perception of sound in the absence of external stimuli, is often a disturbing symptom for which the underlying functional neuroanatomy still remains poorly understood. Most studies have focused solely on functional connectivity changes in the auditory cortex of tinnitus patients. The aim of this study was to investigate whether a correlation exists between tinnitus behavioural scores and functional brain connectivity of five resting-state networks comprising the auditory, the default mode, the external control left and right, and the salience network. For this purpose, a large sample of one hundred and thirty-five subjects underwent resting-state functional magnetic resonance imaging and their behavioural scores were obtained using clinical evaluations. Networks were extracted using independent component analysis, and functional connectivity patterns in the extracted networks were evaluated by a graph theoretical approach. The effects of tinnitus for each network were investigated by correlating the graph strength of all the regions with the tinnitus behavioural scores using stepwise fit regression analysis. Results indicated that alterations of functional interactions between key neural circuits of the brain are not limited to one single network. In particular, tinnitus distress showed a strong correlation with the connectivity pattern within and between the right executive control network and the other four resting-state networks, indicating that tinnitus distress is probably the consequence of a hyperactive attention condition. Among the behavioural scores, the strongest correlation was observed between age and hearing loss, while the tinnitus objective loudness was not correlated with any behavioural scores. [less ▲]

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See detailHearing tinnitus and reacting to tinnitus: two processes involving different networks
MAUDOUX, Audrey ULiege; DE RIDDER, D; VANHECKE, W et al

Conference (2016, March)

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See detailTinnitus and dysfunctional interactions between distributed resting state networks.
MAUDOUX, Audrey ULiege; VANNEST, S; DE RIDDER, D et al

Poster (2014, March)

Detailed reference viewed: 20 (1 ULiège)
See detailThe Neuroscience of tinntisu: insights from resting-state fMRI
MAUDOUX, Audrey ULiege; De RIDDER, D; VANHECKE, W et al

Conference (2013, March)

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See detailThe neuroscience of tinnitus: Perspectives from human neuroimaging studies
Maudoux, Audrey ULiege; Vanneste, Sven; De Ridder, Dirk et al

Conference (2012, November)

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See detailInvestigating the tinnitus brain using resting-state fMRI
Maudoux, Audrey ULiege; Vanneste, Sven; De Ridder, Dirk et al

Conference (2012, June)

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See detailAuditory Resting-State Network Connectivity in Tinnitus: a Functionnal MRI Study.
MAUDOUX, Audrey ULiege; LEFEBVRE, Philippe ULiege; CABAY, Jean-Evrard ULiege et al

in PLoS ONE (2012)

The underlying functional neuroanatomy of tinnitus remains poorly understood. Few studies have focused on functional cerebral connectivity changes in tinnitus patients. The aim of this study was to test ... [more ▼]

The underlying functional neuroanatomy of tinnitus remains poorly understood. Few studies have focused on functional cerebral connectivity changes in tinnitus patients. The aim of this study was to test if functional MRI ‘‘resting-state’’ connectivity patterns in auditory network differ between tinnitus patients and normal controls. Thirteen chronic tinnitus subjects and fifteen age-matched healthy controls were studied on a 3 tesla MRI. Connectivity was investigated using independent component analysis and an automated component selection approach taking into account the spatial and temporal properties of each component. Connectivity in extra-auditory regions such as brainstem, basal ganglia/NAc, cerebellum, parahippocampal, right prefrontal, parietal, and sensorimotor areas was found to be increased in tinnitus subjects. The right primary auditory cortex, left prefrontal, left fusiform gyrus, and bilateral occipital regions showed a decreased connectivity in tinnitus. These results show that there is a modification of cortical and subcortical functional connectivity in tinnitus encompassing attentional, mnemonic, and emotional networks. Our data corroborate the hypothesized implication of non-auditory regions in tinnitus physiopathology and suggest that various regions of the brain seem involved in the persistent awareness of the phenomenon as well as in the development of the associated distress. leading to disabling chronic tinnitus. [less ▲]

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See detailNodal staging of head and neck squamous cell carcinomas : impact of a dedicated PET/CT protocol.
MINON, AL.; CABAY, Jean-Evrard ULiege; DEMEZ, Pierre ULiege et al

in Journal of Nuclear Medicine (2012), 53(SUPPL), 1354

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See detailAuditory resting-state network connectivity in tinnitus: a functional MRI study.
MAUDOUX, Audrey ULiege; Lefèbvre, Philippe ULiege; CABAY, Jean-Evrard ULiege et al

in PLoS ONE (2012), 7(5), 36222

The underlying functional neuroanatomy of tinnitus remains poorly understood. Few studies have focused on functional cerebral connectivity changes in tinnitus patients. The aim of this study was to test ... [more ▼]

The underlying functional neuroanatomy of tinnitus remains poorly understood. Few studies have focused on functional cerebral connectivity changes in tinnitus patients. The aim of this study was to test if functional MRI "resting-state" connectivity patterns in auditory network differ between tinnitus patients and normal controls. Thirteen chronic tinnitus subjects and fifteen age-matched healthy controls were studied on a 3 tesla MRI. Connectivity was investigated using independent component analysis and an automated component selection approach taking into account the spatial and temporal properties of each component. Connectivity in extra-auditory regions such as brainstem, basal ganglia/NAc, cerebellum, parahippocampal, right prefrontal, parietal, and sensorimotor areas was found to be increased in tinnitus subjects. The right primary auditory cortex, left prefrontal, left fusiform gyrus, and bilateral occipital regions showed a decreased connectivity in tinnitus. These results show that there is a modification of cortical and subcortical functional connectivity in tinnitus encompassing attentional, mnemonic, and emotional networks. Our data corroborate the hypothesized implication of non-auditory regions in tinnitus physiopathology and suggest that various regions of the brain seem involved in the persistent awareness of the phenomenon as well as in the development of the associated distress leading to disabling chronic tinnitus. [less ▲]

Detailed reference viewed: 38 (3 ULiège)
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See detailResting-state activity in the tinnitus brain
Maudoux, Audrey ULiege; LEFEBVRE, Philippe ULiege; CABAY, Jean-Evrard ULiege et al

Conference (2011, March)

Detailed reference viewed: 19 (3 ULiège)
See detailResting-state auditory network in tinnitus: a fMRI study
Maudoux, Audrey ULiege; LEFEBVRE, Philippe ULiege; CABAY, Jean-Evrard ULiege et al

Poster (2010, June)

Detailed reference viewed: 23 (2 ULiège)
See detailResting-state auditory network in tinnitus: a fMRI study
Maudoux, Audrey ULiege; LEFEBVRE, Philippe ULiege; CABAY, Jean-Evrard ULiege et al

Conference (2010, June)

Detailed reference viewed: 13 (1 ULiège)
See detailResting-state auditory network in tinnitus: a fMRI study
Maudoux, Audrey ULiege; LEFEBVRE, Philippe ULiege; CABAY, Jean-Evrard ULiege et al

Conference (2010, March)

Detailed reference viewed: 28 (2 ULiège)
See detailPET/CT imaging of skull base meningiomas using 1-18F-fluoro-L-tyrosine; initial report.
RUTTEN, I.; CABAY, Jean-Evrard ULiege; WITHOFS, Nadia ULiege et al

in PROCEEDINGS OF XIIIth SYMPOSIUM OF THE BELGIAN SOCIETY OF NUCLEAR MEDICINE (2007, May)

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See detailPET/CT of skull base meningiomas using 2-F-18-fluoro-L-tyrosine: Initial report
Rutten, Isabelle; Cabay, Jean-Evrard ULiege; Withofs, Nadia ULiege et al

in Journal of Nuclear Medicine (2007), 48(5), 720-725

Precise delineation of the shape of skull base meningiomas is critical for their treatment and follow-up but is often difficult using conventional imaging such as CT and MRI. We report our results with ... [more ▼]

Precise delineation of the shape of skull base meningiomas is critical for their treatment and follow-up but is often difficult using conventional imaging such as CT and MRI. We report our results with PET/CT and 2-(18)F-fluoro-L-tyrosine ((18)F-TYR), a marker of amino acid transport, as part of the yearly follow-up of irradiated patients. METHODS: Eleven patients (mean age, 56.5 y) with skull base meningiomas (n=13 lesions) previously irradiated were included. All patients received 300 MBq of (18)F-TYR and were imaged after 30 min of uptake, using a dedicated PET/CT system. The images were first visually examined, and regions of interest (ROI) were then placed over the transaxial PET slice showing the highest uptake. Another ROI was placed over the normal parietal cortex. Tumor-to-cortex activity ratios were obtained by dividing the maximum pixel value in the tumor ROI by the maximum pixel value in the cortex ROI. The PET/CT images were compared with the MR images obtained as part of routine follow-up. RESULTS: Accumulation of the tracer was higher in all meningiomas than in the surrounding tissue. The tumor-to-cortex activity ratio was 2.53 +/- 0.35 (range, 1.3-6). Nonneoplastic tissue such as hyperemic cavernous sinus did not take up the radionuclide and was therefore easily distinguished from the meningioma. The (18)F-TYR anomalies completely overlapped with the MR image in 54% of the tumors, extended beyond the MRI lesion in 38% of the tumors, and were smaller in 8% of the tumors. CONCLUSION: Meningiomas of the skull base are clearly visualized using (18)F-TYR PET/CT, even after irradiation. In addition to MRI, (18)F-TYR PET/CT images may contribute to the evaluation, delineation, and follow-up of these tumors. [less ▲]

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See detailPET/CT imaging of skull base meningiomas using 2-18F-fluoro-L-tyrosine : Initial report.
Rutten, Isabelle; Cabay, Jean-Evrard ULiege; Withofs, Nadia ULiege et al

in Journal of Nuclear Medicine (2007), 48(SUPPL), 11

Detailed reference viewed: 17 (5 ULiège)
See detailRadiographic, computed tomographic, magnetic resonance and rhinoscopic findings in dogs with nasal aspergillosis
Saunders, J.; Clercx, Cécile ULiege; CABAY, Jean-Evrard ULiege et al

in Annual Meeting of ACVR - Chicago, Illinois - USA - Décembre 2002 (2002, December)

Detailed reference viewed: 11 (0 ULiège)