Publications of Jorge ARRESE ESTRADA
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See detailGranulomatous reactions from tattoos following BRAF inhibitor therapy
GIET, Gabrielle ULiege; LEBAS, Eve ULiege; RORIVE, Andrée ULiege et al

in Case Reports in Dermatology (2019), 11

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See detailPachyderma in primary cutaneous NK and T-cell lymphoma and leukemia cutis
LEBAS, Eve ULiege; CHIAN, Cesar; TASSOUDJI, Nazli ULiege et al

in Case Reports in Dermatology (2017), 9(3), 151-157

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See detailEpidemiological aspects and genotypic characterization of T.violaceum strains collected during a Belgian National survey on anthropophilic tinea
SACHELI, Rosalie ULiege; Dekkers, Charlotte; GRAIDE, Hélène ULiege et al

in Mycoses (2015, October), 58(Supplement 4), 189

Objectives The last two years, clinical cases of tinea capitis caused by Trichophyton violaceum (T. violaceum), have been identified in Belgium. To better understand the emergence of this species in the ... [more ▼]

Objectives The last two years, clinical cases of tinea capitis caused by Trichophyton violaceum (T. violaceum), have been identified in Belgium. To better understand the emergence of this species in the population, the Belgian National Reference Center (NRC Liège) launched a one-year national survey in 2013. Epidemiological aspects and genotypic characterization of the strains were included. Methods The study was conducted from March 2013 up to February 2014. All Belgian laboratories were asked to send M. audouinii and T. violaceum strains isolated from hair to the NRC with a form to fill in including epidemiological data. The fungal strains were identified by microscopy or ITS sequencing in case of doubtful identification. The genotypic analysis was performed by the DiversiLab® system (bioMérieux) for DNA fingerprinting and analysis. Epidemiological data were analyzed with the help of a biostatistician. Results Amongst the collected isolates, 23 strains were confirmed as T.violaceum (results concerning the 116 M. audouinii strains have already been reported). Analysis of the epidemiological characteristics of the infected population shows that the main age category concerns 0-4 year-old children (n=9, 39,1%) with a sex-ratio M/F of 1.875. Data concerning the geographic origin of the family were present in 82,6% of the cases and reveal that patients were mainly of Ethiopian origin (n=8, 57,9% of known cases). One patient was also from Burundi showing that T. violaceum strains probably circulate mainly in East Africa. The genotypic analysis led to the distinction of 2 variants of T. violaceum. The major group was composed of 17 strains which were mainly collected in the North of Belgium and included also the reference strain (18/23, 83,3%). The other group (6 strains) was close to the major group but the analysis of the spectral superposition showed some differences between these two groups, defining two distinct variants of T. violaceum in the Belgian population. This second variant was mainly recovered from South Belgium (5/6, 83,3%). No correlation could be made between the genotypic group and a particular ethnical origin as Ethiopian subjects were found in both groups. Conclusion The DiversiLab® system proved to be an efficient method to investigate the molecular epidemiology of dermatophytes infections as reported previously for M. audouinii. These results show that two distinct isolates co-exist in Belgium providing evidence of genetic heterogeneity and a possible spread of one genotypic variant in a restricted geographic area or the co-existence of two variants circulating in different African communities. However, no clear correlation could be established between the appartenance to a group and epidemiological factors, such as age or ethnical origin. [less ▲]

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See detailEpidemiological aspects and genotypic characterization of strains of Microsporum audouinii isolated in the context of a Belgian National survey on anthropophilic tinea
SACHELI, Rosalie ULiege; Dekkers, Charlotte; DARFOUF, Rajae ULiege et al

Poster (2015, May)

Objectives The last two years, clinical cases of tinea capitis caused by Microsporum audouinii (M. audouinii), have increased in Belgium. To better understand the emergence of this species in the ... [more ▼]

Objectives The last two years, clinical cases of tinea capitis caused by Microsporum audouinii (M. audouinii), have increased in Belgium. To better understand the emergence of this species in the population, the Belgian National Reference Center (NRC) for dermatophytes launched a national survey in 2013. Epidemiological aspects and genotypic characterization of the strains were included. Methods The study was conducted from March 2013 up to February 2014. All Belgian laboratories were asked to send M. audouinii strains isolated from hair to the NRC with a form to fill in including epidemiological informations. The fungal strains were identified by microscopy or ITS sequencing in case of doubt. The genotypic analysis was performed by the DiversiLab® system (bioMérieux) for DNA fingerprinting and analysis. Epidemiological informations were analyzed with the help of a biostatistician. Results Among the collected isolates, 117 strains have been currently confirmed as M. audouinii. Analysis of the epidemiological characteristics of the infected population shows that the main age category concerns 5-9 year-old children (64%, p< 0,0001) with a sex-ratio M/F of 1.97. Data concerning the geographic origin of the family have been obtained in only 33,6% of the cases. It reveals that strains have been mainly isolated from patients with a Belgian nationality (43,6%) suggesting bias in the data collection. The geographic origin of the remaining group includes several African countries such as Congo (20,61%), Guinea (12,8%) and Burundi (5,12%). The genotypic analysis led to the distinction of 6 genotypic variants of M. audouinii. One of these variants was exclusively recovered from South Belgium (11 strains). The major group was composed of 96 strains, well distributed in different Belgium locations. Two other groups of three strains each were close to the major group but the analysis of the spectral superposition showed some differences between these groups. The two last groups were clearly different from the major group but species identification was confirmed by ITS sequencing. Conclusion The results of the genomic analysis by Diversilab, show that several groups of M. audouinii isolates co-exist in Belgium providing evidence of genetic heterogeneity. However, no clear correlation could be established between the appartenance to a group and epidemiological factors, such as the age or ethnical origin. ________________________________________ [less ▲]

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See detailMyxofibrosarcoma
CASTRONOVO, Charlotte ULiege; ARRESE ESTRADA, Jorge ULiege; QUATRESOOZ, Pascale ULiege et al

in Rare Tumors (2013), 5(15), 60-61

Myxofibrosarcoma (MFS) is a variant of the group of malignant fibrous histiocytomas. It is one of the most aggressive types of soft tissue neoplasms. The clinical presentation is not pathognomonic and the ... [more ▼]

Myxofibrosarcoma (MFS) is a variant of the group of malignant fibrous histiocytomas. It is one of the most aggressive types of soft tissue neoplasms. The clinical presentation is not pathognomonic and the histological aspects are highly heterogenous, frequently delaying the diagnosis or leading to misdiagnosis. Complementary histochemical and immunohistochemical stainings are mandatory to achieve the diagnosis of MFS. A 78-year-old male patient is presented illustrating this diagnostic pitfall. Extensive surgery followed by radiotherapy is the first choice treatment. [less ▲]

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See detailChronic annular lesions of the cheeks
LOTHER, Anne Sophia; ARRESE ESTRADA, Jorge ULiege; NIKKELS, Arjen ULiege

in International Journal of Dermatology (2013), (52), 649-650

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See detailChronic annular lesions of the cheeks
LOTHER, Anne-Sophia; ARRESE ESTRADA, Jorge ULiege; NIKKELS, Arjen ULiege

in International Journal of Dermatology (2012)

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See detailLe cas clinique du mois. Carcinome basocellulaire pédicule et pigmenté: une présentation inhabituelle.
Azzam, C.; Arrese Estrada, Jorge ULiege; Jacquemin, Denise ULiege et al

in Revue Médicale de Liège (2006), 61(9), 614-6

Basal cell carcinomas (BCC) are the most common malignant neoplasms in humans. Clinical misdiagnoses are not uncommon. These cancers are classified according to their histological and clinical ... [more ▼]

Basal cell carcinomas (BCC) are the most common malignant neoplasms in humans. Clinical misdiagnoses are not uncommon. These cancers are classified according to their histological and clinical characteristics which exhibit distinct malignant behaviours. It is important to be aware of the different clinical presentations both for the accurate diagnosis and tumour management. We report the case of a 78-year-old man, who presented an unusual pedunculated and pigmented BCC. This combined aspect is rarely encountered. [less ▲]

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See detailLa peau et le temps de la menopause.
Thirion, Laurence; Franchimont, Claudine ULiege; Arrese Estrada, Jorge ULiege et al

in Revue Médicale de Liège (2006), 61(3), 159-62

The estrogen deficit occurring at menopause manifests itself under various modalities in the diverse organs and their functions. Skin does not escape this global involutive process. In addition to the ... [more ▼]

The estrogen deficit occurring at menopause manifests itself under various modalities in the diverse organs and their functions. Skin does not escape this global involutive process. In addition to the effects of chronological ageing, sunlight exposure and other environmental and endogenous stimuli, the climacteric appears to exert some dramatic consequences on skin biology and aspect. The epidermis, its adnexae and the dermis are altered by this process. The epidermis may become xerotic and exhibits altered functions. The dermis thins out and its elasticity decreases in concert with the decline in bone mass. The skin microcirculation is impaired. These aspects are some of the better-worked out skin climacteric changes of which in turn seem to be stabilized or in part reversible with hormone replacement therapy (HRT). [less ▲]

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See detailHic et Nunc. Naevus ou melanome?
Pierard, Claudine ULiege; Pierard, Gérald ULiege; Quatresooz, Pascale ULiege et al

in Revue Médicale de Liège (2006), 61(1), 43-7

In Wallonia, the incidence of cutaneous melanoma has steadily increased over the past decades. Hopefully, the early diagnosis made at the premetastatic stage has benefited from great advances both in the ... [more ▼]

In Wallonia, the incidence of cutaneous melanoma has steadily increased over the past decades. Hopefully, the early diagnosis made at the premetastatic stage has benefited from great advances both in the clinical and laboratory fields. Thanks to the "Groupement Oncologique Universitaire Wallonie-Liege" (GOUWL) organization, some efforts are currently made in order to better frame and normalize the management of cancer patients. Some medical staffs involved in prospective clinical research bring by their own experience further practical insights for the benefit to the patients. In this field, Belgium is not destituted. We report a brief review of the contribution of the Mosan Study Group of Pigmentary Tumors (GMETP) at the University Hospital of Liege. [less ▲]

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See detailGenophotodermatoses.
Arrese Estrada, Jorge ULiege; Henry, Frédérique ULiege; Pierard, Gérald ULiege

in Revue Médicale de Liège (2005), 60 Suppl 1

Genophotodermatoses can result from a defect in melanin synthesis, a defect in DNA repair or a congenital photosensibility.

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See detailUn nuevo enfoque sobre la epidemioloiga de las onicomicosis.
Arrese Estrada, Jorge ULiege; Valverde, J.; Pierard, Gérald ULiege

in Revista Iberoamericana de Micología (2005), 22

Onychomycoses represent a group of nail affections caused by one or more fungi. Whether aging represents a risk factor for developing onychomycosis, remains a question. In the present work, we studied the ... [more ▼]

Onychomycoses represent a group of nail affections caused by one or more fungi. Whether aging represents a risk factor for developing onychomycosis, remains a question. In the present work, we studied the variations in frequency and prevalence of onychomycoses and non-mycotic onychodystrophies according to age. Our results show that there is an increase in the frequency and prevalence of onychomycoses and non-mycotic onychodystrophies predominantly in patients over forty years of age. [less ▲]

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See detailItraconazole corneofungimetry bioassay on Malassezia species.
Pierard, Gérald ULiege; Arrese Estrada, Jorge ULiege; Pierard, Claudine ULiege

in Mycoses (2004), 47(9-10), 418-21

Yeasts of the genus Malassezia are part of the normal skin biocenosis and are involved in a series of distinct skin disorders and specific dermatomycoses in man and animals. Several species are currently ... [more ▼]

Yeasts of the genus Malassezia are part of the normal skin biocenosis and are involved in a series of distinct skin disorders and specific dermatomycoses in man and animals. Several species are currently distinguished. Their relative in vitro susceptibility to antifungals appears different according to the species and to the nature and route of administration of the drug. Corneofungimetry is an ex vivo bioassay allowing to test the fungal response on human stratum corneum following oral intake of a given antifungal by volunteers. Two series of cyanoacrylate skin surface strippings (CSSS) were harvested from the volar forearm of 30 volunteers before and after a 2-week treatment with itraconazole 200 mg daily. They were coated by olive oil and inoculated with suspensions of seven different Malassezia spp. After a 1-week culture on CSSS, the amount of viable yeasts was assessed using neutral red staining assisted by computerized image analysis. Growth of the seven species was not similar on the CSSS from untreated stratum corneum. The ranking order from the most proliferative to the least was M. restricta, M. sympodialis, M. globosa, M. furfur, M. obtusa, M. slooffiae and M. pachydermatis. Their growth was abated to almost the same level after itraconazole treatment. It is concluded that in vivo treatment with itraconazole is highly active against all Malassezia spp. colonizing the human stratum corneum. [less ▲]

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See detailLe cas clinique du mois. La syphilis, une MST de retour en nos murs.
Flagothier, Caroline ULiege; Arrese Estrada, Jorge ULiege; Pierard, Claudine ULiege et al

in Revue Médicale de Liège (2004), 59(7-8), 426-9

Sexually transmitted diseases (STD) show frequent epidemiological changes. We report a case of secondary syphilis diagnosed in a 32-year old woman during post-partum. The disease, although showing a ... [more ▼]

Sexually transmitted diseases (STD) show frequent epidemiological changes. We report a case of secondary syphilis diagnosed in a 32-year old woman during post-partum. The disease, although showing a typical presentation, raises the problem of dating with precision the contamination time. This is of importance for treating the newborn at risk of congenital syphilis. We highlight the constant attention that should be brought to disclose this venereal disease that shows so variable clinical and histological presentations. Syphilis seems on the rise in the Mosan valley and in some cities where prostitution is imported from Eastern Europe and Africa. [less ▲]

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See detailLe cas clinique du mois. Fasciolase cutanée.
Garcia Moreno Rodriguez, Renata ULiege; Arrese Estrada, Jorge ULiege; Ugarte, G. et al

in Revue Médicale de Liège (2004), 59(10), 552-4

Fascioliasis is an hepato-biliary distomatosis which may exceptionally manifest itself in the skin. We report a case presenting as nodules localized on the trunk. Lesions cleared under praziquantel ... [more ▼]

Fascioliasis is an hepato-biliary distomatosis which may exceptionally manifest itself in the skin. We report a case presenting as nodules localized on the trunk. Lesions cleared under praziquantel treatment. [less ▲]

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See detailLe carcinome de Merkel.
Barile, Paola ULiege; Leroy, Cécile ULiege; Bolle, S. et al

in Journal Français d'Ophtalmologie (2004), 27(4), 432-6

Merkel cell carcinoma is a neuroendocrine tumor of the skin, originating from neuroendocrine cells. A case report of Merkel cell carcinoma, discovered in a 77-Year-old woman, was diagnosed and confirmed ... [more ▼]

Merkel cell carcinoma is a neuroendocrine tumor of the skin, originating from neuroendocrine cells. A case report of Merkel cell carcinoma, discovered in a 77-Year-old woman, was diagnosed and confirmed on a biopsy. Diagnostic and therapeutic orientations of this unusual but malignant tumor are described. [less ▲]

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See detailComment je traite ... une dermatite seborrhéique.
Pierard, Claudine ULiege; Arrese Estrada, Jorge ULiege; Pierard, Gérald ULiege

in Revue Médicale de Liège (2003), 58(2), 67-9

Seborrhoeic dermatitis results from a peculiar inflammatory reaction directed to yeasts of the genus Malassezia which are present at the skin surface. The current therapeutic strategies to control ... [more ▼]

Seborrhoeic dermatitis results from a peculiar inflammatory reaction directed to yeasts of the genus Malassezia which are present at the skin surface. The current therapeutic strategies to control episodes of the dermatitis target the yeasts, the host reaction or both. [less ▲]

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See detailLes teignes du cuir chevelu d'ici et d'ailleurs. Quand la prévention est à géographie variable.
Arrese Estrada, Jorge ULiege; Pierard, Claudine ULiege; Pierard, Gérald ULiege

in Revue Médicale de Liège (2003), 58(6), 388-91

Few diseases exhibit such regional variability in their epidemiology, even in an area as limited as Belgium, as tinea capitis. Thus, anthropophilic tinea capitis is highly predominant in areas where new ... [more ▼]

Few diseases exhibit such regional variability in their epidemiology, even in an area as limited as Belgium, as tinea capitis. Thus, anthropophilic tinea capitis is highly predominant in areas where new immigrants from Black Africa and North Africa have settled. By contrast, zoophilic tinea capitis is found largely in areas where the cat population is infected. Kerion often affects professions in which contact with infected livestock is involved. Prevention of tinea capitis thus has distinct regional features. Treatment, on the other hand, has a universal basis. [less ▲]

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See detailLes onychomycoses - Échec et mat?
Arrese Estrada, Jorge ULiege; Quatresooz, Pascale ULiege; Pierard, Claudine ULiege et al

in Revue Médicale de Liège (2003), 58(9), 559-62

According to individuals, onychomycoses or their treatments can be held in check. Some of the "promises" sometimes offered by pharmaceutical companies are not fully kept and hopes of cure may remain wild ... [more ▼]

According to individuals, onychomycoses or their treatments can be held in check. Some of the "promises" sometimes offered by pharmaceutical companies are not fully kept and hopes of cure may remain wild. Some special therapeutic strategies should be employed in case of recalcitrant or recurrent onychomycosis. [less ▲]

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