Publications of Denise JACQUEMIN
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See detailPatient avec un carcinome spinocellulaire cutané localement avancé et métastatique traité par Cemiplimab
Vanhakendover, Louise ULiege; LEBAS, Eve ULiege; Libon, Florence ULiege et al

in Revue Médicale de Liège (2019), (74), 1-5

Le traitement du carcinome spinocellulaire cutané (cSCC) localement avancé et/ou métastasique repose essentiellement sur la chirurgie et, éventuellement, une radiothérapie de la zone chirurgicale et de ... [more ▼]

Le traitement du carcinome spinocellulaire cutané (cSCC) localement avancé et/ou métastasique repose essentiellement sur la chirurgie et, éventuellement, une radiothérapie de la zone chirurgicale et de l’aire ganglionnaire afférente. Malheureusement, certains cas ne sont plus opérables ou accessibles à la radiothérapie et un traitement systémique est alors indiqué. Les chimiothérapies sont peu efficaces et potentiellement toxiques. Une étude récente évaluant l’efficacité et la tolérance du cemiplimab, un antagoniste PD1, dans les cSCC localement avancés et métastasiques démontre une réponse objective confirmée de 49 % et de 47 %, respectivement, avec un maintien de la réponse d’au moins 6 mois de 63 % et de 60 %, respectivement. Nous présentons le cas d’un patient avec un cSCC localement avancé au niveau du front, avec effraction osseuse et adénopathies cervicales, ayant eu de multiples chirurgies et radiothérapies. Il a présenté une réponse partielle au cemiplimab avec un profil de tolérance satisfaisant. [less ▲]

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See detailCarcinome spinocellulaire cutané localement avancé et métastatique traité par cemiplimab.
Vanhakendover, Louise ULiege; LEBAS, Eve ULiege; Libon, Florence ULiege et al

in Revue medicale de Liege (2019), 74(7-8), 436-440

The treatment of locally advanced or metastatic cutaneous squamous cell carcinoma (cSCC) essentially relies on surgery and eventually radiotherapy of the treated site and afferent lymph nodes ... [more ▼]

The treatment of locally advanced or metastatic cutaneous squamous cell carcinoma (cSCC) essentially relies on surgery and eventually radiotherapy of the treated site and afferent lymph nodes. Unfortunately, some cases are no candidates for surgery or radiotherapy and a systemic treatment may be indicated. Chemotherapies are only partially efficacious and associated with potential toxicities. A recent study evaluating the efficacy and tolerance of cemiplimab, a PD1 antagonist for locally advanced and metastatic cSCC demonstrated an objective response rate of 49 % and 47 % for locally advanced and metastatic cSCC, while maintaining a response of at least 6 months of 63 % and 60 %, respectively. We present a clinical case of a patient with a locally advanced cSCC of the forehead with bone resorption and cervical lymphadenopathies. After failure of multiple surgical interventions and radiotherapies, he responded partially to cemiplimab immunotherapy with a good safety profile. [less ▲]

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See detailAlkali injuries may lead to errors of diagnosis and mistreatment (161)
JACQUEMIN, Denise ULiege

Conference (2015, September)

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See detailPurpura fulminans secondaire à une méningococcémie
De Roover, Christophe ULiege; JACQUEMIN, Denise ULiege

in Revue Médicale de Liège (2014), 69(3), 117-118

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See detailA methodological evaluation of volumetric measurement techniques including three-dimensional imaging in breast surgery
HOEFFELIN, Harry; JACQUEMIN, Denise ULiege; Defaweux, Valérie ULiege et al

in BioMed Research International (2014), 2014

Breast surgery currently remains very subjective and each intervention depends on the ability and experience of the operator. To date, no objective measurement of this anatomical region can codify surgery ... [more ▼]

Breast surgery currently remains very subjective and each intervention depends on the ability and experience of the operator. To date, no objective measurement of this anatomical region can codify surgery. In this light, we wanted to compare and validate a new technique for 3D scanning (LifeViz 3D) and its clinical application. Materials and methods. - We tested the use of the 3D LifeViz system (Quantificare) to perform volumetric calculations in various settings ("in situ" in cadaveric dissection, of control prostheses and in clinical patients) and we compared this system to other techniques (CT scanning and Archimedes' principle) under the same conditions. Results. - We were able to identify the benefits (feasibility, safety, portability, low patient stress) and limitations (underestimation of the “in situ” volume, subjectivity of contouring, and patient selection) of the LifeViz 3D system, concluding that the results are comparable with other measurement techniques. Conclusion. - The prospects of this technology seem promising in numerous applications in clinical practice to limit the subjectivity of breast surgery. [less ▲]

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See detailHow a topic treatment can worsen the situation: A new type of iatrogenic "burn".
REMY, Christophe ULiege; LAUNGANI, Alexis; MAGNETTE, André ULiege et al

Poster (2011, September 15)

Many studies showed the high frequency of cutaneous intolerances to ketoprofen but in 85 percent of them, these are photoallergies. The Belgian dematologists published an article a few years ago ... [more ▼]

Many studies showed the high frequency of cutaneous intolerances to ketoprofen but in 85 percent of them, these are photoallergies. The Belgian dematologists published an article a few years ago, demonstrating that it is important to avoid prescription of topical ketoprofen during sunny periods. Our experience showed the risks of lesions without exposing to UV radiations. These gels, on free sale, are widely used by the public. In physiotherapy, they are also regularly used by practitioners who rarely know the risk of photoallergies and often ignore the possibility of burn. In France, many questions have already been asked about these gels and they were even the object of a temporary withdrawal. [less ▲]

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See detailRisk factors for major joints heterotopic ossification after thermal injury
REMY, Christophe ULiege; COLMAN, David ULiege; LEDOUX, Didier ULiege et al

in Burns: Journal of the International Society for Burn Injuries (2009)

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See detailAnalgésie par blocs nerveux périphériques continus dans le cadre des soins de plaies cutanées
Lecoq, Jean-Pierre; Jacquemin, Denise ULiege; Lamy, Maurice ULiege et al

in Revue Médicale de Liège (2008), 63(1), 3-16

We present the case of a patient with a circumferential venous ulcer at the level of the calf. She is hospitalized for surgical treatment by continuous aspiration dressing and coverage with skin graft ... [more ▼]

We present the case of a patient with a circumferential venous ulcer at the level of the calf. She is hospitalized for surgical treatment by continuous aspiration dressing and coverage with skin graft. This patient presents a history of chronic pain, on which classical medications have few effects and are accompanied by side effects. After discussion with the patient, a double continuous peripheral nervous block (femoral and sciatic nerve) is set up to improve the tolerance to wound dressing. This technique presents favorable antalgic results. The indications and the different techniques of block performance (by electrostimulation or echo-guided) are described. The infectious risks related to the presence of catheter near cutaneous wounds are clarified according to recent data of literature. The relevance of these techniques in correlation with the development of chronic pain and on the trophicity of the wounds are also discussed. [less ▲]

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See detailLe cas clinique du mois. Carcinome basocellulaire pédicule et pigmenté: une présentation inhabituelle.
Azzam, C.; Arrese Estrada, Jorge ULiege; Jacquemin, Denise ULiege et al

in Revue Médicale de Liège (2006), 61(9), 614-6

Basal cell carcinomas (BCC) are the most common malignant neoplasms in humans. Clinical misdiagnoses are not uncommon. These cancers are classified according to their histological and clinical ... [more ▼]

Basal cell carcinomas (BCC) are the most common malignant neoplasms in humans. Clinical misdiagnoses are not uncommon. These cancers are classified according to their histological and clinical characteristics which exhibit distinct malignant behaviours. It is important to be aware of the different clinical presentations both for the accurate diagnosis and tumour management. We report the case of a 78-year-old man, who presented an unusual pedunculated and pigmented BCC. This combined aspect is rarely encountered. [less ▲]

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