Publications and communications of Luiz Carlos Maia Ladeira

Books published as author or co-author

Wittwehr, C., Audouze, K., Burgdorf, T., Clerbaux, L.-A., Coerek, E., DEMUYNCK, E., EXNER, T., FILIPOVSKA, J., FRITSCHE, E., Geris, L., HENCH, V., JELIAZKOVA, N., KARSCHNIK, T., KYCHOVSKA, E., Maia Ladeira, L. C., MALINOWSKA, J., MARINOV, E., MARTENS, M., MERTENS, B., ... VIVIANI, B. (2025). SKIG report 2023-2024: Society for the Advancement of AOPs Knowledgebase Interest Group. Lu: Publications Office of the European Union. doi:10.2760/7749010

Articles accepted in reviewed journal

Niarakis, A., An, G., Maia Ladeira, L. C., Hiroi, N. F., Papadopoulou, A., Crawley, F. P., Nikaein, N., Calzone, L., Tsirvouli, E., Balci, H., Medina, M. E., Veschini, L., Ozisik, O., Messina, F., Marku, M., Tran, V. D. T., Montagud, A., Schlosserova, N., Subbannayya, Y., ... Laubenbacher, R. (16 September 2025). Building Immune Digital Twins: An International and Transdisciplinary Community Effort. ImmunoInformatics, 20, 100060. doi:10.1016/j.immuno.2025.100060

Bwanya, B., Lodhi, S., de Kok, T. M., Maia Ladeira, L. C., Verheijen, M. C., Jennen, D. G., & Caiment, F. (2025). Machine learning classification of steatogenic compounds using toxicogenomics profiles. Toxicology, 154237. doi:10.1016/j.tox.2025.154237

Maia Ladeira, L. C., Verhoeven, A., van Ertvelde, J., Jiang, J., Gamba, A., Sanz-Serrano, J., Vanhaecke, T., Heusinkveld, H. J., Jover, R., Vinken, M., Geris, L., & Staumont, B. (07 July 2025). Unlocking liver physiology: comprehensive pathway maps for mechanistic understanding. Frontiers in Toxicology, 7. doi:10.3389/ftox.2025.1619651

Maertens, A., Kincaid, B., Bridgeford, E., Brochot, C., de Carvalho E Silva, A., Dorne, J.-L. C. M., Geris, L., Husøy, T., Kleinstreuer, N., Maia Ladeira, L. C., Middleton, A., Reynolds, J., Rodriguez, B., Roggen, E. L., Russo, G., Thayer, K., & Hartung, T. (2025). From cellular perturbation to probabilistic risk assessments. ALTEX: Alternatives to Animal Experimentation, 42 (3), 413 - 434. doi:10.14573/altex.2501291

Maia Ladeira, L. C., Damasceno, E. M., de Melo, A. L. D. A. B., da Silva, J., Maldonado, I. R. D. S. C., & da Matta, S. L. P. (2025). Anti-adiposity effect of cipó-cravo (Tynanthus fasciculatus), a vine from the Brazilian Atlantic Forest. Revista Brasileira de Plantas Medicinais, 27 (1), 2025001. doi:10.70151/vkvqrt21

Messina, F., Rotondo, C., Maia Ladeira, L. C., Crosetti, S., Properzi, M., Dimartino, V., Riccitelli, B., Staumont, B., Chillemi, G., Geris, L., Bocci, M. G., & Fontana, C. (2025). Molecular exploration of host-pathogen interactions in severe Pseudomonas aeruginosa infection through a multi-level data integration approach. Frontiers in Medicine, Volume 12 - 2025. doi:10.3389/fmed.2025.1600509

Staumont, B., Maia Ladeira, L. C., Gamba, A., Heusinkveld, H. J., Piersma, A., Fritsche, E., Masereeuw, R., Vanhaecke, T., Teunis, M., Luechtefeld, T., Hartung, T., Jover, R., Vinken, M., & Geris, L. (2025). Mapping physiology: a systems biology approach for the development of alternative methods in toxicology. ALTEX: Alternatives to Animal Experimentation. doi:10.14573/altex.2412241

Niarakis, A., Laubenbacher, R., An, G., Ilan, Y., Fisher, J., Flobak, Å., Reiche, K., Rodríguez Martínez, M., Geris, L., Maia Ladeira, L. C., Veschini, L., Blinov, M. L., Messina, F., Fonseca, L. L., Ferreira, S., Montagud, A., Noël, V., Marku, M., Tsirvouli, E., ... Glazier, J. A. (30 November 2024). Immune digital twins for complex human pathologies: applications, limitations, and challenges. NPJ Systems Biology and Applications, 10 (1), 141. doi:10.1038/s41540-024-00450-5

Dias, F. C. R., Cupertino, M. C., Silva, P. G., Oliveira, E. L., Maia Ladeira, L. C., Matta, S. L. P., Otoni, W. C., & Gomes, M. L. M. (2023). Exposure to Pfaffia glomerata causes oxidative stress and triggers hepatic changes. Brazilian Journal of Biology, 83, 271425. doi:10.1590/1519-6984.271425

de Paula Dias Moreira, L., Enes, B. R. N., de São José, V. C. P. B., Toledo, R. C. L., Maia Ladeira, L. C., Cardoso, R. R., da Silva Duarte, V. C., Hermsdorff, H. H. M., de Barros, F. A. R., & Martino, H. R. S. D. (21 January 2022). Chia (Salvia hispanica L.) Flour and Oil Ameliorate Metabolic Disorders in the Liver of Rats Fed a High-Fat and High Fructose Diet. Foods, 11 (3), 285. doi:10.3390/foods11030285

Castro, T. L. P. A. E., Maia Ladeira, L. C., Santos, C. F. F., de Deus, F. A. N., Gomes, A. R., Bastos, D. S. S., Souza, A. C. U. F., & dos Santos, E. R. C. (27 July 2021). Chronic caffeine use does not influence behavior and brain oxidative status in mice. Revista da Associação Brasileira de Nutrição, 12 (2), 146–166. doi:10.47320/rasbran.2021.2014

Maia Ladeira, L. C., dos Santos, E. R. C., Santos, T. A., da Silva, J., Lima, G. D. D. A., Machado-Neves, M., da Silva, R. C., Freitas, M. B., & Maldonado, I. R. D. S. C. (28 June 2021). Green tea infusion prevents diabetic nephropathy aggravation in recent-onset type 1 diabetes regardless of glycemic control. Journal of Ethnopharmacology, 274 (January), 114032. doi:10.1016/j.jep.2021.114032

MARRIEL, N. B., Maia Ladeira, L. C., ARAÚJO, R. D. S., da SILVA, J., MARTINS, A. L. P., & TAVARES, M. G. (08 June 2021). Playfulness in the Teaching of Cell Biology: possibilities in higher education. Elo, 10, 1–11. doi:10.21284/elo.v10i.12290

Maia Ladeira, L. C., dos Santos, E. R. C., Valente, G. E., da Silva, J., Santos, T. A., & dos Santos Costa Maldonado, I. R. (25 October 2019). Could biological tissue preservation methods change chemical elements proportion measured by energy dispersive X-ray spectroscopy? Biological Trace Element Research, 196 (1), 168–172. doi:10.1007/s12011-019-01909-x

Articles accepted in conference proceedings

Maia Ladeira, L. C., Geris, L., & Staumont, B. (2025). Building knowledge maps to support NAM development. ALTEX: Alternatives to Animal Experimentation, 13 (2), 346.

Maia Ladeira, L. C., Kuchovska, E., Sanz-Serrano, J., Steinbach, A., Corradi, M., Ortega-Valbona, R., Pobis, P., Cöllen, E., Khalidi, H., Glasgow, S., Hayot, G., Martinez, R., Islam, B., Veltman, C., Zajac, J., Ormanin-Lewandowska, A., Moné, M., Kandarova, H., Tangianu, S., ... Busquet, F. (2025). ASPIS academy for sustainable toxicology through NAMs. ALTEX: Alternatives to Animal Experimentation, 13 (2). doi:10.58847/ap.2502

Pobis, P., Kuchovska, E., Maia Ladeira, L. C., Sanz-Serrano, J., Steinbach, A., Corradi, M., Ortega-Valbona, R., Cöllen, E., Khalidi, H., Glasgow, S., Hayot, G., Martinez, R., Islam, B., Veltman, C. J., Zajac, J., Ormanin-Lewandowska, A., Moné, M., Kandarova, H., Tangianu, S., ... Pallocca, G. (2025). ASPIS academy: Early-stage researchers in next-generation toxicology. ALTEX: Alternatives to Animal Experimentation, 13 (2), 324.

Barnes, D., Irvine, A., Gamba, A., Maia Ladeira, L. C., Staumont, B., Yang, H., Steffensen, I.-L., Geris, L., Janssen, M., & Masereeuw, R. (2022). Development of an adverse outcome pathway for kidney tubular necrosis. In Helena Kandarova & João Barroso, 21st International Congress ESTIV Abstract Book. Bratslava, Slovakia: ESTIV.

Berkhout, J., Piersma, A., Legler, J., Gamba, A., Maia Ladeira, L. C., Staumont, B., Lesage, R. L., Geris, L., & Heuseinkveld, H. (2022). Computational modelling of neural tube closure defects. In Helena Kandarova & João Barroso, 21st International Congress ESTIV Abstract Book. Bratslava, Slovakia: ESTIV.

Maia Ladeira, L. C., Gamba, A., Lesage, R. L., Verhoeven, A., van Ertvelde, J., Jiang, J., Roodzant, D. L., Teunis, M., Jover, R., Vanhaecke, T., Vinken, M., Heuseinkveld, H., Geris, L., & Staumont, B. (2022). Designing physiological maps as a tool to study liver toxicology. In Helena Kandarova & João Barroso, 21st International Congress ESTIV Abstract Book. Bratslava, Slovakia: ESTIV.

Gamba, A., Maia Ladeira, L. C., Lesage, R. L., Roodzant, D. L., Barnes, D. A., Janssen, M. J., Teunis, M., Masereeuw, R., Geris, L., & Staumont, B. (2022). From Physiological Map to Ontology Unravelling Kidney Toxicity. In VPHi, VPH2022 Virtual Physiological Human Conference. Brussels, Belgium: VPHi.

Maia Ladeira, L. C., Gamba, A., Lesage, R. L., Verhoeven, A., Jiang, J., van Ertvelde, J., Jover, R., Vanhaecke, T., Mathieu, V., Geris, L., & Staumont, B. (2022). Developing a physiological map as a framework to study chemical- induced liver steatosis. In VPHi, VPH2022 Virtual Physiological Human Conference. Brussels, Belgium: VPHi.

Posters presentations in conferences with scientific selection committee

Kuchovska, E., Gamba, A., Maia Ladeira, L. C., Staumont, B., Lesage, R. L., Steffensen, I.-L., Soop, G. L., Hofer, T., Myhre, O., Dirven, H., Geris, L., & Fritsche, E. (24 November 2022). FIRST STEPS FOR CREATING AN ONTOLOGY FOR COGNITIVE FUNCTION DEFECTS FOR REGULATORY APPLICATION [Poster presentation]. 21st International Congress ESTIV, Sitges, Spain.

Maia Ladeira, L. C.* , Gamba, A.* , Lesage, R., Kuchovska, E., Görts, N., Verhoeven, A., Jiang, J., van Ertvelde, J., Barnes, D., Janssen, M., Berkhout, J., Roodzant, D., Teunis, M., Bozada, T. J., Luechtefeld, T., Jover, R., Vanhaecke, T., Vinken, M., Masereeuw, R., ... Staumont, B. (24 November 2022). Physiological maps and chemical-induced disease ontologies: tools to support NAMs development for next-generation risk assessment [Poster presentation]. ASPIS Open Symposium, Sitges, Spain.
* These authors have contributed equally to this work.

Gamba, A., Maia Ladeira, L. C., Lesage, R., Roodzant, D., Barnes, D., Janssen, M., Teunis, M., Masereeuw, R., Geris, L., & Staumont, B. (20 October 2022). Physiological map to study kidney toxicity in the ONTOX project [Poster presentation]. 21st International Congress ESTIV, Sitges, Spain.

Preprints

Messina, F., Rotondo, C., Maia Ladeira, L. C., Properzi, M., Dimartino, V., Riccitelli, B., Staumont, B., Chilemi, G., Geris, L., Bocci, M. G., & Fontana, C. (2024). Building a model of sepsis: data integration unravels pathogenic mechanisms in severe P. aeruginosa infections. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/327015. doi:10.1101/2024.10.17.618881