Rademaker, G., Hernandez, G. A., Seo, Y., Dahal, S., Miller-Phillips, L., Li, A. L., Peng, X. L., Luan, C., Qiu, L., Liégeois, M., Wang, B., Wen, K. W., Kim, G. E., Collisson, E. A., Kruger, S. F., Boeck, S., Ormanns, S., Guenther, M., Heinemann, V., ... Perera, R. M. (2025). PCSK9 drives sterol-dependent metastatic organ choice in pancreatic cancer. Nature. doi:10.1038/s41586-025-09017-8 |
Liégeois, M., Hsieh, A., Al-Fouadi, M., Charbit, A. R., Yang, C. X., Hackett, T.-L., & Fahy, J. V. (17 March 2025). Cellular and molecular features of asthma mucus plugs provide clues about their formation and persistence. Journal of Clinical Investigation, 135 (6). doi:10.1172/JCI186889 |
Liégeois, M., Braunreuther, M., Charbit, A. R., Raymond, W. W., Tang, M., Woodruff, P. G., Christenson, S. A., Castro, M., Erzurum, S. C., Israel, E., Jarjour, N. N., Levy, B. D., Moore, W. C., Wenzel, S. E., Fuller, G. G., & Fahy, J. V. (18 June 2024). Peroxidase-mediated mucin cross-linking drives pathologic mucus gel formation in IL-13-stimulated airway epithelial cells. JCI Insight, 9 (15). doi:10.1172/jci.insight.181024 |
Charbit, A. R., Liégeois, M., Raymond, W. W., Comhair, S. A. A., Johansson, M. W., Hastie, A. T., Bleecker, E. R., Fajt, M., Castro, M., Sumino, K., Erzurum, S. C., Israel, E., Jarjour, N. N., Mauger, D. T., Moore, W. C., Wenzel, S. E., Woodruff, P. G., Levy, B. D., Tang, M. C., & Fahy, J. V. (01 June 2024). A novel DNase assay reveals low DNase activity in severe asthma. American Journal of Physiology - Lung Cellular and Molecular Physiology, 326 (6), 796 - L804. doi:10.1152/ajplung.00081.2024 |
Everman, J. L., Sajuthi, S. P., Liégeois, M., Jackson, N. D., Collet, E. H., Peters, M. C., Chioccioli, M., Moore, C. M., Patel, B. B., Dyjack, N., Powell, R., Rios, C., Montgomery, M. T., Eng, C., Elhawary, J. R., Mak, A. C. Y., Hu, D., Huntsman, S., Salazar, S., ... Seibold, M. A. (09 May 2024). A common polymorphism in the Intelectin-1 gene influences mucus plugging in severe asthma. Nature Communications, 15 (1), 3900. doi:10.1038/s41467-024-48034-5 |
Legrand, C., Vanneste, D., Hego, A., Sabatel, C., Mollers, K., Schyns, J., Maréchal, P., Abinet, J., Tytgat, A., Liégeois, M., Polese, B., Meunier, M., Radermecker, C., Fievez, L., Bureau, F., & Marichal, T. (2024). Lung Interstitial Macrophages Can Present Soluble Antigens and Induce Foxp3+ Regulatory T Cells. American Journal of Respiratory Cell and Molecular Biology. doi:10.1165/rcmb.2023-0254OC |
Rademaker, G.* , Boumahd, Y.* , Peiffer, R., Anania, S., Wissocq, T., Liégeois, M., Luis, G., Sounni, N. E., Agirman, F., Maloujahmoum, N., De Tullio, P., Thiry, M., Bellahcene, A., Castronovo, V., & Peulen, O. (July 2022). Myoferlin targeting triggers mitophagy and primes ferroptosis in pancreatic cancer cells. Redox Biology, 53, 102324. doi:10.1016/j.redox.2022.102324 * These authors have contributed equally to this work. |
Liégeois, M., & Fahy, J. V. (01 April 2022). The Mucin Gene MUC5B Is Required for Normal Lung Function. American Journal of Respiratory and Critical Care Medicine, 205 (7), 737 - 739. doi:10.1164/rccm.202201-0064ED |
Liégeois, M., Bai, Q., Fievez, L., Pirottin, D., Legrand, C., Guiot, J., Schleich, F., Corhay, J.-L., Louis, R., Marichal, T., & Bureau, F. (2022). Airway Macrophages Encompass Transcriptionally and Functionally Distinct Subsets Altered by Smoking. American Journal of Respiratory Cell and Molecular Biology, 67 (2), 241 - 252. doi:10.1165/rcmb.2021-0563OC |
Liégeois, M.* , Legrand, C.* , Desmet, C.* , Marichal, T.* , & Bureau, F.*. (2018). The interstitial macrophage: A long-neglected piece in the puzzle of lung immunity. Cellular Immunology, 330, 91-96. doi:10.1016/j.cellimm.2018.02.001 * These authors have contributed equally to this work. |