Publications and communications of Jean-Christophe Monbaliu

Hellwig, H., Bovy, L., Van Hecke, K., Vlaar, C. P., Romañach, R. J., Noor-E-Alam, M., Myerson, A. S., Stelzer, T., & Monbaliu, J.-C. (2025). Continuous Flow Synthesis of Nitrofuran Pharmaceuticals Using Acetyl Nitrate. Angewandte Chemie International Edition, 202501660. doi:10.1002/anie.202501660

Monbaliu, J.-C., Muzyka, C., & Renson, S. (12 September 2024). Continuous-flow process for the production of glycerol carbonate.

Monbaliu, J.-C., Muzyka, C., & Renson, S. (04 September 2024). Continuous-flow process for the production of glycerol carbonate.

Bianchi, P., & Monbaliu, J.-C. (06 August 2024). New Opportunities for Organic Synthesis with Superheated Flow Chemistry. Accounts of Chemical Research, 57 (15), 2207 - 2218. doi:10.1021/acs.accounts.4c00340

Zimmermann, L., Lee, H. L., Koishybay, A., Vlaar, C. P., Monbaliu, J.-C., Romañach, R. J., Noor-E-Alam, M., Myerson, A. S., & Stelzer, T. (13 June 2024). Measurements and Correlation of Timolol Maleate Solubility in Biobased Neat and Binary Solvent Mixtures. Journal of Chemical and Engineering Data, 69 (6), 2369 - 2379. doi:10.1021/acs.jced.4c00060

Mbodji, A., Agrawal, S., Mulero Cruz, K., Perez-Molares, D., Vlaar, C., Duconge, J., Monbaliu, J.-C., & Stelzer, T. (2024). Solubility Measurements and Correlation of Modafinil in Neat Solvents and Binary Solvent Mixtures. Journal of Chemical and Engineering Data. doi:10.1021/acs.jced.3c00738

Chen, Y., & Monbaliu, J.-C. (2024). Preparation of Dinitrogen Trioxide for Organic Synthesis: A Phase Equilibrium Approach. Chemistry, 202303516. doi:10.1002/chem.202303516

Muzyka, C., Renson, S., Grignard, B., Detrembleur, C., & Monbaliu, J.-C. (2024). Intensified Continuous Flow Process for the Scalable Production of Bio-Based Glycerol Carbonate. Angewandte Chemie International Edition, 202319060. doi:10.1002/anie.202319060

Bovy, L., & Monbaliu, J.-C. (2024). A perspective on the synthetic potential of biobased building blocks for heterocyclic chemistry. Advances in Heterocyclic Chemistry. doi:10.1016/bs.aihch.2024.04.003

Monbaliu, J.-C. (2024). On the synergy between in silico approaches and flow [Paper presentation]. Flow Chemistry Europe 2024 Malaga, Malaga, Spain.

Petit, G., Malherbe, C., Bianchi, P., & Monbaliu, J.-C. (2024). Innovative Chalcogenide Transfer Agent for Improved Aqueous Quantum Dot Synthesis. Chemical Science. doi:10.1039/d4sc01135j

Rodríguez-Fernández, K., Reynaldo-Fernández, G., Reyes-González, S., De Las Barreras, C., Rodríguez-Vera, L., Vlaar, C., Monbaliu, J.-C., Stelzer, T., Duconge, J., & Mangas-Sanjuan, V. (2024). New insights into the role of VKORC1 polymorphisms for optimal warfarin dose selection in Caribbean Hispanic patients through an external validation of a population PK/PD model. Biomedicine and Pharmacotherapy, 170, 115977. doi:10.1016/j.biopha.2023.115977

Silva Brenes, D. V., Reyes-Vargas, S. K., Duconge, J., Vlaar, C., Stelzer, T., & Monbaliu, J.-C. (2024). Continuous Flow Intensification for the Synthesis of High-Purity Warfarin. Organic Process Research and Development. doi:10.1021/acs.oprd.3c00338

Tsai, Y.-H., Cattoen, M., Masson, G., Christen, G., Traber, L., Donnard, M., Leroux, F. R., Bentzinger, G., Guizzetti, S., & Monbaliu, J.-C. (2024). On a seamlessly replicable circular photoreactor for lab-scale continuous flow applications. Reaction Chemistry and Engineering. doi:10.1039/d4re00109e

Bianchi, P., & Monbaliu, J.-C. (2023). Revisiting the Paradigm of Reaction Optimization in Flow with a Priori Computational Reaction Intelligence. Angewandte Chemie International Edition, 202311526. doi:10.1002/anie.202311526

Monbaliu, J.-C., & Len, C. (June 2023). Editorial. Journal of Flow Chemistry, 13 (2), 75. doi:10.1007/s41981-023-00276-y

Boddaert, M.* , Bianchi, P.* , Silva Brenes, D. V., Musina, A., Winter, M., Roth, P., Renard, P.-Y., Legros, J., & Monbaliu, J.-C. (2023). Miniaturized Ozonolysis Flow Platform for Expeditious Sulfur Mustard Warfare Simulant Neutralization. Green Chemistry. doi:10.1039/d3gc03470d
* These authors have contributed equally to this work.

Chen, Y., Renson, S., & Monbaliu, J.-C. (10 October 2022). On Demand Flow Platform for the Generation of Anhydrous Dinitrogen Trioxide and Its Further Use in N-Nitrosative Reactions. Angewandte Chemie International Edition, 61 (41), 202210146. doi:10.1002/anie.202210146

Morodo Martinez, R., Riva, R., van den Akker, N. M. S., Molin, D. G. M., Jérôme, C., & Monbaliu, J.-C. (2022). Accelerating the end-to-end production of cyclic phosphate monomers with modular flow chemistry. Chemical Science. doi:10.1039/d2sc02891c

Toupy, T., Bovy, L., & Monbaliu, J.-C. (2022). Continuous flow organocatalyzed methoxycarbonylation of benzyl alcohol derivatives with dimethyl carbonate. Journal of Flow Chemistry. doi:10.1007/s41981-022-00216-2

Campalani, C., Petit, G., Monbaliu, J.-C., Selva, M., & Perosa, A. (2022). Continuous flow photooxidative degradation of water pollutants with fish waste-derived carbon dots [Paper presentation]. Merck Young Chemists Symposium.

Kassin, V.-E., Silva-Brenes, D. V., Bernard, T., Legros, J., & Monbaliu, J.-C. (2022). A continuous flow generator of organic hypochlorites for the neutralization of chemical warfare agent simulants. Green Chemistry. doi:10.1039/d2gc00458e

Monbaliu, J.-C. (08 January 2021). Development of low footprint processes with hazardous chemicals [Paper presentation]. 11th CVCC Annual Meeting, Montréal, Canada.

Monbaliu, J.-C. (2021). Reactions with molecular oxygen: from the preparation of active pharmaceuticals to the neutralization of chemical warfare agents [Paper presentation]. Corning Advanced Flow Reactor Technologies Webinars.

Monbaliu, J.-C. (2021). Introduction to continuous flow chemistry with recent examples from API manufacturing [Paper presentation]. PhD seminars at the Kaunas University of Technology, Kaunas, Latvia.

Monbaliu, J.-C., Gauron, G., & Adamo, A. (2021). Handling toxic and unstable intermediates. The optimum chemistry with the right technology [Paper presentation]. Corning Advanced Flow Reactor Technologies Webinar.

Monbaliu, J.-C. (December 2020). Advanced continuous flow strategies for the preparation of high valued-added targets [Paper presentation]. Transition énergétique et chimie durable.

Monbaliu, J.-C. (29 October 2020). Continuous flow upgrading of biobased platforms [Paper presentation]. Greenwin's Master Sessions: Green Chemistry and White Biotechnology.

Mendoza Gallego, C., Désert, A., Chateau, D., Monnerau, C., Khrouz, L., Lerouge, F., Andraud, C., Monbaliu, J.-C., Parola, S., & Heinrichs, B. (11 September 2020). Au Nanobipyramids@mSiO2 Core-Shell Nanoparticles for Plasmon-Enhanced Singlet Oxygen Photooxygenations in Segmented Flow Microreactors. Nanoscale Advances, 2, 5280-5287. doi:10.1039/D0NA00533A

Lemos, A., Trump, L., Lallemand, B., Pasau, P., Mercier, J., Lemaire, C., Monbaliu, J.-C., Genicot, C., & Luxen, A. (March 2020). Radical c–h18f-difluoromethylation of heteroarenes with [18f]difluoromethyl heteroaryl-sulfones by visible light photoredox catalysis. Catalysts, 10 (3), 275. doi:10.3390/catal10030275

Bianchi, P., Petit, G., & Monbaliu, J.-C. (December 2019). Continuous flow technology for the photochemical synthesis of spherical gold nanoparticles [Poster presentation]. Merck Organic Chemistry Symposium, Blankenberg, Belgium.

Emonds-Alt, G.* , Mignolet, B.* , Malherbe, C., Monbaliu, J.-C., Remacle, F., & Eppe, G. (2019). Understanding chemical interaction between phosphonate-derivative molecules and silver surface cluster in SERS: a combined experimental and computational approach. Physical Chemistry Chemical Physics. doi:10.1039/C9CP01615E
* These authors have contributed equally to this work.

Pelzer, M., Pirard, S. L., Páez, C. A., Monbaliu, J.-C., & Heinrichs, B. (2019). Development of a Continuous Fluidic Reactor for the Photocatalytic Treatment of Liquid Effluents. Journal of Materials Science and Nanotechnology, 7 (3), 19.

Toupy, T., Ollivier, N., Melnyk, O., & Monbaliu, J.-C. (06 December 2018). Accelerated Microfluidic Native Chemical Ligation at Difficult Amino Acids Towards Cyclic Peptides [Poster presentation]. Merck Organic Chemistry Symposium.

Mendoza Gallego, C., Emmanuel, N., Pàez Martinez, C., Dreesen, L., Monbaliu, J.-C., & Heinrichs, B. (21 May 2018). Transitioning from conventional batch to microfluidic processes for the efficient singlet oxygen photooxygenation of methionine [Poster presentation]. ISCRE25 25th International Conference on Chemical Reaction Engineering "Bridging Science and Technology", Florence, Italy.

Emmanuel, N., Mendoza Gallego, C., Heinrichs, B., Dreesen, L., Monbaliu, J.-C., Vizza, A., Horn, C., & Winter, M. (12 March 2018). Integrated continuous flow photoreactors: Photooxidation with singlet oxygen [Poster presentation]. Ecole doctorale thématique Synth_Flux.

Monbaliu, J.-C. (07 February 2018). Boosting multistep synthetic organic chemistry with Corning Advanced-Flow Reactors [Paper presentation]. Flow Chemistry Europe 2018: Technologies, Companies and Commercialization, Cambridge, United Kingdom.

Emmanuel, N., Mendoza Gallego, C., Winter, M., Horn, C., Vizza, A., Dreesen, L., Heinrichs, B., & Monbaliu, J.-C. (06 February 2018). Integrated continuous flow photoreactors: Photooxidation of (L)-methionine with singlet oxygen [Poster presentation]. Noémie Emmanuel, 4031 Angleur, Belgium.

Emonds-Alt, G., Mignolet, B., Malherbe, C., Monbaliu, J.-C., Remacle, F., & Eppe, G. (2018). A combined study of the binding of Glyphosate on silver nanoparticles and implications for SERS [Poster presentation]. Journée de département 2018.

Ollivier, N.* , Toupy, T.* , Hartkoorn, R., Desmet, R., Monbaliu, J.-C.* , & Melnyk, O.*. (2018). Accelerated microfluidic native chemical ligation at difficult amino acids toward cyclic peptides. Nature Communications, 9, 2847. doi:10.1038/s41467-018-05264-8
* These authors have contributed equally to this work.

Emmanuel, N., Mendoza Gallego, C., Heinrichs, B., Dreesen, L., Monbaliu, J.-C., Vizza, A., Horn, C., & Winter, M. (07 December 2017). Integrated continuous flow photoreactors: Photooxidation with singlet oxygen [Poster presentation]. Merck Organic Chemistry Symposium 2017.

Emmanuel, N., Monbaliu, J.-C., Winter, M., Horn, C., & Vizza, A. (07 December 2017). Integrated continuous flow photoreactors: Photooxidation with singlet oxygen [Paper presentation]. Merck Organic Chemistry Symposium 2017.

Emmanuel, N., & Monbaliu, J.-C. (06 July 2017). Integrated continuous flow photoreactors: Photooxidation of (L)-methionine with singlet oxygen [Paper presentation]. Journée du département de chimie de l'ULiège.

Emmanuel, N., & Monbaliu, J.-C. (09 May 2017). Integrated continuous flow photoreactors: Photooxidation of (L)-methionine derivatives with singlet oxygen [Paper presentation]. EDT Chim 2017.

Monbaliu, J.-C. (27 April 2017). Reinventing chemical manufacturing: toward a compact and mobile factory? [Paper presentation]. Liège créative, Liège, Belgium.

Monbaliu, J.-C. (20 April 2017). Expanding chemistry's horizon with continuous-flow reactors - part II [Paper presentation]. Solvay Workshop on "Chemical reactions and separation in flows", Brussels, Belgium.

Emmanuel, N., Mendoza Gallego, C., Lismont, M., Dreesen, L., Heinrichs, B., & Monbaliu, J.-C. (31 March 2017). Integrated continuous-flow photoreactors: Photooxidation of (L)-methionine with singlet oxygen [Poster presentation]. Journée-Rencontre des Jeunes Chimistes, Louvain, Belgium.

Monbaliu, J.-C. (2017). Expanding Chemistry’s Horizon with Continuous-Flow Reactors - part III [Paper presentation]. EuCheMS Young Investigator Workshop, Cologne, Germany.

Emmanuel, N., Mendoza Gallego, C., Lismont, M., Dreesen, L., Heinrichs, B., & Monbaliu, J.-C. (08 December 2016). Integrated continuous flow photoreactors: Photooxidation of (L)-methionine with singlet oxygen [Poster presentation]. 20th Sigma-Aldrich Symposium, Blankenberge, Belgium.

Emmanuel, N., Mendoza Gallego, C., Lismont, M., Dreesen, L., Heinrichs, B., & Monbaliu, J.-C. (13 October 2016). Integrated continuous flow photoreactors: Photooxidation of (L)-methionine with singlet oxygen [Poster presentation]. Journée Scientifique SRC 2016, Liège, Belgium.

Raibaut, L.* , Cargoët, M.* , Ollivier, N., Chang, Y. M., Drobecq, H., Boll, E., Desmet, R., Monbaliu, J.-C.* , & Melnyk, O.*. (2016). Accelerating chemoselective peptide bond formation using bis(2-selenylethyl)amido peptide selenoester surrogates. Chemical Science. doi:10.1039/C5SC03459K
* These authors have contributed equally to this work.

Lamborelle, N., Monbaliu, J.-C., Simon, J., Joris, B., & Luxen, A. (June 2015). Enantioselective Synthesis of Vinyglycine Derivatives Using Continuous-Flow Thermolysis for Meso- Diaminopimelic Acid Preparation [Poster presentation]. Biomedica 2015, Genk, Belgium.

Henneuse, C., & Monbaliu, J.-C. (May 2014). L'intensification des procédés chimiques, une approche radicale. Athena, 391, p. 18-21.

Monbaliu, J.-C. (2014). L'asymétrie en chimie organique: Des effets non-linéaires jusqu'à l'apparition de la vie. Bulletin de la Société Royale des Sciences de Liège, 15104-15107.

Monbaliu, J.-C., Beagle, L., Hansen, F., Stevens, C., McArdle, C., & Katritzky, A. (2013). Capture of benzotriazole-based Mannich electrophiles by CH-acidic compounds. RSC Advances, 3, 4152-4155. doi:10.1039/c3ra22826f

Monbaliu, J.-C., Beagle, L., Kovacs, J., Zeller, M., Stevens, C., & Katritzky, A. (2012). En route towards α-benzotriazoyl nitroso derivatives. RSC Advances, 2, 8941-8945. doi:10.1039/c2ra21311g

Monbaliu, J.-C., Dive, G., Marchand-Brynaert, J., & Peeters, D. (2010). HDA cycloadditions of 1-diethoxyphosphonyl-1,3-butadiene with nitroso heterodienophiles: a computational investigation. Journal of Molecular Structure: Theochem, 959, 49-54. doi:10.1016/j.theochem.2010.08.004