Publications and communications of Gabriel Mazzucchelli

Gobbi Amorim, F., Redureau, D., Crasset, T., Freuville, L., Baiwir, D., Mazzucchelli, G., Menzies, S. K., Casewell, N. R., & Quinton, L. (25 May 2023). Next-Generation Sequencing for Venomics: Application of Multi-Enzymatic Limited Digestion for Inventorying the Snake Venom Arsenal. Toxins, 15 (6), 357. doi:10.3390/toxins15060357

Papadopoulos, N., Nédélec, A., Derenne, A., Şulea, T. A., Pecquet, C., Chachoua, I., Vertenoeil, G., Tilmant, T., Petrescu, A.-J., Mazzucchelli, G., Iorga, B. I., Vertommen, D., & Constantinescu, S. N. (05 April 2023). Oncogenic CALR mutant C-terminus mediates dual binding to the thrombopoietin receptor triggering complex dimerization and activation. Nature Communications, 14 (1), 1881. doi:10.1038/s41467-023-37277-3

Martinet, L., Naômé, A., Rezende, L. C. D., Tellatin, D., Pignon, B., Docquier, J.-D., Sannio, F., Baiwir, D., Mazzucchelli, G., Frederich, M., & Rigali, S. (06 January 2023). Lunaemycins, New Cyclic Hexapeptide Antibiotics from the Cave Moonmilk-Dweller Streptomyces lunaelactis MM109T. International Journal of Molecular Sciences, 24 (2), 1114. doi:10.3390/ijms24021114

Grifnee, E., Kune, C., Delvaux, C., Quinton, L., Matagne, A., Mazzucchelli, G., Far, J., & De Pauw, E. (29 August 2022). Investigation of structure-stabilizing elements in proteins by ion mobility mass spectrometry and collision-induced unfolding [Poster presentation]. IMSC.

Burat, B., Reynaerts, A., Baiwir, D., Fleron, M., Gohy, S., Eppe, G., Leal, T.* , & Mazzucchelli, G.*. (31 July 2022). Sweat Proteomics in Cystic Fibrosis: Discovering Companion Biomarkers for Precision Medicine and Therapeutic Development. Cells, 11 (15), 2358. doi:10.3390/cells11152358
* These authors have contributed equally to this work.

Martinet, L., Baiwir, D., Mazzucchelli, G., & Rigali, S. (26 May 2022). Structure of New Ferroverdins Recruiting Unconventional Ferrous Iron Chelating Agents. Biomolecules, 12 (6), 752. doi:10.3390/biom12060752

Gillot, L., Lebeau, A., Baudin, L., POTTIER, C., Louis, T., Durré, T., Longuespée, R., Mazzucchelli, G., NIZET, C., BLACHER, S., KRIDELKA, F., & Noël, A. (14 May 2022). Periostin in lymph node pre-metastatic niches governs lymphatic endothelial cell functions and metastatic colonization. Cellular and Molecular Life Sciences, 79 (6), 295. doi:10.1007/s00018-022-04262-w

Lebeau, A.* , Bruyère, D.* , RONCARATI, P., Peixoto, P., Hervouet, E., COBRAIVILLE, G., Taminiau, B., Masson, M., Gallego, C., Mazzucchelli, G., Smargiasso, N., Fleron, M., Baiwir, D., Hendrick, E., Pilard, C., Lerho, T., Reynders, C., Ancion, M., GREIMERS, R., ... Herfs, M. (28 February 2022). HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources. Nature Communications, 13 (1), 1076. doi:10.1038/s41467-022-28724-8
* These authors have contributed equally to this work.

Grifnee, E., Kune, C., Delvaux, C., Quinton, L., Far, J., Mazzucchelli, G., & De Pauw, E. (2022). Label-free higher order structure and dynamic investigation method of proteins in solution using an enzymatic reactor coupled to electrospray high-resolution mass spectrometry. Journal of the American Society for Mass Spectrometry. doi:10.1021/jasms.1c00274

Burat, B.* , Reynaerts, A.* , Baiwir, D., Fleron, M., Eppe, G., Leal, T.* , & Mazzucchelli, G.*. (08 October 2021). Characterization of the Human Eccrine Sweat Proteome—A Focus on the Biological Variability of Individual Sweat Protein Profiles. International Journal of Molecular Sciences, 22 (19). doi:10.3390/ijms221910871
* These authors have contributed equally to this work.

Serteyn, L., Lourme, O., Iannello, L., Baiwir, D., Mazzucchelli, G., Ongena, M., & Francis, F. (06 June 2021). Up-Regulated Salivary Proteins of Brown Marmorated Stink Bug Halyomorpha halys on Plant Growth-Promoting Rhizobacteria-Treated Plants. Journal of Chemical Ecology, 2021 (47), 747-754. doi:10.1007/s10886-021-01293-8

Luis, G.* , Godfroid, A.* , Nishiumi, S., Cimino, J., Blacher, S., Maquoi, E., Wery, C., Collignon, A., Longuespée, R., MONTERORUIZ, L., Dassoul, I., Maloujahmoum, N., Pottier, C., Mazzucchelli, G., De Pauw, E., Bellahcene, A., Yoshida, M., Noël, A., & Sounni, N. E. (2021). Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence. Redox Biology, 43, 102006. doi:10.1016/j.redox.2021.102006
* These authors have contributed equally to this work.

Pierre, N., Baiwir, D., Huynh-Thu, V. A., Mazzucchelli, G., Smargiasso, N., De Pauw, E., Bouhnik, Y., Laharie, D., Colombel, J.-F., Meuwis, M.-A., & Louis, E. (2021). Discovery of biomarker candidates associated with the risk of short-term and mid/long-term relapse after infliximab withdrawal in Crohn's patients: a proteomics-based study. Gut. doi:10.1136/gutjnl-2020-322100

Rapino, F.* , ZHOU, Z.* , RONCERO SANCHEZ, A. M.* , Joiret, M., Seca, C., El Hachem, N., Valenti, G., Latini, S., Shostak, K., Geris, L., Li, P., Huang, G., Mazzucchelli, G., Baiwir, D., Desmet, C., Chariot, A., Georges, M., & Close, P. (2021). Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate. Nature Communications, 12 (1), 2170. doi:10.1038/s41467-021-22254-5
* These authors have contributed equally to this work.

Alevra Sarika, N.* , Payen, V.* , Fleron, M., Ravau, J., Brusa, D., Najimi, M., De Pauw, E., Eppe, G., Mazzucchelli, G., Sokal, E., des Rieux, A., & El Taghdouini, A. (30 May 2020). Human Liver-Derived Extracellular Matrix for the Culture of Distinct Human Primary Liver Cells. Cells, 9(6). doi:10.3390/cells9061357
* These authors have contributed equally to this work.

de Seny, D., Bianchi, E., Baiwir, D., COBRAIVILLE, G., Collin, C., Deliège, M., Kaiser, M.-J., Mazzucchelli, G., Hauzeur, J.-P., Delvenne, P., & Malaise, M. (2020). Proteins involved in the endoplasmic reticulum stress are modulated in synovitis of osteoarthritis, chronic pyrophosphate arthropathy and rheumatoid arthritis, and correlate with the histological inflammatory score. Scientific Reports, 10 (1). doi:10.1038/s41598-020-70803-7

Martinet, L., Naômé, A., Baiwir, D., De Pauw, E., Mazzucchelli, G., & Rigali, S. (2020). On the Risks of Phylogeny-Based Strain Prioritization for Drug Discovery: Streptomyces lunaelactis as a Case Study. Biomolecules, 10 (7). doi:10.3390/biom10071027

Dewez, F., Martin-Lorenzo, M., Herfs, M., Baiwir, D., Mazzucchelli, G., De Pauw, E., Heeren, R. M. A., & Balluff, B. (14 June 2019). Precise co-registration of mass spectrometry imaging, histology, and laser microdissection-based omics. Analytical and Bioanalytical Chemistry, 411, 5647-5653. doi:10.1007/s00216-019-01983-z

Baumans, F., Baiwir, D., Colombo, M., Allain, C., Tavernier, V., Leroy, B., Wattiez, R., De Pauw, E., Eppe, G., & Mazzucchelli, G. (April 2019). New methodology to monitor the oxidation of MET due to LC separation [Poster presentation]. 4th NVMS-BSMS Conference on Mass spectrometry, Kerkrade, Netherlands.

Henrotin, Y., Sanchez, C., De Pauw, E., & Mazzucchelli, G. (30 January 2019). OSTEOMODULIN AND OSTEOMODULIN FRAGMENTS AS BIOMARKERS FOR OSTEOARTHRITIS AND USE THEREOF.

Arsova, B., Amini, S., Scheepers, M., Baiwir, D., Mazzucchelli, G., Carnol, M., Bosman, B., Motte, P., De Pauw, E., Watt, M., & Hanikenne, M. (2019). Resolution of the proteome, transcript and ionome dynamics upon Zn re-supply in Zn-deficient Arabidopsis. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/256956. doi:10.1101/600569

Francis, F., Doyen, V., Debaugnies, F., Mazzucchelli, G., Caparros Megido, R., Alabi, T., Blecker, C., Haubruge, E., & Corazza, F. (2019). Limited cross reactivity among arginine kinase allergens from mealworm and cricket edible insects. Food Chemistry, 276, 714-718. doi:10.1016/j.foodchem.2018.10.082

Pierre, N., Salee, C., MASSOT, C., BLETARD, N., Mazzucchelli, G., Smargiasso, N., Morsa, D., Baiwir, D., De Pauw, E., REENAERS, C., VAN KEMSEKE, C., LOLY, J.-P., Delvenne, P., Meuwis, M.-A., & Louis, E. (2019). Proteomics highlights common and distinct pathophysiological processes associated with ileal and colonic ulcers in Crohn's disease. Journal of Crohn's & colitis. doi:10.1093/ecco-jcc/jjz130

Baumans, F., Baiwir, D. (Other coll.), Allain, C. (Other coll.), Eppe, G. (Other coll.), Tavernier, V. (Other coll.), Leroy, B. (Other coll.), Colombo, M. (Other coll.), De Pauw, E. (Other coll.), Wattiez, R. (Other coll.), & Mazzucchelli, G. (Other coll.). (December 2018). KIT QUANTA - standardization kit for absolute protein quantitation: study of the digestion kinetic of the chimeric protein standard [Poster presentation]. Workshop and Symposium of the Belgian Proteomics Association (BePAc).

Sanchez, C., Mazzucchelli, G., Comblain, F., Lambert, C., De Pauw, E., & Henrotin, Y. (June 2018). Proteomic analysis of osteoblasts secretome provides new insights in mechanisms underlying osteoarthritis subchondral bone sclerosis. Annals of the Rheumatic Diseases, 77 (supplement 2), 894.

Sanchez, C., Mazzucchelli, G., Lambert, C., Comblain, F., De Pauw, E., & Henrotin, Y. (April 2018). Proteomic analysis of osteoblasts secretome provides new insights in mechanisms underlying osteoarthritis subchondral bone sclerosis. Osteoarthritis and Cartilage, 26 (supplement 1), 89. doi:10.1016/j.joca.2018.02.192

Merli, A.-M., MASSOT, C., BLETARD, N., QUESADA-CALVO, F., Baiwir, D., Mazzucchelli, G., Smargiasso, N., Servais, L., Oury, C., De Pauw-Gillet, M.-C., De Pauw, E., COIMBRA MARQUES, C., Colard, A., Vijverman, A., DELVENNE, P., MEUWIS, M.-A., & LOUIS, E. (February 2018). Potential diagnostic biomarkers of Ulcerative colitis-associated colorectal dysplasia [Paper presentation]. 13th congress of European Crohn's and Colitis Organisation, Vienne, Austria.

Pierre, N., REENAERS, C., VAN KEMSEKE, C., LOLY, J.-P., Mazzucchelli, G., Smargiasso, N., Baiwir, D., Morsa, D., De Pauw, E., MEUWIS, M.-A., & Louis, E. (2018). Proteomic analysis highlights divergences and convergences between ileal and colonic pathological processes involved in Crohn’s ulcers. Journal of Crohn's and Colitis. doi:10.1093/ecco-jcc/jjx180.184

Merli, A.-M., MASSOT, C., BLETARD, N., QUESADA-CALVO, F., Baiwir, D., Mazzucchelli, G., Smargiasso, N., Servais, L., Oury, C., De Pauw-Gillet, M.-C., De Pauw, E., COIMBRA MARQUES, C., Colard, A., Vijverman, A., DELVENNE, P., MEUWIS, M.-A., & LOUIS, E. (27 January 2018). Potential diagnostic biomarkers of Ulcerative Colitis-associated colorectal dysplasia [Poster presentation]. Belgian Association for Cancer Research Annual Meeting 2018, Liège, Belgium.

Merli, A.-M., MASSOT, C., BLETARD, N., QUESADA-CALVO, F., Baiwir, D., Mazzucchelli, G., Smargiasso, N., Servais, L., Oury, C., De Pauw-Gillet, M.-C., De Pauw, E., COIMBRA MARQUES, C., Colard, A., Vijverman, A., DELVENNE, P., MEUWIS, M.-A., & LOUIS, E. (2018). Potential diagnostic biomarkers of Ulcerative colitis-associated colorectal dysplasia. Acta Gastro-Enterologica Belgica.

Sanchez, C., Mazzucchelli, G., Lambert, C., Comblain, F., De Pauw, E., & Henrotin, Y. (2018). Comparison of secretome from osteoblasts derived from sclerotic versus non-sclerotic subchondral bone in OA: A pilot study. PLoS ONE, 13 (3), 0194591. doi:10.1371/journal.pone.0194591

Truong, D.-H., Nguyen, H. C., Bauwens, J., Mazzucchelli, G., Lognay, G., & Francis, F. (2018). Plant defense in response to chewing insects: Proteome analysis of Arabidopsis thaliana damaged by Plutella xylostella. Journal of Plant Interactions, 13 (1), 30-36. doi:10.1080/17429145.2017.1414320

Sanchez, C., Mazzucchelli, G., Lambert, C., Comblain, F., De Pauw, E., & Henrotin, Y. (December 2017). L’analyse protéomique du sécrétome des ostéoblastes fournis de nouvelles indications sur les mécanismes de la sclérose sous-chondrale dans l’arthrose. Revue du Rhumatisme, 84 (S1), 295.

Henrotin, Y., Sanchez, C., De Pauw, E., & Mazzucchelli, G. (27 September 2017). Osteomodulin and osteomodulin fragments as biomarkers for osteoarthritis and use thereof.

Henrotin, Y., Sanchez, C., De Pauw, E., & Mazzucchelli, G. (25 September 2017). Osteomodulin and osteomodulin fragments as biomarkers for osteoarthritis and use thereof.

Arsova, B., Amini, S., Scheepers, M., Baiwir, D., Mazzucchelli, G., Carnol, M., Bosman, B., De Pauw, E., Watt, M., & Hanikenne, M. (August 2017). Elucidation of early Zinc sensing and signaling events in Arabidopsis, upon Zinc starvation and re-supply [Poster presentation]. International Plant Nutrition Colloquium.

QUESADA-CALVO, F., MASSOT, C., Bertrand, V., Longuespée, R., BLETARD, N., SOMJA, J., Mazzucchelli, G., Smargiasso, N., Baiwir, D., De Pauw-Gillet, M.-C., Delvenne, P., MALAISE, M., COIMBRA MARQUES, C., POLUS, M., De Pauw, E., MEUWIS, M.-A., & Louis, E. (24 March 2017). OLFM4, KNG1 and Sec24C identified by proteomics and immunohistochemistry as potential markers of early colorectal cancer stages. Clinical Proteomics, 24 (9). doi:10.1186/s12014-017-9143-3

Alberts, D., Longuespée, R., Smargiasso, N., Mazzucchelli, G., Baiwir, D., DELVENNE, P., Pamelard, F., Picard de Meller, G., & De Pauw, E. (09 June 2016). MALDI-imaging guided microproteomics workflow for biomarker discovery of intra-tumor heterogeneity [Poster presentation]. 64th Conference on Mass Spectrometry and Allied Topics, San Antionio, Texas, United States.

Bekhouche, M., Leduc, C., Dupont, L., Janssen, L., Delolme, F., Vadon-Le Goff, S., Smargiasso, N., Baiwir, D., Mazzucchelli, G., Zanella-Cleon, I., Dubail, J., De Pauw, E., Nusgens, B., Hulmes, D., Moali, C., & Colige, A. (06 January 2016). Determination of the substrate repertoire of ADAMTS2, 3 and 14 significantly broadens their functions and identifies extracellular matrix organization and TGF-beta signaling as primary targets. FASEB Journal, 5, 1741-56. doi:10.1096/fj.15-279869

Baiwir, D., Mazzucchelli, G., Smargiasso, N., QUESADA CALVO, F., De Pauw, E., MALAISE, M., Louis, E., & MEUWIS, M.-A. (December 2015). Comparison of serum fractionation methods by data independent label-free proteomics. EuPA Open Proteomics, 9, 14-22. doi:10.1016/j.euprot.2015.07.009

Truong, T. D., Bauwens, J., Delaplace, P., Mazzucchelli, G., Lognay, G., & Francis, F. (2015). Proteomic analysis of Arabidopsis thaliana (L.) Heynh responses to a generalist sucking pest (Myzus persicae Sulzer). Plant Biology, 17 (6), 1210-1217. doi:10.1111/plb.12363

Baiwir, D., Mazzucchelli, G., Smargiasso, N., & De Pauw, E. (06 October 2014). SRM Vs HR-MS quantitative proteomics: matrix effect and LOQ in serum [Poster presentation]. 13th Human Proteome Organization World Congress.

MEUWIS, M.-A., Baiwir, D., Mazzucchelli, G., Smargiasso, N., Quesada-Calvo, F., MALAISE, M., De Pauw, E., The GETAID, & LOUIS, E. (06 October 2014). Potential Proteomic Biomarkers Associated To Mucosal Healing In Crohn’s Disease [Poster presentation]. HUPO2014, Madrid, Spain.

Czerwinska, I., Mazzucchelli, G., Smargiasso, N., Riou, J.-F., De Pauw-Gillet, M.-C., & De Pauw, E. (2014). Development of an approach for analyzing the telomere interacting proteins [Poster presentation]. From analytical to functional proteomics.

Longuespée, R., Fléron, M., Pottier, C., QUESADA CALVO, F., Meuwis, M.-A., Baiwir, D., Smargiasso, N., Mazzucchelli, G., De Pauw-Gillet, M.-C., Delvenne, P., & De Pauw, E. (2014). Tissue Proteomics for the Next Decade? Towards a Molecular Dimension in Histology. OMICS: A Journal of Integrative Biology. doi:10.1089/omi.2014.0033

Smargiasso, N., Mazzucchelli, G., Baiwir, D., LOUIS, E., Quesada-Calvo, F., MEUWIS, M.-A., & De Pauw, E. (2014). Data dependent versus Data independent acquisition applied to samples with different protein dynamic range [Poster presentation]. 13th Human Proteome Organization World Congress.

Giusti, A., Leprince, P., Mazzucchelli, G., Lagadic, L., Ducrot, V., Thomé, J.-P., & Joaquim-Justo, C. (November 2013). Proteomic Analysis of the Reproductive Organs of the Hermaphroditic Gastropod Lymnea stagnalis Exposed to Different Endocrine Disrupting Chemicals. PLoS ONE, 8 (11), 81086. doi:10.1371/journal.pone.0081086

Turtoi, A., Musmeci, D., Naccarato, A. G., Scatena, C., Ortenzi, V., Kiss, R., Murtas, D., Patsos, G., Mazzucchelli, G., De Pauw, E., Bevilacqua, G., & Castronovo, V. (2012). Sparc-like protein 1 is a new marker of human glioma progression. Journal of Proteome Research, 11 (10), 5011-21. doi:10.1021/pr3005698

Far, J., Mazzucchelli, G., De Pauw, E., & Eppe, G. (April 2011). Structural characterization of isobar selenium containing contaminant in a commercially available selenomethionine standard using electrospray – Ion Mobility Time of Flight Mass Spectrometry [Poster presentation]. BSMS.

Kischel, P., Waltregny, D., Greffe, Y., Mazzucchelli, G., De Pauw, E., de Leval, L., & Castronovo, V. (2011). Identification of stromal proteins overexpressed in nodular sclerosis Hodgkin lymphoma. Proteome Science, 9 (1), 63. doi:10.1186/1477-5956-9-63

Piette, F., D'Amico, S., Struvay, C., Mazzucchelli, G., Renaut, J., Tutino, M. L., Danchin, A., Leprince, P., & Feller, G. (2010). Proteomics of life at low temperatures: trigger factor is the primary chaperone in the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125. Molecular Microbiology, 76 (1), 120-132. doi:10.1111/j.1365-2958.2010.07084.x

Rosu, F., Gabelica, V., Smargiasso, N., Mazzucchelli, G., Shin-ya, K., & De Pauw, E. (2010). Cation Involvement in Telomestatin Binding to G-Quadruplex DNA. Journal of Nucleic Acids, 121259. doi:10.4061/2010/121259

Mazzucchelli, G. (2008). Analyse protéomique de l'inhibition de la télomérase par des ligands spécifiques des télomères [Doctoral thesis, Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/315303

Das, K., Siebert, U., Gillet, A., Dupont, A., Di-Poï, C., Fonfara, S., Mazzucchelli, G., De Pauw, E., & De Pauw-Gillet, M.-C. (2008). Mercury immune toxicity in harbour seals: Links to in vitro toxicity. Environmental Health, 7, 52. doi:10.1186/1476-069X-7-52

Harmel, N., Letocart, E., Cherqui, A., Giordanengo, P., Mazzucchelli, G., Guillonneau, F., De Pauw, E., Haubruge, E., & Francis, F. (2008). Identification of aphid salivary proteins: a proteomic investigation of Myzus persicae. Insect Molecular Biology, 17 (2), 165-74. doi:10.1111/j.1365-2583.2008.00790.x

Mazzucchelli, G., Gabelica, V., Smargiasso, N., Fleron, M., Ashimwe, W., Rosu, F., De Pauw-Gillet, M.-C., Riou, J.-F., & De Pauw, E. (2008). Proteome alteration induced by hTERT transfection of human fibroblast cells. Proteome Science, 6 (1), 12. doi:10.1186/1477-5956-6-1

Mazzucchelli, G., Gabelica, V., Smargiasso, N., Rosu, F., De Pauw-Gillet, M.-C., Riou, J.-F., & De Pauw, E. (2008). Proteomic analysis of telomerase inhibition by telomere specific ligands. Anticancer Research, 28 (5c), 3257-3258.

Bettendorff, L., Wirtzfeld, B., Makarchikov, A. F., Mazzucchelli, G., Frederich, M., Gigliobianco, T., Gangolf, M., De Pauw, E., Angenot, L., & Wins, P. (2007). Discovery of a natural thiamine adenine nucleotide. Nature Chemical Biology, 3 (4), 211-212. doi:10.1038/nchembio867

Francis, F., Mazzucchelli, G., De Pauw, E., & Haubruge, E. (2007). Protéomique et entomologie moléculaire : étude des relations plantes – pucerons. In Proceedings Congrès SFEAP.

Francis, F., Gerkens, P., Harmel, N., Mazzucchelli, G., De Pauw, E., & Haubruge, E. (2006). Proteomics in Myzus persicae: effect of aphid host plant switch. Insect Biochemistry and Molecular Biology, 36 (3), 219-27. doi:10.1016/j.ibmb.2006.01.018