Publications and communications of Emmanuel Di Valentin

Colinet, M.* , Chiver, I.* , Bonafina, A., Masset, G., Almansa Amores, D., Di Valentin, E., Twizere, J.-C., Nguyen, L.* , & Espuny Camacho, I. M.*. (2024). SARS-CoV2 infection triggers reactive astrocyte states and inflammatory conditions in long-term Human Cortical Organoids. ORBi-University of Liège.
* These authors have contributed equally to this work.

Bou Malham, V., Benzoubir, N., Vaquero, J., Desterke, C., Agnetti, J., Song, P. X., Gonzalez-Sanchez, E., Arbelaiz, A., Jacques, S., Di Valentin, E., Rahmouni, S., Tan, T. Z., Samuel, D., Thiery, J. P., Sebagh, M., Fouassier, L., & Gassama-Diagne, A. (2023). Intrinsic cancer cell phosphoinositide 3-kinase δ regulates fibrosis and vascular development in cholangiocarcinoma. Liver International. doi:10.1111/liv.15751

BOEMER, F., JOSSE, C., LUIS, G., Di Valentin, E., Thiry, J., CELLO, C., CABERG, J.-H., DADOUMONT, C., HARVENGT, J., Lumaka, A., BOURS, V., & DEBRAY, F.-G. (18 February 2022). Novel Loss of Function Variant in BCKDK Causes a Treatable Developmental and Epileptic Encephalopathy. International Journal of Molecular Sciences, 23 (4), 2253. doi:10.3390/ijms23042253

Agnetti, J.* , Vanessa Bou Malham* , Christophe Desterke* , Nassima Benzoubir, Juan Peng Wang, Sophie Jacques, Rahmouni, S., Di Valentin, E., Tuan Zea Tan, Didier Samuel, Jean Paul Thiery, & Ama Gassama-Diagne. (2022). PI3Kδ activity controls 1 plasticity and discriminates between EMT and stemness based on distinct TGF signalling. Communications Biology, 5, 740. doi:10.1038/s42003-022-03637-w
* These authors have contributed equally to this work.

Jacques, S., Arjomand, A., Perée, H., COLLINS, P., Mayer, A., Lavergne, A., Wéry, M., Mni, M., Hego, A., Thuillier, V., Becker, G., Bahri, M. A., Plenevaux, A., Di Valentin, E., Oury, C., MOUTSCHEN, M., Delvenne, P., Paquot, N., & Rahmouni, S. (2021). Dual‑specificity phosphatase 3 deletion promotes obesity, non‑alcoholic steatohepatitis and hepatocellular carcinoma. Scientific Reports, 11, 5817. doi:10.1038/s41598-021-85089-6

Niemi, M., Gazon, H., JUSZCZAK, D., FADEUR, M., CAMBY, S., MEURIS, C., THYS, M., JACQUES, J., HENKET, M., BEGUIN, Y., Rahmouni, S., Lebrun, M., MOUTSCHEN, M., Misset, B., DARCIS, G., GUIOT, J., AZARZAR, S., DELLOT, P., GOFFLOT, S., ... HUYNEN, P. (Other coll.). (2021). Mapping the human genetic architecture of COVID-19. Nature, 600, 472-477. doi:10.1038/s41586-021-03767-x

Dedobbeleer, M., Willems, E., Lambert, J., LOMBARD, A., Di Gregorio, M., Lumapat, P. N., Di Valentin, E., Freeman, S., Goffart, N., Scholtes, F., & Rogister, B. (2020). MKP1 phosphatase is recruited by CXCL12 in glioblastoma cells and plays a role in DNA strand breaks repair. Carcinogenesis. doi:10.1093/carcin/bgz151

Lombard, A., Di Gregorio, M., COPPIETERS, N., Di Valentin, E., Hego, A., Martin, D., & Rogister, B. (2020). Communicating hydrocephalus associated to ventral leptomeningeal invasion leads to precocious death in a glioblastoma orthotopic xenograft model. Neuro-Oncology Advances.

Rademaker, G., Costanza, B., Anania, S., Agirman, F., Maloujahmoum, N., Di Valentin, E., Goval, J.-J., Bellahcene, A., Castronovo, V., & Peulen, O. (June 2019). Myoferlin contributes to the metastatic phenotype of pancreatic cancer cells by enhancing their migratory capacity through the control of oxidative phosphorylation. Cancers, 11 (6). doi:10.3390/cancers11060853

Fettweis, G., Di Valentin, E., L'homme, L., Lassence, C., Dequiedt, F., Fillet, M., Coupienne, I., & Piette, J. (2017). RIP3 antagonizes a TSC2-mediated pro-survival pathway in glioblastoma cell death. Biochimica et Biophysica Acta. doi:10.1016/j.bbamcr.2016.10.014

Goffart, N., KROONEN, J., Di Valentin, E., Dedobbeleer, M., Denne, A., Martinive, P., & Rogister, B. (2015). Adult mouse subventricular zones stimulate glioblastoma stem cells specific invasion through CXCL12/CXCR4 signaling. Neuro-Oncology, 17 (1), 81-94. doi:10.1093/neuonc/nou144

Maris, P., Blomme, A., Palacios, A. P., Costanza, B., Bellahcene, A., BIANCHI, E., GOFFLOT, S., Drion, P., Trombino, G. E., Di Valentin, E., CUSUMANO, G., MAWEJA, S., JERUSALEM, G., Delvenne, P., LIFRANGE, E., Castronovo, V., & Turtoi, A. (2015). Asporin Is a Fibroblast-Derived TGF-beta1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer. PLoS Medicine, 12 (9), 1001871. doi:10.1371/journal.pmed.1001871

Lebrun, M., Thelen, N., Thiry, M., Riva, L., Ote, I., Condé, C., Vandevenne, P., Di Valentin, E., BONTEMS, S., & Sadzot-Delvaux, C. (2014). Varicella-zoster virus induces the formation of dynamic nuclear capsid aggregates. Virology, 454-455, 311-27. doi:10.1016/j.virol.2014.02.023

Condé, C., Rambout, X., Lebrun, M., Lecat, A., Di Valentin, E., Dequiedt, F., Piette, J., Gloire, G., & Legrand, S. (2012). The inositol phosphatase SHIP-1 inhibits NOD2-induced NF-κB activation by disturbing the interaction of XIAP with RIP2. PLoS ONE. doi:10.1371/journal.pone.0041005

Sabatel, H., Di Valentin, E., Gloire, G., Dequiedt, F., Piette, J., & Habraken, Y. (2012). Phosphorylation of p65(RelA) on Ser547 by ATM represses NF-κB-dependent transcription of specific genes after genotoxic stress. PLoS ONE. doi:10.1371/journal.pone.0038246

Vandevenne, P., Lebrun, M., El Mjiyad, N., Ote, I., Di Valentin, E., Habraken, Y., Dortu, E., Piette, J., & Sadzot-Delvaux, C. (February 2011). The varicella-zoster virus ORF47 kinase interferes with host innate immune response by inhibiting the activation of IRF3. PLoS ONE, 9 (2). doi:10.1371/journal.pone.0016870

Bogaert, P., Naessens, T., De Koker, S., Hennuy, B., Hacha, J., Smet, M., Cataldo, D., Di Valentin, E., Piette, J., Tournoy, K. G., & Grooten, J.-M. (2011). Inflammatory signatures for eosinophilic versus neutrophilic allergic pulmonary inflammation reveal critical regulatory checkpoints. American Journal of Physiology - Lung Cellular and Molecular Physiology, sous presse. doi:10.1152/ajplung.00202.2010

Garbacki, N., Di Valentin, E., Huynh-Thu, V. A., Geurts, P., Irrthum, A., Crahay, C., Arnould, T., Deroanne, C., Piette, J., Cataldo, D., & Colige, A. (2011). MicroRNAs Profiling in Murine Models of Acute and Chronic Asthma: A Relationship with mRNAs Targets. PLoS ONE. doi:10.1371/journal.pone.0016509

Charlier, E., Condé, C., Zhang, J., Deneubourg, L., Di Valentin, E., Rahmouni, S., Chariot, A., Agostinis, P., Pang, P.-C., Haslam, S., Dell, A., Penninger, J., Erneux, C., Piette, J., & Gloire, G. (2010). SHIP-1 inhibits CD95/APO-1/Fas-induced apoptosis in primary T lymphocytes and T leukemic cells by promoting CD95 glycosylation independently of its phosphatase activity. Leukemia. doi:10.1038/leu.2010.9

Habran, L., El Mjiyad, N., Di Valentin, E., Sadzot-Delvaux, C., Bontems, S., & Piette, J. (October 2007). The varicella-zoster virus immediate-early 63 protein affects chromatin-controlled gene transcription in a cell-type dependent manner. BMC Molecular Biology, 8, 99. doi:10.1186/1471-2199-8-99

Sadzot-Delvaux, C., Di Valentin, E., & Bontems, S. (2006). Le virus de la varicelle et du zona : un alphaherpesvirus pas vraiment comme les autres. Virologie, 10 (3), 219-232.

Habran, L., Bontems, S., Di Valentin, E., Sadzot-Delvaux, C., & Piette, J. (2005). Varicella-zoster virus IE63 protein phosphorylation by roscovitine-sensitive cyclin-dependent kinases modulates its cellular localization and activity. Journal of Biological Chemistry, 280 (32), 29135-43. doi:10.1074/jbc.M503312200

Bontems, S., Di Valentin, E., Baudoux, L., Rentier, B., Sadzot-Delvaux, C., & Piette, J. (07 June 2002). Phosphorylation of varicella-zoster virus IE63 protein by casein kinases influences its cellular localization and gene regulation activity. Journal of Biological Chemistry, 277 (23), 21050-21060. doi:10.1074/jbc.M111872200