Martinet, L., Naômé, A., Rezende, L. C. D., Tellatin, D., Pignon, B., Docquier, J.-D., Sannio, F., Baiwir, D., Mazzucchelli, G., Frederich, M., & Rigali, S. (06 January 2023). Lunaemycins, New Cyclic Hexapeptide Antibiotics from the Cave Moonmilk-Dweller Streptomyces lunaelactis MM109T. International Journal of Molecular Sciences, 24 (2), 1114. doi:10.3390/ijms24021114 |
Sannio, F., Brizzi, A., Del Prete, R., Avigliano, M., Simone, T., Pagli, C., Ferraro, T., De Luca, F., Paolino, M., Corelli, F., Mugnaini, C., & Docquier, J.-D. (16 December 2022). Optimization of Pyrazole Compounds as Antibiotic Adjuvants Active against Colistin- and Carbapenem-Resistant Acinetobacter baumannii. Antibiotics, 11 (12), 1832. doi:10.3390/antibiotics11121832 |
Legru, A.* , Verdirosa, F.* , Vo-Hoang, Y., Tassone, G., Vascon, F., Thomas, C. A., Sannio, F., Corsica, G., Benvenuti, M., Feller, G., Coulon, R., Marcoccia, F., Devente, S. R., Bouajila, E., Piveteau, C., Leroux, F., Deprez-Poulain, R., Deprez, B., Licznar-Fajardo, P., ... Gavara, L.*. (30 November 2022). Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates. Journal of Medicinal Chemistry, 65, 16392-16419. doi:10.1021/acs.jmedchem.2c01257 * These authors have contributed equally to this work. |
Legru, A., Gavara L., Verdirosa F., Vo-Hoang Y., Tassone G., Corsica G., Vascone F., Thomas C., Feller, G., Crowder M., Cendron L., Pozzi C., Mangani S., Docquier, J.-D., & Hernandez J.-F. (04 September 2022). 1,2,4-TRIAZOLE-3-THIONE COMPOUNDS POTENTLY INHIBIT VIM AND NDM-1 METALLO-b-LACTAMASES AND RE-SENSITIZE MULTI-RESISTANT CLINICAL ISOLATES TO MEROPENEM [Poster presentation]. International Symposium on Medicinal Chemistry, Nice, France. |
Gavara, L., Verdirosa, F., Sevaille, L., Legru, A., Corsica, G., Nauton, L., Mercuri, P., Sannio, F., De Luca, F., Hadjadj, M., Cerboni, G., Vo Hoang, Y., Licznar-Fajardo, P., Galleni, M., Docquier, J.-D., & Hernandez, J.-F. (11 August 2022). 1,2,4-Triazole-3-thione analogues with an arylakyl group at position 4 as metallo-β-lactamase inhibitors. Bioorganic and Medicinal Chemistry, 72, 116964. doi:10.1016/j.bmc.2022.116964 |
Papp-Wallace, K. M., Docquier, J.-D., Kerff, F., & Power, P. (2022). Editorial: Structural and Biochemical Aspects of the Interaction of β-Lactamases With State-of-the-Art Inhibitors. Frontiers in Microbiology, 13, 849324. doi:10.3389/fmicb.2022.849324 |
Terrosi, C., Anichini, G., Docquier, J.-D., Gori Savellini, G., Gandolfo, C., Pavone, F. S., & Cusi, M. G. (08 December 2021). Efficient Inactivation of SARS-CoV-2 and Other RNA or DNA Viruses with Blue LED Light. Pathogens (Basel, Switzerland), 10 (12), 1590. doi:10.3390/pathogens10121590 |
Piccirilli, A., Brisdelli, F., Docquier, J.-D., Aschi, M., Cherubini, S., De Luca, F., Matagne, A., Amicosante, G., & Perilli, M. (2020). Amino acid replacement at position 228 induces fluctuation in the Ω-loop of KPC-3 and reduces the affinity against oxyimino cephalosporins: Kinetic and molecular dynamics studies. Catalysts, 10 (12), 1-14. doi:10.3390/catal10121474 |
Sevaille, L., Gavara, L., Bebrone, C., De Luca, F., Nauton, L., Achard, M., Mercuri, P., Tanfoni, S., Borgianni, L., Guyon, C., Lonjon, P., Turan-Zitouni, G., Dzieciolowski, J., Becker, K., Bénard, L., Condon, C., Maillard, L., Martinez, J., Frère, J.-M., ... Hernandez, J.-F. (2017). 1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases. ChemMedChem, 12, 972-985. doi:10.1002/cmdc.201700186 |
Lassaux, P., Traoré, D., Loisel, E., Favier, A., Docquier, J.-D., Sohier, J., Laurent, C., Bebrone, C., Frère, J.-M., Ferrer, J.-L., & Galleni, M. (2011). Biochemical and structural characterization of the subclass B1 metallo-β-lactamase VIM-4. Antimicrobial Agents and Chemotherapy. doi:10.1128/AAC.01486-09 |
MEEX, C., MELIN, P., Docquier, J.-D., Kabasele, T., HUYNEN, P., Tulkens, P., Giet, D., & De Mol, P. (2008). Presenec of extended-spectrum beta-lactamase-producing Enterobacteriaceae in the fecal flora of patients from general practice. In ECCMID (Ed.), Program and Abstracts book of the 18th ECCMID. |
Michaux, C., Massant, J., Kerff, F., Frère, J.-M., Docquier, J.-D., Vandenberghe, I., Samyn, B., Pierrard, A., Feller, G., Charlier, P., Van Beeumen, J., & Wouters, J. (2008). Crystal structure of a cold-adapted class C beta-lactamase. FEBS Journal, 275 (8), 1687-97. doi:10.1111/j.1742-4658.2008.06324.x |
Cornaglia, G., Akova, M., Amicosante, G., Canton, R., Cauda, R., Docquier, J.-D., Edelstein, M., Frère, J.-M., Fuzi, M., Galleni, M., Giamarellou, H., Gniadkowski, M., Koncan, R., Libisch, B., Luzzaro, F., Miriagou, V., Navarro, F., Nordmann, P., Pagani, L., ... Rossolini, G. M. (April 2007). Metallo-beta-lactamases as emerging resistance determinants in Gram-negative pathogens: open issues. International Journal of Antimicrobial Agents, 29 (4), 380-388. doi:10.1016/j.ijantimicag.2006.10.008 |
Bebrone, C., Moali, C., Mahy, F., Rival, S., Docquier, J.-D., Rossolini, G. M., Fastrez, J., Pratt, R. F., Frère, J.-M., & Galleni, M. (June 2001). Centa as a Chromogenic Substrate for Studying Beta-Lactamases. Antimicrobial Agents and Chemotherapy, 45 (6), 1868-71. doi:10.1128/AAC.45.6.1868-1871.2001 |