Lebrun, P., Boulanger, B., Debrus, B., Lambert, P., & Hubert, P. (2013). A Bayesian Design Space for analytical methods based on multivariate models and predictions. Journal of Biopharmaceutical Statistics, 23, 1330–1351. doi:10.1080/10543406.2013.834922 |
Mbinze Kindenge, J., Lebrun, P., Debrus, B., Dispas, A., Hubert, C., Rozet, E., Marini Djang'Eing'A, R., & Hubert, P. (June 2012). APPLICATION OF AN INNOVATIVE DESIGN SPACE OPTIMIZATION STRATEGY TO THE DEVELOPMENT OF LC METHODS TO COMBAT POTENTIALLY COUNTERFEIT NSAIDS [Poster presentation]. HPLC 2012, Anaheim, California, United States. |
Mbinze Kindenge, J., Lebrun, P., Debrus, B., Dispas, A., Hubert, P., & Marini Djang'Eing'A, R. (May 2012). THE DEVELOPMENT OF LC GENERIC ANALYTICAL METHODS TO FIGHT COUNTERFEIT NSAIDS USING DESIGN SPACE OPTIMISATION STRATEGY [Paper presentation]. 16ème FORUM DES SCIENCES PHARMACEUTIQUES, Blankenberge, Belgium. |
Rozet, E., Debrus, B., Lebrun, P., Boulanger, B., & Hubert, P. (February 2012). COMBINATION OF INDEPENDENT COMPONENT ANALYSIS, DESIGN OF EXPERIMENTS AND DESIGN SPACE FOR A NOVEL METHODOLOGY TO DEVELOP CHROMATOGRAPHIC METHODS [Poster presentation]. 12th International Symposium on Hyphenated Techniques for Chromatography (HTC-12), Bruges, Belgium. |
Tyteca, E., Liekens, A., Clicq, D., Fanigliulo, A., Debrus, B., Rudaz, S., Guillarme, D., & Desmet, G. (2012). Predictive elution window stretching and shifting as a generic search strategy for automated method development for liquid chromatography. Analytical Chemistry, 84 (18), 7823-7830. doi:10.1021/ac301331g |
Dispas, A., Lebrun, P., Mbinze Kindenge, J., Debrus, B., Mavar Tayer Mbay, J., Boulanger, B., Marini Djang'Eing'A, R., & Hubert, P. (December 2011). Application d'une nouvelle méthode de développement de méthodes chromatographiques pour lutter contre la contrefaçon des médicaments anti-inflammatoires [Paper presentation]. Chimiométrie 2011, Marseille, France. |
Rozet, E., Debrus, B., Lebrun, P., Boulanger, B., & Hubert, P. (08 September 2011). New Methodology for the Development of Chromatographic Methods [Paper presentation]. 17th International Symposium on Separation Sciences – ISSS 2011, Cluj, Romania. |
Marini Djang'Eing'A, R., Mbinze Kindenge, J., Debrus, B., Lebrun, P., Mantanus, J., Ziemons, E., Lamalle, C., Fillet, M., Rudaz, S., & Hubert, P. (September 2011). IMPLEMENTATION OF GENERIC ANALYTICAL METHODS TO FIGHT AGAINST COUNTERFEIT MEDICINES [Paper presentation]. Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy. |
Debrus, B. (2011). Nouvelle méthodologie pour le développement de méthodes chromatographiques [Doctoral thesis, Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/315366 |
Lebrun, P., Lambert, P., Debrus, B., Hubert, P., Marini Djang'Eing'A, R., Moonen, F., & Boulanger, B. (December 2010). Developing and optimizing analytical chromatographic method in a Quality by Design environment. Bayesian multi-criteria risk-based Design Space to guarantee future quality [Poster presentation]. Chimiométrie 2010, Paris, France. |
Krier, F., Brion, M., Debrus, B., Lebrun, P., Driesen, A., Ziemons, E., Evrard, B., & Hubert, P. (15 November 2010). Optimisation and validation of a fast HPLC method for the quantification of sulindac and its related impurities [Poster presentation]. The FIP Pharmaceutical Sciences World Congress 2010 in association with the AAPS Annual Meeting & Exposition, new orléans, United States. |
Dubois, N., Debrus, B., Hubert, P., & Charlier, C. (September 2010). Validated quantitative simultaneous determination of cocaine, opiates and amphetamines in serum by UHPLC-MS/MS [Poster presentation]. Drug Analysis 2010, Antwerp, Belgium. |
Nistor, I., Debrus, B., Lebrun, P., Lecomte, F., Cao, M., Frederich, M., Angenot, L., Boulanger, B., Oprean, R., & Hubert, P. (September 2010). Application of experimental design and design for the separation of compounds extracted from the leaves of Strychnos Usambarensis [Poster presentation]. Drug analysis 2010, Antwerpen, Belgium. |
Nistor, I., Lecomte, F., Mbinze Kindenge, J., Debrus, B., Lebrun, P., Marini Djang'Eing'A, R., Oprean, R., & Hubert, P. (September 2010). Transfer of a conventional LC method for the screening of conterfeit antimalarial medicines to UHPLC [Poster presentation]. Drug analysis 2010, Antwerpen, Belgium. |
Rafamantanana, M. H., Debrus, B., Raoelison, G. E., Uverg-Ratsimamanga, S., Hubert, P., & Quetin-Leclercq, J. (September 2010). Application of experimental design for the HPLC-UV-MS separation of aporphine alkaloids from leaves of Spirospermum Penduliflorum thouars [Poster presentation]. Drug Analysis 2010, Antwerp, Belgium. |
Nistor, I., Debrus, B., Lebrun, P., Lecomte, F., Martine, C., Frederich, M., Angenot, L., Boulanger, B., Oprean, R., & Hubert, P. (26 January 2010). Optimisation de la séparation des alcaloïdes extraits des feuilles de Strychnos usambarensis au moyen du design space [Paper presentation]. Assemblée générale du CIRM et forum des jeunes chercheurs, Liège, Belgium. |
Dubois, N., Debrus, B., Hubert, P., & Charlier, C. (2010). Validated quantitative simultaneous determination of cocaine opiates and amphetamines in serum by U-HPLC coupled to tandem mass spectrometry. Acta Clinica Belgica, 65 (1), 75-84. doi:10.1179/acb.2010.113 |
Mbinze Kindenge, J., Marini Djang'Eing'A, R., Debrus, B., Lebrun, P., Lecomte, F., Boulanger, B., & Hubert, P. (December 2009). Développement d’une méthode pour la séparation de 19 antipaludéens par HPLC au moyen de la planification expérimentale et du Design Space [Poster presentation]. 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages (SEP'09), Marseille, France. |
Nistor, I., Debrus, B., Lebrun, P., Lecomte, F., Cao, M., Frederich, M., Angenot, L., Boulanger, B., Oprean, R., & Hubert, P. (December 2009). Application de la planification expérimentale et du design space pour la séparation des composés extraits des feuilles de Strychnos usambarensis [Poster presentation]. 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages (SEP'09), Marseille, France. |
Debrus, B., Broséus, J., Guillarme, D., Hubert, P., Veuthey, J.-L., Esseiva, P., & Rudaz, S. (October 2009). Implementation of new Fast-GC-MS and UHPLC-MS/MS data in a conventional GC-MS database for heroin profiling [Paper presentation]. 4èmes journées internationales de toxicologie hospitalière, Liège, Belgium. |
De Backer, B., Debrus, B., Lebrun, P., Dubois, N., Hubert, P., & Charlier, C. (August 2009). Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoïds in cannabis plant material [Poster presentation]. 47ème meeting de l'International Association of Forensic Toxicologists (TIAFT), Genève, Switzerland. |
Debrus, B., Broséus, J., Guillarme, D., Hubert, P., Veuthey, J.-L., Esseiva, P., & Rudaz, S. (August 2009). Transfer of heroin profiling method from conventional GC-MS to Fast-GC-MS and UHPLC-MS/MS [Paper presentation]. TIAFT 2009, Genève, Switzerland. |
Nistor, I., Debrus, B., Lebrun, P., Rozet, E., Ceccato, A., Caliaro, G., Oprean, R., Boulanger, B., & Hubert, P. (27 April 2009). Nouvelle méthodologie pour le développement automatisé de méthodes analytiques en chromatographie liquide pour l'analyse de mélanges de composés inconnus [Paper presentation]. Assemblée générale du CIRM et forum des jeunes chercheurs, Liège, Belgium. |
Debrus, B., Lebrun, P., Rozet, E., Nistor, I., Ceccato, A., Caliaro, G., Oprean, R., Boulanger, B., & Hubert, P. (2009). Nouvelle méthodologie pour le développement automatisé de méthodes analytiques en chromatographie liquide pour l’analyse de mélanges de composés inconnus. Spectra Analyse, 268, 28-33. |
Debrus, B., Lebrun, P., Ceccato, A., Caliaro, G., Rozet, E., Rupérez, J., Barbas, C., Boulanger, B., & Hubert, P. (July 2008). Chromatographic separation of a pharmaceutical formulation using Design of Experiment and Design Space [Poster presentation]. 11th conference on Chemometrics in Analytical Chemistry (CAC'2008), Montpellier, France. |
Debrus, B., Lebrun, P., Ceccato, A., Caliaro, G., Jupérez, J., Barbas, C., Boulanger, B., & Hubert, P. (June 2008). Usefulness of design space for the optimization of chromatographic separations [Paper presentation]. 19th International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2008), Gdansk, Poland. |
Lebrun, P., Debrus, B., Boulanger, B., Caliaro, G., Ceccato, A., & Hubert, P. (June 2007). Numerical separation in HPLC-UV-DAD with Independent Component Analysis (ICA) using high order statistics for the automated identification of peaks [Poster presentation]. HPLC 2007, Gent, Belgium. |
Debrus, B., Lebrun, P., Boulanger, B., Dewé, W., Ceccato, A., & Hubert, P. (20 March 2007). Séparation numérique et quantification automatique de pics en CLHP-UV grâce à l’utilisation de l’analyse en composantes indépendantes (ICA) [Paper presentation]. SEP 2007, Grenoble, France. |
Debrus, B., Lebrun, P., Boulanger, B., Dewé, W., Ceccato, A., & Hubert, P. (20 March 2007). Evaluation d'une nouvelle méthode pour le développement entièrement automatisé de méthodes analytiques en chromatographie liquide [Poster presentation]. SEP 2007, Grenoble, France. |
Boulanger, B., Dewé, W., Ceccato, A., Debrus, B., Lebrun, P., & Hubert, P. (December 2006). Utilisation de l’Analyse en Composantes Indépendantes (ICA) pour la séparation numérique des pics et la quantification automatique en CLHP-UV [Paper presentation]. Chimiométrie 2006, Paris, France. |
Lebrun, P., Boulanger, B., Hubert, P., Debrus, B., & Govaerts, B. (December 2006). Statistical Models and Multi-Criteria Optimization Techniques in Chromatography [Paper presentation]. Chimiométrie 2006, Paris, France. |