Publications and communications of Jacques Crommen

Gou, M.-J., Charpentier, J., Cobraiville, G., Crommen, J., Caers, J., & Fillet, M. (October 2023). Improvement of untargeted proteomics workflow for surfaceome profiling and its evaluation through the implementation of quality controls: Application to multiple myeloma. Analytica Chimica Acta, 1279, 341764. doi:10.1016/j.aca.2023.341764

Ghassemi, M., Demelenne, A., Crommen, J., Servais, A.-C., & Fillet, M. (01 February 2023). Application of cyclodextrins in capillary electrophoresis to improve stereo- and chemo selectivity of phosphorothioate oligonucleotides [Poster presentation]. CIRM Day, Liege, Belgium.

Laurent, A.* , Nix, C.* , Cobraiville, G., Crommen, J., & Fillet, M. (2023). A targeted UHPLC-MS/MS method to monitor lipidomic changes during a physical effort: Optimization and application to blood microsamples from athletes. Journal of Pharmaceutical and Biomedical Analysis, 229, 115373. doi:10.1016/j.jpba.2023.115373

Gou, M.-J., Köse, M. C., Crommen, J., Nix, C., Cobraiville, G., Caers, J., & Fillet, M. (01 November 2022). Contribution of Capillary Zone Electrophoresis Hyphenated with Drift Tube Ion Mobility Mass Spectrometry as a Complementary Tool to Microfluidic Reversed Phase Liquid Chromatography for Antigen Discovery. International Journal of Molecular Sciences, 23 (21), 13350. doi:10.3390/ijms232113350

Nix, C.* , Ghassemi, M.* , Crommen, J., & Fillet, M. (October 2022). Overview on microfluidics devices for monitoring brain disorder biomarkers. TrAC: Trends in Analytical Chemistry, 155, 116693. doi:10.1016/j.trac.2022.116693

Lu, L., Liu, X., Zuo, C., Zhou, J., Zhu, C., Zhang, Z., Fillet, M., Crommen, J., Jiang, Z., & Wang, Q. (08 September 2022). In vitro/in vivo degradation analysis of trastuzumab by combining specific capture on HER2 mimotope peptide modified material and LC-QTOF-MS. Analytica Chimica Acta, 1225, 340199. doi:10.1016/j.aca.2022.340199

Ghassemi K, M., Demelenne, A., Crommen, J., Servais, A.-C., & Fillet, M. (02 August 2022). Improvement of chemo- and stereoselectivity for phosphorothioate oligonucleotides in capillary electrophoresis by addition of cyclodextrins. Journal of Chromatography. A, 1676, 463270. doi:10.1016/j.chroma.2022.463270

Demelenne, A., Ben Yahia, A., Ghassemi, L., Lempereur Delphine, Crommen, J., Servais, A.-C., & Fillet, M. (03 July 2022). Biosimilar comparability of a monoclonal antibody and a FC-Fusion protein by SEC, CGE and RPLC [Poster presentation]. 38th International Symposium on Microscale Separations and Bioanalysis (MSB 2022), Liege, Belgium.

Demelenne, A., Nys, G., Nix, C., Fjeldsted, J. C., Crommen, J., & Fillet, M. (25 January 2022). Separation of phosphorothioated oligonucleotide diastereomers using multiplexed drift tube ion mobility mass spectrometry. Analytica Chimica Acta, 1191, 339297. doi:10.1016/j.aca.2021.339297

Demelenne, A., Servais, A.-C., Crommen, J., & Fillet, M. (16 August 2021). Analytical techniques currently used in the pharmaceutical industry for the quality control of RNA-based therapeutics and ongoing developments. Journal of Chromatography. A, 1651, 462283. doi:10.1016/j.chroma.2021.462283

Demelenne, A., Ben Yahia, A., Lempereur, D., Crommen, J., Servais, A.-C., Fradi, I., & Fillet, M. (2021). Comparison of Three Complementary Analytical Techniques for the Evaluation of the Biosimilar Comparability of a Monoclonal Antibody and an Fc-Fusion Protein. Frontiers in Chemistry, 9, 782099. doi:10.3389/fchem.2021.782099

Yazdani, R., Shams-Bakhsh, M., Hassani-Mehraban, A., Arab, S. S., Thelen, N., Thiry, M., Crommen, J., Fillet, M., Jacobs, N., Brans, A., & Servais, A.-C. (September 2020). Characterization of virus-like particles of grapevine fanleaf virus presenting L2 epitope of human papillomavirus minor capsid protein [Poster presentation]. 36th International Symposium on Microscale Separations and Bioanalysis (e-MSB 2020).

Hemmati, M., Nix, C., Crommen, J., Servais, A.-C., & Fillet, M. (June 2020). Benefits of microsampling and microextraction for metabolomics studies. TrAC: Trends in Analytical Chemistry, 127, 115899. doi:10.1016/j.trac.2020.115899

Demelenne, A., Gou, M.-J., Nys, G., Parulski, C., Crommen, J., Servais, A.-C., & Fillet, M. (2020). Evaluation of Hydrophilic Interaction Liquid Chromatography, Capillary Zone Electrophoresis and Drift Tube Ion-Mobility Quadrupole Time Of Flight mass spectrometry for the characterization of phosphodiester and phosphorothioate oligonucleotides. Journal of Chromatography. A. doi:10.1016/j.chroma.2019.460716

Demelenne, A., NAPP, A., Bouillenne, F., Crommen, J., Servais, A.-C., & Fillet, M. (2019). Insulin aggregation assessment by capillary gel electrophoresis without sodium dodecyl sulfate: Comparison with size-exclusion chromatography. Talanta, 199, 457-463. doi:10.1016/j.talanta.2019.02.074

Huang, Y., Jansen, O., Frederich, M., Mouithys-Mickalad, A., Nys, G., Servais, A.-C., Crommen, J., Jiang, Z., & Fillet, M. (2019). Capillary electrophoresis, high-performance liquid chromatography, and thin-layer chromatography analyses of phenolic compounds from rapeseed plants and evaluation of their antioxidant activity. Journal of Separation Science, 1-10. doi:10.1002/jssc.201800712

Huang, Y., Wang, T., Fillet, M., Crommen, J., & Jiang, Z. (2019). Simultaneous determination of amino acids in different teas using supercritical fluid chromatography coupled with single quadrupole mass spectrometry. Journal of Pharmaceutical Analysis, 9, 254-258. doi:10.1016/j.jpha.2019.05.001

Ion, V., Nys, G., COBRAIVILLE, G., Cavalier, E., Crommen, J., Servais, A.-C., Muntean, D.-L., & Fillet, M. (2019). Ultra-high-performance liquid chromatography-mass spectrometry method for neutrophil gelatinase-associated lipocalin as a predictive biomarker in acute kidney injury. Talanta, 195, 668-675. doi:10.1016/j.talanta.2018.11.050

Moldovan, R.-C., Bodoki, E., Servais, A.-C., Crommen, J., Oprean, R., & Fillet, M. (2019). Selectivity evaluation of phenyl based stationary phases for the analysis of amino acid diastereomers by liquid chromatography coupled with mass spectrometry. Journal of Chromatography. A. doi:10.1016/j.chroma.2018.12.068

Yazdani, R., Shams-Bakhsh, M., Hassani-Mehraban, A., Arab, S. S., Thelen, N., Thiry, M., Crommen, J., Fillet, M., Jacobs, N., Brans, A., & Servais, A.-C. (2019). Production and characterization of virus-like particles of grapevine fanleaf virus presenting L2 epitope of human papillomavirus minor capsid protein. BMC Biotechnology, 19 (1), 81. doi:10.1186/s12896-019-0566-y

Yazdani, R., Shams-Bakhsh, M., Hassani-Mehraban, A., Shahriar Arab, S., Thelen, N., Thiry, M., Crommen, J., Fillet, M., Jacobs, N., Brans, A., & Servais, A.-C. (2019). Characterization of plant virus-based virus-like particles displaying human papillomavirus L2 epitope [Paper presentation]. 3rd International Symposium on Advances in Pharmaceutical Analysis (APA 2019), Xian, China.

Farcas, E., Servais, A.-C., Crommen, J., Pochet, L., & Fillet, M. (July 2018). Electrodriven methodologies for the screening of new antithrombotic drugs [Paper presentation]. 2nd International Symposium on Advances in Pharmaceutical Analysis (APA 2018), Lille, France.

Huang, Y., Tang, G., Zhang, T., Fillet, M., Crommen, J., & Jiang, Z. (2018). Supercritical Fluid Chromatography in Traditional Chinese Medicine Analysis. Journal of Pharmaceutical and Biomedical Analysis, 147, 65-80. doi:10.1016/j.jpba.2017.08.021

Moldovan, R.-C., Bodoki, E., Servais, A.-C., Chankvetadze, B., Crommen, J., Oprean, R., & Fillet, M. (2018). Capillary electrophoresis-mass spectrometry of derivatized amino acids for targeted neurometabolomics – pH mediated reversal of diastereomer migration order. Journal of Chromatography. A, 1564, 199-206. doi:10.1016/j.chroma.2018.06.030

Napp, A., Houbart, V., Demelenne, A., Merville, M.-P., Crommen, J., Dumoulin, M., Garraux, G., Servais, A.-C., & Fillet, M. (2018). Separation and determination of alpha-synuclein monomeric and oligomeric species using two electrophoretic approaches. Electrophoresis, 39 (23), 3022-3031. doi:10.1002/elps.201800224

Tang, G., Huang, Y., Zhang, T., Wang, Q., Crommen, J., Fillet, M., & Jiang, Z. (2018). Determination of phenolic acids in extra virgin olive oil using supercritical fluid chromatography coupled with single quadrupole mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 157, 217-225. doi:10.1016/j.jpba.2018.05.025

Farcas, E., Servais, A.-C., Bouckaert, C., Crommen, J., Pochet, L., & Fillet, M. (13 September 2017). Partial filling affinity capillary electrophoresis as a useful tool for fragment-based drug discovery: A proof of concept on thrombin [Paper presentation]. EDT PhD day, Spa, Belgium.

Huang, Y., Fillet, M., Crommen, J., & Jiang, Z. (02 July 2017). Simultaneous Determination of Free Amino Acid Content in Different Teas using Supercritical Fluid Chromatography Coupled with Single Quadrupole Mass Spectrometry [Poster presentation]. 28th International Symposium on Pharmaceutical and Biomedical Analysis, Madrid, Spain.

Crommen, J., Moldovan, R.-C., Bodoki, E., Servais, A.-C., Oprean, R., & Fillet, M. (July 2017). Fully automated MEKC-MS method with in-capillary derivatization for the chiral analysis of amino acids [Paper presentation]. 28th International Symposium on Pharmaceutical and Biomedical Analysis, Madrid, Spain.

Farcas, E., Bouckaert, C., Servais, A.-C., Crommen, J., Pochet, L., & Fillet, M. (20 June 2017). Optimization of an electrophoretic approach for the screening and the development of new antithrombotic drugs [Paper presentation]. The 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC), Prague, Czechia.

Farcas, E., Bouckaert, C., Servais, A.-C., Crommen, J., Pochet, L., & Fillet, M. (19 June 2017). Optimiaztion of an electrophoretic approach for the screening and the development of new antithrombotic drugs [Poster presentation]. The 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC), Prague, Czechia.

Huang, Y., Jiang, Z., Fillet, M., & Crommen, J. (18 June 2017). DEVELOPMENT AND VALIDATION OF A FAST SFC METHOD FOR THE ANALYSIS OF FLAVONOIDS IN PLANT EXTRACTS [Poster presentation]. HPLC 2017- 45th International Symposium on High Performance Liquid Separations and Related Techniques, Prague, Czechia.

Moldovan, R.-C., Bodoki, E., Servais, A.-C., Crommen, J., Oprean, R., & Fillet, M. (June 2017). Separation of FLEC diastereomers by CE vs. LC approaches in the context of neurometabolomics [Poster presentation]. 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Prague, Czechia.

Farcas, E., Pochet, L., Crommen, J., Servais, A.-C., & Fillet, M. (2017). Capillary electrophoresis in the context of drug discovery. Journal of Pharmaceutical and Biomedical Analysis. doi:10.1016/j.jpba.2017.02.022

Huang, Y., Feng, Y., Tang, G., Li, M., Zhang, T., Fillet, M., Crommen, J., & Jiang, Z. (2017). Development and validation of a fast SFC method for the analysis of flavonoids in plant extracts. Journal of Pharmaceutical and Biomedical Analysis, 140, 384-391. doi:10.1016/j.jpba.2017.03.012

Huang, Y., Zhang, T., Zhao, Y., Zhou, H., Tang, G., Fillet, M., Crommen, J., & Jiang, Z. (2017). Simultaneous analysis of nucleobases, nucleosides and ginsenosides in ginseng extracts using supercritical fluid chromatography coupled with single quadrupole mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 144, 213-219. doi:10.1016/j.jpba.2017.03.059

Moldovan, R.-C., Bodoki, E., Servais, A.-C., Crommen, J., Oprean, R., & Fillet, M. (2017). (+) or (-)-1-(9-fluorenyl)ethyl chloroformate as chiral derivatizing agent: A review. Journal of Chromatography. A, 1513, 1-17. doi:10.1016/j.chroma.2017.07.045

Huang, Y., Fillet, M., Zhang, T., Crommen, J., & Jiang, Z. (13 November 2016). Determination of saccharides in honey using supercritical fluid chromatography coupled with single quadrupole mass spectrometry [Poster presentation]. 27th International Symposium on Pharmaceutical and Biomedical Analysis.

Lamalle, C., Servais, A.-C., Demelenne, A., Crommen, J., & Fillet, M. (2016). Analysis of protamine peptides in insulin pharmaceutical formulations by capillary electrophoresis. Journal of Separation Science, 39 (6), 1189-94. doi:10.1002/jssc.201501093

Moldovan, R.-C., Bodoki, E., Kacso, T., Servais, A.-C., Crommen, J., Oprean, R., & Fillet, M. (2016). A micellar electrokinetic chromatography–mass spectrometry approach using in-capillary diastereomeric derivatization for fully automatized chiral analysis of amino acids. Journal of Chromatography. A. doi:10.1016/j.chroma.2016.08.035

Prior, A., Moldovan, R.-C., Crommen, J., Servais, A.-C., Fillet, M., de Jong, G. J., & Somsen, G. W. (2016). Enantioselective capillary electrophoresis-mass spectrometry of amino acids in cerebrospinal fluid using a chiral derivatizing agent and volatile surfactant. Analytica Chimica Acta, 940, 150-8. doi:10.1016/j.aca.2016.08.040

Servais, A.-C., Janicot, B., Takam, A., Crommen, J., & Fillet, M. (2016). Liquid chromatography separation of the chiral prodrug eslicarbazepine acetate and its main metabolites in polar organic mode. Application to their analysis after in vitro metabolism. Journal of Chromatography. A, 1467, 306-311. doi:10.1016/j.chroma.2016.07.022

Houbart, V., COBRAIVILLE, G., Crommen, J., Servais, A.-C., & Fillet, M. (13 October 2015). Peptide biomarker quantitation from small volume of blood [Paper presentation]. In the framework of High-end Foreign Experts program, Guangzhou, China.

Houbart, V., COBRAIVILLE, G., Crommen, J., Servais, A.-C., & Fillet, M. (July 2015). Analytical strategies for sensitive peptide quantitation from low blood sample volumes [Paper presentation]. 26th International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2015), Tbilisi, Georgia.

Moldovan, R.-C., Kacso, T., Servais, A.-C., Crommen, J., Oprean, R., & Fillet, M. (01 July 2015). D and L amino acid profiling using in-line derivatization and MEKC-ESI-MS [Poster presentation]. 21st International Symposium on Separation Science, Ljubljana, Slovenia.

Crommen, J., Lamalle, C., Servais, A.-C., & Fillet, M. (2015). Separation and determination of insulins and analogs by micellar electrokinetic chromatography [Paper presentation]. 26th International Symposium on Pharmaceutical and Biomedical Analysis (PBA), Tbilisi, Georgia.

Feng, Y., Wang, T., Jiang, Z., Chankvetadze, B., & Crommen, J. (2015). Comparative enantiomer affinity pattern of beta-blockers in aqueous and nonaqueous CE using single-component anionic cyclodextrins. Electrophoresis, 36 (11-12), 1358-64. doi:10.1002/elps.201400462

Lamalle, C., Roland, D., Crommen, J., Servais, A.-C., & Fillet, M. (2015). Separation of human, bovine, and porcine insulins, three very closely related proteins, by micellar electrokinetic chromatography. Electrophoresis, 36 (19), 2504-6. doi:10.1002/elps.201500178

Lamalle, C., Servais, A.-C., RADERMECKER, R., Crommen, J., & Fillet, M. (2015). Simultaneous determination of insulin and its analogues in pharmaceutical formulations by micellar electrokinetic chromatography. Journal of Pharmaceutical and Biomedical Analysis. doi:10.1016/j.jpba.2014.12.038

Liu, C., Li, H., Crommen, J., & Jiang, Z. (2015). Preparation and evaluation of novel zwitterionic HILIC monolithic columns [Paper presentation]. 43rd International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC), Beijing, China.

Wang, Q., Sanchez-Lopez, E., Han, H., Wu, H., Zhu, P., Crommen, J., Marina, M. L., & Jiang, Z. (2015). Separation of N-derivatized di- and tri-peptide stereoisomers by micro-liquid chromatography using a quinidine-based monolithic column - Analysis of l-carnosine in dietary supplements. Journal of Chromatography. A. doi:10.1016/j.chroma.2015.09.016

Wang, T., Feng, Y., Zhao, X., Guo, J., Zhou, Z., Crommen, J., & Jiang, Z. (2015). Reply to "a model lacking relevant literature comparison". Journal of Pharmaceutical and Biomedical Analysis, 104, 47-8. doi:10.1016/j.jpba.2014.10.029

Xiao, Y., Guo, J., Ran, D., Duan, Q., Crommen, J., & Jiang, Z. (2015). One-pot preparation of a sulfamethoxazole functionalized affinity monolithic column for selective isolation and purification of trypsin. Journal of Chromatography. A, 1400, 47-53. doi:10.1016/j.chroma.2015.04.046

Zhang, Q., Guo, J., Xiao, Y., Crommen, J., & Jiang, Z. (2015). Comparative evaluation of a one-pot strategy for the preparation of beta-cyclodextrin-functionalized monoliths: Effect of the degree of amino substitution of beta-cyclodextrin on the column performance. Journal of Separation Science, 38 (11), 1813-21. doi:10.1002/jssc.201500124

Lamalle, C., Baptiste, E., Marini Djang'Eing'A, R., Crommen, J., Hubert, P., Servais, A.-C., & Fillet, M. (May 2014). Développement de méthodes séparatives pour détecter la contrefaçon de molécules biosynthétiques comme l'insuline et les GHRP. Spectra Analyse, 43, 47-50.

Sacre, P.-Y., Deconinck, E., Marini Djang'Eing'A, R., Ziemons, E., Hubert, P., CHIAP, P., Crommen, J., & De Beer, J. O. (May 2014). Stratégies analytiques pour la détection de contrefaçons de médicaments pour la dysfonction érectile. Spectra Analyse, 43, 37.

Duan, Q., Liu, C., Liu, Z., Zhou, Z., Chen, W., Wang, Q., Crommen, J., & Jiang, Z. (2014). Preparation and evaluation of a novel monolithic column containing double octadecyl chains for reverse-phase micro high performance liquid chromatography. Journal of Chromatography. A, 1345, 174-81. doi:10.1016/j.chroma.2014.04.036

Feng, Y., Wang, T., Chankvetadze, B., Jiang, Z., & Crommen, J. (2014). Comparative enantiomer affinity pattern of beta-blockers in aqueous and non-aqueous CE using single-component anionic cyclodextrins [Paper presentation]. 21st International Symposium on Electro- and Liquid Phase-separation Techniques and 20th Latin American Symposium on Biotechnology, Biomedical, Biopharmaceutical and Industrial Applications of Capillary Electrophoresis and Microchip Technology (ITP & LACE), Natal, RGN, Brazil.

Fradi, I., Farcas, E., Said, A. B., Yans, M.-L., Lamalle, C., Somsen, G. W., Prior, A., de Jong, G. J., Kallel, M., Crommen, J., Servais, A.-C.* , & Fillet, M.*. (2014). In-capillary derivatization with (-)-1-(9-fluorenyl)ethyl chloroformate as chiral labeling agent for the electrophoretic separation of amino acids. Journal of Chromatography. A, 1363, 338-47. doi:10.1016/j.chroma.2014.07.022

Guo, J., Zhang, Q., Yao, Z., Zhao, X., Ran, D., Crommen, J., & Jiang, Z. (2014). One-step strategy for the synthesis of a derivatized cyclodextrin-based monolithic column. Journal of Separation Science, 37 (14), 1720-7. doi:10.1002/jssc.201400312

Houbart, V., Lecomte, F., COBRAIVILLE, G., Crommen, J., Hubert, P., & Fillet, M. (2014). Influence of sample and mobile phase composition on peptide retention behavior and detector response in miniaturized LC-MS [Poster presentation]. Hyphenated Techniques in Chromatography and Separation Technology 2014.

Jiang, Z., Guo, J., Zhang, Q., Yuan, G., Zhao, X., Liu, C., & Crommen, J. (2014). Functionalized polymeric monolithic columns in micro-HPLC for pharmaceutical analysis [Paper presentation]. 10th International Symposium on Drug Analysis and 25th Symposium on Pharmaceutical and Biomedical Analysis, Liege, Belgium.

Lamalle, C., Servais, A.-C., Crommen, J., & Fillet, M. (2014). Micellar electrokinetic chromatography against the counterfeiting of insulin formulations [Poster presentation]. 10th International Symposium on Drug Analysis 25th International Symposium on Pharmaceutical and Biomedical Analysis.

Liu, C., Chen, W., Yuan, G., Xiao, Y., Crommen, J., Xu, S., & Jiang, Z. (2014). Influence of the crosslinker type on the chromatographic properties of hydrophilic sulfoalkylbetaine-type monolithic columns. Journal of Chromatography. A, 1373, 73-80. doi:10.1016/j.chroma.2014.11.007

Servais, A.-C., Moldovan, R.-C., Farcas, E., Crommen, J., ROLAND, I., & Fillet, M. (2014). Development and validation of a liquid chromatographic method for the stability study of a pharmaceutical formulation containing voriconazole using cellulose tris(4-chloro-3-methylphenylcarbamate) as chiral selector and polar organic mobile phases. Journal of Chromatography. A, 1363, 178-82. doi:10.1016/j.chroma.2014.06.082

Wang, Q., Feng, J., Han, H., Zhu, P., Wu, H., Marina, M. L., Crommen, J., & Jiang, Z. (2014). Enantioseparation of N-derivatized amino acids by micro-liquid chromatography using carbamoylated quinidine functionalized monolithic stationary phase. Journal of Chromatography. A, 1363, 207-15. doi:10.1016/j.chroma.2014.06.039

Wang, T., Feng, Y., Chankvetadze, B., Jiang, Z., & Crommen, J. (2014). Enantioseparation of beta-blockers with different sulfated cyclodextrins in aqueous and non-aqueous CE with special emphasis on enantiomer affinity patterns [Paper presentation]. 30th International Symposium on Microscale Bioseparations (MSB), Pécs, Hungary.

Wang, T., Feng, Y., Jin, X., Fan, X., Crommen, J., & Jiang, Z. (2014). Liposome electrokinetic chromatography based in vitro model for early screening of the drug-induced phospholipidosis risk. Journal of Pharmaceutical and Biomedical Analysis, 96, 263-71. doi:10.1016/j.jpba.2014.03.043

Zhang, Q., Guo, J., Wang, F., Crommen, J., & Jiang, Z. (2014). Preparation of a beta-cyclodextrin functionalized monolith via a novel and simple one-pot approach and application to enantioseparations. Journal of Chromatography. A, 1325, 147-54. doi:10.1016/j.chroma.2013.12.019

Zhao, X., Chen, W., Liu, Z., Guo, J., Zhou, Z., Crommen, J., Moaddel, R., & Jiang, Z. (2014). A novel mixed phospholipid functionalized monolithic column for early screening of drug induced phospholipidosis risk. Journal of Chromatography. A, 1367, 99-108. doi:10.1016/j.chroma.2014.09.048

Houbart, V., Rozet, E., Matagne, A., Crommen, J., Servais, A.-C., & Fillet, M. (01 November 2013). Influence of sample and mobile phase composition on peptide retention behaviour and sensitivity in reversed-phase liquid chromatography/mass spectrometry. Journal of Chromatography. A, 1314, 199-207. doi:10.1016/j.chroma.2013.09.036

Houbart, V., Rozet, E., Crommen, J., Servais, A.-C., & Fillet, M. (June 2013). Développement de méthodes de quantification en milieu complexe par chromatographie liquide microfluidique couplée à la spectrometrie de masse [Paper presentation]. 10ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages, Paris, France.

Lamalle, C., Sacre, P.-Y., Marini Djang'Eing'A, R., Servais, A.-C., Hubert, P., Fillet, M., & Crommen, J. (June 2013). ANALYTICAL STRATEGIES FOR THE DETECTION AND CHARACTERIZATION OF COUNTERFEIT MEDICINES [Paper presentation]. 24th Symposium on Pharmaceutical and Biomedical Analysis (PBA2013) / RDPA 2013, Bologna, Italy.

Lamalle, C., Servais, A.-C., Crommen, J., & Fillet, M. (June 2013). L’électrophorèse capillaire micellaire pour la détermination simultanée de l’insuline et de ses analogues dans des formulations pharmaceutiques [Poster presentation]. SEP 2013 10ème congrès francophone sur les sciences séparatives.

Marini Djang'Eing'A, R., Fillet, M., Vancauwenberghe, R., Crommen, J., Frederich, M., & Hubert, P. (24 April 2013). Falsification des médicaments: mythe ou réalité ? [Paper presentation]. Cours-conférences 2013 Sciences Biologiques et Médicales, Namur, Belgium.

Esters, V., Karangwa, C., Tits, M., Francotte, P., Pirotte, B., Servais, A.-C., Fillet, M., Crommen, J., Robbrecht, E., MINET, A., Grisar, T., Angenot, L., & Frederich, M. (March 2013). Unusual Amino Acids and Monofluoroacetate from Dichapetalum michelsonii (Umutambasha), a Toxic Plant from Rwanda. Planta Medica, 79, 334-337. doi:10.1055/s-0032-1328283

Crommen, J., Houbart, V., Servais, A.-C., & Fillet, M. (2013). Quantification of fluoxetine and norfluoxetine by HPLC-Chip/MS2 [Paper presentation]. 11th Annual Congress of International Drug Discovery Science and Technology (IDDST), Haikou, Hainan, China.

Crommen, J., Servais, A.-C., Rousseau, A., & Fillet, M. (2013). Fast method development for chiral separations by non-aqueous capillary electrophoresis (NACE) [Paper presentation]. 2nd Annual Conference and Exposition of Analytics (AnalytiX), Suzhou, Jiansu, China.

Fradi, I., Lamalle, C., Kallel, M., Crommen, J., Servais, A.-C., & Fillet, M. (2013). Amino acids chiral separation by capillary electrophoresis with in-capillary sample preconcentration and chemical derivatisation [Paper presentation]. 29th International Symposium on Microscale Bioseparations (MSB), Charlottesville, VA, United States.

Guo, J., Zhang, Q., Peng, Y., Liu, Z., Rao, L., He, T., Crommen, J., Sun, P., & Jiang, Z. (2013). A facile and efficient one-step strategy for the preparation of beta-cyclodextrin monoliths. Journal of Separation Science, 36 (15), 2441-9. doi:10.1002/jssc.201300374

Houbart, V., Servais, A.-C., Crommen, J., & Fillet, M. (2013). Peptide behaviour in RP-HPLC coupled to MS: practical considerations based on a quantitative structure-retention relationship study [Paper presentation]. 39th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC), Amsterdam, Netherlands.

Houbart, V., Servais, A.-C., Crommen, J., & Fillet, M. (2013). Influence of sample and mobile phase composition on peptide retention behaviour and detector response in LC-MS [Paper presentation]. 40th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC), Hobart, Tasmania, Australia.

Lamalle, C., Servais, A.-C., Crommen, J., & Fillet, M. (2013). Simultaneous determination of insulin and its analogues in pharmaceutical formulations by micellar electrokinetic chromatography (MEKC) [Poster presentation]. 24th INTERNATIONAL SYMPOSIUM ON PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, Bologna, Italy.

Peng, Y., Zhang, T., Wang, T., Liu, Z., Crommen, J., & Jiang, Z. (2013). Use of neutral capillaries for the enantioseparation of N-benzoylated amino acids by capillary electrophoresis with bromobalhimycin as chiral selector. Journal of Separation Science, 36 (9-10), 1568-74. doi:10.1002/jssc.201300005

Yuan, G., Peng, Y., Liu, Z., Hong, J., Xiao, Y., Guo, J., Smith, N. W., Crommen, J., & Jiang, Z. (2013). A facile and efficient strategy to enhance hydrophilicity of zwitterionic sulfoalkylbetaine type monoliths. Journal of Chromatography. A, 1301, 88-97. doi:10.1016/j.chroma.2013.05.063

Kohn, G., Delvaux, D., Lakaye, B., Servais, A.-C., Scholer, G., Fillet, M., Elias, B., Derochette, J.-M., Crommen, J., Wins, P., & Bettendorff, L. (12 September 2012). High inorganic triphosphatase activities in bacteria and mammalian cells: Identification of the enzymes involved. PLoS ONE, 7 (9), 43879. doi:10.1371/journal.pone.0043879

Lamalle, C., Marini Djang'Eing'A, R., Debrus, B., Lebrun, P., Crommen, J., Hubert, P., Servais, A.-C., & Fillet, M. (07 August 2012). Development of a generic micellar electrokinetic chromatography method for the separation of 15 antimalarial drugs as a tool to detect medicine counterfeiting. Electrophoresis, 33, 1669-1678. doi:10.1002/elps.201100621

Chankvetadze, L., Servais, A.-C., Fillet, M., Salgado, A., Crommen, J., & Chankvetadze, B. (2012). Comparative enantioseparation of talinolol in aqueous and non-aqueous capillary electrophoresis and study of related selector-selectand interactions by nuclear magnetic resonance spectroscopy. Journal of Chromatography. A, 1267, 206-16. doi:10.1016/j.chroma.2012.08.063

Crommen, J., Dossou, K. S. S., Farcas, E., Servais, A.-C., & Fillet, M. (2012). HPLC separation and determination of drug enantiomers using chlorine-containing cellulose-based chiral stationary phases and polar organic mobiles phases [Paper presentation]. 10th Annual Congress of International Drug Discovery Science and Technology (IDDST), Nanjing, Jiangsu, China.

Crommen, J., Houbart, V., Servais, A.-C., & Fillet, M. (2012). High sensitivity plasma determination of hepcidin, a peptide biomarker for iron metabolism, using HPLC-Chip-ESI-MS [Paper presentation]. 5th Annual Congress and Exposition of Molecular Diagnostics (CEMD), Guangzhou, Guangdong, China.

Dossou, K. S. S., Farcas, E., Servais, A.-C., CHIAP, P., Chankvetadze, B., Crommen, J., & Fillet, M. (2012). Optimization of the liquid chromatography enantioseparation of chiral acidic compounds using cellulose tris(3-chloro-4-methylphenylcarbamate) as chiral selector and polar organic mobile phases. Journal of Chromatography. A, 1234, 56-63. doi:10.1016/j.chroma.2012.01.072

Fradi, I., Servais, A.-C., Lamalle, C., Kallel, M., Abidi, M., Crommen, J., & Fillet, M. (2012). Chemo- and enantio-selective method for the analysis of amino acids by capillary electrophoresis with in-capillary derivatization. Journal of Chromatography. A, 1267, 121-6. doi:10.1016/j.chroma.2012.05.098

Houbart, V., Servais, A.-C., Crommen, J., & Fillet, M. (2012). Microfluidics-based LC-CHIP-MS/MS method for fluoxetine and norfluoxetine in rat serum [Paper presentation]. 16th Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

Houbart, V., Servais, A.-C., Crommen, J., & Fillet, M. (2012). Development of LC-chip-nano-ESI-MS/MS methods for high sensitivity quantitation in complex matrix [Paper presentation]. 27th International symposium on Microscale Bioseparations and Analysis (MSB 2012), Geneva, Switzerland.

Houbart, V., Servais, A.-C., Crommen, J., & Fillet, M. (2012). Development and validation a LC-chip-MS/MS method for the quantitation of fluoxetine and norfluoxetine in rat serum [Poster presentation]. 19th International Symposium, Exhibit & Workshops on Electro- and Liquid Phase-separation Techniques, Baltimore, United States - Maryland.

Lamalle, C., Servais, A.-C., Crommen, J., & Fillet, M. (2012). Migration behaviour study of charged and uncharged compounds in micellar electrokinetic chromatography systems containing various proportions of SDS micelles and acetonitrile as organic modifier [Poster presentation]. 27th International Symposium on MicroScale Bioseparations and Analyses, Genève, Switzerland.

Lamalle, C., Servais, A.-C., Fradi, I., Crommen, J., & Fillet, M. (2012). Micellar electrokinetic chromatography systems for the separation of mixtures of charged and uncharged compounds. Journal of Separation Science, 35 (15), 1933-1939. doi:10.1002/jssc.201200293

Lamalle, C., Servais, A.-C., Fradi, I., Crommen, J., & Fillet, M. (2012). Micellar electrokinetic chromatography (MEKC) systems for the separation of mixtures of charged and uncharged compounds [Poster presentation]. 19th International Symposium on Electro- and Liquid Phase-separation Techniques (ITP), Baltimore, United States.

Servais, A.-C., Fillet, M., Chankvetadze, B., & Crommen, J. (2012). Comparative enantioseparation of chiral drug compounds with different cyclodextrins in aqueous and non-aqueous CE and study of related selector-solute interactions by NMR spectroscopy [Paper presentation]. 19th International Symposium on Electro- and Liquid Phase-separation Techniques (ITP), Baltimore, MA, United States.

Servais, A.-C., Rousseau, A., Dive, G., Frederich, M., Crommen, J., & Fillet, M. (2012). Combination of capillary electrophoresis, molecular modelling and nuclear magnetic resonance to study the interaction mechanisms between single-isomer anionic cyclodextrin derivatives and basic drug enantiomers in a methanolic background electrolyte. Journal of Chromatography. A, 1232, 59-64. doi:10.1016/j.chroma.2011.10.010

Lamalle, C., Marini Djang'Eing'A, R., Debrus, B., Lebrun, P., Crommen, J., Hubert, P., Servais, A.-C., & Fillet, M. (September 2011). GENERIC MEKC METHOD FOR THE SEPARATION OF 15 ANTIMALARIAL DRUGS [Poster presentation]. Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy.

Sacré, P.-Y., Deconinck, E., Daszykowski, M., Courselle, P., Vancauwenberghe, R., Chiap, P., Crommen, J., & De Beer, J. (September 2011). Impurity fingerprints for the identification of counterfeit medicines - a feasibility study [Poster presentation]. Recent Developments in Pharmaceutical Analysis (RDPA), Pavie, Italy.

Mansion, F., Chiap, P., Houbart, V., Crommen, J., Servais, A.-C., & Fillet, M. (July 2011). Optimization of micro-HPLC peak focusing for the detection and quantification of low hepcidin concentrations. Journal of Separation Science, 34 (15), 1820-1827. doi:10.1002/jssc.201100244

Sacré, P.-Y., deconinck, E., Daszykowski, M., Courselle, P., Vancauwenberghe, R., Chiap, P., Crommen, J., & De Beer, J. (22 June 2011). Impurity fingerprints for the identification of counterfeit medicines - a feasibility study [Poster presentation]. HPLC 2011, Budapest, Hungary.

Sacré, P.-Y., Deconinck, E., Chiap, P., Crommen, J., Mansion, F., Rozet, E., Courselle, P., & De Beer, J. (20 June 2011). Development and validation of a UHPLC-UV method for the detection and quantification of erectile dysfunction drugs and some of their analogues found in counterfeit medicines [Poster presentation]. HPLC 2011, Budapest, Hungary.

Lamalle, C., Marini Djang'Eing'A, R., Debrus, B., Lebrun, P., Servais, A.-C., Crommen, J., Hubert, P., & Fillet, M. (June 2011). Development of a Generic MEKC Method for the Separation of 15 Antimalarial Drugs by a Design Space Approach [Poster presentation]. 36th International symposium on HPLC and Related Techniques, Budapest, Hungary.

Servais, A.-C., Rousseau, A., Dive, G., Frederich, M., Crommen, J., & Fillet, M. (June 2011). Combination of capillary electrophoresis, molecular modelling and nuclear magnetic resonance to study the interaction mechanisms between single-isomer anionic CD derivatives and basic drug enantiomers in a methanolic background electrolyte [Poster presentation]. 36th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2011), Budapest, Hungary.

Sacré, P.-Y., Deconinck, E., Saerens, L., De Beer, T., Courselle, P., Vancauwenberghe, R., Chiap, P., Crommen, J., & De Beer, J. (13 May 2011). Detection of counterfeit Viagra by Raman microspectroscopy imaging and multivariate analysis [Paper presentation]. 15ème Forum des Sciences Pharmaceutiques, Spa, Belgium.

Servais, A.-C., Rousseau, A., Dive, G., Frederich, M., Pirotte, B., Crommen, J., & Fillet, M. (23 March 2011). Systèmes génériques pour la séparation d’énantiomères de molécules basiques et acides à l’aide de cyclodextrines en électrophorèse capillaire en milieu non aqueux [Paper presentation]. 9ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages (SEP 11), Toulouse, France.

Crommen, J., Rousseau, A., Fradi, I., Servais, A.-C., & Fillet, M. (2011). Enantioseparations in non-aqueous capillary electrophoresis (NACE) [Paper presentation]. 18th International Symposium on Electro- and Liquid Phase-Separation Techniques (ITP), Tbilisi, Georgia.

Dossou, K. S. S., Chiap, P., Chankvetadze, B., Servais, A.-C., Fillet, M., & Crommen, J. (2011). LC enantioseparation of basic pharmaceuticals using chlorine containing cellulose based chiral stationary phases and polar organic mobile phases [Paper presentation]. Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy.

Dossou, K. S. S., CHIAP, P., Servais, A.-C., Fillet, M., & Crommen, J. (2011). Evaluation of chlorine containing cellulose-based chiral stationary phases for the LC enantioseparation of basic pharmaceuticals using polar non-aqueous mobile phases. Journal of Separation Science, 34 (6), 617-22. doi:10.1002/jssc.201000774

Dossou, K. S. S., CHIAP, P., Servais, A.-C., Fillet, M., & Crommen, J. (2011). Development and validation of a LC method for the enantiomeric purity determination of S-ropivacaine in a pharmaceutical formulation using a recently commercialized cellulose-based chiral stationary phase and polar non-aqueous mobile phase. Journal of Pharmaceutical and Biomedical Analysis, 54 (4), 687-93. doi:10.1016/j.jpba.2010.10.020

Dossou, K. S. S., Edorh, P. A., Chiap, P., Chankvetadze, B., Servais, A.-C., Fillet, M., & Crommen, J. (2011). Determination of enantiomeric purity of S-amlodipine by chiral LC with emphasis on reversal of enantiomer elution order. Journal of Separation Science, 34, 1772-1780. doi:10.1002/jssc.201100339

Martin, G., Mansion, F., Houbart, V., PAQUET, P., RORIVE, A., CHIAP, P., Crommen, J., Servais, A.-C., & Fillet, M. (2011). Pre-study and in-study validation of a SPE-LC-MS-MS method for the determination of 5-S-cysteinyldopa, a melanoma biomarker, in human plasma. Talanta, 84 (2), 280-6. doi:10.1016/j.talanta.2010.12.047

Rousseau, A., Gillotin, F., Chiap, P., Bodoki, E., Crommen, J., Fillet, M., & Servais, A.-C. (2011). Generic systems for the enantioseparation of basic drugs in NACE using single-isomer anionic CDs. Journal of Pharmaceutical and Biomedical Analysis, 54, 154-159. doi:10.1016/j.jpba.2010.08.004

Sacré, P.-Y., Deconinck, E., Chiap, P., Crommen, J., Mansion, F., Rozet, E., Courselle, P., & De Beer, J. (2011). Development and validation of a ultra-high-performance liquid chromatography-UV method for the detection and quantification of erectile dysfunction drugs and some of their analogues found in counterfeit medicines. Journal of Chromatography. A, 1218, 6439-6447. doi:10.1016/j.chroma.2011.07.029

Sacré, P.-Y., Deconinck, E., Daszykowski, M., Courselle, P., Vancauwenberghe, R., Chiap, P., Crommen, J., & De Beer, J. (2011). Impurity fingerprints for the identification of counterfeit medicines - a feasibility study. Analytica Chimica Acta, 701, 224-231. doi:10.1016/j.aca.2011.05.041

Sacré, P.-Y.* , Deconinck, E.* , Saerens, L., De Beer, T., Courselle, P., Vancauwenberghe, R., Chiap, P., Crommen, J., & De Beer, J. (2011). Detection of counterfeit Viagra® by Raman Microspectroscopy imaging and multivariate analysis. Journal of Pharmaceutical and Biomedical Analysis, 56, 454-461. doi:10.1016/j.jpba.2011.05.042

Servais, A.-C., Rousseau, A., CHIAP, P., Fillet, M., & Crommen, J. (2011). Determination of drug enantiomers in various matrices by non-aqueous capillary electrophoresis (NACE) [Paper presentation]. 23rd International Symposium on Pharmaceutical and Biomedical Analysis (PBA), Joao Pessoa PB, Brazil.

Servais, A.-C., Rousseau, A., Fillet, M., & Crommen, J. (2011). Fast method development for the enantioseparation of acidic and basic compounds by non-aqueous capillary electrophoresis (NACE) [Paper presentation]. 17th International Symposium on Separation Sciences (ISSS), Cluj-Napoca, Romania.

Sacré, P.-Y., Deconinck, E., De Beer, T., Courselle, P., Vancauwenberghe, R., Chiap, P., Crommen, J., & De Beer, J. (23 September 2010). Comparison and combination of spectroscopic techniques for the detection of counterfeit medicines [Poster presentation]. Drug Analysis 2010, Anvers, Belgium.

Fillet, M., Servais, A.-C., Rousseau, A., Fradi, I., Chankvetadze, B., & Crommen, J. (September 2010). Cyclodextrin-based Chiral Separations by Capillary Electrophoresis in J. Crommen’s lab : a Twenty Years Story [Paper presentation]. Drug Analysis 2010, Antwerp, Belgium.

Fradi, I., Servais, A.-C., Kallel, M., Oueslati, H., Crommen, J., & Fillet, M. (September 2010). Amino acids chiral separation by capillary electrophoresis with in-capillary sample preconcentration and chemical derivatisation [Paper presentation]. Drug Analysis 2010, Antwerp, Belgium.

Houbart, V., Lecomte, F., Cobraiville, G., Crommen, J., Hubert, P., & Fillet, M. (September 2010). A LC-chip nanoelectrospray MS/MS method for hepcidin quantitation in human plasma [Poster presentation]. 9th International Symposium on Drug Analysis - 22nd International Symposium on Pharmaceutical and Biomedical Analysis, Antwerp, Belgium.

Lamalle, C., Marini Djang'Eing'A, R., Debrus, B., Servais, A.-C., Crommen, J., Hubert, P., & Fillet, M. (September 2010). A DESIGN SPACE APPROACH TO DEVELOP A GENERIC CE METHOD FOR THE SEPARATION OF 19 ANTIMALARIAL DRUGS [Poster presentation]. International Symposium on Drug Analysis, Anvers, Belgium.

Servais, A.-C., Rousseau, A., Fillet, M., Lomsadze, K., Salgado, A., Crommen, J., & Chankvetadze, B. (September 2010). Combination of capillary electrophoresis and nuclear magnetic resonance spectroscopy to study the opposite affinity pattern of propranolol enantiomers towards various cyclodextrins [Poster presentation]. Drug Analysis 2010, Anvers, Belgium.

Rousseau, A., Florence, X., Pirotte, B., Varenne, A., Gareil, P., Villemin, D., Chiap, P., Crommen, J., Fillet, M., & Servais, A.-C. (March 2010). Development and validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of a synthetic intermediate of new R/S-3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans using a single-isomer anionic cyclodextrin derivative and an ionic liquid [Poster presentation]. 25th International Symposium on MicroScale Bioseparations (MSB 2010), Prague, Czechia.

Rousseau, A., Gillotin, F., Chiap, P., Crommen, J., Servais, A.-C., & Fillet, M. (March 2010). Association of two single-isomer anionic CDs in NACE for the chiral and achiral separation of fenbendazole, its sulphoxide and sulphone metabolites: Application to their determination after in vitro metabolism [Poster presentation]. 25th International Symposium on MicroScale Bioseparations (MSB 2010), Prague, Czechia.

Servais, A.-C., Rousseau, A., Chankvetadze, B., Crommen, J., & Fillet, M. (March 2010). Enantioseparation using sulfated beta-cyclodextrins in aqueous and nonaqueous capillary electrophoresis: Study of the mechanisms of enantioselective intermolecular interactions [Poster presentation]. 25th International Symposium on MicroScale Bioseparations (MSB 2010), Prague, Czechia.

Crommen, J., Rousseau, A., Fradi, I., CHIAP, P., Fillet, M., & Servais, A.-C. (2010). Selective determination of drug enantiomers by non-aqueous capillary electrophoresis [Paper presentation]. 14th National Congress of Pharmacy (CNFR), Targu-Mures, Romania.

Crommen, J., Rousseau, A., Fradi, I., Servais, A.-C., & Fillet, M. (2010). L’électrophorèse capillaire: un outil de choix pour l’analyse chirale [Paper presentation]. 3ème Congrès des Sciences Analytiques (CSA), Casablanca, Morocco.

Dossou, K. S. S., Chiap, P., Chankvetadze, B., Servais, A.-C., Fillet, M., & Crommen, J. (2010). Optimization of the LC enantioseparation of chiral pharmaceuticals using cellulose tris(4-chloro-3-methylphenylcarbamate) as chiral selector and polar non-aqueous mobile phases. Journal of Separation Science, 33, 1699-1707. doi:10.1002/jssc.201000049

Rousseau, A., Florence, X., Pirotte, B., Varenne, A., Gareil, P., Villemin, D., Chiap, P., Crommen, J., Fillet, M., & Servais, A.-C. (2010). Development and validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of a synthetic intermediate of new 3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans using a single-isomer anionic cyclodextrin derivative and an ionic liquid. Journal of Chromatography. A, 1217 (51), 7949-55. doi:10.1016/j.chroma.2010.07.005

Rousseau, A., Gillotin, F., Chiap, P., Crommen, J., Fillet, M., & Servais, A.-C. (2010). Association of two single-isomer anionic CD in NACE for the chiral and achiral separation of fenbendazole, its sulphoxide and sulphone metabolites: Application to their determination after in vitro metabolism. Electrophoresis, 31, 1482-1487. doi:10.1002/elps.200900723

Sacré, P.-Y., Deconinck, E., De Beer, T., Courselle, P., Vancauwenberghe, R., Chiap, P., Crommen, J., & De Beer, J. (2010). Comparison and combination of spectroscopic techniques for the detection of counterfeit medicines. Journal of Pharmaceutical and Biomedical Analysis, 53, 445-453. doi:10.1016/j.jpba.2010.05.012

Servais, A.-C., Crommen, J., & Fillet, M. (2010). Factors Influencing Cyclodextrin-Mediated Chiral Separations. In Chiral Separations by Capillary Electrophoresis (pp. 87-107). Boca Raton, United States - Florida: CRC Press.

Servais, A.-C., Fillet, M., Mol, R., Rousseau, A., Crommen, J., Somsen, G. W., & de Jong, G. J. (2010). Influence of the BGE composition on analyte response in CD-mediated NACE-MS. Electrophoresis, 31 (7), 1157-1161. doi:10.1002/elps.200900649

Servais, A.-C., Rousseau, A., Fillet, M., Lomsadze, K., Salgado, A., Crommen, J., & Chankvetadze, B. (2010). Separation of propranolol enantiomers by CE using sulfated beta-CD derivatives in aqueous and non-aqueous electrolytes: Comparative CE and NMR study. Electrophoresis, 31, 1467-1474. doi:10.1002/elps.200900738

Servais, A.-C., Rousseau, A., Fillet, M., Lomsadze, K., Salgado, A., Crommen, J., & Chankvetadze, B. (2010). Capillary electrophoretic and nuclear magnetic resonance studies on the opposite affinity pattern of propranolol enantiomers towards various cyclodextrins. Journal of Separation Science, 33, 1617-1624. doi:10.1002/jssc.201000040

Crommen, J., Rousseau, A., Chankvetadze, B., Fillet, M., & Servais, A.-C. (2009). Contribution à l’étude des mécanismes de reconnaissance chirale intervenant lors de la séparation énantiomérique à l’aide de cyclodextrines en électrophorèse capillaire en milieux aqueux et non aqueux [Paper presentation]. 8ème Congrès francophone sur les techniques séparatives et les couplages (SEP'09), Marseille, France.

Crommen, J., Servais, A.-C., Fillet, M., Rousseau, A., Somsen, G. W., & De Jong, G. J. (2009). Influence of the BGE composition on ionization performance in CD mediated NACE-ESI-MS [Paper presentation]. 24th International Symposium on MicroScale Bioseparations (MSB), Dalian, Liaoning, China.

Dossou, K. S. S., Chiap, P., Chankvetadze, B., Servais, A.-C., Crommen, J., & Fillet, M. (2009). Evaluation of recently developed cellulose based chiral stationary phases for the LC enantioseparation of basic pharmaceuticals using polar non-aqueous mobile phases [Poster presentation]. 34th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2009), Dresden, Germany.

Dossou, K. S. S., Chiap, P., Chankvetadze, B., Servais, A.-C., Fillet, M., & Crommen, J. (2009). Enantioresolution of basic pharmaceuticals using cellulose tris(4-chloro-3-methylphenylcarbamate) as chiral stationary phase and polar organic mobile phases. Journal of Chromatography. A, 1216 (44), 7450-5. doi:10.1016/j.chroma.2009.05.081

Martin, G., Mansion, F., Servais, A.-C., Debrus, B., Rozet, E., Hubert, P., Crommen, J., & Fillet, M. (2009). CE-MS method development for peptides analysis, especially hepcidin, an iron metabolism marker. Electrophoresis, 30 (15), 2624-31. doi:10.1002/elps.200800794

Rousseau, A., Chiap, P., Oprean, R., Crommen, J., Fillet, M., & Servais, A.-C. (2009). Effect of the nature of the single-isomer anionic cyclodextrin and the BGE composition on the enantiomeric separation of β-blockers in nonaqueous capillary electrophoresis [Poster presentation]. 34th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2009), Dresden, Germany.

Rousseau, A., Chiap, P., Oprean, R., Crommen, J., Fillet, M., & Servais, A.-C. (2009). Effect of the nature of the single-isomer anionic CD and the BGE composition on the enantiomeric separation of beta-blockers in NACE. Electrophoresis, 30 (16), 2862-8. doi:10.1002/elps.200800824

Rozet, E., Mantanus, J., Ziemons, E., Boulanger, B., Dewe, W., Crommen, J., & Hubert, P. (2009). Practical Implementation of Total Error for the Validation of Chromatographic and Ligand Binding Assays [Paper presentation]. PharmSciFair.

Servais, A.-C., Rousseau, A., CHIAP, P., Fradi, I., Fillet, M., & Crommen, J. (2009). Recent developments in enantioseparations of acidic and basic drug compounds by non-aqueous capillary electrophoresis using charged cyclodextrins as chiral selectors [Paper presentation]. 20th International Symposium on Pharmaceutical and Biomedical Analysis (PBA), Agra, India.

Servais, A.-C., Rousseau, A., Fillet, M., Somsen, G. W., De Jong, G. J., & Crommen, J. (2009). Separation and quantification of low amounts of drug enantiomers using chiral non-aqueous CE with charged cyclodextrins and UV or MS detection [Paper presentation]. 15th Latin American Symposium on Biotechnology, Biomedical, Biopharmaceutical and Industrial Applications of Capillary Electrophoresis and Microchip Technology (LACE), Seville, Spain.

Bimazubute, M. A., Rozet, E., Dizier, I., Gustin, P., Hubert, P., Crommen, J., & Chiap, P. (2008). Liquid chromatographic determination of enrofloxacin in nasal secretions and plasma of healthy pigs using restricted access material for on-line sample clean-up. Journal of Chromatography. A, 1189 (1-2), 456-466. doi:10.1016/j.chroma.2007.11.011

Dossou, K. S. S., Chiap, P., Servais, A.-C., Fillet, M., & Crommen, J. (2008). Comparison of different cellulose based chiral stationary phases for the LC enantioseparation of basic drugs using polar organic mobile phases [Paper presentation]. 19th International Symposium on pharmaceutical and biomedical analysis (PBA 2008), Gdansk, Poland.

Dossou, K. S. S., Chiap, P., Servais, A.-C., Fillet, M., & Crommen, J. (2008). A screening study of chiral pharmaceuticals using tris(4-chloro-3-methylphenylcarbamate) of cellulose-based stationary phase and polar organic mobile phases [Poster presentation]. 33rd International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2008), Kyoto, Japan.

Rousseau, A., Chiap, P., Ivanyi, R., Crommen, J., Fillet, M., & Servais, A.-C. (2008). Validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of R-flurbiprofen using a single-isomer amino cyclodextrin derivative. Journal of Chromatography. A, 1204 (2), 219-225. doi:10.1016/j.chroma.2008.06.006

Rousseau, A., Chiap, P., Ivanyi, R., Crommen, J., Fillet, M., & Servais, A.-C. (2008). Validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of R-flurbiprofen using a single-isomer amino cyclodextrin derivative [Poster presentation]. 22nd International Symposium on MicroScale Bioseparations (MSB 2008), Berlin, Germany.

Rousseau, A., Pedrini, M., Chiap, P., Ivanyi, R., Crommen, J., Fillet, M., & Servais, A.-C. (2008). Determination of flurbiprofen enantiomers in plasma using a single-isomer amino cyclodextrin derivative in nonaqueous capillary electrophoresis. Electrophoresis, 29 (17), 3641-8. doi:10.1002/elps.200700919

Rozet, E., Dewé, W., Morello, R., Chiap, P., Lecomte, F., Ziemons, E., Boos, K. S., Boulanger, B., Crommen, J., & Hubert, P. (2008). Risk-Based Approach for the Transfer of Quantitative Methods: Bioanalytical Applications. Journal of Chromatography. A, 1189, 32-41. doi:10.1016/j.chroma.2007.11.029

Servais, A.-C., Fillet, M., Rousseau, A., Somsen, G., de Jong, G. J., & Crommen, J. (2008). Influence of the background electrolyte composition and electrospray parameters on the analyte response in cyclodextrin mediated nonaqueous capillary electrophoresis-mass spectrometry [Paper presentation]. 33rd International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2008), Kyoto, Japan.

Lecomte, F., Aerts, J., Plenevaux, A., Lignon, S., Chapuis-Hugon, F., Chiap, P., Crommen, J., Luxen, A., Pichon, V., & Hubert, P. (September 2007). PPERFORMANCE EVALUATION OF TWO MIPS FOR THE SPE-LC-UV DETERMINATION OF p-[18F]MPPF IN PLASMA [Poster presentation]. RDPA 2007, 12th Internatioinal Meeting on Recent Developments in Pharmaceutical Analysis, Island of Elba, Italy.

Mol, R., Servais, A.-C., Fillet, M., Crommen, J., de Jong, G. J., & Somsen, G. W. (03 August 2007). Nonaqueous electrokinetic chromatography-electrospray ionization mass spectrometry using anionic cyclodextrins. Journal of Chromatography. A, 1159 (1-2), 51-57. doi:10.1016/j.chroma.2007.05.050

Lecomte, F., Aerts, J., Plenevaux, A., Lignon, S., Denjean, C., Chapuis-Hugon, F., Chiap, P., Crommen, J., Luxen, A., Pichon, V., & Hubert, P. (June 2007). DEVELOPMENT AND VALIDATION OF A METHOD FOR THE LC DETERMINATION p-[18F]MPPF IN PLASMA USING A MISPE [Poster presentation]. HPLC 2007 - 31st International Symposium on High Performance Liquid Phase Separations and Related Techniques, Ghent, Belgium.

Marini Djang'Eing'A, R., Servais, A.-C., Rozet, E., Chiap, P., Boulanger, B., Rudaz, S., Crommen, J., Hubert, P., & Fillet, M. (June 2007). Enantiomeric purity testing of S-timolol by non-aqueous CE using heptakis(2,3-di-O-methyl-6-O-Sulfo)-β-cyclodextrin as chiral additive – Validation using the accuracy profile strategy and estimation of uncertainty [Poster presentation]. 31st International Symposium on HPLC and Related techniques, Gand, Belgium.

Dossou, K. S. S., Chiap, P., Servais, A.-C., Fillet, M., & Crommen, J. (2007). HPLC enantioseparations of basic drugs using recently developed polysaccharide based chiral stationary phases and polar organic mobile phases [Paper presentation]. 12th International meeting on recent developments in pharmaceutical analysis (RDPA 2007), Elba, Italy.

Dossou, K. S. S., Ghiani, S., Chiap, P., Servais, A.-C., Fillet, M., & Crommen, J. (2007). HPLC enantioseparation of basic pharmaceuticals using a new polysaccharide based chiral stationary phase and non-aqueous polar mobile phases [Poster presentation]. 31st International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2007), Ghent, Belgium.

Lecomte, F., Aerts, J., Houbart, V., Plenevaux, A., Lignon, S., Chiap, P., Crommen, J., Luxen, A., Pichon, V., & Hubert, P. (2007). EVALUATION DE DEUX POLYMERES A EMPREINTES MOLECULAIRES POUR LE DOSAGE DU p-[18F]MPPF DANS LE PLASMA [Poster presentation]. 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages - SEP07, Grenoble, France.

Mansion, F., Chen, F., Martin, G., Servais, A.-C., Rozet, E., Hubert, P., Crommen, J., & Fillet, M. (2007). Study of the influence of the peak focusing effect in capillary LC columns on detection sensitivity - application to the determination of low concentrations of hepcidine in biofluids [Poster presentation]. 31st international symposium on high performance liquid phase separations and related techniques, Gand, Belgium.

Marini Djang'Eing'A, R., Rozet, E., Vanderheyden, Y., Ziemons, E., Boulanger, B., Bouklouze, A., Servais, A.-C., Fillet, M., Crommen, J., & Hubert, P. (2007). Robustness testing of a chiral NACE method for R-timolol determination in S-timolol maleate and uncertainty assessment from quantitative data. Journal of Pharmaceutical and Biomedical Analysis, 44 (3), 640-51. doi:10.1016/j.jpba.2006.08.018

Martin, G., Chiap, P., Paquet, P., Pierard, G., De Tullio, P., Martin, Y., Rozet, E., Hubert, P., Crommen, J., & Fillet, M. (2007). Development of a mass spectrometry method for the determination of a melanoma biomarker, 5-S-cysteinyldopa, in human plasma using solid phase extraction for sample clean-up. Journal of Chromatography. A, 1156 (1-2), 141-8. doi:10.1016/j.chroma.2006.12.088

Rousseau, A., Pedrini, M., Chiap, P., Fillet, M., Crommen, J., & Servais, A.-C. (2007). Determination of flurbiprofen enantiomers in plasma using a single-isomer amino cyclodextrin derivative in non-aqueous capillary electrophoresis [Poster presentation]. 31st International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2007), Ghent, Belgium.

Rozet, E., Dewe, W., Govaerts, B., Boulanger, B., Ceccato, A., Chiap, P., Crommen, J., & Hubert, P. (2007). Evaluation of Analytical Method Transfer on a Risk Based Methodology using Total Error [Paper presentation]. HPLC.

Rozet, E., Dewe, W., Govaerts, B., Boulanger, B., Moonen, F., Crommen, J., & Hubert, P. (2007). PAT COMPLIENT APPROACHES TO ASSESS THE ACCEPTABILITY OF ANALYTICAL METHOD TRANSFER: HOW TO LIMIT THE RISK TO OBTAIN OOS RESULTS? [Poster presentation]. RDPA - 12th international meeting on Recent Development in Pharmaceutical Analysis.

Servais, A.-C., Rousseau, A., Pedrini, M., Crommen, J., & Fillet, M. (2007). Enantioseparation of pharmaceutical compounds using single-isomer cyclodextrin derivatives as chiral additives in nonaqueous capillary electrophoresis [Paper presentation]. 31st International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2007), Ghent, Belgium.

Rozet, E., Morello, R., Lecomte, F., Martin, G. B., Chiap, P., Crommen, J., Boos, K.-S., & Hubert, P. (05 December 2006). Performances of a multidimensional on-line SPE-LC-ECD method for the determination of three major catecholamines in native human urine: Validation, risk and uncertainty assessments. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 844 (2), 251-260. doi:10.1016/j.jchromb.2006.07.060

Marini Djang'Eing'A, R., Chiap, P., Boulanger, B., Rudaz, S., Rozet, E., Crommen, J., & Hubert, P. (November 2006). Comparaison de trois approches pour l'estimation de l'incertitude [Paper presentation]. 3ème journée internationale de toxicologie hospitalière, Liège, Belgium.

Hubert, P., Rozet, E., Crommen, J., Dewé, W., & Boulanger, B. (28 September 2006). développement récent dans le domaine de la validation des méthodes analytiques [Paper presentation]. 13e Congrès National de Pharmacie, Cluj-Napoca, Romania.

Rozet, E., Mertens, B., Dewé, W., Ceccato, A., Govaerts, B., Boulanger, B., Chiap, P., Streel, B., Crommen, J., & Hubert, P. (11 September 2006). The transfer of a LC-UV method for the determination of fenofibrate and fenofibric acid in Lidoses: Use of total error as decision criterion. Journal of Pharmaceutical and Biomedical Analysis, 42 (1), 64-70. doi:10.1016/j.jpba.2005.12.037

Fradi, I.* , Servais, A.-C.* , Pedrini, M., Chiap, P., Ivanyi, R., Crommen, J., & Fillet, M. (September 2006). Enantiomeric separation of acidic compounds using single-isomer amino cyclodextrin derivatives in nonaqueous capillary electrophoresis. Electrophoresis, 27 (17), 3434-3442. doi:10.1002/elps.200500643

Servais, A.-C., Crommen, J., & Fillet, M. (July 2006). Capillary electrophoresis-mass spectrometry, an attractive tool for drug bioanalysis and biomarker discovery. Electrophoresis, 27 (13), 2616-2629. doi:10.1002/elps.200500934

Marini Djang'Eing'A, R., Rozet, E., Ziemons, E., Chiap, P., Boulanger, B., Rudaz, S., Servais, A.-C., Fillet, M., Crommen, J., & Hubert, P. (May 2006). COMPARISON OF THREE DIFFERENT APPROACHES FOR UNCERTAINTY ESTIMATION CONSIDERING LC AND CE METHODS [Paper presentation]. A joint meeting of two distinguished series: the 8th International Symposium on Drug Analysis and the 17th International Symposium on Pharmaceutical and Biomedical Analysis, Namur, Belgium.

Lecomte, F., Boulanger, B., Hall, A. J., Sellergren, B., Crommen, J., Chiap, P., & Hubert, P. (March 2006). Développement d’une méthode de dosage automatisé du méthotrexate dans le plasma humain par couplage direct à la chromatographie liquide de l’extraction sur phase solide à empreintes moléculaires [Poster presentation]. Forum LABO & Forum BIOTECH 2006, Paris, France.

Servais, A.-C.* , Fillet, M.* , Mol, R., Somsen, G. W., Chiap, P., de Jong, G. J., & Crommen, J. (February 2006). On-line coupling of cyclodextrin mediated nonaqueous capillary electrophoresis to mass spectrometry for the determination of salbutamol enantiomers in urine. Journal of Pharmaceutical and Biomedical Analysis, 40 (3), 752-757. doi:10.1016/j.jpba.2005.08.004

Crommen, J., Servais, A.-C., Fradi, I., Chiap, P., & Fillet, M. (2006). Enantiomeric separation of acidic compounds in nonaqueous capillary electrophoresis using single-isomer amino cyclodextrin derivatives as chiral selectors [Paper presentation]. 20th International Symposium on Microscale Bioseparations, Amsterdam, Netherlands.

Crommen, J., Servais, A.-C., Rousseau, A., Fradi, I., Chiap, P., & Fillet, M. (2006). Enantioseparations in nonaqueous capillary electrophoresis using charged cyclodextrin derivatives as chiral selectors [Paper presentation]. 30th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2006), San Francisco, United States.

Do Thi, T., Pomponi, R., Gotti, R., Saevels, J., Van Hove, B., Van Ael, W., Matthijs, N., Vander Heyden, Y., Marini Djang'Eing'A, R., Chiap, P., Hubert, P., Crommen, J., Fabre, H., Dehouck, P., Hoogmartens, J., & Van Schepdael, A. (2006). Precision study on capillary electrophoresis methods for metacycline. Electrophoresis, 27 (12), 2317-2329. doi:10.1002/elps.200500873

Fillet, M., Fradi, I., Pedrini, M., Chiap, P., Ivanyi, R., Crommen, J., & Servais, A.-C. (2006). Enantioseparation of nonsteroidal anti-inflammatory drugs using single-isomer amino cyclodextrin derivatives in nonaqueous capillary electrophoresis [Poster presentation]. 20th International Symposium on Microscale Bioseparations, Amsterdam, Netherlands.

Marini Djang'Eing'A, R., Chiap, P., Boulanger, B., Rudaz, S., Rozet, E., Crommen, J., & Hubert, P. (2006). LC method for the determination of R-timolol in S-timolol maleate: Validation of its ability to quantify and uncertainty assessment. Talanta, 68 (4), 1166-1175. doi:10.1016/j.talanta.2005.07.026

Marini Djang'Eing'A, R., Chiap, P., Boulanger, B., Rudaz, S., Rozet, E., Crommen, J., & Hubert, P. (2006). Comparaison de trois approches pour l'estimation de l'incertitude. Acta Clinica Belgica. Supplementum, (1), 60-2.

Marini Djang'Eing'A, R., Groom, C., Doucet, F. R., Hawari, J., Bitar, Y., Holzgrabe, U., Gotti, R., Schappler, J., Rudaz, S., Veuthey, J.-L., Mol, R., Somsen, G. W., de Jong, G. J., Ha, P. T. T., Zhang, J., Van Schepdael, A., Hoogmartens, J., Brione, W., Ceccato, A., ... Hubert, P. (2006). Interlaboratory study of a NACE method for the determination of R-timolol content in S-timolol maleate: assessment of uncertainty. Electrophoresis, 27 (12), 2386-99. doi:10.1002/elps.200500832

Marini Djang'Eing'A, R.* , Servais, A.-C.* , Rozet, E., Chiap, P., Boulanger, B., Rudaz, S., Crommen, J., Hubert, P., & Fillet, M. (2006). Nonaqueous capillary electrophoresis method for the enantiomeric purity determination of S-timolol using heptakis(2,3-di-O-methyl-6-O-sulfo)-beta-cyclodextrin: validation using the accuracy profile strategy and estimation of uncertainty. Journal of Chromatography. A, 1120 (1-2), 102-11. doi:10.1016/j.chroma.2006.03.104

Martin, G., Chiap, P., Paquet, P., Pierard, G., Hubert, P., Crommen, J., & Fillet, M. (2006). Determination of catecholamines in human plasma using solid phase extraction and LC-ESI-MS-MS [Poster presentation]. Drug Analysis, Namur, Belgium.

Martin, G., Chiap, P., Paquet, P., Pierard, G., Rozet, E., Hubert, P., Crommen, J., & Fillet, M. (2006). Determination of a melanoma biomarker in human plasma the 5-S-cysteinyl-l-dopa by LC-ESI-MS-MS [Paper presentation]. 30rd international symposium on high performance liquid phase separation and related techniques, San Francisco, United States.

Martin, G., Chiap, P., Pierard, G., Hubert, P., Crommen, J., & Fillet, M. (2006). LC-ESI-MS-MS determination of 5-S-L-cysteinyl-L-dopa, a melanoma biomarker, in human plasma [Poster presentation]. Drug Analysis, Namur, Belgium.

Rousseau, A., Fradi, I., Servais, A.-C., Pedrini, M., Ivanyi, R., Fillet, M., & Crommen, J. (2006). Enantiomeric separation of nonsteroidal anti-inflammatory drugs in nonaqueous capillary electrophoresis using single-isomer amino cyclodextrin derivatives [Poster presentation]. Drug Analysis 2006, Namur, Belgium.

Rozet, E., Boulanger, B., Dewe, W., Chiap, P., Moonen, F., Govaerts, B., Crommen, J., & Hubert, P. (2006). GERER LE RISQUE LORS DE LA VALIDATION DES METHODES ANALYTIQUES : APPLICATION A LA DETERMINATION D’IMPURETES [Paper presentation]. Congrès des Sciences Analytiques, Marrakech, Morocco.

Rozet, E., Dewe, W., Govaerts, B., Boulanger, B., Ceccato, A., Chiap, P., & Crommen, J. (2006). TOWARDS A RISK BASED METHODOLOGY TO ASSESS THE ACCEPTABILITY OF AN ANALYTICAL METHOD TRANSFER: COMPARISON OF DIFFERENT APPROACHES [Poster presentation]. Drug Analysis.

Rozet, E., Morello, R., Dewe, W., Chiap, P., Boulanger, B., Boos, K. S., Crommen, J., & Hubert, P. (2006). TRANSFER OF A MULTIDIMENSIONAL ON-LINE SPE-LC-ECD METHOD FOR THE DETERMINATION OF THREE MAJOR CATECHOLAMINES IN NATIVE HUMAN URINE [Poster presentation]. HPLC.

Servais, A.-C., Fillet, M., Mol, R., Somsen, G., Chiap, P., de Jong, G. J., & Crommen, J. (2006). Determination of salbutamol enantiomers in urine by nonaqueous capillary electrophoresis-mass spectrometry [Poster presentation]. Drug Analysis 2006, Namur, Belgium.

Lecomte, F., Boulanger, B., Hall, A. J., Sellergren, B., Rozet, E., Crommen, J., Chiap, P., & Hubert, P. (September 2005). OPTIMIZATION OF MOLECULARLY IMPRINTED SOLID-PHASE EXTRACTION BY MEANS OF EXPERIMENTAL DESIGN PRIOR TO THE DETERMINATION OF METHOTREXATE IN HUMAN PLASMA [Poster presentation]. RDPA 2005 - 11th International Meeting on Recent Developments in Pharmaceutical Analysis, Rimini, Italy.

Crommen, J., Marini Djang'Eing'A, R., Servais, A.-C., Chiap, P., Rozet, E., Hubert, P., & Fillet, M. (June 2005). Validation of a NACE method for the enantiomeric purity determination of S-timolol using heptakis(2,3-di-O-methyl-6-O-sulfo)-B-CD [Paper presentation]. 29th International Symposium on High Perfomance Liquid Phase Separations and Related Techniques, Stockholm, Sweden.

Lecomte, F., Hall, A. J., Sellegren, B., Crommen, J., Hubert, P., & Chiap, P. (June 2005). Evaluation of molecularly imprinted polymers for selective extraction of methotrexate from human plasma prior to its LC determination [Poster presentation].   HPLC 2005 - 29th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Stockholm, Sweden.

Servais, A.-C., Fillet, M., Chiap, P., Dewé, W., Hubert, P., & Crommen, J. (11 March 2005). Influence of the nature of the electrolyte on the chiral separation of basic compounds in nonaqueous capillary electrophoresis using heptakis(2,3-di-O-methyl-6-O-sulfo)-beta-cyclodextrin. Journal of Chromatography. A, 1068 (1), 143-150. doi:10.1016/j.chroma.2004.12.010

Chiap, P., Piette, M., Evrard, B., Frankenne, F., Christiaens, B., Piel, G., Cataldo, D., Foidart, J.-M., Delattre, L., Crommen, J., & Hubert, P. (05 March 2005). Automated method for the determination of a new matrix metalloproteinase inhibitor in ovine plasma and serum by coupling of restricted access material for on-line sample clean-up to liquid chromatography. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 817 (1), 109-117. doi:10.1016/j.jchromb.2004.08.042

Marini Djang'Eing'A, R., Boulanger, B., Vanderheyden, Y., Chiap, P., Crommen, J., & Hubert, P. (21 February 2005). Uncertainty assessment from robustness testing applied on an LC assay for R-timolol and other related substances in S-timolol maleate. Analytica Chimica Acta, 531 (1), 131-140. doi:10.1016/j.aca.2004.10.004

Rbeida, O., Chiap, P., Lubda, D., Boos, K. S., Crommen, J., & Hubert, P. (04 January 2005). Development and validation of a fully automated LC method for the determination of cloxacillin in human plasma using anion exchancre restricted access material for sample clean-up. Journal of Pharmaceutical and Biomedical Analysis, 36 (5), 961-968. doi:10.1016/j.jpba.2004.09.017

Rbeida, O., Christiaens, B., Hubert, P., Lubda, D., Boos, K. S., Crommen, J., & Chiap, P. (04 January 2005). Integrated on-line sample clean-up using cation exchange restricted access sorbent for the LC determination of atropine in human plasma coupled to UV detection. Journal of Pharmaceutical and Biomedical Analysis, 36 (5), 947-954. doi:10.1016/j.jpba.2004.08.007

Chiap, P., Boulanger, B., Dewé, W., Crommen, J., & Hubert, P. (2005). Recent trends in the validation of bioanalytical methods [Paper presentation]. PharmSciFair, Nice, France.

Chiap, P., Rbeida, O., Boos, K. S., Hubert, P., & Crommen, J. (2005). Recent developments in on-line coupling of SPE to LC using restricted access materials with different functionalities [Paper presentation]. International seminar on solid-phase extraction in clinical and biopharmaceutical samples, Maastricht, Netherlands.

Chiap, P., Rbeida, O., Lubda, D., Boos, K. S., Crommen, J., & Hubert, P. (2005). Development and validation of a LC method for the determination of cloxacillin in plasma using anion exchange restricted access material for on-line sample clean-up [Poster presentation]. 29th international symposium on high performance liquid phase separations and related techniques, Stockholm, Sweden.

Crommen, J., Servais, A.-C., Fradi, I., Chiap, P., & Fillet, M. (2005). Enantioselective determination of pharmaceutical compounds in biofluids by coupling SPE to non-aqueous CE with charged cyclodextrins as chiral additives [Paper presentation]. 4th International Symposium on Separations in the BioSciences (SBS’05), Utrecht, Netherlands.

Crommen, J., Servais, A.-C., Fradi, I., Fillet, M., & Chiap, P. (2005). Enantioseparation of ionizable compounds in non-aqueous capillary electrophoresis using charged cyclodextrin derivatives as chiral additives [Paper presentation]. 29th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2005), Stockholm, Sweden.

Crommen, J., Servais, A.-C., Fradi, I., Marini Djang'Eing'A, R., Chiap, P., Hubert, P., & Fillet, M. (2005). Enantiomeric separation of acidic and basic chiral drugs in non-aqueous capillary electrophoresis using cyclodextrin with the opposite charge [Paper presentation]. 11th meeting on recent developments in pharmaceutical analysis (RDPA), Rimini, Italy.

Hans, G., Malgrange, B., Lallemend, F., Crommen, J., Wislet-Gendebien, S., Belachew, S., Robe, P., Rogister, B., Moonen, G., & Rigo, J.-M. (January 2005). beta-carbolines induce apoptosis in cultured cerebellar granule neurons via the mitochondrial pathway. Neuropharmacology, 48 (1), 105-117. doi:10.1016/j.neuropharm.2004.09.001

Marini Djang'Eing'A, R., Matthijs, N., Vanderheyden, Y., Smeyers-Verbeke, J., Dehouck, P., Hoogmartens, J., Silvestre, P., Ceccato, A., Goedert, P., Saevels, J., Herbots, C., Caliaro, G., Herraez-Hernandez, R., Verdu-Andres, J., Campins-falco, P., de Wauw, W. V., De Beer, J., Boulanger, B., Chiap, P., ... Hubert, P. (2005). Collaborative study of an liquid chromatographic method for the determination of R-timolol and other related substances in S-timolol maleate. Analytica Chimica Acta, 546 (2), 182-192. doi:10.1016/j.aca.2005.05.026

Martin, G., Chiap, P., Paquet, P., Pierard, G., Hubert, P., & Crommen, J. (2005). Determination of catecholamines in human plasma using solid phase extraction and LC-ESI-MS-MS [Poster presentation]. 29th international symposium on high performance liquid phase separations and related techniques, Stockholm, Sweden.

Mol, R., Servais, A.-C., Fillet, M., Crommen, J., De Jong, G. J., & Somsen, G. W. (2005). Coupling of non-aqueous electrokinetic chromatography to electrospray ionization mass spectrometry (NAEKC-ESI-MS) for drug analysis [Poster presentation]. 4th International Symposium on Separations in the BioSciences (SBS’05), Utrecht, Netherlands.

Rozet, E., Chiap, P., Dewe, W., Boulanger, B., Crommen, J., & Hubert, P. (2005). The Usefulness of Accuracy Profile to Validate Analytical Methods [Paper presentation]. RDPA - Recent Developement in Pharmaceutical Analysis.

Rozet, E., Mertens, B., Dewe, W., Govaerts, B., Boulanger, B., Chiap, P., Streel, B., Crommen, J., & Hubert, P. (2005). USING TOTAL ERROR AS DECISION CRITERION IN METHOD TRANSFER [Poster presentation]. RDPA-Recent Development on Pharmaceutical Analysis.

Dewé, W., Marini Djang'Eing'A, R., Chiap, P., Hubert, P., Crommen, J., & Boulanger, B. (28 December 2004). Development of response models for optimising HPLC methods. Chemometrics and Intelligent Laboratory Systems, 74 (2), 263-268. doi:10.1016/j.chemolab.2004.04.016

Christiaens, B., Fillet, M., Chiap, P., Rbeida, O., Ceccato, A., Streel, B., De Graeve, J., Crommen, J., & Hubert, P. (12 November 2004). Fully automated method for the liquid chromatographic-tandem mass spectrometric determination of cyproterone acetate in human plasma using restricted access material for on-line sample clean-up. Journal of Chromatography. A, 1056 (1-2), 105-110. doi:10.1016/j.chroma.2004.06.107

Henry de Hassonville, S., Chiap, P., Liégeois, J.-F., Evrard, B., Delattre, L., Crommen, J., Piel, G., & Hubert, P. (21 September 2004). Development and validation of a high-performance liquid chromatographic method for the determination of cyproterone acetate in human skin. Journal of Pharmaceutical and Biomedical Analysis, 36 (1), 133-143. doi:10.1016/j.jpba.2004.05.023

Servais, A.-C., Fillet, M., Chiap, P., Dewé, W., Hubert, P., & Crommen, J. (August 2004). Enantiomeric separation of basic compounds usin heptakis(2,3-di-O-methyl-6-O-sulfo)-beta-cyclodextrin in combination with potassium camphorsulfonate in nonaqueous capillary electrophoresis: Optimization by means of an experimental design. Electrophoresis, 25 (16), 2701-2710. doi:10.1002/elps.200405962

Van Eeckhaut, A., Detaevernier, M. R., Crommen, J., & Michotte, Y. (August 2004). Influence of methanol on the enantioresolution of antihistamines with carboxymethyl-beta-cyclodextrin in capillary electrophoresis. Electrophoresis, 25 (16), 2838-2847. doi:10.1002/elps.200406021

Servais, A.-C., Chiap, P., Hubert, P., Crommen, J., & Fillet, M. (June 2004). Determination of salbutamol enantiomers in human urine using heptakis(2,3-di-O-acetyl-6-O-sulfo)-beta-cyclodextrin in nonaqueous capillary electrophoresis. Electrophoresis, 25 (10-11), 1632-1640. doi:10.1002/elps.200405854

Henry de Hassonville, S., Christiaens, B., Piel, G., Barillaro, V., Bertholet, P., Chiap, P., Hubert, P., Crommen, J., Delattre, L., Pierard, G., & Evrard, B. (May 2004). Effect of methylated-b-cyclodextrin on the skin and influence on cyproterone acetate percutaneous absorption [Poster presentation]. XII th International Cyclodextrin Symposium, Montpellier, France.

Rbeida, O., Christiaens, B., Hubert, P., Lubda, D., Boos, K. S., Crommen, J., & Chiap, P. (19 March 2004). Evaluation of a novel anion-exchange restricted-access sorbent for on-line sample clean-up prior to the determination of acidic compounds in plasma by liquid chromatography. Journal of Chromatography. A, 1030 (1-2), 95-102. doi:10.1016/j.chroma.2003.11.031

Marini Djang'Eing'A, R., Boulanger, B., Abushoffa, A., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (February 2004). ENANTIOMERIC PURITY TESTING OF S-KETOPROFEN IN PHARMACEUTICAL FORMULATIONS BY CE USING A DUAL CYCLODEXTRIN SYSTEM [Poster presentation]. 17th International Symposium on Microscale Separations and Capillary Electrophoresis, Salzburg, Austria.

Bimazubute, M., Chiap, P., Janssen, L., Gustin, P., Crommen, J., & Hubert, P. (2004). Automated determination of oxytetracycline in plasma of healthy pigs by at-line coupling of solid phase extraction to liquid chromatography [Poster presentation]. 15th international symposium on pharmaceutical and biomedical analysis, Florence, Italy.

Chiap, P., Dewé, W., Boulanger, B., Crommen, J., & Hubert, P. (2004). Use of accuracy profiles as efficient decision tool for the validation of quantitative analytical methods [Poster presentation]. 15th international symposium on pharmaceutical and biomedical analysis, Florence, Italy.

Chiap, P., Rbeida, O., Christiaens, B., Hubert, P., Lubda, D., Boos, K. S., & Crommen, J. (2004). Evaluation of novel restricted access sorbents with ion exchange properties for on-line sample clean-up prior to the LC determination of acidic of basic compounds in plasma [Poster presentation]. 15th international symposium on pharmaceutical and biomedical analysis, Florence, Italy.

Christiaens, G., Chiap, P., Fillet, M., Rbeida, O., Ceccato, A., Streel, B., De Graeve, J., Crommen, J., & Hubert, P. (2004). New fully automated method for the LC-MS/MS determination of cyproterone acetate in human plasma using restricted access material for sample clean-up [Poster presentation]. 8th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers (HTC-8), Bruges, Belgium.

Christians, B., Fillet, M., Chiap, P., Rbeida, O., Ceccato, A., Streel, B., De Graeve, J., Crommen, J., & Hubert, P. (2004). Fully automated method for the liquid chromatographic-tandem mass spectrometric determination of cyproterone acetate in human plasma using restricted access material for on-line sample clean-up. Journal of Chromatography. A, 1056 (1-2), 105-10.

Crommen, J., Rbeida, O., Chiap, P., Christiaens, B., Lubda, D., & Hubert, P. (2004). Evaluation de nouvelles phases à accès restreint échangeuses d’ions pour l’extraction sélective de comosoés médicamenteux dans le plasma avant leur analyse chromatographique [Poster presentation]. Forum labo et forum biotech, Paris, France.

Crommen, J., Servais, A.-C., Fillet, M., Chiap, P., Dewé, W., & Hubert, P. (2004). Enantiomeric separation of ionisable compounds in non-aqueous capillary electrophoresis using charged cyclodextrins in combination with ion-pairing reagents [Paper presentation]. 25th International Symposium on Chromatography (ISC 04), Paris, France.

Crommen, J., Servais, A.-C., Fillet, M., Chiap, P., Dewé, W., & Hubert, P. (2004). Enantiomeric separation of basic drugs using anionic cyclodextrins in non-aqueous capillary electrophoresis : optimization of the background electrolyte composition [Paper presentation]. 17th International Symposium on Microscale Separations an Capillary Electro-phoresis, Salzburg, Austria.

Crommen, J., Servais, A.-C., Fillet, M., Chiap, P., & Hubert, P. (2004). Enantiomeric separation in non-aqueous capillary electrophoresis using charged cyclodextrins in combination with other ionic additives [Paper presentation]. 15th International Symposium on pharmaceutical and biomedical analysis (PBA), Florence, Italy.

Crommen, J., Servais, A.-C., Fillet, M., & Hubert, P. (2004). Enantioseparation of basic pharmaceuticals in non-aqueous capillary electrophoresis using anionic cyclodextrins as chiral selectors [Paper presentation]. 12th International Cyclodextrin Symposium, Montpellier, France.

Henry de Hassonville, S., Christiaens, B., Piel, G., Barillaro, V., Bertholet, P., Chiap, P., Hubert, P., Crommen, J., Delattre, L., Pierard, G., & Evrard, B. (2004). La Rameb, un promoteur d’absorption cutanée pour l’acétate de cypro-térone ? [Paper presentation]. 7e journées du club cyclodextrines, Lille, France.

Herchuelz, A., Carreer-Bruhwyler, F., Crommen, J., Chiap, P., Hubert, P., Messin, R., Dubois, C., Famaey, J.-P., & Géczy, J. (2004). Clinical pharmacokinetics of once-daily molsidomine - From immediate-release to prolonged-release once-daily formulations. American Journal of Drug Delivery, 2 (2), 131-141. doi:10.2165/00137696-200402020-00005

Hubert, P., Boulanger, B., Dewé, W., Chiap, P., & Crommen, J. (2004). Harmonisation des stratégies de validation, utopie ou réalité ? [Paper presentation]. Forum labo et forum biotech, Paris, France.

Hubert, P., Chiap, P., Dormal, C., Crommen, J., Dewé, W., & Boulanger, B. (2004). Intérêt du profil d'exactitude dans le cadre de la validation des méthodes analytiques [Poster presentation]. Forum labo et Forum biotech, Paris, France.

Jaspart, S., Kirschvink, N., Chiap, P., Delattre, L., Crommen, J., Gustin, P., & Evrard, B. (2004). Solid lipid Nanoparticles for administration by inhalation : Optimisation of manufacturing parameters and preliminary tolerance study [Paper presentation]. 12eme Forum des Sciences Pharmaceutiques, Blankenberge, Belgium.

Servais, A.-C., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (2004). Validation d’une méthode de dosage des énantiomères du salbutamol dans l’urine par électrophorèse capillaire en milieu non aqueux en utilisant une cyclodextrine anionique comme sélecteur chiral [Poster presentation]. Forum labo et forum biotech, Paris, France.

Servais, A.-C., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (2004). First application of non-aqueous capillary electrophoresis for the determination of the enantiomers of a basic chiral drug in biological samples: Quantification of salbutamol in human urine [Poster presentation]. 15th International Symposium on pharmaceutical and biomedical analysis (PBA), Florence, Italy.

Servais, A.-C., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (2004). Determination of salbutamol enantiomers in human urine using anionic cyclo-dextrins in non-aqueous capillary electrophoresis [Poster presentation]. 17th International Symposium on Microscale Separations an Capillary Electro-phoresis, Salzburg, Austria.

Christiaens, B., Chiap, P., Rbeida, O., Cello, D., Crommen, J., & Hubert, P. (25 September 2003). Fully automated method for the liquid chromatographic determination of cyproterone acetate in plasma using restricted access material for sample pre-treatment. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 795 (1), 73-82. doi:10.1016/S1570-0232(03)00517-8

Boulanger, B., Chiap, P., Dewé, W., Crommen, J., & Hubert, P. (08 August 2003). An analysis of the SFSTP guide on validation of chromatographic bioanalytical methods: progresses and limitations. Journal of Pharmaceutical and Biomedical Analysis, 32 (4-5), 753-765. doi:10.1016/S0731-7085(03)00182-1

Rbeida, O., Christiaens, B., Chiap, P., Hubert, P., Lubda, D., Boos, K. S., & Crommen, J. (08 August 2003). Fully automated LC method for the determination of sotalol in human plasma using restricted access material with cation exchange properties for sample clean-up. Journal of Pharmaceutical and Biomedical Analysis, 32 (4-5), 829-838. doi:10.1016/S0731-7085(03)00186-9

Marini Djang'Eing'A, R., Chiap, P., Boulanger, B., Dewé, W., Hubert, P., & Crommen, J. (July 2003). LC method for the simultaneous determination of R-timolol and other closely related impurities in S-timolol maleate: Optimization by use of an experimental design. Journal of Separation Science, 26 (9-10), 809-817. doi:10.1002/jssc.200301367

Messin, R., Fenyvesi, T., Carreer-Bruhwyler, F., Crommen, J., Chiap, P., Hubert, P., Dubois, C., Famaey, J. P., & Geczy, J. (July 2003). A pilot double-blind randomized placebo-controlled study of molsidomine 16 mg once-a-day in patients suffering from stable angina pectoris: correlation between efficacy and over time plasma concentrations. European Journal of Clinical Pharmacology, 59 (3), 227-232. doi:10.1007/s00228-003-0597-z

Dehouck, P., Vander Heyden, Y., Smeyers-Verbecke, J., Massart, D. L., Marini Djang'Eing'A, R., Chiap, P., Hubert, P., Crommen, J., Van de Wauw, De Beer, Cox, R., Reepmeyer, Voigt, B., Estevenon, O., Nicolas, A., Van Schepdael, A., Adams, E., Hoogmartens, J., & Mathieu, G. (May 2003). Determination of uncertainty in a liquid chromatographic method for erythromycin from Interlaboratory study results [Paper presentation]. 11th Forum of the Belgian Society of Pharmaceutical Sciences (SBSP 2003), Spa, Belgium.

Fillet, M., Servais, A.-C., & Crommen, J. (May 2003). Effects of background electrolyte composition and addition of selectors on separation selectivity in nonaqueous capillary electrophoresis. Electrophoresis, 24 (10), 1499-1507. doi:10.1002/elps.200305412

Marini Djang'Eing'A, R., Chiap, P., Boulanger, B., Hubert, P., & Crommen, J. (May 2003). ASSESSMENT OF UNCERTAINTY FROM ROBUSTNESS TESTING OF A LC METHOD FOR THE DETERMINATION OF R-TIMOLOL AND OTHER RELATED SUBSTANCES IN S-TIMOLOL MALEATE [Paper presentation]. 11th Forum of the Pharmaceutical Sciences, Spa, Belgium.

Piette, V., Lammerhofer, M., Lindner, W., & Crommen, J. (14 February 2003). Enantiomer separation of N-protected amino acids by non-aqueous capillary electrophoresis and high-performance liquid chromatography with tert.-butyl carbamoylated quinine in either the background electrolyte or the stationary phase. Journal of Chromatography. A, 987 (1-2), 421-427. doi:10.1016/S0021-9673(02)01465-6

Dehouck, P., Vander Heyden, Y., Smeyers-Verbeke, J., Massart, D. L., Crommen, J., Hubert, P., Marini Djang'Eing'A, R., Smeets, O. S. N. M., Decristoforo, G., Van de Wauw, W., De Beer, J., Quaglia, M. G., Stella, C., Veuthey, J.-L., Estevenon, O., Van Schepdael, A., Roets, E., & Hoogmartens, J. (17 January 2003). Determination of uncertainty in analytical measurements from collaborative study results on the analysis of a phenoxymethylpenicillin sample. Analytica Chimica Acta, 481, 261-272. doi:10.1016/S0003-2670(03)00079-5

Abushoffa, A. M., Fillet, M., Marini Djang'Eing'A, R., Hubert, P., & Crommen, J. (2003). Enantiomeric separation of aminoglutethimide by capillary electrophoresis using native cyclodextrins in single and dual systems. Journal of Separation Science, 26 (6-7), 536-542. doi:10.1002/jssc.200390073

Abushoffa, A. M., Fillet, M., Servais, A.-C., Hubert, P., & Crommen, J. (2003). Enhancement of selectivity and resolution in the enantioseparation of uncharged compounds using mixtures of oppositely charged cyclodextrins in capillary electrophoresis. Electrophoresis, 24 (3), 343-50. doi:10.1002/elps.200390044

Boulanger, B., Dewé, W., Chiap, P., Crommen, J., & Hubert, P. (2003). Objectives of analytical methods and objectives of validation [Paper presentation]. Landolake conference, Wisconsin, United States.

Boulanger, B., Marini Djang'Eing'A, R., Chiap, P., Dewé, W., Crommen, J., & Hubert, P. (2003). Objectives of analytical methods and objectives of validation : how to reconciliate them ? [Paper presentation]. HPLC 2003, 27th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Nice, France.

Chiap, P., Crommen, J., Dormal, C., Dewé, W., Boulanger, B., & Hubert, P. (2003). Intérêt du profil d’exactitude dans le cadre de la validation d’une méthode de dosage par chromatographie liquide du miconazole, de l’éconazole et du sor-bate dans les préparations à usage dermatologie [Poster presentation]. 5E Congrès francophone sur les techniques séparatives et les couplages (SEP 2003), Lyon, France.

Crommen, J., Servais, A.-C., Dewé, W., Chiap, P., Fillet, M., & Hubert, P. (2003). Enantiomeric separation of basic pharmaceuticals in non-aqueous capillary electrophoresis using an anionic cyclodextrin in combination with an ion-pairing reagent [Paper presentation]. 3th International Symposium on Separations in Biosciences (SBS 2003), Moscow, Russia.

Crommen, J., Servais, A.-C., Fillet, M., Abushoffa, A., Chiap, P., & Hubert, P. (2003). Modulation of selectivity for the enantiomeric separation of basic compounds in non-aqueous CE using anionic cyclodextrins in combination with ion-pairing re-agents [Paper presentation]. 27th International Symposium on high performance liquid phase separations and related techniques, Nice, France.

Crommen, J., Servais, A.-C., Fillet, M., & Hubert, P. (2003). New approaches for enantiomeric separation in non-aqueous camillary electrophoresis (NACE) [Paper presentation]. 4th International Symposium on Pharmaceutical Chemistry, Istanbul, Turkey.

Dehouck, P., Vander Heyden, Y., Smeyers-Verbeke, J., Massart, D. L., Marini Djang'Eing'A, R., Chiap, P., Hubert, P., Crommen, J., Van de Wauw, W., De Beer, J., Cox, R., Mathieu, G., Reepmeyer, J. C., Voigt, B., Estevenon, O., Nicolas, A., Van Schepdael, A., Adams, E., & Hoogmartens, J. (2003). Interlaboratory study of a liquid chromatography method for erythromycin: determination of uncertainty. Journal of Chromatography. A, 1010 (1), 63-74. doi:10.1016/S0021-9673(03)01023-9

Dewé, W., Marini Djang'Eing'A, R., Chiap, P., Hubert, P., Crommen, J., & Boulanger, B. (2003). Development of response models for optimising HPLC methods [Poster presentation]. HPLC ‘03, 27th International Symposium on High Performance Liquid Phase Separations an Related Techniques, Nice, France.

Henry de Hassonville, S., Christiaens, B., Piel, G., Barillaro, V., Bertholet, P., Chiap, P., Hubert, P., Crommen, J., Delattre, L., Pierard, G., & Evrard, B. (2003). Cyclodextrins as topical permeation enhancers : in vitro and in vivo testing [Poster presentation]. Symposium skin and formulation APGI, Paris, France.

Hubert, P., Chiap, P., Dewé, W., Boulanger, B., & Crommen, J. (2003). Harmonization of validation strategies for analytical methods [Paper presentation]. 4th international symposium on pharmaceutical chemistry, Istanbul, Turkey.

Hubert, P., Chiap, P., Laurentie, M., Dewé, W., Boulanger, B., & Crommen, J. (2003). Harmonisation des démarches de validation, est-elle possible ? [Paper presentation]. 5E Congrès francophone sur les techniques séparatives et les couplages (SEP 2003), Lyon, France.

Martin, Y., Reynders, V., Chiap, P., Dormal, C., Hubert, P., & Crommen, J. (2003). Intérêt du profil d’exactitude dans le cadre de la validation d’une méthode de dosage par chromatographie liquide du miconazole, de l’éconazole et du sor-bate dans les préparations à usage dermatologie [Poster presentation]. 5E Congrès francophone sur les techniques séparatives et les couplages (SEP 2003), Lyon, France.

Servais, A.-C., Dewé, W., Chiap, P., Fillet, M., Abushoffa, A., Hubert, P., & Crommen, J. (2003). Separation énatiomérique de substances médicamenteuses basiques par électrophorèse capillarie en milieu non aqueux : effet de l’utilisation simul-tanée d’une cyclodextrine anionique et d’un agent d’appariement d’ions [Paper presentation]. 5e Congrès francophone sur les techniques séparatives et les couplages (SEP 2003), Lyon, France.

Servais, A.-C., Fillet, M., Abushoffa, A. M., Hubert, P., & Crommen, J. (2003). Synergistic effects of ion-pairing in the enantiomeric separation of basic compounds with cyclodextrin derivatives in nonaqueous capillary electrophoresis. Electrophoresis, 24 (3), 363-369. doi:10.1002/elps.200390046

Evrard, B., Chiap, P., De Tullio, P., Ghalmi, F., Piel, G., Van Hees, T., Crommen, J., Losson, B., & Delattre, L. (13 December 2002). Oral bioavailability in sheep of albendazole from a suspension and from a solution containing hydroxypropyl-beta-cyclodextrin. Journal of Controlled Release, 85 (1-3), 45-50. doi:10.1016/S0168-3659(02)00270-5

Servais, A.-C., Fillet, M., Chiap, P., Abushoffa, A. M., Hubert, P., & Crommen, J. (December 2002). Optimization of the separation of beta-blockers by ion-pair capillary electrophoresis in non-aqueous media using univariate and multivariate approaches. Journal of Separation Science, 25 (15-17), 1087-1095. doi:10.1002/1615-9314(20021101)25:15/17<1087::AID-JSSC1087>3.0.CO;2-A

Chiap, P., Rbeida, O., Christiaens, B., Hubert, P., Lubda, D., Boos, K. S., & Crommen, J. (25 October 2002). Use of a novel cation-exchange restricted-access material for automated sample clean-up prior to the determination of basic drugs in plasma by liquid chromatography. Journal of Chromatography. A, 975 (1), 145-155. doi:10.1016/S0021-9673(02)01334-1

Marini Djang'Eing'A, R., Chiap, P., Boulanger, B., Dewé, W., Hubert, P., & Crommen, J. (April 2002). DEVELOPMENT AND VALIDATION OF A SIMULTANEOUS LC METHOD FOR THE DETERMINATION OF S-TIMOLOL MALEATE, ITS ANTIPODE AND RELATED SUBSTANCES USING A CELLULOSE BASED CHIRAL STATIONARY PHASE [Poster presentation]. Drug Analysis 2002 Symposium, Bruges, Belgium.

Chiap, P., Hubert, P., & Crommen, J. (01 March 2002). Strategy for the development of automated methods involving dialysis and trace enrichment as on-line sample preparation for the determination of basic drugs in plasma by liquid chromatography. Journal of Chromatography. A, 948 (1-2), 151-161. doi:10.1016/S0021-9673(01)01318-8

Marini Djang'Eing'A, R., Pantella, A., Bimazubute, M., Chiap, P., Hubert, P., & Crommen, J. (March 2002). Optimisation and validation of a generic method for the LC assay of six corticosteroids and salicylic acid in dermopharmaceutical forms. Chromatographia, 55 (5-6), 263-269. doi:10.1007/BF02491657

Piette, V., Lindner, W., & Crommen, J. (01 March 2002). Enantiomeric separation of N-protected amino acids by non-aqueous capillary electrophoresis with dimeric forms of quinine and quinidine derivatives serving as chiral selectors. Journal of Chromatography. A, 948 (1-2), 295-302. doi:10.1016/S0021-9673(01)01591-6

Chankvetadze, B., & Crommen, J. (15 January 2002). The impact of enantioseparation techniques on the development and use of chiral drugs - Preface. Journal of Pharmaceutical and Biomedical Analysis, 27 (3-4), 355-355. doi:10.1016/S0731-7085(01)00645-8

Chiap, P., Ceccato, A., Gora, R., Hubert, P., Geczy, J., & Crommen, J. (15 January 2002). Automated determination of pirlindole enantiomers in plasma by on-line coupling of a pre-column packed with restricted access material to a chiral liquid chromatographic column. Journal of Pharmaceutical and Biomedical Analysis, 27 (3-4), 447-455. doi:10.1016/S0731-7085(01)00647-1

Abushoffa, A. M., Burjanadze, N., Blaschke, G., Crommen, J., & Chankvetadze, B. (January 2002). Comparative study on the enantioseparation of glutethimide using dual cyclodextrin systems and cyclodextrin modified MEKC in capillary electrophoresis. Journal of Separation Science, 25 (1-2), 10-16. doi:10.1002/1615-9314(20020101)25:1/2<10::AID-JSSC10>3.0.CO;2-K

Abushoffa, A., Fillet, M., Hubert, P., & Crommen, J. (2002). Selectivity enhancement for the CE enantioseparation of uncharged compounds using mixtures of cationic and anionic cyclodextrin derivatives [Poster presentation]. 15th International Symposium on Microscale Separations and Analyses (HPCE 2002), Stockholm, Sweden.

Abushoffa, A. M., Fillet, M., Hubert, P., & Crommen, J. (2002). Prediction of selectivity for enantiomeric separations of uncharged compounds by capillary electrophoresis involving dual cyclodextrin systems. Journal of Chromatography. A, 948 (1-2), 321-9. doi:10.1016/S0021-9673(01)01371-1

Abushoffa, A., Fillet, M., Servais, A.-C., Hubert, P., & Crommen, J. (2002). Enantioseparation of uncharged compounds using combinations of octakis-(2,3-dihydroxy-6-sulfato)--cyclodextrin and heptakis-(2,3,6-tri-O-methyl)--cyclodextrin in capillary electrophoresis [Poster presentation]. 26th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2002), Montreal, Canada.

Boulanger, B., Dewé, W., Chiap, P., Crommen, J., & Hubert, P. (2002). Objectives and analytical methods and objectives of validation [Paper presentation]. Barnett Conference, Philadelphie, United States.

Boulanger, B., Dewé, W., Chiap, P., Crommen, J., & Hubert, P. (2002). Objectifs des méthodes analytiques et objectifs de la validation. Comment les réconcilier pour garantir la qualité des résultats ? [Paper presentation]. Chimiométrie, Paris, France.

Chiap, P., Rbeida, O., Christiaens, B., Hubert, P., Lubda, D., Boos, K. S., & Crommen, J. (2002). Evaluation of a new kind of cation exchange restricted access sorbent for on-line solid phase extraction of basic drugs from plasma prior to their determination by liquid chromatography [Poster presentation]. 7th International Symposium on Drug Analysis, Bruges, Belgium.

Christiaens, B., Cello, D., Chiap, P., Rbeida, O., Hubert, P., & Crommen, J. (2002). Fully automated method for the liquid chromatographic determination of cyproterone acetate in plasma using restricted access material for sample pre-treatment [Poster presentation]. 7th International Symposium on Drug Analysis, Bruges, Belgium.

Crommen, J., Abushoffa, A., Fillet, M., & Hubert, P. (2002). The design of dual systems for amplification of selectivity in CE enantioseparations [Paper presentation]. 15th International Symposium on Microscale Separations and Analyses (HPCE 2002), Stockholm, Sweden.

Crommen, J., Servais, A.-C., Abushoffa, A., Fillet, M., & Hubert, P. (2002). Selectivity enhancement in chiral and achiral separations of basic drugs by ion-pairing in non-aqueous capillary electrophoresis [Paper presentation]. 26th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2002), Montreal, Canada.

Fillet, M., Servais, A.-C., Van Heugen, J.-C., De Graeve, J., & Crommen, J. (2002). Identification and quantification of endogenous ceramides in human cancer cells by LC-ESI-MS-MS [Poster presentation]. 7th International Symposium on Drug Analysis, Bruges, Belgium.

Fillet, M., Van Heugen, J.-C., Servais, A.-C., De Graeve, J., & Crommen, J. (2002). Separation, identification and quantitation of ceramides in human cancer cells by liquid chromatography–electrospray ionization tandem mass spectrometry. Journal of Chromatography. A, 949, 225-233. doi:10.1016/S0021-9673(01)01422-4

Hubert, P., Chiap, P., Dormal, C., Boulanger, B., Dewé, W., & Crommen, J. (2002). Intérêt du profil d'exactitude dans le cadre de la validation des méthodes analytiques [Paper presentation]. Forum Labo, Paris, France.

Hubert, P., Chiap, P., Dormal, C., Crommen, J., Dewé, W., & Boulanger, B. (2002). Intérêt du profil d’exactitude dans le cadre de la validation des méthodes ana-lytiques [Paper presentation]. Club chimiométrie et assurance qualité, INRA, Paris, France.

Hubert, P., Chiap, P., Dormal, C., Dewé, W., Boulanger, B., & Crommen, J. (2002). Statistical analysis of the validation results: diagnostic or decision tools [Paper presentation]. 7th International Symposium on Drug Analysis, Bruges, Belgium.

Rbeida, O., Christiaens, B., Chiap, P., Hubert, P., Lubda, D., Boos, K. S., & Crommen, J. (2002). The use of a novel cation exchange restricted access material for automated sample clean-up prior to the determination of basic drugs in plasma by liquid chromatography [Poster presentation]. 7th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers (HTC 7), Bruges, Belgium.

Servais, A.-C., Fillet, M., Chiap, P., Abushoffa, A., Hubert, P., & Crommen, J. (2002). Multivariate optimization approach for the separation of beta-blockers by ion-pair capillary electrophoresis in non-aqueous media [Poster presentation]. 7th International Symposium on Drug Analysis, Bruges, Belgium.

Marini Djang'Eing'A, R., Chiap, P., Hubert, P., & Crommen, J. (June 2001). SIMULTANEOUS LC DETERMINATION OF R-TIMOLOL MALEATE AND OTHER CLOSELY RELATED IMPURITIES IN S-TIMOLOL MALEATE USING A CELLULOSE BASED CHIRAL STATIONARY PHASE [Poster presentation]. 25th International Symposium on High Performance Liquid Phase Separations andr Related Technique, Maastricht, Netherlands.

Marini Djang'Eing'A, R., Chiap, P., Hubert, P., & Crommen, J. (25 May 2001). Separation and simultaneous determination of S-timolol maleate, its optical antipode and related substances by liquid chromatography using a cellulose based chiral stationary phase [Paper presentation]. 10th Forum of Pharmaceutical Sciences, Montréal, Canada.

Toussaint, B., Palmer, M., Chiap, P., Hubert, P., & Crommen, J. (April 2001). On-Line Coupling of Partial Filling-Capillary Zone Electrophoresis with Mass Spectrometry for the Separation of Clenbuterol Enantiomers. Electrophoresis, 22 (7), 1363-72. doi:10.1002/1522-2683(200105)22:7<1363::AID-ELPS1363>3.0.CO;2-Q

Chiap, P., Ceccato, A., Miralles Buraglia, B., Boulanger, B., Hubert, P., & Crommen, J. (March 2001). Development and Validation of an Automated Method for the Liquid Chromatographic Determination of Sotalol in Plasma Using Dialysis and Trace Enrichment on a Cation-Exchange Pre-Column as on-Line Sample Preparation. Journal of Pharmaceutical and Biomedical Analysis, 24 (5-6), 801-14. doi:10.1016/S0731-7085(00)00547-1

Abushoffa, A., Fillet, M., Hubert, P., & Crommen, J. (2001). Prediction of selectivity and resolution in enatiomeric separations of uncharged compounds by capillary electrophoresis using dual cyclodextrin systems [Poster presentation]. HPCE 2001, Boston, United States.

Abushoffa, A., Fillet, M., Hubert, P., & Crommen, J. (2001). CE determination of binding constants between profen enantiomers and single-isomer anionic and neutral cyclodextrins [Poster presentation]. HPLC 2001, Maastricht, Netherlands.

Chiap, P., Boulanger, B., Fotsing, L., Hubert, P., & Crommen, J. (2001). Liquid chromatographic analysis of local anesthetics in human plasma after sample preparation by on-line dialysis. Optimization by use of experimental design. Chromatographia, 53 (11-12), 678-686. doi:10.1007/BF02493020

Chiap, P., Hubert, P., & Crommen, J. (2001). Strategy for the development of automated methods using dialysis and trace enrichment as on-line sample preparation techniques for the LC determination of drugs in plasma [Poster presentation]. HPLC 2001, Maastricht, Netherlands.

Crommen, J., Abushoffa, A., Fillet, M., Chankvetadze, B., & Hubert, P. (2001). The use of two chiral selectors in combination for the enantioseparation of drugs by capillary electrophoresis : benefits and limitations [Paper presentation]. 9th International Meeting on Recent Developments in Pharmaceutical Analysis (RDPA) 2001, Lipari, Aeolian Islands, Messina, Italy.

Crommen, J., Abushoffa, A., Fillet, M., & Hubert, P. (2001). Prédiction de la sélectivité lors de séparations chirales en électrophorèse capillaire à l’aide de mélanges de cyclodextrines (systèmes duaux) [Paper presentation]. SEP 2001, Paris, France.

Crommen, J., Abushoffa, A., Fillet, M., & Hubert, P. (2001). Optimization of the CE enantioseparation of uncharged compounds in dual cyclodextrin systems [Paper presentation]. HPCE 2001, Boston, United States.

Crommen, J., Abushoffa, A., Fillet, M., & Hubert, P. (2001). Modulation of selectivity for enantiomeric separation in CE using mixtures of cationic and anionic cyclodextrins [Paper presentation]. HPLC 2001, Maastricht, Netherlands.

Hubert, P., Boulanger, B., Chiap, P., Dewé, W., & Crommen, J. (2001). Développements récents dans le domaine de la validation de méthodes en analyse pharmaceutique et biomédicale [Paper presentation]. SEP 2001, Paris, France.

Hubert, P., Chiap, P., Dewé, W., Boulanger, B., & Crommen, J. (2001). The usefulness of accuracy profiles in LC method validation [Paper presentation]. HPLC 2001, Maastricht, Netherlands.

Rbeida, O., Christiaens, B., Chiap, P., Hubert, P., & Crommen, J. (2001). A novel cation exchange restricted access material for precolumns in the LC analysis of basic drugs in plasma using the column switching technique [Poster presentation]. HPLC 2001, Maastricht, Netherlands.

Servais, A.-C., Fillet, M., Hubert, P., & Crommen, J. (2001). Separation of closely related basic drugs by ion-pair capillary electrophoresis in non-aqueous media [Paper presentation]. Forum des Sciences Pharmaceutiques, Montréal, Canada.

Servais, A.-C., Fillet, M., Hubert, P., & Crommen, J. (2001). Separation of beta-blockers by ion-pair capillary electrophoresis in non-aqueous media [Poster presentation]. HPLC 2001, Maastricht, Netherlands.

Toussaint, B., Pitti, C., Streel, B., Ceccato, A., Hubert, P., & Crommen, J. (27 October 2000). Quantitative Analysis of N-Acetylcysteine and Its Pharmacopeial Impurities in a Pharmaceutical Formulation by Liquid Chromatography-Uv Detection-Mass Spectrometry. Journal of Chromatography. A, 896 (1-2), 191-9. doi:10.1016/S0021-9673(00)00741-X

Toussaint, B., Streel, B., Ceccato, A., Hubert, P., & Crommen, J. (27 October 2000). Determination of the Enantiomers of 3-Tert.-Butylamino-1,2-Propanediol by High-Performance Liquid Chromatography Using Mass Spectrometric Detection. Journal of Chromatography. A, 896 (1-2), 201-7. doi:10.1016/S0021-9673(00)00558-6

Toussaint, B., Duchateau, A. L., van der Wal, S., Albert, A., Hubert, P., & Crommen, J. (October 2000). Comparative Evaluation of Four Detectors in the High-Performance Liquid Chromatographic Analysis of Chiral Nonaromatic Alcohols. Journal of Chromatographic Science, 38 (10), 450-7. doi:10.1093/chromsci/38.10.450

Toussaint, B., Duchateau, A. L., van der Wal, S., Albert, A., Hubert, P., & Crommen, J. (25 August 2000). Determination of the Enantiomers of 3-Tert.-Butylamino-1,2-Propanediol by High-Performance Liquid Chromatography Coupled to Evaporative Light Scattering Detection. Journal of Chromatography. A, 890 (2), 239-49. doi:10.1016/S0021-9673(00)00609-9

Fillet, M., Hubert, P., & Crommen, J. (14 April 2000). Enantiomeric Separations of Drugs Using Mixtures of Charged and Neutral Cyclodextrins. Journal of Chromatography. A, 875 (1-2), 123-34. doi:10.1016/S0021-9673(00)00084-4

Marini Djang'Eing'A, R., Pantella, A., Chiap, P., Bimazubute, M. A., Hubert, P., & Crommen, J. (April 2000). Development and validation of an LC method for the determination of six corticosteroids, salicylic acid and parabens in different pharmaceutical formulations [Paper presentation]. IXth Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

Chiap, P., Buraglia, B. M., Ceccato, A., Hubert, P., & Crommen, J. (10 February 2000). Automated Liquid Chromatographic Determination of Atenolol in Plasma Using Dialysis and Trace Enrichment on a Cation-Exchange Precolumn for Sample Handling. Journal of Chromatography. B, Biomedical Sciences and Applications, 739 (1), 205-17. doi:10.1016/S0378-4347(99)00518-6

Chiap, P., Evrard, B., Bimazubute, M. A., De Tullio, P., Hubert, P., Delattre, L., & Crommen, J. (10 February 2000). Determination of Albendazole and Its Main Metabolites in Ovine Plasma by Liquid Chromatography with Dialysis as an Integrated Sample Preparation Technique. Journal of Chromatography. A, 870 (1-2), 121-34. doi:10.1016/S0021-9673(99)00938-3

Toussaint, B., Hubert, P., Tjaden, U. R., van der Greef, J., & Crommen, J. (10 February 2000). Enantiomeric Separation of Clenbuterol by Transient Isotachophoresis-Capillary Zone Electrophoresis-Uv Detection New Optimization Technique for Transient Isotachophoresis. Journal of Chromatography. A, 871 (1-2), 173-80. doi:10.1016/S0021-9673(99)00983-8

Toussaint, B., Gysler, J., Hubert, P., Tjaden, U. R., van der Greef, J., & Crommen, J. (February 2000). In-Line Concentration and Enantioseparation of Clenbuterol by Transient Isotachophoresis-Capillary Zone Electrophoresis-Uv Detection. Biomedical Chromatography: BMC, 14 (1), 32-3. doi:10.1002/(SICI)1099-0801(200002)14:1<32::AID-BMC960>3.0.CO;2-J

Abushoffa, A., Fillet, M., Hubert, P., & Crommen, J. (2000). Separation of aminoglutethimide enantiomers using single and dual cyclodextrin systems in capillary electrophoresis [Paper presentation]. 9e Forum des Sciences Pharmaceutiques, Blankenberge, Belgium.

Chankvetadze, B., Fillet, M., Burjanadze, N., Bergenthal, D., Bergander, C., Luftmann, H., Crommen, J., & Blaschke, G. (2000). Enantioseparation of aminoglutethimide with cyclodextrins in capillary electrophoresis and studies of selector-selectand interactions using NMR spectroscopy and electrospray ionization mass spectrometry. Enantiomer, 5 (3-4), 313-22.

Chiap, P., Hubert, P., Boulanger, B., & Crommen, J. (2000). Plans d’expérience en biolanalyse : optimisation d’une méthode de dialyse pour le traitement d’échantillons plasmatiques préalable à leur analyse chromatographique [Paper presentation]. Journées du GMP, Bordeaux, France.

Chiap, P., Hubert, P., & Crommen, J. (2000). Techniques de préparation basées sur l'utilisation de membranes pour le traitement des échantillons biologiques préalable à leur analyse chromatographique. STP Pharma Pratiques, 10 (6), 361-374.

Crommen, J., Abushoffa, A., Fillet, M., & Hubert, P. (2000). Enantiomeric separation of drugs by capillary electrophoresis using dual cyclodextrin systems [Paper presentation]. EUFEPS 2000, Budapest, Hungary.

Crommen, J., Chiap, P., Fleischer, C. T., Boos, K. S., & Hubert, P. (2000). New trends in automated sample preparation coupled to LC for the determination of drugs in biological fluids [Paper presentation]. IXth International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2000), Basel, Switzerland.

Crommen, J., Chiap, P., & Hubert, P. (2000). Recent developments in automted sample preparation coupled to liquid chromatography for bioanalytical applications [Paper presentation]. Vth International Lichrospher ADS User Meeting, Munich, Germany.

Crommen, J., Fillet, M., Abushoffa, A., & Hubert, P. (2000). The use of dual cyclodextrin systems for enantiomeric separations in capillary electrophoresis : is it the panacea ? [Paper presentation]. XXIIIrd International Symposium on Capillary Chromatography, Riva del garda, Italy.

Fillet, M., Abushoffa, A., Hubert, P., & Crommen, J. (2000). Model for selectivity optimizations by capillary electrophoresis using dual cyclodextrin systems [Paper presentation]. XIIIth International Symposium on High Performance Capillary Electrophoresis, Saarbrucken, Germany.

Fillet, M., Bechet, I., Fotsing, L., Piette, V., & Crommen, J. (2000). Separation of non-steroidal anti-inflammatory drugs by capillary electrophoresis using non-aqueous electrolyte. Biomedical Chromatography: BMC, 14 (1), 12-3. doi:10.1002/(sici)1099-0801(200002)14:1<12::aid-bmc948>3.0.co;2-%23

Fotsing, L., Boulanger, B., Chiap, P., Fillet, M., Hubert, P., & Crommen, J. (2000). Multivariate optimization approach for the separation of water-soluble vitamins and related compounds by capillary electrophoresis. Biomedical Chromatography: BMC, 14 (1), 10-1. doi:10.1002/(SICI)1099-0801(200002)14:1<10::AID-BMC947>3.0.CO;2-8

Fotsing, L., Fillet, M., Boulanger, B., Chiap, P., Hubert, P., & Crommen, J. (2000). Determination of water-soluble vitamins and related compounds by capillary electrophoresis using a multivariate approach for method development [Poster presentation]. XIIIth International Symposium on High Performance Capillary Electrophoresis, Saarbrucken, Germany.

Hubert, P., Boulanger, B., Chiap, P., Dewé, W., & Crommen, J. (2000). Analyse statistique des résultats de validation de méthodes d’analyse chromatographiques [Paper presentation]. Les Journées du GMP, Bordeaux, France.

Piette, V., Fillet, M., Lindner, W., & Crommen, J. (2000). Non-aqueous capillary electrophoretic enantioseparation of N-derivatized amino acids using cinchona alkaloids and derivatives as chiral counter-ions. Journal of Chromatography. A, 875 (1-2), 353-60. doi:10.1016/S0021-9673(00)00083-2

Piette, V., Fillet, M., Lindner, W., & Crommen, J. (2000). Enantiomeric separation of amino acid derivatives by non-aqueous capillary electrophoresis using quinine and related compounds as chiral additives. Biomedical Chromatography: BMC, 14 (1), 19-21. doi:10.1002/(SICI)1099-0801(200002)14:1<19::AID-BMC951>3.0.CO;2-Z

Toussaint, B., Duchateau, A. L. L., Van der Wal, S., Hubert, P., & Crommen, J. (2000). Comparative evaluation of four detectors in the HPLC analysis of chiral non-aromatic alcohols [Paper presentation]. 9e Forum des Sciences Pharmaceutiques, Blankenberge, Belgium.

Toussaint, B., Pitti, C., Streel, B., Ceccato, A., Hubert, P., & Crommen, J. (2000). Quantitative analysis of N-acetylcysteine and its pharmacopeial impurities in a pharmaceutical formulation by LC-UV-MS [Poster presentation]. 6th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers (HTC-6), Brugge, Belgium.

Toussaint, B., Streel, B., Ceccato, A., Hubert, P., & Crommen, J. (2000). Determination of N-acetylcysteine and its metabolites in plasma by LC-MS-MS [Poster presentation]. 6th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers (HTC-6), Brugge, Belgium.

Toussaint, B., Streel, B., Ceccato, A., Hubert, P., & Crommen, J. (2000). Determination of 3-tert.butylamino-1,2-propanediol enantiomers by LC-MS-MS [Poster presentation]. 6th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers (HTC-6), Brugge, Belgium.

De Tullio, P., Felekidis, A., Liégeois, J.-F., Pirotte, B., Stachow, M., Kempen, I., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (26 November 1999). Enantiomeric resolution of pirlindole at the preparative scale: derivatization and chromatographic methods [Poster presentation]. Chirality: Impact in Drug Design and Development, Braine l'Alleud, Belgium.

De Tullio, P., Felekidis, A., Liégeois, J.-F., Pirotte, B., Stachow, M. H., Kempen, I., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (26 November 1999). Enantiomeric resolution of pirlindole at the preparative scale: derivatization and chromatographic methods [Poster presentation]. Chirality: Impact in Drug Design and Development, Braine l’Alleud, Belgium.

Bimazubute, M., Chiap, P., Fotsing, L., Hubert, P., & Crommen, J. (1999). Method development and validation for the LC quantitative analysis of bacitracin in a pharmaceutical formulation [Poster presentation]. XXIIIrd International Symposium on High Performance Liquid Phase Separations and Related Techniques, Grenade, Spain.

Ceccato, A., Toussaint, B., Chiap, P., Hubert, P., & Crommen, J. (1999). Automated Sample Preparation Techniques for the Determination of Drug Enantiomers in Biological Fluids Using Liquid Chromatography with Chiral Stationary Phases. Enantiomer, 4 (3-4), 305-15.

Chiap, P., Evrard, B., Bimazubute, M., De Tullio, P., Hubert, P., Delattre, L., & Crommen, J. (1999). On-line combinaison of dialysis with liquid chromatography for the automated determination of albendazole and its main metabolites in ovine plasma [Paper presentation]. VIIIème Forum des Sciences Pharmaceutiques, Spa, Belgium.

Chiap, P., Hubert, P., Bimazubute, M., Evrard, B., Delattre, L., & Crommen, J. (1999). LC determination of albendazole and its main metabolites in ovine plasma using dialysis as integrated sample preparation technique [Poster presentation]. XXIIIrd International Symposium on High Performance Liquid Phase Separations and Related Techniques, Grenade, Spain.

Chiap, P., Hubert, P., Boulanger, B., & Crommen, J. (1999). Validation of an automated method for the liquid chromatographic determination of atenolol in plasma: application of a new validation protocol. Analytica Chimica Acta, 391 (2), 227-238. doi:10.1016/S0003-2670(99)00117-8

Chiap, P., Toussaint, B., Hubert, P., & Crommen, J. (1999). Automated LC determination of drugs and metabolites in plasma using dialysis and trace enrichment as on-line sample preparation techniques [Paper presentation]. 1st International Symposium on SBS, Separation in the Biosciences, Amsterdam, Netherlands.

Crommen, J., Chiap, P., Ceccato, A., & Hubert, P. (1999). Fully automated methods for the LC determination of drug enantiomers in plasma using precolumns with Restricted Access Material (RAM) for sample pretreatement [Paper presentation]. Internationales LiChrospher ADS Anwender Treffen, Munich, Germany.

Crommen, J., Chiap, P., Toussaint, B., Ceccato, A., & Hubert, P. (1999). Développement et validation de méthodes entièrement automatisées pour le dosage de médicaments et de leurs métabolites dans les fluides biologiques [Paper presentation]. SEP’99 Techniques séparatives et couplages, Lyon, France.

Crommen, J., Fillet, M., Abushoffa, A., Fotsing, L., & Hubert, P. (1999). Design of dual cyclodextrin systems in capillary electrophoresis for selectivity optimisation in enantiomeric separations [Paper presentation]. Balaton Symposium’99, Siofok, Hungary.

Crommen, J., Fillet, M., Abushoffa, A., Fotsing, L., & Hubert, P. (1999). Design of dual cyclodextrin systems in capillary electrophoresis for selectivity optimisation in chiral analysis [Paper presentation]. 8th International Meeting on Recent Development in Pharmaceutical Analysis (RDPA’99), Rome, Italy.

Crommen, J., Fillet, M., Fotsing, L., & Hubert, P. (1999). Method development strategies for enantiomeric separations by capillary electrophoresis using charged and neutral cyclodextrin derivatives as chiral selectors [Paper presentation]. IIIrd Miniaturisation in Liquid Chromatography versus Capillary Electrophoresis Conference, Gent, Belgium.

Crommen, J., Fotsing, L., Fillet, M., Chiap, P., & Hubert, P. (1999). Method development and validation for the CE analysis of multi-vitamin formulations [Paper presentation]. Xth International Symposium on Pharmaceutical and Biomedical Analysis, Washington, United States.

De Tullio, P., Ceccato, A., Liégeois, J.-F., Pirotte, B., Felekidis, A., Stachow, M., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (1999). Effective resolution of racemic pirlindole at the preparative scale. Chirality, 11, 261-266. doi:10.1002/(SICI)1520-636X(1999)11:4<261::AID-CHIR1>3.0.CO;2-S

Evrard, B., De Tullio, P., Chiap, P., Van Hees, T., Piel, G., Crommen, J., Losson, B., & Delattre, L. (1999). The effect of hydroxypropyl-b-cyclodextrins on the pharamacokinetics of albendazole in sheep. In Proceedings of 26th International Symposium on Controlled Release of Bioactive Materials.

Fillet, M., Bechet, I., Piette, V., & Crommen, J. (1999). Separation of nonsteroidal anti-inflammatory drugs by capillary electrophoresis using nonaqueous electrolytes. Electrophoresis, 20 (9), 1907-15. doi:10.1002/(SICI)1522-2683(19990701)20:9<1907::AID-ELPS1907>3.0.CO;2-L

Fillet, M., Chankvetadze, B., Crommen, J., & Blaschke, G. (1999). Designed combination of chiral selectors for adjustment of enantioseparation selectivity in capillary electrophoresis. Electrophoresis, 20 (13), 2691-7. doi:10.1002/(SICI)1522-2683(19990901)20:13<2691::AID-ELPS2691>3.0.CO;2-S

Fillet, M., Chankvetadze, B., Hubert, P., & Crommen, J. (1999). Selectivity enhancement for enantiomeric separations in capillary electrophoresis using dual cyclodextrin systems [Paper presentation]. 23rd International Symposium on high performance liquid phase separations and related techniques, Grenade, Spain.

Fotsing, L., Boulanger, B., Chiap, P., Fillet, M., Hubert, P., & Crommen, J. (1999). Multivariate optimisation approach for the separation of water-soluble vitamins and related compounds by capillary electrophoresis [Poster presentation]. IIIrd Miniaturisation in Liquid Chromatography versus Capillary Electrophoresis Conference, Gand, Belgium.

Fotsing, L., Boulanger, B., Chiap, P., Fillet, M., Hubert, P., & Crommen, J. (1999). Determination of copper, iron and zinc in pharmaceutical formulations by capillary electrophoresis [Poster presentation]. 23rd International Symposium on high performance liquid phase separations and related techniques, Grenade, Spain.

Fotsing, L., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (1999). Study of adsorption effects in the analysis of pharmaceutical formulations by CE. Journal de Pharmacie de Belgique, 54.

Fotsing, L., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (1999). Studies on the variability of migration times observed in the analysis of pharmaceutical formulations by capillary electrophoresis [Paper presentation]. 8e Forum des Sciences Pharmaceutiques, Spa, Belgium.

Fotsing, L., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (1999). Elimination of adsorption effects in the analysis of water-soluble vitamins in pharmaceutical formulations by capillary electrophoresis. Journal of Chromatography. A, 853 (1-2), 391-401. doi:10.1016/S0021-9673(99)00524-5

Fotsing, L., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (1999). Elimination of adsorption effects in the analysis of pharmaceutical formulations by capillary electrophoresis [Poster presentation]. XIIth International Symposium on High Performance Capillary Electrophoresis, Palm Springs, United States.

Hubert, P., Ceccato, A., Chiap, P., Toussaint, B., & Crommen, J. (1999). Préparation des échantillons d'origine biologique préalable à leur analyse chromatographique. STP Pharma Pratiques, 9 (2), 160-180.

Hubert, P., Chiap, P., Crommen, J., Boulanger, B., Chapuzet, E., Mercier, N., Bervoas-Martin, S., Chevalier, P., Grandjean, D., Lagorce, P., Lallier, M., Laparra, M. C., Laurentie, M., & Nivet, J. C. (1999). The SFSTP guide on the validation of chromatographic methods for drug bioanalysis: from the Washington Conference to the laboratory. Analytica Chimica Acta, 391 (2), 135-148. doi:10.1016/S0003-2670(99)00106-3

Piette, V., Fillet, M., Hubert, P., & Crommen, J. (1999). Enantiomeric separation of N-derivatised amino acids by non-aqueous capillary electrophoresis using cinchona alkaloids and derivatives as chiral selectors [Poster presentation]. 23rd International Symposium on high performance liquid phase separations and related techniques, Grenade, Spain.

Piette, V., Fillet, M., Hubert, P., & Crommen, J. (1999). Enantiomeric separation of amino acid derivatives by non-aqueous capillary electrophoresis using quinine and related compounds as chiral additives [Poster presentation]. IIIrd Miniaturisation in Liquid Chromatography versus Capillary Electrophoresis Conference, Gent, Belgium.

Toussaint, B., Bergmann, J., Hubert, P., Tjaden, U. R., Van der Greef, J., & Crommen, J. (1999). MS compatible method for the preconcentration of clenbuterol enantiomers prior to enantiomeric separation using transient ITP-CZE-UV [Paper presentation]. 8e Forum des Sciences Pharmaceutiques, Spa, Belgium.

Toussaint, B., Bergmann, J., Hubert, P., Tjaden, U. R., Van der Greef, J., & Crommen, J. (1999). In-line concentration and enantioseparation of clenbuterol by transient ITP-CE-UV [Poster presentation]. IIIrd Miniaturisation in Liquid Chromatography versus Capillary Electrophoresis Conference, Gand, Belgium.

Toussaint, B., Bergmann, J., Hubert, P., Tjaden, U. R., Van der Greef, J., & Crommen, J. (1999). Enantiomeric separation of clenbuterol by transient ITP-CE-MS [Poster presentation]. HPLC’99, 23rd International Symposium on high performance liquid phase sepa-rations and related techniques, Grenade, Spain.

Vander Heyden, Y., Saevels, J., Roets, E., Hoogmartens, J., Decolin, D., Quaglia, M. G., Van den Bossche, W., Leemans, R., Smeets, O., Van de Vaart, F., Mason, B., Taylor, G. C., Underberg, W., Bult, A., Chiap, P., Crommen, J., De Beer, J., Hansen, S. H., & Massart, D. L. (1999). Interlaboratory studies on two high-performance liquid chromatographic assays for tylosin (tartrate). Journal of Chromatography. A, 830 (1), 3-28. doi:10.1016/S0021-9673(98)00840-1

Ceccato, A., Hubert, P., De Tullio, P., Liégeois, J.-F., Felikidis, A., Geczy, J., & Crommen, J. (December 1998). Enantiomeric Separation of Pirlindole by Liquid Chromatography Using Different Types of Chiral Stationary Phases. Journal of Pharmaceutical and Biomedical Analysis, 18 (4-5), 605-14. doi:10.1016/S0731-7085(98)00213-1

Fillet, M., Hubert, P., & Crommen, J. (November 1998). Method Development Strategies for the Enantioseparation of Drugs by Capillary Electrophoresis Using Cyclodextrins as Chiral Additives. Electrophoresis, 19 (16-17), 2834-40. doi:10.1002/elps.1150191608

Ceccato, A., Boulanger, B., Chiap, P., Hubert, P., & Crommen, J. (11 September 1998). Simultaneous Determination of Methylphenobarbital Enantiomers and Phenobarbital in Human Plasma by on-Line Coupling of an Achiral Precolumn to a Chiral Liquid Chromatographic Column. Journal of Chromatography. A, 819 (1-2), 143-53. doi:10.1016/S0021-9673(98)00547-0

Ceccato, A., Hubert, P., De Tullio, P., Liégeois, J.-F., Stachow, M., Geczy, J., & Crommen, J. (01 September 1998). Simultaneous Determination of Pirlindole Enantiomers and Dehydropirlindole by Chiral Liquid Chromatography. Journal of Pharmaceutical and Biomedical Analysis, 17 (6-7), 1071-9. doi:10.1016/S0731-7085(98)00073-9

De Tullio, P., Ceccato, A., Liégeois, J.-F., Pirotte, B., Felekidis, A., Stachow, M., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (September 1998). Preparative resolution of racemic pirlindole: chromatographic methods and determination of the absolute configuration [Poster presentation]. Fourth European Congress of Pharmaceutical Sciences, Milan, Italy.

De Tullio, P., Ceccato, A., Liégeois, J.-F., Pirotte, B., Felekidis, A., Stachow, M., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (September 1998). Effective resolution of racemic pirlindole at the preparative scale: derivatization method and absolute configuration [Poster presentation]. XVth EFMC International Symposium on Medicinal Chemistry.

De Tullio, P., Ceccato, A., Felekidis, A., Liégeois, J.-F., Pirotte, B., Stachow, M., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (16 January 1998). Séparation énantiomérique du pirlindole à l’échelle préparative [Poster presentation]. Journées Jeunes Chercheurs, Paris, France.

Ceccato, A., Hubert, P., De Tullio, P., Liégeois, J.-F., Felikidis, A., Geczy, J., & Crommen, J. (1998). Liquid chromatographic separation of pirlindole enantiomers using different types of chiral stationary phases. Journal de Pharmacie de Belgique, 53, 168.

Ceccato, A., Hubert, P., De Tullio, P., Liégeois, J.-F., Stachow, M., Geczy, J., & Crommen, J. (1998). Determination of the enantiomeric purity of pirlindole by liquid chromatography using a cellulose based chiral stationary phase. Journal de Pharmacie de Belgique, 53, 169.

Chiap, P., Boulanger, B., Bimazubute, M., Hubert, P., & Crommen, J. (1998). Validation of an automated method for the LC determination of atenolol in plasma : application of a new validation strategy. Journal de Pharmacie de Belgique, 53, 171.

Chiap, P., Boulanger, B., Ceccato, A., Hubert, P., & Crommen, J. (1998). On-line coupling of dialysis to liquid chromatography for the automated determination of some local anaesthetics in human plasma. Journal de Pharmacie de Belgique, 53, 172.

Chiap, P., Planck, I., Evrard, B., Hubert, P., Delattre, L., & Crommen, J. (1998). Automated determination of acyclovir in human plasma using solid phase extraction and liquid chromatography. Journal de Pharmacie de Belgique, 53, 172.

Crommen, J., Ceccato, A., Fillet, M., Chiap, P., Toussaint, B., & Hubert, P. (1998). Method development and validation for the individual quantitation of drug en-antiomers using liquid chromatography or capillary electrophoresis [Paper presentation]. 3rd course on chiral chemistry, Project Tempus S-JEP-09101-95 « New Curriculum in Chiral Chemistry ».

Crommen, J., Chiap, P., Toussaint, B., Ceccato, A., & Hubert, P. (1998). Sample preparation strategies for the fully automated determination of drugs and metabolites in biologicals fluids [Paper presentation]. XIV Convegno nazionale, divisione di chimica farmaceutica, Società Chimica Italiana, Salsomaggiore Terme -–Parma, Italy.

De Tullio, P., Ceccato, A., Liégeois, J.-F., Pirotte, B., Felekidis, A., Stachow, M., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (1998). Preparative resolution of racemic pirlindole: chromatographic methods and determination of the absolute configuration. European Journal of Pharmaceutical Sciences, suppl.1, 37.

De Tullio, P., Felekidis, A., Liégeois, J.-F., Pirotte, B., Stachow, M., Ceccato, A., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (1998). Résolution préparative du pirlindole. Journal de Pharmacie de Belgique, 53, 55.

De Tullio, P., Felekidis, A., Pirotte, B., Liégeois, J.-F., Stachow, M., Delarge, J., Ceccato, A., Hubert, P., Crommen, J., & Geczy, J. (1998). First preparative enantiomer resolution of pirlindole, a potent antidepressant drug. Helvetica Chimica Acta, 81, 539-547. doi:10.1002/hlca.19980810307

De Tullio, P., Felikidis, A., Liégeois, J.-F., Pirotte, B., Stachow, M., Ceccato, A., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (1998). Résolution préparative du pirlindol, journées franco-belges de pharmacochimie. Journal de Pharmacie de Belgique, 53, 55.

Fillet, M., Fotsing, L., Bonnard, J., & Crommen, J. (1998). Stereoselective determination of S-naproxen in tablets by capillary electrophoresis. Journal of Pharmaceutical and Biomedical Analysis, 18 (4-5), 799-805. doi:10.1016/S0731-7085(98)00218-0

Fillet, M., Fotsing, L., Hubert, P., & Crommen, J. (1998). Stereoselective determination of s-naproxen in tablets by capillary electrophoresis. Journal de Pharmacie de Belgique, 53, 185.

Fillet, M., Fotsing, L., Hubert, P., & Crommen, J. (1998). Selectivity improvement in the capillary electrophoretic enantioseparation of uncharged compounds by use of mixtures of charged and neutral cyclodextrins [Poster presentation]. 10th International Symposium on Chiral Discrimination, Vienne, Austria.

Fillet, M., Fotsing, L., Hubert, P., & Crommen, J. (1998). Enantioseparation of uncharged compounds by capillary electrophoresis using mixtures of anionic and neutral -cyclodextrin derivatives [Poster presentation]. XIth International Symposium on High Performance Capillary Electrophoresis, Orlando, United States.

Fillet, M., Fotsing, L., Piette, V., Hubert, P., & Crommen, J. (1998). Method development strategies for the rapid enantioseparation of drugs by capillary electrophoresis using cyclodextrins as chiral additives. Journal de Pharmacie de Belgique, 53, 184.

Fillet, M., Fotsing, L., Schomburg, G., Hubert, P., & Crommen, J. (1998). Enantioseparation of Acidic Drugs by Capillary Electrophoresis Using Dual Systems with Mixtures of Charged and Neutral Cyclodextrins. Biomedical Chromatography: BMC, 12 (3, May-Jun), 131-2. doi:10.1002/(SICI)1099-0801(199805/06)12:3<131::AID-BMC779>3.0.CO;2-P

Fotsing, L., Fillet, M., Hubert, P., & Crommen, J. (1998). Quantitative analysis of folic acid in a pharmaceutical formulation by capillary electrophoresis. Journal de Pharmacie de Belgique, 53, 185.

Gora, R., Ceccato, A., Toussaint, B., Hubert, P., & Crommen, J. (1998). Automated liquid chromatographic analysis of pirlindole enantiomers in plasma using a precolumn with restricted access material in a column switching system [Paper presentation]. 3rd course on chiral chemistry, Project Tempus S-JEP-09101-95 « New Curriculum in Chiral Chemistry », Bratislava, Slovakia.

Pirotte, B., De Tullio, P., Stachow, M., Felekidis, A., Liégeois, J.-F., Ceccato, A., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (1998). Tentatives de synthèse énantiosélective des isomères R et S du pirlindole. Journal de Pharmacie de Belgique, 53, 60.

Pirotte, B., De Tullio, P., Stachow, M., Felikidis, A., Liégeois, J.-F., Ceccato, A., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (1998). Tentatives de synthèse énantiosélective des isomères R et S du pirlindol. Journal de Pharmacie de Belgique, 53, 60.

Toussaint, B., Ceccato, A., Hubert, P., & Crommen, J. (1998). Quantitative analysis of l-lysine n-acetylcysteinate and related compounds by LC-MS. Journal de Pharmacie de Belgique, 53, 260.

Toussaint, B., Ceccato, A., Hubert, P., & Crommen, J. (1998). Determination of l-lysine N-acetylcysteinate, its mono- and dimeric related compounds by LC-MS-MS [Poster presentation]. 5th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers, Brugge, Belgium.

Toussaint, B., Hubert, P., Ceccato, A., Hurlet, V., Rigo, J. M., COUCKE, P., Moonen, G., & Crommen, J. (1998). Vizualization and structural analysis of a neurotoxic astroglia-released factor by liquid chromatography using fluorescence and mass spectrometric detection [Poster presentation]. Bioforum, Liège, Belgium.

Toussaint, B., Hubert, P., Hofte, B., Moonen, G., Tjaden, U. R., Van der Greef, J., & Crommen, J. (1998). Struture elucidation of a neurotoxic astroglia-released factor by liquid chromatography and mass spectrometric detection [Poster presentation]. 15th Symposium on liquid chromatography / Mass spectrometry, Montreux, Switzerland.

Ceccato, A., Chiap, P., Hubert, P., & Crommen, J. (26 September 1997). Automated Determination of Tramadol Enantiomers in Human Plasma Using Solid-Phase Extraction in Combination with Chiral Liquid Chromatography. Journal of Chromatography. B, Biomedical Sciences and Applications, 698 (1-2), 161-70. doi:10.1016/S0378-4347(97)00267-3

Ceccato, A., Hubert, P., De Tullio, P., Liégeois, J.-F., Pirotte, B., Stachow, M., Delarge, J., Geczy, J., & Crommen, J. (September 1997). Simultaneous determination of pirlindole enantiomers and dehydropirlindole by liquid chromatography using a cellulose based chiral stationary phase [Poster presentation]. 7th Meeting on Recent Developments in Pharmaceutical Analysis, Ile d'Elbe, Italy.

Piel, G., Fillet, M., Evrard, B., Crommen, J., & Delattre, L. (July 1997). Comparison of the binding constant values of complexes of different antimycotic imidazole derivatives with cyclodextrin obtained by capillary electrophoresis and phase solubility diagram [Poster presentation]. Pharmaceutical applications of cyclodextrins conference, Lawrence, Kansas, United States.

Ceccato, A., Toussaint, B., Chiap, P., Hubert, P., & Crommen, J. (June 1997). Enantioselective Determination of Oxprenolol in Human Plasma Using Dialysis Coupled on-Line to Reversed-Phase Chiral Liquid Chromatography. Journal of Pharmaceutical and Biomedical Analysis, 15 (9-10), 1365-74. doi:10.1016/S0731-7085(96)01965-6

De Tullio, P., Felekidis, A., Liégeois, J.-F., Pirotte, B., Stachow, M., Ceccato, A., Hubert, P., Crommen, J., Cegzy, J., & Delarge, J. (May 1997). Résolution préparative du pirlindole [Poster presentation]. Onzièmes Journées Franco-Belges de Pharmacochimie, Bruxelles, Belgium.

Fotsing, L., Fillet, M., Bechet, I., Hubert, P., & Crommen, J. (May 1997). Determination of Six Water-Soluble Vitamins in a Pharmaceutical Formulation by Capillary Electrophoresis. Journal of Pharmaceutical and Biomedical Analysis, 15 (8), 1113-23. doi:10.1016/S0731-7085(96)02010-9

Pirotte, B., De Tullio, P., Stachow, M., Felekidis, A., Liégeois, J.-F., Ceccato, A., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (May 1997). Tentatives de synthèse énantiosélective des isomères R et S du pirlindole [Poster presentation]. Onzièmes Journées Franco-Belges de Pharmacochimie, Bruxelles, Belgium.

Ceccato, A., Boulanger, B., Chiap, P., Hubert, P., & Crommen, J. (1997). LC determination of mephobarbital enantiomers and phenobarbital in plasma using a precolumn with restricted access sorbent for sample clean-up [Poster presentation]. HPLC’ 97, Birmingham, United Kingdom.

Ceccato, A., Chiap, P., Hubert, P., & Crommen, J. (1997). Coupled-column LC analysis of mephobarbital enantiomers in plasma using restricted access packing material in the precolumn [Paper presentation]. VIth Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

Ceccato, A., Chiap, P., Hubert, P., & Crommen, J. (1997). Automated determination of tramadol enantiomers in plasma using solid-phase extraction and chiral liquid chromatography [Poster presentation]. VIIIth International Symposium on Pharmaceutical and Biomedical Analysis, Orlando, United States.

Ceccato, A., Hubert, P., De Tullio, P., Liégeois, J.-F., Pirotte, B., Stachow, M., Delarge, J., Geczy, J., & Crommen, J. (1997). Enantiomeric separation of pirlindole enantiomers and dehydroprilindole by chrial liquid chromatography [Poster presentation]. VIIth meeting on recent developments in pharmaceutical analysis.

Chiap, P., Ceccato, A., Miralles, B., Boulanger, B., Hubert, P., & Crommen, J. (1997). On-line combination of dialysis with trace enrichment on a cation-exchange precolumn for the automated LC determination of sotalol in plasma [Poster presentation]. HPLC 97, Birmingham, United Kingdom.

Chiap, P., Hubert, P., Ceccato, A., & Crommen, J. (1997). Automated LC determination of molsidomine and two of its metabolites in plasma using solid phase extraction as sample pretreatment [Poster presentation]. HPLC’ 97, Birmingham, United Kingdom.

Chiap, P., Miralles, B., Ceccato, A., Hubert, P., & Crommen, J. (1997). Automated liquid chromatographic determination of atenolol in plasma using dialysis and trace enrichment on a cation exchange precolumn for sample pre-treatement [Poster presentation]. VIIth meeting on recent developments in pharmaceutical analysis.

Crommen, J., Ceccato, A., Toussaint, B., Chiap, P., & Hubert, P. (1997). Fully automated systems for the liquid chromatographic determination of drug enantiomers in biological fluids [Paper presentation]. VIIth meeting on recent developments in pharmaceutical analysis.

Crommen, J., Fillet, M., Ceccato, A., & Hubert, P. (1997). Enantiomeric resolution of drugs by capillary electrophoresis [Paper presentation]. 57th FIP World Congress 1997, Vancouver, Canada.

Crommen, J., Fillet, M., Gotti, R., Fotsing, L., & Hubert, P. (1997). Resolution enhancement in the CE separation of drug enantiomers by use of mixtures of charged and neutral cyclodextrins [Paper presentation]. VIIIth International Symposium on Pharmaceutical and Biomedical Analysis, Orlando, United States.

Crommen, J., Fillet, M., Gotti, R., & Hubert, P. (1997). Method development strategies for the chiral analysis of drugs by CE using anionic and uncharged cyclodextrin additives [Paper presentation]. HPLC’ 97, Birmingham, United Kingdom.

Crommen, J., Fillet, M., Schomburg, G., Fotsing, L., & Hubert, P. (1997). Influence of dynamic and permanent surface modification on the performance of CE separations of small molécules [Paper presentation]. Symposium on High Performance Capillary Electrophoresis, Kyoto, Japan.

Duvivier, D. H., Chiap, P., Crommen, J., & Lekeux, P. (1997). Evaluation of some parameters influencing the drug delivery from a dry powder inhalation device using an in vitro model of the horse airways. Veterinary Research, 28 (6), 557-564.

Fillet, M., Bechet, I., Ceccato, A., Hubert, P., & Crommen, J. (1997). Enantiomeric separation of basic drugs by CZE using charged and uncharged cyclodextrins as chiral selectors [Poster presentation]. VIIth International Symposium on High Performance Capillary Electrophoresis, Wurzburg, Germany.

Fillet, M., Bechet, I., Schomburg, G., Hubert, P., & Crommen, J. (1997). The use of mixtures of anaionic and uncharged cyclodextrins for the enantiomeric separation of acidic drugs by capillary electrophoresis [Poster presentation]. IXth International Symposium on High Performance Capillary Electrophoresis, Anaheim, United States.

Fillet, M., Fotsing, L., Hubert, P., & Crommen, J. (1997). Chiral separation of acidic drugs by capillary electrophoresis using charged and uncharged cyclodextrins as buffer additives [Paper presentation]. VIth Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

Fillet, M., Hubert, P., & Crommen, J. (1997). Enantioseparation of nonsteroidal anti-inflammatory drugs by capillary electrophoresis using mixtures of anionic and uncharged beta-cyclodextrins as chiral additives. Electrophoresis, 18 (6), 1013-8. doi:10.1002/elps.1150180625

Fillet, M., Schomburg, G., Hubert, P., & Crommen, J. (1997). Enantioseparation of acidic drugs by capillary electrophoresis using dual systems with mixtures of charged and neutral cyclodextrins as chrial selectors.

Fillet, M., Schomburg, G., Hubert, P., De Graeve, J., & Crommen, J. (1997). Dual cyclodextrin systems for the enantioseparation of acidic drugs by capillary zone electrophoresis [Poster presentation]. HPLC 97, Birmingham, United Kingdom.

Fotsing, L., Fillet, M., Hubert, P., & Crommen, J. (1997). Quantitative analysis of six water-soluble vitamins in a pharmaceutical formulation by capillary electrophoresis [Poster presentation]. HPLC 97, Birmingham, United Kingdom.

Hubert, P., Ceccato, A., Hurlet, V., Rigo, J.-M., Coucke, P., Moonen, G., & Crommen, J. (1997). Automated determination of tramadol enantiomers in plasma using solid-phase extraction and chiral liquid chromatography [Poster presentation]. Second meeting of the Belgian Society of Neuroscience, Brussels, Belgium.

Hubert, P., Hurlet, V., Rigo, J.-M., Coucke, P., Moonen, G., & Crommen, J. (1997). Fluorescence Detection of a Neurotoxic Astroglia-Released Factor Using Gradient Liquid Chromatography after Precolumn Derivatization. Biomedical Chromatography: BMC, 11 (2, Mar-Apr), 93-5. doi:10.1002/(SICI)1099-0801(199703)11:2<93::AID-BMC656>3.0.CO;2-J

Toussaint, B., Ceccato, A., Hubert, P., & Crommen, J. (1997). Determination of N-acetylcysteine and its potential degradation products by LC/MS/MS [Poster presentation]. HPLC 97, Birmingham, United Kingdom.

Toussaint, B., Ceccato, A., Maes, P., Hubert, P., & Crommen, J. (1997). Determination of N-acetylcysteine and its potential degradation products by LC/APCI+/MS/MS [Paper presentation]. VIth Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

Ceccato, A., Chiap, P., Hubert, P., Toussaint, B., & Crommen, J. (25 October 1996). Automated Determination of Verapamil and Norverapamil in Human Plasma with on-Line Coupling of Dialysis to High-Performance Liquid Chromatography and Fluorometric Detection. Journal of Chromatography. A, 750 (1-2), 351-60. doi:10.1016/0021-9673(96)00471-2

Fillet, M., Bechet, I., Hubert, P., & Crommen, J. (June 1996). Resolution Improvement by Use of Carboxymethyl-Beta-Cyclodextrin as Chiral Additive for the Enantiomeric Separation of Basic Drugs by Capillary Electrophoresis. Journal of Pharmaceutical and Biomedical Analysis, 14 (8-10), 1107-14. doi:10.1016/S0731-7085(95)01756-9

Bechet, I., Fillet, M., Hubert, P., & Crommen, J. (1996). Influence of organic modifiers and cyclodextrins on the CZE separation of non-steroidal anti-inflammatory drugs [Poster presentation]. VIIIth International Symposium on High Performance Capillary Electrophoresis, Orlando, United States.

Ceccato, A., Hubert, P., Chiap, P., Toussaint, B., & Crommen, J. (1996). On-line dialysis coupled to liquid chromatography for the automated determination of verapamil and its demethylated metabolite in plasma, chapitre "biomedical analysis with hyphenated chromatography". In Hyphenated techniques in chromatography and hyphenated chromatographic analysers. K.V.C.V.

Ceccato, A., Hubert, P., Chiap, P., Toussaint, B., & Crommen, J. (1996). On-line dialysis coupled to liquid chromatography for the automated determination of verapamil and its demethylated metabolite in plasma [Paper presentation]. 4th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyses, Bruges, Belgium.

Ceccato, A., Toussaint, B., Chiap, P., Hubert, P., & Crommen, J. (1996). LC determination of oxprenolol enantiomers in human plasma using dialysis as on-line sample preparation technique. Journal de Pharmacie de Belgique, 51, 106.

Ceccato, A., Toussaint, B., Miralles, B., Chiap, P., Hubert, P., & Crommen, J. (1996). On-line dialysis coupled to liquid chromatography for the automated determination of oxprenolol enantiomers in human plasma [Poster presentation]. VIIth International Symposium on Pharmaceutical and Biomedical Analysis, Osaka, Japan.

Crommen, J., Chiap, P., Ceccato, A., & Hubert, P. (1996). Analytical technologies and tolls for drug purity testing [Paper presentation]. IIIrd EUFEPS Conference, Nuremberg, Germany.

Crommen, J., Fillet, M., Bechet, I., & Hubert, P. (1996). Chiral separations of drugs by capillary electrophoresis using neutral and charged cyclodextrin derivatives [Paper presentation]. VIIth International Symposium on Pharmaceutical and Biomedical Analysis, Osaka, Japan.

Crommen, J., Fillet, M., Bechet, I., Schomburg, G., & Hubert, P. (1996). Applications of cyclodextrin mediated capillary electrophoresis to the chiral analysis of drugs and related compounds [Paper presentation]. 10th International Symposium on Advances and Applications of Chromatography in Industry, Bratislava, Slovakia.

Fillet, M., Bechet, I., Schomburg, G., Hubert, P., & Crommen, J. (1996). Enhanced resolution in the capillary electrophoresis of drug enantiomers by use of charged cyclodextrin derivatives and dynamically or permanently coated capillaries [Paper presentation]. HPLC’ 96, San Francisco, United States.

Fillet, M., Bechet, I., Schomburg, G., Hubert, P., & Crommen, J. (1996). Enantiomeric separation of acidic drugs by capillary electrophoresis using mixtures of anionic and uncharged cyclodextrins as chiral additives [Paper presentation]. Xth International Symposium on Capillary Electrophoresis and Isotachophoresis, Prague, Czechia.

Fillet, M., Bechet, I., Schomburg, G., Hubert, P., & Crommen, J. (1996). Enantiomeric separation of acidic and basic drugs by capillary electrophoresis using neutral and anionic cyclodextrins. Journal de Pharmacie de Belgique, 51, 110.

Fotsing, L., Bechet, I., Fillet, M., Hubert, P., & Crommen, J. (1996). Determination of water-soluble vitamins by capillary zone electrophoresis. Journal de Pharmacie de Belgique, 51, 110.

Hubert, P., Chiap, P., & Crommen, J. (1996). Strategy for bioanalytical method validation : approach of SFSTP commission [Paper presentation]. KVCV Chemometrics Symposium ‘96, Louvain, Belgium.

Hubert, P., Chiap, P., & Crommen, J. (1996). Method validation in a European context, Chromatografische informatie in cyberspace en in andere moderne media [Paper presentation]. KVCV Symposium, Bruxelles, Belgium.

Hubert, P., Hurlet, V., Rigo, J.-M., Coucke, P., Moonen, G., & Crommen, J. (1996). Fluorescence detection of a neurotoxic astroglia-released factor after precol-umn derivatization and gradient liquid chromatography [Poster presentation]. VIIth International symposium on liminescence spectrometry in biomedical analysis, Nice, France.

Bechet, I., Hubert, P., Crommen, J., & Fillet, M. (April 1995). Quantitative Analysis of Non-Steroidal Anti-Inflammatory Drugs by Capillary Zone Electrophoresis. Journal of Pharmaceutical and Biomedical Analysis, 13 (4-5), 497-503. doi:10.1016/0731-7085(95)01339-M

Bechet, I., Fillet, M., Fotsing, L., Hubert, P., & Crommen, J. (1995). Influence of organic modifiers and complexing agents on the separation of non-steroidal anti-inflammatory drugs by capillary zone electrophoresis. Journal de Pharmacie de Belgique, 50, 305.

Bechet, I., Fillet, M., Fotsing, L., Hubert, P., & Crommen, J. (1995). CZE separation of basic and acidic drug by use of cyclodextrin additives [Poster presentation]. VIIth International Symposium on High Performance Capillary Electrophoresis, Wurzburg, Germany.

Bechet, I., Fillet, M., Hubert, P., & Crommen, J. (1995). Improvement of a chiral resolution in capillary zone electrophoresis by use of cyclodextrin additives [Paper presentation]. Symposium «Miniaturisering in vloeistofchromatografie versus capillaire elektroforese», Gand, Belgium.

Ceccato, A., Hubert, P., Streel, B., Bechet, I., & Crommen, J. (1995). Enantiomeric separaiton of sotalol and other B-blockers on a chiral-AGP column using aliphatic carboxylic acids as ionic modifiers. Journal de Pharmacie de Belgique, 50, 319.

Ceccato, A., Hubert, P., Toussaint, B., Chiap, P., & Crommen, J. (1995). Automated determination of verapamil and norverapamil in human plasma by high performance chromatography using dialysis as on-line sample preparation technique [Poster presentation]. XIXth International Symposium on Column Liquid Chromatography and Related Techniques, Innsbruck, Austria.

Chiap, P., Hubert, P., Ceccato, A., Fillet, M., & Crommen, J. (1995). Automated HPLC analysis of molsidomine and two of its metabolites in human plasma using solid phase extraction as sample preparation. Journal de Pharmacie de Belgique, 50, 320.

Chiap, P., Hubert, P., Ceccato, A., Toussaint, B., & Crommen, J. (1995). Comparison of solid-phase extraction and dialysis as on-line sample preparation procedures for the automated HPLC determination of verapamil and norverapamil in human plasma. Journal de Pharmacie de Belgique, 50, 321.

Crommen, J., Fillet, M., Bechet, I., & Hubert, P. (1995). Enantiomeric separations by capillary electrophoresis applications in pharmaceutical, biomedical and environmental analysis, chapitre #L-7. In B. Buszewski, New analytical methods for environmental control and monitoring. Torun, Poland: Pozkal.

Crommen, J., Fillet, M., Bechet, I., & Hubert, P. (1995). Enantiomeric separations by capillary electrophoresis applications in pharmaceutical, biomedical and environmental analysis [Paper presentation]. IInd National Chromatographic Seminar on Modern Analytical Methods in Control and Monitoring of the Environment, Torun, Poland.

Evrard, B., Delahaut, P., Hubert, P., Crommen, J., & Delattre, L. (1995). Biopharmaceutical aspects of the development of a sulfamethazine oral sustained release bolus for lambs. Journal of Controlled Release, 35, 107-115. doi:10.1016/0168-3659(95)00025-4

Evrard, B., Hubert, P., Chiap, P., Crommen, J., & Delattre, L. (1995). A fully automated HPLC method for pharmacokinetic studies on a long-acting sulfamethazine veterinary bolus [Paper presentation]. 5th International Symposium on Drug Analysis, Leuven, Belgium.

Evrard, B., Hubert, P., Chiap, P., Crommen, J., & Delattre, L. (1995). A fully automated HPLC method for pharmacokinetic studies on a long-acting sulfamethazine veterinary bolus. Journal de Pharmacie de Belgique, 50, 328.

Fillet, M., Bechet, I., Ceccato, A., Hubert, P., & Crommen, J. (1995). Enantioseparations of basic compounds by capillary electrophoresis using neutral and anionic cyclodextrins [Poster presentation]. VIth International Symposium on Pharmaceutical and Biomedical Analysis, Saint Louis, United States.

Fillet, M., Bechet, I., Chiap, P., Hubert, P., & Crommen, J. (1995). Enantiomeric purity of propranolol by cyclodextrin modified capillary electrophoresis [Poster presentation]. VIth International Symposium on Chiral Discrimination, Saint Louis, United States.

Fillet, M., Bechet, I., Schomburg, G., Hubert, P., & Crommen, J. (1995). Enantiomeric separations of basic drugs by capillary electrophoresis using derivatized cyclodextrins and dynamically or permanently modified capillaries [Poster presentation]. VIIth International Symposium on Chiral Discrimination, Jerusalem, Israel.

Fillet, M., Schomburg, G., Bechet, I., Hubert, P., & Crommen, J. (1995). Enantiomeric separation of basic drugs by cyclodextrin modified capillary electrophoresis using poly(vinyl alcohol) coated fused silica capillaries. Journal de Pharmacie de Belgique, 50, 331.

Fotsing, L., Fillet, M., Bechet, I., Hubert, P., & Crommen, J. (1995). Comparison of Ce and LC methods for the determination of B vitamins in pharmaceutical dosage forms. Journal de Pharmacie de Belgique, 50, 332.

Hubert, P., Chiap, P., Ceccato, A., Bechet, I., & Crommen, J. (1995). Automated determination of camazepam in human plasma by solid phase extraction coupled to HPLC. Journal de Pharmacie de Belgique, 50, 341.

Hubert, P., Chiap, P., Ceccato, A., & Crommen, J. (1995). Validation of bioanalytical methods. Journal de Pharmacie de Belgique, 50, 290.

Hubert, P., Chiap, P., Ceccato, A., & Crommen, J. (1995). Automated solid-phase extraction coupled to HPLC for the determination of drugs in biological fluids. Pharmacy World and Science, 17, 5.

Hubert, P., Chiap, P., Ceccato, A., Fillet, M., & Crommen, J. (1995). Automated determination of acetylsalicylic, salicylic and salicyluric acids in human plasma using solid-phase extraction and HPLC. Journal de Pharmacie de Belgique, 50, 341.

Hubert, P., Chiap, P., Ceccato, A., Streel, B., & Crommen, J. (1995). Determination of several benzodiazepines in plasma using automated solid-phase extraction coupled to high performance chromatography [Poster presentation]. XIXth International Symposium on Column Liquid Chromatography and Related Techniques, Innsbruck, Austria.

Streel, B., Ceccato, A., Chiap, P., Hubert, P., & Crommen, J. (1995). Injection-generated solvent and pH gradients for sample enrichment on injection of large volumes in microclumn liquid chromatography. Biomedical Chromatography: BMC, 9, 254-256.

Streel, B., Hubert, P., Ceccato, A., Chiap, P., & Crommen, J. (1995). Injection-generated solvent and pH gradients for sample enrichment on injection of large volumes in microcolumn liquid chromatography [Poster presentation]. Symposium «Miniaturisering in vloeistofchromatografie versus capillaire elektroforese», Gand, Belgium.

Streel, B., Hubert, P., Ceccato, A., Chiap, P., & Crommen, J. (1995). Determination of phenothiazines by microcolumn liquid chromatography using injection-generated gradient techniques for sample enrichment. Journal de Pharmacie de Belgique, 50, 398.

Streel, B., Zimmer, C., Sibenaler-Dechamps, R., Hubert, P., & Crommen, J. (1995). HPLC determination of fenofibric acid in human plasma using automated solid phase extraction as sample preparation. Journal de Pharmacie de Belgique, 50, 399.

Toussaint, B., Ceccato, A., Chiap, P., Hubert, P., & Crommen, J. (1995). On-line combination of dialysis and liquid chromatography for the automated determination of oxprenolol in human plasma. Journal de Pharmacie de Belgique, 50, 403.

Bechet, I., Fillet, M., Hubert, P., & Crommen, J. (October 1994). Determination of Benzodiazepines by Micellar Electrokinetic Chromatography. Electrophoresis, 15 (10), 1316-21. doi:10.1002/elps.11501501200

Bechet, I., Paques, P., Fillet, M., Hubert, P., & Crommen, J. (June 1994). Chiral Separation of Basic Drugs by Capillary Zone Electrophoresis with Cyclodextrin Additives. Electrophoresis, 15 (6), 818-23. doi:10.1002/elps.11501501115

Hubert, P., Chiap, P., Moors, M., Bourguignon, B., Massart, D. L., & Crommen, J. (08 April 1994). Knowledge-Based System for the Automated Solid-Phase Extraction of Basic Drugs from Plasma Coupled with Their Liquid Chromatographic Determination. Application to the Biodetermination of Beta-Receptor Blocking Agents. Journal of Chromatography. A, 665 (1), 87-99. doi:10.1016/0021-9673(94)87035-7

Bechet, I., Fillet, M., Hubert, P., & Crommen, J. (1994). Quantitative analysis of B-adrenergic blocking agents by capillary zone electrophoresis. Journal de Pharmacie de Belgique, 49, 60.

Bechet, I., Paques, P., Fillet, M., Hubert, P., & Crommen, J. (1994). Determination of Non-Steroidal Anti-Inflammatory Drugs by Capillary Zone Electrophoresis [Poster presentation]. VIth International Symposium on High Performance Capillary Electrophoresis, San Francisco, United States.

Chiap, P., Hubert, P., & Crommen, J. (1994). HPLC determination of some -adrenergic blocking agents in plasma using automated solid-phase extraction and fluorometric detection [Poster presentation]. VIth International Symposium on Luminescence Spectrometry in Biomedical Analysis, Bruges, Belgium.

Chiap, P., Hubert, P., & Crommen, J. (1994). Development of an automated solid phase extraction method coupled to HPLC for the determination of some benzodiazepines in plasma by use of a knowledge-based system. Journal de Pharmacie de Belgique, 49, 61.

Crommen, J., Bechet, I., Fillet, M., & Hubert, P. (1994). Drug quality control by capillary electrophoresis [Paper presentation]. XIth Slovak Conference on Chromatographic methods and their utilization for human health, Stara Lesna, Slovakia.

Crommen, J., Bechet, I., Fillet, M., & Hubert, P. (1994). Determination of acidic and basic drugs by capillary zone electrophoresis [Paper presentation]. Vth International Symposium on Pharmaceutical and Biomedical Analysis, Stockholm, Sweden.

Crommen, J., Bechet, I., Fillet, M., & Hubert, P. (1994). Chiral and achiral separations of basic drugs in capillary electrophoresis using cyclodextrin additives [Paper presentation]. IXth International Symposium on Capillary Electrophoresis, Budapest, Hungary.

Crommen, J., Fillet, M., Bechet, I., Ceccato, A., & Hubert, P. (1994). Chiral separations of basic drugs in capillary electrophoresis using cyclodextrin derivatives as chiral selectors [Paper presentation]. Vth International Symposium on Chiral Discrimination, Stockholm, Sweden.

Fillet, M., Bechet, I., Chiap, P., Hubert, P., & Crommen, J. (1994). Enantiomeric purity determination of propranolol enantiomers by capillary electrophoresis [Poster presentation]. IXth International Symposium on Capillary Electrophoresis, Budapest, Hungary.

Moors, M., Bourguignon, B., Massart, D. L., Hubert, P., Chiap, P., & Crommen, J. (1994). A knowledge-based system for developping solid-phase extraction methods with the ASPEC system, chapitre #D-3. In E. Reid, H. M. Hill, ... I. D. Wilson, Biofluid and tissue analysis for drugs, including hypolipidaemics. Cambridge, United Kingdom: Royal Society of Chemistry.

Hubert, P., Chiap, P., Evrard, B., Delattre, L., & Crommen, J. (08 December 1993). Fully Automated Determination of Sulfamethazine in Ovine Plasma Using Solid-Phase Extraction on Disposable Cartridges and Liquid Chromatography. Journal of Chromatography. A, 622 (1), 53-60. doi:10.1016/0378-4347(93)80249-4

Bechet, I., Paques, P., Ceccato, A., Hubert, P., & Crommen, J. (1993). Analysis of basic drugs by capillary zone electrophoresis [Poster presentation]. 17th International Symposium on Column Chromatography, Hamburg, Germany.

Bechet, I., Paques, P., Hubert, P., & Crommen, J. (1993). Indirect photometric detection in capillary electrophoresis [Paper presentation]. 9th Danube Symposium on Chromatography, Budapest, Hungary.

Ceccato, A., Hubert, P., Streel, B., Bechet, I., & Crommen, J. (1993). HPLC enantiomeric separation of B-blocking drugs using an alpha 1-acid glycoprotein column. Journal de Pharmacie de Belgique, 48, 113.

Ceccato, A., Hubert, P., Streel, B., Bechet, I., & Crommen, J. (1993). Evaluation of an alpha 1-acid glycoprotein chiral stationary phase for the enantioseparation of -blocking drugs [Poster presentation]. 17th International Symposium on Column Chromatography, Hamburg, Germany.

Crommen, J., Bechet, I., Paques, P., Ceccato, A., & Hubert, P. (1993). Method developement and applications of capillary electrophoresis in drug analysis [Paper presentation]. IVth International Symposium on Pharmaceutical and Biomedical Analysis, Baltimore, United States.

Hubert, P., Chiap, P., Ceccato, A., & Crommen, J. (1993). Fully automated systems for the bioanalysis of drugs and metabolites using solid-phase extraction in combination with liquid chromatography [Paper presentation]. 9th International Symposium on Advances and Applications of Chromatography in Industry, Bratislava, Slovakia.

Hubert, P., Chiap, P., Moors, M., Massart, D. L., & Crommen, J. (1993). Development of a knowledge-based system for the autaomated solid-phase extraction of basic drugs from plasma prior to HPLC determination. Journal de Pharmacie de Belgique, 48, 114.

Hubert, P., Chiap, P., Moors, M., Massart, D. L., & Crommen, J. (1993). A hypermedia knowledge-based system for the automated solid-phase extraction of basic drugs from plasma coupled to their HPLC determination [Paper presentation]. 17th International Symposium on Column Chromatography, Hamburg, Germany.

Massart, D. L., Hubert, P., Chiap, P., Moors, M., Crommen, J., & Bourguignon, B. (1993). Knowledge-based systems for method development in solid-phase extraction [Paper presentation]. 10th International Bioanalytical Forum, Guilford, United Kingdom.

Bechet, I., Ceccato, A., Hubert, P., & Crommen, J. (1992). Separation and quantitative analysis of amino acids by capillary zone electrophoresis with indirect photometric detection. Journal de Pharmacie de Belgique, 47, 181.

Bechet, I., Ceccato, A., Hubert, P., Herné, P., & Crommen, J. (1992). Determination of Meprobamate in Pharmaceutical Dosage Forms Also Containing Carbromal by Liquid Chromatography and Indirect Photometric Detection. Journal of Pharmaceutical and Biomedical Analysis, 10 (10-12, Oct-Dec), 995-9. doi:10.1016/0731-7085(91)80110-U

Bechet, I., Hubert, P., Ceccato, A., & Crommen, J. (1992). Automatic determination of diltiazem and desacetyldiltiazem in human plasma using liquid-solid extraction on disposable cartridges coupled to HPLC [Paper presentation]. Vth Symposium on Handling of Environmental and Biological Samples in Chromatography, Baden-Baden, Germany.

Ceccato, A., Hubert, P., Bechet, I., & Crommen, J. (1992). Optimization of separation and sensitivity in the analysis of amino acids by capillary zone electrophoresis and indirect UV detection [Poster presentation]. XIXth International Symposium on Chromatography, Aix en Provence, France.

Ceccato, A., Hubert, P., Bechet, I., & Crommen, J. (1992). Enantiomeric separation of basic drugs on an ovomucoid column. Journal de Pharmacie de Belgique, 47, 249.

Chiap, P., Hubert, P., Bechet, I., & Crommen, J. (1992). Automated HPLC analysis of diltiazem and desacetyldiltiazem in plasma using disposabele extraction cartridges. Journal de Pharmacie de Belgique, 47, 196.

Hubert, P., Chiap, P., Ceccato, A., Bechet, I., Sibenaler-Dechamps, R., Maes, P., & Crommen, J. (1992). Determination of verapamil and norverapamil in human plasma by liquid chromatography: comparison between a liquid-liquid extraction procedure and an automated liquid-solid extraction method for sample preparation. Journal of Pharmaceutical and Biomedical Analysis, 10 (10-12), 937-42. doi:10.1016/0731-7085(91)80102-F

Hubert, P., Chiap, P., Ceccato, A., & Crommen, J. (1992). HPLC determination of propranolol, verapamil and norverapamil in plasma using automated liquid-solid extraction and fluorometric detection. Journal de Pharmacie de Belgique, 47, 196.

Hubert, P., Chiap, P., Sibenaler-Dechamps, R., Maes, P., & Crommen, J. (1992). Comparison of liquid-liquid extraction and liquid-solid extraction methods for the HPLC determination of verapamil and norverapamil in human plasma. Journal de Pharmacie de Belgique, 47, 259.

Hubert, P., Evrard, B., Delattre, L., & Crommen, J. (1992). Automated determination of sulfadimidine in ovine plasma by solid phase extraction and HPLC. Journal de Pharmacie de Belgique, 47, 197.

Hubert, P., Renson, M., Gerardy-Moies, C., Bechet, I., & Crommen, J. (1992). Comparison between column switching and SPE on disposable cartridges in the automatic determination of indomethacin in plasma by HPLC. Journal de Pharmacie de Belgique, 47, 197.

Maes, P., Sibenaler-Dechamps, R., Zimmer, C., Renson, M., Hubert, P., & Crommen, J. (1992). Comparison of two automated solid-phase extraction methods for the HPLC determination of nifedipine in human plasma with electrochemical detection. Journal de Pharmacie de Belgique, 47, 198.

Bechet, I., Hubert, P., & Crommen, J. (1991). Indirect photometric detection of amino acids in capillary zone electrophoresis. Journal de Pharmacie de Belgique, 46, 143.

Crommen, J., Bechet, I., & Hubert, P. (1991). Indirect detection techniques in liquid chromatography and capillary electrophoresis [Paper presentation]. VIIIth Danube Symposium on Chromatography, Warshaw, Poland.

Hubert, P., Chiap, P., & Crommen, J. (1991). Fully automated analysis of basic drugs in plasma using liquid-solid extraction on individual cartridges and HPLC [Paper presentation]. IIIrd International Symposium on Pharmaceutical and Biomedical Analysis, Boston, United States.

Hubert, P., Chiap, P., & Crommen, J. (1991). Automatic Determination of Diltiazem and Desacetyldiltiazem in Human Plasma Using Liquid-Solid Extraction on Disposable Cartridges Coupled to Hplc--Part II: Optimization of Liquid-Solid Extraction. Journal of Pharmaceutical and Biomedical Analysis, 9 (10-12), 883-887. doi:10.1016/0731-7085(91)80018-5

Hubert, P., Chiap, P., & Crommen, J. (1991). Automatic Determination of Diltiazem and Desacetyldiltiazem in Human Plasma Using Liquid-Solid Extraction on Disposable Cartridges Coupled to Hplc--Part I: Optimization of the Hplc System and Method Validation. Journal of Pharmaceutical and Biomedical Analysis, 9 (10-12), 877-882. doi:10.1016/0731-7085(91)80017-4

Hubert, P., Chiap, P., & Crommen, J. (1991). Automatic determination of diltiazem and desacetyldiltiazem in human plasma using liquid-solid extraction on disposable cartridges coupled to HPLC [Poster presentation]. Vth Symposium on Handling of Environmental and Biological Samples in Chromatography, Baden-Baden, Germany.

Hubert, P., & Crommen, J. (1991). Fully automated determination of verapamil and norverapamil in plasma using liquid-solid extraction and HPLC with fluorescence detection [Poster presentation]. IVth International Symposium on Quantitative Luminescence Spectroscopy in Biomedical Sciences, Gand, Belgium.

Hubert, P., Maes, P., & Crommen, J. (1991). Fully automated analysis of verapamil and norverapamil in plasma by on-line coupling of liquid-solid extraction to HPLC. Journal de Pharmacie de Belgique, 46, 148.

Hubert, P., & Crommen, J. (1990). Optimisation of automated liquid-solid extraction using disposable cartridges in the HPLC analysis of drugs in plasma [Poster presentation]. IInd International Symposium on Pharmaceutical and Biomedical Analysis, York, United Kingdom.

Hubert, P., & Crommen, J. (1990). Fully automated determination of indomethacin in plasma using liquid-solid extraction coupled to HPLC. Journal de Pharmacie de Belgique, 45, 92.

Reginster, J.-Y., Crommen, J., Renson, M., & Franchimont, P. (1990). Percutaneous administration of indomethacin in rheumatoid arthritis, evaluation of two topical preparations. Current Therapeutic Research, 47 (3), 548-553.

Hubert, P., Renson, M., & Crommen, J. (1989). A fully automated HPLC method for the determination of indomethacin in plasma [Poster presentation]. IIIrd International Symposium on Drug Analysis, Antwerp, Belgium.

Hubert, P., Renson, M., & Crommen, J. (1989). A Fully Automated High-Performance Liquid Chromatographic Method for the Determination of Indomethacin in Plasma. Journal of Pharmaceutical and Biomedical Analysis, 7 (12), 1819-27. doi:10.1016/0731-7085(89)80199-2

Bontemps, J., Bettendorff, L., Lombet, J., Grandfils, C., Dandrifosse, G., Schoffeniels, E., Crommen, J., & Nevejans, M. (1984). Poly(styrene-divinylbenzene) as reversed phase adsorbent for the high-performance liquid chromatographic analysis of thiochrome derivatives of thiamine and phosphorylated esters. Journal of Chromatography. A, 295, 486-491. doi:10.1016/S0021-9673(01)87651-2

Bontemps, J., Philippe, P., Bettendorff, L., Lombet, J., Dandrifosse, G., Schoffeniels, E., & Crommen, J. (1984). Determination of thiamine and thiamine phosphates in excitable tissues as thiochrome derivatives by reversed phase high-performance liquid chromatography on octadecyl-silica. Journal of Chromatography. Biomedical Applications, 307, 283-294. doi:10.1016/S0378-4347(00)84100-6

Crommen, J., & Herné, P. (1984). Indirect Uv Detection of Hydrophilic Ionized Compounds in Reversed-Phase Liquid Chromatography by Use of a Uv-Absorbing Ion of the Same Charge. Journal of Pharmaceutical and Biomedical Analysis, 2 (2), 241-53. doi:10.1016/0731-7085(84)80075-8