Publications and communications of Grégory Ehx

Articles accepted in reviewed journal

C. Ritacco, M. C. Köse, J. Courtois, L. Canti, C. Beguin, S. DUBOIS, B. Vandenhove et al. "Post-transplant cyclophosphamide prevents xenogeneic graft-versus-host disease while depleting proliferating regulatory T cells." iScience, 26, no. 3 (17 March 2023): 106085. doi:10.1016/j.isci.2023.106085
* These authors have contributed equally to this work.

L. Canti, K. K. Ariën, I. Desombere, S. Humblet-Baron, P. Pannus, L. Heyndrickx, A. HENRY et al. "Antibody response against SARS-CoV-2 Delta and Omicron variants after third-dose BNT162b2 vaccination in allo-HCT recipients." Cancer Cell, 40, no. 4 (11 April 2022): 335-337. doi:10.1016/j.ccell.2022.02.005

L. Canti* , S. Humblet-Baron* , I. Desombere, J. Neumann, P. Pannus, L. Heyndrickx, A. Henry et al. "Predictors of neutralizing antibody response to BNT162b2 vaccination in allogeneic hematopoietic stem cell transplant recipients." Journal of hematology & oncology, 14, no. 1 (2021): 174. doi:10.1186/s13045-021-01190-3
* These authors have contributed equally to this work.

J. Courtois, C. Ritacco, S. DUBOIS, L. Canti, B. Vandenhove, L. SEIDEL, C. Daulne et al. "Itacitinib prevents xenogeneic GVHD in humanized mice." Bone Marrow Transplantation, 56 (2021): 2672-2681. doi:10.1038/s41409-021-01363-1

G. Ehx* , C. Ritacco* , M. HANNON, S. DUBOIS, L. Delens, E. WILLEMS, S. SERVAIS, P. Drion, Y. BEGUIN, and F. Baron. "Comprehensive analysis of the immunomodulatory effects of rapamycin on human T cells in graft-versus-host disease prophylaxis." American Journal of Transplantation, 21 (2021): 2662-2674. doi:10.1111/ajt.16505
* These authors have contributed equally to this work.

C. Ritacco* , G. Ehx* , C. GREGOIRE, C. Daulne, E. WILLEMS, S. SERVAIS, Y. BEGUIN, and F. Baron. "High proportion of terminally-differentiated regulatory T cells after allogeneic hematopoietic stem cell transplantation." Bone Marrow Transplantation, 56 (2021): 1828-1841. doi:10.1038/s41409-021-01221-0
* These authors have contributed equally to this work.

A. Bolomsky, M. Vogler, M. C. Köse, C. A. Heckman, G. Ehx, H. Ludwig, and J. Caers. "MCL-1 inhibitors, fast-lane development of a new class of anti-cancer agents." Journal of hematology & oncology, 13, no. 1 (2020): 173. doi:10.1186/s13045-020-01007-9

L. Delens, G. Ehx, J. SOMJA, L. Vrancken, L. Belle, L. SEIDEL, C. Grégoire et al. "In Vitro Th17-Polarized Human CD4(+) T Cells Exacerbate Xenogeneic Graft-versus-Host Disease." Biology of Blood and Marrow Transplantation, 25 (2019): 204-215. doi:10.1016/j.bbmt.2018.10.007

C. Grégoire, C. Ritacco, M. Hannon, L. SEIDEL, L. Delens, L. Belle, S. DUBOIS et al. "Comparison of Mesenchymal Stromal Cells From Different Origins for the Treatment of Graft-vs.-Host-Disease in a Humanized Mouse Model." Frontiers in Immunology, 10 (2019): 619. doi:10.3389/fimmu.2019.00619

G. Ehx, J. SOMJA, H.-J. Warnatz, C. Ritacco, M. HANNON, L. Delens, G. Fransolet et al. "Xenogeneic graft-versus-host disease in humanized NSG and NSG-HLA-A2/HHD mice." Frontiers in Immunology, 9 (2018): 1943. doi:10.3389/fimmu.2018.01943

G. Ehx, G. Fransolet, L. De Leval, S. D'Hondt, S. Lucas, M. Hannon, L. Delens et al. "Azacytidine prevents experimental xenogeneic graft-versus-host disease without abrogating graft-versus-leukemia effects." Oncoimmunology (2017): 6:e1314425. doi:10.1080/2162402X.2017.1314425

L. Belle* , G. Fransolet* , J. Somja, M. BINSFELD, P. Delvenne, P. Drion, M. Hannon, Y. BEGUIN, G. Ehx* , and F. Baron*. "Limited Impact of Imatinib in a Murine Model of Sclerodermatous Chronic Graft-versus-Host Disease." PLoS ONE, 11 (12 December 2016): 0167997. doi:10.1371/journal.pone.0167997
* These authors have contributed equally to this work.

G. Fransolet* , G. Ehx* , J. SOMJA, L. Delens, M. Hannon, J. Muller, S. DUBOIS et al. "Azacytidine mitigates experimental sclerodermic chronic graft-versus-host disease." Journal of Hematology and Oncology, 9 (04 July 2016): 53. doi:10.1186/s13045-016-0281-2
* These authors have contributed equally to this work.

S. SERVAIS, Y. BEGUIN, L. Delens, G. Ehx, G. Fransolet, M. Hannon, E. WILLEMS, S. Humblet-Baron, L. Belle, and F. Baron. "Novel approaches for preventing acute graftversus- host disease after allogeneic hematopoietic stem cell transplantation." Expert Opinion on Investigational Drugs, 9 (11 May 2016): 957-972. doi:10.1080/13543784.2016.1182498

S. Göktuna, K. Shostak, T.-L. Chau, L. Heukamp, B. Hennuy, H. Q. Duong, A. LADANG et al. "The Prosurvival IKK-Related Kinase IKK« Integrates LPS and IL17A Signaling Cascades to Promote Wnt-Dependent Tumor Development in the Intestine." Cancer Research, 76 (2016): 2587-99. doi:10.1158/0008-5472.CAN-15-1473

M. HANNON, Y. BEGUIN, G. Ehx, S. SERVAIS, L. SEIDEL, C. Graux, J. Maertens et al. "Immune Recovery after Allogeneic Hematopoietic Stem Cell Transplantation following Flu-TBI versus TLI-ATG Conditioning." Clinical Cancer Research, 21, no. 14 (15 July 2015): 3131-9. doi:10.1158/1078-0432.CCR-14-3374

G. Ehx* , M. Hannon* , Y. BEGUIN, S. Humblet-Baron* , and F. BARON*. "Validation of a multicolor staining to monitor phosphoSTAT5 levels in regulatory T-cell subsets." Oncotarget, 6 (2015): 43255-43266. doi:10.18632/oncotarget.6486
* These authors have contributed equally to this work.

G. Ehx* , S. Gerin* , G. Mathy, F. Franck, H. C. Oliveira, A. E. Vercesi, and F. Sluse. "Liver proteomic response to hypertriglyceridemia in human-apolipoprotein C-III transgenic mice at cellular and mitochondrial compartment levels." Lipids in Health and Disease, 13 (21 July 2014): 116. doi:10.1186/1476-511X-13-116
* These authors have contributed equally to this work.

F. Baron, S. Humblet-Baron, G. Ehx, S. SERVAIS, M. HANNON, L. Belle, C. LECHANTEUR et al. "Thinking out of the box - New approaches to controlling GVHD." Current Hematologic Malignancy Reports, 9 (2014): 73-84. doi:10.1007/s11899-013-0187-9

Articles accepted in conference proceedings

M. V. Ruiz, A. Apavaloaei, Q. Zhao, M.-P. Hardy, S. Lemieux, C. Perreault, and G. Ehx. "BamQuery: A new proteogenomic tool to explore the immunopeptidome and validate tumor‐specific antigens." European Journal of Immunology, 51, S1 (August 2021): 60. doi:10.1002/eji.202170200

Oral presentations in conferences with scientific selection committee

C. Beguin, O. Kwan, C. Ritacco, J.-C. Debray, E. Dejardin, S. Dubois, M. C. Köse et al. "TNF-α priming of human regulatory T cells does not increase their ability to prevent xenogeneic graft-versus-host disease." Paper presented at Congrès annuel de la Société Francophone de Greffe de Moelle et Thérapie Cellulaire, Lille, France, 17 November 2023.

Preprints

M. V. Ruiz Cuevas, M.-P. Hardy, J.-D. Larouche, A. Apavaloaei, E. Kina, K. Vincent, P. Gendron et al. "BamQuery: a proteogenomic tool for the genome-wide exploration of the immunopeptidome." Eprint/Working Paper, United States: Cold Spring Harbor Laboratory, 2022. https://orbi.uliege.be2268/298884. doi:10.1101/2022.10.07.510944
* These authors have contributed equally to this work.