Gullo, C.* , Laverdeur, E.* , Dancre, M., Peiffer, R., Boumahd, Y., Agirman, F., Maloujahmoum, N., Désiront, L., Thiry, M., Rademaker, G., Bellahcene, A., & Peulen, O. (28 November 2025). Focal adhesion assembly and cell migration require myoferlin in PDAC cell lines. Scientific Reports, 15 (1). doi:10.1038/s41598-025-27134-2 * These authors have contributed equally to this work. |
Peiffer, R., Laverdeur, E., Gaigneaux, A., Boumahd, Y., Gullo, C., Rademaker, G., Crake, R., Lavergne, A., Maloujahmoum, N., Agirman, F., Herfs, M., Masamune, A., Letellier, E., Bellahcene, A., & Peulen, O. (2025). Targeting myoferlin in ER/Golgi vesicle trafficking reprograms pancreatic cancer-associated fibroblasts. EMBO Journal. doi:10.1038/s44318-025-00570-6 |
Rademaker, G., Hernandez, G. A., Seo, Y., Dahal, S., Miller-Phillips, L., Li, A. L., Peng, X. L., Luan, C., Qiu, L., Liégeois, M., Wang, B., Wen, K. W., Kim, G. E., Collisson, E. A., Kruger, S. F., Boeck, S., Ormanns, S., Guenther, M., Heinemann, V., ... Perera, R. M. (2025). PCSK9 drives sterol-dependent metastatic organ choice in pancreatic cancer. Nature. doi:10.1038/s41586-025-09017-8 |
Jain, A., Heremans, I., Rademaker, G., Detomasi, T. C., Rohweder, P., Anderson, D., Zhang, J., Hernandez, G. A., Gupta, S., von Linde, T., Lange, M., Spacci, M., Luo, J., Citron, Y. R., Olzmann, J. A., Dawson, D. W., Craik, C. S., Bommer, G., Perera, R. M., & Zoncu, R. (28 March 2025). Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins. Science, 387 (6741), 8331. doi:10.1126/science.adq8331 |
Rademaker, G., Costanza, B., Bellier, J., Herfs, M., Peiffer, R., Agirman, F., Maloujahmoum, N., Habraken, Y., Delvenne, P., Bellahcene, A., Castronovo, V., & Peulen, O. (02 March 2023). Correction: Human colon cancer cells highly express myoferlin to maintain a fit mitochondrial network and escape p53-driven apoptosis. Oncogenesis, 12 (1), 11. doi:10.1038/s41389-023-00455-5 |
Lemaitre, F.* , Chakrama, F.* , O'Grady, T., Peulen, O., Rademaker, G., Deward, A., Chabot, B., Piette, J., Colige, A., Lambert, C., Dequiedt, F.* , & Habraken, Y.*. (09 December 2022). The transcription factor c-Jun inhibits RBM39 to reprogram pre-mRNA splicing during genotoxic stress. Nucleic Acids Research, 50 (22), 12768 - 12789. doi:10.1093/nar/gkac1130 * These authors have contributed equally to this work. |
Rademaker, G.* , Boumahd, Y.* , Peiffer, R., Anania, S., Wissocq, T., Liégeois, M., Luis, G., Sounni, N. E., Agirman, F., Maloujahmoum, N., De Tullio, P., Thiry, M., Bellahcene, A., Castronovo, V., & Peulen, O. (July 2022). Myoferlin targeting triggers mitophagy and primes ferroptosis in pancreatic cancer cells. Redox Biology, 53, 102324. doi:10.1016/j.redox.2022.102324 * These authors have contributed equally to this work. |
Boumahd, Y., Rademaker, G., Peiffer, R., Anania, S., Agirman, F., Maloujahmoum, N., Bellahcene, A., & Peulen, O. (22 June 2022). Myoferlin targeting triggers mitophagy and primes ferroptosis in pancreatic cancer cells [Poster presentation]. EACR 2022. |
Rademaker, G., Costanza, B., Pyr Dit Ruys, S., Peiffer, R., Agirman, F., Maloujahmoum, N., Vertommen, D., Turtoi, A., Bellahcene, A., Castronovo, V.* , & Peulen, O.*. (2022). Paladin, overexpressed in colon cancer, is required for actin polymerisation and liver metastasis dissemination. Oncogenesis, 11, 42. doi:10.1038/s41389-022-00416-4 * These authors have contributed equally to this work. |
Dumont, E., De Bleye, C., Rademaker, G., Coic, L., Horne, J., Sacre, P.-Y., Peulen, O., Hubert, P., & Ziemons, E. (01 March 2021). Development of a prototype device for near real-time surface-enhanced Raman scattering monitoring of biological samples. Talanta, 224, 121866. doi:10.1016/j.talanta.2020.121866 |
Anania, S., Peiffer, R., Rademaker, G., Hego, A., Thiry, M., Deldicque, L., Francaux, M., Maloujahmoum, N., Agirman, F., Bellahcene, A., Castronovo, V., & Peulen, O. (21 June 2020). Myoferlin is a yet unknown interactor of the mitochondrial dynamics’ machinery in pancreas cancer cells. Cancers, 12 (6), 1643. doi:10.3390/cancers12061643 |
Bellier, J., Nokin, M.-J., Caprasse, M., Tiamiou, A., Blomme, A., Scheijen, J. L., KOOPMANSCH, B., MacKay, G. M., Chiavarina, B., Costanza, B., Rademaker, G., Durieux, F., Agirman, F., Maloujahmoum, N., Cusumano, P. G., LOVINFOSSE, P., Leung, H. Y., LAMBERT, F., Bours, V., ... Bellahcene, A. (04 February 2020). Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab. Cell Reports, 30 (5), 1400-1416.e6. doi:10.1016/j.celrep.2020.01.012 |
Anania, S., Rademaker, G., Peiffer, R., Hego, A., Deldicque, L., Maloujahmoum, N., Agirman, F., Bellahcene, A., Castronovo, V., & Peulen, O. (February 2020). Role of myoferlin in mitochondrial dynamics and metabolic fitness of pancreas cancer [Poster presentation]. BACR Annual Meeting 2020 - Cancer metastases: from bedside to bench, Brussels, Belgium. |
Anania, S., Rademaker, G., Bellahcene, A., Castronovo, V., & Peulen, O. (December 2019). Role of myoferlin in mitochondrial dynamics and metabolic fitness of Pancreatic Ductal Adenocarcinoma [Poster presentation]. Second CIRM Scientific Day, Liège, Belgium. |
Rademaker, G., Costanza, B., Bellier, J., Herfs, M., Agirman, F., Maloujahmoum, N., Bellahcene, A., Castronovo, V., & Peulen, O. (26 November 2019). Myoferlin depletion induces DNA damage response and p53- dependent cell cycle arrest and apoptosis in colon cancer [Poster presentation]. Metabolism in Cancer and Stromal Cells (2nd edition), Leuven, Belgium. |
Rademaker, G., Costanza, B., Anania, S., Agirman, F., Maloujahmoum, N., Bellahcene, A., Castronovo, V., & Peulen, O. (23 October 2019). Myoferlin Contributes to the Metastatic Phenotype of Pancreatic Cancer Cells by Enhancing Their Migratory Capacity Through the Control of Oxidative Phosphorylation [Poster presentation]. Pancreatic Cancer Symposium, Toulouse, France. |
Anania, S., Rademaker, G., Wissocq, T., Bellahcene, A., Castronovo, V., & Peulen, O. (October 2019). Role of myoferlin in mitochondrial dynamics and metabolic fitness of PDAC [Poster presentation]. PANCREATIC CANCER SYMPOSIUM, Toulouse, France. |
Costanza, B., Rademaker, G., Turtoi, A., Bellahcene, A., Castronovo, V., & Peulen, O. (October 2019). TGFBI, an ECM interacting protein, enhances glycolysis and promotes pancreatic cancer cell migration [Poster presentation]. Pancreatic Cancer Symposium 2019, Toulouse, France. |
Anania, S., Rademaker, G., Wissocq, T., Bellahcene, A., Castronovo, V., & Peulen, O. (06 September 2019). Role of myoferlin in mitochondrial dynamics and metabolic fitness of pancreas cancer [Poster presentation]. EDT Cancerology 2019, Bruxelles, Belgium. |
Peulen, O., Rademaker, G., Anania, S., Turtoi, A., Bellahcene, A., & Castronovo, V. (August 2019). Ferlin overview: from membrane to cancer biology. Cells, 8, 954. doi:10.3390/cells8090954 |
Rademaker, G., Costanza, B., Anania, S., Agirman, F., Maloujahmoum, N., Bellahcene, A., Castronovo, V., & Peulen, O. (13 June 2019). Myoferlin Contributes to the Metastatic Phenotype of Pancreatic Cancer Cells by Enhancing Their Migratory Capacity Through the Control of Oxidative Phosphorylation [Poster presentation]. Belgian Society for Cell and Developmental Biology - Spring Meeting, Liège, Belgium. |
Rademaker, G., Costanza, B., Anania, S., Agirman, F., Maloujahmoum, N., Di Valentin, E., Goval, J.-J., Bellahcene, A., Castronovo, V., & Peulen, O. (June 2019). Myoferlin contributes to the metastatic phenotype of pancreatic cancer cells by enhancing their migratory capacity through the control of oxidative phosphorylation. Cancers, 11 (6). doi:10.3390/cancers11060853 |
Costanza, B., Rademaker, G., Tiamiou, A., De Tullio, P., Leenders, J., Blomme, A., Bellier, J., Bianchi, E., Turtoi, A., Delvenne, P., Bellahcene, A., Peulen, O.* , & Castronovo, V.*. (2019). TGFBI, an ECM interacting protein, enhances glycolysis and promotes pancreatic cancer cell migration. International Journal of Cancer. doi:10.1002/ijc.32247 * These authors have contributed equally to this work. |
Nokin, M.-J., Bellier, J., Durieux, F., Peulen, O., Rademaker, G., Gabriel, M., Monseur, C., CHARLOTEAUX, B., Verbeke, L., van Laere, S., RONCARATI, P., Herfs, M., Lambert, C., Scheijen, J., Schalkwijk, C., Colige, A., Caers, J., Delvenne, P., Turtoi, A., ... Bellahcene, A. (2019). Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer. Breast Cancer Research, 21(1, 11. doi:10.1186/s13058-018-1095-7 |
Rademaker, G., Costanza, B., Bellier, J., Herfs, M., Peiffer, R., Agirman, F., Maloujahmoum, N., Habraken, Y., Delvenne, P., Bellahcene, A., Castronovo, V.* , & Peulen, O.*. (2019). Human colon cancer cells highly express myoferlin to maintain a fit mitochondrial network and escape p53-driven apoptosis. Oncogenesis. doi:10.1038/s41389-019-0130-6 * These authors have contributed equally to this work. |
Rademaker, G., Hennequière, V., Nokin, M.-J., LOVINFOSSE, P., Durieux, F., GOFFLOT, S., Bellier, J., Costanza, B., Herfs, M., Peiffer, R., Bettendorff, L., Deroanne, C., Thiry, M., Delvenne, P., Hustinx, R., Bellahcene, A., Castronovo, V., & Peulen, O. (April 2018). Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness. Oncogene, 37 ((32)), 4398-4412. doi:10.1038/s41388-018-0287-z |