Meliadis, C., Obata, Y., Bons, J., Müller, L., Schurman, C., Sieverts, M., Achinuq, B., Pedrinazzi, E., Blouin, S., Angel, P., Schilling, B., Ruffoni, D., Acevedo, C., Gilbert, P., & Alliston, T. (05 September 2025). Tonotopic Control of Cochlear Bone Quality by Osteocytes [Paper presentation]. ASBMR 2025 Annual Meeting, Seattle, United States - Washington. |
Cantamessa, A., Blouin, S., Rummler, M., Berzlanovich, A., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (2025). The mineralization of osteonal cement line depends on where the osteon is formed. JBMR Plus. doi:10.1093/jbmrpl/ziaf114 |
Sensini, A., Raimondi, L., Malerba, A., Silva, C. P., Tits, A., Di Lorenzo, A., Ruffoni, D., Blouin, S., Hartmann, M. A., Zucchelli, A., van Griensven, M., & Moroni, L. (08 July 2025). MORPHO-MECHANICS OF THE SHEEP CALCANEAL ENTHESIS AS A RELEVANT ANIMAL MODEL FOR TISSUE ENGINEERING [Paper presentation]. 30th Congress of the European Society of Biomechanics. |
Demeuldre, L.* , Cantamessa, A.* , Blouin, S., Rummler, M., Berzlanovich, A., Weinkamer, R., Hartmann, M., & Ruffoni, D. (2025). Exploring lacunocanalicular network specificity along the cement line in human osteons. Bone and Joint. doi:10.1302/1358-992X.2025.6.021 * These authors have contributed equally to this work. |
Gaillard, V., Malerba, A., Lefevre, G., Blouin, S., Van Lenthe, G. H., Weinkamer, R., Hartmann, M., & Ruffoni, D. (16 June 2025). Characterization of the osteocyte lacunocanalicular network in subchondral bone of healthy mice [Paper presentation]. 33rd Annual Meeting of the European Orthopaedic Research Society, Davos, Switzerland. |
Pedrinazzi, E., Blouin, S., Hego, A., Simar, A., Hartmann, M., & Ruffoni, D. (16 June 2025). The Role of Mineral Heterogeneity, Trabecular Orientation, and Collagen Fibers Arrangement on Tissue-Level Trabecular Bone Mechanics [Paper presentation]. 33rd Annual Meeting of the European Orthopaedic Research Society (EORS), Davos, Switzerland. |
Pedrinazzi, E., Blouin, S., Hego, A., Simar, A., Hartmann, M., & Ruffoni, D. (16 June 2025). The Role of Mineral Heterogeneity, Trabecular Orientation, and Collagen Fibers Arrangement on Tissue-Level Trabecular Bone Mechanics [Paper presentation]. 33rd Annual Meeting of the European Orthopaedic Research Society (EORS), Davos, Switzerland. |
Sensini, A., Raimondi, L., Malerba, A., Silva, C. P., Zucchelli, A., Tits, A., Ruffoni, D., Blouin, S., Hartmann, M. A., van Griensven, M., & Moroni, L. (17 April 2025). Understanding the structure and mechanics of the sheep calcaneal enthesis: a relevant animal model to design scaffolds for tissue engineering applications. Biomaterials advances, 175, 214320. doi:10.1016/j.bioadv.2025.214320 |
Malerba, A., Gaillard, V., Blouin, S., Dall'Ara, E., van Lenthe, H., Hartmann, M., & Ruffoni, D. (31 March 2025). CHARACTERIZATION OF THE OSTEOCHONDRAL INTERFACE IN YOUNG HEALTHY MICE [Paper presentation]. 30th Congress of the European Society of Biomechanics, Zurich, Switzerland. |
Souhail, H., Zamengo, E., D'Andrea, L., Blouin, S., Hartmann, M., Vena, P., & Ruffoni, D. (2025). THE MECHANICAL INTERPLAY BETWEEN BONE AND SCAFFOLD MICROSTRUCTURES – A COMPUTATIONAL ANALYSIS [Paper presentation]. 30th Congress of the European Society of Biomechanics, Zurich, Switzerland. |
Souhail, H., Zamengo, E., D'Andrea, L., Blouin, S., Hartmann, M., Vena, P., & Ruffoni, D. (2025). THE MECHANICAL INTERPLAY BETWEEN BONE AND SCAFFOLD MICROSTRUCTURES -A COMPUTATIONAL ANALYSIS [Paper presentation]. 30th Congress of the European Society of Biomechanics, Zurich, Switzerland. |
Grossman, Q., Lê Maureen, D'Andrea Luca, Gastaldi D., Vena Pascale, & Ruffoni, D. (05 December 2024). Tuning the mechanical properties of architectured materials: from sandwich beams to triply periodic minimal surface composite lattices [Paper presentation]. 1st International Conference on Bio-Joining 2024, Porto, Portugal. |
Volders, T., Contino, M., Passoni, F., Andena, L., & Ruffoni, D. (05 December 2024). Interface Thickness and Orientation in 3D Printed Fiber-Reinforced Composites [Paper presentation]. 1st International Conference on Bio-joining, Porto, Portugal. |
Cantamessa, A., Blouin, S., Rummler, M., Berzlanovich, A., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (2024). The mineralization of osteonal cement line depends on where the osteon is formed. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/324040. doi:10.1101/2024.10.06.616843 |
Müller, L., Ska, M., Piyush Uniyal, G. Harry van Lenthe, & Ruffoni, D. (11 September 2024). Microstructural and micromechanical analysis of proximal tibia in aging rats [Paper presentation]. XXIII International Conference on Mechanics in Medicine and Biology, Bruxelles, Belgium. |
Cantamessa, A., Schemenz, V., Blouin, S., Amini, S., Rummler, M., Berzlanovich, A., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (September 2024). Exploring Material, Mechanical and Biological Features of Cement Lines in Human Osteons [Paper presentation]. XXIII International Conference on Mechanics in Medicine and Biology. |
Gaillard, V., Tits, A., Plougonven, E., Dall'Ara, E., & Ruffoni, D. (03 July 2024). Trabecular Architecture in Human Calcaneus Bone and Functional Adaptation to Tendon Insertion [Paper presentation]. 29th Congress of the European Society of Biomechanics, Édimbourg, United Kingdom. |
Müller, L., Stéphane Blouin, Drion, P., Markus A. Hartmann, & Ruffoni, D. (03 July 2024). Changes in Mineral Content and Mechanical Properties of Calcified Cartilage in the Knee during Aging [Paper presentation]. 29th Congress of the European Society of Biomechanics, Edinburgh, United Kingdom. |
Pedrinazzi, E., Blouin, S., Pyka, G., Béché, A., Hartmann, M., Simar, A., & Ruffoni, D. (02 July 2024). THE ROLE OF MINERAL HETEROGENEITY AND MATERIAL ANISOTROPY ON TRABECULAR BONE MECHANICS [Paper presentation]. 29th Congress of the European Society of Biomechanics, Edinburgh, United Kingdom. |
Cantamessa, A., Schemenz, V., Blouin, S., Amini, S., Rummler, M., Berzlanovich, A., Weinkamer, R., Wagermaier, W., Hartmann, M., & Ruffoni, D. (July 2024). Cement lines material properties and interplay with the lacuna-canalicular network in human osteonal bone [Paper presentation]. European Society of Biomechanics, Edimbourg, United Kingdom. |
Malerba, A., Tits, A., Volders, T., Vena, P., & Ruffoni, D. (July 2024). DO STIFFNESS GRADIENTS PLAY A ROLE IN THE PROTECTION OF THE TENDON-TO-BONE INTERFACE? A COMPUTATIONAL STUDY [Poster presentation]. 29th Congress of the European Society of Biomechanics, Edinburgh, United Kingdom. |
Cantamessa, A., Blouin, S., Amini, S., Rummler, M., Berzlanovich, A., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (16 November 2023). Mineralization and Mechanical Insights of Cement Lines in Human Osteonal Bone [Paper presentation]. Annual Benelux meeting of IEEE Engineering in Medicine and Biology Society and 21st National Day of Biomedical Engineering, Bruxelles, Belgium. |
Cantamessa, A., Blouin, S., Amini, S., Rummler, M., Berzlanovich, A., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (13 October 2023). A Multimodal Analysis of Cement Lines in Human Osteonal Bone [Poster presentation]. Annual Meeting of the American Society of Bone and Mineral Research, Vancouver, Canada. |
Tits, A., Blouin, S., Rummler, M., Kaux, J.-F., Drion, P., van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (August 2023). Structural and functional heterogeneity of mineralized fibrocartilage at the Achilles tendon-bone insertion. Acta Biomaterialia, 166, 409 - 418. doi:10.1016/j.actbio.2023.04.018 |
Cantamessa, A., Blouin, S., Amini, S., Rummler, M., Berzlanovich, A., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (27 July 2023). Mineral Content and Mechanical Properties of Cement Lines in Human Osteonal Bone [Paper presentation]. European Society of Biomechanics Conference, Maastricht, Netherlands. |
Volders, T., Zorzetto, L., Razi, H., Weinkamer, R., & Ruffoni, D. (12 July 2023). Damage propagation in osteon-inspired structures: the role of the cement line [Poster presentation]. 28th Congress of the European Society of Biomechanics, Maastricht, Netherlands. |
Müller, L., Tits, A., Weinkamer, R., Drion, P., Dall'Ara, E., Van Lenthe, G. H., & Ruffoni, D. (10 July 2023). Changes in subchondral bone microstructure and shape with age in tibial knee [Paper presentation]. 28th Congress of the European Society of Biomechanics, Maastricht, Netherlands. |
Lew, A. J., Stifler, C. A., Tits, A., Schmidt, C. A., Scholl, A., Cantamessa, A., Müller, L., Delaunois, Y., Compère, P., Ruffoni, D., Buehler, M. J., & Gilbert, P. U. P. A. (July 2023). A Molecular-Scale Understanding of Misorientation Toughening in Corals and Seashells. Advanced Materials, 35 (28), 2300373. doi:10.1002/adma.202300373 |
Gattin, M., Bochud, N., Rosi, G., Grossman, Q., Ruffoni, D., & Naili, S. (May 2023). Ultrasonic bandgaps in viscoelastic 1D-periodic media: Mechanical modeling and experimental validation. Ultrasonics, 131, 106951. doi:10.1016/j.ultras.2023.106951 |
Tits, A., Blouin, S., Rummler, M., Kaux, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (31 March 2023). Bone-fibrocartilage crosstalk and osteocyte lacuno-canalicular network at the tendon-bone insertion [Paper presentation]. European Society of Biomechanics Conference, Maastricht, Netherlands. |
Delaunois, Y., Tits, A., Grossman, Q., Smeets, S., Malherbe, C., Eppe, G., van Lenthe, G. H., Ruffoni, D.* , & Compère, P.*. (2023). Design Strategies of the Mantis Shrimp Spike: How the Crustacean Cuticle Became a Remarkable Biological Harpoon? Natural Sciences. doi:10.22541/au.167199666.61851387/v1 * These authors have contributed equally to this work. |
Saldívar, M. C., Salehi, S., Veeger, R. P. E., Fenu, M., Cantamessa, A., Klimopoulou, M., Talò, G., Moretti, M., Lopa, S., Ruffoni, D., van Osch, G. J. V. M., Fratila-Apachitei, L. E., Doubrovski, E. L., Mirzaali, M. J., & Zadpoor, A. A. (2023). Rational positioning of 3D printed micro-bricks to realize high-fidelity, multi-functional soft-hard interfaces. Cell Reports. Physical Science. doi:10.1101/2023.01.21.525002 |
Malerba, A., Tits, A., Volders, T., Vena, P., & Ruffoni, D. (2023). A COMPUTATIONAL INVESTIGATION OF THE TENDON-TO-BONE INSERTION: THE ROLE OF TISSUE ANISOTROPY [Paper presentation]. 28th Congress of the European Society of Biomechanics, Maastricht, Netherlands. |
Grossman, Q., Varga, P., & Ruffoni, D. (25 October 2022). Architectured Interfaces in Bimaterial Attachments [Paper presentation]. Workshop of the IRP Coss&Vita, Metamaterials and biomechanics : from bio-inspiration to bio-metamaterials, Arpino, Italy. |
Volders, T., Zorzetto, L., Razi, H., Weinkamer, R., & Ruffoni, D. (28 September 2022). Designing Architectured Materials with Tunable Damage Behavior Inspired by Osteonal Bone [Poster presentation]. Imparting Intelligence in and Through Self-Learning Materials and Structures, Ventura, United States - California. |
Gattin, M., Bochud, N., Rosi, G., Grossman, Q., Ruffoni, D., & Naili, S. (23 September 2022). Ultrasound characterization of the viscoelastic properties of additively manufactured photopolymer materials. Journal of the Acoustical Society of America, 152 (3), 1901-1912. doi:10.1121/10.0014180 |
Volders, T., Zorzetto, L., Razi Hajar, Weinkamer Richard, & Ruffoni, D. (03 August 2022). How to protect a weak spot inside a load-bearing architecture material: a lesson from bone [Paper presentation]. WCCM-APCOM Yokohama 2022, 15th World Congress on Computational Mechanics & 8th Asian Pacific Congress on Computational Mechanics, Yokohama, Japan. |
Cantamessa, A., Muraro, P., Delaunois, Y., Compère, P., Blouin, S., Hartmann, M. A., & Ruffoni, D. (27 June 2022). Mineral content and biomechanical properties of fibrolamellar bone [Paper presentation]. European Society of Biomechanics Conference, Porto, Portugal. |
Habets, T., Siragusa, F., Müller, A. J., Grossman, Q., Ruffoni, D., Grignard, B., & Detrembleur, C. (07 June 2022). Facile construction of functional poly(monothiocarbonate) copolymers under mild operating conditions. Polymer Chemistry, 13 (21), 3076-3090. doi:10.1039/d2py00307d |
De Noni, L., Zorzetto, L., Briatico-Vangosa, F., Rink, M., Ruffoni, D., & Andena, L. (April 2022). Modelling the interphase of 3D printed photo-cured polymers. Composites. Part B, Engineering, 234, 109737. doi:10.1016/j.compositesb.2022.109737 |
Aghaei, A., Bochud, N., Rosi, G., Grossman, Q., Ruffoni, D., & Naili, S. (March 2022). Ultrasound characterization of bioinspired functionally graded soft-to-hard composites: Experiment and modeling. Journal of the Acoustical Society of America, 151 (3), 1490. doi:10.1121/10.0009630 |
Müller, L., Tits, A., Plougonven, E., Drion, P., Dall'Ara, E., Léonard, A., Van Lenthe, H., & Ruffoni, D. (2022). Architecture of the trabecular bone between the metaphyseal and subchondral parts in the knee joint [Paper presentation]. 20th National Day of Biomedical Engineering, Bruxelles, Belgium. |
Müller, L., Tits, A., Plougonven, E., Drion, P., Dall'Ara, E., Van Lenthe, G. H., & Ruffoni, D. (2022). Differences between subchondral and trabecular bone microporosities beneath the bone-cartilage interface at the knee joint [Poster presentation]. 15th Congress of the International Society of Bone Morphometry, Odense, Denmark. |
Grossman, Q., Varga, P., & Ruffoni, D. (29 December 2021). Voxel 3D printing and computer simulations to prototype bimaterial attachments based on local interface patterning [Paper presentation]. 2021 MRS Fall Meeting, Boston, United States - Massachusetts. |
Tits, A., Plougonven, E., Blouin, S., Hartmann, M. A., Kaux, J.-F., Drion, P., Fernandez, J., van Lenthe, G. H., & Ruffoni, D. (August 2021). Local anisotropy in mineralized fibrocartilage and subchondral bone beneath the tendon-bone interface. Scientific Reports, 11, 16534. doi:10.1038/s41598-021-95917-4 |
Tits, A., & Ruffoni, D. (2021). Joining soft tissues to bone: Insights from modeling and simulations. Bone Reports. doi:10.1016/j.bonr.2020.100742 |
Tits, A., Varga, P., Volders, T., Kaux, J.-F., Plougonven, E., Fernandez, J., Drion, P., Van Lenthe, G. H., & Ruffoni, D. (October 2020). Local adaptation of bone micro-structure and canal network to tendon insertion investigated by image-based micro-FE simulations. Bone Reports, 13, 100392. doi:10.1016/j.bonr.2020.100393 |
Tits, A., Varga, P., KAUX, J.-F., Plougonven, E., Fernandez, J., Drion, P., Van Lenthe, G. H., & Ruffoni, D. (24 June 2020). Soft-to-hard biological interfaces: microstructural and micromechanical investigation of the tendon-bone attachment [Paper presentation]. European Calcified Tissue Society Digital Masterclass. |
Zorzetto, L., Andena, L., Briatico-Vangosa, F., De Noni, L., Thomassin, J.-M., Jérôme, C., Grossman, Q., Mertens, A., Weinkamer, R., Rink, M., & Ruffoni, D. (2020). Properties and role of interfaces in multimaterial 3D printed composites. Scientific Reports, 10 (1), 22285. doi:10.1038/s41598-020-79230-0 |
Ruffoni, D. (12 September 2018). Mechanical Properties of Interfaces in 3D Printed Polymer Composites Investigated by Nanoindentation [Paper presentation]. Indentation 2018, Liege, Belgium. |
Ruffoni, D. (28 June 2018). 3D Printing of Bio-inspired Helical Composites with Enhanced Failure Resistance [Paper presentation]. First International Conference on Materials, Mimicking, Manufacturing from and for Bio Application. |
Zorzetto, L., & Ruffoni, D. (22 September 2017). Mimicking helicoidal biological materials to improve strength of synthetic composites [Paper presentation]. European Congress and Exhibition on Advanced Materials and Processes 2017 - Euromat2017, Thessaloniki, Greece. |
Li, Z., Betts, D., Kuhn, G., Müller, R., & Ruffoni, D. (2017). Mechanical loading therapy increases bone formation while reducing bone resorption following implantation in a mouse model of postmenopausal osteoporosis. JBMR Plus. |
Li, Z., Kuhn, G., Schirmer, M., Müller, R., & Ruffoni, D. (2017). Impaired bone formation in ovariectomized mice reduces implant integration as indicated by longitudinal in vivo micro-computed tomography. PLoS ONE, 12 (9), 1-22. doi:10.1371/journal.pone.0184835 |
Li, Z., Müller, R., & Ruffoni, D. (2017). Bone remodeling and mechanobiology around implants: Insights from small animal imaging. Journal of Orthopaedic Research. doi:10.1002/jor.23758 |
Zorzetto, L., Briatico Vangosa, F., Rink, M., Andena, L., & Ruffoni, D. (2017). A multiscale analysis of interface properties in 3D printed composites [Paper presentation]. European Congress and Exhibition on Advanced Materials and Processes. |
Zorzetto, L., & Ruffoni, D. (September 2015). Remarkable stiffness enhancement in multilayered honeycombs obtained through periodic variations in Poisson's ratio [Paper presentation]. Euromat2015, Warsaw, Poland. |
Ruffoni, D., Christen, P., Scherf, H., & Weinkamer, R. (April 2015). Wolff’s Law and the Interplay between Bone Structure and External Loading. BoneKEy Reports, 13. doi:10.1038/bonekey.2015.40 |
Schulte, F. A., Ruffoni, D., Lambers, F. M., Christen, D., Webster, D. J., Kuhn, G., & Mueller, R. (2013). Local Mechanical Stimuli Regulate Bone Formation and Resorption in Mice at the Tissue Level. PLoS ONE, 8 (4), 62172-12. doi:10.1371/journal.pone.0062172 |
Ruffoni, D. (2007). Modeling of material and architectural quality of trabecular bone [Doctoral thesis, Max Planck Institute of Colloids and Interfaces]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/196635 |