Publications and communications of Maria Artesi

Mouraux, C., Aktan, D., Artesi, M., Ewenczyk, C., Durr, A., Coarelli, G., & Depierreux, F. (April 2026). Déterminer la phase des variants : trois méthodes illustrées dans les NBIA atypiques liées au gène PLA2G6. Revue Neurologique, 182, 66-S67. doi:10.1016/j.neurol.2026.01.194

Karpe, S. D., Artesi, M., Wayet, J., Durkin, K., Hahaut, V., Uchimaru, K., Makiyama, J., Iwanaga, M., Utsunomiya, A., Kolijn, P. M., Langerak, A. W., Burny, A., Marçais, A., Hermine, O., Watanabe, T., Georges, M., & Van den Broeke, A. (November 2025). A viral clonality evenness score to predict progression to adult T-cell leukaemia in asymptomatic carriers of human T-lymphotropic virus type 1 in Japan: a retrospective longitudinal cohort study. The Lancet Microbe, 6 (11), 101198. doi:10.1016/j.lanmic.2025.101198

Mouraux, C., FOUQUET, C., Durkin, K., Dideberg, V., Bulk, S., Aktan, D., Artesi, M., & Depierreux, F. (27 October 2025). Homozygous Pathogenic MYH3 Variants Associated With Arthrogryposis and Lingual Dystonia. Tremor and Other Hyperkinetic Movements, 15, 53. doi:10.5334/tohm.1079

Grentzinger, V., PALMEIRA, L., Durkin, K., Artesi, M., & Bours, V. (22 July 2025). Lifting the veil on Challenging Medically Relevant Genes [Poster presentation]. Intelligent Systems for Molecular Biology/European Conference on Computational Biology (ISMB/ECCB), Liverpool, United Kingdom.

Grentzinger, V., PALMEIRA, L., Durkin, K., Artesi, M., & Bours, V. (20 July 2025). Lifting the veil on Challenging Medically Relevant Genes [Paper presentation]. Intelligent Systems for Molecular Biology/European Conference on Computational Biology (ISMB/ECCB), Liverpool, United Kingdom.

Grentzinger, V., PALMEIRA, L., Durkin, K., Artesi, M., & Bours, V. (06 July 2025). Lifting the veil on Challenging Medically Relevant Filaggrin Gene [Poster presentation]. Journées Ouvertes en Biologie, Informatique et Mathématiques - JOBIM 2025, Bordeaux, France.

Grentzinger, V., PALMEIRA, L., Durkin, K., Artesi, M., & Bours, V. (07 May 2025). Lifting the veil on Challenging Medically Relevant Genes [Paper presentation]. International Symposium on Human Genomics, Paris, France.

Grentzinger, V., PALMEIRA, L., Durkin, K., Artesi, M., CHARLOTEAUX, B., Dideberg, V., & Bours, V. (07 May 2025). A Needle in a Haystack: Improving Genetic Analysis of Challenging Medically Relevant MUC1 Gene [Poster presentation]. International Symposium on Human Genomics, Paris, France.

Freire, M. V., Thissen, R., Martin, M., Fasquelle, C., HELOU, L., Durkin, K., Artesi, M., Lumaka, A., LEROI, N., Segers, K., DEBERG, M., Gatot, J.-S., Habran, L., Palmeira, L., Josse, C., & Bours, V. (January 2025). Genetic evaluation of patients with multiple primary cancers. Oncology Letters, 29 (1), 4. doi:10.3892/ol.2024.14750

Grentzinger, V., Artesi, M., Palmeira, L., Durkin, K., & Bours, V. (15 November 2024). Waiting on the Dark Side of the Moon: Novel Variable Number Tandem Repeat Alleles of Medically Relevant FLG Gene discovered by using Long-Read Sequencing [Poster presentation]. SFMBBM PhD Day 2024, Namur, Belgium.

Grentzinger, V., Artesi, M., Palmeira, L., Dideberg, V., Olivier, S., Bours, V., & Durkin, K. (24 April 2024). Hidden in Plain Sight: Homologous Recombination masks Filaggrin Alleles of Potential Clinical Significance [Poster presentation]. byteMAL 2024, Maastricht, Netherlands.

Tang, L., Swedlund, B., Dupont, S., Harland, C., Costa Monteiro Moreira, G., Durkin, K., Artesi, M., Mullaart, E., Sartelet, A., Karim, L., Coppieters, W., Georges, M., & Charlier, C. (09 March 2024). GWAS reveals determinants of mobilization rate and dynamics of an active endogenous retrovirus of cattle. Nature Communications, 15 (1), 2154. doi:10.1038/s41467-024-46434-1

El Moussaoui, M., Bontems, S., Meex, C., Hayette, M.-P., LEJEUNE, M., Hong, S. L., Dellicour, S., Moutschen, M., CAMBISANO, N., Renotte, N., Bours, V., Darcis, G., Artesi, M.* , & Durkin, K.*. (04 March 2024). Intrahost evolution leading to distinct lineages in the upper and lower respiratory tracts during SARS-CoV-2 prolonged infection. Virus Evolution, 10 (1), 073. doi:10.1093/ve/veae073
* These authors have contributed equally to this work.

Grentzinger, V., Durkin, K. W., Palmeira, L., Artesi, M., Olivier, S., & Bours, V. (24 November 2023). Identification of novel haplotypes within the challenging medically relevant FLG gene [Poster presentation]. SFMBBM PhD Day, Liège, Belgium.

Kremer, C., Torneri, A., Libin, P. J. K., Meex, C., Hayette, M.-P., Bontems, S., Durkin, K. W., Artesi, M., Bours, V., Lemey, P., Darcis, G., Hens, N., & Meuris, C. (16 June 2023). Reconstruction of SARS-CoV-2 outbreaks in a primary school using epidemiological and genomic data. Epidemics, 44, 100701. doi:10.1016/j.epidem.2023.100701

Grentzinger, V., GRISART, B., Meynsbrughen, M., Artesi, M., Palmeira, L., Dideberg, V., CHARLOTEAUX, B., Durkin, K. W., Brysse, A., & Bours, V. (25 May 2023). Detecting pathogenic variants in chronic kidney disease using long-read sequencing [Paper presentation]. Annual Meeting @ Living Tomorrow Vilvoorde, Vilvoorde, Belgium.

El Moussaoui, M., Maes, N., Hong, S. L., Lambert, N., Gofflot, S., DELLOT, P., Belhadj, Y., Huynen, P., Hayette, M.-P., Meex, C., Bontems, S., Defêche, J., Godderis, L., Molenberghs, G., Meuris, C., Artesi, M., Durkin, K., Rahmouni, S., GREGOIRE, C., ... DARCIS, G. (14 June 2022). Evaluation of Screening Program and Phylogenetic Analysis of SARS-CoV-2 Infections among Hospital Healthcare Workers in Liège, Belgium. Viruses, 14 (6), 1302. doi:10.3390/v14061302

Thissen, R., ARTESI, M., Durkin, K., JOSSE, C., PALMEIRA, L., & BOURS, V. (24 December 2021). Comprehensive detection of homologous recombination deficiency by Nanopore sequencing [Poster presentation]. GIGA cancer day, Liège, Belgium.

Durkin, K., Artesi, M., VAN DEN BROEKE, A., Bours, V., Hahaut, V., & Georges, M. (21 June 2021). Pooled crispr inverse pcr sequencing (pcip-seq): simultaneous sequencing of viral insertion points and the integrated viral genomes with long reads.

Van Campenhout, C., De Mendonça, R., Alexiou, B., De Clercq, S., Racu, M.-L., Royer-Chardon, C., Rusu, S., Van Eycken, M., ARTESI, M., Durkin, K., Mardulyn, P., BOURS, V., Decaestecker, C., Remmelink, M., Salmon, I., & D'Haene, N. (2021). Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Genome Sequencing from Post-Mortem Formalin-Fixed, Paraffin-Embedded Lung Tissues. The Journal of Molecular Diagnostics. doi:10.1016/j.jmoldx.2021.05.016

Artesi, M.* , Hahaut, V.* , Cole, B.* , Lambrechts, L., Ashrafi, F., Marçais, A., Hermine, O., Griebel, P., Arsic, N., van der Meer, F., Burny, A., Bron, D., BIANCHI, E., DELVENNE, P., BOURS, V., Charlier, C., Georges, M., Vandekerckhove, L.* , Van den Broeke, A.* , & Durkin, K.*. (2021). PCIP-seq: simultaneous sequencing of integrated viral genomes and their integration sites with long reads. Genome Biology, 22, 97. doi:10.1186/s13059-021-02307-0
* These authors have contributed equally to this work.

Bollen, N., Artesi, M., Durkin, K., Hong, S. L., Potter, B., Boujemla, B., Vanmechelen, B., Martí-Carreras, J., Wawina-Bokalanga, T., Meex, C., Bontems, S., Hayette, M.-P., André, E., Maes, P., Bours, V., Baele, G., & Dellicour, S. (2021). Exploiting genomic surveillance to map the spatio-temporal dispersal of SARS-CoV-2 spike mutations in Belgium across 2020. Scientific Reports, 11 (1), 18580. doi:10.1038/s41598-021-97667-9

Butera, Y., Mukantwari, E., Artesi, M., Umuringa, J. D. A., O'Toole, Á. N., Hill, V., Rooke, S., Hong, S. L., Dellicour, S., Majyambere, O., Bontems, S., Boujemla, B., Quick, J., Resende, P. C., Loman, N., Umumararungu, E., Kabanda, A., Murindahabi, M. M., Tuyisenge, P., ... Rujeni, N.*. (2021). Genomic sequencing of SARS-CoV-2 in Rwanda reveals the importance of incoming travelers on lineage diversity. Nature Communications, 12 (1), 5705. doi:10.1038/s41467-021-25985-7
* These authors have contributed equally to this work.

Dellicour, S., Durkin, K., Hong, S., Vanmechelen, B., Marti-Carreras, J., Gill, M., Meex, C., Bontems, S., André, E., Gilbert, M., Walker, C., De Maio, N., Hadfield, J., Hayette, M.-P., Bours, V., Wawina-Bokalanga, T., Artesi, M., Baele, G., Maes, P., & Faria, N. R. (2021). A phylodynamic workflow to rapidly gain insights into the dispersal history and dynamics of SARS-CoV-2 lineages. Molecular Biology and Evolution. doi:10.1093/molbev/msaa284

Maclot, F., Bontems, S., Meex, C., Artesi, M., Beckers, P., Bours, V., Durkin, K., & Hayette, M.-P. (2021). Development of a multiplex RT-qPCR using the drop out strategy to screen the SARS-CoV-2 South African 501Y.V2 variant. Journal of Infection, 83 (1), 19-e21. doi:10.1016/j.jinf.2021.04.035

Marçais, A., Lhermite, L., Artesi, M., Laurent, C., Durkin, K., Hahaut, V., Rosewick, N., Suarez, F., Sibon, D., Cheminant, M., Avettand-Fenoël, V., Bruneau, J., Georges, M., Pique, C., Van den Broeke, A.* , Asnafi, V.* , & Hermine, O.*. (2021). Targeted deep sequencing reveals clonal and subclonal mutational signatures in Adult T-cell leukemia/lymphoma and defines an unfavorable indolent subtype. Leukemia, 35, 764-776. doi:10.1038/s41375-020-0900-3
* These authors have contributed equally to this work.

Meuris, C., Kremer, C., Geerinck, A., Locquet, M., Bruyère, O., Defêche, J., Meex, C., Hayette, M.-P., Duchene, L., Dellot, P., Azarzar, S., Maréchal, N., Sauvage, A.-S., Frippiat, F., Giot, J.-B., Léonard, P., Fombellida, K., Moutschen, M., Durkin, K., ... Darcis, G. (2021). Transmission of SARS-CoV-2 After COVID-19 Screening and Mitigation Measures for Primary School Children Attending School in Liège, Belgium. JAMA Network Open, 4 (10), 2128757. doi:10.1001/jamanetworkopen.2021.28757

Rosewick, N.* , Hahaut, V.* , Durkin, K., Artesi, M., Karpe, S., Wayet, J., Griebel, P., Arsic, N., Marçais, A., Hermine, O., Burny, A., Georges, M., & Van den Broeke, A. (2020). An Improved Sequencing-Based Bioinformatics Pipeline to Track the Distribution and Clonal Architecture of Proviral Integration Sites. Frontiers in Microbiology, 11, 587306. doi:10.3389/fmicb.2020.587306
* These authors have contributed equally to this work.

Artesi, M., Hahaut, V., Ashrafi, F., Marcais, A., Hermine, O., Griebel, P., Arsic, N., van der Meer, F., Burny, A., Bron, D., Charlier, C., Georges, M., Van den Broeke, A., & Durkin, K. (2019). Pooled CRISPR Inverse PCR sequencing (PCIP-seq): simultaneous sequencing of retroviral insertion points and the associated provirus in thousands of cells with long reads 558130. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/237583. doi:10.1101/558130

Pérès, E., Blin, J., P. Ricci, E., Artesi, M., Hahaut, V., Van den Broeke, A., Corbin, A., Gazzolo, L., Ratner, L., Jalinot, P., & Duc Dodon, M. (2018). PDZ domain-binding motif of Tax sustains T-cell proliferation in HTLV-1-infected humanized mice. PLoS Pathogens. doi:10.1371/journal.ppat.1006933

Percher, F., Curis, C., Peres, E., Artesi, M., Rosewick, N., Jeannin, P., Gessain, A., Gout, O., Mahieux, R., Ceccaldi, P.-E., Van den Broeke, A., Duc Dodon, M., & Afonso, P. V. (22 June 2017). HTLV-1-induced leukotriene B4 secretion by T cells promotes T cell recruitment and virus propagation. Nature Communications, 8, 15890. doi:10.1038/ncomms15890

Rosewick, N.* , Durkin, K.* , Artesi, M.* , Marçais, A., Hahaut, V., Griebel, P., Avettand-Fenoel, V., Burny, A., Charlier, C., Hermine, O., Georges, M., & Van den Broeke, A. (23 May 2017). Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis. Nature Communications, 8. doi:10.1038/ncomms15264
* These authors have contributed equally to this work.

Artesi, M., Marcais, A., Durkin, K., Rosewick, N., Hahaut, V., Suarez, F., Trinquand, A., Lhermitte, L., Asnafi, V., Avettand-Fenoel, V., Burny, A., Georges, M., Hermine, O., & Van den Broeke, A. (2017). Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia, 31 (11), 2532-2535. doi:10.1038/leu.2017.260

Durkin, K., Rosewick, N., Artesi, M., Hahaut, V., Griebel, P., Arsic, N., Burny, A., Georges, M., & Van den Broeke, A. (2016). Characterization of novel Bovine Leukemia Virus (BLV) antisense transcripts by deep sequencing reveals constitutive expression in tumors and transcriptional interaction with viral microRNAs. Retrovirology, 13 (1), 33. doi:10.1186/s12977-016-0267-8

Durkin, K., Artesi, M., Rosewick, N., Marçais, A., Hermine, O., Georges, M., & Van den Broeke, A. (28 August 2015). Improving the methodology for the detection of proviral integration sites in the host genome via high throughput sequencing. Retrovirology, 12 (1).

Rosewick, N., Durkin, K., Marçais, A., Artesi, M., Hermine, O., Charlier, C., Georges, M., & Van den Broeke, A. (28 August 2015). HTLV-1/BLV antisense-RNA dependent host gene perturbation in pre-leukemic and leukemic clones. Retrovirology, 12 (1).

Robe, P., Martin, D., Nguyen-Khac, M.-T., Artesi, M., Deprez, M., Albert, A., Vanbelle, S., Califice, S., Bredel, M., & Bours, V. (2009). Early termination of ISRCTN45828668, a phase 1/2 prospective, randomized study of sulfasalazine for the treatment of progressing malignant gliomas in adults. BMC Cancer, 9, 372. doi:10.1186/1471-2407-9-372