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Article (Scientific journals)
Comparative ultrastructural study of the effects of serum-free medium and dibutyryl-cyclic AMP on newborn rat astroblasts.
Moonen, Gustave; Heinen, Ernst; Goessens, Guy
1976In Cell and Tissue Research, 167 (2), p. 221-7
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Keywords :
Animals; Animals, Newborn; Astrocytes/drug effects/ultrastructure; Blood; Bucladesine/pharmacology; Cell Adhesion/drug effects; Cell Differentiation/drug effects; Culture Media; Neuroglia/drug effects; Rats
Abstract :
[en] Modifications of cell shape induced in cultured newborn rat astroblasts by serum deprivation or dibutyryladenosine 3'-5' monophosphate (dBcAMP) are described. Serum suppression modifies the adhesitivity of the cells to the substrate, but this modification is not consistent with a true differentiation. The main ultrastructural feature of dBcAMP-treated astroblasts is the presence of an extensive system of 90 A microfilaments, while control cells are relatively devoid of these structures.
Disciplines :
Anatomy (cytology, histology, embryology...) & physiology
Author, co-author :
Moonen, Gustave  ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Heinen, Ernst ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Histologie humaine
Goessens, Guy ;  Université de Liège - ULiège > Services généraux (Faculté des sciences) > Relations académiques et scientifiques (Sciences)
Language :
English
Title :
Comparative ultrastructural study of the effects of serum-free medium and dibutyryl-cyclic AMP on newborn rat astroblasts.
Publication date :
1976
Journal title :
Cell and Tissue Research
ISSN :
0302-766X
eISSN :
1432-0878
Publisher :
Springer Science & Business Media B.V., New York, United States - New York
Volume :
167
Issue :
2
Pages :
221-7
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 22 September 2009

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