Reference : Comparative ultrastructural study of the effects of serum-free medium and dibutyryl-c...
Scientific journals : Article
Life sciences : Anatomy (cytology, histology, embryology...) & physiology
Comparative ultrastructural study of the effects of serum-free medium and dibutyryl-cyclic AMP on newborn rat astroblasts.
Moonen, Gustave mailto [Centre Hospitalier Universitaire de Liège - CHU > > Neurologie Sart Tilman >]
Heinen, Ernst mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Histologie humaine >]
Goessens, Guy mailto [Université de Liège - ULiège > Services généraux (Faculté des sciences) > Relations académiques et scientifiques (Sciences) >]
Cell and Tissue Research
Springer Science & Business Media B.V.
Yes (verified by ORBi)
New York
[en] Animals ; Animals, Newborn ; Astrocytes/drug effects/ultrastructure ; Blood ; Bucladesine/pharmacology ; Cell Adhesion/drug effects ; Cell Differentiation/drug effects ; Culture Media ; Neuroglia/drug effects ; Rats
[en] Modifications of cell shape induced in cultured newborn rat astroblasts by serum deprivation or dibutyryladenosine 3'-5' monophosphate (dBcAMP) are described. Serum suppression modifies the adhesitivity of the cells to the substrate, but this modification is not consistent with a true differentiation. The main ultrastructural feature of dBcAMP-treated astroblasts is the presence of an extensive system of 90 A microfilaments, while control cells are relatively devoid of these structures.

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