Poster (Scientific congresses and symposiums)
Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoïds in cannabis plant material
De Backer, Benjamin; Debrus, Benjamin; Lebrun, Pierre et al.
200947ème meeting de l'International Association of Forensic Toxicologists (TIAFT)
 

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Keywords :
HPLC; cannabis sativa; cannabinoids; THC; CBD; CBG
Abstract :
[en] GC is commonly used for the analysis of cannabis samples, e.g. in forensic chemistry. However, as this method is based on heating of the sample, acidic forms of cannabinoids are decarboxylated into their neutral counterparts. Converely, HPLC permits the determination of the original composition of plant cannabinoids by direct analysis. Several HPLC methods have been described in the literature, but most of them failed to separate efficiently all the cannabinoids or were not validated according to general guidelines. By use of an innovative methodology for modelling chromatographic responses, a simple and accurate HPLC/DAD method was develop
Research center :
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
De Backer, Benjamin ;  Université de Liège - ULiège > Département de pharmacie > Chimie toxicologique
Debrus, Benjamin ;  Université de Liège - ULiège > Département de pharmacie > Chimie analytique
Lebrun, Pierre ;  Université de Liège - ULiège > Département de pharmacie > Chimie analytique
Dubois, Nathalie ;  Université de Liège - ULiège > Toxicologie clinique
Hubert, Philippe  ;  Université de Liège - ULiège > Département de pharmacie > Chimie analytique
Charlier, Corinne  ;  Université de Liège - ULiège > Département de pharmacie > Chimie toxicologique
Language :
English
Title :
Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoïds in cannabis plant material
Publication date :
August 2009
Event name :
47ème meeting de l'International Association of Forensic Toxicologists (TIAFT)
Event place :
Genève, Switzerland
Event date :
23-27 août 2009
Audience :
International
Funders :
BELSPO - SPP Politique scientifique - Service Public Fédéral de Programmation Politique scientifique
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since 20 April 2010

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