Article (Scientific journals)
Effects of thirty elements on bone metabolism
DERMIENCE, Michael; Lognay, Georges; Mathieu, Françoise et al.
2015In Journal of Trace Elements in Medicine and Biology, (32), p. 86-106
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Keywords :
bone; bone metabolism; minerals; mineral deficiency; trace elements; heavy metals; osteoporosis
Abstract :
[en] The human skeleton, made of 206 bones, plays vital roles including supporting the body, protecting organs, enabling movement, and storing minerals. Bones are made of organic structures, intimately connected with an inorganic matrix produced by bone cells. Many elements are ubiquitous in our environment, and many impact bone metabolism. Most elements have antagonistic actions depending on concentration. Indeed, some elements are essential, others are deleterious, and many can be both. Several pathways mediate effects of element deficiencies or excesses on bone metabolism. This paper aims to identify all elements that impact bone health and explore the mechanisms by which they act. To date, this is the first time that the effects of thirty minerals on bone metabolism have been summarized.
Disciplines :
Endocrinology, metabolism & nutrition
Author, co-author :
DERMIENCE, Michael ;  Université de Liège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Analyse, qual. et risques - Labo. de Chimie analytique
Lognay, Georges ;  Université de Liège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Analyse, qual. et risques - Labo. de Chimie analytique
Mathieu, Françoise;  Kashin–Beck Disease Fund asbl-vzw
Goyens, Phillippe;  Free Universities of Brussels > Department and Laboratory of Pediatric
Language :
English
Title :
Effects of thirty elements on bone metabolism
Publication date :
2015
Journal title :
Journal of Trace Elements in Medicine and Biology
ISSN :
0946-672X
Publisher :
Gustav Fischer Verlag, Stuttgart, Germany
Issue :
32
Pages :
86-106
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 06 July 2015

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