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See detailIsolation and identification of anthropogenic particles in fish stomachs by Raman spectroscopy: a new method
Collard, France ULiege; Gilbert, Bernard ULiege; Eppe, Gauthier ULiege et al

in Organohalogen Compounds (2015, August)

Microplastic particles (MP) contaminate oceans and affect marine organisms in several ways. Ingestion combined with food intake is generally reported. However, data interpretation is often circumvented by ... [more ▼]

Microplastic particles (MP) contaminate oceans and affect marine organisms in several ways. Ingestion combined with food intake is generally reported. However, data interpretation is often circumvented by the difficulty to separate MP from bulk samples. Visual examination is often used as one or the only step to sort these particles. However, color, size and shape are insufficient and often unreliable criteria. Here we present an isolation method of MP specially adapted to a subsequent analysis by Raman spectroscopy. This method avoids fluorescence problems allowing the identification anthropogenic particles (AP) from stomach contents of fish by Raman spectroscopy. It was validated with commercial samples of microplastics and cotton along with stomach contents from three different Clupeiformes fishes: Clupea harengus, Sardina pilchardus and Engraulis encrasicolus. The optimized digestion and isolation protocol showed no visible impact on microplastics and cotton particles while the spectroscopic analysis allowed precise identification of microplastics and textile fibers. This approach allowed us to isolate 35 particles. These were analyzed by Raman spectroscopy: eleven were microplastics and thirteen were made of cellulose or lignin, or both (mostly fibers). Some particles were not identified but contained artificial colorants. This isolation protocol will help to assess the presence, quantity and composition of AP in planktivorous fish stomachs. [less ▲]

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See detailDynamique de l'espace architectural : force, vitesse, déplacement dans l'oeuvre de Le Corbusier
Steinmetz, Rudy ULiege

in Revue Philosophique de Louvain (2015, August), Tome 113(3), 425-447

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See detailComparison of 3 different variable selection strategies to improve the predictions of fatty acid profile in bovine milk by mid-infrared spectrometry
Soyeurt, Hélène ULiege; Brostaux, Yves ULiege; Dehareng, Frédéric et al

in Journal of Animal Science (2015, July 15), 93/98(Suppl. s3/ Suppl. 2), 804

Mid-infrared (MIR) spectrometry is used to provide phenotypes related to the milk composition. Foss spectrum contains 1,060 datapoints. The number of reference values required to build a calibration ... [more ▼]

Mid-infrared (MIR) spectrometry is used to provide phenotypes related to the milk composition. Foss spectrum contains 1,060 datapoints. The number of reference values required to build a calibration equation is often lower than the spectral variables mainly due to the cost of chemical analysis. Problems of collinearity and overfitting appear when this high dimensional data set is used. This research will study the interest of using variable selection (VS) approach before the use of partial least square regression (PLS). The data set included 1,236 milk spectra related to their fatty acid (FA) contents. Saturated (SFA), monounsaturated (MUFA), polyunsaturated (PUFA), short chain (SCFA), medium chain (MCFA), and long chain FA (LCFA) were studied. The data set was randomly divided in 3 groups which were used to create 3 calibration and validation data sets. Three different VS methods were compared. The first strategy was based on the part of trait variability explained by each considered variables (R2VS). The second method was based on the regression coefficient estimated after PLS procedure divided by the standard deviation of the considered spectral variable (BSVS). The third strategy permitted to underline the uninformative variables which were the ones having the lowest ratio of average regression coefficient to their corresponding standard deviation estimated after a leave-one out cross-validation (UVEVS). For UVEVS and BSVS, the cutoff was determined from the known uninformative region of MIR milk spectrum. The cutoff for R2VS was determined by testing different thresholds ranged between 5 and 40%. The most interesting cutoff for R2VS was 25%. The worst results in terms of validation root mean square error of prediction (RMSEPv) were obtained using a full PLS (i.e., without VS). The maximum difference (g/dl of milk) of RMSEPv obtained from the full PLS and from the PLS using selected variables were 0.156 for SFA, 0.139 for MUFA, 0.011 for PUFA, 0.025 for SCFA, 0.164 for MCFA, and 0.188 for LCFA. R2VS gave the best results for all studied traits followed by UVEVS and then BSVS. In conclusion, the use of VS improved significantly the performance of FA MIR equations. [less ▲]

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See detailCapitalizing on fine milk composition for breeding and management of dairy cows
Gengler, Nicolas ULiege; Soyeurt, Hélène ULiege; Dehareng, Frédéric et al

in Journal of Animal Science (2015, July 12), 93/ 98(Suppl. s3/ Suppl. 2), 4

Management and breeding of dairy cows face the challenge of permanently adapting to changing production circumstances under socioeconomic constraints. If management and breeding addresses different ... [more ▼]

Management and breeding of dairy cows face the challenge of permanently adapting to changing production circumstances under socioeconomic constraints. If management and breeding addresses different timeframes of action, both need relevant phenotypes that allow for precise monitoring of the status of the cows, their products (i.e., milk and subsequently dairy products), their behavior and their environmental impact. Milk composition has been identified as an important source of information since it could reflect, at least partially, all these elements. Major milk components such as fat, protein, urea, and lactose contents are routinely predicted by mid-infrared (MIR) spectrometry and have been widely used for these purposes. But, milk composition is much more complex and other components might be informative. Such new milk-based phenotypes should be considered given that they are cheap, rapidly obtained, usable on a large scale, robust and reliable. In a first approach, new phenotypes can be predicted from MIR spectra using classical prediction equation based techniques. This method was used successfully for many novel traits (e.g., fatty acids, lactoferrin, minerals, milk technological properties, citrate), that can then be useful for management and breeding purposes. An innovation was to consider the longitudinal nature of the relationship between the trait of interest and the MIR spectra (e.g., to predict methane from MIR). By avoiding intermediate steps, prediction errors can be minimized when traits of interest (e.g., ketosis) are predicted directly from MIR spectra. In a second approach, in an innovative manner, patterns detected by comparing observed from expected MIR spectra can be used directly. All these traits can then be used to define best practices, adjust feeding and health management, improve animal welfare, improve milk quality and limit environmental impact. Under the condition that MIR data are available on a large scale, phenotypes for these traits will allow genetic and genomic evaluations. Introduction of novel traits into the breeding objectives will need additional research to clarify socio-economic weights and genetic correlation with other traits of interest. [less ▲]

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See detailDo milk spectrometry phenotypes have a role to play in dairy fertility and health programs?
Bastin, Catherine ULiege; Theron, Léonard ULiege; Laine, Aurélie ULiege et al

in Journal of Animal Science (2015, July 12), 93/98(Suppl. s3/ Suppl. 2), 5

Genetic selection allows for permanent improvement of dairy cow fertility and health. However, these traits are generally complex, difficult to record, and lowly heritable (<0.10). Hence, indicators have ... [more ▼]

Genetic selection allows for permanent improvement of dairy cow fertility and health. However, these traits are generally complex, difficult to record, and lowly heritable (<0.10). Hence, indicators have been proven as useful in the prediction of genetic merit for direct fertility and health traits as long as they are easier to measure, heritable, and genetically correlated. Considering that changes in (fine) milk composition over the lactation reflects the physiological status of the cow, the mid-infrared (MIR) analysis of milk opens the door to a whole new range of potential indicator traits of fertility and health. Previous studies investigated the phenotypic and genetic relationships between fertility and MIR-predicted phenotypes, most of them being related to negative postpartum energy balance and body fat mobilization (e.g., fat to protein ratio, urea, fatty acids profile). Results showed that a combination of various fatty acids traits (e.g., C18:1 cis-9 and C10:0) could be used to improve fertility. Furthermore, occurrence of (sub-)clinical ketosis has been related to milk-based phenotypes such as fatty acids and ketone bodies. Hence, MIR-predicted acetone and β-hydroxybutyrate contents in milk were demonstrated as useful for breeding cows less susceptible to ketosis. Although studies investigating the genetic association among mastitis and MIR-predicted phenotypes are scarce, a wide range of traits, potentially predicted by MIR spectrometry, are worth considering. It includes traits related to the disease response of the cow (e.g., lactoferrin), to the reduced secretory activity (e.g., lactose) and to the alteration of blood-milk barrier (e.g., minerals, citrate). Moreover, direct MIR-prediction of fertility and health traits should be further considered. To conclude, MIR-predicted phenotypes have a role to play in the improvement of dairy cow fertility and health. However, further studies are warranted to (1) grasp underlying associations among MIR-predicted indicator and fitness traits, (2) estimate the genetic parameters, and (3) include these traits in broader breeding strategies. [less ▲]

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See detailInnovative Combination of all Sources of Information for Production Traits in Slovenian Brown Swiss
Vandenplas, J.; Spehar, M.; Potocnik, K. et al

in Interbull Bulletin (2015, July 09), 49

Slovenian Brown Swiss is a small population with genetic improvement based on its own breeding program supplemented with imports from other populations. Routine national genetic evaluations for milk, fat ... [more ▼]

Slovenian Brown Swiss is a small population with genetic improvement based on its own breeding program supplemented with imports from other populations. Routine national genetic evaluations for milk, fat, and protein yields are computed from all available national phenotypic and pedigree data. At an international level, a Multiple Across Country Evaluation (MACE) is performed by Interbull to aggregate estimated breeding values (EBV) for international sires across different populations into a single Slovenian ranking. Additionally, a genomic evaluation for many sires is now routinely computed at an international level through the InterGenomics (IG) project. Phenotypes used for this genomic evaluation are deregressed MACE EBV which generate genomically enhanced EBV (GEBV) for all genotyped sires. However, national evaluations are not influenced by these international evaluations and, therefore, may be less accurate and even biased because foreign data used to select foreign sires are not used at the national level. Therefore, an integration of international evaluations back into the national evaluations is required to use the available information in an optimal way for both bulls and cows. The aim of this study was to assess the potential of an innovative Bayesian approach, based on a single-step genomic Best Linear Unbiased Prediction, that combines national data for milk, fat and protein yields with the IG genotypes and information (i.e., GEBV and reliabilities). Because IG information considers genotypes and also MACE information, which also includes national information, double-counting of contributions due to records and due to relationships had to be considered. The integration of IG genotypes and information showed an increase of reliability for the three traits, especially for all IG sires. For example, for IG sires with progeny with national records, the integration led to an average increase of reliability of > 0.10 points for milk yield, in comparison to their average national reliability. For the IG sires without progeny with national records, an average increase of reliability of >0.74 points was observed for the same trait. An average increase of reliability of > 0.05 points was also observed for animals with a reliability <0.30 and sired by genotyped IG sires and with progeny with records. Finally, this approach has the potential to simultaneously combine national data and IG genotypes and information. Furthermore, while it was not implemented in this study, this approach has the advantage to allow the consideration of genotypes of other non-IG animals (e.g., cows). [less ▲]

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See detailANALYSE DES PHÉNOMÈNES CLIMATIQUES EXTRÊMES DANS LE SUD-EST DU NIGER
Karimou Barké, Mahamadou Salifou ULiege

in Publications de l'Association Internationale de Climatologie (2015, July 01), 28

The climate of the Department of Goure and Maine Soroa(Southeast of Niger) is of the saharo-sahelian’s type. Extreme climatic events are isolated weather phenomena, which coincide in space and time to ... [more ▼]

The climate of the Department of Goure and Maine Soroa(Southeast of Niger) is of the saharo-sahelian’s type. Extreme climatic events are isolated weather phenomena, which coincide in space and time to affect agricultural production, livestock breeding and natural resource stocks. In order to qualify and quantify regionally climate extremes, the statistical tool used is the extreme value distribution according to the Gumbel’s law. The results show that the occurrence of warm days and nights tends to increase while cool nights decreases. [less ▲]

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See detailIntergenerational physical activity: Effects of a three-month intervention bringing together older adults and elementary school children
Mouton, Alexandre ULiege; Renier, Tom ULiege; Cloes, Marc ULiege

in Revista Espaňola de Educación Física y Deportes (2015, July), 410-S

For the first time in history, children are projected to have a shorter life expectancy than their parents (Olshansky et al., 2005). Besides, older adults are the less active population group (Sun et al ... [more ▼]

For the first time in history, children are projected to have a shorter life expectancy than their parents (Olshansky et al., 2005). Besides, older adults are the less active population group (Sun et al., 2013). Intergenerational PA has the potential to increase PA and quality of life (QoL) among those two age-groups but research in the field is still very limited (Flora & Faulkner, 2007). Accordingly, the aim of this study was to examine the impact of an intergeneration PA intervention on self-reported PA and Qol among older adults and elementary school children. At baseline, two intergenerational groups were formed: (Gr1) 11 older adults (63.91±7.62 years) and a class of 18 children (4.81±0.37 years); (Gr2) 9 older adults (68.67±7.25) and a class of 13 children (7.16±0.38years). Those groups took part in a three-month intergenerational intervention including one weekly session of PA practiced in the school context. Assessments were performed before (T0), during (satisfaction level), after the intervention (T1) and after a three months’ follow-up period (T2). PA and Qol were respectively assessed with the QAPPA and the SF-36 among older adults, and with adapted versions of the PAQ-C and the AUQUEI among children. Older adults’ physical fitness was also assessed with the SFT battery test. Participation rate was relatively high in both groups during PA sessions (Gr1: 81.48% older adults and 93.21% children; Gr2: 83.33% older adults and 91.45% children). At T1, Only 1 older adult (Gr1) dropped out of the study, as 9 children (group 1) and 6 children (group 2) dropped out due to the failure of the parents to complete and return the children’s questionnaires. Preliminary results of the SFT exposed significant improvements of the upper limbs strength in both groups (p<0.05). Further analyses will inform about effects on PA and Qol. [less ▲]

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See detailHow to determine the place provided to physical activity in a primary school? An attempt to identify objective variables
Mouton, Alexandre ULiege; Boone, Pauline; Cloes, Marc ULiege

in Revista Espaňola de Educación Física y Deportes (2015, July), 410-S

In the fight against sedentariness, recent meta analyses underlined the determining role of school as a foundation for physical activity (PA) promotion in children and adolescents (Biddle et al. 2012 ... [more ▼]

In the fight against sedentariness, recent meta analyses underlined the determining role of school as a foundation for physical activity (PA) promotion in children and adolescents (Biddle et al. 2012). Consequently, active schools projects are implemented worldwide.. They combine actions on several parallel axes with the physical education (PE) teacher as a corner stone. One of the challenges of such interventions is to follow the modifications and measure their effects. Moreover, it seems that practitioners and researchers still need an instrument to ascertain the real place provided to PA in a school. The aim of this presentation consists in describing the development, validation and testing of an instrument designed to provide such feedback. This study respects a qualitative approach and, by its step by step process, could be considered as an action research approach. Its main goal is to produce an audit instrument rather than providing data. Five successive steps were designed: Analysis of the literature in order to select the main dimensions to analyze; Development of a provisional tool based on objective items; Pilot study; Validation by a group of 13 experts; Testing of the final version in a school. The analysis was focused on the school policy and involved the principal, the PE teacher and the classroom teachers. 335 items were identified and spread across six dimensions. The experts underlined the validity and completeness of the instrument. For the practitioners, participating to the data collection is a means to become aware of what the school (should) propose. This study points out the large range of variables involved in the development of a PA school project, and bring forward the limitation of an assessment using objective data. It underlines that an audit process contributes to a more relevant perception of the reality. Practitioners would also be interested by an easier-to-use tool. [less ▲]

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See detail« 11bouge » website: Implementation of the content by a physical education teacher
Cloes, Marc ULiege; Pauly, Aurore; Mouton, Alexandre ULiege et al

in Revista Espaňola de Educación Física y Deportes (2015, July), 410-S

The decrease in physical activity (PA) and the rising of the inactivity rate are real social problems and affect many young people. Physical education (PE) teachers seem resourceless and do not know how ... [more ▼]

The decrease in physical activity (PA) and the rising of the inactivity rate are real social problems and affect many young people. Physical education (PE) teachers seem resourceless and do not know how to handle with it. Nowadays, some initiatives aiming to promote PE within the school are developed. The "11bouge" website (http://www.11bouge.be/index.php) was developed in this perspective by a mutual insurance company. The goal of the presentation is to analyze the implementation of the resources proposed in the website by one PE teacher. [less ▲]

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See detailExpectations and needs for training of instructors of a physical activity program for cancer survivors
Rompen, Jérôme ULiege; Korycki, Marta ULiege; Cloes, Marc ULiege

in Revista Espaňola de Educación Física y Deportes (2015, July), 410-S

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See detailSport pedagogy in the fitness sector: Introductory issue
Cloes, Marc ULiege

in Revista Espaňola de Educación Física y Deportes (2015, July), 410-S

The fitness sector is an important field among the leisure industry and represents a determining environment where people can increase their physical activity. Most of the research focusing on this ... [more ▼]

The fitness sector is an important field among the leisure industry and represents a determining environment where people can increase their physical activity. Most of the research focusing on this activity deals with biomedical aspects even if the teaching-learning process should take a central place. This symposium will continue the AIESEP's efforts to underline the need of developing specific pedagogical research on fitness as a follow up of the specialist seminar organized in Timisoara (Romania) in November 2014. [less ▲]

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See detailSport pedagogy in the fitness sector: A promising research topic?
Cloes, Marc ULiege; Franco, Susana; Simões, Vera et al

in Revista Espaňola de Educación Física y Deportes (2015, July), 410-S

During the symposium, after an introduction underlining the link between AIESEP’s objectives and the enhancement of the interest of sport pedagogy in the active leisure sector (M. Cloes), there will be an ... [more ▼]

During the symposium, after an introduction underlining the link between AIESEP’s objectives and the enhancement of the interest of sport pedagogy in the active leisure sector (M. Cloes), there will be an overview of the current research on teaching in fitness (S. Franco) and the critical analysis of a fitness instructor bachelor program (V. Simões). Finally, we will summary the research recommendations stated during the AIESEP Specialist Seminar held in Timisoara, Romania, in November 2014 (M. Onofre). Participants will be invited to comment and enrich the proposals. [less ▲]

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See detailSchool- and community-based PE & HEPA networks for daily physical activities
Naul, Roland; Cloes, Marc ULiege

in Revista Espaňola de Educación Física y Deportes (2015, July), 410-S

A selected collection of international and European based reviews and reviews of reviews on PE and on school based PA intervention studies (focused on Cochrane Systematic Reviews between 2007 and 2015 ... [more ▼]

A selected collection of international and European based reviews and reviews of reviews on PE and on school based PA intervention studies (focused on Cochrane Systematic Reviews between 2007 and 2015) will be analyzed according their design of intervention components (single PE /PA component vs. multiple-components) and sector interventions (single school-based vs. cross-sectoral setting approach). Reviews and meta-analysis show effectiveness of different factors, however with ambiguity, if minutes of PE at school and/or for extra-curricular time of PA are extended.The linkage of PE with other components of an active lifestyle and the extension of the school setting with other stakeholder moves on the Public Health Agenda and can achieve an evidence-based outcome of health-related benefits of PE at school. [less ▲]

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See detailQuality and Innovation, key factors for laboratory evolution
HUYNEN, Pascale ULiege

in Clinical Chemistry & Laboratory Medicine (2015, June 23)

Today the laboratory has to face many challenges: constant increase of number of tests to be run, private labs that competes in reaching a lower TAT, disease outbreak that arises without the possibility ... [more ▼]

Today the laboratory has to face many challenges: constant increase of number of tests to be run, private labs that competes in reaching a lower TAT, disease outbreak that arises without the possibility of human control, like the recent mumps outbreak, the need to provide fast results in case of emergency or for transplants, the request to keep high level of traceability of all results, the accreditation of the lab are just some examples. With the same number of operators, year after year, new clinical needs have to be satisfied in a timely manner, with efficiency and without compromise in quality. The solution for us has been, across several year, to look for innovation. Moving from Elisa to chemiluminescence and therefore from open systems to close and state of the art systems, it has allowed us to face with success all those challenges. The availability of more and more infectious disease markers on fully automated analyzers, with good level of performance, have let us to cope with all the changes that have happened across more than a decade. Indeed innovation and quality are fundamental to support properly the laboratory evolution that occurred since today and it is still occurring. Innovation in our laboratory it is also represented by the introduction of automatized tests not only on serum and plasma specimens, but also on CSF (for Lyme disease diagnosis) and on stool matrix. In 2013 in fact we have introduced, among the assays already tested in our laboratory, two assays performed on this matrix, the C. difficile Toxin A&B and GDH, due to the possibility offered by the LIAISON® systems to run all of them on the same serology platform, without crosscontamination. New markers will be available in the near future, and our laboratory will be always able to meet the next clinical needs. [less ▲]

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See detailLiminarité, métadiscours, et théâtre voltairien
Daubercies, Laurence ULiege

in Revue Voltaire (2015, June 12)

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See detailOxidative stress or not in healthy older subjects?
PINCEMAIL, Joël ULiege; CHRISTELBACH, Sophie ULiege; RICOUR, Céline ULiege et al

in OCC2015 (2015, June)

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See detailMethod and Tools for an Objective Approach of White Dwarf Asteroseismology
Charpinet, S.; Giammichele, N.; Brassard, P. et al

in Astronomical Society of the Pacific Conference Series (2015, June), 493

Stellar oscillation modes propagate deep inside stars and carry on information potentially allowing us to reconstruct, through asteroseismology, parts of their internal structure and dynamics. We present ... [more ▼]

Stellar oscillation modes propagate deep inside stars and carry on information potentially allowing us to reconstruct, through asteroseismology, parts of their internal structure and dynamics. We present and discuss here our strategy and tools developed to exploit objectively this potential for pulsating white dwarf stars. Our approach relies on a multimodal optimization technique aimed at identifying all potential seismic model solutions that best match the observed periods of a given star. This approach doesn't rely on model grids (hence avoiding their limitations) and makes use of static stellar structures of white dwarf stars as opposed to evolutionary models. The use of parameterized static models is a deliberate choice in this context and is aimed at approaching as closely as possible the real structure of the star as it is observed and probed by the detected oscillation modes without interferences from unavoidable model uncertainties propagated through billion years of evolution. We argue that this strategy is more likely to produce new tight constraints on the internal structure of white dwarf stars from which evolutionary models could be improved. [less ▲]

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See detailNeuronal excitation/inhibition balance is set by the need for sleep and the biological clock
Phillips, Christophe ULiege; Chellappa, Sarah Laxhmi ULiege; Ly, Julien et al

in NeuroImage (2015, June)

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See detailA First Look at the Nonadiabatic Properties of Pulsating Accreting White Dwarfs of the GW Lib Type
Van Grootel, Valérie ULiege; Fontaine, G.; Brassard, P. et al

in Astronomical Society of the Pacific Conference Series (2015, June), 493

We present results of a detailed stability survey of the pulsation properties of accreting white dwarfs of the GW Lib type. This is based on several state-of-the- art white dwarf evolutionary sequences ... [more ▼]

We present results of a detailed stability survey of the pulsation properties of accreting white dwarfs of the GW Lib type. This is based on several state-of-the- art white dwarf evolutionary sequences with varying envelope compositions, from pure hydrogen to pure helium. Using the same tools as in Van Grootel et al. (2013), where we have presented the first consistent view of the ZZ Ceti instability strip, we have mapped the GW Lib instability strip over the effective temperature-surface gravity plane, and as a function of envelope composition. We find that the location of the GW Lib instability domain is a strong and continuous function of the assumed envelope composition. We can accomodate all of the known GW Lib pulsators in various strips according to their atmospheric compositions. [less ▲]

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See detailThe Instability Strip of ZZ Ceti White Dwarfs
Van Grootel, Valérie ULiege; Fontaine, G.; Brassard, P. et al

in Astronomical Society of the Pacific Conference Series (2015, June), 493

The determination of the location of the theoretical ZZ Ceti instability strip in the log g − Teff diagram has remained a challenge over the years, due to the lack of a suitable treatment for convection ... [more ▼]

The determination of the location of the theoretical ZZ Ceti instability strip in the log g − Teff diagram has remained a challenge over the years, due to the lack of a suitable treatment for convection in these stars. We report here a detailed stability survey over the whole ZZ Ceti regime, including the low and extremely low masses. We computed to this aim 29 evolutionary sequences of DA models with various masses, chemical layering, and core compositions. These models are characterized by the so- called ML2/α=1.0 convective efficiency and take into account the important feedback effect of convection on the atmospheric structure. We computed pulsation spectra for these models with the Liège nonadiabatic pulsation code MAD, which is the only one to conveniently incorporate a full time-dependent convection treatment and, thus, provides the best available description of the blue edge of the instability strip. On the other hand, given the failure of all nonadiabatic codes to account properly for the red edge of the strip, including MAD, we tested the idea that the red edge is due to energy leakage through the atmosphere. Using this approach, we found that our theoretical ZZ Ceti instability strip accounts remarkably well for the boundaries of the empirical strip. [less ▲]

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See detailEvaluation d'une trousse de dépistage de l'éthylène glycol par méthode enzymatique
DEVILLE, Marine ULiege; HALENG, Jeanine ULiege; Henrad, Valérie et al

in Toxicologie Analytique et Clinique (2015, June), S27(2), 60-61

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See detailEstimation du délai entre la consommation d'héroïne et le prélèvement de sang chez des consommateurs chroniques
DUBOIS, Nathalie ULiege; Charlier, Corinne ULiege

in Toxicologie Analytique & Clinique (2015, June), S27(2), 43

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See detailDevelopment of a full fiber-coupled laser ultrasound robotic system using two-wave mixing 1064 nm detection and 532 nm YAG generation
Vandenrijt, Jean-François ULiege; Simar, Juan Felipe ULiege; Thizy, Cédric ULiege et al

in Laser Ultrasonics and Advanced Sensing (2015, June)

An all-fibered laser ultrasonic system for complex shape composite parts is presented. It is based on two-wave mixing detection and a long pulse laser working at 1064 nm and generation by a fibered YAG Q ... [more ▼]

An all-fibered laser ultrasonic system for complex shape composite parts is presented. It is based on two-wave mixing detection and a long pulse laser working at 1064 nm and generation by a fibered YAG Q-switch laser working at 532 nm. A compact optical head combining both beams is interfaced to a robot system for scanning. Some practical issues of this system are studied. [less ▲]

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See detailHigh-speed Photometric Observations of ZZ Ceti White Dwarf Candidates
Green, E.M.; Limoges, M.-M.; Gianninas, A. et al

in Astronomical Society of the Pacific Conference Series (2015, June), 493

We present high-speed photometric observations of ZZ Ceti white dwarf candidates drawn from the spectroscopic survey of bright DA stars from the Villanova White Dwarf Catalog by Gianninas et al., and from ... [more ▼]

We present high-speed photometric observations of ZZ Ceti white dwarf candidates drawn from the spectroscopic survey of bright DA stars from the Villanova White Dwarf Catalog by Gianninas et al., and from the recent spectroscopic survey of white dwarfs within 40 parsecs of the Sun by Limoges et al. We report the discovery of six new ZZ Ceti pulsators from these surveys, and several photometrically constant DA white dwarfs, which we then use to refine the location of the ZZ Ceti instability strip. [less ▲]

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See detail[18F]UCB-H as a new PET radiotracer for Synaptic vesicle protein 2A: A first clinical trial.
Bahri, Mohamed Ali ULiege; Stifkens, M; Bastin, Christine ULiege et al

in Tijdschrift voor Nucleaire Geneeskunde (2015, May 09), 37(3), 1457-1458

The synaptic vesicle protein 2A (SV2A) is widely distributed in the brain and has been demonstrated to be involved in vesicle trafficking. The critical role of SV2A in proper nervous system function is ... [more ▼]

The synaptic vesicle protein 2A (SV2A) is widely distributed in the brain and has been demonstrated to be involved in vesicle trafficking. The critical role of SV2A in proper nervous system function is shown, e.g., by the fact that it is a binding site and the primary mechanism of the antiepileptic drug levetiracetam. This drug has recently been suggested to reduce synaptic deficits in a mouse model for Alzheimer’s disease. We here aimed to investigate the cerebral distribution of [18F]UCB-H, which has a high affinity with the SV2A. Dynamic PET data of the head of 4 healthy volunteers were acquired over 100 minutes after injection of 170.4 ± 24.9 MBq of GMP produced [18F]UCB-H. The arterial input function (IF) was obtained by blood sampling but also derived from the dynamic data using the correlation coefficient method. Blood data revealed a consistent amount of [18F]UCB-H in whole blood and plasma indicating a very low degree of binding of the tracer to the red blood cells. The unchanged fraction of [18F]UCB-H in plasma showed a bi-exponential behavioral decrease with a starting fraction of 92% of the injected amount of the tracer, measured at 3 min post injection. This fraction decreased to about 50% at 10 min post injection. The image-derived arterial IFs showed to be very similar to the measured ones with a peak-ratio around 0.91 and an area-under-curve ratio about 0.98. The PET images showed a high and rapid uptake of [18F]UCB-H in the grey matter structures, matching the known ubiquitous distribution of the SV2A in the brain. The kinetics of the tracer in the brain was characterized by an initial high uptake phase followed by rapid washout. For the three standard compartmental models (1-tissue, 2-tissue, and Logan Plot), similar results were obtained with both the measured and image-derived IFs. Nevertheless the two-tissue compartment model fitted the experimental data best and provided a total distribution volume of the [18F]UCB-H in the brain greater than 7 mL/cm3 and a specific distribution volume around 3 mL/cm3. Our results suggest that [18F]UCB-H is a good candidate as radiotracer for brain SV2A proteins and could be used for human studies (dosimetry has already been reported elsewhere). Image-derived IF showed to be useful for quantitative studies without the need to the arterial blood sampling. This new tracer could help to assess SV2A modifications in neurological pathologies such as Alzheimer’s disease. [less ▲]

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See detailSujet de disputes ou objet de partage ? L’anthropologue au centre de conflits entre enfants de 5 à 8 ans (Liège, Belgique)
Campigotto, Marie ULiege

in AnthropoChildren : Perspectives ethnographiques sur les enfants & l'enfance = Ethnographic Perspectives in Children & Childhood (2015, May 08)

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See detailOne-year Prevalence of Migraine Using a Validated Extended French Version of the ID MigraineTM: a Belgian Population-Based Study
Schoenen, Jean ULiege; Streel, Sylvie ULiege; Donneau, Anne-Françoise ULiege et al

in Cephalalgia : An International Journal of Headache (2015, May), 35(6), 155-156

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See detailHigh output [18F]FDOPA on AllInOne (Trasis) at commercial scale
Otabashi, Muhammad; Cascione, Christian; Lemaire, Christian ULiege et al

in Journal of Labelled Compounds & Radiopharmaceuticals (2015, May), 58

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See detailThird-party mesenchymal stem cell infusion in kidney transplant recipient: 6-month safety interim analysis
WEEKERS, Laurent ULiege; ERPICUM, Pauline ULiege; DETRY, Olivier ULiege et al

in American Journal of Transplantation (2015, May), 15(suppl 3),

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See detailA phase 1b study of Trebananib plus Paclitaxel and Trastuzumab or Capecitabine and Lapatinib in patients with HER2+ locally recurrent or metastatic breast cancer
Kaufman, P.A.; Freyer, G.; Kemeny, M. et al

in Cancer Research (2015, May), 75(9), 5-19-14

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See detailNew Continuous Control Methodology for Nonlinear Dynamical Systems with Uncertain Parameters
Cho, Hancheol ULiege; Wanichanon, Thanapat; Udwadia, Firdaus

in International Conference on Uncertainty Quantification in Computational Sciences and Engineering (2015, May)

This paper presents a new reference-tracking control methodology for nonlinear dynamical systems in the presence of unknown, but bounded, uncertainties in the system. To this end, two controllers are ... [more ▼]

This paper presents a new reference-tracking control methodology for nonlinear dynamical systems in the presence of unknown, but bounded, uncertainties in the system. To this end, two controllers are combined. A nonlinear controller is first developed to exactly track the desired reference trajectory assuming no uncertainties in the nonlinear nominal system. The entire nonlinear dynamics of the nominal system is included and no approximations / linearizations are made. Next, an additional continuous controller is developed in closed form to compensate for uncertainties in the physical model by generalizing the concept of sliding surfaces. Unlike conventional sliding mode control, this Lyapunov-based approach eliminates the chattering problem by replacing a signum function with a set of continuous functions that may have different forms depending on practical considerations related to actuator implementation. Among these possible forms, special attention is paid to a controller with a PID form. By using Lyapunov stability theory it is shown that this additional controller forces the tracking errors that arise because of the uncertainties in the system to move into a small, user-specified region around the generalized sliding surface. Once these tracking errors enter this small region, if the original nonlinear system is assumed to be linearizable, then linear control theory will ensure that they will further converge to even smaller values. A numerical example is provided, in which a satellite in the presence of air drag is required to maintain a specific, circular orbit around the Earth whose gravity field is imprecisely known. The example demonstrates the accuracy, efficiency, and ease of implementation of the control methodology. [less ▲]

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See detailUPLC®-MS/MS, an analytical tool for the accurate and rapid quantification of phytoestrogen metabolites in milk
Daems, Frédéric ULiege; Jasselette, Christophe; Romnee, Jean-Michel et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2015, April 17), 19(2), 121-122

The term ‘phytoestrogen’ is used to define a wide variety of nonsteroidal compounds that occur naturally in many plants. When they are absorbed by cows, these polyphenolic compounds undergo ... [more ▼]

The term ‘phytoestrogen’ is used to define a wide variety of nonsteroidal compounds that occur naturally in many plants. When they are absorbed by cows, these polyphenolic compounds undergo biotransformation by specific bacteria present in the gastrointestinal tract. The resulting metabolites are absorbed in the organism and some are excreted in milk. The impact of these compounds on human health divides opinion. Some scientists believe that they might have adverse health effects. Others believe the opposite, especially with regard to their microbial metabolites, such as equol. Whatever one's view on the subject, scientists need accurate, sensitive and rapid analytical methods in order to continue the research on clarifying the phytoestrogen issue. Cow's milk is an animal product that is common in the human diet, and it is therefore important to evaluate its content of phytoestrogen metabolites. In order to study the human intake of equol via commercial milk, an analytical method was developed and validated following EMA/CVMP/VICH/463202/2009 guidelines. Enzymatic hydrolysis was used to release the equol. It was then extracted using double liquid/liquid extraction and analyzed using UPLC®-MS/MS, with an analysis runtime of only 5 min. This analytical method produced a linear calibration curve with a high correlation coefficient (R2≥0.996) between 5 and 1,000 ng mL−1. Good intra- and inter-day precision (RSDs≤5.3% and ≤5.2%, respectively) and accuracy (bias≤8.6%) were achieved. The recovery rate differed slightly among the different types of milk, ranging between 60.6±1.09% and 82.3±5.21%. Good method repeatability was observed (RSDs<15%). There was neither a matrix effect nor a carry-over effect, and the sample extracts were stable during storage for at least 7 days at −21°C and 5°C. In order to apply the proposed method and obtain an initial estimate of equol concentration in cow’s milk in Belgium, 44 samples of various brands found in several supermarkets and 5 raw milk samples from Walloon farms were analyzed. Equol was found in all the samples analyzed, with a concentration ranging from 10 to 50 ng mL−1 for conventional milk and from 70 to 130 ng mL−1 for organic milk. These results were compared with other European studies and the same trend was observed. The results obtained show the specificity, sensitivity and precision of this method for analyzing oestrogenic metabolite-equol in cow’s milk. This study should be extended to include a greater number of samples and be implemented over a longer period to see if there is a correlation between livestock practice and/or sample origins with the equol content in milk. The addition of other phytoestrogen compounds with this method, using UPLC®-MS/MS technology, could also lead to more reliable monitoring of these compounds in dairy production. [less ▲]

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See detailGenetic correlations between methane production and milk fatty acid contents of Walloon Holstein cattle throughout the lactation
Vanrobays, Marie-Laure ULiege; Vandenplas, Jérémie; Bastin, Catherine ULiege et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment (2015, April 16), 19(2), 117

Methane (CH4) from ruminal fermentation is the major greenhouse gas produced by dairy cattle, which contributes largely to climate change. Production of CH4 also represents losses of gross energy intake ... [more ▼]

Methane (CH4) from ruminal fermentation is the major greenhouse gas produced by dairy cattle, which contributes largely to climate change. Production of CH4 also represents losses of gross energy intake. Therefore, there is a growing interest in mitigating these emissions. Acetate and butyrate have common bio-chemical pathways with CH4. Because some milk fatty acids (FA) arise from acetate and butyrate, milk FA are often considered as potential predictors of CH4. However, relationships between these traits remain unclear. Moreover, the evolution of the phenotypic and genetic correlations of CH4 and milk FA across days in milk (DIM) has not been evaluated. The main goal of this study was to estimate genetic correlations between CH4 and milk FA contents throughout the lactation. Calibration equations predicting daily CH4 production (g.d-1) and milk FA contents (g.100 dl-1 of milk) from milk mid-infrared (MIR) spectra were applied on MIR spectra related to Walloon milk recording. Data included 243,260 test-day records (between 5 and 365 DIM) from 33,850 first-parity Holstein cows collected in 630 herds. Pedigree included 109,975 animals. Bivariate (i.e., CH4 production and one of the FA traits) random regression test-day models were used to estimate genetic parameters of CH4 production and seven groups of FA contents in milk. Saturated (SFA), short-chain (SCFA), and medium-chain FA (MCFA) showed positive averaged daily genetic correlations with CH4 production (from 0.25 to 0.29). Throughout the lactation, genetic correlations between SCFA and CH4 were low in the beginning of the lactation (0.11 at 5 DIM) and higher at the end of the lactation (0.54 at 365 DIM). Regarding SFA and MCFA, genetic correlations between these groups of FA and CH4 were more stable during the lactation with a slight increase (from 0.23 to 0.31 for SFA and from 0.23 to 0.29 for MCFA, at 5 and 365 DIM respectively). Furthermore, averaged daily genetic correlations between CH4 production and monounsaturated (MUFA), polyunsaturated (PUFA), unsaturated (UFA), and long-chain FA (LCFA) were low (from 0.00 to 0.15). However, these genetic correlations varied across DIM. Genetic correlations between CH4 and MUFA, PUFA, UFA, and LCFA were negative in early lactation (from -0.24 to -0.34 at 5 DIM) and increased afterward to become positive from 15 weeks till the end of the lactation (from 0.14 to 0.25 at 365 DIM). Finally, these results indicate that genetic and, therefore, phenotypic correlations between CH4 production and milk FA vary following lactation stage of the cow, a fact still often ignored when trying to predict CH4 production from FA composition. [less ▲]

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See detailHalogenated source gases measured by FTIR at the Jungfraujoch station: updated trends and new target species
Mahieu, Emmanuel ULiege; Bader, Whitney ULiege; Bovy, Benoît ULiege et al

in Geophysical Research Abstracts (2015, April 13), 17

In this contribution, we present decadal time series of halogenated source gases monitored at the high altitude station of the Jungfraujoch (46.5°N, 8°E, 3580 m asl) with Fourier Transform Infared (FTIR ... [more ▼]

In this contribution, we present decadal time series of halogenated source gases monitored at the high altitude station of the Jungfraujoch (46.5°N, 8°E, 3580 m asl) with Fourier Transform Infared (FTIR) spectrometers, within the framework of the Network for the Detection of Atmospheric Composition Change. Total column trends presented in previous studies for CFC-11, -12 and HCFC-22, CCl4, HCFC-142b, CF4 and SF6 will be updated using the latest available Jungfraujoch solar observations. Investigations dealing with the definition of approaches to retrieve additional halogenated source gases from FTIR spectra will also be evoked. Our trend results will be critically discussed and compared with measurements performed in the northern hemisphere by the in situ networks. [less ▲]

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See detailRetrieval of ammonia from ground-based FTIR measurements and its use for validation of satellite observations by IASI
Dammers, E; Palm, M; Warneke, T et al

in Geophysical Research Abstracts (2015, April 13), 17

Atmospheric Ammonia (NH3) has a major impact on human health and ecosystem services and plays a major role in the formation of aerosols [Erisman et al.,2013; Paulot and Jacob 2014]. NH3 concentrations are ... [more ▼]

Atmospheric Ammonia (NH3) has a major impact on human health and ecosystem services and plays a major role in the formation of aerosols [Erisman et al.,2013; Paulot and Jacob 2014]. NH3 concentrations are highly variable in space and time with overall short lifetime due to deposition and aerosol formation. The global atmospheric budget of nitrogen and in turn NH3 is still uncertain which asks for more ground-based and satellite observations around the world. Recent papers have described the possibility to measure NH3 with satellite infrared sounders which open up the way for calculations of global and regional nitrogen budgets [Clarisse et al 2009,Van Damme et al 2014a]. Validation of the satellite observations is essential to determine the uncertainty in the signal and its potential use. So far available surface layer observations of atmospheric NH3 concentrations have been used for comparisons with total columns retrieved from satellite observations [Van Damme 2014b]. We developed a retrieval for NH3 column density concentrations (molecules NH3/cm2) by fitting a set of spectral windows to ground-based solar absorption Fourier transform infrared (FTIR) measurements with the spectral fitting program SFIT4 [Hase et al., 2004]. The retrieval is then applied to FTIR measurements from a set of spectrometer sites from the Network for detection of Atmospheric Composition Change (NDACC) to retrieve NH3 columns for the sites located in Bremen, Germany; Lauder, New Zealand; Jungfraujoch, Switzerland; and the island of Reunion, France. Using eight years (2005-2013) of retrieved NH3 columns clear seasonal cycles are observed for each of the stations. Maximum concentrations can be related to NH3 emission sources, specific for the regions. A comparison between the retrieved NH3 columns and observations from the recent IASI- NH3 product [Van Damme et al, 2014a] using strict spatial and temporal criteria for the selection of observations showed a good correlation (R=0.82; slope=0.63). The IASI- NH3 columns for the Bremen and Lauder area show similar temporal cycles when compared to the FTIR observations. [less ▲]

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See detailIndividual variation of gait characteristics along a 500 meter walk in people with multiple sclerosis and healthy volunteers
Phan-Ba, Rémy; Pierard, Sébastien ULiege; Giet, Amaury et al

in Multiple Sclerosis Journal (2015, April 10), 21(4), 532-533

Background: we previously demonstrated the usefulness of the Deceleration Index (DI, the ratio between the last 100m of the Timed 500-Meter Walk test –T500MW – and the walking speed - WS – of the Timed 25 ... [more ▼]

Background: we previously demonstrated the usefulness of the Deceleration Index (DI, the ratio between the last 100m of the Timed 500-Meter Walk test –T500MW – and the walking speed - WS – of the Timed 25-Foot Walk Test with a propelled start – T25FW+) to evaluate motor fatigue over a long walking distance in people with multiple sclerosis (pwMS). We also recently designed and internally validated a new gait analysis tool for pwMS (GAIMS) that can measure other relevant gait characteristics than the sole WS, such as ataxia, asymmetry and perhaps spasticity. Aims: (i) To compare various gait characteristics between the last and the first 100m of the T500MW in a population of pwMS and healthy volunteers (HV), (ii) to compare the ratio between the last and the first 100m of the T500MW with the DI, and (iii) their relationship with the EDSS. Methods : Subjects were asked to perform the T25FW+ and the T500MW as part of a multimodal evaluation at the MS Clinic of the CHU of Liège. Their gait characteristics were measured using GAIMS. (i) Paired Student’s t-tests were performed on various gait characteristics extracted during the last and first 100m of the T500MW with .05 as a level of significance, (ii) Spearman correlation coefficient (ρ) was calculated (ii) between these ratio and (iii) subject’s EDSS. Results: Seventy-one pwMS and 129 were enrolled in our study. (i) Significant differences were observed for speed related gait characteristics between the last and first 100m of the T500MW, but also for gait characteristics related to ataxia and precision of foot placement. (ii) A moderate positive correlation was observed between the WS ratio of the last and first 100m of the T500MW and the DI. (iii) The correlation between the DI and the EDSS was weakly negative, while the one between the last and first 100m of the T500MW ratio and the EDSS was moderatly negative. Conclusion: (i) As previously demonstrated, we here confirm that alongside to WS, there are other gait features affected by locomotor fatigue over a long walking distance, (ii) the moderate positive correlation between the DI and the last/first 100m of the T500MW indicates that these measures are not the same and that next to a long distance walking test such as the T500MW, a short one such as the T25FW+ remains useful. (iii) The last/first 100m of the T500MW is better correlated to the EDSS and might be a better predictive tool of pwMS’ neurologic state than the DI. [less ▲]

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See detailBaseline Fibulin3 concentrations are associated with incidence of clinical knee OA after 30 months in overweight and obese women
Runhaar, Jos; Sanchez, Christelle ULiege; Henrotin, Yves ULiege et al

in Osteoarthritis and Cartilage (2015, April), 23(S2), 83

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See detailBiogenic Volatile Organic Compound (BVOC) emissions from agricultural crop species: is guttation a possible source for methanol emissions following light/dark transition?
Mozaffar, Ahsan ULiege; Amelynck, Crist; Bachy, Aurélie ULiege et al

in Geophysical Research Abstracts (2015, April), 17(EGU2015-2110-1),

In the framework of the CROSTVOC (CROp STress VOC) project, the exchange of biogenic volatile organic compounds (BVOCs) between two important agricultural crop species, maize and winter wheat, and the ... [more ▼]

In the framework of the CROSTVOC (CROp STress VOC) project, the exchange of biogenic volatile organic compounds (BVOCs) between two important agricultural crop species, maize and winter wheat, and the atmosphere has recently been measured during an entire growing season by using the eddy covariance technique. Because of the co-variation of BVOC emission drivers in field conditions, laboratory studies were initiated in an environmental chamber in order to disentangle the responses of the emissions to variations of the individual environmental parameters (such as PPFD and temperature) and to diverse abiotic stress factors. Young plants were enclosed in transparent all-Teflon dynamic enclosures (cuvettes) through which BVOC-free and RH-controlled air was sent. BVOC enriched air was subsequently sampled from the plant cuvettes and an empty cuvette (background) and analyzed for BVOCs in a high sensitivity Proton-Transfer Reaction Mass Spectrometer (hs-PTR-MS) and for CO2 in a LI-7000 non-dispersive IR gas analyzer. Emissions were monitored at constant temperature (25 °C) and at a stepwise varying PPFD pattern (0-650 µmol m-2 s-1). For maize plants, sudden light/dark transitions at the end of the photoperiod were accompanied by prompt and considerable increases in methanol (m/z 33) and water vapor (m/z 39) emissions. Moreover, guttation droplets appeared on the sides and the tips of the leaves within a few minutes after light/dark transition. Therefore the assumption has been raised that methanol is also coming out with guttation fluid from the leaves. Consequently, guttation fluid was collected from young maize and wheat plants, injected in an empty enclosure and sampled by PTR-MS. Methanol and a large number of other compounds were observed from guttation fluid. Recent studies have shown that guttation from agricultural crops frequently occurs in field conditions. Further research is required to find out the source strength of methanol emissions by this guttation phenomenon in real environmental conditions. [less ▲]

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See detailImproving energy partitioning and the nighttime energy balance by implementation of a multi-layer energy budget in ORCHIDEE-CAN
Chen, Yiying; Ryder, James; Naudts, Kim et al

in Geophysical Research Abstracts (2015, April), 17

Canopy structure is one of the most important vegetation characteristics for land-atmosphere interactions as it determines the energy and scalar exchanges between land surface and overlay air mass. In ... [more ▼]

Canopy structure is one of the most important vegetation characteristics for land-atmosphere interactions as it determines the energy and scalar exchanges between land surface and overlay air mass. In this study we evaluated the performance of a newly developed multi-layer energy budget (Ryder et al., 2014) in a land surface model, ORCHIDEE-CAN (Naudts et al., 2014), which simulates canopy structure and can be coupled to an atmospheric model using an implicit procedure. Furthermore, a vertical discrete drag parametrization scheme was also incorporated into this model, in order to obtain a better description of the sub-canopy wind profile simulation. Site level datasets, including the top-of-the-canopy and sub-canopy observations made available from eight flux observation sites, were collected in order to conduct this evaluation. The geo-location of the collected observation sites crossed climate zones from temperate to boreal and the vegetation types included deciduous, evergreen broad leaved and evergreen needle leaved forest with maximum LAI ranging from 2.1 to 7.0. First, we used long-term top-of-the-canopy measurements to analyze the performance of the current one-layer energy budget in ORCHIDEE-CAN. Three major processes were identified for improvement through the implementation of a multi-layer energy budget: 1) night time radiation balance, 2) energy partitioning during winter and 3) prediction of the ground heat flux. Short-term sub-canopy observations were used to calibrate the parameters in sub-canopy radiation, turbulence and resistances modules with an automatic tuning process following the maximum gradient of the user-defined objective function. The multi-layer model is able to capture the dynamic of sub-canopy turbulence, temperature and energy fluxes with imposed LAI profile and optimized parameter set at a site level calibration. The simulation result shows the improvement both on the nighttime energy balance and energy partitioning during winter and presents a better Taylor skill score, compared to the result from single layer simulation. The importance of using the multi-layer energy budget in a land surface model for coupling to the atmospheric model will also be discussed in this presentation. [less ▲]

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See detailThe CROSTVOC project – an integrated approach to study the effect of stress on BVOC exchange between agricultural crops and grassland ecosystems and the atmosphere
Amelynck, Crist; Heinesch, Bernard ULiege; Aubinet, Marc ULiege et al

in Geophysical Research Abstracts (2015, April), 17

Global changes in atmospheric composition and climate are expected to affect BVOC exchange between terrestrial vegetation and the atmosphere through changes in the drivers of constitutive BVOC emissions ... [more ▼]

Global changes in atmospheric composition and climate are expected to affect BVOC exchange between terrestrial vegetation and the atmosphere through changes in the drivers of constitutive BVOC emissions and by increases in frequency and intensity of biotic or abiotic stress episodes. Indeed, several studies indicate changes in the emission patterns of constitutive BVOCs and emission of stress-induced BVOCs following heat, drought and oxidative stress, amongst others. Relating changes in BVOC emissions to the occurrence of one or multiple stressors in natural environmental conditions is not straightforward and only few field studies have dealt with it, especially for agricultural crop and grassland ecosystems. The CROSTVOC project aims to contribute in filling this knowledge gap in three ways. Firstly, it aims at performing long-term BVOC emission field measurements from maize (Zea mays L.) and wheat (Triticum aestivum L.), two important crop species on the global scale, and from grassland. This should lead to a better characterization of (mainly oxygenated) BVOC emissions from these understudied ecosystems, allowing a better representation of those emissions in air quality and atmospheric chemistry and transport models. BVOC fluxes are obtained by the Disjunct Eddy Covariance by mass scanning (DEC-MS) technique, using a hs-PTR-MS instrument for BVOC analysis. Secondly, the eddy covariance BVOC flux measurements (especially at the grassland site) will be accompanied by ozone flux, chlorophyll fluorescence, photosynthesis and soil moisture measurements, amongst others, to allow linking alterations in BVOC emissions to stress episodes. Simultaneously, automated dynamic enclosures will be deployed in order to detect specific abiotic and biotic stress markers by PTR-MS and identify them unambiguously by GC-MS. Thirdly, the field measurements will be accompanied by laboratory BVOC flux measurements in an environmental chamber in order to better disentangle the responses of the BVOC emissions to driving factors that co-occur in field conditions and to determine the influence of single abiotic stressors on BVOC emissions. Next to a general presentation, some preliminary results of the project will be shown. [less ▲]

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See detailWolff’s Law and the Interplay between Bone Structure and External Loading
Ruffoni, Davide ULiege; Christen, Patrik; Scherf, Heike et al

in IBMS BoneKEy (2015, April), 13

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See detailFacteurs génétiques et risque de dysglycémie dans des familles de diabétiques de type 2: l’étude DESCENDANCE
Franc, S; Cauchi, S; Yengo, L et al

in Diabètes & Métabolism (2015, April), 41(s1), 10-35

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See detailAssessment of damage and anisotropic plasticity models to predict Ti-6Al-4V behavior
Guzmán Inostroza, Carlos Felipe ULiege; Tuninetti, Víctor; Gilles, Gaëtan ULiege et al

in Key Engineering Materials [=KEM] (2015, April), 651-653

The plastic behavior of the Ti-6Al-4V alloy includes several features as strength differential effect, anisotropy and yield strength sensitivity to temperature and strain rate. Monotonic tensions in the ... [more ▼]

The plastic behavior of the Ti-6Al-4V alloy includes several features as strength differential effect, anisotropy and yield strength sensitivity to temperature and strain rate. Monotonic tensions in the three orthogonal directions of the material are performed to identify the Hill ’48 yield criterion. Monotonic compression and plane strain tensile tests are also included in the experimental campaign to identify the orthotropic yield criterion of CPB06. An assessment of the two models is done by comparing the yield loci and the experimental data points for different levels of plastic work. A first approach of the damage modelling of the Ti-6AL-4V alloy is investigated with an extended Gurson-Tvergaard-Needleman damage model based on Hill ’48 yield criterion. Finite element simulations of the experiments are performed and numerical results allows checking force-displacement curves until rupture and local information like displacement and strain fields. The prediction ability of the Hill ’48, CPB and extended Gurson models are assessed on simple shear and notched tensile tests until fracture. [less ▲]

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See detailGAIMS: a tool specifically developed for the clinical gait analysis of patients with multiple sclerosis
Pierard, Sébastien ULiege; Phan-Ba, Rémy; Giet, Amaury et al

in Multiple Sclerosis Journal (2015, April), 21(4), 498-499

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See detailDiurnal and seasonal variability of CO2 fluxes over a degraded Woodland under a Sudanian climate in Northern Benin (West Africa)
Ago, Expédit Evariste ULiege; Serça, Dominique; Agbossou, Euloge Kossi et al

in Geophysical Research Abstracts (2015, April), 17

Turbulent CO2 exchanges over a degraded woodland were measured during 17 months (from November 2005 to March 2007) by an eddy-covariance system at Nangatchori in the northern part of Benin, West Africa ... [more ▼]

Turbulent CO2 exchanges over a degraded woodland were measured during 17 months (from November 2005 to March 2007) by an eddy-covariance system at Nangatchori in the northern part of Benin, West Africa. The site (Lat 9.65°N, Long 1.74°E, Alt: 432 m), under a Sudanian climate, is one of the sites that were equipped in the framework of the international AMMA-CATH program. The site was highly disturbed during preceding years by illegal tree logging, agricultural activities, cattle pasture, and bushfire. The footprint area is mainly formed by herbs and crops with some sparse shrubs and trees. Fluxes data were completed during the same period by meteorological measurements made at the Nalohou site located approximately 20 km from Nangatchori, and by an inventory of dominating species on 1km2 area around the tower during the wet season. Fluxes response to climatic variables was analyzed. The annual drought and moisture cycle was found to be the main controlling factor of the ecosystem dynamics. A very clear response of CO2 fluxes to PPFD appears, but is different according to seasons. During wet season, CO2 uptake increases with increasing PPFD following a typical curvilinear function and saturates for high PPFD (PPFD > 1000 µmol m-2 s-1), while during dry season, a very weak linear response of CO2 fluxes was observed. No clear dependency of the total ecosystem respiration on temperature was observed. At an annual scale (from November 1st 2005 to October 31st 2006), net carbon sequestered by the ecosystem was 18 +- 5 g C m-2. Finally, with respect to the water use the ecosystem appeared to be more efficient during morning and wet season than during afternoon and dry period. [less ▲]

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See detailMeasuring and modelling the intra-day variability of the CO2 & CO2 vertical soil profile production in a Scots pine forest
Longdoz, Bernard ULiege; Goffin, Stéphanie; Parent, Florian et al

in Geophysical Research Abstracts (2015, April), 17

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See detailConjonctivite néonatale à Neisseria Gonorrhoeae: pas seulement du passé
Tribolet, Sophie; Lefevre, Annabelle; Gillard, Perrine et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March 13), 17(1), 113

L’ophtalmie néonatale n’appartient pas qu’au passé, l’incidence d’infections à Neisseria Gonorrhaea étant en augmentation en Belgique. Différentes prophylaxies sont proposées (nitrate d’argent, povidone ... [more ▼]

L’ophtalmie néonatale n’appartient pas qu’au passé, l’incidence d’infections à Neisseria Gonorrhaea étant en augmentation en Belgique. Différentes prophylaxies sont proposées (nitrate d’argent, povidone iodine, tétracycline, érythromycine, acide fusidique), avec leurs avantages et inconvénients respectifs. Aucun consensus clair n’est établi quant à la solution la plus efficace, certains remettant en doute leur utilisation dans les pays développés. [less ▲]

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See detailImplementation of placental transfusion protocol
Lefebvre, Caroline; MASSON, Véronique ULiege; Kalenga, Masendu ULiege et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March 12), 17(1), 72

A clear protocol for placental transfusion gives the opportunity to improve care of preterm infants. Initial information session and simulation practice for medical and midwifes staffs helps with its ... [more ▼]

A clear protocol for placental transfusion gives the opportunity to improve care of preterm infants. Initial information session and simulation practice for medical and midwifes staffs helps with its implementation. Delayed clamping and cord milking are not difficult after a learning phase like for most new procedures. [less ▲]

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See detailL'histiocytose de Langerhans, une cause rare de Blueberry Muffin Syndrome
Kreins, Nathalie; Kalenga, Masendu ULiege; RIGO, Vincent ULiege

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March 12), 17(1), 72

La présentation du Blueberry Muffin Syndrome est typique, et permet de rapidement orienter le bilan étiologique. La biopsie cutanée est importante pour établir le diagnostic, qui lui-même conditionne le ... [more ▼]

La présentation du Blueberry Muffin Syndrome est typique, et permet de rapidement orienter le bilan étiologique. La biopsie cutanée est importante pour établir le diagnostic, qui lui-même conditionne le pronostic. [less ▲]

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See detailUltra-low power microsystems integrated
Laurent, Philippe ULiege; Dupont, François ULiege; Stoukatch, Serguei ULiege et al

in Conference proceedings (2015, March 11)

Microsys has developed wireless microsystems using off-the-shelf components comprising ultra-low power sensors such as temperature, humidity and luminosity. We will show how to make the microsystem more ... [more ▼]

Microsys has developed wireless microsystems using off-the-shelf components comprising ultra-low power sensors such as temperature, humidity and luminosity. We will show how to make the microsystem more compact by decreasing the power consumption. So doing, no or little maintenance is required, leading to an efficient Wireless Sensor Network (WSN). [less ▲]

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See detailBenefits of placental transfusion in very preterm infants
Lefebvre, Caroline; MASSON, Véronique ULiege; Kalenga, Masendu ULiege et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March), 17(1), 84

Introduction Cord clamping is not a trivial process. Its timing influences the significant physiological changes involved with this nearly universal practice. While the fetal and placental blood volumes ... [more ▼]

Introduction Cord clamping is not a trivial process. Its timing influences the significant physiological changes involved with this nearly universal practice. While the fetal and placental blood volumes add up to 100-120 ml/kg, their distributions differ between preterm and term neonates. The placenta accounts for 50% of the total blood volume in preterm infants and for only 33% in term neonates. Placental transfusion for 60 seconds increases neonatal blood volume by ± 16 ml/kg. In randomized trials, delayed cord clamping in preterm birth is associated with a more stable transitional circulation, a decrease need for inotropic support, and reduce blood transfusions, necrotizing enterocolitis, and intraventricular hemorrhages. Given those benefits, placental transfusion is integrated systematically in our management of preterm births since October 2013. This study aims to confirm expected benefits in a clinical setting. Patients and Methods We conducted a retro-prospective trial in a single tertiary care center. Very preterm infants (VPTi; <32 weeks GA) and VLBWi (BW<1500g) born between April 1st and September 30th 2013 were managed conventionally, with early cord clamping and constitute the control group. These data were collected retrospectively. October 2013 is the month for the new protocols implementation, and infants born this month are not included. Data from VPTi and VLBWi with delayed cord clamping or cord milking were collected prospectively from November 1st 2013 to April 30st 2014. Exclusion criteria were maternal and fetal vital emergencies, Rhesus sensitization, known major congenital abnormalities, tight nuchal cord, meconium teinted liquor, or mother infection by HIV or hepatitis. Results Fifty-two patients are included in the control group. In the second period, 26/XX preterm infants received a placental transfusion, including 6 with a 60 seconds delay in cord clamping and 20 with cord milking. Maternal and neonates’ characteristics were not significantly different. Mean birth weights (BW) were 1208g in the control and 1157g in the placental transfusion groups, with mean gestational age of 28 weeks 4/7 and 28 weeks 6/7, respectively. Mean arterial pressure is significantly increased with placental transfusion (H0 p=0.0006), (H12 p=0.032), (H24 p=0.01). Hemoglobin (H24 p=0,01) and hematocrit (H0 p=0,03), (H12 p=0,05), (H24 p=0,007) are also significantly higher. The number of transfusions per patient transfused (early group 3±2.5 vs. placental transfusion 1±0.4) is significantly lower (p=0.038). No infant with a BW>950g managed with delayed clamping or cord milking did required a transfusion. Conclusion Placental transfusion is associated with a higher blood pressure during the first 24 hours. Placental transfusion also reduces transfusion requirements, with reduction in the number of multi-transfused patients. We found this procedure safe and did not identify short or medium term adverse effects. For preterm infants, the third stage of labor management should evolve toward a more physiological practice, with systematic placental transfusion. [less ▲]

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See detailDesign and implementation of a ‘physical activity day’ for overweight and obese youth
Cloes, Marc ULiege; DEWANDRE, Anne-Cécile ULiege; LEBRETHON, Marie-Christine ULiege et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March), 17(1),

This study aimed to analyze the development and implementation of an adapted physical activity day expected to underline to overweight/obese youth the role of PA and hw they could be more active in their ... [more ▼]

This study aimed to analyze the development and implementation of an adapted physical activity day expected to underline to overweight/obese youth the role of PA and hw they could be more active in their daily life. [less ▲]

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See detailRole of adamalysin proteases in modulations of tumor microenvironment and premetastatic niches
Donati, Kim ULiege; Bekaert, Sandrine; Sepult, Christelle ULiege et al

in Revue des Maladies Respiratoires (2015, March), 32

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See detailMulticenter Belgian experience of sofosbuvir (medical need program) in very difficult-to-treat HCV patients: safety and efficacy results.
Degre, D; Laleman, W; Verhelst, X et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 03

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See detailImpact of intensive enteral nutrition in association with corticosteroïds in the treatment of severe alcoholic hepatitis: a multicenter randomized controlled trial
Moreno, C; Trepo, E; Louvet, A et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 01

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See detailMetabolomic, proteomic and preclinical imaging of patient-derived tumor xenografts for improving treatment of liver metastases patients
Perez Palacios, A; Blomme, A; Boutry, S et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 134

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See detailMultitasking abilities in persons diagnosed with schizophrenia: a new tool and cognitive model.
Laloyaux, Julien ULiege; Van der Linden, Martial ULiege; Laroi, Frank ULiege

in Schizophrenia Bulletin (2015, March), 41(Supplement 1),

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia, and in particular during multitasking activities (Semkovska et al., 2010). Multitasking refers to ... [more ▼]

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia, and in particular during multitasking activities (Semkovska et al., 2010). Multitasking refers to activities (e.g. preparing a meal) where the person has to: (a) carry out and alternate between different tasks that vary in terms of priority, difficulty and duration; (b) define the tasks’ targets; (c) and where the person is faced with unexpected problems during the realization of these tasks (Burgess, 2000). However, the cognitive underpinnings of multitasking abilities have never been adequately explored in schizophrenia. Further, only two cognitive models exist in the literature, which are based on student (Logie et al., 2011) and neurological (Burgess et al., 2000) samples. Both of these models suggest three primary constructs: Memory, Planning and Intent. There are, however, several limitations related to the way multitasking abilities were evaluated in these studies. We thus developed a computerized real-life activity task - the Computerized Meeting Preparation Task (CPMT), which was specifically designed to take into account the multitasking nature of certain everyday life activities. Using this task, and based on previous studies (Burgess et al., 2000; Logie et al., 2011), the aim of the present study was to evaluate multitasking abilities in schizophrenia and to do so in a new cognitive model of multitasking that takes into account certain cognitive functions that are not integrated in existing models. Methods: Fifty-seven individuals with schizophrenia and 41 matched healthy controls completed the CMPT. Participants were also evaluated with a battery of cognitive tests. Results: The results suggest that the CMPT possesses good sensitivity and confirmed the three underlying constructs of multitasking (Memory, Planning and Intent), which were found to be underpinned by several cognitive functions and multitasking aspects. Conclusion: Taken together, this new cognitive model and the CMPT could be a good basis for cognitive interventions of multitasking abilities in schizophrenia. Burgess, P.W., 2000. Strategy application disorder: the role of the frontal lobes in human multitasking. Psychol Res 63, 279-288. Logie, R., et al., 2011. Multitasking: multiple, domain-specific cognitive functions in a virtual environment. Mem Cogn 39, 1561-1574. Semkovska, M. et al., 2004. Assessment of executive dysfunction during activities of daily living in schizophrenia. Schizophr Res 69, 289-300. [less ▲]

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See detailExpel: a novel non-destructive method for mining soluble tumor biomarkers
Costanza, B; Blomme, A; MUTIJIMA NZARAMBA, Eugène ULiege et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 13

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See detailEvaluation de l’efficacité de la simulation haute fidélité dans la prise en charge des troubles du rythme cardiaque chez l’enfant: étude pilote
SCHUMACHER, Katharina ULiege; Seghaye, Marie-Christine ULiege; Baugnon, Thomas et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, March), 17(1),

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See detailInfusion of third-party mesenchymal stream cells after liver transplantation: a phase-1, open-label, clinical study
DETRY, Olivier ULiege; VANDERMEULEN, Morgan ULiege; DELBOUILLE, Marie-Hélène ULiege et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 29

Background: Mesenchymal stromal cells (MSC) are multipotent bone marrow progenitors that have demonstrated significant immunosuppressive effects in various in vivo and in vitro studies. This study aimed ... [more ▼]

Background: Mesenchymal stromal cells (MSC) are multipotent bone marrow progenitors that have demonstrated significant immunosuppressive effects in various in vivo and in vitro studies. This study aimed to be the first evaluation of the safety and tolerability of MSC infusion after liver transplantation in a prospective, controlled phase-1 study. This study aimed to be the first evaluation of the safety and tolerability of MSC infusion after liver transplantation in a prospective, controlled phase-1 study. Patients & Methods: Clinical grade MSCs were locally collected from the bone marrow of unrelated healthy donors. They were cultured in a GMP-compliant lab, underwent extensive quality controls and were frozen for storage in a MSC bank. When needed for patient treatment, MSC were thawed and intravenously injected into patients. 10 liver transplant recipients under standard immunosuppression (TAC-MMF-low dose steroids until day 30) received 1.5-3x106/kg MSC on post-operative day 3±2. These patients were prospectively compared to a group of 10 control (MSC-) liver recipients. Primary endpoints were MSC infusion toxicity, and incidence of cancer and opportunistic infections at month 6. Secondary endpoints were patient and graft survivals and rejection at month 6, as well as the effects of MSC on recipients’ immune function and on immunohistology of at month 6 graft biopsies. Results: No MSC infusional toxicity was observed. Both groups were comparable in terms of donor and recipient characteristics. There was no difference in primary end-points between control and MSC groups. No patient developed de novo cancer. There was no statistical difference in patient and graft survivals or in rejection rates. There was no graft rejection in the MSC group. Month-6 graft biopsies were not different according to Banff and fibrosis scores. Discussion: This phase 1 study showed excellent tolerability and safety of a single infusion of third-party MSC after liver transplantation. There were no graft safety issues and no excess of immunosuppression after MSC injection. Further analyses of consequences of MSC injection on the immune profile are needed. The possibility of avoiding calcineurin-inhibitors with repeated MSC injections as main immunosuppressive therapy and/of tolerance induction by MSC infusion should be investigated by further studies. [less ▲]

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See detailAvancement du projet de l'inventaire typologique et dendrochronologique des charpentes anciennes en région Bruxelles-Capitale
Weitz, Armelle ULiege; Charruadas, Paulo ULiege; Crémer, Sarah et al

in Archaeologia Mediaevalis (2015, March), 38

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See detailExploring limiting factors in the prediction of allogeneic HSCT related mortality: an in-silico machine learning analysis of the acute leukemia working party (ALWP) registry of the EBMT
SHOUVAL, R.; LABOPIN, M.; UNGER, R. et al

in Bone Marrow Transplantation (2015, March), 50

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See detailPhysical rehabilitation in musculoskeletal conditions: which method?
Bruyère, Olivier ULiege

in Osteoporosis International (2015, March), 26(S1), 68

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See detailDairy products & Bone Health: Turning facts and beliefs into clinical practice
Bruyère, Olivier ULiege

in Osteoporosis International (2015, March), 26(S1), 383

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See detailAssessment and determinants of aesthetic discomfort in hand osteoarthritis: The Liège Hand Osteoarthritis Cohort (LICOH)
Neuprez, Audrey ULiege; Bruyère, Olivier ULiege; Dardenne, Nadia ULiege et al

in Osteoporosis International (2015, March), 26(S1), 43-44

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See detailAnalyse rétrospective des données concernant les patientes avec diabète gestationnel au CHU de Liège
RADERMECKER, Régis ULiege; PHILIPS, Jean-Christophe ULiege; Sepulchre, E

in Diabètes & Métabolism (2015, March), 41

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See detailRemboursement de la mesure continue du glucose en Belgique: un exemple de multidisciplinarité
RADERMECKER, Régis ULiege; Contessi, El

in Diabètes & Métabolism (2015, March), 41

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See detailMilan Kundera et "La fête de l'insignifiance".
Mus, Francis ULiege

in L'art du roman (2015, February 20)

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See detailLes PPP comme nouveau mode de régulation du marché de l'accompagnement des demandeurs d'emploi. A chaque modèle de partenariat son type de stratégie
Remy, Céline ULiege

in Cahiers Loyola (2015, February), 1

Cette communication vise à montrer en quoi les partenariats publics-privés (PPP) constituent désormais un nouveau mode de régulation du marché de l’accompagnement des demandeurs d’emploi. Les services ... [more ▼]

Cette communication vise à montrer en quoi les partenariats publics-privés (PPP) constituent désormais un nouveau mode de régulation du marché de l’accompagnement des demandeurs d’emploi. Les services publics de l’emploi (SPE) doivent établir des PPP avec des prestataires de service pour la mise en place de formation à destination des demandeurs d’emploi. La réalisation de trois études de cas au sein des SPE, dont deux en Belgique et une en Suisse, nous permet de mettre en évidence une forte influence du modèle de gestion du PPP sur la collaboration entre les parties-prenantes mais aussi sur les stratégies développées par les prestataires pour surmonter les problèmes liés à la collaboration avec l’Office de l’Emploi et à la mise en place de la prestation de service. [less ▲]

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See detailAzione, testualizzazione, notazione
Dondero, Maria Giulia ULiege

in Espressione e contenuto. Rivista on-line dell'AISS Associazione Italiana di Studi Semiotici (2015, February), 18/19

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See detailCastalia — A Mission to a Main Belt Comet
Jones, G. H.; Altwegg, K.; Bertini, I. et al

in LPI (2015, January 01), 1829

Main Belt Comets (MBCs) are a newly identified class of solar system object, having asteroid-like orbits but sometimes exhibiting comet-like behavior. We present the case for a mission to an MBC, to be ... [more ▼]

Main Belt Comets (MBCs) are a newly identified class of solar system object, having asteroid-like orbits but sometimes exhibiting comet-like behavior. We present the case for a mission to an MBC, to be submitted to the European Space Agency. [less ▲]

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See detailMassive stars: privileged sources of cosmic-rays for interstellar astrochemistry
De Becker, Michaël ULiege

in Bulletin de la Société Royale des Sciences de Liège (2015, January), 84

Massive stars can be considered as crucial engines for interstellar physics. They are indeed the main providers of UV radiation field, and constitute a substantial source of chemical enrichment. On their ... [more ▼]

Massive stars can be considered as crucial engines for interstellar physics. They are indeed the main providers of UV radiation field, and constitute a substantial source of chemical enrichment. On their evolution time-scale (at most about 10 Myr), they typically stay close to their formation site, i.e. close to molecular clouds very rich in interstellar molecules. These stellar objects have also the property to be involved in particle acceleration processes leading to the production of high energy charged particles (cosmic-rays). After rejection in the interstellar medium, these particles will play a substantial role in processes such as those simulated in various facilities dedicated to experimental astrochemistry. This short contribution intends to put these particles, crucial for astrochemistry, in their adequate astrophysical context. [less ▲]

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See detailFood provioning influences ranging patterns in northern pigtailed macaques (Macaca leonina)
Huynen, Marie-Claude ULiege; Savini, Tommaso ULiege; Asensio, Norberto et al

in International Journal of Primatology (2015, January)

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See detailExperimental astrochemistry: from ground-based to space-borne laboratories (Foreword)
De Becker, Michaël ULiege; Cottin, Hervé; Fleury-Frenette, Karl ULiege et al

in Bulletin de la Société Royale des Sciences de Liège (2015, January), 84(4-6),

The investigation of the origin and evolution of molecules in space environments, either in interstellar or interplanetary conditions, constitutes a topic of high importance in modern space sciences. The ... [more ▼]

The investigation of the origin and evolution of molecules in space environments, either in interstellar or interplanetary conditions, constitutes a topic of high importance in modern space sciences. The presence of diversified and complex molecules motivates astrochemists to explore their formation mechanisms along with the physical conditions ruling these physico-chemical processes. Beside theoretical approaches aiming at simulating these processes, experimental techniques are nowadays frequently applied. Both laboratory and space experiment projects allow to reproduce to some extent the adequate conditions to understand some of these processes. The most recent results based on these techniques, and the prospects for future investigations, including the use of space platforms, were the scientific motivation of this workshop. These proceedings summarize a part of the content of this workshop, including abundant references to the relevant bibliography. [less ▲]

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See detailExercice stress echocardiography in secondary mitral regurgitation : impact of pulmonary hypertension
MAGNE, Julien; PIERARD, Luc ULiege; LANCELLOTTI, Patrizio ULiege

in Archives of Cardiovascular Diseases (2015, January), 7

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See detailGene expression of growth factors and apoptosis regulating proteins in rat myocardium after exposure to endocrine disrupting chemicals : a preliminary study
ROUATBI, Hatem ULiege; GERARD, Arlette ULiege; Seghaye, Marie-Christine ULiege

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 99

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See detailAutoimmune thyroid diseases in early childhood three case reports
Guffins, Amandine ULiege; HARVENGT, Julie ULiege; LUYCKX, F. et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 41

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See detailUne gangrène digitale humide traitée de façon conservatrice
Janssen, Aurélie; STERGIOPOULOU, Theodouli ULiege; NYAMUGABO MUNYERE NKANA, Kindja ULiege et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 64

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See detailPromotion of physical activity among children and adolescents followed for overweight or obesity in
DEWANDRE, Anne-Cécile ULiege; HARVENGT, Julie ULiege; LAGASSE, Celine ULiege et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 40

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See detailComplications de l'appendicite aiguë chez l'enfant : à propos d'un cas
Janssen, Aurélie; NYAMUGABO MUNYERE NKANA, Kindja ULiege; STERGIOPOULOU, Theodouli ULiege et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 66

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See detailRespiratory distress or eating disorder could: it be a vascular ring ?
Solowianiuk, Marie ULiege; FARHAT, Nesrine ULiege; HOLZKI, Josef ULiege et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 98

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See detailPaucisymptomatic presentation of viral myocarditis in children
TSHIMANGA, Prisca ULiege; DARON, B.; FARHAT, Nesrine ULiege et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 98

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See detailDoes gestational diabetes influence foetal organ function ?
Guffins, Amandine ULiege; FARHAT, Nesrine ULiege; GKIOUGKI, Evangelia ULiege et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 99

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See detailJAWAC evolving technologies to study sleep disturbance in obese adolescents - a preliminary study
Barrea, Christophe ULiege; HARVENGT, Julie ULiege; LEBRETHON, Marie-Christine ULiege et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 107

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See detailSexually dimorphic effect of gestational exposure to BPA on DNA methylation in the rat placenta
Fudvoye, Julie ULiege; Dehan, Pierre ULiege; Trooskens, G. et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 37

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See detailCellulite faciale sévère au départ d'une lésion de varicelle - à propos d'un cas
Bourcy, Emilie ULiege; Saliba, Mariane ULiege; NYAMUGABO MUNYERE NKANA, Kindja ULiege et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 113

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See detailMono- and Biallelic deletion of neurexin - à propos of 3 cases
Barrea, Christophe ULiege; RAMAEKERS, Vincent ULiege; Seghaye, Marie-Christine ULiege

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015, January), 17(1), 107

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