References of "Scientific journals"      in Complete repository Arts & humanities   Archaeology   Art & art history   Classical & oriental studies   History   Languages & linguistics   Literature   Performing arts   Philosophy & ethics   Religion & theology   Multidisciplinary, general & others Business & economic sciences   Accounting & auditing   Production, distribution & supply chain management   Finance   General management & organizational theory   Human resources management   Management information systems   Marketing   Strategy & innovation   Quantitative methods in economics & management   General economics & history of economic thought   International economics   Macroeconomics & monetary economics   Microeconomics   Economic systems & public economics   Social economics   Special economic topics (health, labor, transportation…)   Multidisciplinary, general & others Engineering, computing & technology   Aerospace & aeronautics engineering   Architecture   Chemical engineering   Civil engineering   Computer science   Electrical & electronics engineering   Energy   Geological, petroleum & mining engineering   Materials science & engineering   Mechanical engineering   Multidisciplinary, general & others Human health sciences   Alternative medicine   Anesthesia & intensive care   Cardiovascular & respiratory systems   Dentistry & oral medicine   Dermatology   Endocrinology, metabolism & nutrition   Forensic medicine   Gastroenterology & hepatology   General & internal medicine   Geriatrics   Hematology   Immunology & infectious disease   Laboratory medicine & medical technology   Neurology   Oncology   Ophthalmology   Orthopedics, rehabilitation & sports medicine   Otolaryngology   Pediatrics   Pharmacy, pharmacology & toxicology   Psychiatry   Public health, health care sciences & services   Radiology, nuclear medicine & imaging   Reproductive medicine (gynecology, andrology, obstetrics)   Rheumatology   Surgery   Urology & nephrology   Multidisciplinary, general & others Law, criminology & political science   Civil law   Criminal law & procedure   Criminology   Economic & commercial law   European & international law   Judicial law   Metalaw, Roman law, history of law & comparative law   Political science, public administration & international relations   Public law   Social law   Tax law   Multidisciplinary, general & others Life sciences   Agriculture & agronomy   Anatomy (cytology, histology, embryology...) & physiology   Animal production & animal husbandry   Aquatic sciences & oceanology   Biochemistry, biophysics & molecular biology   Biotechnology   Entomology & pest control   Environmental sciences & ecology   Food science   Genetics & genetic processes   Microbiology   Phytobiology (plant sciences, forestry, mycology...)   Veterinary medicine & animal health   Zoology   Multidisciplinary, general & others Physical, chemical, mathematical & earth Sciences   Chemistry   Earth sciences & physical geography   Mathematics   Physics   Space science, astronomy & astrophysics   Multidisciplinary, general & others Social & behavioral sciences, psychology   Animal psychology, ethology & psychobiology   Anthropology   Communication & mass media   Education & instruction   Human geography & demography   Library & information sciences   Neurosciences & behavior   Regional & inter-regional studies   Social work & social policy   Sociology & social sciences   Social, industrial & organizational psychology   Theoretical & cognitive psychology   Treatment & clinical psychology   Multidisciplinary, general & others     Showing results 1101 to 1200 of 61867     7 8 9 10 11 12 13 14 15 16 17     Baelo Claudia dans l'Antiquité tardive: L'occupation du secteur sud-est du forum entre les IIIe et VIe sièclesBrassous, Laurent; Deru, Xavier ; Rodríguez Gutiérrez, Oliva et alin Melanges de la Casa de Velazquez (2017), 47(1), 167-200Les recherches archéologiques conduites au sud-est du forum de la ville romaine de Baelo claudia ont permis de mettre au jour au-dessus du secteur monumental, plusieurs phases de transformation, d’abandon ... [more ▼]Les recherches archéologiques conduites au sud-est du forum de la ville romaine de Baelo claudia ont permis de mettre au jour au-dessus du secteur monumental, plusieurs phases de transformation, d’abandon et de réoccupation entre les IIIe et VIe s. Les structures découvertes ainsi que le nombreux mobilier qui leur était associé (monnaies, céramique, verre, métal, faune, etc.) fournissent un éclairage nouveau sur l’histoire et la nature de l’agglomération dans l’antiquité tardive, qui entre la fin du IVe s. et son abandon définitif au VIe s. ressemble moins à une ville qu’à un gros village. [less ▲]Detailed reference viewed: 53 (6 ULiège) Microfossils from the late Mesoproterozoic – early Neoproterozoic Atar/El Mreïti Group, Taoudeni Basin, Mauritania, northwestern AfricaBeghin, Jérémie ; Storme, Jean-Yves; Blanpied, Christian et alin Precambrian Research (2017), 291Detailed reference viewed: 29 (5 ULiège) Usefulness of multi-breed models in genetic evaluation of direct and maternal calving ease in Holstein and Belgian Blue Walloon purebreds and crossbredsVanderick, Sylvie ; Gillon, Alain; Glorieux, Géry et alin Livestock Science (2017), 198The objective of this study was to verify the feasibility of a joint genetic evaluation system for calving ease trait of Belgian Blue (BBB) and Holstein (HOL) Walloon cattle based on data of purebred and ... [more ▼]The objective of this study was to verify the feasibility of a joint genetic evaluation system for calving ease trait of Belgian Blue (BBB) and Holstein (HOL) Walloon cattle based on data of purebred and crossbred animals. Variance components and derived genetic parameters for purebred BBB and HOL animals were estimated by using single-breed linear animal models. This analysis showed clear genetic differences between breeds. Estimates of direct and maternal heritabilities (± standard error) were 0.34 (±0.02) and 0.09 (±0.01) for BBB, respectively, but only 0.09 (±0.01) and 0.04 (±0.01) for HOL, respectively. Moreover, a significant negative genetic correlation between direct and maternal effects was obtained in both breeds: −0.46 (±0.04) for BBB and −0.29 (±0.11) for HOL. Variance components and derived genetic parameters for purebred BBB and HOL and crossbred BBB ×× HOL cattle were then estimated by using two multi-breed linear animal models: a multi-breed model based on a random regression test-day model (Model MBV), and a multi-breed model based on the random regression multi-breed model (Model MBSM). Both multi-breed models use different functions of breed proportions as random regressions, thereby enabling modelling different additive effects according to animal's breed composition. The main difference between these models is the way in which relationships between breeds are accounted for in the genetic (co)variance structure. Genetic parameters differed between single-breed and multi-breed analysis, but are similar to the literature. For BBB, estimates of direct and maternal heritabilities (±SE) were 0.45 (±0.07) and 0.08 (±0.01) by using Model MBV, and 0.45 (±0.08) and 0.09 (±0.02) for Model MBSM, respectively. For HOL, these estimates were 0.18 (±0.04) and 0.05 (±0.01) using Model MBV, and 0.16 (±0.04) and 0.05 (±0.01) for Model MBSM, respectively. Reliability gains (up to 25%) indicated that the use of crossbred data in the multi-breed models had a positive influence on the estimation of genetic merit of purebred animals. A slight re-ranking of purebred sires and maternal grandsires was observed between single-breed and multi-breed models. Moreover, both multi-breed models can be considered as quasi-equivalent models because they performed almost equally well with respect to MSE and correlations, for purebred and crossbred animals. [less ▲]Detailed reference viewed: 43 (20 ULiège) An investigation into the fraction of particle accelerators among colliding-wind binaries. Towards an extension of the catalogueDe Becker, Michaël ; Benaglia, Paula; Romero, Gustavo E. et alin Astronomy and Astrophysics (2017), 600Particle-accelerating colliding-wind binaries (PACWBs) are multiple systems made of early-type stars able to accelerate particles up to relativistic velocities. The relativistic particles can interact ... [more ▼]Particle-accelerating colliding-wind binaries (PACWBs) are multiple systems made of early-type stars able to accelerate particles up to relativistic velocities. The relativistic particles can interact with different fields (magnetic or radiation) in the colliding-wind region and produce non-thermal emission. In many cases, non-thermal synchrotron radiation might be observable and thus constitute an indicator of the existence of a relativistic particle population in these multiple systems. To date, the catalogue of PACWBs includes about 40 objects spread over many stellar types and evolutionary stages, with no clear trend pointing to privileged subclasses of objects likely to accelerate particles. This paper aims at discussing critically some criteria for selecting new candidates among massive binaries. The subsequent search for non-thermal radiation in these objects is expected to lead to new detections of particle accelerators. On the basis of this discussion, some broad ideas for observation strategies are formulated. At this stage of the investigation of PACWBs, there is no clear reason to consider particle acceleration in massive binaries as an anomaly or even as a rare phenomenon. We therefore consider that several PACWBs will be detected in the forthcoming years, essentially using sensitive radio interferometers which are capable of measuring synchrotron emission from colliding-wind binaries. Prospects for high-energy detections are also briefly addressed. [less ▲]Detailed reference viewed: 12 (3 ULiège) Siblings and the coming out process: a comparative case studyHaxhe, Stéphanie ; Cerezo, Alison; Bergfeld, Jeanette et alin Journal of Homosexuality (2017), 64Detailed reference viewed: 58 (9 ULiège) Vitamin D supplementation in the prevention and management of major chronic diseases not related to mineral homeostasis in adults: research for evidence and a scientific statement from the European society for clinical and economic aspects of osteoporosis and osteoarthritis (ESCEO)Cianferotti, Luisella; Bertoldo, Francesco; Bischoff-Ferrari, Heike et alin Endocrine (2017), 56(2), 245-61Introduction Optimal vitamin D status promotes skeletal health and is recommended with specific treatment in individuals at high risk for fragility fractures. A growing body of literature has provided ... [more ▼]Introduction Optimal vitamin D status promotes skeletal health and is recommended with specific treatment in individuals at high risk for fragility fractures. A growing body of literature has provided indirect and some direct evidence for possible extraskeletal vitamin D-related effects. Purpose and Methods Members of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis have reviewed the main evidence for possible proven benefits of vitamin D supplementation in adults at risk of or with overt chronic extra-skeletal diseases, providing recommendations and guidelines for future studies in this field. Results and conclusions Robust mechanistic evidence is available from in vitro studies and in vivo animal studies, usually employing cholecalciferol, calcidiol or calcitriol in pharmacologic rather than physiologic doses. Although many cross-sectional and prospective association studies in humans have shown that low 25-hydroxyvitamin D levels (i.e., <50 nmol/L) are consistently associated with chronic diseases, further strengthened by a dose-response relationship, several meta-analyses of clinical trials have shown contradictory results. Overall, large randomized controlled trials with sufficient doses of vitamin D are missing, and available small to moderate-size trials often included people with baseline levels of serum 25-hydroxyvitamin D levels >50 nmol/L, did not simultaneously assess multiple outcomes, and did not report overall safety (e.g., falls). Thus, no recommendations can be made to date for the use of vitamin D supplementation in general, parental compounds, or non-hypercalcemic vitamin D analogs in the prevention and treatment of extra-skeletal chronic diseases. Moreover, attainment of serum 25-hydroxyvitamin D levels well above the threshold desired for bone health cannot be recommended based on current evidence, since safety has yet to be confirmed. Finally, the promising findings from mechanistic studies, large cohort studies, and small clinical trials obtained for autoimmune diseases (including type 1 diabetes, multiple sclerosis, and systemic lupus erythematosus), cardiovascular disorders, and overall reduction in mortality require further confirmation. [less ▲]Detailed reference viewed: 33 (8 ULiège) Overtopping induced failure of non-cohesive, homogenous fluvial dikesRifai, Ismail ; Erpicum, Sébastien ; Archambeau, Pierre et alin Water Resources Research (2017), 53(4), 33733386Accurate predictions of breach characteristics are necessary to reliably estimate the outflow hydrograph and the resulting inundation close to fluvial dikes. Laboratory experiments on the breaching of ... [more ▼]Accurate predictions of breach characteristics are necessary to reliably estimate the outflow hydrograph and the resulting inundation close to fluvial dikes. Laboratory experiments on the breaching of sand-filled fluvial dikes were performed, considering a flow parallel to the dike axis. The breach was triggered by overtopping of the dike crest. A detailed monitoring of the transient evolution of the breach geometry was conducted, providing key insights into the gradual and complex processes involved in fluvial dike failure. The breach develops in two phases: (1) the breach becomes gradually wider and deeper eroding on the downstream side along the main channel, and (2) breach widening controlled by side slope failures, continuing in the downstream direction only. Increasing the inflow discharge in the main channel, the breach formation time decreases significantly and the erosion occurs preferentially on the downstream side. The downstream boundary condition has a strong influence on the breach geometry and the resulting outflow hydrograph. [less ▲]Detailed reference viewed: 57 (5 ULiège) 18-Fluoro-deoxyglucose uptake in inflammatory hepatic adenoma: A case report.Liu, Willy; Delwaide, Jean ; BLETARD, Noëlla et alin World Journal of Hepatology (2017), 9(11), 562-566Positron emission tomography computed tomography (PET-CT) using 18-Fluoro-deoxyglucose (18FDG) is an imaging modality that reflects cellular glucose metabolism. Most cancers show an uptake of 18FDG and ... [more ▼]Positron emission tomography computed tomography (PET-CT) using 18-Fluoro-deoxyglucose (18FDG) is an imaging modality that reflects cellular glucose metabolism. Most cancers show an uptake of 18FDG and benign tumors do not usually behave in such a way. The authors report herein the case of a 38-year-old female patient with a past medical history of cervical intraepithelial neoplasia and pheochromocytoma, in whom a liver lesion had been detected with PET-CT. The tumor was laparoscopically resected and the diagnosis of inflammatory hepatic adenoma was confirmed. This is the first description of an inflammatory hepatic adenoma with an 18FDG up-take. [less ▲]Detailed reference viewed: 34 (9 ULiège) Déploiement de dispositifs numériques au sein de nouvelles formes d’organisation : de l’émergence à la stabilisationJemine, Grégory in Sociologies Pratiques (2017), 34(1), 49-59De plus en plus d’organisations du secteur des services s’équipent aujourd’hui de dispositifs numériques variés qui modifient les contextes et les contenus du travail. Ces outils sont présentés comme des ... [more ▼]De plus en plus d’organisations du secteur des services s’équipent aujourd’hui de dispositifs numériques variés qui modifient les contextes et les contenus du travail. Ces outils sont présentés comme des ingrédients indispensables des modes managériales actuelles qui permettraient à divers dispositifs organisationnels promouvant la flexibilité et la mobilité de s’incarner. La présente contribution propose une étude des ressorts de l’émergence et de la stabilisation de ces dispositifs numériques qui émergent dans le cours de transformations organisationnelles. Nous montrons comment, dans une compagnie d’assurances, les dispositifs numériques sont mobilisés pour répondre à une volonté de « modernisation » de l’organisation et d’optimisation de l’espace de travail. [less ▲]Detailed reference viewed: 37 (11 ULiège) Etude comparative des profils de dissolution in vitro de quinine sulfate générique et princeps en utilisant la Chromatographie Liquide Haute PerformanceMbinze Kindenge, Jérémie ; Diallo, Tediane; Yemoa, Loconon et alin Médecine d'Afrique Noire (2017), 64Introduction : La quinine est une molécule préconisée pour le traitement du paludisme dans les régions où les souches de P. falciparum sont polyrésistantes. Face à l’importante utilisation de ses ... [more ▼]Introduction : La quinine est une molécule préconisée pour le traitement du paludisme dans les régions où les souches de P. falciparum sont polyrésistantes. Face à l’importante utilisation de ses médicaments génériques d’une part, et au fléau des médicaments de qualité inférieure d’autre part, il devient plus que nécessaire d’appuyer les données des tests physico-chimiques par celles de dissolution in vitro dont l’évaluation et la comparaison des cinétiques permettra de prédire le comportement in vivo du principe actif et par conséquent l’efficacité du médicament générique. L’objectif de la présente étude est de réaliser une étude comparative de la cinétique de dissolution d’un princeps et d’un générique à base de quinine comprimé 300 mg commercialisés à Kinshasa. Matériels et méthodes : L’étude a été réalisée en utilisant trois milieux de pH différents (1,2 - 4,5 - 6,8) tels que recommandés par l’Agence Européenne de Médicament et en se servant d’un appareil de dissolution, tandis que l’équipement de chromatographie liquide à haute performance couplée à un détecteur à barrette de diodes a été utilisé pour la quantification. La méthode statistique fit factor a été appliquée pour comparer les résultats de dosage de la quinine dans les trois milieux tout en ayant évalué le biais à différents temps de dissolution. Résultats : Les différents échantillons de médicaments générique et princeps ont été conformes quant à l’identification et au dosage de la quinine, par contre leurs cinétiques de dissolution étaient non similaires. Discussion : Ceci pourrait avoir une influence sur l’efficacité du produit générique et la sécurité des consommateurs, dénotant l’importance d’examiner les profils de dissolution des génériques avant toute autorisation de mise sur le marché plus particulièrement dans les pays en voie de développement. [less ▲]Detailed reference viewed: 113 (42 ULiège) Le Fichier écologique des essences, version 2.0Petit, S.; Claessens, Hugues ; Vincke, C. et alin FORÊT.NATURE (2017), (143), 12-19Après plus de 25 ans d’utilisation, le Fichier écologique des essences méritait une révision en profondeur. Il a été remis au goût du jour grâce à l’Accord-cadre de recherches et vulgarisation forestières ... [more ▼]Après plus de 25 ans d’utilisation, le Fichier écologique des essences méritait une révision en profondeur. Il a été remis au goût du jour grâce à l’Accord-cadre de recherches et vulgarisation forestières et par les équipes de recherches de l’Ulg-GxABT et de l’UCL, avec l’appui de Forêt Wallonne. Fruit d’une collaboration entre chercheurs et gestionnaires de terrain, il repose sur un large travail de recherche bibliographique, adapté au contexte wallon grâce aux membres d’un groupe de travail composé de scientifiques et de forestiers. Il a évolué pour répondre aux attentes de la société et prône une forêt multifonctionnelle et résiliente face aux changements climatiques. Disponible sous format web, il facilite la prise en main par les utilisateurs et les guide vers la meilleure adaptation entre les essences et les stations, gage d’un écosystème pleinement fonctionnel, résilient et répondant aux besoins actuels de la société. [less ▲]Detailed reference viewed: 29 (3 ULiège) Deciphering the Multifactorial Susceptibility of Mucosal Junction Cells to HPV Infection and Related CarcinogenesisHerfs, Michael ; Soong, Thing R; Delvenne, Philippe et alin Viruses (2017), 9 (4)Detailed reference viewed: 12 (3 ULiège) Use of cis-atracurium to maintain moderate neuromuscular blockade in experimental pigsTutunaru, Alexandru-Cosmin ; Dupont, Julien ; Serteyn, Didier et alin Veterinary Anaesthesia & Analgesia (2017)Detailed reference viewed: 20 (3 ULiège) Out of the ground: two coexisting fossorial toad species differ in their emergence and movement patternsSzékely, Diana ; Cogalniceanu, Dan; Székely, Paul et alin Zoology (2017), 121Understanding the way species with similar niches can coexist is a challenge in ecology.The niche partitioning hypothesis has received much support, positing that species can exploit available resources ... [more ▼]Understanding the way species with similar niches can coexist is a challenge in ecology.The niche partitioning hypothesis has received much support, positing that species can exploit available resources in different ways. In the case of secretive species, behavioural mechanisms of partitioning are still poorly understood. This is especially true for fossorial frogs because individuals hide underground by day and are active only during the night. We investigated the nocturnal activity and tested the niche partitioning hypothesis in two syntopic fossorial spadefoot toads (Pelobates fuscus and P. syriacus) by examining interspecific variation in emergence from the soil. We employed a night vision recording system combined with video-tracking analyses in a replicated laboratory setting to quantify individual movement patterns, a procedure that has not been used until now to observe terrestrial amphibians. Most individuals appeared on the surface every night and returned to their original burrow (about 60% of the times), or dug a new one around morning. There was a large temporal overlap between the two species. However, P. syriacus was significantly more active than P. fuscus in terms of total distance covered and time spent moving, while P. fuscus individuals left their underground burrow more frequently than P. syriacus. Consequently, P. fuscus adopted more of a sit-and-wait behaviour compared to P. syriacus, and this could facilitate their coexistence. The use of night video-tracking technologies offered the advantage of individually tracking these secretive organisms during their nocturnal activity period and getting fine-grain data to understand their movement patterns. [less ▲]Detailed reference viewed: 66 (29 ULiège) Het Belgische interneringsbeleid als een voorbeeld van hybride bestuurPans, Maurice; Darcis, Coralie ; Leys, Mark et alin Tijdschrift voor Bestuurswetenschappen en Publiekrecht (2017), 4Het domein van de zorg voor geïnterneerde personen kent internationaal een omslag. Naast de “criminalisering” van personen met een psychiatrische stoornis die criminele feiten begaan, ontwikkelen er zich ... [more ▼]Het domein van de zorg voor geïnterneerde personen kent internationaal een omslag. Naast de “criminalisering” van personen met een psychiatrische stoornis die criminele feiten begaan, ontwikkelen er zich nieuwe visies en zorgperspectieven op de kwaliteit van leven en de re-integratie in de maatschappij van zowel personen met psychische kwetsbaarheid als geïnterneerde personen. Tot zeer recent werden geïnterneerde personen bijna exclusief benaderd als personen die misdaden of misdrijven hebben gepleegd waar ze door hun psychische stoornis niet voor verantwoordelijk konden worden gesteld. De onderliggende logica van de aanpak was sterk geënt op een model waarbij opsluiting en isolatie van de maatschappij centraal stonden omwille van misdaad. Geïnterneerde personen werden om die reden opgesloten in een gevangenissysteem volgens een justitiële benadering. Het behandelings- en zorgperspectief raakte hierbij ondergesneeuwd. De “criminalisering” van personen met psychische stoornissen heeft in België historisch geleid tot inadequate aanpak en begeleiding van deze groep patiënten. Meerdere veroordelingen van de Belgische Staat door het Europees Hof voor de Rechten van de Mens (EHRM), overvolle gevangenissen, het gebrek aan somatische en psychiatrische gezondheidszorg binnen gevangenissen en psychiatrische annexen en aanbevelingen van het Europees Comité voor de Preventie van Foltering en Onmenselijke of Vernederende Behandeling of Bestraffing (CPT) zijn directe aanleidingen voor het Masterplan Internering (juni 2016) en de wet van 5 mei 2014 betreffende de internering van personen . In deze bijdrage staan we stil bij het Masterplan Internering van 2016 en de nieuwe Interneringswet van 5 mei 2014. We proberen te duiden op welke manier in beide bronnen randvoorwaarden worden gecreëerd voor een hybride bestuursvorm in de sector. We staan kort stil bij beleidsmatige en juridische ontwikkelingen die vooraf gingen. [less ▲]Detailed reference viewed: 70 (8 ULiège) Une mata-analyse des degrés de certitude exprimés en motsLeclercq, Dieudonné in Evaluer : Journal International de Recherche en Education et Formation (2017), 2(3), 69-105Asking to students to add a confidence degree to each of their responses to a test is rather rare, and the large majority of those who practice that use verbal scales such as “weakly sure”, “sure” ... [more ▼]Asking to students to add a confidence degree to each of their responses to a test is rather rare, and the large majority of those who practice that use verbal scales such as “weakly sure”, “sure”, “strongly sure”, etc. instead of probabilities or percentages of chances. My hypothesis is that consists in introducing, from the beginning, an enormous random error of measurement since there exist large differences in the interpretation (the translation) into percentages of the word used in verbal scales. I demonstrated this in two experiences (Leclercq, 2016), one in context and one context free. A strong convergence appear in the results of the two experiences in terms of communicational fog produced by words in place of percentages (from 0% to 100%). Variation Ranges (VR) of translations of words into percentages have a modal value of 40% and standard deviations (SD) from 10% to 15%. Therefore my hypothesis is confirmed by these two experiences, but what does the specialized literature say? In a first part of the present article I have browsed many reviews and books with the purpose to find data that contribute to fight (and kill ?) this habit of using words instead of percentages to express confidence degrees. Therefore I have named my method a “mata” analysis (matar meaning “to kill” in Spanish), that is distinct from meta-analysis, as will be shown. In the second part of the article, I underline data that help approach what could be the optimal number of numerical degrees (and their exact values) not only in terms of students’ preferences, but mainly in terms of the reliability (measured but the repeatability criterion, i.e; stability in a short period of time) of the declared confidence. [less ▲]Detailed reference viewed: 53 (8 ULiège) On the identification of paedomorphic and overwintering larval newts based on cloacal shape: review and guidelinesDenoël, Mathieu in Current Zoology (2017), 63(2), 165-173Paedomorphosis is an alternative process to metamorphosis in which adults retain larval traits at the adult stage. It is frequent in newts and salamanders, where larvae reach sexual maturity without ... [more ▼]Paedomorphosis is an alternative process to metamorphosis in which adults retain larval traits at the adult stage. It is frequent in newts and salamanders, where larvae reach sexual maturity without losing their gills. However, in some populations, larvae overwinter in water, while remaining immature. These alternative ontogenetic processes are of particular interest in various research fields, but have different causes and consequences, as only paedomorphosis allows metamorphosis to be bypassed before maturity. It is thus relevant to efficiently identify paedomorphs versus overwintering larvae. In this context, the aim of this paper was threefold: firstly, to perform a meta-analysis of the identification procedures carried out in the literature; secondly, to determine the effectiveness of body size to make inferences about adulthood by surveying natural newt populations of Lissotriton helveticus and Ichthyosaura alpestris, and thirdly, to propose easy guidelines for an accurate distinction between large larvae and paedomorphs based on an external sexual trait, which is essential for reproduction — the cloaca. More than half of the studies in the literature do not mention the diagnostic criteria used for determining adulthood. The criteria mentioned were the presence of mature gonads (10%), eggs laid (4%), courtship behaviour (10%), and external morphological sexual traits (39%) including the cloaca (24%). Body-size thresholds should not be used as a proxy for paedomorphosis, because overwintering larvae can reach a larger size than paedomorphs within the same populations. In contrast, diagnosis based on cloacal external morphology is recommended, as it can be processed by the rapid visual assessment of all caught specimens, thus providing straightforward data at the individual level for both sexes. [less ▲]Detailed reference viewed: 193 (65 ULiège) Assessing the effect of pregnancy stage on milk composition of dairy cows using mid-infrared spectraLaine, Aurélie ; Bastin, Catherine; Grelet, Clément et alin Journal of Dairy Science (2017), 100(4), 2863-2876Changes in milk production traits (i.e., milk yield, fat, and protein contents) with the pregnancy stage are well documented. To our knowledge, the effect of pregnancy on the detailed milk composition has ... [more ▼]Changes in milk production traits (i.e., milk yield, fat, and protein contents) with the pregnancy stage are well documented. To our knowledge, the effect of pregnancy on the detailed milk composition has not been studied so far. The mid-infrared (MIR) spectrum reflects the detailed composition of a milk sample and is obtained by a nonexhaustive and widely used method for milk analysis. Therefore, this study aimed to investigate the effect of pregnancy on milk MIR spectrum in addition to milk production traits (milk yield, fat, and protein contents). A model including regression on the number of days pregnant was applied on milk production traits (milk yield, fat, and protein contents) and on 212 spectral points from the MIR spectra of 9,757 primiparous Holstein cows from Walloon herds. Effects of pregnancy stage were expressed on a relative scale (effect divided by the squared root of the phenotypic variance); this allowed comparisons between effects on milk traits and on 212 spectral points. Effect of pregnancy stage on production traits were in line with previous studies indicating that the model accounted well for the pregnancy effect. Trends of the relative effect of the pregnancy stage on the 212 spectral points were consistent with known and observed effect on milk traits. The highest effect of the pregnancy was observed in the MIR spectral region from 968 to 1,577 cm−1. For some specific wavenumbers, the effect was higher than for fat and protein contents in the beginning of the pregnancy (from 30 to 90 or 120 d pregnant). In conclusion, the effect of early pregnancy can be observed in the detailed milk composition through the analysis of the MIR spectrum of bovine milk. Further analyses are warranted to explore deeply the use of MIR spectra of bovine milk for breeding and management of dairy cow pregnancy. [less ▲]Detailed reference viewed: 21 (7 ULiège) D’une victime à l’autre: Posture ou (im)posture victimaire?Garcet, Serge in Revue de la Faculté de Droit de l'Université de Liège (2017), 2017/1Detailed reference viewed: 34 (10 ULiège) Interest of creatine supplementation insoccerMiny, Kevin ; Burrowes, J; Jidovtseff, Boris in Science & Sports (2017), 32(2), 61-72Objectives This review article aimed to summarize the current state of understanding on creatine supplementation for soccer players. In other words, it investigated the beneficial (and potentially ... [more ▼]Objectives This review article aimed to summarize the current state of understanding on creatine supplementation for soccer players. In other words, it investigated the beneficial (and potentially negative) effects of this supplementation on sport-specific skills and performance in soccer players. Furthermore, this article accordingly discussed the safest and most recommended protocols for the consumption of creatine by these athletes. News Studies have shown that creatine supplementation can have positive effects on sprint and vertical jump performances in soccer players. This supplementation may also enhance soccer players’ muscle strength and adaptation to a high-intensity training regimen. Besides, creatine may be able to enhance muscle glycogen (as well as phosphocreatine) storage, reduce oxidative stress, and improve muscular repair and hypertrophy. Interestingly, creatine supplementation does not seem to affect aerobic performance. Prospects and projects Soccer players could take creatine during pre-season training (3 to 5g/day) in order to help them endure a high-intensity training regimen and enhance their muscular strength and adaptation resulting from strength and/or resistance training. A lower dosage (less than 3g/day) might also be sufficient and beneficial during the season in case of fatigue, in order to sustain adequate levels of phosphocreatine and glycogen in the muscles. Occasional intakes (about 3g) before games and/or extenuating practices could also give a physical and mental boost to the players. Conclusion Most of the studies measured the effects of creatine on skills or physical performances in isolation from the true athletic demands of soccer match play. In conclusion, there is still a need for more research in order to determine whether creatine supplementation is ergogenic regarding the (aerobic) capacity to repeat (very) high-intensity actions, more particularly during competitive soccer. [less ▲]Detailed reference viewed: 47 (9 ULiège) "La madone et la putain": Quand les stéréotypes de genres influencent la perception de la légalité des violences sexuelles et le traitement de la réaction sociale à l'égard des femmesGarcet, Serge in Revue de la Faculté de Droit de l'Université de Liège (2017), 2017/1Les illégalités liées au traitement différentiel des genres reposent notamment sur la présence de stéréotypes sexistes. L’article illustre comment les attitudes subjectivement positives à l’égard des ... [more ▼]Les illégalités liées au traitement différentiel des genres reposent notamment sur la présence de stéréotypes sexistes. L’article illustre comment les attitudes subjectivement positives à l’égard des femmes que l’on peut qualifier de stéréotypes sexistes bienveillants influencent tant positivement que négativement la façon dont les femmes sont perçues par le système judiciaire. L’article souligne également au travers des représentations liées aux violences sexuelles l’impact des stéréotypes sexistes hostiles sur la perception de la légalité, de la légitimité perçue du passage à l’acte et du statut des victimes. [less ▲]Detailed reference viewed: 86 (23 ULiège) Decrease in climatic conditions favouring floods in the south-east of Belgium over 1959-2010 using the regional climate model MARWyard, Coraline ; Scholzen, Chloé ; Fettweis, Xavier et alin International Journal of Climatology (2017), 37(5), 27822796The Ourthe River, in the south-east of Belgium, has a catchment area of 3,500 km2 and is one of the main tributaries of the Meuse River. In the Ourthe, most of the flood events occur during winter and ... [more ▼]The Ourthe River, in the south-east of Belgium, has a catchment area of 3,500 km2 and is one of the main tributaries of the Meuse River. In the Ourthe, most of the flood events occur during winter and about 50% of them are due to heavy rainfall events combined to an abrupt melting of the snowpack covering the Ardennes massif during winter. This study aims to determine whether trends in extreme hydroclimatic events generating floods can be detected over the last century in Belgium, where a global warming signal can be observed. Hydroclimatic conditions favourable to floods were reconstructed over 1959- 2010 using the regional climate model MAR (“Modèle Atmosphérique Régional”) forced by the ERA-Interim/ERA-40, the ERA-20C and the NCEP/NCAR-v1 reanalyses. Extreme run-off events, which could potentially generate floods, were detected using run-off caused by precipitation events and snowpack melting from the MAR model. In the validation process, the MAR-driven temperature, precipitation and snow depth were successfully compared to daily weather data over the period 2008-2014 for 20 stations in Belgium. MAR also showed its ability to detect up to 90% of the hydroclimatic conditions which effectively generated observed floods in the Ourthe River over the period 1974- 2010. Conditions favourable to floods in the Ourthe River catchment present a negative trend over the period 1959-2010 as a result of a decrease in snow accumulation and a shortening of the snow season. This trend is expected to accelerate in a warmer climate. However, regarding the impact of the extreme precipitation events evolution on conditions favouring floods, the signal is less clear since the trends depend on the reanalysis used to force the MAR model. [less ▲]Detailed reference viewed: 120 (55 ULiège) Identification of Shiga toxin-producing (STEC) and enteropathogenic (EPEC) Escherichia coli in diarrhoeic calves and comparative genomics of O5 bovine and human STECFakih, Ibrahim; Thiry, Damien ; Duprez, Jean-Noël et alin Veterinary Microbiology (2017), 202Escherichia coli producing Shiga toxins (Stx) and the attaching-effacing (AE) lesion (AE-STEC) are responsible for (bloody) diarrhoea in humans and calves while the enteropathogenic E. coli (EPEC ... [more ▼]Escherichia coli producing Shiga toxins (Stx) and the attaching-effacing (AE) lesion (AE-STEC) are responsible for (bloody) diarrhoea in humans and calves while the enteropathogenic E. coli (EPEC) producing the AE lesion only cause non-bloody diarrhoea in all mammals. The purpose of this study was (i) to identify the pathotypes of enterohaemolysin-producing E. coli isolated between 2009 and 2013 on EHLY agar from less than 2 month-old diarrhoeic calves with a triplex PCR targeting the stx1, stx2, eae virulence genes; (ii) to serotype the positive isolates with PCR targeting the genes coding for ten most frequent and pathogenic human and calf STEC O serogroups; and (iii) to compare the MLSTypes and virulotypes of calf and human O5 AE-STEC after Whole Genome Sequencing using two server databases (www.genomicepidemiology.org). Of 233 isolates, 206 were triplex PCR-positive: 119 AE-STEC (58%), 78 EPEC (38%) and 9 STEC (4%); and the stx1+eae+ AE-STEC (49.5%) were the most frequent. Of them, 120 isolates (84% of AE-STEC, 23% of EPEC, 22% of STEC) tested positive with one O serogroup PCR: 57 for O26 (47.5%), 36 for O111 (30%), 10 for O103 (8%) and 8 for O5 (7%) serogroups. The analysis of the draft sequences of 15 O5 AE-STEC could not identify any difference correlated to the host. As a conclusion, (i) the AE-STEC associated with diarrhoea in young calves still belong to the same serogroups as previously (O5, O26, O111) but the O103 serogroup may be emerging, (ii) the O5 AE-STEC from calves and humans are genetically similar [less ▲]Detailed reference viewed: 49 (16 ULiège) De geregistreerde criminaliteit van jongvolwassenen in Brussel : het belang van de soio-economische contextVanneste, Charlotte ; Ravier, Isabelle; Mahieu, Valentinein Justice & Sécurité/ Justitie & Veiligheig, (2017)Detailed reference viewed: 16 (0 ULiège) L’ÉCHOGRAPHIE EN SITUATION DE SOIN : STÉTHOSCOPE DU FUTUR POUR LE MÉDECIN GÉNÉRALISTE ?Henrard, Gilles ; Froidcoeur, Xavier ; Schoffeniels, Colombe et alin Revue Médicale de Liège (2017)Ultrasound is presently emerging not only as a specialist-delegated diagnostic procedure, but also as a tool used by clinicians for guiding decision. If this paradigm shift has taken roots in places like ... [more ▼]Ultrasound is presently emerging not only as a specialist-delegated diagnostic procedure, but also as a tool used by clinicians for guiding decision. If this paradigm shift has taken roots in places like emergency departments, initiatives are also set up here and there in general practice. The aim of this article is , through a literature review, to identify possible indications of ultrasound performed by the general practitioner and to initiate a discussion about the obstacles and opportunities associated with its introduction in Belgian General Practice settings. [less ▲]Detailed reference viewed: 122 (16 ULiège) Les retardateurs de flamme bromés : impact sur l'environnement et la santé des individus exposésDufour, Patrice ; Charlier, Corinne in Annales de Biologie Clinique (2017), 75(2), 146-157Depuis l’antiquité, l’homme utilise des moyens chimiques pour protéger ses biens des incendies. Efficaces et faciles d’emploi, les retardateurs de flamme bromés sont utilisés depuis plusieurs décennies de ... [more ▼]Depuis l’antiquité, l’homme utilise des moyens chimiques pour protéger ses biens des incendies. Efficaces et faciles d’emploi, les retardateurs de flamme bromés sont utilisés depuis plusieurs décennies de façon massive dans l’industrie du plastique. À l’instar d’autres composés organohalogénés, les retardateurs de flamme bromés sont très persistants dans l’environnement et capables de s’accumuler le long de la chaîne alimentaire. De nombreux auteurs ont mis en évidence leur présence dans notre environnement, chez différentes espèces animales mais également dans le sérum humain. Plus inquiétant encore, l’homme est exposé à ces polluants dès la grossesse et par la suite via le lait maternel. Cette exposition pourrait avoir des conséquences sur notre santé. De nombreuses études in vitro, in vivo ou épidémiologiques ont mis en lumière une influence néfaste des retardateurs de flamme bromés sur notre système endocrinien, principalement au niveau de la fonction thyroïdienne mais également de la reproduction, du neurodéveloppement chez l’enfant et du métabolisme avec un risque accru de développer un diabète. Si une certaine prise de conscience a déjà eu lieu au niveau des autorités et de certaines grandes entreprises, de nouvelles études sont nécessaires pour confirmer les tendances déjà dégagées, élucider les mécanismes sous-jacents et déterminer s’il existe des synergies avec d’autres polluants tels que par exemple les PCB. [less ▲]Detailed reference viewed: 27 (4 ULiège) Deposition of ZnO based thin films by atmospheric pressure spatial atomic layer deposition for application in solar cellsNguyen, Viet; Avelas Resende, João ; Jimenez et alin Journal of Renewable and Sustainable Energy (2017)Detailed reference viewed: 33 (4 ULiège) Plantations et bornage : prérogatives d'un emphytéotePopa, Ruxandra in Journal des Juges de Paix = Tijdschrift van de Vrederecters (2017), 3-4(2017), Detailed reference viewed: 28 (2 ULiège) ROLE OF IMAGING IN LEFT ATRIAL APPENDAGE OCCLUSIONLEMPEREUR, Mathieu ; AMINIAN, Adel; DULGHERU, Raluca Elena et alin international journal of cardiovascular practice (2017), 2(2), 33-43Detailed reference viewed: 28 (2 ULiège) High concordance of Pfdhfr and Pfdhps genotypes between matched peripheral and placental isolates of delivered women in Bobo-Dioulasso, Burkina FasoCissé, Mamoudou; Awandare, Gordon; Some, Fabrice et alin Annals of Parasitology (2017), 63(2), 111-116Whether maternal peripheral parasites constitute a representative sample of the overall population infecting the individual, remains unknown in Burkina Faso. We therefore compared Pfdhfr and Pfdhps ... [more ▼]Whether maternal peripheral parasites constitute a representative sample of the overall population infecting the individual, remains unknown in Burkina Faso. We therefore compared Pfdhfr and Pfdhps génotypes between matched peripheral and placental isolates. PCR-restriction fragment length polymorphism (PCR-RFLP) analysis of polymorphic codons of the Pfdhfr gene (51, 59, 108 and 164) and the Pfdhps gene (437 and 540) was performed in 18 matched peripheral and placental dried blood spots of delivered women in Bobo-Dioulasso. Both Pfdhfr and Pfdhps genes were successfully genotyped in 94.4% (17/18) of the matched samples. Only 8.8% (3/34) of génotypes were of the wild type, while 20.6% (7/34), 20.6% (7/34), 23.5% (8/34) and 26.5% (9/34) comprised one, two, three and four mutations, respectively. None of the samples carried both Pfdhfr I164L and Pfdhps K540E mutations. A concordance of 82.4% was observed in matched samples for both the Pfdhfr and Pfdhps genes. Setting placental allèles as the reference, a concordance of 100% was obtained with Pfdhfr mutation S108N, Pfdhfr mutation C59R+S108N, and Pfdhfr mutation N51I+C59R +S108N, respectively. Likewise, a concordance of 85.7% was observed with the Pfdhps mutation A437G. For epidemiological purposes, peripheral blood Pfdhfr and Pfdhps genotyping is sufficient for monitoring SP resistant molecular markers in pregnant women. [less ▲]Detailed reference viewed: 23 (6 ULiège) Size fractionation as a tool for separating charcoal of different fuel source and recalcitrance in the wildfire ash layerMastrolonardo, Giovanni in Science of the Total Environment (2017), 595Charcoal is a heterogeneous material exhibiting a diverse range of properties. This variability represents a serious challenge in studies that use the properties of natural charcoal for reconstructing ... [more ▼]Charcoal is a heterogeneous material exhibiting a diverse range of properties. This variability represents a serious challenge in studies that use the properties of natural charcoal for reconstructing wildfires history in terrestrial ecosystems. In this study, we tested the hypothesis that particle size is a sufficiently robust indicator for separating forest wildfire combustion products into fractions with distinct properties. For this purpose, we examined two different forest environments affected by contrasting wildfires in terms of severity: an eucalypt forest in Australia, which experienced an extremely severe wildfire, and a Mediterranean pine forest in Italy, which burned to moderate severity. We fractionated the ash/charcoal layers collected on the ground into four size fractions (>2, 2–1, 1–0.5, <0.5 mm) and analysed them for mineral ash content, elemental composition, chemical structure (by IR spectroscopy), fuel source and charcoal reflectance (by reflected-light microscopy), and chemical/thermal recalcitrance (by chemical and thermal oxidation). At both sites, the finest fraction (<0.5 mm) had, by far, the greatest mass. The C concentration and C/N ratio decreased with decreasing size fraction, while pH and the mineral ash content followed the opposite trend. The coarser fractions showed higher contribution of amorphous carbon and stronger recalcitrance. We also observed that certain fuel types were preferentially represented by particular size fractions. We conclude that the differences between ash/charcoal size fractions were most likely primarily imposed by fuel source and secondarily by burning conditions. Size fractionation can therefore serve as a valuable tool to characterise the forest wildfire combustion products, as each fraction displays a narrower range of properties than the whole sample. We propose the mineral ash content of the fractions as criterion for selecting the appropriate number of fractions to analyse. [less ▲]Detailed reference viewed: 10 (4 ULiège) DFT investigation of the reaction mechanism for the guanidine catalyzed ring-opening of cyclic carbonates by aromatic and alkyl-aminesAlves, Margot ; Méreau, Raphaël; Grignard, Bruno et alin RSC Advances (2017), 7(31), 18993-19001The guanidine catalysed aminolysis of propylene carbonate has been investigated using the density functional theory (DFT) and highlights that different reaction pathways are involved depending on the ... [more ▼]The guanidine catalysed aminolysis of propylene carbonate has been investigated using the density functional theory (DFT) and highlights that different reaction pathways are involved depending on the aromatic or aliphatic nature of the amine. The structural ability of 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) to simultaneously give and receive protons was demonstrated by a detailed mechanistic investigation. The bifunctional activity (base/H-bond donor) of TBD significantly reduces the Gibbs energy of the reaction and allows understanding its higher efficiency compared to its methyl counterpart (MTBD). [less ▲]Detailed reference viewed: 36 (7 ULiège) Macro-nutrient concentrations in Antarctic pack ice: Overall patterns and overlooked processesFripiat, François ; Meiners, K.M.; Vancoppenolle, M. et alin Elementa: Science of the Anthropocene (2017), 5(13), Antarctic pack ice is inhabited by a diverse and active microbial community reliant on nutrients for growth. Seeking patterns and overlooked processes, we performed a large-scale compilation of macro ... [more ▼]Antarctic pack ice is inhabited by a diverse and active microbial community reliant on nutrients for growth. Seeking patterns and overlooked processes, we performed a large-scale compilation of macro-nutrient data (hereafter termed nutrients) in Antarctic pack ice (306 ice-cores collected from 19 research cruises). Dissolved inorganic nitrogen and silicic acid concentrations change with time, as expected from a seasonally productive ecosystem. In winter, salinity-normalized nitrate and silicic acid concentrations (C*) in sea ice are close to seawater concentrations (Cw), indicating little or no biological activity. In spring, nitrate and silicic acid concentrations become partially depleted with respect to seawater (C* < Cw), commensurate with the seasonal build-up of ice microalgae promoted by increased insolation. Stronger and earlier nitrate than silicic acid consumption suggests that a significant fraction of the primary productivity in sea ice is sustained by flagellates. By both consuming and producing ammonium and nitrite, the microbial community maintains these nutrients at relatively low concentrations in spring. With the decrease in insolation beginning in late summer, dissolved inorganic nitrogen and silicic acid concentrations increase, indicating imbalance between their production (increasing or unchanged) and consumption (decreasing) in sea ice. Unlike the depleted concentrations of both nitrate and silicic acid from spring to summer, phosphate accumulates in sea ice (C* > Cw). The phosphate excess could be explained by a greater allocation to phosphorus-rich biomolecules during ice algal blooms coupled with convective loss of excess dissolved nitrogen, preferential remineralization of phosphorus, and/or phosphate adsorption onto metal-organic complexes. Ammonium also appears to be efficiently adsorbed onto organic matter, with likely consequences to nitrogen mobility and availability. This dataset supports the view that the sea ice microbial community is highly efficient at processing nutrients but with a dynamic quite different from that in oceanic surface waters calling for focused future investigations. [less ▲]Detailed reference viewed: 20 (2 ULiège) Simultaneous analysis of nucleobases, nucleosides and ginsenosides in ginseng extracts using supercritical fluid chromatography coupled with single quadrupole mass spectrometryHuang, Yang ; Zhang, Tingting; Zhao, Yumei et alin Journal of Pharmaceutical and Biomedical Analysis (2017), 144(213), 219Nucleobases, nucleosides and ginsenosides, which have a significant impact on the physiological activity of organisms, are reported to be the active components of ginseng, while they are less present in ... [more ▼]Nucleobases, nucleosides and ginsenosides, which have a significant impact on the physiological activity of organisms, are reported to be the active components of ginseng, while they are less present in ginseng extracts. Few analytical methods have been developed so far to simultaneously analyze these three classes of compounds with different polarities present in ginseng extracts. In the present study, a simple and efficient analytical method was successfully developed for the simultaneous separation of 17 nucleobases, nucleosides and ginsenosides in ginseng extracts using supercritical fluid chromatography coupled with single quadrupole mass spectrometry (SFC-MS). The effect of various experimental factors on the separation performance, such as the column type, temperature and backpressure, the type of modifier and additive, and the concentration of make-up solvent were systematically investigated. Under the selected conditions, the developed method was successfully applied to the quality evaluation of 14 batches of ginseng extracts from different origins. The results obtained for the different batches indicate that this method could be employed for the quality assessment of ginseng extracts [less ▲]Detailed reference viewed: 20 (1 ULiège) Benchmarking carbon fluxes of the ISIMIP2a biome modelsChang, Jinfeng; Ciais, Philippe; Wang, Xuhui et alin Environmental Research Letters (2017), 12Detailed reference viewed: 28 (7 ULiège) VARIATIONS OF TREE RING WIDTH AND CHEMICAL COMPOSITION OF WOOD OF PINE GROWING IN THE AREA NEARBY CHEMICAL FACTORIESSENSUŁA, BARBARA; WILCZYŃSKI, SŁAWOMIR; MONIN, LAURENCE et alin Geochronometria : Journal on Methods & Applications of Absolute Chronology (2017), 44This study reports the variation of tree-ring widths and annual variation of concentration of metals (Na, Mg, Fe, Ni, Cu, Zn, Pb) in pine growing nearby chemical factories. The conifers (Pinus silvestris ... [more ▼]This study reports the variation of tree-ring widths and annual variation of concentration of metals (Na, Mg, Fe, Ni, Cu, Zn, Pb) in pine growing nearby chemical factories. The conifers (Pinus silvestris L.) investigated in this study covered the time span from 1920s to 2010 AD. Tree-ring widths were measured, dated and rechecked using the COFECHA. Radial trace-element profiles were determined by Laser Ablation Inductively Coupled Plasma Mass Spectrometry. The combined usage of tree ring width and chemical composition of wood provides historic records of anthropogenic im- pact on the environment and allows identifying the behavior adaptation of trees to the pollution. Data of pine tree cores collected from the sites nearby chemical factories show increasing levels of pollu- tion linked to the increasing of industrial activities in Poland and subsequent dust fallout around the site. This study evidences that tree rings can be used as archives of past environmental contamination. [less ▲]Detailed reference viewed: 13 (1 ULiège) Promoting vaginal distribution of E7 and MCL-1 siRNA-silencing nanoparticles for cervical cancer treatmentLechanteur, Anna ; Furst, Tania; Delvenne, Philippe et alin Molecular Pharmaceutics (2017)Detailed reference viewed: 20 (8 ULiège) On-sky performance of the QACITS pointing control technique with the Keck/NIRC2 vortex coronagraphHuby, Elsa ; Bottom, Michael; Femenia, Bruno et alin Astronomy and Astrophysics (2017), 600A vortex coronagraph is now available for high contrast observations with the Keck/NIRC2 instrument at L band. Reaching the optimal performance of the coronagraph requires fine control of the wavefront ... [more ▼]A vortex coronagraph is now available for high contrast observations with the Keck/NIRC2 instrument at L band. Reaching the optimal performance of the coronagraph requires fine control of the wavefront incident on the phase mask. In particular, centering errors can lead to significant stellar light leakage that degrades the contrast performance and prevents the observation of faint planetary companions around the observed stars. It is thus critical to correct for the possible slow drift of the star image from the phase mask center, generally due to mechanical flexures induced by temperature and/or gravity field variation, or to misalignment between the optics that rotate in pupil tracking mode. A control loop based on the QACITS algorithm for the vortex coronagraph has thus been developed and deployed for the Keck/NIRC2 instrument. This algorithm executes the entire observing sequence, including the calibration steps, initial centering of the star on the vortex center and stabilisation during the acquisition of science frames. On-sky data show that the QACITS control loop stabilizes the position of the star image down to 2.4 mas rms at a frequency of about 0.02 Hz. However, the accuracy of the estimator is probably limited by a systematic error due to a misalignment of the Lyot stop with respect to the entrance pupil, estimated to be on the order of 4.5 mas. A method to reduce the amplitude of this bias down to 1 mas is proposed. The QACITS control loop has been successfully implemented and provides a robust method to center and stabilize the star image on the vortex mask. In addition, QACITS ensures a repeatable pointing quality and significantly improves the observing efficiency compared to manual operations. It is now routinely used for vortex coronagraph observations at Keck/NIRC2, providing contrast and angular resolution capabilities suited for exoplanet and disk imaging. [less ▲]Detailed reference viewed: 48 (11 ULiège) Blood Biomarkers in Idiopathic Pulmonary Fibrosis.GUIOT, Julien ; Moermans, Catherine; Henket, Monique et alin Lung (2017)PURPOSE: Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disease of unknown origin whose incidence has been increasing over the latest decade partly as a consequence of population ... [more ▼]PURPOSE: Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disease of unknown origin whose incidence has been increasing over the latest decade partly as a consequence of population ageing. New anti-fibrotic therapy including pirfenidone and nintedanib have now proven efficacy in slowing down the disease. Nevertheless, diagnosis and follow-up of IPF remain challenging. METHODS: This review examines the recent literature on potentially useful blood molecular and cellular biomarkers in IPF. Most of the proposed biomarkers belong to chemokines (IL-8, CCL18), proteases (MMP-1 and MMP-7), and growth factors (IGBPs) families. Circulating T cells and fibrocytes have also gained recent interest in that respect. Up to now, though several interesting candidates are profiling there has not been a single biomarker, which proved to be specific of the disease and predictive of the evolution (decline of pulmonary function test values, risk of acute exacerbation or mortality). CONCLUSION: Large scale multicentric studies are eagerly needed to confirm the utility of these biomarkers. [less ▲]Detailed reference viewed: 58 (8 ULiège) From Loose to Boxed Fragments and Back Again. Seriality and Archive in Chris Ware's ‘Building Stories’Crucifix, Benoît in Journal of Graphic Novels and Comics (2017)This article focuses on the dynamics of seriality, archive and collection in Chris Ware's graphic novel “Building Stories”. It argues that the dispersed serialization of “Building Stories” is key to ... [more ▼]This article focuses on the dynamics of seriality, archive and collection in Chris Ware's graphic novel “Building Stories”. It argues that the dispersed serialization of “Building Stories” is key to understand its box-of- comics format as well as its fragmented narrative structure. In a self-reflexive homage to the material history of comics, Ware's graphic novel indeed appears as an archive of its own serialization, foregrounding a process of collecting/dispersing fragments. [less ▲]Detailed reference viewed: 80 (38 ULiège) Les lésions musculaires des membres inférieurs : facteurs de risque et stratégies préventivesDelvaux, François ; Kaux, Jean-François ; Croisier, Jean-Louis in Science & Sports (2017)Detailed reference viewed: 107 (16 ULiège) OLFM4, KNG1 and Sec24C identified by proteomics and immunohistochemistry as potential markers of early colorectal cancer stagesQUESADA-CALVO, Florence ; MASSOT, Charlotte ; Bertrand, Virginie et alin Clinical Proteomics (2017), 24(9), Abstract Background: Despite recent advances in colorectal cancer (CRC) diagnosis and population screening programs, the identification of patients with preneoplastic lesions or with early CRC stages ... [more ▼]Abstract Background: Despite recent advances in colorectal cancer (CRC) diagnosis and population screening programs, the identification of patients with preneoplastic lesions or with early CRC stages remains challenging and is important for reducing CRC incidence and increasing patient’s survival. Methods: We analysed 76 colorectal tissue samples originated from early CRC stages, normal or inflamed mucosa by label-free proteomics. The characterisation of three selected biomarker candidates was performed by immunohisto‑ chemistry on an independent set of precancerous and cancerous lesions harbouring increasing CRC stages. Results: Out of 5258 proteins identified, we obtained 561 proteins with a significant differential distribution among groups of patients and controls. KNG1, OLFM4 and Sec24C distributions were validated in tissues and showed differ‑ ent expression levels especially in the two early CRC stages compared to normal and preneoplastic tissues. Conclusion: We highlighted three proteins that require further investigations to better characterise their role in early CRC carcinogenesis and their potential as early CRC markers. [less ▲]Detailed reference viewed: 37 (13 ULiège) Light, dark and the powerd that be: a hydroelectric project in ButemboGeenen, Kristien in Canadian Journal of African Studies (2017), 51(1), 43-54Despite its major importance in international trade, the city of Butembo in the North Kivu province of the Democratic Republic of Congo is deprived of such basic urban infrastructure as electricity ... [more ▼]Despite its major importance in international trade, the city of Butembo in the North Kivu province of the Democratic Republic of Congo is deprived of such basic urban infrastructure as electricity. Private and public actors have attempted to bring power to the city, but their efforts have remained fruitless. Analysis of these failed projects to electrify the city offers a glimpse of local power relations. Why, rather than cooperating, do various local power holders counteract each other? Will gaining credit for bringing electric power to the city in turn yield political power over its future? With a special focus on a hydroelectric dam that was built but never functioned, this article sheds light on the way in which the citizens of Butembo relate to different bodies of authority. I argue that the hydroelectric dam gradually became a tool in a larger political strategy [less ▲]Detailed reference viewed: 32 (2 ULiège) Iron minerals within speciﬁc microfossil morphospecies of the 1.88Ga Gunﬂint FormationLepot, kevin; Addad, Ahmed; Knoll, Andrew H et alin Nature Communications (2017), DOI: 10.1038/ncomms14890Detailed reference viewed: 44 (3 ULiège) Potential uses of pumped urban groundwater. A case study in Sant Adrià del Besòs (Spain)Jurado Elices, Anna ; Vázquez-Suñé; Pujades, Estanislao in Hydrogeology Journal (2017)Urban groundwater has been over-exploited during the past, mainly for industrial uses, and it now tends to be reduced or abandoned due to pollution and/or changes in land use. The use and the subsequent ... [more ▼]Urban groundwater has been over-exploited during the past, mainly for industrial uses, and it now tends to be reduced or abandoned due to pollution and/or changes in land use. The use and the subsequent disuse of groundwater resulted in rising water tables that damage underground structures (e.g., building basements and underground car parks and tunnels), leading to additional pumping in urban areas. This is the case of the underground parking lot of Sant Adrià del Besòs (NE Spain), where large amounts of urban groundwater are pumped to avoid seepage problems. The question that arises here is if this pumped groundwater can be used for other purposes (e.g., drinking water and urban irrigation) instead of wasting this valuable resource. To answer this question, it is necessary to quantify the groundwater recharge and to assess the evolution of ground-water quality in order to properly identify its potential uses. The limiting factor to define the uses of this resource is the groundwater quality because ammonium and some metals (iron and manganese) are present at high concentrations. Hence, further treatment would be needed to meet drinking water requirements. The pumped groundwater could also be used for supplying the ecological river flow and/or for mitigating seawater intrusion problems. Currently, only a small amount of this urban groundwater is used for cleaning public areas and watering public gardens. This situation highlighted the urgent need to manage this resource in a responsible and more efficient manner, especially in moments of high water demand such as drought periods. [less ▲]Detailed reference viewed: 40 (11 ULiège) Organocatalytic coupling of CO2 with oxetaneAlves, Margot ; Grignard, Bruno ; Boyaval, Amélie et alin ChemSusChem (2017), 10(6), 1128-1138The organocatalytic coupling of CO2 with oxetanes is investigated under solvent-free conditions. The influence of the main reaction parameters (type of organocatalytic system, pressure and temperature) on ... [more ▼]The organocatalytic coupling of CO2 with oxetanes is investigated under solvent-free conditions. The influence of the main reaction parameters (type of organocatalytic system, pressure and temperature) on the yield, the product formed and the selectivity of the reaction are discussed. An onium salt combined with a fluorinated alcohol promotes the efficient and selective organocatalytic synthesis of α,ω-hydroxyl oligocarbonates by coupling CO2 with oxetanes at 130 °C and at a CO2 pressure as low as 2 MPa. NMR characterizations were correlated with MALDI-ToF analyses for elucidating the structure of the oligomers. Online FTIR studies under pressure, NMR titrations and DFT calculations allowed an in-depth understanding of the reaction mechanism. Finally, CO2- based poly(carbonate-co-urethane)s were synthesized by step- growth polymerization of hydroxyl telechelic oligocarbonates with MDI. The organocatalytic system described in this paper constitutes an innovative sustainable route to the selective preparation of hydroxyl telechelic carbonates, of high interest for many applications, notably for the polyurethane business, especially for coatings or foams. [less ▲]Detailed reference viewed: 78 (28 ULiège) Organocatalytic coupling of CO2 with a propargylic alcohol: a comprehensive study of the reaction mechanism combining in- situ ATR-IR spectroscopy and DFT calculationsBoyaval, Amélie ; Méreau, Raphaël; Grignard, Bruno et alin ChemSusChem (2017), 10(6), 1241-1248The metal-free coupling of propargylic alcohols with carbon dioxide catalysed by guanidine derivatives was investigated in detail through the combination of online kinetic studies by in-situ ATR-IR ... [more ▼]The metal-free coupling of propargylic alcohols with carbon dioxide catalysed by guanidine derivatives was investigated in detail through the combination of online kinetic studies by in-situ ATR-IR spectroscopy and DFT calculations. Bicyclic guanidines, namely TBD and MTBD, are effective catalysts for the conversion of 2-methyl-3-butyn-2-ol to α-methylene cyclic carbonate and oxoalkyl acyclic carbonate under mild reaction conditions. The lower selectivity of TBD in comparison with MTBD towards the formation of α-methylene cyclic carbonate was elucidated from DFT calculations and is related to the bifunctional activity (base/H-bond donor) of TBD decreasing the Gibbs free energy of the reaction path for the formation of the acyclic carbonate. Introduction [less ▲]Detailed reference viewed: 55 (25 ULiège) Émeline Comby, Yannick Mosset, Stéphanie de Carrara (dir.), Corpus de textes : composer, mesurer, interpréterMathy, Adrien in Lectures (2017)Detailed reference viewed: 19 (0 ULiège) Ultimate strength of cylindrical shells with cutoutsEui Lee, Sang; Sahin; Rigo, Philippe et alin Ships and Offshore Structures (2017)Detailed reference viewed: 20 (3 ULiège) KNN-MDR: a learning approach for improving interactions mapping performances in genome wide association studiesAbo Al Chamlat, Sinan ; Farnir, Frédéric in BMC Bioinformatics (2017), 18Background Finding epistatic interactions in large association studies like genome-wide association studies (GWAS) with the nowadays-available large volume of genomic data is a challenging and largely ... [more ▼]Background Finding epistatic interactions in large association studies like genome-wide association studies (GWAS) with the nowadays-available large volume of genomic data is a challenging and largely unsolved issue. Few previous studies could handle genome-wide data due to the intractable difficulties met in searching a combinatorial explosive search space and statistically evaluating epistatic interactions given a limited number of samples. Our work is a contribution to this field. We propose a novel approach combining K-Nearest Neighbors (KNN) and Multi Dimensional Reduction (MDR) methods for detecting gene-gene interactions as a possible alternative to existing algorithms, e especially in situations where the number of involved determinants is high. After describing the approach, a comparison of our method (KNN-MDR) to a set of the other most performing methods (i.e., MDR, BOOST, BHIT, MegaSNPHunter and AntEpiSeeker) is carried on to detect interactions using simulated data as well as real genome-wide data. Results Experimental results on both simulated data and real genome-wide data show that KNN-MDR has interesting properties in terms of accuracy and power, and that, in many cases, it significantly outperforms its recent competitors. Conclusions The presented methodology (KNN-MDR) is valuable in the context of loci and interactions mapping and can be seen as an interesting addition to the arsenal used in complex traits analyses. [less ▲]Detailed reference viewed: 35 (24 ULiège) Simultaneous synthesis and chemical functionalization of emulsion-templated porous polymers using nitroxide-terminated macromolecular surfactantsMathieu, Kevin ; De Winter, Julien; Jérôme, Christine et alin Polymer Chemistry (2017), 8(11), 1850-1861The design of functional 3D macroporous monoliths has become a necessity for a wide range of applications. Traditional post-modification strategies of porous materials are efficient but often consist in ... [more ▼]The design of functional 3D macroporous monoliths has become a necessity for a wide range of applications. Traditional post-modification strategies of porous materials are efficient but often consist in tedious multi-steps processes. This work describes a straightforward macromolecular surfactant-assisted method for producing chemically functionalized macroporous polyHIPEs with interconnected structures. Accordingly, high internal phase emulsion-templated polymerizations were implemented in the presence of SG1-terminated amphiphilic copolymers prepared by nitroxide- mediated radical polymerization (NMP). The latter served as both stabilizers and functionalizing agents upon thermal activation of its terminal alkoxyamine and covalent anchoring of the released radical copolymer onto the walls of the scaffold. The effect of the polymerization temperature on the functionalization and openness of the final porous materials was explored. As a result, a range of open-cell styrene and acrylate-based polyHIPEs chemically grafted with PEO were obtained. Moreover, polyHIPEs were also decorated with alkyne-bearing PEO and subsequently modified via CuAAc click chemistry in order to demonstrate the potential of this macromolecular surfactants-assisted functionalization method. [less ▲]Detailed reference viewed: 28 (9 ULiège) Young general practitioners’ professional activities: a survey in the French-speaking part of BelgiumLenoir, Anne-Laure ; Richelle, Lou; Ketterer, Frédéric et alin Acta Clinica Belgica (2017)Detailed reference viewed: 28 (10 ULiège) Influence of granular fraction and origin of recycled concrete aggregates on their propertiesZhao, Zengfeng ; Courard, Luc ; Michel, Frédéric et alin European Journal of Environmental and Civil Engineering (2017)Large quantities of construction and demolition wastes are produced each year. In order to make good use of recycled concrete aggregates (RCA) in concrete, it is very important to study the influence of ... [more ▼]Large quantities of construction and demolition wastes are produced each year. In order to make good use of recycled concrete aggregates (RCA) in concrete, it is very important to study the influence of the granular fraction and the origin of RCA on their properties. In this study, RCA from industrial produced blocks (RCA_Blocks) and slabs (RCA_Slabs) were crushed and then separated into four granular fractions (0/2, 2/6.3, 6.3/14, 14/20 mm). Each granular fraction of RCA was physically characterised. Real RCA from recycling plant were also used for comparison. The results showed that recycled sands offered significantly higher cement paste content (higher bound water content) than coarse recycled aggregates. The fine RCA had therefore a higher water absorption coefficient compared to coarser fractions of RCA. The water absorption of finer fraction of RCA could be extrapolated precisely from the relationship between water absorption and cement paste content (or bound water content) of three coarse fractions of RCA. The values of hardened cement paste content obtained for the RCA_Blocks were lower than those measured on the RCA_Slabs, which was due to a smaller amount of initial cement paste content in blocks. The results showed that RCA_Slabs were more angular than RCA_Blocks. [less ▲]Detailed reference viewed: 29 (5 ULiège) Water Vapor Permeability of Edible Films Based on Improved Cassava (Manihot esculenta Crantz) Native StarchesAdjouman, Yao Désiré; Nindjin, Charlemagne; Tetchi, F.Achille et alin Journal of Food Processing & Technology (2017), 8Starch is used in the production of edible biodegradable packaging as an attractive alternative to synthetic polymers because it is a natural biopolymer of low cost and high availability. Many studies ... [more ▼]Starch is used in the production of edible biodegradable packaging as an attractive alternative to synthetic polymers because it is a natural biopolymer of low cost and high availability. Many studies have been carried out on films based on cassava starch and the results show that these have good flexibility and low water vapor permeability. This present research was conducted to analyse the effect of glycerol, peanut oil and soybean lecithin on the water vapor permeability (WVP) of edible films based on improved cassava (Manihot esculenta Crantz) native starches from Côte d’Ivoire. The films were prepared using 4 g cassava starch, 25% and 30% glycerol (w/w), 5% and 10% peanut oil (w/w) and 0% to 5% soybean lecithin (w/w oil) in Petri dishes. The WVP of the films was determined at 25°C and 75% relative humidity. The moisture content of the films was determined in an oven at 105°C and the film thickness was determined manually using a micrometer. The resulting films were homogeneous, transparent and crack-free. WVP, moisture content and thickness of the films increased with increasing glycerol concentration. Increasing the concentrations of the peanut oil and soybean lecithin decreased the thickness and increased the moisture content of the films. The combination of glycerol and peanut oil increased the WVP of the films, whereas addition of soybean lecithin had no effect. The lowest WVP values were obtained using 25% glycerol, 5% peanut oil and 5% soybean lecithin. Starch obtained from improved cassava varieties cultivated in Côte d’Ivoire can be a potential ingredient in the production of food packaging. [less ▲]Detailed reference viewed: 47 (1 ULiège) RNAi inhibition of feruloyl CoA 6'-hydroxylase reduces scopoletin biosynthesis and post-harvest physiological deterioration in cassava (Manihot esculenta Crantz) storage roots.Liu, Shi; Zainuddin, Ima M.; Vanderschuren, Hervé et alin Plant Molecular Biology (2017)Cassava (Manihot esculenta Crantz) is a major world crop, whose storage roots provide food for over 800 million throughout the humid tropics. Despite many advantages as a crop, the development of cassava ... [more ▼]Cassava (Manihot esculenta Crantz) is a major world crop, whose storage roots provide food for over 800 million throughout the humid tropics. Despite many advantages as a crop, the development of cassava is seriously constrained by the rapid post-harvest physiological deterioration (PPD) of its roots that occurs within 24-72 h of harvest, rendering the roots unpalatable and unmarketable. PPD limits cassava's marketing possibilities in countries that are undergoing increased development and urbanisation due to growing distances between farms and consumers. The inevitable wounding of the roots caused by harvesting triggers an oxidative burst that spreads throughout the cassava root, together with the accumulation of secondary metabolites including phenolic compounds, of which the coumarin scopoletin (7-hydroxy-6-methoxy-2H-1-benzopyran-2-one) is the most abundant. Scopoletin oxidation yields a blue-black colour, which suggests its involvement in the discoloration observed during PPD. Feruloyl CoA 6'-hydroxylase is a controlling enzyme in the biosynthesis of scopoletin. The cassava genome contains a seven membered family of feruloyl CoA 6'-hydroxylase genes, four of which are expressed in the storage root and, of these, three were capable of functionally complementing Arabidopsis T-DNA insertion mutants in this gene. A RNA interference construct, designed to a highly conserved region of these genes, was used to transform cassava, where it significantly reduced feruloyl CoA 6'-hydroxylase gene expression, scopoletin accumulation and PPD symptom development. Collectively, our results provide evidence that scopoletin plays a major functional role in the development of PPD symptoms, rather than merely paralleling symptom development in the cassava storage root. [less ▲]Detailed reference viewed: 28 (1 ULiège) Development of nuclear SNP markers for genetic tracking of Iroko, Milicia excelsa and Milicia regiaBlanc-Jolivet, Céline; Kersten, Birgit; Daïnou, Kasso et alin Conservation Genetics Resources (2017)Iroko, Milicia excelsa, is an economically important tropical hardwood species widely distributed in tropical Africa, from Ivory Coast in Western Africa to Tanzania in Eastern Africa. The species occurs ... [more ▼]Iroko, Milicia excelsa, is an economically important tropical hardwood species widely distributed in tropical Africa, from Ivory Coast in Western Africa to Tanzania in Eastern Africa. The species occurs at low densities in contrasting habitats such as rainforest and woodlands. Former studies using chloroplast and nuclear sequences, as well as nSSRs, revealed a strong diﬀerentiation within the species among West and Central African populations and the presence of three genetic groups in Central Africa (Daïnou et al. 2010, 2014). The genus Milicia also includes another species, M. regia, co-occurring with M. excelsa in West Africa. Both species can be identified genetically and morphologically (Daïnou et al. 2014), but identification is difficult in the field. Although the spatial genetic structure of the species is well described, it is mostly based on nSSRs. Despite their lower diversity, SNP markers provide several advantages including the uncomplicated standardization of data among laboratories and the easy, rapid and low-cost development of markers for large sets of loci. These features make SNPs the ideal markers for setting up genetic reference data for timber tracking (Blanc-Jolivet and Liesebach 2015; Degen et al. 2017; Jardine et al. 2016; Pakull et al. 2016). In this paper, we describe the development of a new set of nuclear SNPs on M. excelsa meant to be used for genetic timber tracking. [less ▲]Detailed reference viewed: 71 (9 ULiège) Statistics of localized phase slips in tunable width planar point contactsBaumans, Xavier ; Zharinov, Vyacheslav; Raymenants, Eline et alin Scientific Reports (2017), 7The main dissipation mechanism in superconducting nanowires arises from phase slips. Thus far, most of the studies focus on long nanowires where coexisting events appear randomly along the nanowire. In ... [more ▼]The main dissipation mechanism in superconducting nanowires arises from phase slips. Thus far, most of the studies focus on long nanowires where coexisting events appear randomly along the nanowire. In the present work we investigate highly confined phase slips at the contact point of two superconducting leads. Profiting from the high current crowding at this spot, we are able to shrink in-situ the nanoconstriction. This procedure allows us to investigate, in the very same sample, thermally activated phase slips and the probability density function of the switching current I sw needed to trigger an avalanche of events. Furthermore, for an applied current larger than I sw , we unveil the existence of two distinct thermal regimes. One corresponding to efficient heat removal where the constriction and bath temperatures remain close to each other, and another one in which the constriction temperature can be substantially larger than the bath temperature leading to the formation of a hot spot. Considering that the switching current distribution depends on the exact thermal properties of the sample, the identification of different thermal regimes is of utmost importance for properly interpreting the dissipation mechanisms in narrow point contacts. [less ▲]Detailed reference viewed: 79 (25 ULiège) Modelling of organic Rankine cycle power systems in off-design conditions: an experimentally-validated comparative studyDickes, Rémi ; Dumont, Olivier ; Daccord, Rémi et alin Energy (2017), 123Because of environmental issues and the depletion of fossil fuels, the world energy sector is undergoing many changes toward increased sustainability. Among the many fields of research and development ... [more ▼]Because of environmental issues and the depletion of fossil fuels, the world energy sector is undergoing many changes toward increased sustainability. Among the many fields of research and development, power generation from low-grade heat sources is gaining interest and the organic Rankine cycle (ORC) is seen as one of the most promising technologies for such applications. In this paper, it is proposed to perform an experimentally-validated comparison of different modelling methods for the off-design simulation of ORC-based power systems. To this end, three types of modelling paradigms (namely a constant-efficiency method, a polynomial-based method and a semi-empirical method) are compared both in terms of their fitting and extrapolation capabilities. Post-processed measurements gathered on two experimental ORC facilities are used as reference for the models calibration and evaluation. The study is first applied at a component level (i.e. each component is analysed individually) and then extended to the characterization of the entire organic Rankine cycle power systems. Benefits and limi- tations of each modelling method are discussed. The results show that semi-empirical models are the most reliable for simulating the off-design working conditions of ORC systems, while constant-efficiency and polynomial-based models are both demonstrating lack of accuracy and/or robustness. [less ▲]Detailed reference viewed: 132 (22 ULiège) Underground pumped storage hydropower plants using open pit mines: How do groundwater exchanges influence the efficiency?Pujades, Estanislao ; Orban, Philippe ; Bodeux, Sarah et alin Applied Energy (2017), 190Underground Pumped Storage Hydropower (UPSH) is a potential alternative to manage electricity production in flat regions. UPSH plants will interact with the surrounding porous medium through exchanges of ... [more ▼]Underground Pumped Storage Hydropower (UPSH) is a potential alternative to manage electricity production in flat regions. UPSH plants will interact with the surrounding porous medium through exchanges of groundwater. These exchanges may impact the surrounding aquifers, but they may also influence the efficiency of the pumps and turbines because affecting the head difference between the reservoirs. Despite the relevance for an accurate efficiency assessment, the influence of the groundwater exchanges has not been previously addressed. A numerical study of a synthetic case is presented to highlight the importance of considering the groundwater exchanges with the surrounding porous medium. The general methodology is designed in order to be further applied in the decision making of future UPSH plants introducing each case specific complexity. The underground reservoir of a hypothetical UPSH plant, which consists in an open pit mine, is considered and modelled together with the surrounding porous medium. Several scenarios with different characteristics are simulated and their results are compared in terms of (1) head difference between the upper and lower reservoirs and (2) efficiency by considering the theoretical performance curves of a pump and a turbine. The results show that the efficiency is improved when the groundwater exchanges increase. Thus, the highest efficiencies will be reached when (1) the underground reservoir is located in a transmissive porous medium and (2) the walls of the open pit mine do not constrain the groundwater exchanges (they are not waterproofed). However, a compromise must be found because the characteristics that increase the efficiency also increase the environmental impacts. Meaningful and reliable results are computed in relation to the characteristics of the intermittent and expected stops of UPSH plants. The frequency of pumping and injection must be considered to properly configure the pumps and turbines of future UPSH plants. If not, pumps and turbines could operate far from their best efficiency conditions. [less ▲]Detailed reference viewed: 33 (4 ULiège) Cynicism ex machina: The emotionality of reporting the ‘refugee crisis’ and Paris terrorist attacks in Czech Television.Kotisova, Johana in European Journal of Communication (2017)Detailed reference viewed: 10 (2 ULiège) Development and validation of a fast SFC method for the analysis of flavonoids in plant extractsHuang, Yang ; Feng, Ying; Tang, Guangyun et alin Journal of Pharmaceutical and Biomedical Analysis (2017), 140Detailed reference viewed: 14 (1 ULiège) MacroH2A histone variants maintain nuclear organization and heterochromatin architecture.Douet, Julien; Corujo, David; Malinverni, Roberto et alin Journal of Cell Science (2017)Genetic loss-of-function studies in development, cancer and somatic cell reprogramming have suggested that the group of macroH2A histone variants might function through stabilizing the differentiated ... [more ▼]Genetic loss-of-function studies in development, cancer and somatic cell reprogramming have suggested that the group of macroH2A histone variants might function through stabilizing the differentiated state by a yet unknown mechanism. Here, we present results demonstrating that macroH2A variants have a major function in maintaining nuclear organization and heterochromatin architecture. Specifically, we find that a substantial amount of macroH2A is associated with heterochromatic repeat sequences. We further identify macroH2A on sites of interstitial heterochromatin decorated by H3K9me3. Loss of macroH2A leads to major defects in nuclear organization including reduced nuclear circularity, disruption of nucleoli and a global loss of dense heterochromatin. Domains formed by repeat sequences when depleted of macroH2A are disorganized, expanded and fragmented and mildly re-expressed. On the molecular level we find that macroH2A is required for the interaction of repeat sequences with the nucleostructural protein Lamin B1. Taken together our results argue that a major function of macroH2A histone variants is to link nucleosome composition to higher order chromatin architecture. [less ▲]Detailed reference viewed: 21 (6 ULiège) Structure of Herbig AeBe disks at the milliarcsecond scale. A statistical survey in the H band using PIONIER-VLTILazareff, B.; Berger, J.-P.; Kluska, J. et alin Astronomy and Astrophysics (2017), 599Context. It is now generally accepted that the near-infrared excess of Herbig AeBe stars originates in the dust of a circumstellar disk. Aims. The aims of this article are to infer the radial and vertical ... [more ▼]Context. It is now generally accepted that the near-infrared excess of Herbig AeBe stars originates in the dust of a circumstellar disk. Aims. The aims of this article are to infer the radial and vertical structure of these disks at scales of order one au, and the properties of the dust grains. Methods. The program objects (51 in total) were observed with the H-band (1.6micron) PIONIER/VLTI interferometer. The largest baselines allowed us to resolve (at least partially) structures of a few tenths of an au at typical distances of a few hundred parsecs. Dedicated UBVRIJHK photometric measurements were also obtained. Spectral and 2D geometrical parameters are extracted via fits of a few simple models: ellipsoids and broadened rings with azimuthal modulation. Model bias is mitigated by parallel fits of physical disk models. Sample statistics were evaluated against similar statistics for the physical disk models to infer properties of the sample objects as a group. Results. We find that dust at the inner rim of the disk has a sublimation temperature Tsub~1800K. A ring morphology is confirmed for approximately half the resolved objects; these rings are wide delta_r>=0.5. A wide ring favors a rim that, on the star-facing side, looks more like a knife edge than a doughnut. The data are also compatible with a the combination of a narrow ring and an inner disk of unspecified nature inside the dust sublimation radius. The disk inner part has a thickness z/r~0.2, flaring to z/r~0.5 in the outer part. We confirm the known luminosity-radius relation; a simple physical model is consistent with both the mean luminosity-radius relation and the ring relative width; however, a significant spread around the mean relation is present. In some of the objects we find a halo component, fully resolved at the shortest interferometer spacing, that is related to the HAeBe class. [less ▲]Detailed reference viewed: 22 (5 ULiège) Strategic Points in AquaponicsJunge, Ranka; König, Bettina; Villarroel, Morris et alin Water (2017), 9(182), Detailed reference viewed: 45 (3 ULiège) Behavior of digital sequences through exotic numeration systemsLeroy, Julien ; Rigo, Michel ; Stipulanti, Manon in Electronic Journal of Combinatorics (2017), 24(1), 14436Many digital functions studied in the literature, e.g., the summatory function of the base-k sum-of-digits function, have a behavior showing some periodic fluctuation. Such functions are usually studied ... [more ▼]Many digital functions studied in the literature, e.g., the summatory function of the base-k sum-of-digits function, have a behavior showing some periodic fluctuation. Such functions are usually studied using techniques from analytic number theory or linear algebra. In this paper we develop a method based on exotic numeration systems and we apply it on two examples motivated by the study of generalized Pascal triangles and binomial coefficients of words. [less ▲]Detailed reference viewed: 67 (21 ULiège) Bioavailability enhancement of itraconazole-based solid dispersions produced by hot melt extrusion in the framework of the Three Rs ruleThiry, Justine ; Kok, Miranda ; Collard, Laurence et alin European Journal of Pharmaceutical Sciences (2017), 99Solid dispersion formulations made of itraconazole (ITZ) and Soluplus® (polyethylene glycol, polyvinyl acetate and polyvinylcaprolactame-based graft copolymer abbreviated SOL) were produced using hot melt ... [more ▼]Solid dispersion formulations made of itraconazole (ITZ) and Soluplus® (polyethylene glycol, polyvinyl acetate and polyvinylcaprolactame-based graft copolymer abbreviated SOL) were produced using hot melt extrusion. Since ITZ possesses a water solubility of less than 1 ng/mL, the aim of this work was to enhance the aqueous solubility of ITZ, and thereby improve its bioavailability. The three formulations consisted of a simple SOL/ITZ amorphous solid dispersion (ASD), an optimized SOL/ITZ/AcDiSol® (super-disintegrant) ASD and an equimolar inclusion complex of ITZ in hydroxypropyl-β-cyclodextrin (substitution degree = 0.63, CD) with SOL. The three formulations were compared in vitro and in vivo to the marketed product Sporanox®. The in vitro enhancement of dissolution rate was evaluated using a biphasic dissolution test. In vitro dissolution results showed that all three formulations had a higher percentage of ITZ released than Sporanox® with the following ranking: SOL/ITZ/CD > SOL/ITZ/AcDiSol® > SOL/ITZ > Sporanox®. The bioavailability of these four formulations was evaluated in rats. The bioanalytical method was optimized so that only 10 μL of blood was withdrawn from the rats using specific volumetric absorptive microsampling devices. This enabled to keep the same rats during the whole study, which was in accordance with the Three Rs rules (reduction, refinement and replacement). Furthermore, this technique allowed the suppression of inter-individual variability. Higher Cmax and AUC were obtained after the administration of all three formulations compared to the levels after the use of Sporanox® as follows: SOL/ITZ/AcDiSol® > SOL/ITZ/CD > SOL/ITZ > Sporanox®. The inversion in the ranking between SOL/ITZ/CD and SOL/ITZ/AcDiSol® made impossible the establishment of an in vitro–vivo correlation. Indeed, very different release rates were obtained in vitro and in vivo for the two optimized formulations. These results suggest that ITZ would be protected inside the core of the SOL micelles even during the absorption step at the intestine, while some agents present in the intestinal fluids could displace ITZ from the hydrophobic cavity of CD by competition. [less ▲]Detailed reference viewed: 31 (19 ULiège) Perspectives for observing hot massive stars with XMM-Newton in the years 2017-2027Rauw, Grégor in Astronomische Nachrichten (2017), 338XMM-Newton has deeply changed our picture of X-ray emission of hot, massive stars. High-resolution X-ray spectroscopy as well as monitoring of these objects helped us gain a deeper insight into the ... [more ▼]XMM-Newton has deeply changed our picture of X-ray emission of hot, massive stars. High-resolution X-ray spectroscopy as well as monitoring of these objects helped us gain a deeper insight into the physics of single massive stars with or without magnetic fields, as well as of massive binary systems, where the stellar winds of both stars interact. These observations also revealed a number of previously unexpected features that challenge our understanding of the dynamics of the stellar winds of massive stars. I briefly summarize the results obtained over the past 15 years and highlight the perspectives for the next decade. It is anticipated that coordinated (X-ray and optical or UV) monitoring and time-critical observations of either single or binary massive stars will become the most important topics in this field over the coming years. Synergies with existing or forthcoming X-ray observatories (NuSTAR, Swift, eROSITA) will also play a major role and will further enhance the importance of XMM-Newton in our quest for understanding the physics of hot, massive stars. [less ▲]Detailed reference viewed: 13 (1 ULiège) Adaptive PSF fitting - a highly performing photometric method and light curves of the GLS H1413+117: time delays and micro-lensing effectsAkhunov, Talat ; Wertz, O.; Elyiv, A. et alin Monthly Notices of the Royal Astronomical Society (2017), 465We present new photometric observations of H1413+117 acquired during seasons between 2001 and 2008 in order to estimate the time delays between the lensed quasar images and to characterize at best the on ... [more ▼]We present new photometric observations of H1413+117 acquired during seasons between 2001 and 2008 in order to estimate the time delays between the lensed quasar images and to characterize at best the on-going micro-lensing events. We propose a highly performing photometric method called the adaptive point spread function fitting and have successfully tested this method on a large number of simulated frames. This has enabled us to estimate the photometric error bars affecting our observational results. We analysed the V- and R-band light curves and V-R colour variations of the A-D components which show short- and long-term brightness variations correlated with colour variations. Using the χ[SUP]2[/SUP] and dispersion methods, we estimated the time delays on the basis of the R-band light curves over the seasons between 2003 and 2006. We have derived the new values: Δt[SUB]AB[/SUB] = -17.4 ± 2.1, Δt[SUB]AC[/SUB] = -18.9 ± 2.8 and Δt[SUB]AD[/SUB] = 28.8 ± 0.7 d using the χ[SUP]2[/SUP] method (B and C are leading, D is trailing) with 1σ confidence intervals. We also used available observational constraints (resp. the lensed image positions, the flux ratios in mid-IR and two sets of time delays derived in the present work) to update the lens redshift estimation. We obtained z_l = 1.95^{+0.06}_{-0.10} which is in good agreement with previous estimations. We propose to characterize two kinds of micro-lensing events: micro-lensing for the A, B, C components corresponds to typical variations of ∼10[SUP]-4[/SUP] mag d[SUP]-1[/SUP] during all the seasons, while the D component shows an unusually strong micro-lensing effect with variations of up to ∼10[SUP]-3[/SUP] mag d[SUP]-1[/SUP] during 2004 and 2005. [less ▲]Detailed reference viewed: 18 (0 ULiège) Lacustrine clay mineral assemblages as a proxy for land-use and climate changes over the last 4 kyr: The Amik Lake case study, Southern TurkeyEl Ouahabi, Meriam ; Hubert, Aurelia ; Fagel, Nathalie in Quaternary International (2017), 1/15Lake sediments are sensitive to landscape changes and most of these changes seem to be modulated by land-use (anthropogenic factors) coupled to palaeoenvironmental/palaeoclimatic changes. In its detrital ... [more ▼]Lake sediments are sensitive to landscape changes and most of these changes seem to be modulated by land-use (anthropogenic factors) coupled to palaeoenvironmental/palaeoclimatic changes. In its detrital fraction, the lacustrine sediments record the history of soil erosion within its catchment via the inputs of clays and others detrital products. Within a Mediterranean context, the study investigates the upper sediments infilling the central part of the Amik basin in southern Turkey. This tectonic basin was occupied and exploited by modern human at least since 6000-7000 BC. We focus on the clay mineralogy (x-ray diffraction on oriented aggregates) and magnetic susceptibility measurements (Bartington) of the sedimentary record in the area over the last 4000 years, to assess environmental changes in relation with the different land uses and/or weathering during the successive Bronze, Iron, Roman, Islamic/Ottoman and Modern civilizations. The clay fraction of Amik Lake sediments comprises smectite, kaolinite, illite, chlorite and chlorite/smectite mixed layers that are the inherited clay phases. A relative change in abundance and crystallinity and chemistry of illite attests that environmental conditions evolved in the Amik Plain from the Bronze to Modern Age in relation with climates and/or land-use changes. The history of the Amik Lake reveals different soil erosion episode. The most intense erosion phase occurred during the Bronze/Iron Ages as indicated by the clay and magnetic susceptibility proxies. The Roman period was an exceptional period with soil erosion products arriving from the watershed, probably due the water channelization. A reduction of soil erosion occurred during the post Roman period until nowadays. Significant pedogenesis transformations are evidenced, especially during the Islamic/Ottoman periods suggesting intense chemical weathering conditions related to climate change. [less ▲]Detailed reference viewed: 67 (25 ULiège) The XXL survey: First results and futurePierre, M.; Adami, C.; Birkinshaw, M. et alin Astronomische Nachrichten (2017), 338The XXL survey currently covers two 25 sq. deg. patches with XMM observations of ~10ks. We summarise the scientific results associated with the first release of the XXL data set, that occurred mid 2016 ... [more ▼]The XXL survey currently covers two 25 sq. deg. patches with XMM observations of ~10ks. We summarise the scientific results associated with the first release of the XXL data set, that occurred mid 2016. We review several arguments for increasing the survey depth to 40 ks during the next decade of XMM operations. X-ray (z<2) cluster, (z<4) AGN and cosmic background survey science will then benefit from an extraordinary data reservoir. This, combined with deep multi-$\lambda$ observations, will lead to solid standalone cosmological constraints and provide a wealth of information on the formation and evolution of AGN, clusters and the X-ray background. In particular, it will offer a unique opportunity to pinpoint the z>1 cluster density. It will eventually constitute a reference study and an ideal calibration field for the upcoming eROSITA and Euclid missions. [less ▲]Detailed reference viewed: 19 (1 ULiège) H0LiCOW - IV. Lens mass model of HE 0435-1223 and blind measurement of its time-delay distance for cosmologyWong, Kenneth C.; Suyu, Sherry H.; Auger, Matthew W. et alin Monthly Notices of the Royal Astronomical Society (2017), 465Strong gravitational lenses with measured time delays between the multiple images allow a direct measurement of the time-delay distance to the lens, and thus a measure of cosmological parameters ... [more ▼]Strong gravitational lenses with measured time delays between the multiple images allow a direct measurement of the time-delay distance to the lens, and thus a measure of cosmological parameters, particularly the Hubble constant, H[SUB]0[/SUB]. We present a blind lens model analysis of the quadruply imaged quasar lens HE 0435-1223 using deep Hubble Space Telescope imaging, updated time-delay measurements from the COSmological MOnitoring of GRAvItational Lenses (COSMOGRAIL), a measurement of the velocity dispersion of the lens galaxy based on Keck data, and a characterization of the mass distribution along the line of sight. HE 0435-1223 is the third lens analysed as a part of the H[SUB]0[/SUB] Lenses in COSMOGRAIL's Wellspring (H0LiCOW) project. We account for various sources of systematic uncertainty, including the detailed treatment of nearby perturbers, the parametrization of the galaxy light and mass profile, and the regions used for lens modelling. We constrain the effective time-delay distance to be D_{Δ t}= 2612_{-191}^{+208} Mpc, a precision of 7.6 per cent. From HE 0435-1223 alone, we infer a Hubble constant of H[SUB]0[/SUB] = 73.1_{-6.0}^{+5.7} km s^{-1 Mpc^{-1}} assuming a flat ΛCDM cosmology. The cosmographic inference based on the three lenses analysed by H0LiCOW to date is presented in a companion paper (H0LiCOW Paper V). [less ▲]Detailed reference viewed: 12 (0 ULiège) Evolutionary status of the Of?p star HD 148937 and of its surrounding nebula NGC 6164/5Mahy, Laurent ; Hutsemekers, Damien ; Nazé, Yaël et alin Astronomy and Astrophysics (2017), 599(A61), 17