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See detailEmergency support of transmission voltages by active distribution networks: a non-intrusive scheme
Pabon Ospina, Luis David; Van Cutsem, Thierry ULiege

in IEEE Transactions on Power Systems (in press)

Non-negligible amounts of Distributed Generating Units (DGUs) are already connected to power systems, predominantly to medium- and low-voltage networks. The interaction between distribution and ... [more ▼]

Non-negligible amounts of Distributed Generating Units (DGUs) are already connected to power systems, predominantly to medium- and low-voltage networks. The interaction between distribution and transmission systems is gaining the attention of system operators. Given the high controlability of DGUs, the active distribution networks can potentially support the transmission system during emergency situations. Previously proposed voltage emergency controls involving distribution network assets focused on preserving the transmission system integrity, even if it implies affecting the distribution system operation (intrusive schemes). More attention needs to be devoted to supporting transmission voltages, while preserving the distribution network operation (non-intrusive schemes). This paper introduces a new adaptive and non-intrusive voltage emergency control scheme based on the synchronization of DGUs and the load tap changer of the corresponding distribution transformer. The conclusions are derived from time-domain simulations using an extended version of the IEEE Nordic test system for voltage stability assessment. [less ▲]

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See detailLessons from the Belgian experience with regulatory control during the COVID-19 pandemic for the implementation of the European IVD regulation 2017/746.
Vermeersch, Pieter; Cotton, Frédéric; De Smet, Dieter et al

in Acta Clinica Belgica (in press)

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See detailUn regard post-coloniliste de la médiatisation européenne à l'heure des Femen en Tunisie
Luceno Moreno, Marta ULiege

in Open Library of Humanities (in press)

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See detailPeter Watkins et les apories de la lutte médiatique. Enjeux et limites de la critique de la monoforme dans 'La Commune (Paris, 1871)'
Hamers, Jérémy ULiege

in COnTEXTES: Revue de Sociologie de la Littérature (in press), 30

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See detailStatistics and linguistics: can we tell something more about Pliny the Elder?
Fantoli, Margherita ULiege

in Classics@ (in press)

Présentation des outils et des méthodes L.A.S.L.A. et discussion des premiers résultats des tests statistiques sur le deuxième livre de la Naturalis Historia de Pline l'Ancien.

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See detailRisk factors for a severe form of COVID-19 after allogeneic haematopoietic stem cell transplantation : a SFGM-TC multicentre cohort study
Xhaard, A.; Xhaard, C.; d'Aveni, M. et al

in British Journal of Haematology (in press)

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See detailGreen composites based on thermoplastic starches and various natural plant fibers: Impacting parameters of the mechanical properties using machine-learning
Morin, Sophie ULiege; Dumoulin, Lionel ULiege; Delahaye, Louise ULiege et al

in Polymer Composites (in press)

Multivariate analyses on formulation and mechanical behavior of nonwoven and nonoriented natural fibers reinforced thermoplastic starch (TPS) composites were performed. Glycerol and water were considered ... [more ▼]

Multivariate analyses on formulation and mechanical behavior of nonwoven and nonoriented natural fibers reinforced thermoplastic starch (TPS) composites were performed. Glycerol and water were considered as TPS plasticizers. Fibers composition (i.e., cellulose, hemicellulose, lignin), fibers morphology (fibers length), starch composition (i.e., amylose/amylopectin ratio) as well as the processing conditions (i.e., temperature, rotor speed, relative humidity during aging) were evaluated for their ability to affect the elastic modulus, tensile strength, and elongation at break of the final materials. Multivariate linear regressions were computed to unveil the importance of each variable on the mechanical behavior. Fibers composition impacted the most the models: cellulose maximization improved the elastic modulus and tensile strength while lignin reduced the elastic modulus and hemicellulose decreased the tensile strength. TPS plasticizers, temperature, and rotor speed of the process were negatively impacting the elastic modulus but in a lesser extent than the fiber composition. Within the range of the created database, the selected variables and attributed coefficients were permitted to explain the variability. The produced models revealed that complex and yet uninvestigated interactions are to be considered within TPS-based biocomposites. Therefore, this work discusses and suggests a “must-have” list of variables for comparable analyses of new TPS-based biocomposites using natural fibers as reinforcement. [less ▲]

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See detailHolomorphic cohomological convolution and Hadamard product
Dubussy, Christophe ULiege; Schneiders, Jean-Pierre ULiege

in Publications of the Research Institute for Mathematical Sciences (in press)

In this article, we explain the link between Pohlen's extended Hadamard product and the holomorphic cohomological convolution on C^*. For this purpose, we introduce a generalized Hadamard product, which ... [more ▼]

In this article, we explain the link between Pohlen's extended Hadamard product and the holomorphic cohomological convolution on C^*. For this purpose, we introduce a generalized Hadamard product, which is defined even if the holomorphic functions do not vanish at infinity, as well as a notion of strongly convolvable sets. [less ▲]

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See detailAberrations chromatiques : de l’émulsion au pixel
Thonon, Jonathan ULiege

in Cahiers Louis Lumière (in press)

Dans l’une de ses conversations avec Joachim Gasquet sur le sens de sa peinture (et de la peinture en général), Cézanne aborde de front la conception qu’il se fait de la couleur, dans son rapport à la ... [more ▼]

Dans l’une de ses conversations avec Joachim Gasquet sur le sens de sa peinture (et de la peinture en général), Cézanne aborde de front la conception qu’il se fait de la couleur, dans son rapport à la profondeur picturale et de son articulation à la surface : « La nature n'est pas en surface ; elle est en profondeur. Les couleurs sont l'expression, à cette surface, de cette profondeur. Elles montent des racines du monde ». Cet « organisme de couleurs » que constitue le monde est transcrit dans la peinture de Cézanne par une dynamique symbiotique de la couleur et du dessin, de la ligne et du pan. La couleur restitue, par sa masse, son surgissement, son homogénéité, presque sa viscosité, la véritable chaire perceptive du monde ; une vision qui tient à distance la perspective géométrique, photographique, cinématographique fondée sur la transparence et qui repose, comme le signale Merleau-Ponty, sur la « réversibilité des dimensions » (surface-profondeur) et l’entrelacement des choses. C’est cette épaisseur du visible rendu par la couleur que l’économie de l’image numérique nous permet de redécouvrir, moins dans le registre de la « tactilité » de l’image et la picturalité du pixel, que par l’intégration, entre le support et l’image (parfois indiscernables dans le régime optique), d’un « corps » algorithmique qui règle l’actualisation du visible. Certains défauts techniques du dispositif numérique, aujourd’hui élevés au rang de pratique artistique, permettent de révéler cette matrice qui utilise alors la couleur et la coulure comme mode de visibilité. C’est le cas du Datamoshing, technique de composition numérique qui revisite tout en la radicalisant la pratique de l’incrustation vidéo. Basée sur la perturbation volontaire d’éléments de la matrice, cette technique transforme les couleurs en une forme malléable et fluide révélant ainsi leur double nature spatiale : elles sont à la fois dans l’espace de l’image et l’espace de l’image lui-même. Ces expériences de défigurations d’images s’inscrivent dans le registre des « aberrations chromatiques » dont nous proposons ici une rapide généalogie avant d’interroger la couleur digitale dans ses spécificités. [less ▲]

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See detailReview of [Guillem de Torroella, La faula, éd. Anna Maria Compagna, trad. Jean-Marie Barberà, Paris, Classiques Garnier, 2020]
Morato, Nicola ULiege

in Moyen Age: Revue d'Histoire et de Philologie (in press)

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See detailL’intreccio del Tristan en prose e altri appunti
Morato, Nicola ULiege

in Stilistica e Metrica Italiana (in press)

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See detailEarly Management of Acute Unilateral Vocal Fold Paralysis: Update of the Literature
Marques, Joana; Marronnier, Adrien; Crampon, Frederic et al

in Journal of Voice (in press)

Background. Unilateral vocal fold paralysis (UVFP) often leads to significant morbidity that may include dysphonia, swallowing problems and aspiration. The best timing for medialization procedures is ... [more ▼]

Background. Unilateral vocal fold paralysis (UVFP) often leads to significant morbidity that may include dysphonia, swallowing problems and aspiration. The best timing for medialization procedures is still controversial. Published data suggest that early intracordal injection positively affects long-term outcomes. Objectives. To critically review current literature in order to determine if early treatment of acute UVFP influences clinical outcomes of the patients. Type of Review. Nonsystematic literature review. Methods. A literature review was performed, using the Pubmed database. All relevant articles published in English addressing the effect of early treatment in acute unilateral focal fold paralysis were analyzed. Twenty-six articles were included due to their scientific interest. Results. Published literature suggests that early intracordal injection in patients with UVFP reduces pulmonary infections, hospital length of stay and improves voice parameters. Also, patients who receive early intracordal injection seem to be less likely to undergo subsequent medialization thyroplasty. Conclusions. Early intracordal injection should be offered to patients with newly diagnosed UVFP since it promotes a satisfactory position of the vocal fold and seems to improve clinical outcomes. More investigation, with long-term follow up data and treatment randomization, is necessary to develop clinical consensus for these patients. [less ▲]

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See detailOne tooth-One time (1T1T), immediate loading of posterior single implants with the final crown: Two-year results of a case series.
LAMBERT, France ULiege; Eldafrawy, Maher ULiege; BEKAERT, Sandrine ULiege et al

in International Journal of Oral Implantology: Implantologist (in press)

AIMS: The aim of this study was to evaluate the two-year outcomes of the One Tooth-One Time (1T1T) completely digital workflow, allowing the immediate loading of a single implant in the posterior region ... [more ▼]

AIMS: The aim of this study was to evaluate the two-year outcomes of the One Tooth-One Time (1T1T) completely digital workflow, allowing the immediate loading of a single implant in the posterior region with a final CAD-CAM crown made of a polymer-infiltrated ceramic network (PICN). MATERIALS AND METHODS: A series of 10 implants were placed, and an intra-oral scan was taken after the surgery. A final screw-retained PICN crown was manufactured chair-side and placed the same day in full occlusion. Marginal peri-implant bone changes and soft-tissue health were evaluated, as well as restoration performance using World Dental Federation criteria and Pink and White Esthetic Scores. Patient-related outcome measures (PROMs) and time consumption data were collected. RESULTS: After two years, the implant survival rate was 100%. The debonding of one crown from its Titanium Base led to a 90% prosthodontic survival rate and the remaining crowns were all considered successful. The mean marginal peri-implant bone changes yielded 0.87 (SD: 0.96) and 0.55 (SD: 0.53) mm after one and two years, respectively. Mild or no inflammation of peri-implant soft tissue was observed in most implants. The overall treatment time reached 175 min and PROMs displayed high patient satisfaction. CONCLUSIONS: This study constitutes the first report considering immediate loading of a single implant in the posterior region with a final crown in occlusion. In this case-series, the two-year outcomes of the 1T1T protocol seem rather promising and fulfil patient expectations. However, those preliminary results need to be confirmed by randomized control trials and patient selection is probably a key factor in this procedure success. [less ▲]

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See detailLes pathologies de la liberté (ou la liberté des pathologies) : La ballade de Germain
Englebert, Jérôme ULiege

in Klēsis: Revue Philosophique (in press)

Mon objectif est de soumettre le concept de « pathologies de la liberté » à triple épreuve. 1/ à travers le célèbre conflit historique de la psychiatrie française opposant Henri Ey à Jacques Lacan sur la ... [more ▼]

Mon objectif est de soumettre le concept de « pathologies de la liberté » à triple épreuve. 1/ à travers le célèbre conflit historique de la psychiatrie française opposant Henri Ey à Jacques Lacan sur la présence de la liberté au sein de la maladie mentale ; 2/ à travers l’opposition que nous identifierons entre les méthodes prônées par Binswanger et par Minkowski pour réaliser une compréhension psychopathologique de l’individu ; 3/ à travers la clinique, le cas Germain, patient psychotique dont nous reprendrons l’histoire qui le verra s’opposer au monde entier. Je donnerai différents arguments en analysant ces débats (historiques, méthodologiques et cliniques) afin de proposer une lecture singulière des pathologies de la liberté et de voir comment cette lecture s’inscrit dans le champ psychopathologique. L’objectif de ma contribution sera de rencontrer le vécu en première personne du sujet psychotique qui se retrouve mal dans la qualification de son existence comme étant privée de liberté. Comme le titre de cette étude l’annonce, la thèse que je défends est de considérer que l’interrogation des pathologies de la liberté conduit également à interroger son corollaire, la dimension inéluctablement libre inhérente aux personnes affectées de psychopathologies. Ce décalage, que nous permettra d’entrevoir Lacan, nous mènera à interroger la dimension adaptative de l’expérience psychopathologique et, dans la continuité de Canguilhem, à considérer la pathologie comme la création de normes inédites (généralement inaccessibles à autrui). [less ▲]

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See detailLa question de l’éducation : aiguillon des philosophies politiques. Castoriadis/Rancière.
Wustefeld, Sophie ULiege

in MethIS: Méthodes et Interdisciplinarité en Sciences Humaines (in press)

La démocratie reste un thème chéri par la philosophie politique contemporaine, pour l’écart entre ses théories et ses pratiques, pour la distance critique que ses théories offrent vis-à-vis des régimes ... [more ▼]

La démocratie reste un thème chéri par la philosophie politique contemporaine, pour l’écart entre ses théories et ses pratiques, pour la distance critique que ses théories offrent vis-à-vis des régimes démocratiques et de leur évolution, mais aussi parce qu’elle est un objet perpétuel de dissensus entre philosophes, au sujet duquel toute prétention à la véridiction est suspendue à sa réalisation pratique. À ce titre, la transmission de la volonté démocratique est un topos houleux de la philosophie politique contemporaine. Cette question catalyse les concepts pivots des philosophies politiques, la leur poser permet de mieux saisir les enjeux rivaux derrière une terminologie commune à plusieurs auteurs. C’est dans cette démarche que je vous propose d’examiner en miroir les philosophies de Cornélius Castoriadis et de Jacques Rancière. De plus en plus nombreux, des commentateurs rapprochent leurs pensées , qui peuvent s’appuyer sur plusieurs points communs : un attachement au concept de démocratie brandit contre les régimes parlementaires, une opposition contemporaine (quoique depuis des héritages différents) aux thèses défendues par Althusser, et une proximité de sources d’inspirations : la philosophie, le marxisme, et la psychanalyse. Partant de la manière dont cette proximité s’exprime dans la disjonction que chacun opère entre démocratie et science, je tenterai de discerner comment les inflexions qu’ils impriment aux concepts de volonté et d’égalité sous la guise des enjeux de la transmission dessinent des horizons politiques distincts, et dénotent des compréhensions antithétiques – mais indécidables dans la théorie – de ce que peut être la démocratie. [less ▲]

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See detailUniversal and macro-areal patterns in the lexicon. A case-study in the perception-cognition domain
Georgakopoulos, Athanasios ULiege; Grossman, Eitan; Nikolaev, Dmitri et al

in Linguistic Typology (in press)

This paper investigates universal and areal structures in the lexicon as manifested by colexification patterns in the semantic domains of perception and cognition, based on data from both small and large ... [more ▼]

This paper investigates universal and areal structures in the lexicon as manifested by colexification patterns in the semantic domains of perception and cognition, based on data from both small and large datasets. Using several methods, including weighted semantic maps, formal concept lattices, correlation analysis, and dimensionality reduction, we identify colexification patterns in the domains in question and evaluate the extent to which these patterns are specific to particular areas. This paper contributes to the methodology of investi-gating areal patterns in the lexicon, and identifies a number of cross-linguistic regularities and of area-specific properties in the structuring of lexicons. [less ▲]

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See detailLa Vigna Manzi a Garaguso (MT) : Vecchi scavi, ricerche in corso e prospettive di studio di un importante sito indigeno
Cuvelier, Graham ULiege; Morard, Thomas ULiege; Motta, Lucie

in Siris: Studi e Ticerche della Scuola di Specializzazione in Archeologia di Matera (in press)

This article traces the history of the archaeological research conducted on the site of the Vigna Manzi in Garaguso starting from the excavation of Vittorio Di Cicco in 1916 (which uncovered the famous ... [more ▼]

This article traces the history of the archaeological research conducted on the site of the Vigna Manzi in Garaguso starting from the excavation of Vittorio Di Cicco in 1916 (which uncovered the famous “Dea di Garaguso” and her tempietto) to the five surveys run by Jean-Paul Morel between 1969 and 1970. It then presents the results of the campaign led by Jean-Marc Moret in 2008 as well as the reopening and the prospects of the study of this site by the University of Liège. [less ▲]

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See detailOdanacatib for the treatment of postmenopausal osteoporosis: results of the LOFT multicenter, randomized, double-blind, placebo-controlled trial and LOFT Extension Study
McClung, M.R.; O'Donoghue, M.L.; Papapoulos, S.E. et al

in Lancet Diabetes and Endocrinology (in press)

Background: Odanacatib, a cathepsin K inhibitor, reduces bone resorption while maintaining bone formation. Previous work has shown that odanacatib increases bone mineral density in postmenopausal women ... [more ▼]

Background: Odanacatib, a cathepsin K inhibitor, reduces bone resorption while maintaining bone formation. Previous work has shown that odanacatib increases bone mineral density in postmenopausal women with low bone mass. We aimed to investigate the efficacy and safety of odanacatib to reduce fracture risk in postmenopausal women with osteoporosis. Methods: The Long-term Odanacatib Fracture Trial (LOFT) was a multicentre, randomised, double-blind, placebocontrolled, event-driven study at 388 outpatient clinics in 40 countries. Eligible participants were women aged at least 65 years who were postmenopausal for 5 years or more, with a femoral neck or total hip bone mineral density T-score between –2·5 and –4·0 if no previous radiographic vertebral fracture, or between –1·5 and –4·0 with a previous vertebral fracture. Women with a previous hip fracture, more than one vertebral fracture, or a T-score of less than –4·0 at the total hip or femoral neck were not eligible unless they were unable or unwilling to use approved osteoporosis treatment. Participants were randomly assigned (1:1) to either oral odanacatib (50 mg once per week) or matching placebo. Randomisation was done using an interactive voice recognition system after stratification for previous radiographic vertebral fracture, and treatment was masked to study participants, investigators and their staff, and sponsor personnel. If the study completed before 5 years of double-blind treatment, consenting participants could enrol in a double-blind extension study (LOFT Extension), continuing their original treatment assignment for up to 5 years from randomisation. Primary endpoints were incidence of vertebral fractures as assessed using radiographs collected at baseline, 6 and 12 months, yearly, and at final study visit in participants for whom evaluable radiograph images were available at baseline and at least one other timepoint, and hip and non-vertebral fractures adjudicated as being a result of osteoporosis as assessed by clinical history and radiograph. Safety was assessed in participants who received at least one dose of study drug. The adjudicated cardiovascular safety endpoints were a composite of cardiovascular death, myocardial infarction, or stroke, and new-onset atrial fibrillation or flutter. Individual cardiovascular endpoints and death were also assessed. LOFT and LOFT Extension are registered with ClinicalTrials.gov (number NCT00529373) and the European Clinical Trials Database (EudraCT number 2007-002693-66). Findings: Between Sept 14, 2007, and Nov 17, 2009, we randomly assigned 16 071 evaluable patients to treatment: 8043 to odanacatib and 8028 to placebo. After a median follow-up of 36·5 months (IQR 34·43–40·15) 4297 women assigned to odanacatib and 3960 assigned to placebo enrolled in LOFT Extension (total median follow-up 47·6 months, IQR 35·45–60·06). In LOFT, cumulative incidence of primary outcomes for odanacatib versus placebo were: radiographic vertebral fractures 3·7% (251/6770) versus 7·8% (542/6910), hazard ratio (HR) 0·46, 95% CI 0·40–0·53; hip fractures 0·8% (65/8043) versus 1·6% (125/8028), 0·53, 0·39–0·71; non-vertebral fractures 5·1% (412/8043) versus 6·7% (541/8028), 0·77, 0·68–0·87; all p<0·0001. Combined results from LOFT plus LOFT Extension for cumulative incidence of primary outcomes for odanacatib versus placebo were: radiographic vertebral fractures 4·9% (341/6909) versus 9·6% (675/7011), HR 0·48, 95% CI 0·42–0·55; hip fractures 1·1% (86/8043) versus 2·0% (162/8028), 0·52, 0·40–0·67; non-vertebral fractures 6·4% (512/8043) versus 8·4% (675/8028), 0·74, 0·66–0·83; all p<0·0001. In LOFT, the composite cardiovascular endpoint of cardiovascular death, myocardial infarction, or stroke occurred in 273 (3·4%) of 8043 patients in the odanacatib group versus 245 (3·1%) of 8028 in the placebo group (HR 1·12, 95% CI 0·95–1·34; p=0·18). New-onset atrial fibrillation or flutter occurred in 112 (1·4%) of 8043 patients in the odanacatib group versus 96 (1·2%) of 8028 in the placebo group (HR 1·18, 0·90–1·55; p=0·24). Odanacatib was associated with an increased risk of stroke (1·7% [136/8043] vs 1·3% [104/8028], HR 1·32, 1·02–1·70; p=0·034), but not myocardial infarction (0·7% [60/8043] vs 0·9% [74/8028], HR 0·82, 0·58–1·15; p=0·26). The HR for all-cause mortality was 1·13 (5·0% [401/8043] vs 4·4% [356/8028], 0·98–1·30; p=0·10).When data from LOFT Extension were included, the composite of cardiovascular death, myocardial infarction, or stroke occurred in significantly more patients in the odanacatib group than in the placebo group (401 [5·0%] of 8043 vs 343 [4·3%] of 8028, HR 1·17, 1·02–1·36; p=0·029, as did stroke (2·3% [187/8043] vs 1·7% [137/8028], HR 1·37, 1·10–1·71; p=0·0051). Interpretation: Odanacatib reduced the risk of fracture, but was associated with an increased risk of cardiovascular events, specifically stroke, in postmenopausal women with osteoporosis. Based on the overall balance between benefit and risk, the study’s sponsor decided that they would no longer pursue development of odanacatib for treatment of osteoporosis. [less ▲]

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See detailPsychopathologie et monde social : les limites de l'empathie et de la sympathie
Englebert, Jérôme ULiege

in Philosophie (in press)

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See detailTiwouh: an enriched technology-based solution for communication interventions
Fage, Charles ULiege; Giblet, Sarah ULiege; Jaspard, Marie et al

in Association for the Advancement of Modelling and Simulation Techniques in Enterprises (in press)

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See detailApparent cohesion effects on overtopping-induced fluvial dike breaching
Rifai, Ismail; El Kadi Abderrezzak, Kamal; Hager, Willi et al

in Journal of Hydraulic Research (in press)

Flow overtopping can lead to the initiation of breaching and failure of fluvial dikes, causing severe inundations and damage in the protected areas. For flood risk management and prevention, the accurate ... [more ▼]

Flow overtopping can lead to the initiation of breaching and failure of fluvial dikes, causing severe inundations and damage in the protected areas. For flood risk management and prevention, the accurate estimate of flow discharge across the fluvial dike breach is paramount, requiring the precise understanding of the breach expansion. Laboratory experiments were conducted to analyse the effects of fine sand, inducing apparent cohesion in the dike material, on the breach development and outflow. Tests were conducted under controlled inflow discharge and dike material composed of either homogeneous non-cohesive coarse sand or heterogeneous fine sand/coarse sand mixtures. Based on the non-intrusive Laser Profilometry technique, high temporal and spatial resolution of the three-dimensional breach geometry evolution was measured, indicating a small effect of the fine material on the overall breach dynamics. A detailed analysis revealed, however, that fine sand induces less frequent slope collapses but larger sliding/failing lumps compared to homogenous non-cohesive coarse sand. [less ▲]

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See detailEvent Representations and Predictive Processing: The Role of the Midline Default Network Core
Stawarczyk, David ULiege; Bezdek, Matthew A.; Zacks, Jeffrey M.

in Topics in Cognitive Science (in press)

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See detailPotential for the use of lactoperoxidase against post-harvest diseases on fruit
Bafort, Françoise ULiege; Perraudin, Jean-Paul; Jijakli, Haissam ULiege

in Acta Horticulturae (in press)

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See detailRadical-Pairing Interactions in a Molecular Switch Evidenced by Ion Mobility Spectrometry and Infrared Ion Spectroscopy
Hanozin, Emeline ULiege; Mignolet, Benoît ULiege; Martens, Jonathan et al

in Angewandte Chemie International Edition (in press)

The digital revolution sets a milestone in the progressive miniaturization of working devices and in the underlying advent of molecular machines. Foldamers involving mechanically entangled components with ... [more ▼]

The digital revolution sets a milestone in the progressive miniaturization of working devices and in the underlying advent of molecular machines. Foldamers involving mechanically entangled components with modular secondary structures are among the most promising designs for molecular switch-based applications. Characterizing the nature and dynamics of their intramolecular network following the application of a stimulus is the key to their performance. Here, we use non-dissociative electron transfers as a reductive stimulus in the gas phase and probe the consecutive co-conformational transitions of a donor-acceptor oligorotaxane foldamer using electrospray mass spectrometry interfaced with ion mobility and infrared ion spectroscopy. The comparison of collision cross section distributions for analogous closed-shell and radical molecular ions sheds light on their respective formation energetics while variations in their respective infrared absorption bands evidence different intramolecular organizations as the foldamer gets compact. These differences are compatible with the advent of radical-pairing interactions. [less ▲]

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See detailIntégrer le droit international au champ des relations internationales : les juristes belges à Versailles en 1919
Genin, Vincent ULiege

in Relations internationales (in press), (2),

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See detailPolicy narratives and megaprojects: the case of the Lyon-Turin high-speed railway
Esposito, Giovanni ULiege; Terlizzi, Andrea; Crutzen, Nathalie ULiege

in Public Management Review (in press)

This article investigates how policy narratives developed by proponents and opponents of infrastructure megaprojects generate controversies that affect the megaproject implementation. Drawing evidence ... [more ▼]

This article investigates how policy narratives developed by proponents and opponents of infrastructure megaprojects generate controversies that affect the megaproject implementation. Drawing evidence from the Lyon-Turin high-speed railway, we argue that megaproject implementation is a complex public management endeavour which can hardly be considered a rational, straightforward process. It is rather a non-linear process involving stakeholders with divergent interests and logics of action engaging in a battle over competing narratives to influence implementation outcomes. Institutional settings opened to opponents’ voice in megaproject decision-making facilitate and streamline the resolution of controversies, whereas difficult and conflictual conditions emerge in the opposite case. [less ▲]

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See detailL’œil du cycle. Réseaux textuels et stemmata codicum dans la tradition des textes arthuriens
Morato, Nicola ULiege

in Encomia : Bulletin Bibliographique de la Société Internationale de Littérature Courtoise (in press)

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See detailEditing Letters from Deir el-Medina: A Preliminary Report
Sojic, Nathalie ULiege

in Rivista del Museo Egizio (in press)

This article is a preliminary report on the in-progress publication of unpublished letters written on ostraca coming from Deir el-Medina. It is structured in three parts. The first section provides ... [more ▼]

This article is a preliminary report on the in-progress publication of unpublished letters written on ostraca coming from Deir el-Medina. It is structured in three parts. The first section provides archaeological and material data on the objects. The second section proposes a typology of the documentation, thus illustrating the interest of a documentary study of the sources to better understand the scribal practices of the time. The third section briefly presents the research perspectives offered by the corpus. [less ▲]

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See detailFictions de l’œuvre. Projets et textes possibles dans les romans de la vie littéraire
Saint-Amand, Denis ULiege

in Cahiers ReMIX (in press)

Le monde des études littéraires a vu se développer, au cours de ces dernières années, une théorie des textes possibles qui confronte la réception traditionnelle des œuvres (c’est-à-dire la façon dont leur ... [more ▼]

Le monde des études littéraires a vu se développer, au cours de ces dernières années, une théorie des textes possibles qui confronte la réception traditionnelle des œuvres (c’est-à-dire la façon dont leur lecture se concrétise la plupart du temps et le commentaire qu’on en livre habituellement) à une réinvention de leur signification, tirant parti des impensés de la fiction, des non-dits, des interactions interrompues, des blancs, des inférences labiles et autres zones creuses du récit qui offrent des prises pour une renégociation herméneutique. À côté des réinventions herméneutiques des œuvres classiques, de l’approche génétique et du fantasme programmatique autour des productions perdues, la critique des textes possibles aurait tout à gagner à explorer un continent fictionnel, fructueux en termes d’œuvres en puissance et qui recèle d’indications sur l’évaluation des modes et tendances d’une époque émanant des représentations des écrivains eux-mêmes : les œuvres imaginaires qui n’existent qu’en tant qu’elles sont inscrites dans d’autres œuvres, qui en esquissent les contours, les présentent voire les citent. Celles-là sont au cœur de la présente enquête, menée à partir du corpus rassemblé dans la base de données du GREMLIN ; on interroge dans cette contribution la façon dont, par métonymie, elles contribuent à une représentation fictionnelle de la vie littéraire. [less ▲]

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See detailReducibility of n-ary semigroups: from quasitriviality towards idempotency
Couceiro, Miguel; Devillet, Jimmy; Marichal, Jean-Luc et al

in Beiträge zur Algebra und Geometrie (in press)

Let $X$ be a nonempty set. Denote by $\mathcal{F}^n_k$ the class of associative operations $F\colon X^n\to X$ satisfying the condition $F(x_1,\ldots,x_n)\in\{x_1,\ldots,x_n\}$ whenever at least $k$ of the ... [more ▼]

Let $X$ be a nonempty set. Denote by $\mathcal{F}^n_k$ the class of associative operations $F\colon X^n\to X$ satisfying the condition $F(x_1,\ldots,x_n)\in\{x_1,\ldots,x_n\}$ whenever at least $k$ of the elements $x_1,\ldots,x_n$ are equal to each other. The elements of $\mathcal{F}^n_1$ are said to be quasitrivial and those of $\mathcal{F}^n_n$ are said to be idempotent. We show that $\mathcal{F}^n_1=\cdots =\mathcal{F}^n_{n-2}\subseteq\mathcal{F}^n_{n-1}\subseteq\mathcal{F}^n_n$ and we give conditions on the set $X$ for the last inclusions to be strict. The class $\mathcal{F}^n_1$ was recently characterized by Couceiro and Devillet \cite{CouDev}, who showed that its elements are reducible to binary associative operations. However, some elements of $\mathcal{F}^n_n$ are not reducible. In this paper, we characterize the class $\mathcal{F}^n_{n-1}\setminus\mathcal{F}^n_1$ and show that its elements are reducible. We give a full description of the corresponding reductions and show how each of them is built from a quasitrivial semigroup and an Abelian group whose exponent divides $n-1$. [less ▲]

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See detailUn fragment de papier copte relatif à Jésus conservé à Liège : P.Leod. coll. priv. inv. 138
Carlig, Nathan ULiege

in Journal of Coptic Studies (in press)

Édition, traduction et commentaire d'un fragment de papier copte (XIIe/XIIIe s.) conservé à Centre de Documentation de Papyrologie Littéraire (CEDOPAL) de l'Université de Liège.

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See detailActivation comportementale: un traitement des ruminations
Blairy, Sylvie ULiege

in santé mentale (in press)

L’activation comportementale fait partie des traitements de la rumination mentale. Le comportement de rumination mentale peut être un évitement expérientiel dont le thérapeute et le patient devront en ... [more ▼]

L’activation comportementale fait partie des traitements de la rumination mentale. Le comportement de rumination mentale peut être un évitement expérientiel dont le thérapeute et le patient devront en faire l’analyse fonctionnelle. Au cours de l’analyse, le patient identifiera l’expérience émotionnelle aversive qu’il tente d’éviter et des comportements alternatifs à la rumination seront envisagés et planifiés. L’activation comportementale est un traitement bien accepté par les patients. [less ▲]

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See detailOptimization and validation of HS-SPME-GC-MS for the determination of Furan and Alkylfurans in chocolate-based products: Impact of tempering and laser printing
Alsafra, Zouheir ULiege; Scholl, Georges ULiege; Eppe, Gauthier ULiege

in Journal of AOAC International (in press)

Objectives Two major objectives are presented. Firstly, we aim at optimizing and validating a HS-SPME-GC-MS method for the quantification of 5 alkylfurans in chocolate. Secondly, we focus our study on ... [more ▼]

Objectives Two major objectives are presented. Firstly, we aim at optimizing and validating a HS-SPME-GC-MS method for the quantification of 5 alkylfurans in chocolate. Secondly, we focus our study on measuring the quantitative impact of engraving technique on the formation of furan and its derivatives in chocolate, from the raw callets to processed end-products. Method HS-SPME-GC-MS method operating in SIM mode and using isotope dilution technique with deuterated homologue internal standards was used to quantify alkylfurans in chocolate. Results Good repeatability (RSD% = 0.1-8%, in duplicate) and intermediate precision (RSD% = 1.7-7%, n = 6) were obtained for these five process contaminants at 10, 25, and 50 µg/kg. Trueness was varying between 81 and 109%. LoQ ranged from 0.48 to 2.50 µg/kg. Relative expanded measurement uncertainties ranged from 6 to 30%. Finally, tempering is responsible for a 24% increase in furan contamination, while the laser engraving technique results in an additional 31% increase in furan. A similar trend was also observed for 2-methylfuran and 3-methylfuran, whereas no significant increases were observed for 2,3-dimethylfuran and 2,5-dimethylfuran. Conclusions and highlights A reliable and sensitive method of HS-SPME-GC-MS was reported for the first time for the analysis of furan and four alkylfurans in chocolate. This paper demonstrated that engraving using laser-based techniques can increase the levels of these compounds by up to 30%. [less ▲]

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See detailPratiques éducatives parentales et premières compétences en numératie des enfants d’âge préscolaire selon le niveau socio-économique et culturel des familles
Poncelet, Débora; de Chambrier, Anne-Françoise; Tinnes-Vigne, Mélanie et al

in Revue Internationale de l'Education Familiale (in press)

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See detailL’expertise médico-légale dans l’Antiquité : le témoignage des papyrus grecs d’Égypte
Ricciardetto, Antonio ULiege

in Histoire, Médecine et Santé (in press)

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See detailInfluence of back-mixing on the convective drying of sewage sludge: The structural characteristics
Li, Jie; Fraikin, Laurent ULiege; Salmon, Thierry ULiege et al

in Drying Technology (in press)

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See detailThe vocabulary of care and healing in the Greek private letters of Byzantine Egypt
Ricciardetto, Antonio ULiege

in Trends in Classics (in press)

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See detailLes références à la couleur dans les textes hippiatriques grecs
Ricciardetto, Antonio ULiege

in Pallas: Revue d'Études Antiques (in press)

Based on a survey references to colours in Greek hippiatrics text—especially in the Hippiatrica and in book 16 of the Geoponica—this paper examines the lexicon used by horsedoctors to designate colour and ... [more ▼]

Based on a survey references to colours in Greek hippiatrics text—especially in the Hippiatrica and in book 16 of the Geoponica—this paper examines the lexicon used by horsedoctors to designate colour and the contexts in which it appears, in order to better understand the importance given to colour terms. Colour adjectives are used in three sections of the texts: the external description of the animal (especially the coat and eyes), body fluids and pharmacology (simple and compound drugs). [less ▲]

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See detailContact Pressure Between the Vocal Folds in Reinke’s Edema: Experimental Observations on an Excised Human Larynx
SILVA, FABRICE; LEGOU, THIERRY; CHAMPSAUR, PIERRE et al

in Journal of Voice (in press)

Objective. To analyze the range of values of the contact pressure between the membranous vocal folds with Reinke’s edema and to compare it to those observed in the absence of such a lesion. Methods. Two ... [more ▼]

Objective. To analyze the range of values of the contact pressure between the membranous vocal folds with Reinke’s edema and to compare it to those observed in the absence of such a lesion. Methods. Two human larynges were separately tested on the experimental bench, one of them with a bilateral loose swelling of the vocal folds. Once in a glottal prephonatory configuration, airflow was increased until achievement of self-sustained oscillations while recording aerodynamic, acoustic, electroglottographic data, and contact pressure between the folds. Results. We observed well-documented variations in acoustical parameters, as the decrease of the fundamental frequency and the increase of the phonation threshold pressure. The results of the study also point to a significant increase in the amplitude of the contact pressure in presence of the Reinke’s edema, and a lower degree of harmonicity of the produced sounds. Conclusion. This is the first report of ex vivo study of a larynx with Reinke’s edema. It highlights the increase in the contact pressure during phonation, which possibly contributes to sustain the lesion once it appeared. [less ▲]

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See detailThe vector-apodizing phase plate coronagraph: design, current performance, and future development
Doelman, D. S.; Snik, F.; Por, E. H. et al

in Applied Optics (in press)

Over the last decade, the vector-apodizing phase plate (vAPP) coronagraph has been developed from concept to on-sky application in many high-contrast imaging systems on 8-m class telescopes. The vAPP is ... [more ▼]

Over the last decade, the vector-apodizing phase plate (vAPP) coronagraph has been developed from concept to on-sky application in many high-contrast imaging systems on 8-m class telescopes. The vAPP is an geometric-phase patterned coronagraph that is inherently broadband, and its manufacturing is enabled only by direct-write technology for liquid-crystal patterns. The vAPP generates two coronagraphic PSFs that cancel starlight on opposite sides of the point spread function (PSF) and have opposite circular polarization states. The efficiency, that is the amount of light in these PSFs, depends on the retardance offset from half-wave of the liquid-crystal retarder. Using different liquid-crystal recipes to tune the retardance, different vAPPs operate with high efficiencies ($>96\%$) in the visible and thermal infrared (0.55 $\mu$m to 5 $\mu$m). Since 2015, seven vAPPs have been installed in a total of six different instruments, including Magellan/MagAO, Magellan/MagAO-X, Subaru/SCExAO, and LBT/LMIRcam. Using two integral field spectrographs installed on the latter two instruments, these vAPPs can provide low-resolution spectra (R$\sim$30) between 1 $\mu$m and 5 $\mu$m. We review the design process, development, commissioning, on-sky performance, and first scientific results of all commissioned vAPPs. We report on the lessons learned and conclude with perspectives for future developments and applications. [less ▲]

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See detailCompte-rendu de l'ouvrage de Bénédicte DELIGNON : La morale de l’amour dans les Odes d’Horace : poésie, philosophie et politique, Paris, Sorbonne Université Presses, 2019.
Amilien, Arnaud ULiege

in Antiquité Classique (in press), 90

In this book, Bénédicte Delignon shows that Horatius introduces a moral dimension in his Ods described as "erotica". According to her, it would have taken place in Augustus's project of redressing the ... [more ▼]

In this book, Bénédicte Delignon shows that Horatius introduces a moral dimension in his Ods described as "erotica". According to her, it would have taken place in Augustus's project of redressing the Roman morality (the “mos maiorum”). The erotic Ods are thus pieces combining love with politics and moral philosophy and singing the Princeps as well as his restoration of order. [less ▲]

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See detailRecherches sur le Site de Germigny-des-Prés en 2019
Van Wersch, Line ULiege; Henrion, Fabrice

in Bilan scientifique de la région Centre-Val de Loire (in press), 2019

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See detailLa transe cognitive auto-induite : caractéristiques et applications thérapeutiques potentielles.
Grégoire, Charlotte ULiege; Sombrun, Corine; Gosseries, Olivia ULiege et al

in HEGEL: Penser par Soi-Même (in press)

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See detailProspective association between diabetes diagnosis, HbA1c, glycaemia and frailty trajectories in an elderly population
Aguayo Diaz, Gloria ULiege; Hulman, Adam; Vaillant, Michel et al

in Diabetes Care (in press)

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See detailA new approach to constrain the seismic origin for prehistoric turbidites as applied to the Dead Sea Basin
Lu, Yin; Moernaut, Jasper; Bookman, Revital et al

in Geophysical Research Letters (in press)

The seismic origin of turbidites is verified either by correlating such layers to historic earthquakes, or by demonstrating their synchronous deposition in widely spaced, isolated depocenters. The ... [more ▼]

The seismic origin of turbidites is verified either by correlating such layers to historic earthquakes, or by demonstrating their synchronous deposition in widely spaced, isolated depocenters. The historic correlation could thus constrain the seismic intensity required for triggering turbidites. However, the historic calibration is not applicable to prehistoric turbidites. In addition, the synchronous deposition of turbidites is difficult to prove if only one deep core is drilled in a depocenter. Here, we propose a new approach that involves analyzing the underlying in situ deformations of prehistoric turbidites recorded in a 457 m-long core from the Dead Sea center, in order to establish their seismic origin. These in situ deformations have been verified as seismites and could thus authenticate the trigger for each overlying turbidite. Moreover, our high-resolution chemical and sedimentological data validate the previous hypothesis that Dead Sea soft-sediment deformations formed at the sediment-water interface. [less ▲]

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See detailImpact of Different Kinds of Child Abuse on Sense of Parental Competence in Parents Who Were Abused in Childhood
Baiverlin, Audrey ULiege; Gallo, Alicia ULiege; Blavier, Adelaïde ULiege

in European Journal of Trauma and Dissociation (in press)

The purpose of this article is to study sense of parental competence in parents who experienced abuse in childhood. Many studies have shown that the kind of abuse (physical, emotional, sexual, neglect ... [more ▼]

The purpose of this article is to study sense of parental competence in parents who experienced abuse in childhood. Many studies have shown that the kind of abuse (physical, emotional, sexual, neglect) that the parent experienced in childhood and the co-occurrence of several types of abuse affect the sense of parental competence. In particular, we focused on the difference between sexual abuse and other kinds of abuse. The instruments used to collect data were the French versions of the Childhood Trauma Questionnaire, which assesses abuse, and the Parenting Sense of Competence Scale, which assesses efficacy and satisfaction. These questionnaires were designed to quantitatively evaluate the kind of abuse experienced during childhood and the sense of parental competence. We collected 828 valid protocols. The statistical analyses show that sense of parental competence is lower in parents who were abused during their childhood than in those who were not. More specifically, our results show that these parents feel less satisfaction, one of the two components of the sense of parental competence. [less ▲]

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See detailL'efficacité de la thérapie est-elle modulée par la relation thérapeutique en fonction du motif de consultation ?
Baiverlin, Audrey ULiege; Piquet, E.; Delhalle, Manon ULiege et al

in Evolution Psychiatrique (in press)

Ce travail de recherche a pour objectif principal d’évaluer l’efficacité de la thérapie brève en fonction du motif de consultation. L’originalité de cette étude est qu’elle met en lumière certains ... [more ▼]

Ce travail de recherche a pour objectif principal d’évaluer l’efficacité de la thérapie brève en fonction du motif de consultation. L’originalité de cette étude est qu’elle met en lumière certains processus qui rendent la thérapie brève efficace, en s’intéressant notamment aux aspects relationnels de la thérapie et ce, en questionnant les impressions des patients. En outre, cette étude évalue les effets à long moyen terme de la thérapie brève (3 mois après la thérapie), distingue les thérapies mises en place dans l’intérêt d’un adulte ou d’un enfant et tient compte du motif de consultation (souffrance relationnelle, liée à une pathologie ou encore liée au contexte professionnel ou scolaire). Nous avons récolté 110 protocoles complétés et nos résultats mettent en évidence que les patients se montrent en grande majorité satisfaits de la thérapie brève, quelle que soit leur motif de consultation (souffrance relationnelle, liée à une pathologie ou encore liée au contexte professionnel ou scolaire) et qu’elle soit mise en place dans l’intérêt d’un enfant ou d’un adulte. En outre, le changement positif engendré par la thérapie brève se maintient dans le temps (après 3 mois) et est même encore plus prononcé. Toutefois, la moitié des personnes interrogées rapportent rencontrer des « rechutes » du motif pour lequel elles sont venues consulter, mais ces rechutes sont moins fréquentes et moins intenses. Les patients rapportent en effet pouvoir réagir plus efficacement aux rechutes grâce au changement induit par la thérapie brève et stratégique. Enfin, les aspects relationnels de la thérapie que nous avons évalués jouent un rôle majeur dans le résultat de la thérapie et ce, pour tous les patients quelle que soit leur motif de consultation et qu’elle concerne un enfant ou un adulte. Nous avons ainsi pu mettre en évidence des aspects de la thérapie brève et stratégique jugés par les patients comme essentiels afin de garantir la satisfaction de la prise en charge et, par-là, l’efficacité. La mise en évidence de ces facteurs permet des ajustements cliniques intéressants pour les thérapeutes. [less ▲]

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See detailPRISE EN CHARGE CHIRURGICALE DE LA MALADIE D’OTTO CHEZ L’ENFANT
Kabore, Christophe ULiege; Allington, Nanni ULiege

in Ortho-Rhumato (in press)

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See detailOpto-electronic properties and solar cell efficiency modelling of Cu2ZnXS4 (X=Sn,Ge,Si) kesterites
Ratz, Thomas ULiege; Raty, Jean-Yves ULiege; Brammertz, Guy et al

in Journal of Physics : Energy (in press)

In this work, first-principles calculations of Cu2ZnSnS4, Cu2ZnGeS4 and Cu2ZnSiS4 are per- formed to highlight the impact of the cationic substitution on the structural, electronic and optical properties ... [more ▼]

In this work, first-principles calculations of Cu2ZnSnS4, Cu2ZnGeS4 and Cu2ZnSiS4 are per- formed to highlight the impact of the cationic substitution on the structural, electronic and optical properties of kesterite compounds. Direct bandgaps are reported with values of 1.32, 1.89 and 3.06 eV respectively for Cu2ZnSnS4, Cu2ZnGeS4 and Cu2ZnSiS4 and absorption coefficients of the order of 10^4 cm−1 are obtained, indicating the applicability of these materials as absorber layer for solar cell applications. In the second part of this study, ab initio results are used as input data to model the electrical power conversion efficiency of kesterite-based solar cells. In that perspective, we used an improved version of the Shockley-Queisser model including non-radiative recombination via an external parameter defined as the internal quantum efficiency. Based on predicted optimal absorber layer thicknesses, the variation of the solar cell maximal efficiency is studied as a function of the non-radiative recombination rate. Maximal efficiencies of 25.71, 19.85 and 3.10 % are reported respectively for Cu2ZnSnS4, Cu2ZnGeS4 and Cu2ZnSiS4 for vanishing non-radiative recombination rate. Using an internal quantum efficiency value providing experimentally comparable VOC values, cell efficiencies of 15.88, 14.98 and 2.66 % are reported respectively for Cu2ZnSnS4, Cu2ZnGeS4 and Cu2ZnSiS4. We confirm the suitability of Cu2ZnSnS4 in single junction solar cells, with a possible efficiency improvement of nearly 10% enabled through the reduction of the non-radiative recombination rate. In addition, Cu2ZnGeS4 appears to be an interesting candidate as top cell absorber layer for tandem approaches whereas Cu2ZnSiS4 might be interesting for transparent photovoltaic windows. [less ▲]

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See detailResponsabilité pénale des personnes morales
Jacobs, Ann ULiege; Dister, Jean-François; Thevissen, Patrick ULiege et al

in Postal Memorialis (in press)

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See detailCompte rendu de l'ouvrage de Ch. Veyrard-Cosme : Alcuin, Lettres. Tome 1
Close, Florence ULiege

in Revue d'Histoire Ecclésiastique (in press)

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See detailCharacterizing the gradients of structural covariance in the human hippocampus.
Kharabian Masouleh, Shahrzad; Plachti, Anna; Hoffstaedter, Felix et al

in NeuroImage (in press)

The hippocampus is a plastic brain structure that has been associated with a range of behavioral aspects but also shows vulnerability to the most frequent neurocognitive diseases. Different aspects of its ... [more ▼]

The hippocampus is a plastic brain structure that has been associated with a range of behavioral aspects but also shows vulnerability to the most frequent neurocognitive diseases. Different aspects of its organization have been revealed by studies probing its different neurobiological properties. In particular, histological work has shown a pattern of differentiation along the proximal-distal dimension, while studies examining functional properties and large-scale functional integration have primarily highlighted a pattern of differentiation along the anterior posterior dimension. To better understand how these organizational dimensions underlie the pattern of structural covariance (SC) in the human hippocampus, we here applied a non-linear decomposition approach, disentangling the major modes of variation, to the pattern of grey matter volume correlation of hippocampus voxels with the rest of the brain in a sample of 377 healthy young adults. We additionally investigated the consistency of the derived gradients in an independent sample of life-span adults and also examined the relationships between these major modes of variations and the patterns derived from microstructure and functional connectivity mapping. Our results showed that similar major modes of SC-variability are identified across the two independent datasets. The major dimension of variation found in SC runs along the hippocampal anterior-posterior axis and followed closely the principal dimension of functional differentiation, suggesting an influence of network level interaction in this major mode of morphological variability. The second main mode of variability in the SC showed a gradient along the dorsal-ventral axis, and was moderately related to variability in hippocampal microstructural properties. Thus our results depicting relatively reliable patterns of SC variability within the hippocampus show an interplay between the already known organizational principles on the pattern of variability in hippocampus’ macrostructural properties. This study hence provides a first insight on the underlying organizational forces generating different co-plastic modes within the human hippocampus that may, in turn, help to better understand different vulnerability patterns of this crucial structure in different neurological and psychiatric diseases. [less ▲]

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See detailNewborn screening programs for spinal muscular atrophy worldwide: where we stand and where to go
Dangouloff, Tamara ULiege; Vrščaj, Eva; Servais, Laurent ULiege et al

in Neuromuscular Disorders (in press)

Spinal muscular atrophy (SMA) is a rare and devastating disease. New disease- modifying treatments have recently been approved and early treatment has been related to a better outcome. In this context ... [more ▼]

Spinal muscular atrophy (SMA) is a rare and devastating disease. New disease- modifying treatments have recently been approved and early treatment has been related to a better outcome. In this context, several newborn screening (NBS) programs have been implemented. The aim of the study was to obtain a global overview on the current situation and perspectives on SMA NBS. We conducted a survey and contacted experts from 152 countries, from which we gathered 87 responses. We identified 9 SMA NBS programs that have so far detected 288 newborns with SMA out of 3,674,277 newborns screened. Funding, screening methods, organisation, and consent process were variable between SMA NBS programs. Many respondents pointed the lack of cost/benefit data as a major obstacle to SMA NBS implementation. In the next four years, our data suggest a 24 % coverage of newborns from countries where a disease-modifying drug is available and 8,5 % coverage in countries with no diseases-modifying drugs. The annual proportion of newborns to be screened in the coming years is expected to increase steadily. The experts expressed a strong need for the implementation of SMA NBS as means to improve care for patients with SMA. [less ▲]

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See detailDigital growth Strategies at Drone Racing League
Standaert, Willem ULiege

in Journal of Information Technology Teaching Cases (in press)

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See detailA Review of Single-Photon Avalanche Diode Time-of-Flight Imaging Sensor Arrays
Piron, François ULiege; Morrison, Daniel; Yuce, Mehmet Rasit et al

in IEEE Sensors Journal (in press)

Time-of-flight (ToF) sensors using light pulses or continuous waves allow accurate distance measurements. Three-dimensional imagers can be based on an array of timing or time-gated integration pixels ... [more ▼]

Time-of-flight (ToF) sensors using light pulses or continuous waves allow accurate distance measurements. Three-dimensional imagers can be based on an array of timing or time-gated integration pixels. Single-photon avalanche diodes (SPADs) have been increasingly chosen as the pixel’s photodetector device to develop fast, long-range ToF sensors. Solid-state ToF cameras are replacing other alternatives, showing attractive characteristics and bringing up new potential applications. This paper presents the technical evolution of SPAD ToF 3D imaging sensors, and provides insight into their development over the last few decades. Starting with the first SPAD imagers reported in the early 2000’s, various direct and indirect arrays up to present day state-of-the-art prototypes are referenced. The existing methods, options and possible implementations are described, addressing their advantages and drawbacks, and showing the progress yet to be made. The performance of the different presented approaches are given and compared. [less ▲]

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See detailLimnological changes in Lake Victoria since the mid-20th century
Deirmendjian; Descy, Jean-Pierre ULiege; Morana, Cédric ULiege et al

in Freshwater Biology (in press)

1. Lake Victoria experienced a strong degradation of water quality between the 1960s and the 1990s and, as a consequence of eutrophication, the dominant phytoplankton group changed from diatoms to N2 ... [more ▼]

1. Lake Victoria experienced a strong degradation of water quality between the 1960s and the 1990s and, as a consequence of eutrophication, the dominant phytoplankton group changed from diatoms to N2-fixing cyanobacteria and there was a 2- to 10-fold increase in Chlorophyll-a. The goal of this study is to determine whether the 2018-2019 physical- (light, stratification) and ecological- (nutrient, Chlorophyll-a, phytoplankton composition) conditions in Lake Victoria changed from the 1990s. 2. Samples were collected in 2018-2019 in nearshore and offshore waters (Uganda), during three contrasting seasons: heavy rains (March), low rains (October) and dry (June), which corresponded to distinct water column mixing regimes, respectively, late-stratified, early-stratified and mixed regimes. At each station (48 nearshore and 25 offshore), we measured vertical profiles of temperature, oxygen, phytoplankton biomass and composition, inorganic nutrients, and particulate organic carbon, particulate nitrogen (PN) and phosphorus. 3. Chlorophyll-a concentrations in 2018-2019 were 10.3±7.1 and 2.8±1.1 µg L-1 in the nearshore and offshore surface waters, respectively, close to those measured in the 1960s before eutrophication, but distinctly lower than those measured in the 1990s (71±100 and 14±6 µg L-1). The phytoplankton of Lake Victoria in 2018-2019 still appears dominated by diatoms and cyanobacteria, but diatoms develop better in stratified conditions whereas cyanobacteria develop better in mixing conditions in comparison with the historical observations. Accordingly, we observed more non-heterocystous filamentous and coccal/colonial cyanobacteria taxa that are better adapted to mixing conditions than gas-vacuolated heterocystous taxa, which were dominant in the 1990s. PN in 2018-2019 decreased significantly compared to the 1990s, indicative of less efficient nitrogen (N) fixation. The dissolved silica (DSi) concentrations in 2018-2019 increased significantly with the concomitant reappearance of Aulacoseira spp., which was not observed in the 1990s, presumably due to low DSi concentrations. 4. As data from long-term monitoring are missing, the reasons for the lower Chlorophyll-a concentrations in 2018-2019 compared to the 1990s are unclear. Bottom-up (nutrients) and top-down (grazing) controls on Chlorophyll-a concentrations were both unlikely. Therefore, climatic controls appear (El Niño/ La Niña conditions) as an important factor to understand the historical trend in Chlorophyll-a. Higher wind in 2018-2019 promoted vertical mixing resulting in a deeper thermocline and surface mixed layers, which eventually lowered phytoplankton production in comparison to the 1990s. In contrast, the thermocline and surface mixed layers in the 1990s were shallower, enabling phytoplankton to stay suspended in the upper well illuminated water, allowing greater productivity. The lake in 2018-2019 is still in conditions of phosphorus (P) saturation, which suggests that another episode of high Chlorophyll-a concentrations could develop if less windy conditions occur in future, as during the 1980s and the 1990s, or if continued warming of surface waters eventually overcomes the mixing from present windy conditions. 5. This study gives insights about the present ecological functioning of the lake and stresses the impacts of variations in climate on lake physics that changes the light environment for phytoplankton. We also provide a biogeochemical data set, which could contribute to a baseline survey for following the ecological changes in Lake Victoria. [less ▲]

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See detailHigh contrast imaging at 10 microns, a search for exoplanets around: Eps Indi A, Eps Eri, Tau Ceti, Sirius A and Sirius B
Pathak, P.; Petit dit de la Roche, D. J. M.; Kasper, M. et al

in Astronomy and Astrophysics (in press)

The direct imaging of rocky exoplanets is one of the major science goals for upcoming large telescopes. The contrast requirement for imaging such planets is challenging. However, the mid-IR (InfraRed ... [more ▼]

The direct imaging of rocky exoplanets is one of the major science goals for upcoming large telescopes. The contrast requirement for imaging such planets is challenging. However, the mid-IR (InfraRed) regime provides the optimum contrast to directly detect the thermal signatures of exoplanets in our solar neighbourhood. We aim to exploit novel fast chopping techniques newly developed for astronomy with the aid of adaptive optics to look for thermal signatures of exoplanets around bright stars in the solar neighbourhood. We use the upgraded VISIR (Very Large Telescope Imager and Spectrometer for the mid-InfraRed) instrument with high contrast imaging (HCI) capability optimized for observations at 10~$\mu$m to look for exoplanets around five nearby ($d$ < 4 pc) stars. The instrument provides an improved signal-to-noise (S/N) by a factor of $\sim$4 in the N-band compared to standard VISIR for a given S/N and time. In this work we achieve a detection sensitivity of sub-mJy, which is sufficient to detect few Jupiter mass planets in nearby systems. Although no detections are made we achieve most sensitive limits within $<2''$ for all the observed targets compared to previous campaigns. For $\epsilon$ Indi A and $\epsilon$ Eri we achieve detection limits very close to the giant planets discovered by RV, with the limits on $\epsilon$ Indi A being the most sensitive to date. Our non-detection therefore supports an older age for $\epsilon$ Indi A. The results presented here show the promise for high contrast imaging and exoplanet detections in the mid-IR regime. [less ▲]

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See detailRewording the World or Reworlding the Word? Some Postcolonial Perspectives on the "World" of World Literature
Gerday, Laura ULiege

in Interventions: the International Journal of Postcolonial Studies (in press)

There appears to be no consensus as yet on the meaning of the term "world" in "world literature". Over the last few years, "world" has indeed been the object of a multitude of responses and readings ... [more ▼]

There appears to be no consensus as yet on the meaning of the term "world" in "world literature". Over the last few years, "world" has indeed been the object of a multitude of responses and readings, which markedly vary according to researchers’ academic backgrounds and theoretical vantage points. How then is the "world" of "world literature" to be apprehended? Combining linguistics-informed and close-reading methods, the present essay seeks to shed light on a notional issue that has especially divided world and postcolonial literary scholars in recent times. More precisely, it will be argued that "world" in the phrase "world literature" has begun to undergo a linguistic process of re-semanticization, whereby this lexical item has come to encode, and be imbued with, values central to the postcolonial agenda – thus providing the postcolonial cause with fresh impetus in the twenty-first century. [less ▲]

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See detailLes critiques chrétiennes des lectisternes et sellisternes romains : un banquet trop anthropomorphe ?
Berthelet, Yann ULiege

in Les Cahiers du CEDOPAL (in press)

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See detailThe influence of interorganizational collaboration on logic conciliation and tensions within hybrid organizations: insights from social enterprise-corporate collaborations
Savarese, Claudia ULiege; Huybrechts, Benjamin ULiege; Hudon, Marek

in Journal of Business Ethics (in press)

An increasing amount of research has examined the management of competing logics, and possible tensions arising between them, within “hybrid organizations”. However, the ways in which the relationships of ... [more ▼]

An increasing amount of research has examined the management of competing logics, and possible tensions arising between them, within “hybrid organizations”. However, the ways in which the relationships of hybrids with other organizations shape the conciliation of these logics and tensions has received limited attention so far. In this theoretical paper, we examine how hybrid organizations deal with interorganizational collaboration, in particular whether and how their hybridity can be maintained when they partner with “dominant-logic organizations”. Drawing on empirical literature on social enterprise-corporate collaborations, we develop a framework and several propositions on how competing logics and their balancing within hybrid organizations may be affected by interactions with organizations underpinned by one dominant logic. We suggest that influences will mostly depend on the type of collaboration pursued. A collaboration based on a lower level of engagement and interaction between the two partners is likely to give precedence to one logic over the other, reducing inter-logic tensions but possibly compromising organizational hybridity. By contrast, a collaboration featuring numerous interactions and mission compatibility may facilitate sustained hybridity if tensions are acknowledged and managed. Our propositions contribute to the literatures on hybrid organizations, interorganizational collaboration, and social enterprise. [less ▲]

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See detailHow has COVID-19 affected the treatment of osteoporosis? An IOF-NOF-ESCEO global survey
Fuggle, N. R.; Singer, A.; Gill, C. et al

in Osteoporosis International (in press)

Summary: The effects of COVID-19 have the potential to impact on the management of chronic diseases including osteoporosis. A global survey has demonstrated that these impacts include an increase in ... [more ▼]

Summary: The effects of COVID-19 have the potential to impact on the management of chronic diseases including osteoporosis. A global survey has demonstrated that these impacts include an increase in telemedicine consultations, delays in DXA scanning, interruptions in the supply of medications and reductions in parenteral medication delivery. Introduction: The COVID-19 pandemic has had profound effects on the health of the global population both directly, via the sequelae of the infection, and indirectly, including the relative neglect of chronic disease management. Together the International Osteoporosis Foundation and National Osteoporosis Foundation sought to ascertain the impact on osteoporosis management. Methods: Questionnaires were electronically circulated to a sample of members of both learned bodies and included information regarding the location and specialty of respondents, current extent of face to face consultations, alterations in osteoporosis risk assessment, telemedicine experience, alterations to medication ascertainment and delivery and electronic health record (EHR) utilisation. Responses were collected, quantitative data analysed, and qualitative data assessed for recurring themes. Results: Responses were received from 209 healthcare workers from 53 countries, including 28% from Europe, 24% from North America, 19% from the Asia Pacific region, 17% from the Middle East and 12% from Latin America. Most respondents were physicians (85%) with physician assistants, physical therapists and nurses/nurse practitioners represented in the sample. The main three specialties represented included rheumatology (40%), endocrinology (22%) and orthopaedics (15%). In terms of the type of patient contact, 33% of respondents conducted telephone consultations and 21% video consultations. Bone mineral density assessment by dual-energy X-ray absorptiometry (DXA) usage was affected with only 29% able to obtain a scan as recommended. The majority of clinicians (60%) had systems in place to identify patients receiving parenteral medication, and 43% of clinicians reported difficulty in arranging appropriate osteoporosis medications during the COVID-19 crisis. Conclusions: To conclude through surveying a global sample of osteoporosis healthcare professionals, we have observed an increase in telemedicine consultations, delays in DXA scanning, interrupted supply of medications and reductions in parenteral medication delivery. © 2021, The Author(s). [less ▲]

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See detailCurrent practice for safe return-to-play after lateral ankle sprain: A survey among French-speaking physicians
Aguilaniu, Aude ULiege; Croisier, Jean-Louis ULiege; Schwartz, Cédric ULiege et al

in Foot and Ankle Surgery (in press)

Background: Recommendations are available for assessment criteria for safe return-to-play (RTP) after a lateral ankle sprain. However, their current use among physicians is unknown. Methods: French ... [more ▼]

Background: Recommendations are available for assessment criteria for safe return-to-play (RTP) after a lateral ankle sprain. However, their current use among physicians is unknown. Methods: French-speaking physicians in Belgium, France and Switzerland were asked to complete an online survey and report their clinical assessment of selected RTP criteria. Results:The respondent sample (n = 109) included physicians with and without Sports Medicine education, varied level of experience and proportion of athletes in their practice population. Pain was the most selected criterion for safe RTP (90% of physicians), followed by ability to engage in functional tasks (82%), functional instability (73%), range of motion (61%), proprioception (47%), mechanical instability (39%), strength (38%) and swelling (31%). A low proportion of physicians use quantitative measures to assess these criteria (between 4% and 53%). Conclusions: A large proportion of physicians consider the recommended criteria for RTP decisions. However, physicians do not frequently use quantitative measures. [less ▲]

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See detailComprehensive analysis of the immunomodulatory effects of rapamycin on human T cells in graft-versus-host disease prophylaxis
Ehx, Grégory ULiege; Ritacco, Caroline ULiege; HANNON, Muriel ULiege et al

in American Journal of Transplantation (in press)

Graft-versus-host disease (GVHD) is a major cause of toxicity after allogeneic hematopoietic cell transplantation (allo-HCT). While rapamycin (RAPA) is commonly used in GVHD prophylaxis in combination ... [more ▼]

Graft-versus-host disease (GVHD) is a major cause of toxicity after allogeneic hematopoietic cell transplantation (allo-HCT). While rapamycin (RAPA) is commonly used in GVHD prophylaxis in combination with a calcineurin inhibitor (CNI), the understanding of its mechanism of action on human T cells is still incomplete. Here, we performed an extensive analysis of RAPA effects on human T cells in a humanized mouse model of GVHD, in ex-vivo T-cell cultures and in patients given RAPA plus tacrolimus as GVHD prophylaxis after non-myeloablative allo-HCT. We demonstrate that RAPA mitigates GVHD by decreasing T-cell engraftment and differentiation, inhibiting CD8+ T-cell activation and increasing the long-term IL-2 secretion, thereby supporting regulatory T-cell (Treg) proliferation. In contrast, graft-versus-leukemia effects were not abrogated, as RAPA-treated T cells had increased resistance to apoptosis and retained their effector function and proliferative capacity upon re-stimulation. Importantly, we found that RAPA impact on Treg and CD8+ T cells was closely dependent upon IL-2 signaling and that therapeutic options interfering with IL-2, such as calcineurin inhibitors, antagonize the IL-2-dependent promotion of Treg mediated by RAPA. Our results suggest that RAPA immunological efficacy could be improved in combination with drugs having possible synergistic effects such as the hypomethylating agent 5-azacytidine. [less ▲]

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See detailInvestigating densities of Symbiodiniaceae in two species of Antipatharians (black corals) from Madagascar
Gress, Erika; Eeckhaut, Igor; Godefroid, Mathilde et al

in Oceans (in press)

Here, we report the first methodological approach to investigate the presence and estimate density of Symbiodiniaceae cells in corals of the order Antipatharia subclass Hexacorallia, known as black corals ... [more ▼]

Here, we report the first methodological approach to investigate the presence and estimate density of Symbiodiniaceae cells in corals of the order Antipatharia subclass Hexacorallia, known as black corals. Antipatharians are understudied ecosystem engineers of shallow (<30 m depth), mesophotic (30-150 m) and deep-sea (>200 m) reefs. They provide habitat to a vast number of marine fauna, enhancing and supporting coral reefs biodiversity globally. Nonetheless, little biological and ecological information exists on antipatharians, including the extent at which global change disturbances are threatening these corals. The assumption that they were exempted from threats related to climate change was challenged by findings of high density of dinoflagellates within three antipatharian colonies. Further methodical studies were necessary to investigate the regularity of these findings. An integrated design combining microscopy and molecular techniques was used to investigate the presence and estimate density of Symbiodiniaceae cells within two antipatharians species - Cupressopathes abies and Stichopathes maldivensis - from shallow and mesophotic reefs of SW Madagascar. Symbiodiniaceae-like cells were found within the two species from both shallow and mesophotic reefs, although the overall cell density was very low (0-4 cell mm-3). These findings suggest that high abundance of Symbiodiniaceae is not characteristic of antipatharians, which has relevant implications considering climate change associated disruptions in other corals. However, the high densities of dinoflagellates found in antipatharian colonies exposed to higher light irradiance in other studies should be further examined. [less ▲]

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See detailVariational interpolation of high-frequency radar surface currents using DIVAnd
Barth, Alexander ULiege; Troupin, Charles ULiege; Emma, Reyes et al

in Ocean Dynamics (in press)

DIVAnd (Data-Interpolating Variational Analysis, in n-dimensions) is a tool to interpolate observations on a regular grid using the variational inverse method. We have extended DIVAnd to include ... [more ▼]

DIVAnd (Data-Interpolating Variational Analysis, in n-dimensions) is a tool to interpolate observations on a regular grid using the variational inverse method. We have extended DIVAnd to include additional dynamic constraints relevant to surface currents, including imposing a zero normal velocity at the coastline, imposing a low horizontal divergence of the surface currents, temporal coherence and simplified dynamics based on the Coriolis force and the possibility of including a surface pressure gradient. The impact of these constraints is evaluated by cross-validation using the HF (High-Frequency) radar surface current observations in the Ibiza Channel from the Balearic Islands Coastal Ocean Observing and Forecasting System (SOCIB). A small fraction of the radial current observations are set aside to validate the velocity reconstruction. The remaining radial currents from the two radar sites are combined to derive total surface currents using DIVAnd and then compared to the cross-validation data set and to drifter observations. The benefit of the dynamic constraints is shown relative to a variational interpolation without these dynamical constraints. The best results were obtained using the Coriolis force and the surface pressure gradient as a constraint which are able to improve the reconstruction from the Open-boundary Modal Analysis, a quite commonly used method to interpolate HF radar observations, once multiple time instances are considered together. [less ▲]

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See detailCompte-rendu de Claude Romano, Être soi-même. Une autre histoire de la philosophie.
Recchia, Fabio ULiege

in Revue Philosophique de Louvain (in press), 2019(4), 746-748

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See detailA Connectivity-Based Psychometric Prediction Framework for Brain-Behavior Relationship Studies.
Wu, Jianxiao; Eickhoff, Simon B.; Hoffstaedter, Felix et al

in Cerebral cortex (New York, N.Y. : 1991) (in press)

The recent availability of population-based studies with neuroimaging and behavioral measurements opens promising perspectives to investigate the relationships between interindividual variability in brain ... [more ▼]

The recent availability of population-based studies with neuroimaging and behavioral measurements opens promising perspectives to investigate the relationships between interindividual variability in brain regions' connectivity and behavioral phenotypes. However, the multivariate nature of connectivity-based prediction model severely limits the insight into brain-behavior patterns for neuroscience. To address this issue, we propose a connectivity-based psychometric prediction framework based on individual regions' connectivity profiles. We first illustrate two main applications: 1) single brain region's predictive power for a range of psychometric variables and 2) single psychometric variable's predictive power variation across brain region. We compare the patterns of brain-behavior provided by these approaches to the brain-behavior relationships from activation approaches. Then, capitalizing on the increased transparency of our approach, we demonstrate how the influence of various data processing and analyses can directly influence the patterns of brain-behavior relationships, as well as the unique insight into brain-behavior relationships offered by this approach. [less ▲]

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See detailFair Long-Term Care Insurance
Pestieau, Pierre ULiege; Leroux, Marie-Louise; Ponthiere, Grégory

in Social Choice and Welfare (in press)

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See detailLe « soi territorial » : propositions théoriques à partir d’une compréhension phénoménologique de la schizophrénie
Englebert, Jérôme ULiege

in Evolution Psychiatrique (in press)

- Objectives This theoretical paper discusses the integration of a 'territorial self' alongside the minimal and narrative selves most commonly described by contemporary phenomenology and used by ... [more ▼]

- Objectives This theoretical paper discusses the integration of a 'territorial self' alongside the minimal and narrative selves most commonly described by contemporary phenomenology and used by phenomenological psychopathology. - Methods We start from the schizophrenic experience and the tools for understanding it to highlight some limitations in the use of vocal communication within the clinical system to evoke phenomena that are a priori pre-linguistic. - Results This theoretical path, which appear necessary to open up to clinical observation and intersubjectivity, leads to nosographic and therapeutic implications which seem useful to us from a phenomenological perspective. - Discussion From a nosographic standpoint, we discuss the (non-systematic) cross-overs between schizophrenic experience and psychotic experience, whereas from a therapeutic standpoint, the proposal of the territorial self allows us to insist on the fact that the clinical relationship is characterised as much by an analysis of the experience and a discussion about it as it is by a joint practice and an experiential experience requiring a shared ground. - Conclusions The theoretical proposal of the "territorial self" proves to be fruitful and heuristic to be able to better understand deepen the nosographic debates in the field of psychosis, and to contribute to a reflection on the practice of psychotherapy. [less ▲]

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See detailQUAND JE S’APPELLE OUBLI : DU SILENCE A L’ADRESSE, UNE POETIQUE DU CHAOS CHEZ LAURENT MAUVIGNIER
Vandormael, Thomas ULiege

in Kwartlanik neofilologiczny (in press)

This study aims to report on how the use of the allocutive person suggested by “Ce que j’appelle oubli”, eighth novel by Laurent Mauvignier, subsume many problematics that preside over the renewal of ... [more ▼]

This study aims to report on how the use of the allocutive person suggested by “Ce que j’appelle oubli”, eighth novel by Laurent Mauvignier, subsume many problematics that preside over the renewal of contemporary fictional forms such as the polyphony of narrative voices, the difficulty of placing an ‘I’ narrator confronted with the writing of society and particularly its minorities, as well as the place of silence within/in the literary text. [less ▲]

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See detailLes abstentions coupables
Jacobs, Ann ULiege; Masset, Adrien ULiege; Lambotte, Patrick ULiege

in Postal Memorialis (in press)

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See detailFormation, diffusion, analyse sémique et analyse distributionnelle des désignations du taureau en Wallonie. Les désignations belgoromanes du taureau sont-elles synonymes ?
Balthazard, Matthieu ULiege

in Dialectes de Wallonie (in press), 37

Cet article s’intègre dans un cadre plus large, celui de la rédaction de la notice TAUREAU de l’Atlas linguistique de la Wallonie, tome 11, consacré au vocabulaire de l’élevage. La notice TAUREAU se ... [more ▼]

Cet article s’intègre dans un cadre plus large, celui de la rédaction de la notice TAUREAU de l’Atlas linguistique de la Wallonie, tome 11, consacré au vocabulaire de l’élevage. La notice TAUREAU se fonde sur les matériaux de quatre questions de l’Enquête de Haust : q. 322 « la semaine prochaine, il faudra mener notre vache au taureau », q. 334 « Le taureau ; entraves qu’on lui met », q. 335 « la vache est en chaleur » (dans le contexte : ⸀désire le taureau⸣) et q. 336 « faire saillir la vache par le taureau ». La grande carte et une première version du tableau des formes ont été préparées par Marie-Thérèse Counet. Notre analyse poursuit trois objectifs. Elle vise dans un premier temps à identifier les types lexicaux relevés dans les quatre questions, à en retracer l’histoire (formation et diffusion spatiale) et, par voie de conséquence, à les ordonner dans le temps. Dans un deuxième temps, notre analyse cherche à déterminer finement les significations des types, par l’analyse de leurs contextes d’occurrence. En troisième lieu, notre analyse cherche à identifier les relations entre ces types et donc à répondre à la question suivante : ces types sont-ils des synonymes ?, des géosynonymes ? Se pencher sur ces questions mène subséquemment à une autre interrogation, à savoir celle de la délimitation (au moins partielle) de la notion de synonymie quand elle est envisagée dans le cadre de la géolinguistique. [less ▲]

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See detailAmbrogio e Agostino: spazi e pratiche battesimali a Milano e in Nord Africa a confronto
Neri, Elisabetta ULiege

in Studia Ambrosiana (in press), 13

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See detailEffect of chronic intracerebroventricular administration of an aromatase inhibitor on the expression of social sexual behaviors in male Japanese quail.
Court, Lucas ULiege; Balthazart, Jacques ULiege; Ball, Gregory F et al

in Behavioural Brain Research (in press)

Aromatase converts androgens into estrogens in the brain of vertebrates including humans. This enzyme is also expressed in other tissues where its action may result in negative effects on human health (e ... [more ▼]

Aromatase converts androgens into estrogens in the brain of vertebrates including humans. This enzyme is also expressed in other tissues where its action may result in negative effects on human health (e.g., promotion of tumor growth). To prevent these effects, aromatase inhibitors were developed and are currently used to block human estrogen-dependent tumors. In vertebrates including quail, aromatase is expressed in a highly conserved set of interconnected brain nuclei known as the social behavior network. This network is directly implicated in the expression of a large range of social behaviors. The primary goal of this study was to characterize in Japanese quail the potential impact of brain aromatase on sexual behavior, aggressiveness and social motivation (i.e., tendency to approach and stay close to conspecifics). An additional goal was to test the feasibility and effectiveness of long-term delivery of an aromatase inhibitor directly into the third ventricle via Alzet™ osmotic minipumps using male sexual behavior as the aromatase dependent measure. We demonstrate that this mode of administration results in the strongest inhibition of both copulatory behavior and sexual motivation ever observed in this species, while other social behaviors were variably affected. Sexual motivation and the tendency to approach a group of conspecifics including females clearly seem to depend on brain aromatase, but the effects of central estrogen production on aggressive behavior and on the motivation to approach males remain less clear. [less ▲]

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See detailA model of the optimal allocation of government expenditures
Pestieau, Pierre ULiege; Fan, Simon; Pang, Yu

in Journal of Public Economic Theory (in press)

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See detailThe Famennian flora of Barraba, New South Wales, Australia.
Meyer-Berthaux; Decombeix, A.L.; Girard, C. et al

in Review of Palaeobotany and Palynology (in press)

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See detailSlices of the past: how events are temporally compressed in episodic memory
D'Argembeau, Arnaud ULiege; Jeunehomme, Olivier ULiege; Stawarczyk, David ULiege

in Memory (in press)

Remembering everyday events typically takes less time than the actual duration of the retrieved episodes, a phenomenon that has been referred to as the temporal compression of events in episodic memory ... [more ▼]

Remembering everyday events typically takes less time than the actual duration of the retrieved episodes, a phenomenon that has been referred to as the temporal compression of events in episodic memory. Here, we review recent studies that have shed light on how this compression mechanism operates. The evidence suggests that the continuous flow of experience is not represented as such in episodic memory. Instead, the unfolding of events is recalled as a succession of moments or slices of past experience that includes temporal discontinuities—portions of past experience are omitted when remembering. Consequently, the rate of event compression is not constant but depends on the density of recalled segments of past experience. [less ▲]

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See detailHippocampus co-atrophy pattern in dementia deviates from covariance patterns across the lifespan.
Plachti, Anna; Kharabian, Shahrzad; Eickhoff, Simon B. et al

in Brain : a journal of neurology (in press)

The hippocampus is a plastic region and highly susceptible to ageing and dementia. Previous studies explicitly imposed a priori models of hippocampus when investigating ageing and dementia-specific ... [more ▼]

The hippocampus is a plastic region and highly susceptible to ageing and dementia. Previous studies explicitly imposed a priori models of hippocampus when investigating ageing and dementia-specific atrophy but led to inconsistent results. Consequently, the basic question of whether macrostructural changes follow a cytoarchitectonic or functional organization across the adult lifespan and in age-related neurodegenerative disease remained open. The aim of this cross-sectional study was to identify the spatial pattern of hippocampus differentiation based on structural covariance with a data-driven approach across structural MRI data of large cohorts (n = 2594). We examined the pattern of structural covariance of hippocampus voxels in young, middle-aged, elderly, mild cognitive impairment and dementia disease samples by applying a clustering algorithm revealing differentiation in structural covariance within the hippocampus. In all the healthy and in the mild cognitive impaired participants, the hippocampus was robustly divided into anterior, lateral and medial subregions reminiscent of cytoarchitectonic division. In contrast, in dementia patients, the pattern of subdivision was closer to known functional differentiation into an anterior, body and tail subregions. These results not only contribute to a better understanding of co-plasticity and co-atrophy in the hippocampus across the lifespan and in dementia, but also provide robust data-driven spatial representations (i.e. maps) for structural studies. [less ▲]

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See detailAn individualised approach for a one-abutment one-time protocol using full guided surgery: a 4-year follow-up case series
VINCENT, Kim ULiege; LI MANNI, Lou; Mainjot, Amélie ULiege et al

in International Journal of Computerized Dentistry (in press)

Aim: The aim of this case series was to evaluate the 4-year outcomes of implants placed in the aesthetic area using static computer-assisted implant surgery (s-CAIS) and restored with a one-abutment one ... [more ▼]

Aim: The aim of this case series was to evaluate the 4-year outcomes of implants placed in the aesthetic area using static computer-assisted implant surgery (s-CAIS) and restored with a one-abutment one-time (OAOT) protocol using custom-made zirconia abutments and cemented provisional crowns manufactured prior to surgery. Material and methods: Ten consecutive implants were placed in the aesthetic area. Based on a digital implant and prosthodontic planning, surgical guides were ordered and used for the preparation of definitive custom-made zirconia abutments and polymethylmethacrylate provisional crowns. Implants were placed using the s-CAIS guide, and prosthetic components were placed immediately. Implant outcomes were evaluated at the time of surgery, after 4 months and after 4 years. Results: All implants were successfully placed with s-CAIS and restored with final abutments and provisional crowns. No major prosthetic adverse events were observed. After 4 years, the implant survival rate was 100%, minor peri-implant bleeding on probing was reported, and very stable peri-implant bone levels were observed. The pink aesthetic score showed that the prosthetic components were well integrated, and the peri-implant soft tissues were stable. Conclusions: Within the limits of this case series, these results suggest that emerging digital workflows allow the manufacture of final custom-made abutments and provisional crowns prior to surgery. This individualised OAOT procedure may reduce cement-related complications and improve aesthetic outcomes by optimising soft tissue healing with prosthetic components. However, such protocols have evolved towards full digital workflows, and comparative clinical trials are needed. [less ▲]

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See detailImmediate implant in the posterior region combined with alveolar ridge preservation and Sealing Socket Abutment: A retrospective 3D radiographic Analysis
Alexopoulou, Marianzela; LAMBERT, France ULiege; Knafo, Bryan et al

in Clinical Implant Dentistry and Related Research (in press)

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See detailSwallowing in individuals with disorders of consciousness: A cohort study
MELOTTE, Evelyne ULiege; MAUDOUX, Audrey ULiege; DELHALLE, Sabrina ULiege et al

in Annals of Physical and Rehabilitation Medicine (in press)

Background. After a period of coma, a proportion of individuals with severe brain injury remain in an altered state of consciousness before regaining partial or complete recovery. Individuals with ... [more ▼]

Background. After a period of coma, a proportion of individuals with severe brain injury remain in an altered state of consciousness before regaining partial or complete recovery. Individuals with disorders of consciousness (DOC) classically receive hydration and nutrition through an enteral feeding tube. However, the real impact of the level of consciousness on an individual’s swallowing ability remains poorly investigated. Objective. We aimed to document the incidence and characteristics of dysphagia in DOC individuals and to evaluate the link between different components of swallowing and the level of consciousness. Methods. We analyzed clinical data on the respiratory status, oral feeding and otolaryngologic examination of swallowing in DOC individuals. Univariate and multivariate logistic regression was used to analyse the association of components of swallowing and participant groups (i.e., unresponsive wakefulness syndrome [UWS] and minimally conscious state [MCS]). Results. We included 92 individuals with DOC (26 UWS and 66 MCS). Overall, 99% of the participants showed deficits in the oral and/or pharyngeal phase of swallowing. As compared with the MCS group, the UWS group more frequently had a tracheostomy (69% vs 24%), with diminished cough reflex (27% vs 54%) and no effective oral phase (0% vs 21%). Conclusion. Almost all DOC participants had severe dysphagia. Some components of swallowing (i.e., tracheostomy, cough reflex and efficacy of the oral phase of swallowing) were related to consciousness. In particular, no UWS participant had an efficient oral phase, which suggests that its presence may be a sign of consciousness. In addition, no UWS participant could be fed entirely orally, whereas no MCS participant orally received ordinary food. Our study also confirms that objective swallowing assessment can be successfully completed in DOC individuals and that specific care is needed to treat severe dysphagia in DOC. [less ▲]

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See detailOn the length of monotone paths in polyhedra
Blanchard, Moise; De Loera, Jesus; Louveaux, Quentin ULiege

in SIAM Journal on Discrete Mathematics (in press)

Motivated by the problem of bounding the number of iterations of the Simplex algorithm we investigate the possible lengths of monotone paths followed inside the oriented graphs of polyhedra (oriented by ... [more ▼]

Motivated by the problem of bounding the number of iterations of the Simplex algorithm we investigate the possible lengths of monotone paths followed inside the oriented graphs of polyhedra (oriented by the objective function). We consider both the shortest and the longest monotone paths and estimate the monotone diameter and height of polyhedra. Our analysis applies to transportation polytopes, matroid polytopes, matching polytopes, shortest-path polytopes, and the TSP, among others. We begin by showing that combinatorial cubes have monotone diameter and Bland simplex height upper bounded by their dimension and that in fact all monotone paths of zonotopes are no larger than the number of edge directions of the zonotope. We later use this to show that several polytopes have polynomial-size monotone diameter. In contrast, we show that for many well-known combinatorial polytopes, the height is at least exponential. Surprisingly, for some famous pivot rules, e.g., greatest improvement and steepest edge, these same polytopes have polynomial-size simplex paths. [less ▲]

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See detailCovid-19: contribution of clinical characteristics and laboratory features for early detection of patients with high risk of severe evolution
Sepulchre, Edith; Pittie, Guillaume; Stojkovic, Violeta et al

in Acta Clinica Belgica (in press)

The aim of this study was to identify early clinical and laboratory predictive factors of a severe coronavirus disease 2019 (COVID-19). The study revealed clinical and laboratory features able to predict ... [more ▼]

The aim of this study was to identify early clinical and laboratory predictive factors of a severe coronavirus disease 2019 (COVID-19). The study revealed clinical and laboratory features able to predict high risk of ICU requirement, or even death, at admission time. These results provide a potential tool for patient’s triage in a context of pandemic. [less ▲]

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See detailPrediction of 5-year mortality risk by malnutrition according to the GLIM format using seven pragmatic approaches to define the criterion of loss of muscle mass
Sanchez Rodriguez, Maria Dolores Carmen ULiege; Locquet, Médéa ULiege; Bruyère, Olivier ULiege et al

in Clinical Nutrition (in press)

Objectives: To assess the association between baseline malnutrition according to the GLIM format, using seven pragmatic approaches to define the criterion of loss of muscle mass, with mortality in the ... [more ▼]

Objectives: To assess the association between baseline malnutrition according to the GLIM format, using seven pragmatic approaches to define the criterion of loss of muscle mass, with mortality in the SarcoPhAge (Sarcopenia and Physical Impairment with advancing Age) study during a 5-year follow-up. Secondarily, to calculate diagnostic performance indicators, concordance, and feasibility of these 7 pragmatic approaches compared to the original GLIM criteria. Methods: Post-hoc analysis of the SarcoPhAge cohort, which included 534 community-dwelling volunteers ≥ 65-year-old, followed-up from 2013 to 2019. Baseline malnutrition was defined by GLIM criteria and 7 approaches: 1) Omission of a reduced muscle mass as a criterion; 2) Substitution for handgrip strength, 3) Calf-circumference, 4) Mid-arm circumference, 5) Goodman's grid, 6) Ishii's score chart, and 7) Yu's formula. The association between malnutrition (according to GLIM criteria and the 7 approaches) and mortality was assessed by Cox-regressions. Sensitivity, Specificity, Positive (PPV), Negative (NPV) predictive values, area under the curve (AUC), Cohenekappa coefficient, and TELOS-feasibility score were calculated. Results: Data to calculate GLIM criteria were available for 373 subjects (73.07 ± 5.96 years, 56% women). Prevalence of malnutrition with GLIM criteria was 24.4% (ranged from 13.9% to 20.9% with the 7 approaches). GLIM criteria showed a HR ¼ 3.38 (1.89-6.09) to predict mortality during the 5-year follow-up which ranged from HR = 2.72 (1.51 - 4.91) to 3.94 (2.14 - 7.24) with the 7 approaches. All 7 approaches were feasible (TELOS ≥ 3), showed sensitivity ≥ 65%, specificity ≥ 95.4%, PPV ≥ 85%, NPV ≥ 88%, AUC ≥ 0.7 and had almost-perfect/strong concordance (k ≥ 0.7) with the original GLIM criteria. Conclusions: GLIM criteria and the 7 approaches predicted three-to four-fold mortality, all ensured an accurate diagnosis, and were feasible in clinical settings. [less ▲]

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See detailFurther observations on the spores of the Rhynie chert plant Horneophyton lignieri (Kidston & Lang) Barghoorn & Darrah, 1938: Implications for paleodiversity studies
Casales-Minana, B.; Servais, T.; Capel, E. et al

in Review of Palaeobotany and Palynology (in press)

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See detail"Cooperative game” inspired approach for multi-area power system: day ahead – intraday markets & security management taking advantage of grid flexibilities
Karangelos, Efthymios ULiege; Panciatici, Patrick

in Philosophical Transactions of the Royal Society of London. Series A, Containing Papers of a Mathematical or Physical Character (in press)

This paper advocates for a progressive rethinking of the day-ahead/intra-day power system security management practice in the low-carbon energy transition era. As a starting point, the need for multi-TSO ... [more ▼]

This paper advocates for a progressive rethinking of the day-ahead/intra-day power system security management practice in the low-carbon energy transition era. As a starting point, the need for multi-TSO coordination in order to efficiently exploit the value of grid flexibility towards operating the low-carbon, multi-area power system securely and economically is established. On this basis, the core proposal of this paper is the adoption of a new approach to day-ahead/intra-day multi-area power system security management, inspired from the principles of cooperative game theory. The proposed approach relies on counterfactual analysis to evaluate the (positive and/or negative) impact of each distinctive control-area to the common security of the multi-area system, thus providing clear economic incentives to achieve the required coordination. This proposal is not a marginal approach and notably facilitates the integration of more detailed physical modeling (including the non-convexities of the power system) in the inter-TSO settlement of the multi-area interconnected system security management cost. The proposed framework allows some level of subsidiarity and the definition of hedging products to cover ex-post costs. Further from the blueprint of the proposed approach, the paper discusses prominent research and development pathways in order to progressively put such vision into practice. [less ▲]

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