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See detailR en 30 minutes
Ligot, Gauthier ULiege

Learning material (2011)

R basics

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See detailR&D, Capital Structure, and Agency Conflict: A Contingent Claim Analysis
Tiwari, Amaresh Kumar ULiege

E-print/Working paper (2013)

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See detailR&D, technological progress and efficiency change in industrial activities
Perelman, Sergio ULiege

in Review of Income and Wealth (1995), (41), 349-366

The objective of this paper is to estimate total factor productivity growth (TFP) in an international and sectoral setting using two alternative approaches based on the estimation of parametric stochastic ... [more ▼]

The objective of this paper is to estimate total factor productivity growth (TFP) in an international and sectoral setting using two alternative approaches based on the estimation of parametric stochastic frontiers and non-parametric production frontiers (DEA). The TFP is decomposed into two components, technological progress and efficiency change, that can also be interpreted as the results of the innovation and catching-up process, respectively. Finally their relationship is tested with a set of potential explanatory variables that includes R&D expenditures, international competition, and structural characteristics. It appears that the distinction between technological and efficiency performances does matter and must be taken into account in the design of industrial policy. [less ▲]

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See detail(R)-4-phenyloxazolidin-2-thione: an efficient chiral auxiliary for [4+2] cycloaddition of 1-aminodienes and activated phosphonodienophiles
Monbaliu, Jean-Christophe ULiege; Robiette, Raphaël; Peeters, Daniel et al

in Tetrahedron Letters (2009), 50

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See detail(R)évolutions dans la gestion des eaux de surface
Dewals, Benjamin ULiege

Scientific conference (2012, January 23)

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See detailR-HuEPO hyporesponsiveness - who and why ?
Danielson, B.; Beguin, Yves ULiege; Bommer, J. et al

in Nephrology Dialysis Transplantation (1995), 10

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See detailR-parity violating sneutrino decays
Aristizabal Sierra, Diego ULiege; Hirsch, M.; Porod, W.

in Journal of High Energy Physics [=JHEP] (2005), 0509

R-parity can be violated through either bilinear and/or trilinear terms in the superpotential. The decay properties of sneutrinos can be used to obtain information about the relative importance of these ... [more ▼]

R-parity can be violated through either bilinear and/or trilinear terms in the superpotential. The decay properties of sneutrinos can be used to obtain information about the relative importance of these couplings provided sneutrinos are the lightest supersymmetric particles. We show that in some specific scenarios it is even possible to decide whether bilinear or trilinear terms give the dominant contribution to the neutrino mass matrix. [less ▲]

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See detailR. Clausius, sa vie, ses travaux et leur portée métaphysique
Folie, François ULiege

in Revue des Questions Scientifiques (1890), 27

François Folie drafts Rudolf Clausius's biography as well as an analysis and comments on his various works.

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See detailR. H. Carr, Plutarch's Lives of Coriolanus, Caesar, Brutus and Antonius in North's translation
Hamélius, Paul ULiege

in Revue de l'Instruction Publique en Belgique (1907), 50

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See detailR. Hunter, Critical Moments in Classical Literature. Studies in the Ancient View of Literature and Its Uses, Cambridge, University PRESS, 2009.
Caneva, Stefano ULiege

in Athenaeum : Studii Periodici di Letteratura e Storia (2012), 100. I-II

Detailed reference viewed: 25 (1 ULiège)
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See detailR. M. Rilke en de Nederlandse kritiek
de Landsheere, Gilbert ULiege

in Vlaamse Gids (De) (1950), 34

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See detailR. Sacré, « Les Negro Spirituals et les Gospel Songs »
Pirenne, Christophe ULiege

in Cahiers de Clio (1994), 119

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See detailR. Sacré, « Musiques Cajun, Créole et Zydeco »
Pirenne, Christophe ULiege

in Revue de la Société liégeoise de Musicologie (1996), 4

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See detailR.P.D.B. Tome XI, Complément : Pourvoi en cassation en matière civile
Boularbah, Hakim ULiege; Gerard, P; van Drooghenbroeck, J.-F.

in P.P.D.B., Tome XI (2011)

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See detail(R/S)-3-(3-Methyl-2-butylamino)-4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxide mono-hydrate
Dupont, L.; De Tullio, Pascal ULiege; Tinant, B. et al

in Acta Crystallographica (2001), E57

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See detailR164H and V240H replacements by site-directed mutagenesis of TEM-149 extended-spectrum beta-lactamase: kinetic analysis of TEM-149H240 and TEM-149H164-H240 laboratory mutants.
Perilli, Mariagrazia; Celenza, Giuseppe; Mercuri, Paola ULiege et al

in Antimicrobial agents and chemotherapy (2013), 57(2), 1047-9

Two laboratory mutant forms, TEM-149(H240) and TEM-149(H164-H240), of the TEM-149 extended-spectrum beta-lactamase enzyme were constructed by site-directed mutagenesis. TEM-149(H240) and TEM-149(H164-H240 ... [more ▼]

Two laboratory mutant forms, TEM-149(H240) and TEM-149(H164-H240), of the TEM-149 extended-spectrum beta-lactamase enzyme were constructed by site-directed mutagenesis. TEM-149(H240) and TEM-149(H164-H240) were similar in kinetic behavior, except with respect to benzylpenicillin and ceftazidime. Molecular modeling of the two mutant enzymes demonstrated the role of histidine at position 240 in the reduction of the affinity of the enzyme for ceftazidime. [less ▲]

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See detailThe R304X mutation of the Aryl hydrocarbon receptor Interacting Protein gene in familial isolated pituitary adenomas: mutational Hot-Spot or founder effect?
Occhi, G.; Jaffrain-Rea, M. L.; Trivellin, G. et al

in Journal of Endocrinological Investigation (2010), 33

Background: Mutations in the Aryl hydrocarbon receptor Interacting Protein (AIP) gene have been described in about 15% of kindreds with Familial Isolated Pituitary Adenomas (FIPA) and in a minority of ... [more ▼]

Background: Mutations in the Aryl hydrocarbon receptor Interacting Protein (AIP) gene have been described in about 15% of kindreds with Familial Isolated Pituitary Adenomas (FIPA) and in a minority of early onset sporadic pituitary adenomas (PA). Among the AIP mutations reported so far, the R304X (AIPR304X) represents, together with the "Finnish mutation" Q14X, the most common one. Methods: Three AIPR304X Italian families, including a newly reported kindred, have been genotyped for 12 genetic markers surrounding the AIP gene in order to look for a potential founder effect in Italy. Disease penetrance and genotype-phenotype correlations were also addressed. Results: Analysis of chromosome 11' genetic markers revealed a common haplotype in two AIPR304X kindreds originating from central Italy. Overall, seventeen mutations carriers were identified, including 7 patients and 10 unaffected subjects, respectively, arguing in this case for a disease penetrance of 41%. Mean age at diagnosis was 19.1+/-6.7 years-old, with females tending to be older than males. Though most PA were somatotropinomas (6/7), a great variability in disease severity was observed, even between subjects sharing the same at-risk haplotype. Conclusion: These data provide strong evidence for a new founder effect of the AIPR304X mutation in central Italy and the observed variations in disease severity point out the role of additional genetic or environmental factors in such kindreds. [less ▲]

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See detailRab guanine nucleotide exchange factor 1 (Rabgef1) restricts intestinal inflammation by limiting pro-inflammatory signals in Intestinal Epithelial Cells (IECs)
El Abbas, Sophie ULiege; Beguin, Charline ULiege; Schyns, Joey ULiege et al

in Proceedings: 4th FARAH-DAY (2017, October 13)

Rab guanine nucleotide exchange factor (GEF-)1 (Rabgef1), a multifunctional protein whose in vivo functions remained unknown until recently, is highly expressed in mouse and human epithelial cells. The ... [more ▼]

Rab guanine nucleotide exchange factor (GEF-)1 (Rabgef1), a multifunctional protein whose in vivo functions remained unknown until recently, is highly expressed in mouse and human epithelial cells. The aim of this study is to investigate the role of Rabgef1 in intestinal epithelial cells (IECs) and intestinal homeostasis in mice. We performed conditional deletion of Rabgef1 gene using the cre-lox system to obtain mice lacking Rabgef1 specifically in IECs (Rabgef1IEC-KO), under the wild-type (WT) or the colitis-prone Interleukin-10 (Il-10)-deficient background. In addition, we used the CRISPR-Cas9 technology to obtain a murine IEC line deficient in Rabgef1. Rabgef1IEC-KO mice under the WT background did not develop spontaneous intestinal abnormalities but exhibited an altered intestinal microbial composition associated with minor changes in IEC pro-inflammatory gene expression profile. Moreover, Rabgef1IEC-KO mice exhibited an increased susceptibility to inflammation in a dextran sodium sulfate (DSS)-induced model of colitis under the WT background, as well as in a constitutive model of colitis under the Il-10-¬deficient background. In vitro, we showed that mouse IECs lacking Rabgef1 significantly overexpressed several pro-inflammatory cytokines and chemokines as compared to control cells. Taken together, these results support that Rabgef1 acts as a regulator of intestinal homeostasis and inflammation, and that dysregulated Rabgef1 expression could contribute to intestinal barrier dysfunction in inflammatory conditions of the gut. [less ▲]

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