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See detailExploring Jupiter: JUNO
Bonfond, Bertrand ULiege

Scientific conference (2015, September 15)

A short overview of the NASA Juno mission and its results, plus a quick presentation of the STAR contribution to the ESA JUICE mission.

Detailed reference viewed: 32 (9 ULiège)
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See detailExploring limiting factors in the prediction of allogeneic HSCT related mortality: an in-silico machine learning analysis of the acute leukemia working party (ALWP) registry of the EBMT
SHOUVAL, R.; LABOPIN, M.; UNGER, R. et al

in Bone Marrow Transplantation (2015, March), 50

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See detailExploring Metacognition as Support for Learning Transfer
Scharff, Lauren; Draeger, John; Verpoorten, Dominique ULiege et al

in Teaching & Learning Inquiry: The ISSoTL Journal (2017), 5(1),

The ability to transfer learning to new situations lies at the heart of lifelong learning and the employability of university graduates. Because students are often unaware of the importance of learning ... [more ▼]

The ability to transfer learning to new situations lies at the heart of lifelong learning and the employability of university graduates. Because students are often unaware of the importance of learning transfer and staff do not always explicitly articulate this expectation, this article explores the idea that metacognition (intentional awareness and the use of that awareness) might enhance the development of learning transfer. Our exploratory study includes results from a survey of 74 staff and 118 students from five institutions in Australia, Belgium, UK, and USA. Our data indicate that many staff and a majority of students do not have a clear understanding of what learning transfer entails, and that there are many mismatches between staff and student perceptions, attitudes, and behaviors regarding learning transfer. This helps explain why learning transfer does not occur as often as it could. We found significant positive correlations between thinking about transfer and thinking about learning processes and the likelihood to use awareness of metacognition to guide practice. Our findings suggest a positive relationship between metacognition and learning transfer. Implications for scholarship of teaching and learning are discussed. [less ▲]

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See detailExploring Metacognition as Support for Learning Transfer
Devlin, Marie; Draeger, John; Dvorakova, Lucie Sam et al

Conference (2016, October 14)

This presentation will share our efforts to investigate how metacognition might enhance the transfer of learning from one context to another. This topic is of relevance because the ability to transfer ... [more ▼]

This presentation will share our efforts to investigate how metacognition might enhance the transfer of learning from one context to another. This topic is of relevance because the ability to transfer one’s learning to new situations lies at the heart of lifelong learning and the employability of university graduates. [less ▲]

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See detailExploring molecular antipodes with flow chemistry
Monbaliu, Jean-Christophe ULiege

in Monbaliu, Jean-Christophe (Ed.) FROST 6 (2017)

This lecture illustrates our work in flow chemistry with chemicals at the antipodes of molecular complexity. The first example deals with the valorization of biomass-derived small platform molecules, and ... [more ▼]

This lecture illustrates our work in flow chemistry with chemicals at the antipodes of molecular complexity. The first example deals with the valorization of biomass-derived small platform molecules, and in particular the implementation of a deoxydehydration (DODH) reaction of glycerol towards allyl alcohol under continuous-flow conditions. The combination of a unique reactive dynamic feed solution approach and short exposure to high temperature gave high yield and excellent selectivity in the presence of formic acid, triethyl orthoformate, or a combination of both. The second example deals with the preparation of large bio macromolecules, and in particular the implementation of chemical native ligation towards peptide constructs under continuous-flow conditions. The combination of the unique assets of microfluidic reactors and the development of new reagents/conditions were exploited to perform extremely fast ligations at difficult junctions that are notoriously time-consuming. Ligation times down to 2 min were achieved, with excellent conversion and overall isolated yields for a range of macrocylic peptides bearing up to 29 residues. The reaction conditions were also amenable, upon minor adjustments, to less hindered junctions. [less ▲]

Detailed reference viewed: 48 (4 ULiège)
See detailExploring needs and applicability of a 3D urban land register information system
Billen, Roland ULiege

Scientific conference (2008, April 24)

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See detailExploring New Achievements in olefin metathesis catalysts. Part 1 - Highlights on N-heterocyclic carbene ruthenium complexes
Dragutan, Valerian; Dragutan, Ileana; Delaude, Lionel ULiege et al

in Chimica Oggi = Chemistry Today (2009), 27(3), 9-12

Most important advances in ruthenium catalysts for olefin metathesis achieved during the last 4 years are briefly reviewed. The first part of the survey focuses on new catalytic precursors endowed with ... [more ▼]

Most important advances in ruthenium catalysts for olefin metathesis achieved during the last 4 years are briefly reviewed. The first part of the survey focuses on new catalytic precursors endowed with inventive N-heterocyclic carbene ligands which have proved highly proficient in a diversity of applications based on metathesis reactions. Part two extends the progress in other types of Ru initiators. [less ▲]

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See detailExploring new achievements in olefin metathesis catalysts. Part 2 - Compelling innovations in ruthenium complexes
Dragutan, Ileana; Dragutan, Valerian; Delaude, Lionel ULiege et al

in Chimica Oggi = Chemistry Today (2009), 27(3), 13-16

This part of the survey introduces recent developments on de novo designed types of ruthenium complexes used as promoters in olefin metathesis reactions. Encompassing diversity-oriented initiators not ... [more ▼]

This part of the survey introduces recent developments on de novo designed types of ruthenium complexes used as promoters in olefin metathesis reactions. Encompassing diversity-oriented initiators not illustrated in Part 1, in this second part of the review emphasis is placed on the leading role played by distinct ligands in an exquisite control of metathesis reactions. [less ▲]

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See detailExploring new dimensions in cadaveric decomposition odour analysis
Stefanuto, Pierre-Hugues ULiege; Perrault, Katelynn; Lloyd, Rebecca et al

in Analytical Methods (2015), 7

This study demonstrates the first documented use of comprehensive two-dimensional gas chromatography – high-resolution time-of-flight mass spectrometry (GC×GC-HRTOFMS) for volatile organic compound ... [more ▼]

This study demonstrates the first documented use of comprehensive two-dimensional gas chromatography – high-resolution time-of-flight mass spectrometry (GC×GC-HRTOFMS) for volatile organic compound analysis in the forensic sciences. High-resolution mass spectral data provided higher confidence in analyte identification. GC×GC-HRTOFMS will be valuable for future studies of decomposition odour and other complex volatile matrices. [less ▲]

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See detailExploring new dimensions in cadaveric decomposition odour profiling using GC×GC-HRTOFMS
Perrault, Katelynn ULiege; Stefanuto, Pierre-Hugues ULiege; Lloyd, R et al

Conference (2015, September)

Detailed reference viewed: 7 (3 ULiège)
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See detailExploring PNS in Fabry disease
WANG, François-Charles ULiege; BOUQUIAUX, Olivier ULiege

Scientific conference (2013, November 19)

Detailed reference viewed: 15 (4 ULiège)
Peer Reviewed
See detailExploring possibilities through imagination. What can be conceived and what can be seen
Leclercq, Bruno ULiege

Conference (2017, September 29)

Detailed reference viewed: 17 (0 ULiège)
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See detailExploring potentialities of RanbP2-type Zinc Fingers in RNA-binding proteins design
De Franco, Simona ULiege; Vandenameele, Julie ULiege; Galleni, Moreno ULiege et al

Poster (2016, June 29)

Transcriptomes consist of several classes of RNAs, whose roles are central to innumerable biological processes as well as diseases. These observations justify the increasing interest in the engineering of ... [more ▼]

Transcriptomes consist of several classes of RNAs, whose roles are central to innumerable biological processes as well as diseases. These observations justify the increasing interest in the engineering of functionalized RNA-binding proteins (RBPs) to specifically manipulate RNA function. In this context, the RanBP2-type Zinc Finger (ZF) domain emerged as a suitable scaffold for single-stranded RBPs design. The present study aimed to identify the sequence-specificity of several naturally occurring RanBP2-type ZFs by in vitro selection and use the natural variation in their substrate to create arrays of ZF domains displaying customized specificity. A parallel kinetic and thermodynamic characterization of ssRNA-ZFs interaction was performed by Isothermal Titration Calorimetry (ITC) and BioLayer Interferometry (BLI), respectively. Although our data showed that only little variations in the recognized sequence could be observed for the studied ZFs, they contribute to elucidate the molecular basis for the RanBP2-type ZF-ssRNA interaction. [less ▲]

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See detailExploring self-defining memories in schizophrenia.
Raffard, Stephane; D'Argembeau, Arnaud ULiege; Lardi, Claudia et al

in Memory (2009), 17(1), 26-38

Previous studies have shown that patients with schizophrenia are impaired in recalling specific events from their personal past. However, the relationship between autobiographical memory impairments and ... [more ▼]

Previous studies have shown that patients with schizophrenia are impaired in recalling specific events from their personal past. However, the relationship between autobiographical memory impairments and disturbance of the sense of identity in schizophrenia has not been investigated in detail. In this study the authors investigated schizophrenic patients' ability to recall self-defining memories; that is, memories that play an important role in building and maintaining the self-concept. Results showed that patients recalled as many specific self-defining memories as healthy participants. However, patients with schizophrenia exhibited an abnormal reminiscence bump and reported different types of thematic content (i.e., they recalled less memories about past achievements and more memories regarding hospitalisation and stigmatisation of illness). Furthermore, the findings suggest that impairments in extracting meaning from personal memories could represent a core disturbance of autobiographical memory in patients with schizophrenia. [less ▲]

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See detailExploring sex differences in the adult zebra finch brain: in vivo diffusion tensor imaging and ex vivo super-resolution track density imaging
Hamaide, J.; De Groof, G.; Van Steenkiste, G. et al

in NeuroImage (2017), 146

Zebra finches are an excellent model to study the process of vocal learning, a complex socially-learned tool of communication that forms the basis of spoken human language. So far, structural ... [more ▼]

Zebra finches are an excellent model to study the process of vocal learning, a complex socially-learned tool of communication that forms the basis of spoken human language. So far, structural investigation of the zebra finch brain has been performed ex vivo using invasive methods such as histology. These methods are highly specific, however, they strongly interfere with performing whole-brain analyses and exclude longitudinal studies aimed at establishing causal correlations between neuroplastic events and specific behavioral performances. Therefore, the aim of the current study was to implement an in vivo Diffusion Tensor Imaging (DTI) protocol sensitive enough to detect structural sex differences in the adult zebra finch brain. Voxel-wise comparison of male and female DTI parameter maps shows clear differences in several components of the song control system (i.e. Area X surroundings, the high vocal center (HVC) and the lateral magnocellular nucleus of the anterior nidopallium (LMAN)), which corroborate previous findings and are in line with the clear behavioral difference as only males sing. Furthermore, to obtain additional insights into the 3-dimensional organization of the zebra finch brain and clarify findings obtained by the in vivo study, ex vivo DTI data of the male and female brain were acquired as well, using a recently established super-resolution reconstruction (SRR) imaging strategy. Interestingly, the SRR-DTI approach led to a marked reduction in acquisition time without interfering with the (spatial and angular) resolution and SNR which enabled to acquire a data set characterized by a 78μm isotropic resolution including 90 diffusion gradient directions within 44h of scanning time. Based on the reconstructed SRR-DTI maps, whole brain probabilistic Track Density Imaging (TDI) was performed for the purpose of super resolved track density imaging, further pushing the resolution up to 40μm isotropic. The DTI and TDI maps realized atlas-quality anatomical maps that enable a clear delineation of most components of the song control and auditory systems. In conclusion, this study paves the way for longitudinal in vivo and high-resolution ex vivo experiments aimed at disentangling [less ▲]

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See detailExploring Structure and Reformulations in Different Integer Programming Algorithms
Louveaux, Quentin ULiege

Doctoral thesis (2004)

In this thesis we consider four topics all related to using problem reformulations in order to solve integer programs, i.e. optimization problems in which the decision variables must be integer. We first ... [more ▼]

In this thesis we consider four topics all related to using problem reformulations in order to solve integer programs, i.e. optimization problems in which the decision variables must be integer. We first consider the polyhedral approach. We start by addressing the ques- tion of lifting valid inequalities, i.e. finding a valid inequality for a set Y from the knowledge of a valid inequality for a lower-dimensional restriction X of Y . We simplify and clarify the presentation of the procedure. This allows us to derive conditions under which the computation of the lifting is tractable. The second topic is the study of valid inequalities for the single node flow set. The single node flow set is the problem obtained by considering one node of a fixed charge network flow problem. We derive valid inequalities for this set and various generalizations. Our approach is a systematic procedure using only basic tools of integer programming: fixing and complementing variables, mixed- integer rounding and lifting. The method allows us to explain and generate a large range of inequalities describing the convex hull of such sets. The last two topics are based on non-standard approaches for integer pro- gramming. We first show how the group relaxation approach can be used to provide reformulations for the integral basis method. This is based on a study of extended formulations for the group problem. We present four extended for- mulations and show that the projections of three of these formulations provide the convex hull of the original group problem. Initial computational tests of the approach are also reported. Finally we consider a problem that is difficult for the standard branch-and- bound approach even for small instances. A reformulation based on lattice basis reduction is known to be more effective. However the step to compute the re- duced basis is O(n4) and becomes a bottleneck for small to medium instances. By using the structure of the problem, we show that we can decompose the problem and obtain the basis by taking the kronecker product of two smaller bases easier to compute. Furthermore, if the two small bases are reduced, the kronecker product is also reduced up to a reordering of the vectors. Computa- tional results show the gain from such an approach. [less ▲]

Detailed reference viewed: 64 (2 ULiège)