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See detailLa colibacillose aviaire
Stordeur, Philippe; Mainil, Jacques ULiege

in Annales de Médecine Vétérinaire (2002), 146(1, FEB-MAR), 11-18

The avian pathogenic E. coli strains, although considered by almost like opportunist pathogen, represent actually one of the most important cause of economic losses in the poultry sector and is one of the ... [more ▼]

The avian pathogenic E. coli strains, although considered by almost like opportunist pathogen, represent actually one of the most important cause of economic losses in the poultry sector and is one of the most frequent cause of carcase rejection in the slaughter house. Colibacillosis, which the major way of penetration is the respiratory tract, affect essentially broilers and give variable lesions and manifestations in function of the age of the animals. Actually, some virulence factors have been studied and associated with avian pathogenic E. coli strains : P and F1 fimbriae, hemagglutination, serum resistance, aerobactin system. Recent studies have also showed that other virulence factors (F17 and Afa adhesins) were also present in the avian pathogenic E. coli, but their rule in the pathogenicity must to be established. Because of the diversity of virulence factors and the little of knowledge about us, no vaccine is actually available to protect efficacely poultries against colibacillosis. Thus, the antibiotherapy based on a good diagnostic and a good prevention remained the only things to do in order to overcome the disease, despite the augmentation of antibiotics resistance and the risk of transferring to humans. [less ▲]

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See detailLes colibacillose dans l'espèce bovine.
Mainil, Jacques ULiege

Conference (1993)

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See detailLes colibacilloses dans l'espèce bovine
Mainil, Jacques ULiege

in Annales de Médecine Vétérinaire (1993), 137

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See detailColibacillosis in newborn calves : link between classical bacteriology and molecular biology
Mainil, Jacques ULiege

Scientific conference (1992, October)

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See detailColin Stetson : l'indie rock
Levaux, Christophe ULiege

Article for general public (2014)

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See detailColite aigue revelant une maladie de Wegener
Lebas, Eglantine ULiege; Gielen, Sabine ULiege; Nguyen, Minh Ngoc ULiege et al

in Revue Médicale de Liège (2006), 61(3), 163-8

We report the case of a 52 year old man who was hospitalized within a context of a persistent deterioration of his general condition. He was suspected of having a chronic inflammatory colitis. A pulmonary ... [more ▼]

We report the case of a 52 year old man who was hospitalized within a context of a persistent deterioration of his general condition. He was suspected of having a chronic inflammatory colitis. A pulmonary radiography revealed the presence of voluminous bilateral excavated masses with hydro-aerical levels. After having refuted among others a suspicion of tuberculosis, the results of a thoracic percutaneous transpleural lung aspiration by needle under tomodensitometric control steered our diagnosis towards a vascularitis of the Wegener disease type. A treatment with corticotherapy in large doses completed with cyclophosphamid allowed for clinical, biological and radiological improvement. Wegener's granulomatosis usually starts in an insidious manner with febrile episodes and an impairment of the general condition associated with inflammatory biological signs, as observed in our patient. After these warning symptoms, come ORL and/or pulmonary and/or renal impairment, which represent the classical triad of diffused GW. However a certain number of particularities unusual for that diagnosis characterized our patient and prompted the discussion of this case. [less ▲]

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See detailA colitogenic memory CD4+ T cell population mediates gastrointestinal graft-versus-host disease.
Zhou, Vivian; Agle, Kimberle; Chen, Xiao et al

in Journal of Clinical Investigation (2016), 126(9), 3541-55

Damage to the gastrointestinal tract is a major cause of morbidity and mortality in graft-versus-host disease (GVHD) and is attributable to T cell-mediated inflammation. In this work, we identified a ... [more ▼]

Damage to the gastrointestinal tract is a major cause of morbidity and mortality in graft-versus-host disease (GVHD) and is attributable to T cell-mediated inflammation. In this work, we identified a unique CD4+ T cell population that constitutively expresses the beta2 integrin CD11c and displays a biased central memory phenotype and memory T cell transcriptional profile, innate-like properties, and increased expression of the gut-homing molecules alpha4beta7 and CCR9. Using several complementary murine GVHD models, we determined that adoptive transfer and early accumulation of beta2 integrin-expressing CD4+ T cells in the gastrointestinal tract initiated Th1-mediated proinflammatory cytokine production, augmented pathological damage in the colon, and increased mortality. The pathogenic effect of this CD4+ T cell population critically depended on coexpression of the IL-23 receptor, which was required for maximal inflammatory effects. Non-Foxp3-expressing CD4+ T cells produced IL-10, which regulated colonic inflammation and attenuated lethality in the absence of functional CD4+Foxp3+ T cells. Thus, the coordinate expression of CD11c and the IL-23 receptor defines an IL-10-regulated, colitogenic memory CD4+ T cell subset that is poised to initiate inflammation when there is loss of tolerance and breakdown of mucosal barriers. [less ▲]

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See detailColl2-1 and Coll2-1 NO2: markers of early disease in the Hartley guinea pig model of spontaneous OA
Huebner, JL; DEBERG, Michelle ULiege; Henrotin, Yves ULiege et al

in Osteoarthritis and Cartilage (2007), 15(Suppl C), 70

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See detailColl2-1 peptide and its nitrated form as therapeutic targets for osteoarthritis treatment
Henrotin, Yves ULiege; Lambert, Cécile ULiege; Borderie, Didier et al

Patent (2016)

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See detailColl2-1, Coll2-1 NO2 and myeloperoxidase in OA patients before and after hip or knee replacement
Deberg, M; Labasse, A; Quettier, E et al

Conference (2006)

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See detailColl2-1, Coll2-1 NO2 and myeloperoxidase serum levels in erosive and non-erosive osteoarthritis of the hands
Ramonda, R; DEBERG, Michelle ULiege; Campana, C et al

in Osteoarthritis and Cartilage (2008), 16(Suppl 4), 56

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See detailColl2-1, Coll2-1 NO2 and myeloperoxydase in OA patients before and after hip or knee replacement
Deberg, M; Labasse, A; Quettier, E et al

in Osteoporosis International (2006)

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See detailColl2-1, Coll2-1NO2 and myeloperoxidase concentrations in the synovial fluid of equine tarsocrural joints affected with osteochondrosis.
Verwilghen, Denis ULiege; Martens, Ann; Busschers, Evita et al

in Veterinary Research Communications (2011), 35(7), 401-8

The measurement of biomarkers that reflect cartilage breakdown is a powerful tool for investigating joint damage caused by disease or injury. Particularly in cases of osteochondrosis, synovial ... [more ▼]

The measurement of biomarkers that reflect cartilage breakdown is a powerful tool for investigating joint damage caused by disease or injury. Particularly in cases of osteochondrosis, synovial concentrations of these biomarkers may reveal the presence of osteoarthritic changes. Coll2-1, Coll2-1 NO2 and myeloperoxidase have recently been introduced in equine osteoarticular research but comparison between the concentrations of these markers in OCD affected and healthy joints has not been made. Therefore, this study aimed at reporting the synovial concentrations of these biomarkers in joints affected with osteochondral fragments in the tarsocrural joint compared to unaffected joints. Myeloperoxidase and Coll2-1NO2 revealed to have similar levels between affected joints and controls. However, in contrast to previous studies using C2C the present study demonstrated that synovial levels of Coll2-1 were significantly elevated in tarsocrural joints affected with osteochondrosis. Thus, Coll2-1 may be an earlier marker of cartilage degeneration than other cartilage degradation markers that have been previously used in equine medicine. [less ▲]

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See detailColl2-1, Coll2-1NO2 and myeloperoxidase serum levels in erosive and non-erosive osteoarthritis of the hands.
Punzi, L.; Ramonda, R.; DEBERG, Michelle ULiege et al

in Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society (2012), 20(6), 557-61

OBJECTIVE: Erosive osteoarthritis of the hand (EHOA) is thought to be an aggressive variant of hand osteoarthritis (HOA) characterised by prominent local inflammation and radiographic aspects of bone ... [more ▼]

OBJECTIVE: Erosive osteoarthritis of the hand (EHOA) is thought to be an aggressive variant of hand osteoarthritis (HOA) characterised by prominent local inflammation and radiographic aspects of bone erosions in interphalangeal (IP) joints. However, rare studies have until now investigated the value of biomarkers in these patients. Thus, we determined Coll2-1, a marker of type II collagen denaturation, its nitrated form (Coll2-1NO2) and myeloperoxidase (MPO) levels in serum of patients with EHOA vs non-EHOA and subsequently evaluated their relationships with disease indices of severity and activity. METHODS: Coll2-1, Coll2-1NO2 and MPO were measured using specific immunoassays in 82 patients, 57 with EHOA, all females, median age 59 (41-74 yrs) and 20 with non-EHOA, all females, median age 55 (43-73 yrs), fulfilling the American College of Rheumatology (ACR) criteria for hand OA. EHOA was characterized by the presence of at least one central bone erosion on radiograph in the IP joints. Patients were also evaluated for disease duration, number of affected (swollen and painful or tender) joints, radiographic score (RS) by Kallman scale and high sensitivity C-reactive protein (hsCRP). RESULTS: Serum levels of MPO were higher in EHOA (230.0 +/- 152.1 ng/ml) than in non-EHOA (160.2 +/- 111.5 ng/ml, P=0.037). Coll2-1NO2 levels trended towards an elevation in EHOA compared non-EHOA (0.40 +/- 0.86 vs 0.22 +/- 0.14 nmol/l, P=0.06), while Coll2-1 levels were not different. Correlations were found for disease duration and both MPO (R(2)=0.48, P=0.001) and Coll2-1NO2 (R(2)=0.73, P=0.01) after the splitting of the population in subgroups according to a cut off value above the 50th percentile. A correlation was found between hsCRP and MPO (R(2)=0.57, P=0.01). CONCLUSIONS: This study clearly demonstrates an elevation of some serum biomarkers in EHOA, in comparison with non-EHOA. In particular, MPO, hsCRP and the ratio Coll2-1NO2/Coll2-1 discriminated the two subsets of hand osteoarthritis (HOA), and a trend was also observed for Coll2-1NO2. These data suggest that these biomarkers could be helpful for the diagnosis of EHOA. [less ▲]

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See detailCollaboration autour de la construction d’une séquence d’éveil scientifique et développement professionnel
Poffé, Corentin ULiege; Hindryckx, Marie-Noëlle ULiege

Poster (2015)

Comment contribuer au développement professionnel de futurs enseignants en mettant en place une collaboration entre deux institutions de formations des maitres, en sciences.

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See detailLa collaboration entre architectes et plasticiens à Liège dans les années 1930.
Charlier, Sébastien ULiege

in In Situ : Revue des Patrimoines (2017), 32(2017),

En 1928, des étudiants de l’Académie des Beaux-Arts de Liège fondent la revue d’architecture et d’urbanisme L’Équerre. S’inscrivant bien que tardivement dans la continuité des avant-gardes internationales ... [more ▼]

En 1928, des étudiants de l’Académie des Beaux-Arts de Liège fondent la revue d’architecture et d’urbanisme L’Équerre. S’inscrivant bien que tardivement dans la continuité des avant-gardes internationales, le mensuel revendique une vision transversale de l’architecture où la réflexion plastique occupe une place centrale. Dès le départ, elle s’associe à Anthologie, revue imprégnée des théories futuristes et qui diffuse les artistes de l’avant-garde locale. D’abord par le biais de l’édition et des expositions, plasticiens et architectes travaillent ensuite ensemble dans le cadre de projets ambitieux financés par les pouvoirs publics. Cette contribution revient aux racines de cette collaboration en définissant les liens théoriques ou personnels unissant les deux revues. En se concentrant sur les infrastructures publiques, elle comment les artistes et les architectes ont répondu ensemble aux exigences concrètes de la commande en les replaçant dans le contexte social, politique et économique d’une ville belge de seconde importance à la veille de la Seconde Guerre mondiale. [less ▲]

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See detailLa collaboration entre différentes disciplines médicales : ou est le problème ? Etude Partnership in Medicine
Vanmeerbeek, Marc ULiege; Govers, Patrick ULiege; Schippers, Nathalie ULiege et al

Conference (2015, March 27)

Objectifs Les maladies ou problèmes médicaux d’origine professionnelle, ou en lien avec le travail, impliquent à des degrés divers les médecins généralistes (MG), les médecins du travail (MT) et les ... [more ▼]

Objectifs Les maladies ou problèmes médicaux d’origine professionnelle, ou en lien avec le travail, impliquent à des degrés divers les médecins généralistes (MG), les médecins du travail (MT) et les médecins-conseils des mutuelles (MC). Le manque de relation fonctionnelle entre eux peut compliquer ou retarder le retour au travail du patient. L’étude cherchait des pistes d’amélioration de la collaboration. Méthode Deux méthodes de consensus ont été successivement utilisées parmi les trois professions : huit groupes nominaux (GN) ont réunis 74 médecins de terrain; deux rondes Delphi ont concerné 28 décideurs. Résultats Un seul médecin a été perdu de vue entre les 2 tours du Delphi. Les propositions issues des GN concernaient le transfert d’informations (surtout les MT et les MC), la collaboration (surtout les MG et les MT), les connaissances, et le cadre légal et réglementaire (surtout les MC). Cinq questions sur 14 n’ont pas fait consensus (≥75%) au 1er tour du Delphi, et 10 propositions sur 13 ont été rejetées au 2e tour. Les désaccords portaient sur la nature des données à transférer, les modalités de transfert d’information, la disponibilité des données de contact des médecins. Un processus d’évitement spécifique a été mis en évidence. Certains commentaires montraient un déni de la capacité des autres à comprendre son champ professionnel, et une difficulté à considérer leur spécificité propre. Conclusions L’étude montre que le patient n’est pas un objet partagé de la relation. Le modèle Resource Dependence Institutional Cooperation (De Rijk) permet de distinguer les entraves à la volonté de coopérer (dépendance perçue) des limitations dans la capacité à le faire (manque de ressources). Le modèle quadridimensionnel de la collaboration (D’Amour) identifie un déficit d’internalisation du côté relationnel (reconnaissance des autres), et un déficit de gouvernance et de formalisation du côté organisationnel, où des initiatives volontaristes des autorités seraient bienvenues. [less ▲]

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See detailLa collaboration entre les CPAS et autres institutions d'Aide Sociale
Gavray, Claire ULiege; Huvelle, P.

in Observatoire : Revue d'Action Sociale & Médico-Sociale (1993), 1-2

Detailed reference viewed: 51 (2 ULiège)