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See detailCardiovascular Responses to Static Assessments of Trunk Muscles
Demoulin, Christophe ULiege; Grosdent, Stéphanie ULiege; Bury, Thierry ULiege et al

in Journal of Musculoskeletal Pain (2009), 17(4), 378-389

Objectives: To investigate the cardiovascular responses to standard static assessments of strength and endurance of trunk extensor muscles. Methods: Trunk extensor performances of ten healthy men, 48.2±5 ... [more ▼]

Objectives: To investigate the cardiovascular responses to standard static assessments of strength and endurance of trunk extensor muscles. Methods: Trunk extensor performances of ten healthy men, 48.2±5.6 years, and 10 healthy women, 49±5.7 years, were assessed by means of a maximum static strength test [consisting in maximal voluntary contractions [MVC] performed with a specific dynamometer], and two static endurance tests [the Sorensen test, and a 50 percent MVC test]. Heart rate [HR], auscultatory systolic [SBP], and diastolic blood pressure [DBP] were recorded throughout the tests. Results: The MVCs induced significant increases of HR and SBP [mean peak values averaging 90 [female] to 95 [male] beats per minute and 133 [female] to 141 [male] mmHg]. The HR, SBP, and DBP values increased significantly across time throughout both endurance static tests. At the end of these tests, mean HR, SBP, and DBP reached 114 to 122 beats per minute, 172 to 185 mmHg, and 112 to 120 mmHg. Genders differed significantly with regard to holding times [longer in females], but a gender effect was only found on SBP [higher in males]. Heart rate and SBP increases were significantly higher in males than in female subjects. Conclusions: The strength test seems less demanding than expected, though our results need to be confirmed. Standard static endurance tests yield sizeable functional stress on the cardiovascular system. Our study emphasizes the need to exclude subjects with cardiac trouble from such efforts and suggests the relevance of monitoring cardiovascular parameters if tests are performed until exhaustion. [less ▲]

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See detailCardiovascular risk factor pattern in children. Results from a population study. "The Belgian Luxembourg Child Study".
Guillaume, Michèle ULiege; Lapidus, L.; Beckers, F. et al

in Prog XV International Diabetes Epidemiology Group meeting (1993)

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See detailCardiovascular risk factors and complications associated with albuminuria and impaired renal function in insulin-treated diabetes.
Doggen, Kris; Nobels, Frank; SCHEEN, André ULiege et al

in Journal of Diabetes & its Complications (2013)

AIMS: To establish the association between albuminuria and cardiovascular risk factors as well as micro- and macrovascular complications in type 1 and insulin-treated type 2 diabetes, both in the presence ... [more ▼]

AIMS: To establish the association between albuminuria and cardiovascular risk factors as well as micro- and macrovascular complications in type 1 and insulin-treated type 2 diabetes, both in the presence and in the absence of reduced estimated glomerular filtration rate (eGFR). METHODS: Cross-sectional study including 7640 insulin-treated diabetic patients (33% type 1) treated in specialist diabetes centers. Albuminuria was defined as >/=30mg/g, 20mg/L, 20mug/min or 30mg/24h. Reduced eGFR was defined as <60mL/min/1.73m2 (CKD-EPI equations). RESULTS: Albuminuria, reduced eGFR or a combination was more prevalent in type 2 (21.5%, 15.9% and 16.5%) than in type 1 diabetes (16.1%, 4.7% and 4.0%, all P<0.001 vs. type 2). Albuminuria was associated with poorer control of blood pressure, blood lipids and glycemia as well as higher prevalence of retinopathy and macrovascular disease, regardless of preserved/reduced eGFR or diabetes type. Reduced eGFR was associated with higher prevalence of micro- and macrovascular complications especially in type 2 diabetes. Combined presence of albuminuria and reduced eGFR was associated with the worst cardiovascular outcomes. CONCLUSIONS: Albuminuria and impaired renal function are prevalent in type 1 and insulin-treated type 2 diabetes. Albuminuria, but also normoalbuminuric renal impairment, is associated with micro- and macrovascular complications. [less ▲]

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See detailCardiovascular risk factors and complications associated with impaired renal function and albuminuria in insulin-treated type 2 diabetes
Doggen, K.; SCHEEN, André ULiege; Van Crombrugge, P. et al

in Diabetologia (2011)

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See detailCardiovascular risk factors in children from the Belgian province of Luxembourg. The Belgian Luxembourg Child Study.
Guillaume, Michèle ULiege; Lapidus, L.; Beckers, L. et al

in American Journal of Epidemiology (1996), 144(9), 867-80

The Province of Luxembourg is an area in Belgium with a high prevalence of risk factors for cardiovascular disease and non-insulin-dependent diabetes mellitus among adults. In the present study, children ... [more ▼]

The Province of Luxembourg is an area in Belgium with a high prevalence of risk factors for cardiovascular disease and non-insulin-dependent diabetes mellitus among adults. In the present study, children in the age groups 6-8, 8-10, and 10-12 years were selected at random from school classes (n = 1,028), with a participation rate of 70.3%. Anthropometric factors, blood pressure, and fasting blood glucose, plasma cholesterol, triglyceride, and insulin levels were measured in 1992. All anthropometric and metabolic variables increased with age, except for waist: hip circumference ratio in boys and cholesterol in girls. In the oldest group, girls who had passed menarche were taller and heavier and had greater skinfold, body mass index, insulin, and systolic blood pressure values but lower total cholesterol levels and waist: hip ratios than girls who had not passed menarche. Boys had lower skinfolds and higher waist: hip ratios than girls in all age groups, and were significantly shorter and lighter in the oldest age group. There was no difference in body mass index between the two sexes. Girls had higher triglyceride and insulin levels in the 10- to 12-year age group, lower blood glucose values in the 8-10 and 10-12 age groups, and lower diastolic blood pressures in the 8-10 age group. Obesity, blood glucose, triglycerides, insulin, and blood pressure were highly interrelated. Cholesterol, triglycerides, insulin, and blood pressure values were all among the highest of values previously reported in other studies. The deciles of body mass index above 50 appeared to be particularly elevated, suggesting that obesity, when present, was pronounced in this population of children. These findings suggest an accumulation of genetic susceptibility to cardiovascular disease and non-insulin-dependent diabetes mellitus in this stable, ethnically homogeneous, and rather isolated part of continental Europe. [less ▲]

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See detailCardiovascular risk-benefit profile of sibutramine.
Scheen, André ULiege

in American Journal of Cardiovascular Drugs : Drugs, Devices, & Other Interventions (2010), 10(5), 321-34

Sibutramine is a combined norepinephrine and serotonin reuptake inhibitor used as an antiobesity agent to reduce appetite and promote weight loss in combination with diet and exercise. At a daily dose of ... [more ▼]

Sibutramine is a combined norepinephrine and serotonin reuptake inhibitor used as an antiobesity agent to reduce appetite and promote weight loss in combination with diet and exercise. At a daily dose of 10-20 mg, it was initially considered to have a good safety profile, as it does not induce primary pulmonary hypertension or adverse effects on cardiac valves, in contrast to previous reports relating to some other antiobesity agents. However, it exerts disparate effects on cardiovascular risk factors. On the one hand, sibutramine may have antiatherogenic activities, as it improves insulin resistance, glucose metabolism, dyslipidemia, and inflammatory markers, with most of these effects resulting from weight loss rather than from an intrinsic effect of the drug. On the other hand, because of its specific mode of action, sibutramine exerts a peripheral sympathomimetic effect, which induces a moderate increase in heart rate and attenuates the reduction in BP attributable to weight loss or even slightly increases BP. It may also prolong the QT interval, an effect that could induce arrhythmias. Because of these complex effects, it is difficult to conclude what the final impact of sibutramine on cardiovascular outcomes might be. Sibutramine has been shown to exert favorable effects on some surrogate cardiovascular endpoints such as reduction of left ventricular hypertrophy and improvement of endothelial dysfunction. A good cardiovascular safety profile was demonstrated in numerous 1- to 2-year controlled trials, in both diabetic and nondiabetic well selected patients, as well as in several observational studies. However, since 2002, several cardiovascular adverse events (hypertension, tachycardia, arrhythmias, and myocardial infarction) have been reported in sibutramine-treated patients. This led to a contraindication of the use of this antiobesity agent in patients with established coronary heart disease, previous stroke, heart failure, or cardiac arrhythmias. SCOUT (Sibutramine Cardiovascular and Diabetes Outcome Study) was designed to prospectively evaluate the efficacy/safety ratio of sibutramine in a high-risk population. The efficacy/safety results of the first 6-week lead-in open period of treatment with sibutramine 10 mg/day were reassuring in 10 742 overweight/obese high-risk subjects (97% had cardiovascular disease, 88% had hypertension, and 84% had type 2 diabetes mellitus). However, the final results of SCOUT showed that long-term (5 years') treatment with sibutramine (10-15 mg/day) exposed subjects with pre-existing cardiovascular disease to a significantly increased risk for nonfatal myocardial infarction and nonfatal stroke, but not cardiovascular death or all-cause mortality. Because the benefit of sibutramine as a weight-loss aid seems not to outweigh the cardiovascular risks, the European Medicines Agency recommended the suspension of marketing authorizations for sibutramine across the EU. The US FDA stated that the drug should carry a 'black box' warning due to an increased risk of stroke and heart attack in patients with a history of cardiovascular disease. In conclusion, concern still persists about the safety profile of sibutramine regarding cardiovascular outcomes, and the drug should not be prescribed for overweight/obese patients with a high cardiovascular risk profile. [less ▲]

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See detailCardiovascular safety of albiglutide and other glucagon-like peptide-1 receptor agonists.
Scheen, Andre ULiege

in The lancet. Diabetes & endocrinology (2015), 3(9), 667-9

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See detailCardiovascular safety of strontium ranelate: real-life assessment in clinical practice.
Donneau, Anne-Françoise ULiege; Reginster, Jean-Yves ULiege

in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2014), 25

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See detailCare and Conflict: Transnational Practices within Moroccan Family Networks
Zickgraf, Caroline ULiege

Conference (2013, April)

Detailed reference viewed: 18 (1 ULiège)
See detailLe care dans l’accompagnement professionnel de curriculum
Pirard, Florence ULiege

Scientific conference (2012, January 27)

Detailed reference viewed: 21 (4 ULiège)
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See detailCare delivery and outcomes among Belgian children and adolescents with type 1 diabetes.
Doggen, K.; Debacker, N.; Beckers, D. et al

in European Journal of Pediatrics (2012), 171(11), 1679-85

We aimed to investigate care processes and outcomes among children and adolescents with type 1 diabetes treated in hospital-based multidisciplinary paediatric diabetes centres. Our retrospective cross ... [more ▼]

We aimed to investigate care processes and outcomes among children and adolescents with type 1 diabetes treated in hospital-based multidisciplinary paediatric diabetes centres. Our retrospective cross-sectional study among 12 Belgian centres included data from 974 patients with type 1 diabetes, aged 0-18 years. Questionnaires were used to collect data on demographic and clinical characteristics, as well as process of care completion and outcomes of care in 2008. Most patients lived with both biological or adoption parents (77 %) and had at least one parent of Belgian origin (78 %). Nearly all patients (>/=95 %) underwent determination of HbA(1c) and BMI. Screening for retinopathy (55 %) and microalbuminuria (73 %) was less frequent, but rates increased with age and diabetes duration. Median HbA(1c) was 61 mmol/mol (7.7 %) [interquartile range 54-68 mmol/mol (7.1-8.4 %)] and increased with age and insulin dose. HbA(1c) was higher among patients on insulin pump therapy. Median HbA(1c) significantly differed between centres [from 56 mmol/mol (7.3 %) to 66 mmol/mol (8.2 %)]. Incidence of severe hypoglycaemia was 30 per 100 patient-years. Admissions for ketoacidosis had a rate of 3.2 per 100 patient-years. Patients not living with both biological or adoption parents had higher HbA(1c) and more admissions for ketoacidosis. Parents' country of origin was not associated with processes and outcomes of care. Conclusion: Outcomes of care ranked well compared to other European countries, while complication screening rates were intermediate. The observed centre variation in HbA(1c) remained unexplained. Outcomes were associated with family structure, highlighting the continuing need for strategies to cope with this emerging challenge. [less ▲]

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See detailCare of the Self, Denial of the World
Delhalle, Nancy ULiege

in Stalpaert, Christel (Ed.) No beauty for me there where human life is rare : On Jan Lauwers’ theatre work with Needcompany (2007)

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See detailCareer development for international researchers
Halleux, Isabelle ULiege

Diverse speeche and writing (2016)

This talk as invited speaker aims to express how and why the stakeholders opinions converge on the competences required from researchers and the needs for their career assessment. Inspiring tools and very ... [more ▼]

This talk as invited speaker aims to express how and why the stakeholders opinions converge on the competences required from researchers and the needs for their career assessment. Inspiring tools and very good practices exist that be shared to help employers as well as the researchers themselves. [less ▲]

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See detailCareer end for teachers: Towards a better understanding of stress and early retirement
Hansez, Isabelle ULiege; Bertrand, Françoise ULiege; De Keyser, Véronique ULiege et al

in Travail Humain (Le) (2005), 68(3), 193-223

An increasing number of teachers decide to resign before legal retirement age, leading to significant shortages within the profession. A survey was conducted among teachers working in the city of Liege ... [more ▼]

An increasing number of teachers decide to resign before legal retirement age, leading to significant shortages within the profession. A survey was conducted among teachers working in the city of Liege, Belgium. This aimed to determine what led them to withdraw from their jobs and the degree to which stress contributed to their decisions. Various adjustments were made in favour of elderly workers, such as working time and training. The question of whether these are sufficient to keep them motivated in their job was raised. A questionnaire was developed to try and identify the reasons why teachers resign, their motivations for staying in the job and their expectations in terms of career-end adjustments. The key concepts included in this tool were personal factors, job-related factors (i.e. working conditions, organizational and structural changes and job recognition) and employment-related factors. This questionnaire was combined with a subjective stress measure (MSP-A, Lemyre [less ▲]

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See detailCareer patterns and legislative behaviour in multilevel systems
Dodeigne, Jérémy ULiege

Conference (2016, April 15)

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See detailCareer Patterns in Multi-level Quebec and Wallonia: Towards a Sub-State and Federal Political Class?
Dodeigne, Jérémy ULiege

in Reuchamps, Min (Ed.) Minority Nations in Multinational Federations: A comparative study of Quebec and Wallonia (2015)

The process of regionalisation in Western Europe has renewed the interest in political careers, not only for newly regionalised unitary states but also for established federations (Stolz 2003). Recently ... [more ▼]

The process of regionalisation in Western Europe has renewed the interest in political careers, not only for newly regionalised unitary states but also for established federations (Stolz 2003). Recently, Docherty (2011: 186) rightly stated that “there has been little analytical work on the Canadian political career ” . And, arguably, even less on political careers in Quebec. Though, since the end of the 1990s, Walloon political careers have received greater attention (Fiers 2001a, 2001b; Pilet, Fiers and Steyvers 2007; Vanlangenakker, Maddens and Put 2010). Based on an original dataset, this chapter proposes a comprehensive analyses of federal and regional careers since the 1990s in Quebec and in Wallonia. More specifically, it presents and explains the circulation of members of parliament (MPs) in the two federations, with a specific focus on career maintenance at a single level of government (professional political careers) and career advancement (level-hopping movements between political arenas). [less ▲]

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See detailCareer Patterns in Multi-level Systems. A Survival Analysis of Political Careers in Catalonia, Quebec, Scotland, and Wallonia.
Dodeigne, Jérémy ULiege

Conference (2013, September 05)

With the process of regionalisation in formerly unitary democracies, there is a renewed interest for conceptual and empirical studies on political careers. Not only in new federal political systems, but ... [more ▼]

With the process of regionalisation in formerly unitary democracies, there is a renewed interest for conceptual and empirical studies on political careers. Not only in new federal political systems, but also in established federations. Yet, critical questions remain unsolved on both methodological and empirical aspects. This proposal seeks to provide original answers based on a comparative analysis of four regions from established and new federal systems: Catalonia in Spain, Quebec in Canada, Scotland in the UK and Wallonia in Belgium. The paper proceeds in two stages. From a methodological view, even though current research analyse individual trajectories, they do not take individual careers but predominantly inter-territorial movements as the unit of analysis. This paper demonstrates that an individual approach – following every single trajectory over time and across territories – is a better unit of analysis to uncover all career patterns. Based on a “survival analysis” of 2.443 careers, a quantitative analysis tests several hypotheses to explain the variations in career patterns across regions. Two covariates of interest are more particularly tested: the effect of former regional/national experience on political career; the differences of survival rates at the regional and national levels between regionalist and national parties. [less ▲]

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See detailLa carence en vitamine d chez les femmes enceintes en region liegeoise: un probleme meconnu.
Cavalier, Etienne ULiege; Delanaye, Pierre ULiege; Morreale, Alessandro et al

in Revue Médicale de Liège (2008), 63(2), 87-91

We have evaluated the prevalence of the 25-hydroxy vitamin D (25VTD) deficiency in recently pregnant women and new mothers in the area of Liege, Belgium. The study took place in November 2006. Twenty four ... [more ▼]

We have evaluated the prevalence of the 25-hydroxy vitamin D (25VTD) deficiency in recently pregnant women and new mothers in the area of Liege, Belgium. The study took place in November 2006. Twenty four women who underwent a positive pregnancy test and 65 new mothers were enrolled. The level of 25VTD did not differ between the two groups. Only 12% of the pregnant women and 14% of the new mothers (>12 ng/ml) had an optimal level of 25VTD (>30 ng/ ml). We also observed a severe 25VTD deficiency in 21% of pregnant women and 32% of new mothers. Our results showed that more than 80% of pregnant women and new mothers in the area of Liege presented a deficiency in 25VTD. In Belgium, daily vitamin supplementation of pregnant women is common, but the level of vitamin D3 concentration range from 10 microg (400 UI) to zero microg. In our area, vitamin D production in the skin is not always important enough to achieve optimal levels. Our data show that vitamin D supplementation of pregnant women is not enough and that 25VTD deficiency is not diagnosed in this high-risk population. Children born from deficient mothers will present a higher risk of suffering from bone mineral diseases as well as other pathologies, as type 1 diabetes or neurological disorders. Of course, this insufficiency will also have an impact on mother's bone reserve, but these mothers will also be at higher risk for preeclampsia. [less ▲]

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See detailcarence en vitamine D dans la population belge: Un vrai problème de santé publique?
Cavalier, Etienne ULiege; Bouüaert, Corine ULiege

Conference given outside the academic context (2007)

Detailed reference viewed: 164 (6 ULiège)