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See detailL'essor des thérapies ciblées en oncologie pédiatrique
DRESSE, Marie-Françoise ULiege; DAVID, BA; DEMARCHE, M. et al

in Revue Médicale de Liège (in press)

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See detailAnalyse médico-légale du profil socio-économique de victimes féminines de violences conjugales en région liégeoise selon la gravité des blessures subies
Clessens, Audrey ULiege; Partoune, Aurélien ULiege; Garcet, Serge ULiege et al

in Revue Médicale de Liège (2021), 76e année

Objectives : The aim of this study was to ana- lyse retrospectively the profile of female victims of intimate partner violence (IPV) within the population of victims of assault and battery seen in ... [more ▼]

Objectives : The aim of this study was to ana- lyse retrospectively the profile of female victims of intimate partner violence (IPV) within the population of victims of assault and battery seen in expertise at the Forensic Ins- titute of Liège. Method : Overall, 678 files were analysed. The proportion, nature and type of IPV were determined, as well as the profile of the victims. The link between the socio-economic profile and the seriousness of the sequelae was analysed on the basis of the Chi-square test. Results : 8,4 % of the files concerned IPV, of which 93,0 % were female victims. All the victims had suffered physical domes- tic violence and 55,5 % of the victims cumulated at least two forms of violence. According to Johnson’s typology, 56,6 % of IPV cases may be considered as «Situational Couple Violence» and 43,4 % as «Intimate Terrorism». We have not demonstrated a link between the socio-economic profile and the severity of the sequelae. Conclusion : There are differences between the profile of victims of IPV accor- ding to the literature and the profile of victims seen at the IML. Subject to these differences, we have not found a link between the socio-economic status and the severity of the sequelae of IPV victims. [less ▲]

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See detailUn nouveau traitement de l’alopécie androgéno-génétique : les injections dans le cuir chevelu de plasma riche en plaquettes (PRP) autologue
MOREAU, Thomas; CASTRONOVO, Charlotte ULiege; Kaux, Jean-François ULiege et al

in Revue Médicale de Liège (2021), 76(2), 117-121

Androgenic alopecia is a genetically determined and leads to a progressive hair loss of the vertex, affecting both men and women. It is related to an important psychological and social distress. Medical ... [more ▼]

Androgenic alopecia is a genetically determined and leads to a progressive hair loss of the vertex, affecting both men and women. It is related to an important psychological and social distress. Medical therapies include topical minoxidil, oral 5α-reductase inhibitors and oestroprogestative drugs with anti-androgen effects for women. The surgical option is autograft hair transplantation. Recently, phototherapy with low-level energy lasers became available. All these treatments may present adverse effects and their effectiveness is questionable. Subcutaneous injections of autologous platelet-rich plasma into the scalp represent an interesting alternative treatment for androgenetic alopecia, as monotherapy or as an adjuvant treatment. The methodology, the possible mechanisms of action and some initial clinical results of this treatment are presented. [less ▲]

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See detailLe diabète de type 2 et les polluants chimiques de l'environnement à effet perturbateur endocrinien
Claessens, Julien ULiege; CHARLIER, Corinne ULiege

in Revue Médicale de Liège (2021), 76(2), 105-110

Les perturbateurs endocriniens sont des produits chimiques ou molécules naturelles capables d'interférer avec le système hormonal des organismes vivants. Ces polluants peuvent entraîner l'apparition de ... [more ▼]

Les perturbateurs endocriniens sont des produits chimiques ou molécules naturelles capables d'interférer avec le système hormonal des organismes vivants. Ces polluants peuvent entraîner l'apparition de pathologies endocriniennes chez l'Homme ou chez l'animal. Dans publication, nous envisagerons le rôle possible de certaines familles de produits chimiques perturbateurs endocriniens sur l'apparition du diabète de type 2, pathologie dont la prévalence est en forte augmentation au niveau mondial. [less ▲]

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See detailCollecte de données épidémiologiques sur la santé bucco-dentaire chez des jeunes enfants dans le cadre des consultations O.N.E. en Province de Liège - Étude pilote conduite auprès de 212 enfants dans 11 centres O.N.E de la Province de Liège
TRUONG, Thi Thuy-Trâm ULiege; BOLETTE, Amandine ULiege; GUEDERS, Audrey ULiege et al

in Revue Médicale de Liège (2021)

La carie dentaire touche encore 60 à 90% des enfants scolarisés dans le monde. Nous avons collecté les données épidémiologiques de 212 d’enfants de moins de 6 ans fréquentant l’Office de la Naissance et ... [more ▼]

La carie dentaire touche encore 60 à 90% des enfants scolarisés dans le monde. Nous avons collecté les données épidémiologiques de 212 d’enfants de moins de 6 ans fréquentant l’Office de la Naissance et de l’Enfance en Province de Liège. Les relations entre la prévalence de la carie dentaire dans l’échantillon de population étudié et les facteurs de risque ont été analysées. Parmi les 212 enfants examinés, 66% n’ont aucune dent cariée ou obturée, 10.4% ont une dent cariée ou obturée et 23.6% ont au moins 2 dents cariées ou obturées. La prévalence de la maladie carieuse augmente avec l’âge passant de 33% chez les enfants de 3 ans à 44% chez les enfants de 4 ans et 59% chez ceux de 5 ans. De plus, le nombre de dents cariées ou obturées est significativement plus élevé chez les enfants qui se brossent les dents seuls, sans l’aide d’un parent, ou encore chez ceux qui consomment plus fréquemment des boissons ou des collations sucrées. Enfin, le facteur socio-économique influence également la santé dentaire. [less ▲]

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See detailRupture spontanée d’un anévrysme de l’artère splénique au cours du troisième trimestre de la grossesse
VIEUJEAN, Sophie ULiege; Dauby, Morgane ULiege; REMACLE, Geneviève ULiege et al

in Revue Médicale de Liège (2021)

We report the case of a 24-years old female patient with spontaneous rupture of a splenic artery aneurysm in the third trimester of pregnancy. This, throughout the physiological and hormonal changes it ... [more ▼]

We report the case of a 24-years old female patient with spontaneous rupture of a splenic artery aneurysm in the third trimester of pregnancy. This, throughout the physiological and hormonal changes it imposes, promotes the occurrence of aneurysm of the splenic artery and its rupture. Although this is a rare complication, its prognosis is severe and its typical clinical picture associating abdominal pain, hypotension and anemia is misleading for the clinician who likelier evokes a retroplacental hematoma or a uterine rupture. The maternal and foetal survival depends on rapid diagnosis and multidisciplinary management, which is why it‘s important for the clinician to consider this differential diagnosis when abdominal pain or hemoperitoneum occurs in pregnant women. [less ▲]

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See detailIntérêt et limites des outils de dépistage de la dysphagie en gériatrie
DENUIT, Catherine ULiege; Delcourt, Sandrine ULiege; Poncelet, Mélanie ULiege et al

in Revue Médicale de Liège (2021), 76

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See detailComment j’explore… une gonalgie non traumatique
JORIS, Olivier ULiege; DANIEL, Christophe ULiege; KURTH, William ULiege et al

in Revue Médicale de Liège (2021), 76

Because the knee is the joint of the human body with the largest surface, it is no wonder that gonalgia is one of the most common complaints in the general population. Although the management of a painful ... [more ▼]

Because the knee is the joint of the human body with the largest surface, it is no wonder that gonalgia is one of the most common complaints in the general population. Although the management of a painful traumatic knee is relatively well standardized, that of a non-traumatic knee pain is less codified. History and a rigorous systematic cli- nical examination play a key role in the management of nontraumatic gonalgia. The diagnostic approach is mainly guided by the inflammatory or mechanical nature of the pain and its topography. This article aims to clarify the dia- gnostic approach to gonalgia without notion of prior trauma. [less ▲]

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See detailComment j’explore… le protrusio acetabuli chez l’enfant
Kabore, Christophe ULiege; Allington, Nanni ULiege

in Revue Médicale de Liège (2021)

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See detailCervical spondylolysis : a rare fortuitous finding
Bodet, Colin ULiege; BRUYERE, Pierre-Julien ULiege; Ferré, Antoine ULiege et al

in Revue Médicale de Liège (2020), 12(75), 767-769

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See detailPolykystose rénale autosomique dominante : perspective pédiatrique
DACHY, Angélique ULiege; COLLARD, Laure ULiege; KRZESINSKI, Jean-Marie ULiege et al

in Revue Médicale de Liège (2020), 75(12), 775-780

Polycystic kidney disease (PKD) is the most prevalent inherited kidney disease. The disease is usually asymptomatic until adulthood. End-stage renal disease occurs generally after the age of 55 years ... [more ▼]

Polycystic kidney disease (PKD) is the most prevalent inherited kidney disease. The disease is usually asymptomatic until adulthood. End-stage renal disease occurs generally after the age of 55 years, with a large inter-individual variability. Renal cyst formation begins early in life, and animal models have shown that treatments able to prevent the cyst growth slow down the renal function decline. A treatment by tolvaptan is currently used in adults to decelerate PKD progression. Until now there is no consensus about the appropriate time to screen for PKD in children. However, these scientific progresses raise the interest of determining early (i.e. pediatric) predictive markers of renal function decline. [less ▲]

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See detailGestion des admission aux urgences durant la pandémie de COVID-19 au sein du CHU de Liège : Apport d'un centre de tri avancé
GILBERT, Allison ULiege; PIAZZA, Justine ULiege; SZECEL, Julien ULiege et al

in Revue Médicale de Liège (2020), 75(Supplement), 11-17

résumé : La pandémie de COVID-19 a débuté au mois de mars 2020 sur le territoire belge. Elle a contraint nos institu- tions hospitalières à une série de réorganisations singulières soutenues par ... [more ▼]

résumé : La pandémie de COVID-19 a débuté au mois de mars 2020 sur le territoire belge. Elle a contraint nos institu- tions hospitalières à une série de réorganisations singulières soutenues par l’activation du Plan d’Urgence Hospitalier. Cet article a pour objet de décrire l’expérience du Centre Hospitalier Universitaire de Liège (CHU de Liège) durant la pandémie de COVID-19 et de relater l’efficience de la mise en place d’un centre de tri avancé en amont des services d’urgences pour la gestion des admissions hospitalières. Méthodes : dès le 2 Mars 2020, le CHU de Liège a mis en place une infrastructure d’accueil des patients suspects d’infection par le SARS-CoV-2. D’abord initiée au sein de l’institution hospitalière, la nécessité d’une infrastructure indépendante s’est rapidement révélée indispensable et a, dès lors, vu le jour dès la fin du mois de mars, sur les deux sites hospitaliers universitaires. Du 2 mars au 3 mai 2020, l’ensemble des données relatives aux visites au sein des centres de tri avancé ont été collectées (nombre d’ad- missions, motif des visites, examens complémentaires et évolutions cliniques). Résultats : sur la période de l’étude, 3.094 patients ont transité par les centres de tri du CHU de Liège. Cette fréquentation était constituée d’un volume global de 3.431 contacts dont 337 représentaient des réad- missions. La sensibilité et la spécificité des centres de tri en regard de la nécessité d’une hospitalisation étaient, respectivement, de 87,9 % et 93,4 %. Conclusion : notre expérience suggère une efficience optimale des centres de tri avancé, en amont des structures hospitalières tradi- tionnelles, pour orienter de manière appropriée le flux des patients suspects d’infection par le SARS-CoV-2. [less ▲]

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See detailRôle de la médecine physique et réadaptation fonctionnelle dans les suites d’une atteinte au SARS-CoV-2
Sauvant, Céline ULiege; Bodet, Colin ULiege; MORICLET, Tommy ULiege et al

in Revue Médicale de Liège (2020), 75(Supplément 1), 153-158

2020 will be remembered as the year of SARSCoV-2 pandemic which confined most of the world’s population at home. Rehabilitation units will have to face specific challenges to protect the vulnerable in ... [more ▼]

2020 will be remembered as the year of SARSCoV-2 pandemic which confined most of the world’s population at home. Rehabilitation units will have to face specific challenges to protect the vulnerable in-patients. Moreover, they must prepare for post-COVID-19 patients who might suffer from illness consequences or present a post intensive care syndrome secondary to the increased ICU length of stay. The purpose of this paper is to highlight the deficiencies of post-COVID-19 patients and suggest a decision algorithm to best match their needs. [less ▲]

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See detailCas clinique : La mastocytose cutanée pédiatrique.
VAN RYMENAM, Adeline ULiege; SACRE, Jean-Paul ULiege; DEZFOULIAN, Bita ULiege et al

in Revue medicale de Liege (2020), 75(10), 636-638

Mastocytosis are orphan diseases characterized by the accumulation of mast cells in one or more organs. A distinction is made between systemic forms (10 %) and pure cutaneous forms (90 %), the latter ... [more ▼]

Mastocytosis are orphan diseases characterized by the accumulation of mast cells in one or more organs. A distinction is made between systemic forms (10 %) and pure cutaneous forms (90 %), the latter being mainly pediatric and generally having a spontaneously favourable prognosis. In the absence of a systemic sign, the diagnostic criteria for cutaneous mastocytosis are Darier's sign, in principle, pathognomonic, as well as skin histology confirming mast cell infiltration. The treatment is essentially preventive (avoidance of factors triggering degranulation) and symptomatic (antihistamine agents). [less ▲]

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See detailArthropathie hémophilique de la cheville : description de deux cas et revue de la littérature
Pelzer, Doriane ULiege; LAURENT, Charlotte ULiege; PETERS, Pierre ULiege et al

in Revue Médicale de Liège (2020), 75(10), 665-669

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See detailMaladie de Marie et Sainton ou dysostose cléido-crânien
LERUSSE, Julien ULiege; Kaux, Jean-François ULiege

in Revue Médicale de Liège (2020), 75(10), 639-643

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See detailRésilience et réactivité de la médecine générale durant la pandémie COVID-19
Belche, Jean Luc ULiege; Joly, Louise ULiege; Crismer, André ULiege et al

in Revue Médicale de Liège (2020), 75(S1), 29-37

The COVID-19 pandemic has forced general practice to react and adapt its modus operandi in various ways. We describe most important practical adaptations according to the chronology imposed by the ... [more ▼]

The COVID-19 pandemic has forced general practice to react and adapt its modus operandi in various ways. We describe most important practical adaptations according to the chronology imposed by the different phases of this unprecedented crisis, during the first three quarters of 2020. The Belgian health system and all its components have been put under tension. General medicine has been able to build on its strengths but has also suffered from certain weaknesses. Initial lessons must be learnt in order to better respond to the challenges of tomorrow. [less ▲]

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See detailLa déferlante COVID-19 : la PCR à la rescousse ! : Chronique d’une gestion de crise au Laboratoire de Microbiologie clinique du CHU de Liège
Hayette, Marie-Pierre ULiege; MEEX, Cécile ULiege; BONTEMS, Sébastien ULiege et al

in Revue Médicale de Liège (2020), 75(S55-S61), 55-61

The SARS-CoV-2 outbreak in December 2019 in China and its expansion across the world and Europe have requested the participation of clinical laboratories as major players in the diagnosis of COVID-19, to ... [more ▼]

The SARS-CoV-2 outbreak in December 2019 in China and its expansion across the world and Europe have requested the participation of clinical laboratories as major players in the diagnosis of COVID-19, to perform PCR tests mainly on nasopharyngeal swabs. In Belgium, the first confirmed COVID-19 patient was diagnosed in early February, the first of many, especially travelers returning from winter sports. In order to meet the ever-increasing demands for testing, the Clinical Microbiology Laboratory of the CHU of Liege had to adapt to this situation: firstly, by developing manual PCR tests and then automated solutions, permitting to increase the number of analyzes by ensuring a short turnaround time of results. Then, a system for the communication of results on a large scale has been set up, and finally solutions to deal with the lack of sampling devices have been found. This first wave of the pandemic has also highlighted an unprecedented solidarity within the institution. In this article, we recount the chronology of the management of this unprecedented health crisis within the Clinical Microbiology Laboratory of the CHU of Liege. [less ▲]

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See detailDiastématomyélie décelée à l’âge adulte
Grailet, François ULiege; Maillard, Bérengère ULiege; Tomasella, Marco ULiege et al

in Revue Médicale de Liège (2020)

We report a case of a 35-year-old woman with recurrent lumbar pain and left cruralgia in a post-traumatic context, for which the scanner had made possible the fortuitous diagnostic of a congenital anomaly ... [more ▼]

We report a case of a 35-year-old woman with recurrent lumbar pain and left cruralgia in a post-traumatic context, for which the scanner had made possible the fortuitous diagnostic of a congenital anomaly. The diagnosis of diastematomyelia, which is more frequent in utero, is rare in adulthood and results from the implementation of an iconographic assessment. We will present the major malformations that are associated with diastematomyelia and which could evoke the presence of this malformation. The management of the anomaly is still controversial and can lead, if not done properly, to invalidating neurological deteriorations. [less ▲]

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