References of "2010"
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See detailAuditory P300 and the altered consciousness: detecting altered states of consciousness using the P300 speller
Lulé, D.; Kleih, S.; Chatelle, Camille ULiege et al

in Proceedings of TOBI Workshop 2010: Integrating Brain-Computer Interfaces with Conventional Assistive Technology (2010)

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See detailLes donations d'entreprises en region wallonne
Douny, Raphaël ULiege

in Manuel de planification patrimoniale (2010)

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See detailLa sarcopénie: un marqueur de fragilite physique
Weber, J.; Gillain, Sophie ULiege; Petermans, Jean ULiege

in Revue Médicale de Liège (2010), 65(9), 514-20

Sarcopenia is defined by loss of muscular mass, strength and quality that occur in elderly. Multiple factors underlie this process: low physical activity, low steroids hormones, increase of cytokines ... [more ▼]

Sarcopenia is defined by loss of muscular mass, strength and quality that occur in elderly. Multiple factors underlie this process: low physical activity, low steroids hormones, increase of cytokines, loss of motoneurons, decrease of protein synthesis...However, the role of these factors is not yet well understood and consensual clinical definition and assessment are still needed. It has become an important area of research because of its frequency and the influence in the disability of old people. It is a major component of frailty. So far, no pharmacological treatment has proven definitive evidence to treat or prevent sarcopenia. Nevertheless, it needs a multidimensional approach based on physical activity and prevention of malnutrition. [less ▲]

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See detailEl doble juego de una vida y de una obra. Jorge Semprun y la literatura comprometida
Denis, Benoît ULiege

in Pla, Xavier (Ed.) Jorge Semprun o les espirales de la memoria (2010)

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See detailInfezione da Equid herpesvirus (EHV_5) in 15 puledri
Marenzoni, M. L.; Coppola, G.; Maranesi, M. et al

in Ippologia (2010), 21(31-34),

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See detailAn Oedometer for Studying Combined Effects of Temperature and Suction on Soils
François, Bertrand ULiege; Laloui, Lyesse

in Geotechnical Testing Journal (2010), 33(2),

This paper reports the development of an advanced thermo-hydro-mechanical (THM) oedometer in order to characterize the behavior of soils under combined non-isothermal and unsaturated conditions. The ... [more ▼]

This paper reports the development of an advanced thermo-hydro-mechanical (THM) oedometer in order to characterize the behavior of soils under combined non-isothermal and unsaturated conditions. The simultaneous control of temperature, suction, and stress states within the sample required rigorous calibration. This THM oedometer accommodates samples 80 mm in diameter and 23 mm in height. The applied vertical stresses can reach values of up to 1 MPa, the controlled temperature ranges from 20 to 80°C, and the applied suction is up to 500 kPa. The paper thoroughly discusses the calibration of the device and presents some results of tests performed on sandy silt. [less ▲]

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See detailLes donations d'entrprises en region flamande
Douny, Raphaël ULiege

in Manuel de planification patrimoniale (2010)

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See detailPalatoschisis in the dog: developmental mechanisms and etiology
Van Den Berghe, Femke ULiege; Cornillie, Pieter; Stegen, Ludo et al

in Vlaams Diergeneeskunde Tijdschift = Flemish Veterinary Journal (2010)

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See detailMolecular requirements for ethanol differential allosteric modulation of glycine receptors based on selective Gbetagamma modulation.
Yevenes, Gonzalo E; Moraga-Cid, Gustavo; Avila, Ariel et al

in Journal of Biological Chemistry (2010), 285(39), 30203-13

It is now believed that the allosteric modulation produced by ethanol in glycine receptors (GlyRs) depends on alcohol binding to discrete sites within the protein structure. Thus, the differential ethanol ... [more ▼]

It is now believed that the allosteric modulation produced by ethanol in glycine receptors (GlyRs) depends on alcohol binding to discrete sites within the protein structure. Thus, the differential ethanol sensitivity of diverse GlyR isoforms and mutants was explained by the presence of specific residues in putative alcohol pockets. Here, we demonstrate that ethanol sensitivity in two ligand-gated ion receptor members, the GlyR adult alpha(1) and embryonic alpha(2) subunits, can be modified through selective mutations that rescued or impaired Gbetagamma modulation. Even though both isoforms were able to physically interact with Gbetagamma, only the alpha(1) GlyR was functionally modulated by Gbetagamma and pharmacological ethanol concentrations. Remarkably, the simultaneous switching of two transmembrane and a single extracellular residue in alpha(2) GlyRs was enough to generate GlyRs modulated by Gbetagamma and low ethanol concentrations. Interestingly, although we found that these TM residues were different to those in the alcohol binding site, the extracellular residue was recently implicated in conformational changes important to generate a pre-open-activated state that precedes ion channel gating. Thus, these results support the idea that the differential ethanol sensitivity of these two GlyR isoforms rests on conformational changes in transmembrane and extracellular residues within the ion channel structure rather than in differences in alcohol binding pockets. Our results describe the molecular basis for the differential ethanol sensitivity of two ligand-gated ion receptor members based on selective Gbetagamma modulation and provide a new mechanistic framework for allosteric modulations of abuse drugs. [less ▲]

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See detailNon-isothermal infiltration in plastic bentonite
François, Bertrand ULiege; Laloui, Lyesse

in Alonso, Edouardo; Gens, Antonio (Eds.) Unsaturated Soils (2010)

In deep geological repository involving a multi-barrier system, the engineered materials, generally made of bentonite, constitute an important mechanical, thermal and hydraulic barrier to prevent the ... [more ▼]

In deep geological repository involving a multi-barrier system, the engineered materials, generally made of bentonite, constitute an important mechanical, thermal and hydraulic barrier to prevent the interaction between wastes and biosphere. To better understand the THM (thermo-hydro-mechanical) processes in the clayey confining system, experimental tests must be simulated by the means of advance numerical tools. A unified thermo-mechanical constitutive model for unsaturated soils, ACMEG-TS, has been developed and implemented in the finite element code LAGAMINE. Material is considered as tri-phase non-isothermal thermo-plastic medium. The results of numerical simulations of non-isothermal infiltration tests through FEBEX bentonite are compared with the available sensors measurements and interpreted in the light of elasto-thermo-plasticity of unsaturated soils. Through those simulations, the advancements in the understanding of the involved processes brought by the ACMEG-TS model are discussed. [less ▲]

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See detailComparison of accuracy of sonography, rectal palpation, and pregnancy-associated glycoproteins tests for pregnancy diagnosis in cows
Gajewski, Z.; Petrajtis, M.; Melo de Sousa, Noelita ULiege et al

in Proceedings of the XIth Middle European Buiatrics Congress (2010)

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See detailRemoval of Androgens and Estrogens from Water by Reactive Materials
Kai, Cai; Phillips, D. H.; Elliott, Christian et al

in Journal of Water Resource and Protection (2010), 2(11), 990-993

Nowadays, endocrine disruptor compounds in the water system have become a concern due to the risk of contamination to wild life and humans even at the nanogram level. Excess estrogens and androgens are a ... [more ▼]

Nowadays, endocrine disruptor compounds in the water system have become a concern due to the risk of contamination to wild life and humans even at the nanogram level. Excess estrogens and androgens are a major contributor group of endocrine compounds. Statistical surveys have shown that dairy farms contribute to over 90% of the total estrogens in the UK and US. An analytical system is being developed to assess the efficiency of reactive materials to remove target hormonal contaminants from dairy farm effluent. This can be achieved using reporter gene assays (RGAs) to detect low level steroid hormones. A preliminary study comparing the efficiency of granular activated carbon, zero-valent iron, and organoclay was carried out using bench-scale evaluations in negative control HPLC water. Their potential ability to remove testosterone and 17-β- estradiol spiked at reported environmental levels was measured by androgenic and estrogenic luminescent reporter assay respectively. [less ▲]

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See detailRecent Applications of Alkene Metathesis in Fine Chemical Synthesis
Bicchielli, Dario ULiege; Borguet, Yannick ULiege; Delaude, Lionel ULiege et al

in Dragutan, Valerian; Demonceau, Albert; Dragutan, Ileana (Eds.) et al Green Metathesis Chemistry (2010)

During the last decade or so, the emergence of the metathesis reaction in organic synthesis has revolutionised the strategies used for the construction of complex molecular structures. Olefin metathesis ... [more ▼]

During the last decade or so, the emergence of the metathesis reaction in organic synthesis has revolutionised the strategies used for the construction of complex molecular structures. Olefin metathesis is indeed particularly suited for the construction of small open-chain molecules and macrocycles using crossmetathesis and ring-closing metathesis, respectively. These reactions serve, inter alia, as key steps in the synthesis of various agrochemicals and pharmaceuticals such as macrocyclic peptides, cyclic sulfonamides, novel macrolides, or insect pheromones. The present chapter is aiming at illustrating the great synthetic potential of metathesis reactions. Shortcomings, such as the control of olefin geometry and the unpredictable effect of substituents on the reacting olefins, will also be addressed. Examples to be presented include epothilones, amphidinolides, spirofungin A, and archazolid. Synthetic approaches involving silicon-tethered ring-closing metathesis, relay ring-closing metathesis, sequential reactions, domino as well as tandem metathesis reactions will also be illustrated. [less ▲]

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See detailLe Codex de Niketas et la médecine byzantine
Marganne, Marie-Hélène ULiege

in Bernabo, Massimo (Ed.) La collezione di testi chirurgici di Niceta. Firenze, Biblioteca Medicea Laurenziana, Plut. 74.7. Tradizione Medica Classica a Bisanzio (2010)

The Codex of Nikétas (Laurentianus pluteus graecus 74, 7, IXex./Xin.), which contains a collection of sixteen classic papers of surgery covering a period of more thousand years, from Hippocrates (Vex ... [more ▼]

The Codex of Nikétas (Laurentianus pluteus graecus 74, 7, IXex./Xin.), which contains a collection of sixteen classic papers of surgery covering a period of more thousand years, from Hippocrates (Vex./IVin. BC) to Paulus Aegineta (A.D. VII) is exceptional by its age, presentation, conception, magnificent illustration and history. A new examination of the support, writing, contents, as well as of the cultural context, allows to understand better the criteria of selection of the papers, their organization and the pursued objectives, particularly in the treatment of bone and joint diseases. [less ▲]

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See detailComputing bounds for kernel-based policy evaluation in reinforcement learning
Fonteneau, Raphaël ULiege; Murphy, Susan A.; Wehenkel, Louis ULiege et al

Report (2010)

This technical report proposes an approach for computing bounds on the finite-time return of a policy using kernel-based approximators from a sample of trajectories in a continuous state space and ... [more ▼]

This technical report proposes an approach for computing bounds on the finite-time return of a policy using kernel-based approximators from a sample of trajectories in a continuous state space and deterministic framework. [less ▲]

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