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See detailAdditive Effect between Nf-Kappab Subunits and P53 Protein for Transcriptional Activation of Human P53 Promoter
Benoit, V.; Hellin, A. C.; Huygen, S. et al

in Oncogene (2000), 19(41), 4787-94

The tumor suppressor p53 plays a pivotal role in the cellular response to DNA damage as it controls DNA repair, cell cycle arrest and apoptosis. We studied the autoregulation of human p53 gene ... [more ▼]

The tumor suppressor p53 plays a pivotal role in the cellular response to DNA damage as it controls DNA repair, cell cycle arrest and apoptosis. We studied the autoregulation of human p53 gene transcription in colon cancer cell lines. Wild-type p53 has been shown to autoregulate its own transcription either positively or negatively and probably in a cell-type-specific manner. Indeed, a p53 binding site has been described in the human and murine p53 promoters, but a direct binding of wild-type p53 protein to this site has never been reported. In this study, we demonstrated a transactivation of human p53 promoter by wild-type p53 in human colon cancer cells. We identified in the human p53 promoter a novel potential p53-responsive element that binds wild-type p53. Moreover, wild-type p53 protein transactivated a reporter plasmid containing a luciferase gene driven by a minimal promoter harboring this p53 binding site. Finally, as the p53 promoter contains an NF-kappaB binding site, we demonstrated an additive effect when NF-kappaB subunits and p53 protein combined to transactivate the human p53 promoter. [less ▲]

Detailed reference viewed: 18 (4 ULiège)
See detailL’état du logement à Liège
Halleux, Jean-Marie ULiege

Conference given outside the academic context (2000)

Detailed reference viewed: 7 (3 ULiège)
See detailQuality assurance: experience of an university
Chapelle, Jean-Paul ULiege

Conference (2000, September 26)

Detailed reference viewed: 4 (0 ULiège)
Full Text
See detailBehaviour of steel pallet rack structures under exceptional loading conditions - partial report
zaharia, raul; Franssen, Jean-Marc ULiege

Report (2000)

In this report, the general context of steel storage rack systems subjected to fire is first introduced. The second section of the report is dedicated to the numerical finite element modelling of the ... [more ▼]

In this report, the general context of steel storage rack systems subjected to fire is first introduced. The second section of the report is dedicated to the numerical finite element modelling of the resistance and stability behaviour of a system in a particular building under static loading at ambient temperature. [less ▲]

Detailed reference viewed: 86 (0 ULiège)
See detailEffects of moderate rotation on stellar pulsations, nonperturbative methods
Neuforge, C.; Briquet, Maryline ULiege; Scuflaire, R.

Poster (2000, September 25)

Detailed reference viewed: 3 (0 ULiège)
See detailβ Cephei stars and SPBs: excited modes in exciting stars
De Ridder, J.; Aerts, C.; De Cat, P. et al

Poster (2000, September 25)

Detailed reference viewed: 11 (0 ULiège)
See detailEtude INSIGHT – présentation des résultats
Krzesinski, Jean-Marie ULiege

Conference (2000, September 24)

Detailed reference viewed: 8 (3 ULiège)
Peer Reviewed
See detailHydrodechlorination of 1,2-dichloroethane into ethylene : selectivity of Pd-Ag alloys of known surface composition
Heinrichs, Benoît ULiege; Lambert, Stéphanie ULiege; Schoebrechts, Jean-Paul et al

in Heterogeneous Catalysis, Proceedings of the 9th International Symposium (2000, September 23)

Detailed reference viewed: 16 (4 ULiège)
See detailHypertension artérielle et organes-cibles
Krzesinski, Jean-Marie ULiege

Conference (2000, September 21)

Detailed reference viewed: 4 (0 ULiège)
Peer Reviewed
See detailReducing apathy and depressive mood in Alzheimer's disease: A case report
Adam, Stéphane ULiege; Van der Linden, Martial ULiege; Juillerat, Anne-Claude et al

Conference (2000, September 21)

Detailed reference viewed: 16 (0 ULiège)
Peer Reviewed
See detailMemory impairments in depression: Controlled and automatic processes
Jermann, Françoise; Ceschi, Grazia; Adam, Stéphane ULiege et al

Poster (2000, September 21)

Detailed reference viewed: 16 (8 ULiège)
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Peer Reviewed
See detailL'actualité du (futur) permis d'environnement en Région wallonne
Delnoy, Michel ULiege

in Immobilier (2000), 16

Detailed reference viewed: 10 (0 ULiège)
Full Text
See detailUn an de crise de défiance de l’euro : révélation d’une Europe sans avenir ?
Santander, Sébastian ULiege

Article for general public (2000)

Après un an d'existence, l'EURO s'est fort dévalué. Cela s'explique notamment par la difficulté que l'Union européenne a à définir un projet politique commun claire.

Detailed reference viewed: 16 (4 ULiège)
See detailEtudes IDNT-RENAAL
Krzesinski, Jean-Marie ULiege

Conference (2000, September 20)

Detailed reference viewed: 16 (0 ULiège)
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See detailProgrès ou barbarisme ?
Legros, Willy ULiege

Speech/Talk (2000)

Detailed reference viewed: 23 (3 ULiège)
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See detailBiocompatibility of circulating polyethylene glycols (PEG): an approach using bovine serum albumin (BSA) as a protein model
Loret, S; Gilson, Ph; Barakat, I et al

Poster (2000, September 19)

Detailed reference viewed: 13 (0 ULiège)
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Peer Reviewed
See detailMaturation of the small intestine is induced by spermine but not by other similar amines
Peulen, Olivier ULiege; Grandfils, Christian ULiege; Dandrifosse, Guy ULiege

in Pflügers Archiv : European Journal of Physiology (2000, September 19), 440

Detailed reference viewed: 6 (0 ULiège)
Peer Reviewed
See detailChemical Force Microscopy Study of Adhesion Properties of Polyolefin Surfaces
Duwez, Anne-Sophie ULiege; Legras, R.; Nysten, B.

Conference (2000, September 18)

Detailed reference viewed: 4 (1 ULiège)
See detailLe dialogue critique entre l'Iran et l'Union européenne.
Bayramzadeh, Kamal ULiege

Master of advanced studies dissertation (2000)

Detailed reference viewed: 29 (3 ULiège)