References of "VAN LINTHOUT, Christine"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailAnomalie d'Ebstein : du diagnostic prenatal au traitement chirurgical.
Madani, Shayan ULiege; VAN LINTHOUT, Christine ULiege; Rondia, Gilles ULiege et al

in Revue medicale de Liege (2020), 75(1), 43-48

Ebstein's anomaly is a rare and complex congenital heart disease involving abnormal embryological development of the tricuspid valve. Its exact prevalence remains unknown given the under-diagnosis of ... [more ▼]

Ebstein's anomaly is a rare and complex congenital heart disease involving abnormal embryological development of the tricuspid valve. Its exact prevalence remains unknown given the under-diagnosis of minor forms and the broad clinical spectrum of this pathology resulting from the highly variable tricuspid morphology. Echocardiography plays an important role in diagnosis, assessment and prognostic evaluation of this condition. We present the case of a 6-year-old boy born from a twin pregnancy with a severe neonatal EA diagnosed by ultrasound at 29 weeks of gestation and we discuss the management on the light of the recent literature. [less ▲]

Detailed reference viewed: 45 (4 ULiège)
Full Text
Peer Reviewed
See detailL’induction élective du travail chez la patiente nullipare : stop ou encore ?
TREMBLAY LEMOINE, Pierre Luc ULiege; Van Linthout, Christine ULiege; Emonts, Patrick ULiege et al

in Revue medicale de Liege (2020), 75(10), 676-681

In Wallonia, almost one fourth of cesarean sections are performed on nulliparous women with vertex nonanomalous singleton gestations who underwent induction of labor. The purpose of this study is to ... [more ▼]

In Wallonia, almost one fourth of cesarean sections are performed on nulliparous women with vertex nonanomalous singleton gestations who underwent induction of labor. The purpose of this study is to compare maternal and neonatal outcomes with elective induction of labor versus spontaneous onset of labor. Data for all deliveries at CHU de Liège over a two-year period were obtained. Women with vertex nonanomalous singleton gestations who delivered from 3900 to 40+6 weeks were selected. We tested the association of elective induction and operative vaginal delivery, cesarean section, post-partum hemorrhage, episiotomy and perineal lacerations, length of labor, length of stay, 1-min and 5-min APGAR inferior to 7 and admission to neonatal intensive care unit. Length of stay was significantly longer in all induced women. In nulliparous women, there was a 45 % probability of operative vaginal delivery or cesarean section delivery in those who underwent elective induction of labor. In light of these results, it seems that our policy of elective induction of labor in nulliparous women is causing unnecessary and potentially avoidable interventions. [less ▲]

Detailed reference viewed: 111 (23 ULiège)
Full Text
See detailA series of 9 pregnancies with hyperthyroidism and Graves disease : fetal and maternal follow up
DELANNOY, Pauline ULiege; GRANDFILS, Sébastien ULiege; LEBRETHON, Marie-Christine ULiege et al

in Abstract book : Annual congress of the Belgian Society of Internal Medicine (2019, December)

Detailed reference viewed: 70 (16 ULiège)
Full Text
Peer Reviewed
See detailBiomarkers of neonatal stress assessment: A prospective study.
ROUATBI, Hatem ULiege; Zigabe, Serge; Gkiougki, Eva et al

in Early Human Development (2019), 137

INTRODUCTION: Early diagnosis of perinatal asphyxia, the major cause of neonatal mortality and morbidity, might be improved by the detection of neonatal stress biomarkers such as cardiac troponin (CTn)T ... [more ▼]

INTRODUCTION: Early diagnosis of perinatal asphyxia, the major cause of neonatal mortality and morbidity, might be improved by the detection of neonatal stress biomarkers such as cardiac troponin (CTn)T, CTnI, NT-Terminal-pro-Brain Natriuretic Peptide (NT-pro-BNP), copeptin, and high sensitivity C-reactive protein (hs-CRP). However, reference values in neonates are lacking. The objective of our study was therefore to establish a reference range of these biomarkers in healthy full term newborns and to analyze the influence of delivery mode on their cord blood concentrations. PATIENTS AND METHODS: CTnT, CTnI, NT-pro-BNP, Copeptin and hs-CRP levels were determined in 201 neonates enrolled in this prospective study and correlated to the delivery mode and post-natal outcome. RESULTS: Using the 99th percentile, the upper reference limit in healthy newborns was established for all biomarkers. Neonates born after complicated delivery had significantly higher values of CTnT, CTnI and Copeptin than those born after uncomplicated delivery. In the multiple regression models with CTnT as dependent variable, the delivery mode was the statistically significant independent variable. CONCLUSION: In this study, we established reference values of cord blood concentrations of cardiac stress biomarkers in healthy newborns. We showed that cardiac-related birth stress is dependent on delivery mode. [less ▲]

Detailed reference viewed: 50 (8 ULiège)
Full Text
Peer Reviewed
See detailCardiac stress biomarkers in neonates: role of the delivery mode
ROUATBI, Hatem ULiege; Gkiouki, E.; Zigabe, Serge et al

Poster (2019, May)

Detailed reference viewed: 34 (7 ULiège)
Full Text
Peer Reviewed
See detailBloc auriculoventriculaire congénital révélateur d’une pathologie maternelle systémique: Physiopathologie et approches thérapeutiques
Collée, Julie ULiege; MALAISE, Olivier ULiege; Emonts, Patrick ULiege et al

in Revue Médicale de Liège (2019), 74(2), 95-99

Summary: Immunologic congenital atrioventricular block is due to the presence of anti-SSA and anti-SSB antibodies in maternal blood. This pathology is often diagnosed when the status is irreversible and ... [more ▼]

Summary: Immunologic congenital atrioventricular block is due to the presence of anti-SSA and anti-SSB antibodies in maternal blood. This pathology is often diagnosed when the status is irreversible and is consequently associated with a high morbi-mortality. Close monitoring for high risk pregnancies can help to diagnose first and second degrees heart block and treatments can be offered when the block is still reversible. Fluorocorticoids, betamimetics and hydroxychloroquine use is not consensual. Studies are still in progress to prove their utility. We report the antenatal managing of a patient in which Goujerot-Sjögren disease was diagnosed after the revealing of an atrioventricular block in her fetus. After a brief physiopathological description, we present the current knowledge in preventive and curative treatments. © 2019 Revue Medicale de Liege. All Rights Reserved. [less ▲]

Detailed reference viewed: 54 (8 ULiège)
Full Text
Peer Reviewed
See detailVariation of the maximum velocity along the umbilical vein supports the Reynolds pulsometer modela
CAPELLE, Xavier ULiege; Schaaps, Jean-Pierre ULiege; BAVI DIDO, Jean-Vincent ULiege et al

in Journal of Gynecology Obstetrics and Human Reproduction (2019)

Objective: To challenge, with a modern sonographic approach and a numerical model, the Reynolds's concept which suggests that the vascular structure of the umbilical cord could act as a pulsometer ... [more ▼]

Objective: To challenge, with a modern sonographic approach and a numerical model, the Reynolds's concept which suggests that the vascular structure of the umbilical cord could act as a pulsometer facilitating the venous return to the foetus. Method: Forty-five patients between 20 and 28 weeks of gestation were included in the study. The blood maximum velocity in the umbilical vein, measured at both foetal and placental ends, was assessed. Several sonographic parameters of the cord, including the diameter of the umbilical vein at both extremities, cord cross-sectional area and Wharton's jelly section surface were measured. We compare our data with those of a numerical model. Results: A difference in maximum velocity between the two extremities of the umbilical vein (ΔUV Vmax) was noted. The maximum velocity was significantly higher at the foetal umbilical end (14.12 +/-3.18 cm/s) than at the placental end (11.93 +/-2.55 cm/s; p < 0.0001). The mean difference is 2.2 +/- 2.3 cm/s. No difference in the umbilical vein diameter was measured at both cord ends (umbilical 4.85 +/-0.9 mm, placental 4.86 +/-0.87 mm, p < 0.0001). There is no significant relationship between ΔUV Vmax and the cord cross-sectional area or Wharton's jelly index. Conclusion: Modifications of the spatial velocity profile together with the pulsometer model could explain the maximum velocity changes that is measured in the umbilical vein along the cord. This numerical model consolidates the sonographic observations. © 2019 [less ▲]

Detailed reference viewed: 61 (18 ULiège)
Full Text
Peer Reviewed
See detailChoix du lieu de naissance du fœtus cardiopathe: Expérience liégeoise et recomm andations internationales
VAN LINTHOUT, Christine ULiege; Brulmans, C.; CAPELLE, Xavier ULiege et al

in Revue Médicale de Liège (2018), 73(1), 28-33

Optimal choice of delivery site after a diagnosis of congenital heart disease (CHD) improves neonatal mortality and morbidity. We report the CHU of Liége experience and review the international ... [more ▼]

Optimal choice of delivery site after a diagnosis of congenital heart disease (CHD) improves neonatal mortality and morbidity. We report the CHU of Liége experience and review the international recommendations. Between 2011 and 2016, 54 fetuses were diagnosed with CHD in our service. Retrospectively we estimated the appropriateness of the site of delivery considering the postnatal outcome. We confronted our experience with the recent international recommendations for in utero transfer to a tertiary center. The latter are based on the risk of hemodynamic instability at birth but differ for the ductal-dependent cardiopathy. The postanatal evolution and the low emergency transfer rate (4 %) in our series demonstrate the quality of our policy. We propose to validate the French transfer in utero recommendations for our obstetrical department, especially for ductal-dependent cardiopathy. [less ▲]

Detailed reference viewed: 32 (0 ULiège)
Full Text
Peer Reviewed
See detailLe cas clinique du mois: découverte fortuite d’anomalies génétiques maternelles lors du test prénatal non invasif
Leonard, Françoise; Gueben, Renaud ULiege; Gueben, Robin ULiege et al

in Revue Médicale de Liège (2018), 73(1),

Le test prénatal non invasif (TPNI) a été intro- duit récemment dans notre pratique clinique. La sensibilité et la spécificité de cette méthode pour le dépistage des principales aneuploïdies ... [more ▼]

Le test prénatal non invasif (TPNI) a été intro- duit récemment dans notre pratique clinique. La sensibilité et la spécificité de cette méthode pour le dépistage des principales aneuploïdies fœtales est de l’ordre de 99%. À cause de l’existence de faux positifs et de faux négatifs, cette technique reste un test de dépistage, non de diagnos- tic. Les résultats discordants s’expliquent par la méthode elle-même qui analyse la totalité de l’ADN libre circulant dans le sang maternel : l’ADN fœtal provenant de la lyse des cellules trophoblastiques, mais aussi l’ADN d’origine maternelle. La mosaïque confinée au placenta est la cause principale des faux positifs décrits dans la littérature. Plus rarement, le TPNI peut mettre en évidence des anomalies maternelles. Nous rapportons le cas de deux patientes por- teuses d’une anomalie cytogénétique révélée par le TPNI : une microduplication 22q11.2 et une anomalie des chromosomes sexuels [less ▲]

Detailed reference viewed: 198 (10 ULiège)
Full Text
Peer Reviewed
See detailChoix du lieu de naissance du foetus cardiopathe. Expérience liégeoise et recommandations internationales
VAN LINTHOUT, Christine ULiege; Brulmans, Clémentine ULiege; CAPELLE, Xavier ULiege et al

in Revue Médicale de Liège (2018), 73(1), 28-33

Optimal choice of delivery site after a diagnosis of congenital heart disease (CHD) improves neonatal mortality and morbidity. We report the CHU of Liège experience and review the international ... [more ▼]

Optimal choice of delivery site after a diagnosis of congenital heart disease (CHD) improves neonatal mortality and morbidity. We report the CHU of Liège experience and review the international recommendations. Between 2011 and 2016, 54 fetuses were diagnosed with CHD in our service. Retrospectively we estimated the appropriateness of the site of delivery considering the postnatal outcome. We confronted our experience with the recent international recommendations for in utero transfer to a tertiary center. The latter are based on the risk of hemodynamic instability at birth but differ for the ductal-dependent cardiopathy. The postanatal evolution and the low emergency transfer rate (4 %) in our series demonstrate the quality of our policy. We propose to validate the French transfer in utero recommendations for our obstetrical department, especially for ductal-dependent cardiopathy. [less ▲]

Detailed reference viewed: 124 (15 ULiège)
Full Text
Peer Reviewed
See detailImpact of the angle used in 2D Ultrasonography on the foetal femur diaphysis measurement
VAN LINTHOUT, Christine ULiege; Lincé, Anouck ULiege; CAPELLE, Xavier ULiege et al

in Facts, Views and Vision in Obgyn (2017), 9(2), 101-104

Objective: The purpose of this pilot study is to compare the 2D scanning measurement of the foetal femoral diaphysis using anterior or lateral/external incidence at ultrasound. Methods: In August 2016, 30 ... [more ▼]

Objective: The purpose of this pilot study is to compare the 2D scanning measurement of the foetal femoral diaphysis using anterior or lateral/external incidence at ultrasound. Methods: In August 2016, 30 consecutive patients underwent a second trimester morphology ultrasound between 21 and 24 weeks of gestation by a senior sonographist. In each case, the femur length was measured either with an anterior angle, estimating the straight aspect of the diaphysis or with a lateral angle, assessing its curved aspect. The two measures were collected prospectively. The difference between paired measurements was calculated and expressed in percentage (mm) and in percentile. Results: The median difference between the two ultrasound angles in terms of femur length was 3,55% and in terms of percentile variation was 17,16. Conclusion: An anterior angle of measurement of the femur length seems to allow an optimal measure of the straight and longest aspect of the diaphysis. According to our results, this angle should be considered when scoring the quality of a morphological ultrasound, but further and larger studies should be done to confirm our hypothesis. [less ▲]

Detailed reference viewed: 49 (5 ULiège)
Full Text
Peer Reviewed
See detailWhen baby's heart reveals mum's disease : Diagnosis of Sjögren's disease in a woman whose fetus shows complete atrioventricular block
André, Hélène; VAN LINTHOUT, Christine ULiege; Gewillig, Marc et al

in Belgian Journal of Paediatrics (2017, March), 19(1), 30

Detailed reference viewed: 34 (7 ULiège)
Full Text
Peer Reviewed
See detailImpact of the angle used in 2D Ultrasonography on the foetal femur diaphysis measurement
Lincé, Anouck ULiege; CAPELLE, Xavier ULiege; LEPAGE, Sylvie ULiege et al

in Facts, Views and Vision in Obgyn (2017), 9(2), 101

Objective: The purpose of this pilot study is to compare the 2D scanning measurement of the foetal femoral diaphysis using anterior or lateral/external incidence at ultrasound. Methods: In August 2016, 30 ... [more ▼]

Objective: The purpose of this pilot study is to compare the 2D scanning measurement of the foetal femoral diaphysis using anterior or lateral/external incidence at ultrasound. Methods: In August 2016, 30 consecutive patients underwent a second trimester morphology ultrasound between 21 and 24 weeks of gestation by a senior sonographist. In each case, the femur length was measured either with an anterior angle, estimating the straight aspect of the diaphysis or with a lateral angle, assessing its curved aspect. The two measures were collected prospectively. The difference between paired measurements was calculated and expressed in percentage (mm) and in percentile. Results: The median difference between the two ultrasound angles in terms of femur length was 3,55% and in terms of percentile variation was 17,16. Conclusion: An anterior angle of measurement of the femur length seems to allow an optimal measure of the straight and longest aspect of the diaphysis. According to our results, this angle should be considered when scoring the quality of a morphological ultrasound, but further and larger studies should be done to confirm our hypothesis. [less ▲]

Detailed reference viewed: 28 (2 ULiège)
Full Text
Peer Reviewed
See detailLe cas clinique du mois. Actinomycose pelvienne pseudo-tumorale : il fallait y penser
KAKKOS, Athanasios ULiege; GONNE, Elodie ULiege; COIMBRA MARQUES, Carla ULiege et al

in Revue Médicale de Liège (2017), 72(1), 10-13

Detailed reference viewed: 249 (27 ULiège)
Full Text
Peer Reviewed
See detailRole of inflammatory- and growth factors in the pathophysiology of gestational diabetes-related complications in neonates
Guffins, Amandine; FARHAT, Nesrine ULiege; GKIOUGKI, Evangelia ULiege et al

in Belgian Journal of Paediatrics (2016), 18(1), 82

Detailed reference viewed: 35 (1 ULiège)
Full Text
Peer Reviewed
See detailPrenatal diagnosis of a terminal chromosome 1 (q42-q44) deletion : original case report and review of the literature
VAN LINTHOUT, Christine ULiege; EMONARD, Violaine ULiege; GATOT, Jean-Stéphane ULiege et al

in Facts, Views and Vision in Obgyn (2016), 8(2), 101-103

Terminal chromosome 1q deletion is rarely reported but causes typical malformations that have been well described in childhood. Clinical features include facial dysmorphy, growth and/or psychomotor ... [more ▼]

Terminal chromosome 1q deletion is rarely reported but causes typical malformations that have been well described in childhood. Clinical features include facial dysmorphy, growth and/or psychomotor retardation, brain agenesis or hypoplasia of the corpus callosum, epilepsy and occasional urogenital or cardiac malformations. The diagnosis of this condition is usually made at birth. The rare cases of antenatal diagnosis were based on microcephaly and growth retardation. In the present case, the foetus presented with an hypoplasia of the corpus callosum, a dysmorphic profile and a single umbilical artery. The foetal echocardiography suggested a noncompaction of the left ventricular myocardium. No microcephaly or growth retardation were noted. We compare our antenatal findings to those described in the literature with the aim to better define the antenatal phenotype of the terminal chromosome 1 deletion syndrome. [less ▲]

Detailed reference viewed: 53 (7 ULiège)
Full Text
Peer Reviewed
See detailDoes gestational diabetes influence foetal organ function ?
Guffins, Amandine ULiege; FARHAT, Nesrine ULiege; GKIOUGKI, Evangelia ULiege et al

in Tijdschrift van de Belgische Kinderarts (2015, January), 17(1), 99

Detailed reference viewed: 32 (5 ULiège)
Full Text
Peer Reviewed
See detailLe situs inversus abdominal incomplet avec malrotation : à propos d'un cas clinique
CUPERS, Stéphanie ULiege; Lambert, M.; VAN LINTHOUT, Christine ULiege et al

Conference (2014, March)

Detailed reference viewed: 151 (8 ULiège)