References of "Charland-Verville, Vanessa"
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See detailLes expériences de mort imminente
Cassol, Helena ULiege; Martial, Charlotte ULiege; Laureys, Steven ULiege et al

in MethIS (in press)

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See detailA Heartbeat Away From Consciousness: Heart Rate Variability Entropy Can Discriminate Disorders of Consciousness and Is Correlated With Resting-State fMRI Brain Connectivity of the Central Autonomic Network
Riganello, Francesco; Larroque, Stephen ULiege; Bahri, Mohamed Ali ULiege et al

in Frontiers in Neurology (2018)

Background: Disorders of consciousness are challenging to diagnose, with inconsistent behavioral responses, motor and cognitive disabilities, leading to approximately 40% misdiagnoses. Heart rate ... [more ▼]

Background: Disorders of consciousness are challenging to diagnose, with inconsistent behavioral responses, motor and cognitive disabilities, leading to approximately 40% misdiagnoses. Heart rate variability (HRV) reflects the complexity of the heart-brain two-way dynamic interactions. HRV entropy analysis quantifies the unpredictability and complexity of the heart rate beats intervals. We here investigate the complexity index (CI), a score of HRV complexity by aggregating the non-linear multi-scale entropies over a range of time scales, and its discriminative power in chronic patients with unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS), and its relation to brain functional connectivity. Methods: We investigated the CI in short (CIs) and long (CIl) time scales in 14 UWS and 16 MCS sedated. CI for MCS and UWS groups were compared using a Mann-Whitney exact test. Spearman's correlation tests were conducted between the Coma Recovery Scale-revised (CRS-R) and both CI. Discriminative power of both CI was assessed with One-R machine learning model. Correlation between CI and brain connectivity (detected with functional magnetic resonance imagery using seed-based and hypothesis-free intrinsic connectivity) was investigated using a linear regression in a subgroup of 10 UWS and 11 MCS patients with sufficient image quality. Results: Higher CIs and CIl values were observed in MCS compared to UWS. Positive correlations were found between CRS-R and both CI. The One-R classifier selected CIl as the best discriminator between UWS and MCS with 90% accuracy, 7% false positive and 13% false negative rates after a 10-fold cross-validation test. Positive correlations were observed between both CI and the recovery of functional connectivity of brain areas belonging to the central autonomic networks (CAN). Conclusion: CI of MCS compared to UWS patients has high discriminative power and low false negative rate at one third of the estimated human assessors' misdiagnosis, providing an easy, inexpensive and non-invasive diagnostic tool. CI reflects functional connectivity changes in the CAN, suggesting that CI can provide an indirect way to screen and monitor connectivity changes in this neural system. Future studies should assess the extent of CI's predictive power in a larger cohort of patients and prognostic power in acute patients. [less ▲]

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See detailHypnosis: from science to clinic
FAYMONVILLE, Marie-Elisabeth ULiege; LAUREYS, Steven ULiege; Martial, Charlotte ULiege et al

Conference (2018, August 24)

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See detailMemories of near-death experiences: Are they self-defining?
Cassol, Helena ULiege; D'Argembeau, Arnaud ULiege; Charland-Verville, Vanessa ULiege et al

Poster (2018, June 28)

Introduction. Memories of near-death experiences (NDEs) are characterized by a rich phenomenology and appear to be firmly anchored. It has been proposed that this phenomenology could be explained by the ... [more ▼]

Introduction. Memories of near-death experiences (NDEs) are characterized by a rich phenomenology and appear to be firmly anchored. It has been proposed that this phenomenology could be explained by the significance of NDEs for personal identity; however, the centrality of this event to individuals’ (so-called “experiencers”) lives and identities remains unexplored. Objectives. Given the significance and consequentiality of NDEs, this study aimed at determining whether memories of NDEs could be considered as a particular type of autobiographical memories, referred to as “Self-Defining Memories” (SDMs), which are central to one’s self-understanding. Furthermore, we intended to explore if NDEs memories are more central to experiencers’ identities and life stories as compared to other SDMs. Methods. We recruited 47 volunteers who had experienced a NDE (identified using the Greyson NDE scale) in a life threatening situation. Volunteers were invited to complete a task asking to describe two SDMs and, for each of them, they completed the Centrality of Event Scale (CES). Results. The majority of volunteers (60%) recalled their NDE among the reported SDMs. The memory of the NDE scored significantly higher on the CES as compared to the other SDM, showing that this experience was considered as being particularly central to their identity. Furthermore, we found that volunteers who described more intense NDEs memories also considered them as more central to their identities. Conclusions. The self-defining status of NDEs memories confirms that they are central to experiencers’ identities and highlights the importance for clinicians to facilitate their integration within the self. [less ▲]

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See detailA Heartbeat Away From Consciousness: Heart Rate Variability Entropy can discriminate disorders of consciousness and is correlated with resting-state fMRI brain connectivity of the Central Autonomic Network
Riganello, Francesco ULiege; Larroque, Stephen Karl ULiege; Bahri, Mohamed Ali ULiege et al

Poster (2018, June 21)

Motivation: Heart rate variability (HRV) reflects the heart-brain two-way dynamic interactions[1-5]. HRV entropy analysis quantifies the unpredictability and complexity of the heart rate beats intervals ... [more ▼]

Motivation: Heart rate variability (HRV) reflects the heart-brain two-way dynamic interactions[1-5]. HRV entropy analysis quantifies the unpredictability and complexity of the heart rate beats intervals and over multiple time scales using multiscale entropy (MSE)[6-8]. The complexity index (CI) provides a score of a system’s complexity by aggregating the MSE measures over a range of time scales[8]. Most HRV entropy studies have focused on acute traumatic patients using task-based designs[9]. We here investigate the CI and its discriminative power in chronic patients with unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS) at rest, and its relation to brain functional connectivity. Methods: We investigated the CI in short (CIs) and long (CIl) time scales in 16 UWS and 17 MCS sedated. CI for MCS and UWS groups were compared using a Mann-Whitney exact test. Spearman’s correlation tests were conducted between the Coma Recovery Scale-revised (CRS-R) and both CI. Discriminative power of both CI was assessed with One-R machine learning model. Correlation between CI and brain connectivity (detected with functional magnetic resonance imagery using seed-based and hypothesis-free intrinsic connectivity) was investigated using a linear regression in a subgroup of 12 UWS and 12 MCS patients with sufficient image quality. Results and Discussion: Significant differences were found between MCS and UWS for CIs and CIl (0.0001≤p≤0.006). Significant correlations were found between CRS-R and CIs and CIl (0.0001≤p≤0.026). The One-R classifier selected CIl as the best discriminator between UWS and MCS with 85% accuracy, 19% false positive rate and 12% false negative rate after a 10-fold cross-validation test. Positive correlations were observed between CI and brain areas belonging to the autonomic system. CI was found to be significantly higher in MCS compared to UWS patients, with high discriminative power and lower false negative rate than the reported misdiagnosis rate of human assessors, providing an easy, inexpensive and non-invasive diagnosis tool. CI is correlated to functional connectivity changes in brain regions belonging to the autonomic nervous system, suggesting that CI can provide an indirect way to screen and monitor connectivity changes in this neural system. Future studies should investigate further the extent of CI’s predictive power for other pathologies in the disorders of consciousness spectrum. [less ▲]

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See detailFantasy proneness in near-death experiencers
Martial, Charlotte ULiege; Cassol, Helena ULiege; CHARLAND-VERVILLE, Vanessa ULiege et al

Poster (2018, June)

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See detailFantasy proneness correlates with the intensity of near-death experience
Martial, Charlotte ULiege; Cassol, Helena ULiege; Charland-Verville, Vanessa ULiege et al

in Frontiers in Psychiatry (2018)

Little is known about the personality characteristics of those who have experienced a “Near-Death Experience” (NDE). One interesting candidate is fantasy proneness. We studied this trait in individuals ... [more ▼]

Little is known about the personality characteristics of those who have experienced a “Near-Death Experience” (NDE). One interesting candidate is fantasy proneness. We studied this trait in individuals who developed NDEs in the presence (i.e., classical NDEs) or absence (i.e., NDEs-like) of a life-threatening situation. We surveyed a total of 228 individuals. From those, 108 qualified as NDE experiencers (i.e., Greyson NDE scale total score ≥ 7): 51 had their NDEs in the context of a life‐threatening situation; 57 had their NDEs not related to a life-threatening situation. From those who did not meet the criteria to be considered “experiencers”, 20 had their NDE in the absence of a life-threatening situation; 50 had faced death but did not recall a NDE and finally, 50 were healthy people without a history of life threat and/or NDE. All participants completed a measure of NDE intensity (the Greyson NDE scale) and a measure of fantasy proneness (the Creative Experiences Questionnaire). People reporting NDEs-like scored higher on fantasy proneness than those reporting classical NDEs, individuals whose experiences did not meet the NDE criteria and matched controls. By contrast, individuals reporting classical NDEs showed similar engagement in fantasy as matched controls. The reported intensity of the experiences was positively correlated with engagement in fantasy. Our findings support the view that strong engagement in fantasy by individuals recalling NDEs-like might make these persons more likely to report such subjective experiences when exposed to suitable physiological and/or psychological conditions (e.g., meditation, syncope). [less ▲]

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See detailVivid memories from hell: A systematic analysis of distressing near-death experiences accounts
Cassol, Helena ULiege; Martial, Charlotte ULiege; Annen, Jitka ULiege et al

Poster (2018, May 18)

Background: Near-death experiences (NDEs) are associated to positive affects, however, a small proportion is depicted as distressing. Only a few studies have addressed these frightening events, and yet ... [more ▼]

Background: Near-death experiences (NDEs) are associated to positive affects, however, a small proportion is depicted as distressing. Only a few studies have addressed these frightening events, and yet they could trigger long-lasting emotional trauma. Objectives: We aimed at 1) looking into the proportion of distressing NDEs in a sample of NDE narratives; 2) running a categorization of distressing narratives based on Greyson and Bush’s classification: “inverse”, “void” or “hellish” NDEs; and 3) comparing the content of distressing NDEs with “classical” NDEs (which include typical features and are not considered as negative). Methods: NDE experiencers were invited to write down their experience and complete the Memory Characteristics Questionnaire (to assess its phenomenological characteristics) as well as the Greyson NDE scale (to characterize the content of the NDE). Distressing narratives were identified and a text analysis was conducted to classify each narrative into one of the negative subcategories. Content and intensity of distressing and classical NDEs memories were then compared using Mann Whitney U tests based on answers to questionnaires. Results: First, we found that distressing NDEs represent 18% of our sample. Second, the text analysis confirmed Greyson and Bush’s classification and highlighted that our subsample includes 14 inverse (56%), 8 hellish (32%) and 3 void (12%) accounts. Finally, memories of distressing NDEs are considered as detailed as memories of classical NDEs. Apart from positive affects, distressing NDEs contain as much typical features as classical NDEs. Still poorly studied, distressing NDEs deserve careful consideration to ensure their integration into NDE experiencers’ identity. [less ▲]

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See detailAre memories of near-death experiences self-defining?
Cassol, Helena ULiege; D'Argembeau, Arnaud ULiege; Charland-Verville, Vanessa ULiege et al

Conference (2018, May 18)

Introduction. Memories of near-death experiences (NDEs) are characterized by a rich phenomenology and appear to be firmly anchored. It has been proposed that this phenomenology could be explained by the ... [more ▼]

Introduction. Memories of near-death experiences (NDEs) are characterized by a rich phenomenology and appear to be firmly anchored. It has been proposed that this phenomenology could be explained by the significance of NDEs for personal identity; however, the centrality of this event to individuals’ (so-called “experiencers”) lives and identities remains unexplored. Objectives. Given the significance and consequentiality of NDEs, this study aimed at determining whether memories of NDEs could be considered as a particular type of autobiographical memories, referred to as “Self-Defining Memories” (SDMs), which are central to one’s self-understanding. Furthermore, we intended to explore if NDEs memories are more central to experiencers’ identities and life stories as compared to other SDMs. Methods. We recruited 47 volunteers who had experienced a NDE (identified using the Greyson NDE scale) in a life threatening situation. Volunteers were invited to complete a task asking to describe two SDMs and, for each of them, they completed the Centrality of Event Scale (CES). Results. The majority of volunteers (60%) recalled their NDE among the reported SDMs. The memory of the NDE scored significantly higher on the CES as compared to the other SDM, showing that this experience was considered as being particularly central to their identity. Furthermore, we found that volunteers who described more intense NDEs memories also considered them as more central to their identities. Conclusions. The self-defining status of NDEs memories confirms that they are central to experiencers’ identities and highlights the importance for clinicians to facilitate their integration within the self. [less ▲]

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See detailQualitative thematic analysis of the phenomenology of near-death experiences
Cassol, Helena ULiege; Pétré, Benoît ULiege; Degrange, Sophie ULiege et al

in PLoS ONE (2018)

Near-death experiences (NDEs) refer to profound psychological events that can have an important impact on the experiencers’ (NDErs) lives. Previous studies have shown that NDEs memories are ... [more ▼]

Near-death experiences (NDEs) refer to profound psychological events that can have an important impact on the experiencers’ (NDErs) lives. Previous studies have shown that NDEs memories are phenomenologically rich. In the present study, we therefore aimed to extract the common themes (referred to as “features” in the NDE literature) reported by NDErs by analyzing all the concepts stored in the narratives of their experiences. A qualitative thematic analysis has been carried out on 34 cardiac arrest survivors’ NDE narratives. Our results shed the light on the structure of the narratives by identifying 10 “time-bounded” themes which refer to isolated events encountered during the NDE and 1 “transversal” theme which characterizes the whole narrative and generally appears as a retrospective comment of self-reflection on the experience. The division of narratives into themes provides us with detailed information about the vocabulary used by NDErs to describe their experience. This established thematic method enables a rigorous description of the phenomenon, ensuring the inclusion of all self-reported manifestations of themes in narratives. [less ▲]

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See detailResistance to eye opening in patients with disorders of consciousness
van Ommen, H. J.; Thibaut, Aurore ULiege; VANHAUDENHUYSE, Audrey ULiege et al

in Journal of Neurology (2018)

Introduction: Resistance to eye opening (REO) is a commonly encountered phenomenon in clinical practice. We aim to investigate whether REO is a sign of consciousness or a reflex in severely brain-injured ... [more ▼]

Introduction: Resistance to eye opening (REO) is a commonly encountered phenomenon in clinical practice. We aim to investigate whether REO is a sign of consciousness or a reflex in severely brain-injured patients. Methods: We recorded REO in chronic patients with disorders of consciousness during a multimodal diagnostic assessment. REO evaluations were performed daily in each patient and clinical diagnosis of unresponsive wakefulness syndrome (UWS), minimally conscious state with (MCS+) or without (MCS−) preserved language processing was made using the Coma Recovery Scale-Revised (CRS-R). Results: Out of 150 consecutive patients, 79 patients fit inclusion criteria. REO was seen in 19 patients (24.1%). At the group level, there was a significant relationship between the presence of REO and the level of consciousness. We also observed a difference in the repeatability of REO between patients in UWS, MCS− and MCS+. Out of 23 patients in UWS, six showed REO, in whom five showed atypical brain patterns activation. Conclusion: Our findings suggest a voluntary basis for REO and stress the need for multiple serial assessments of REO in these patients, especially since most patients show fluctuating levels of consciousness. © 2018 Springer-Verlag GmbH Germany, part of Springer Nature [less ▲]

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See detailCorrigendum: Temporality of Features in Near-Death Experience Narratives
Martial, Charlotte ULiege; Cassol, Helena ULiege; Antonopoulos, Georgios ULiege et al

in Frontiers in Human Neuroscience (2017)

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See detailTemporality of Features in Near-Death Experience Narratives
Martial, Charlotte ULiege; Cassol, Helena ULiege; Antonopoulos, Georgios ULiege et al

in Frontiers in Human Neuroscience (2017)

Background: After an occurrence of a Near-Death Experience (NDE), Near- Death Experiencers (NDErs) usually report extremely rich and detailed narratives. Phenomenologically, a NDE can be described as a ... [more ▼]

Background: After an occurrence of a Near-Death Experience (NDE), Near- Death Experiencers (NDErs) usually report extremely rich and detailed narratives. Phenomenologically, a NDE can be described as a set of distinguishable features. Some authors have proposed regular patterns of NDEs, however, the actual temporality sequence of NDE core features remains a little explored area. Objectives: The aim of the present study was to investigate the frequency distribution of these features (globally and according to the position of features in narratives) as well as the most frequently reported temporality sequences of features. Methods: We collected 154 French freely expressed written NDE narratives (i.e., Greyson NDE scale total score 7/32). A text analysis was conducted on all narratives in order to infer temporal ordering and frequency distribution of NDE features. Results: Our analyses highlighted the following most frequently reported sequence of consecutive NDE features: Out-of-Body Experience, Experiencing a tunnel, Seeing a bright light, Feeling of peace. Yet, this sequence was encountered in a very limited number of NDErs. Conclusion: These findings may suggest that NDEs temporality sequences can vary across NDErs. Exploring associations and relationships among features encountered during NDEs may complete the rigorous definition and scientific comprehension of the phenomenon. [less ▲]

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See detailA method for independent component graph analysis of resting-state fMRI.
Ribeiro de Paula, Demetrius; Ziegler, Erik; Abeyasinghe, P et al

in Brain and Behavior (2017), 7(3),

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See detailApplication of Qualitative Thematic Analysis to Near-Death Experiences
Cassol, Helena ULiege; Pétré, Benoît ULiege; Degrange, Sophie ULiege et al

Poster (2017, February 01)

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See detailApprentissage d'auto-hypnose/self-care en oncologie. Pour qui? Comment? Pour quel intérêt?
Charland-Verville, Vanessa ULiege; FAYMONVILLE, Marie-Elisabeth ULiege; VANHAUDENHUYSE, Audrey ULiege et al

in Psycho-Oncologie (2017), 11

Les symptômes physiques les plus fréquemment liés au cancer et à ses traitements sont la douleur, les nausées et la fatigue. Ils peuvent influencer négativement la qualité de vie. Les interventions de ... [more ▼]

Les symptômes physiques les plus fréquemment liés au cancer et à ses traitements sont la douleur, les nausées et la fatigue. Ils peuvent influencer négativement la qualité de vie. Les interventions de groupe visant l’apprentissage de l’autohypnose, associé ou non à l’autobienveillance, ont démontré l’amélioration de l’adaptation des patients oncologiques. Le but de cette revue est de relever l’efficacité de l’hypnose dans la gestion des symptômes liés à la maladie et de mieux comprendre les mécanismes de la technique. [less ▲]

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