References of "Unger, Philippe"
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See detailMultiple and Mixed Valvular Heart Diseases.
Unger, Philippe; Pibarot, Philippe; Tribouilloy, Christophe et al

in Circulation: Cardiovascular Imaging (2018), 11(8), 007862

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See detailThe clinical challenge of concomitant aortic and mitral valve stenosis.
Unger, Philippe; Lancellotti, Patrizio ULiege; de Canniere, Didier

in Acta Cardiologica (2016), 71(1), 3-6

The coexistence of mitral and aortic stenosis is not exceptional. Whereas rheumatic fever is currently plummeting in the Western countries, the incidence of degenerative disease is inversely increasing ... [more ▼]

The coexistence of mitral and aortic stenosis is not exceptional. Whereas rheumatic fever is currently plummeting in the Western countries, the incidence of degenerative disease is inversely increasing. The haemodynamic interactions which may interfere both with the usual echocardiographic parameters and with the invasive assessment may render the diagnosis difficult. The therapeutic challenges raised by this entity should not be underestimated. The increased morbidity and mortality of multivalvular surgery has to be balanced with the risk of a second operation down the line if one valvular involvement, deemed of a lesser importance, is neglected. This complex situation requires the multidisciplinary approach of a heart team involving surgeons, cardiologists, geriatrists if need be and imaging specialists. [less ▲]

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See detailMitral regurgitation after transcatheter aortic valve replacement: Does the prosthesis matter?
Unger, Philippe; Dedobbeleer, Chantal; Vanden Eynden, Frederic et al

in International Journal of Cardiology (2013)

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See detailManagement of multiple valve disease.
Unger, Philippe; Rosenhek, Raphael; Dedobbeleer, Chantal et al

in Heart (2011), 97(4), 272-7

Multivalvular heart disease is not an uncommon situation, but the paucity of data for each specific situation does not allow the proposal of a standardised, evidence-based management strategy. This paper ... [more ▼]

Multivalvular heart disease is not an uncommon situation, but the paucity of data for each specific situation does not allow the proposal of a standardised, evidence-based management strategy. This paper aims at reviewing the available evidence on the management of multivalvular disease, taking into account the interactions between different valve lesions, the diagnostic pitfalls and the strategies that should be considered in the presence of multiple valvular disease. [less ▲]

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See detailSafety of ultrasound contrast agents: "Primum non nocere"?
Cosyns, Bernard; Pasquet, Agnes; Van Camp, Guy et al

in Acta Cardiologica (2009), 64(4), 547-52

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See detailEffects of valve replacement for aortic stenosis on mitral regurgitation.
Unger, Philippe; Plein, Daniele; Van Camp, Guy et al

in American Journal of Cardiology (2008), 102(10), 1378-82

We aimed to prospectively and quantitatively assess the effects of aortic valve replacement (AVR) for aortic stenosis (AS) on mitral regurgitation (MR) and to examine the determinants of the changes in MR ... [more ▼]

We aimed to prospectively and quantitatively assess the effects of aortic valve replacement (AVR) for aortic stenosis (AS) on mitral regurgitation (MR) and to examine the determinants of the changes in MR. Fifty-two patients with AS scheduled for AVR were included if holosystolic MR not being considered for replacement or repair was detected. MR was quantified using the proximal isovelocity surface area method before and 8 +/- 4 days after surgery. Mitral valvular deformation parameters did not change significantly, but the mitral effective regurgitant orifice (ERO) and regurgitant volume decreased from 11 +/- 6 mm(2) to 8 +/- 6 mm(2) and from 20 +/- 10 ml to 11 +/- 9 ml, respectively (both p <0.0001). Using multiple linear regression analysis, preoperative severity of MR, mitral leaflet coaptation height, and end-diastolic volume decrease were independently associated with postoperative reduction in MR, whereas changes in mitral valve morphology after surgery were not. MR etiology did not predict the reduction in MR. In conclusion, the decrease in MR observed in most patients after AVR is associated with the magnitude of acute left ventricular reverse remodeling. As the reduction in left ventricular systolic pressure contributes to the decrease in regurgitant volume, the preoperative quantitative assessment of MR should best be performed by measurement of the ERO. [less ▲]

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