References of "Toppets, Vinciane"
     in
Bookmark and Share    
See detailLa microscopie virtuelle
Pesesse, Laurence ULiege; Weatherspoon, Alodie ULiege; Defaweux, Valérie ULiege et al

Conference (2017, November 23)

La microscopie virtuelle fait partie intégrante des activités d'enseignement de l'Histologie et de l’Histopathologie Humaine et Animale que ce soit lors de travaux pratiques en présentiel, à distance ... [more ▼]

La microscopie virtuelle fait partie intégrante des activités d'enseignement de l'Histologie et de l’Histopathologie Humaine et Animale que ce soit lors de travaux pratiques en présentiel, à distance, dans l'animation d'un MOOC ou encore lors de cours théoriques ex-cathedra. L'interface web de Cytomine permet de donner la parole aux lames de tissus digitalisés en y associant un langage, qu'il soit descriptif sous forme d'annotations, didactique par le biais d'explications liant structure et fonctions, interrogatif en y associant des questions ou sous la forme d'un dialogue grâce au partage possible avec d'autres utilisateurs. Différents scénarios d'apprentissage élaborés par la Faculté de Médecine et de Médecine Vétérinaire vous exposeront les atouts de la microscopie virtuelle et comment celle-ci est devenue un outil incontournable de travail actif et collaboratif. [less ▲]

Detailed reference viewed: 19 (4 ULiège)
Full Text
Peer Reviewed
See detailMechanoreceptors in the anterior horn of the equine medial meniscus: an immunohistochemical approach
Nemery, Elodie ULiege; Gabriel, Annick ULiege; Grulke, Sigrid ULiege et al

in Anatomia, Histologia, Embryologia (2016), 45

Lameness due to stifle and especially meniscal lesions is frequent in equine species. In humans, mechanoreceptors involved in proprioceptive function are well studied. Given the high incidence of meniscal ... [more ▼]

Lameness due to stifle and especially meniscal lesions is frequent in equine species. In humans, mechanoreceptors involved in proprioceptive function are well studied. Given the high incidence of meniscal injuries in horses, and the lack of information concerning them in equine menisci, our objective was to study these corpuscles in six healthy anterior horns of the equine medial meniscus, which is the most common localisation reported for equine meniscal injuries. Immunohistochemical stainings were performed using antibodies against high molecular weight neurofilaments and glial fibrillary acidic proteins. From a purely fundamental point of view, our work highlights for the first time the presence of Ruffini, Pacini and Golgi corpuscles in equine meniscus. They were found, isolated or in clusters and always located at the vicinity of blood vessels, at the level of the anterior horn of the equine medial meniscus. This morphological approach could serve as a basis for clinical studies, to evaluate the impact of these corpuscles on the poor sportive prognosis in equine meniscal tears. [less ▲]

Detailed reference viewed: 39 (23 ULiège)
See detailFormasup - Portfolio professionnel
Toppets, Vinciane ULiege

Master's dissertation (2014)

Detailed reference viewed: 8 (1 ULiège)
See detailMechanoreceptors in the anterior horn of the equine medial meniscus: an immunohistochemical approach.
Nemery, Elodie ULiege; Gabriel, Annick ULiege; Grulke, Sigrid ULiege et al

Poster (2014)

Mechanoreceptors are “encapsulated sensory end-organs” involved in proprioceptive function. Given the high incidence of meniscal injuries in horses, the clinical interest in these mechanoreceptors ... [more ▼]

Mechanoreceptors are “encapsulated sensory end-organs” involved in proprioceptive function. Given the high incidence of meniscal injuries in horses, the clinical interest in these mechanoreceptors, particularly in the meniscus, and the lack of information concerning them in equine menisci, our objective was to study these corpuscles in the anterior horn of the equine medial meniscus, which is the most common localization reported for equine meniscal injuries. An immunohistochemical approach to detect Schwann cells and nerve fibres allowed us to localize and identify these corpuscles within the meniscus. Three types of mechanoreceptors were identified and localized between the abaxial quarter and the abaxial third of the meniscus: the Ruffini, Pacini and Golgi corpuscles. In conclusion, from a purely fundamental point of view, our work highlights for the first time the presence of MCR at the level of the anterior horn of the equine medial meniscus and proposes a classification based on specific immunocytochemical techniques. This morphological approach could serve as a basis for clinical studies, in order to evaluate the impact of these corpuscles on the poor sportive prognosis in equine meniscal tears. [less ▲]

Detailed reference viewed: 87 (25 ULiège)
Full Text
Peer Reviewed
See detailThree-dimensional reconstruction of the pharyngeal tonsil innervation pattern in sheep
Toppets, Vinciane ULiege; Piret, Joëlle ULiege; Gabriel, Annick ULiege et al

in Journal of Neuroimmunology (2013), (262), 79-84

Detailed reference viewed: 35 (9 ULiège)
Full Text
Peer Reviewed
See detailNeuroimmune connections in ovine pharyngeal tonsil: potential site for prion neuroinvasion
Toppets, Vinciane ULiege; Piret, Joëlle ULiege; Kirschvink, Nathalie et al

in Cell & Tissue Research (2012), 348

Recent studies have proved the possible implication of nasal associated lymphoid tissues, mainly the pharyngeal tonsil, in prion pathogenesis. However, the mechanisms of this neuroinvasion are still being ... [more ▼]

Recent studies have proved the possible implication of nasal associated lymphoid tissues, mainly the pharyngeal tonsil, in prion pathogenesis. However, the mechanisms of this neuroinvasion are still being debated. To determine the potential sites for prion neuroinvasion inside the ovine pharyngeal tonsil, the topography of neurofilaments heavy (200 kDa) (NFH), neurofilaments light (70 kDa) (NFL) and glial fibrillar acidic protein (GFAP) was semi-quantitatively analysed inside the different compartments of the tonsil. The results showed that the most innervated areas were the interfollicular area and the connective tissue located beneath the respiratory epithelium. Even if the germinal centre of the lymphoid follicles was poorly innervated, the existence of rare follicular dendritic cell-nerve synapses inside the germinal centre indicates that this mechanism of neuroinvasion is possible but unlikely to be unique. The host PRNP genotype did not influence the pattern of innervation in these different tonsil compartments, unlike age: an increase of nerve endings in a zone of high trafficking cells beneath the respiratory epithelium occurred with ageing. A minimal age-related increase of innervation inside the lymphoid follicles was also observed. An increase in nerve fibre density around the lymphoid follicles, in an area rich in mobile cells able to transport PrPd, could ensure a more efficient infectivity, not in the early phase but in the advanced phase of lymphoinvasion after amplification of PrPd, or could act as direct site of entry during neuroinvasion. [less ▲]

Detailed reference viewed: 32 (6 ULiège)
Full Text
Peer Reviewed
See detailFeatures of follicular dendritic cells in ovine pharyngeal tonsil: An in vivo and in vitro study in the context of scrapie pathogenesis
Toppets, Vinciane ULiege; Defaweux, Valérie ULiege; Piret, Joëlle ULiege et al

in Veterinary Immunology and Immunopathology (2011), 141

Although the alimentary tract has been suggested as the most likely portal of entry in natural scrapie, a growing amount of data indicates that the respiratory system and more specifically the pharyngeal ... [more ▼]

Although the alimentary tract has been suggested as the most likely portal of entry in natural scrapie, a growing amount of data indicates that the respiratory system and more specifically the pharyngeal tonsils serve as a natural portal of entry for scrapie. This study describes for the first time the broad cell populations in the lymphoid compartment of pharyngeal tonsils and more specifically inside the lymphoid follicles where the scrapie agent accumulates during the period of latency. Follicular dendritic cells (FDCs), stromal cells located in the light zone of the germinal centre of lymphoid follicles, seem to be the principal causal factor in the accumulation of the infectious agent in transmissible spongiform encephalopathy (TSE) diseases. Knowing that efficient lymphoreticular prion propagation requires PrPc expression, we analysed the expression of PrPc with the mouse monoclonal antibody Pri 909 both in situ and on FDC-cluster-enriched cell suspensions. In situ, a positive staining was observed in the germinal centre of pharyngeal lymph follicles. The germinal centre labelling was due to the presence of a follicular dendritic network as revealed after immunogold staining of isolated FDC clusters. Our results suggest that the pharyngeal lymphoreticular system and more specifically PrPc expressing follicular dendritic cells could serve as a prion “reservoir” during the latency phase, thus playing a key role during the scrapie lymphoinvasion. [less ▲]

Detailed reference viewed: 36 (7 ULiège)
Full Text
Peer Reviewed
See detailGerminal centre innervation of bovine and human tonsils related to prion diseases.
Defaweux, Valérie ULiege; Dorban, Gauthier; Antoine, Nadine ULiege et al

in Brain, Behavior & Immunity (2009), 23(1), 10

Detailed reference viewed: 30 (8 ULiège)
Peer Reviewed
See detailDo tonsilar FDCs express PrPc in sheep?
Toppets, Vinciane ULiege; Piret,J; Minne,M et al

Poster (2007, October)

Detailed reference viewed: 14 (6 ULiège)
Full Text
Peer Reviewed
See detailAre CNA42 and FDC-B1 directed against ovine follicular dendritic cells?
Toppets, Vinciane ULiege; Piret,J; Minne , M et al

Poster (2006, October)

Detailed reference viewed: 12 (6 ULiège)
Full Text
See detailMorphometric study of the equine fetlock and coffin joints
Riccio, Barbara; Carstanjen, Bianca; Denoix, Jean-Marie et al

in Italian Journal of Anatomy and Embryology (2006), 111

Detailed reference viewed: 11 (3 ULiège)