References of "Thomassin, Jean-Michel"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailCO2-sourced polycarbonates as solid electrolytes for room temperature operation lithium battery
Ouhib, Farid; Meabe, Leire; Mahmoud, Abdelfattah ULiege et al

in Journal of Materials Chemistry A (2019), 7(16), 9844-9853

In the last years, polycarbonates have been identified as alternatives to poly(ethylene oxide) as polymer electrolytes for lithium battery applications. In this work, we show the design of CO2-sourced ... [more ▼]

In the last years, polycarbonates have been identified as alternatives to poly(ethylene oxide) as polymer electrolytes for lithium battery applications. In this work, we show the design of CO2-sourced polycarbonates for its use in a room temperature lithium battery. Novel functional polycarbonates alternating oxo-carbonate moieties and polyethylene oxide segments are synthesized by the facile room temperature (rt) organocatalyzed polyaddition of CO2-sourced bis(?-alkylidene carbonate)s (bis-?CCs) with polyethylene oxide diols. The effect of the polyethylene oxide molar mass on the ionic conductivity and on the thermal properties of the poly(oxo-carbonate)s is investigated. The best candidate shows a low glass temperature of -44°C and a high ionic conductivity of 3.75 * 10-5 S cm-1 at rt when loaded with 30 wt% bis(trifluoromethanesulfonyl)imide salt (LiTFSI) without any solvent. All solid semi-interpenetrated network polymer electrolyte (SIN-SPE) is then fabricated by UV-cross-linking of a mixture containing a specifically designed poly(oxo-carbonate) bearing methacrylate pendants, diethylene glycol diacrylate and the previously described poly(oxo-carbonate) containing LiTFSI. The resulting self-standing membrane exhibits a high oxidation stability up to 5 V (vs Li/Li+), an ionic conductivity of 1.1 * 10-5 S cm-1 at rt (10-4 S cm-1 at 60°C) and promising mechanical properties. Assembled in a half cell configuration with LiFePO4 (LFP) as cathode and lithium as anode, the all-solid cell delivers a discharge capacity of 161 mAh g-1 at 0.1C and 60°C, which is very close to the theoretical capacity of LFP (170 mAh g-1). Also, a stable reversible cycling capacity over 400 cycles with high coulombic efficiency of 99 % is noted at 1C. Similar results are obtained at rt provided that 10 wt% of tetraglyme as plastisizer were added to SIN-SPE. I. [less ▲]

Detailed reference viewed: 43 (17 ULiège)
Full Text
Peer Reviewed
See detailPhoto-cross-linkable coumarin-based poly(ϵ-caprolactone) for light-controlled design and reconfiguration of shape-memory polymer networks
Defize, Thomas; Thomassin, Jean-Michel ULiege; Ottevaere, Heidi et al

in Macromolecules (2019), 52(2), 444-456

Photochemically cross-linked shape-memory polymer (SMP) materials have been achieved by functionalizing chain-ends of star-shaped poly(ϵ-caprolactone) (PCL) with 7-hydroxypropoxy-4-methylcoumarin followed ... [more ▼]

Photochemically cross-linked shape-memory polymer (SMP) materials have been achieved by functionalizing chain-ends of star-shaped poly(ϵ-caprolactone) (PCL) with 7-hydroxypropoxy-4-methylcoumarin followed by photodimerization of these end-groups. The kinetics of the network formation in function of the photosensitizer concentration has been studied by swelling experiments and rheology. Thanks to the design of a dedicated homemade mold, highly reproducible irradiation conditions have been achieved allowing to study the network formation and properties, especially the shape-memory properties, in relation to the coumarin dimerization degree as determined by Raman spectroscopy. In optimized conditions, PCL-based SMP materials exhibiting high fixity and recovery have been achieved in remarkably short irradiation time, typically 5 min. In addition, the precise control of the network cross-link density with the irradiation time, so as the high stability of the formed networks toward temperature variations was also demonstrated allowing the fine-tuning of the network properties by the irradiation process. Finally, the reversible character of the coumarin dimerization under light irradiation of appropriate wavelength has been quantified by Raman spectroscopy. The dimer photocleavage allows the photoreconfiguration of the networks offering the ability to modify the "permanent" shape of the SMP material, while preserving the excellent shape-memory properties. © 2018 American Chemical Society. [less ▲]

Detailed reference viewed: 20 (7 ULiège)
Full Text
Peer Reviewed
See detailPoly(ionic liquid)-derived N-doped carbons with hierarchical porosity for lithium- and sodium-ion batteries
Alkarmo, Walid ULiege; Ouhib, Farid ULiege; Aqil, Abdelhafid ULiege et al

in Macromolecular Rapid Communications (2019), 40(1), 1800545

The performance of lithium‐ and sodium‐ion batteries relies notably on the accessibility to carbon electrodes of controllable porous structure and chemical composition. This work reports a facile ... [more ▼]

The performance of lithium‐ and sodium‐ion batteries relies notably on the accessibility to carbon electrodes of controllable porous structure and chemical composition. This work reports a facile synthesis of well‐defined N‐doped porous carbons (NPCs) using a poly(ionic liquid) (PIL) as precursor, and graphene oxide (GO)‐stabilized poly(methyl methacrylate) (PMMA) nanoparticles as sacrificial template. The GO‐stabilized PMMA nanoparticles are first prepared and then decorated by a thin PIL coating before carbonization. The resulting NPCs reach a satisfactory specific surface area of up to 561 m2 g−1 and a hierarchically meso‐ and macroporous structure while keeping a nitrogen content of 2.6 wt%. Such NPCs deliver a high reversible charge/discharge capacity of 1013 mA h g−1 over 200 cycles at 0.4 A g−1 for lithium‐ion batteries, and show a good capacity of 204 mA h g−1 over 100 cycles at 0.1 A g−1 for sodium‐ion batteries. [less ▲]

Detailed reference viewed: 56 (14 ULiège)
Full Text
Peer Reviewed
See detailIn situ photochemical crosslinking of hydrogel membrane for guided tissue regeneration
Chichiricco, Pauline Marie ULiege; Riva, Raphaël ULiege; Thomassin, Jean-Michel ULiege et al

in Dental Materials (2018), 34(12), 1769-1782

Periodontitis is an inflammatory disease that destroys the tooth-supporting attachment apparatus. Guided tissue regeneration (GTR) is a technique based on a bar- rier membrane designed to prevent wound ... [more ▼]

Periodontitis is an inflammatory disease that destroys the tooth-supporting attachment apparatus. Guided tissue regeneration (GTR) is a technique based on a bar- rier membrane designed to prevent wound space colonization by gingival cells. This study examined a new formulation composed of two polymers that could be photochemically cross-linked in situ into an interpenetrated polymer network (IPN) forming a hydrogel mem- brane. Methods. We synthetized and characterized silanized hydroxypropyl methylcellulose (Si- HPMC) for its cell barrier properties and methacrylated carboxymethyl chitosan (MA-CMCS) for its degradable backbone to use in IPN. Hydrogel membranes were cross-linked using riboflavin photoinitiator and a dentistry visible light lamp. The biomaterial’s physicochem- ical and mechanical properties were determined. Hydrogel membrane degradation was evaluated in lysozyme. Cytocompatibility was estimated by neutral red uptake. The cell bar- rier property was studied culturing human primary gingival fibroblasts or human gingival explants on membrane and analyzed with confocal microscopy and histological staining. Results. The IPN hydrogel membrane was obtained after 120 s of irradiation. The IPN showed a synergistic increase in Young moduli compared with the single networks. The CMCS addition in IPN allows a progressive weight loss compared to each polymer network. Cyto- compatibility was confirmed by neutral red assay. Human cell invasion was prevented by hydrogel membranes and histological sections revealed that the biomaterial exhibited a barrier effect in contact with soft gingival tissue. [less ▲]

Detailed reference viewed: 38 (7 ULiège)
Full Text
Peer Reviewed
See detailCatechol containing polyhydroxyurethanes as high-performance coatings and adhesives
Panchireddy, Satyannarayana ULiege; Grignard, Bruno ULiege; Thomassin, Jean-Michel ULiege et al

in ACS Sustainable Chemistry and Engineering (2018), 6(11), 14936-14944

Green routes for the synthesis of high-performance isocyanate-free polyurethane coatings and adhesives are intensively searched for. In this article, we report a solvent- and isocyanate-free formulation ... [more ▼]

Green routes for the synthesis of high-performance isocyanate-free polyurethane coatings and adhesives are intensively searched for. In this article, we report a solvent- and isocyanate-free formulation for novel poly(hydroxyurethane) glues bearing strongly adherent catechol groups. These adhesives are prepared by the polyaddition of a CO2-sourced tricyclic carbonate, hexamethylene diamine, and a catecholamine (dopamine). The role of the catechol functions on the PHU curing and on the final PHU properties are investigated. Although the dopamine slows down the curing of the formulation, this catecholamine added at only 3.9 mol % impressively improves the mechanical and adhesion performances of PHU. The lap shear adhesion of our product surpasses those of PHU that do not contain the catechols. We also demonstrate that the catechol-bearing PHU glues are competing with the adhesion performances of commercial PU glues, at least when a thermal curing is implemented to overcome the low reactivity of cyclic carbonate with amines. The use of renewable feedstocks, the solvent-free process, the atom economy polyaddition reaction, and the absence of any toxic reagent benefit the sustainability of the final product. [less ▲]

Detailed reference viewed: 35 (4 ULiège)
See detailDesign of reprocessable poly(ε-caprolactone)-based shape-memory materials by reversible tad chemistry
Riva, Raphaël ULiege; Defize, Thomas; Alexandre, Michaël et al

Poster (2018, October 03)

Detailed reference viewed: 32 (5 ULiège)
See detailTargeting the SDF-1α/CXR4 signalling axis for the trapping of glioblastoma cells
Haji Mansor, Muhammad; Najberg, Mathie; Thomassin, Jean-Michel ULiege et al

Conference (2018, September 28)

Detailed reference viewed: 22 (2 ULiège)
See detailFunctionalized polymeric implants for trapping of glioblastoma cells
Haji Mansor, Muhammad; Najberg, Mathie; Thomassin, Jean-Michel ULiege et al

Poster (2018, September 09)

Detailed reference viewed: 24 (1 ULiège)
See detailSustainable poly(hydroxyurethane)s thermoset adhesives for affixing metals
Panchireddy, Satyannarayana ULiege; Grignard, Bruno ULiege; Thomassin, Jean-Michel ULiege et al

Poster (2018, June 20)

In the last five years, isocyanates-free polyhydroxyurethanes (PHUs), synthesized by step-growth polymerization between bis-cyclic carbonates and di- or poly-amines, have emerged as a novel class of ... [more ▼]

In the last five years, isocyanates-free polyhydroxyurethanes (PHUs), synthesized by step-growth polymerization between bis-cyclic carbonates and di- or poly-amines, have emerged as a novel class of polyurethanes (PUs). These PHUs find promising applications in flooring, paints, as thermoset materials or (thermal insulation) foams. PHUs can be also exploited advantageously for designing the next generation of high performance polyurethane adhesives. Thanks to the presence of pendant hydroxyl groups favoring the polymer/substrate interactions, the adhesion performances of PHUs may equal or even surpass the ones of conventional PUs. In this contribution, we focused on the design of novel reinforced bio- and CO2-based PHU thermosets adhesives with high shear adhesion strength for metal substrates (aluminum and stainless steel). The research included: The synthesis of a library of bi- or multifunctional 5-membered cyclic carbonates by coupling CO2 with (bio-based) epoxidized precursors using a novel home-made binary organocatalyst highly performant under very mild experimental conditions. The development of solvent-free reinforced PHU thermoset adhesives from various cyclic carbonate/amine/functional fillers formulations. For all formulations, curing kinetics was monitored by rheology to determine the gelation time and the thermo-mechanical and physico-chemical properties of PHUs were evaluated on free-standing films. The evaluation of the adhesives performances for metal sticking: The adhesion of (reinforced) PHUs onto Al-2024-T3 or stainless steel substrates was evaluated by standard cross-cut adhesion (5B) and MEK double rubber (>300) tests and shear adhesion strength (>16 MPa). [less ▲]

Detailed reference viewed: 23 (2 ULiège)
See detailSustainable poly(hydroxyurethane)s thermoset adhesives for affixing metals
Panchireddy, Satyannarayana ULiege; Grignard, Bruno ULiege; Thomassin, Jean-Michel ULiege et al

Conference (2018, June 18)

In the last 5 years, isocyanates-free polyhydroxyurethanes (PHUs), synthesized by step-growth polymerization between biscyclic carbonates and di- or poly-amines, have emerged as a novel class of ... [more ▼]

In the last 5 years, isocyanates-free polyhydroxyurethanes (PHUs), synthesized by step-growth polymerization between biscyclic carbonates and di- or poly-amines, have emerged as a novel class of polyurethanes (PUs). These PHUs find promising applications in flooring, paints, as thermoset materials or (thermal insulation) foams. PHUs can be also exploited advantageously for designing the next generation of high performance polyurethane adhesives. Thanks to the presence of pendant hydroxyl groups favouring the polymer/substrate interactions, the adhesion performances of PHUs may equal or even surpass the ones of conventional PUs. In this contribution, we focused on the design of novel reinforced bio- and CO2-based PHU thermosets adhesives with high shear adhesion strength for metal substrates (aluminium and stainless steel). [less ▲]

Detailed reference viewed: 14 (4 ULiège)
See detailFunctionalized polymeric implants for trapping of glioblastoma cells
Haji Mansor, Muhammad; Najberg, Mathie; Thomassin, Jean-Michel ULiege et al

Conference (2018, June 14)

Detailed reference viewed: 41 (7 ULiège)
See detailPhoto-crosslinkable hydrogel for guided periodontal tissue regeneration
Chichiricco, Pauline Marie ULiege; Riva, Raphaël ULiege; Thomassin, Jean-Michel ULiege et al

Conference (2018, May 29)

Periodontitis is an inflammatory disease which destroys the tooth-supporting attachment apparatus. Guided Tissue Regeneration (GTR) is a technique based on a barrier membrane designed to prevent the wound ... [more ▼]

Periodontitis is an inflammatory disease which destroys the tooth-supporting attachment apparatus. Guided Tissue Regeneration (GTR) is a technique based on a barrier membrane designed to prevent the wound space colonization by gingival cells. Indeed, these cells, characterized by a faster migration and proliferation rate compared to bone and periodontal ligament cells, could interfere with the regeneration process. In this work, we developed a liquid formulation composed of a mixture of silanized hydroxypropylmethyl cellulose (Si-HPMC) and methacrylated carboxymethyl chitosan (MA-CMCS) able to be photochemically crosslinked in situ leading to hydrogel membrane made of an interpenetrated polymer network (IPN) with a synergistic combination of favorable properties of each polymer network. Si-HPMC was selected to assess the barrier effect against soft tissue gingival invasion and CMCS to control the membrane degradation due to its degradable backbone. The methacrylate grafted chains on CMCS allows a photo-curing in short time using visible light lamp (λ 420-480 nm) already used in dentistry and when vitamin B2 (or riboflavin) is used as photoinitiator. The gel point of the IPN precursor formulation was assessed by rheological measurement under lamp irradiation. Mechanical properties after photocrosslinking were studied. Hydrogel membrane degradation was evaluated by soaking hydrogels in 10 mg/ml lysozyme buffer at 37 °C, which confirmed that the addition of CMCS modified the degradation profile of Si-HPMC hydrogel, as evidenced by the recorded weight loss. The in vitro cytocompatibility was evaluated by neutral red uptake using murine fibroblast (L929) in accordance to ISO 10993-5 specifications. Finally, we studied the barrier effect by culturing human primary gingival fibroblasts or human gingival explants on top of the membrane. Cell infiltration was analyzed with confocal microscopy and histological staining (hematoxylin, eosin Y and safranin (HES)). In the next future, in vivo experiment will be performed to further characterize the material for periodontal regeneration. [less ▲]

Detailed reference viewed: 16 (2 ULiège)
See detailFunctionalized polymeric implants for trapping of glioblastome cells
Haji Mansor, Muhamad; Najberg, Mathie; Thomassin, Jean-Michel ULiege et al

Poster (2018, May 28)

Detailed reference viewed: 22 (3 ULiège)
See detailSynthesis of polyvinylalcohol bearing catechol for hydrogel formation
Bourguignon, Maxime ULiege; Thomassin, Jean-Michel ULiege; Jérôme, Christine ULiege et al

Poster (2018, May 28)

Polyvinylalcohol (PVA) is one of the most produced and used polymer thanks to its special properties like its hydrophilicity, water solubility and good mechanical resistance. In this way, PVA is of ... [more ▼]

Polyvinylalcohol (PVA) is one of the most produced and used polymer thanks to its special properties like its hydrophilicity, water solubility and good mechanical resistance. In this way, PVA is of primary importance for the development of a wide range of applications in adhesive, food industry and biomedical application. This water-soluble polymer is particularly suited for the Hydrogel formation that require strong cross-linking between polymer chains to avoid solubilization. There is little way to post-modify polyvinyl alcohol to obtain good hydrogel: physical method like freeze thaw and chemical crosslinked by glutaraldehyde are the most commonly used. In a bioinspired approach, we synthesized a mussel-inspired PVA by a condensation reaction between an aldehyde bearing catechol and two adjacent OH groups of PVA. It has been showed that catechols play an important role in mussel anchorage due to their versatile binding capacity to diverse substrate. They are also able to react with each other and are responsible of strong cohesion between mussel feet protein. For this reason the catechol induce reticulation can be used for hydrogel formation. However acetal formation is well known to be an equilibrate reaction which needs dry organic condition to fully proceed. Nevertheless, It has been commercially used for the transformation of PVA to produce polyvinylbutyral and polyvinyl formal for glass factory. By extending this type of reaction, we succeed to produce the catechol-modified PVA in a water process. As other polyvinyl acetal, obtained polymer is not water-soluble and strategies to disperse the polymer in solution were presented. Finally gel properties of produce hydrogel were presented [less ▲]

Detailed reference viewed: 48 (3 ULiège)
See detailFunctionalized polymeric implants for controlling the migration of glioblastoma cells and their subsequent trapping
Haji-Mansor, Muhammad; Najberg, Mathie; Thomassin, Jean-Michel ULiege et al

Conference (2018, April 16)

Detailed reference viewed: 20 (4 ULiège)
Full Text
Peer Reviewed
See detailContinuous-porous N-doped carbon network as high-performance electrode for lithium-ion batteries
Alkarmo, Walid ULiege; Ouhib, Farid ULiege; Aqil, Abdelhafid ULiege et al

in Journal of Materials Science (2018), 53(8), 6135-6146

Hierarchical porous N-doped carbon (NPC) is prepared by pyrolysis of poly(- methyl methacrylate) (PMMA) particles decorated by graphene oxide (GO) and polypyrrole (PPy) as precursors and used as anode for ... [more ▼]

Hierarchical porous N-doped carbon (NPC) is prepared by pyrolysis of poly(- methyl methacrylate) (PMMA) particles decorated by graphene oxide (GO) and polypyrrole (PPy) as precursors and used as anode for lithium-ion batteries. The composite precursors with different diameter and composition (PMMA/GO/ PPy-A and B) were conveniently prepared by dispersion polymerization of methyl methacrylate in the presence of graphene oxide as stabilizer in aqueous medium, followed by addition of pyrrole and its oxidative polymerization. After pyrolysis, the resulting NPC composites with hierarchically structured macro- and mesopores exhibit high surface area (289–398 m2/g) and different N-doping levels (7.46 and 4.22 wt% of nitrogen content). The NPC with the highest N-doping level (7.46 wt%) shows high reversible capacities of 831 mAh/g at 74.4 mA/g (C/5) after 50 cycles and excellent rate performances. [less ▲]

Detailed reference viewed: 72 (26 ULiège)
Full Text
Peer Reviewed
See detailSpontaneous atopic dermatitis due to immune dysregulation in mice lacking Adamts2 and 14.
Dupont, Laura ULiege; Ehx, Grégory; Chantry, Mathilde et al

in Matrix Biology (2018), 70

Since its first description, ADAMTS14 has been considered as an aminoprocollagen peptidase based on its high similarity with ADAMTS3 and ADAMTS2. As its importance for procollagen processing was never ... [more ▼]

Since its first description, ADAMTS14 has been considered as an aminoprocollagen peptidase based on its high similarity with ADAMTS3 and ADAMTS2. As its importance for procollagen processing was never experimentally demonstrated in vivo, we generated Adamts14-deficient mice. They are healthy, fertile and display normal aminoprocollagen processing. They were further crossed with Adamts2-deficient mice to evaluate potential functional redundancies between these two highly related enzymes. Initial characterizations made on young Adamts2-Adamts14-deficient animals showed the same phenotype as that of Adamts2-deficient mice, with no further reduction of procollagen processing and no significant aggravation of the structural alterations of collagen fibrils. However, when evaluated at older age, Adamts2-Adamts14-deficient mice surprisingly displayed epidermal lesions, appearing in 2 month-old males and later in some females, and then worsening rapidly. Immunohistological evaluations of skin sections around the lesions revealed thickening of the epidermis, hypercellularity in the dermis and extensive infiltration by immune cells. Additional investigations, performed on young mice before the formation of the initial lesions, revealed that the primary cause of the phenotype was not related to alterations of the epidermal barrier but was rather the result of an abnormal activation and differentiation of T lymphocytes towards a Th1 profile. However, the primary molecular defect probably does not reside in the immune system itself since irradiated Adamts2-Adamts14-deficient mice grafted with WT immune cells still developed lesions. While originally created to better characterize the common and specific functions of ADAMTS2 and ADAMTS14 in extracellular matrix and connective tissues homeostasis, the Adamts2-Adamts14-deficient mice revealed an unexpected but significant role of ADAMTS in the regulation of immune system, possibly through a cross-talk involving mesenchymal cells and the TGFβ pathways. [less ▲]

Detailed reference viewed: 29 (5 ULiège)
Full Text
Peer Reviewed
See detailBio-based poly(hydroxyurethane) glues for metal substrates
Panchireddy, Satyannarayana ULiege; Grignard, Bruno ULiege; Thomassin, Jean-Michel ULiege et al

in Polymer Chemistry (2018), 9

Bio- and CO2-based high performance thermoset poly(hydroxyurethane)s (PHUs) glues were designed from solvent- and isocyanate-free formulations based on cyclocarbonated soybean oil, diamines (aliphatic ... [more ▼]

Bio- and CO2-based high performance thermoset poly(hydroxyurethane)s (PHUs) glues were designed from solvent- and isocyanate-free formulations based on cyclocarbonated soybean oil, diamines (aliphatic, cycloaliphatic or aromatic) and functional silica or ZnO fillers. Shear strength values and cohesive or adhesive failure of glues was correlated with the crosslinking, mechanical and thermal properties of the nanocomposite PHU thermosets. The addition of SiO2 or ZnO fillers bearing cyclic carbonate groups at their surface enabled to strongly improve the adhesion performances of the glues up to 173% compared to the unfilled PHUs. The most performant reinforced PHU adhesives showed a shear strength up to 11.3 MPa for aluminum substrate, and 10.1 MPa for stainless steel with cohesive failure. This study highlights that bio-based nanocomposite PHU thermosets are promising sustainable alternatives to conventional glues made of toxic formulations containing [less ▲]

Detailed reference viewed: 38 (14 ULiège)