References of "TONGLET, Martin"
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See detailmTICCS and its inter-rater reliability to predict the need for massive transfusion in severely injured patients
Horst, K.; Lichte, P.; Bläsius, F. et al

in European Journal of Trauma and Emergency Surgery (2020)

Purpose: The modified Trauma-Induced Coagulopathy Clinical Score (mTICCS) presents a new scoring system for the early detection of the need for a massive transfusion (MT). This easily applicable score was ... [more ▼]

Purpose: The modified Trauma-Induced Coagulopathy Clinical Score (mTICCS) presents a new scoring system for the early detection of the need for a massive transfusion (MT). This easily applicable score was validated in a large trauma cohort and proven comparable to more established complex scoring systems. However, the inter-rater reliability of the mTICCS has not yet been investigated. Methods: Therefore, a dataset of 15 randomly selected and severely injured patients (ISS ≥ 16) derived from the database of a level I trauma centre (2010–2015) was used. Moreover, 15 severely injured subjects that received MT were chosen from the same databank. A web-based survey was sent to medical professionals working in the field of trauma care asking them to evaluate each patient using the mTICCS. Results: In total, 16 raters (9 residents and 7 specialists) completed the survey. Ratings from 15 medical professionals could be evaluated and led to an ICC of 0.7587 (95% Bootstrap confidence interval (BCI) 0.7149–0.8283). A comparison of working experience specific ICC (n = 7 specialists, ICC: 0.7558, BCI: 0.7076–0.8270; n = 8 residents, ICC: 0.7634, BCI: 0.7183–0.8335) showed no significant difference between the two groups (p = 0.67). Conclusion: In summary, reliability values need to be considered when making clinical decisions based on scoring systems. Due to its easy applicability and its almost perfect inter-rater reliability, even with non-specialists, the mTICCS might therefore be a useful tool to predict the early need for MT in multiple trauma. © 2020, The Author(s). [less ▲]

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See detailImpact of a prehospital discrimination between trauma patients with or without early acute coagulopathy of trauma and the need for damage control resuscitation: rationale and design of a multicenter randomized phase II trial.
TONGLET, Martin ULiege; D'ORIO, Vincenzo ULiege; MOENS, Didier ULiege et al

in Acta Chirurgica Belgica (2019)

BACKGROUND: The evidence of the Trauma Induced Coagulopathy Clinical Score (TICCS) accuracy has been evaluated in several studies but the potential effect of its use on patient outcomes needs to be ... [more ▼]

BACKGROUND: The evidence of the Trauma Induced Coagulopathy Clinical Score (TICCS) accuracy has been evaluated in several studies but the potential effect of its use on patient outcomes needs to be evaluated. The primary objective of this study is to evaluate the impact on mortality of a prehospital discrimination between trauma patients with or without a potential need for damage control resuscitation. METHODS: The trial will be designed as randomized phase II clinical trial with comparison of the experimental protocol against the standard of care. The TICCS will be calculated on the site of injury for the patients of the intervention group and treatment will be guided by the TICCS value. Seven days mortality, 30 days mortality, global use of blood products and global hospital length-of-stay will be compared. DISCUSSION: Many data suggest that a very early flagging of trauma patients in need for DCR would be beneficial but this need to be proved. Do we improve our quality of care by an earlier diagnosis? Does a prehospital discrimination between trauma patients with or without a potential need for DCR has a positive impact? [less ▲]

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See detailThromboelastometry in trauma care: a place in the 2018 Belgian health care system?
TONGLET, Martin ULiege; Poplavsky, Jean Louis; SEIDEL, Laurence ULiege et al

in Acta Clinica Belgica (2018)

Introduction Evidence supporting the use of Thromboelastography (TEG®) and rotational thromboelastometric (ROTEM®) in the trauma setting remains limited. We present the results of a practical evaluation ... [more ▼]

Introduction Evidence supporting the use of Thromboelastography (TEG®) and rotational thromboelastometric (ROTEM®) in the trauma setting remains limited. We present the results of a practical evaluation of the potential interest of ROTEM® in the diagnosis of acute coagulopathy and the need for emergent blood product transfusion in the general trauma population of a non-trauma Belgian emergency department. Methods Extracting a convenience cohort from the initial prospective TICCS study, we performed a retrospective analysis to test the following hypothesis: ROTEM® might be helpful to discriminate trauma patients with or without acute coagulopathy. Fifty patients were included and ROTEM® results were compared to conventional coagulation tests results, blood transfusion need and outcome. Results With a negative predictive value of 97.6% and a positive predictive value of 42.9%, a strictly normal ROTEM® profile at the time of admission seems to be able to exclude the presence of acute coagulopathy. ROTEM® also seems to be accurate in identifying patients without the need for emergent blood product transfusions. Conclusion In a population of trauma patients of a Belgian general emergency department, a strictly normal coagulation profile evaluated by ROTEM® at hospital entry is associated with a normal coagulation profile evaluated by INR and fibrinogen levels and the absence of any indication of blood product transfusion. ROTEM® may be useful for preselection of trauma patients at risk for coagulopathy within the global trauma population. This, however, would need confirmation in further investigations. [less ▲]

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See detailPre-hospital transfusion of red blood cells in civilian trauma patients: what's next?
TONGLET, Martin ULiege; SWERTS, Frédéric ULiege; Mathonet, Pierre-Yves ULiege et al

in Transfusion Medicine (2018), 28(6), 457

[No abstract available]

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See detailLe cas clinique du mois. Une cause rare de lapararotomie exploratrice negative chez le polytraumatise.
Demesmaker, Vincent ULiege; ANCION, Aurore ULiege; SWERTS, Frédéric ULiege et al

in Revue Médicale de Liège (2018), 73(1), 7-9

We report the case of a young man involved in a high velocity road traffic accident. He presented with multiple injuries and a shock. This shock was suspected to be caused by an intra-abdominal bleeding ... [more ▼]

We report the case of a young man involved in a high velocity road traffic accident. He presented with multiple injuries and a shock. This shock was suspected to be caused by an intra-abdominal bleeding and an exploratory laparotomy was performed. The procedure did not identify any intra-abdominal bleeding and the source of bleeding was found lately: an intramuscular active bleeding in the dorsal and lumbar muscular compartments. This case was discussed in our local mortality and morbidity meeting. [less ▲]

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See detailEarly identification of trauma patients in need for emergent transfusion: results of a single-center retrospective study evaluating three scoring systems.
SWERTS, Frédéric ULiege; MATHONET, Pierre-Yves ULiege; Ghuysen, Alexandre ULiege et al

in European Journal of Trauma and Emergency Surgery (2018)

BACKGROUND: The Trauma-Induced Coagulopathy Clinical Score (TICCS) was developed to be calculable on the site of injury to discriminate between trauma patients with or without the need for damage control ... [more ▼]

BACKGROUND: The Trauma-Induced Coagulopathy Clinical Score (TICCS) was developed to be calculable on the site of injury to discriminate between trauma patients with or without the need for damage control resuscitation and thus transfusion. This early alert could then be translated to in-hospital parameters at patient arrival. Base excess (BE) and ultrasound (FAST) are known to be predictive parameters for emergent transfusion. We emphasize that adding these two parameters to the TICCS could improve the scoring system predictability. METHODS: A retrospective study was conducted in the University Hospital of Liege. TICCS was calculated for every patient. BE and FAST results were recorded and points were added to the TICCS according to the TICCS.BE definition (+ 3 points if BE < - 5 and + 3 points in case of a positive FAST). Emergent transfusion was defined as the use of at least one blood product in the resuscitation room. The capacity of the TICCS, the TICCS.BE and the Trauma-Associated Severe Hemorrhage (TASH) to predict emergent transfusion was assessed. RESULTS: A total of 328 patients were included. Among them, 14% needed emergent transfusion. The probability for emergent transfusion grows with the TICCS and the TICCS.BE values. We did not find a significant difference between the TICCS (AUC 0.73) and the TICCS.BE (AUC 0.76). The TASH proved to be more predictive (AUC 0.89). 66.6% of the patients with a TICCS >/= 10 and 81.5% with a TICCS.BE >/= 14 required emergent transfusion. CONCLUSION: Adding BE and FAST to the original TICCS does not significantly improve the scoring system predictability. A prehospital TICCS > 10 could be used as a trigger for emergent transfusion activation. TASH could then be used at hospital arrival. Prehospital TASH calculation may be possible but should be further investigated. LEVEL OF EVIDENCE: Diagnostic test, level III. [less ▲]

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See detailLe cas clinique du mois Une cause rare de laparotomie exploratrice négative chez le polytraumatisé
Demesmaker, Vincent; ANCION, Aurore ULiege; SWERTS, Frédéric ULiege et al

in Revue Médicale de Liège (2018), 73(1), 1-4

We report the case of a young man involved in a high velocity road traffic accident. He presented with multiple injuries and a shock. This shock was suspected to be caused by an intra-abdominal bleeding ... [more ▼]

We report the case of a young man involved in a high velocity road traffic accident. He presented with multiple injuries and a shock. This shock was suspected to be caused by an intra-abdominal bleeding and an exploratory laparotomy was performed. The procedure did not identify any intra-abdominal bleeding and the source of bleeding was found lately: an intramuscular active bleeding in the dorsal and lumbar muscular compartments. This case was discussed in our local mortality and morbidity meeting [less ▲]

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See detailTrauma pneumonectomy for major thoracic bleeding: when should we consider it ?
TONGLET, Martin ULiege; MOENS, Didier ULiege; D'ORIO, Vincenzo ULiege et al

in Journal of Trauma and Acute Care Surgery (2018)

Lettre à l'éditeur du Journal of Trauma concernant la pneumectomie totale dans le contexte d'une hémorragie thoracique incontrôlable.

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See detailFibrinolysis Shutdown in Severely Injured Trauma Patients: A New World to Explore.
TONGLET, Martin ULiege; D'ORIO, Vincenzo ULiege; GHUYSEN, Alexandre ULiege et al

in Journal of the American College of Surgeons (2017), 225(6), 831-832

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See detailPrehospital identification of trauma patients requiring transfusion: results of a retrospective study evaluating the use of the trauma induced coagulopathy clinical score (TICCS) in 33,385 patients from the TraumaRegister DGU®
TONGLET, Martin ULiege; Lefering, Rolf; Minon, Jean-Marc et al

in Acta Chirurgica Belgica (2017)

Background: Identifying trauma patients that need emergent blood product transfusion is crucial. The Trauma Induced Coagulopathy Clinical Score (TICCS) is an easy-to-measure score developed to meet this ... [more ▼]

Background: Identifying trauma patients that need emergent blood product transfusion is crucial. The Trauma Induced Coagulopathy Clinical Score (TICCS) is an easy-to-measure score developed to meet this medical need. We hypothesized that TICCS would assist in identifying patients that need a transfusion in a large cohort of severe trauma patients from the TraumaRegister DGUVR (TR-DGU). Materials and methods: A total of 33,385 severe trauma patients were extracted from the TR-DGU for retrospective analysis. The TICCS was adapted for the registry structure. Blood transfusion was defined as the use of at least one unit of red blood cells (RBC) during acute hospital treatment. Results: With an area under the receiving operating curve (AUC) of 0.700 (95% CI: 0.691–0.709), the TICCS appeared to be moderately discriminant for determining the need for RBC transfusion in the trauma population of the TR-DGU. A TICCS cut-off value of 12 yielded the best trade-off between true positives and false positives. The corresponding positive predictive value and negative predictive values were 48.4% and 89.1%, respectively. Conclusion: This retrospective study confirms that the TICCS is a useful and simple score for discriminating between trauma patients with and without the need for emergent blood product transfusion. [less ▲]

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See detailComment je traite... l'intoxication aux antidépresseurs tricycliques: Efficacité potentielle d'un traitement par émulsion lipidique
Berthe, G.; TONGLET, Martin ULiege; Bertrand, X. et al

in Revue Médicale de Liège (2017), 72(1), 6-9

Poisoning with tricyclic antidepressants is common and can be life-threatening. The classic management is well known (chelating gastrointestinal, sodium bicarbonate, benzodiazepine, norepinephrine). A few ... [more ▼]

Poisoning with tricyclic antidepressants is common and can be life-threatening. The classic management is well known (chelating gastrointestinal, sodium bicarbonate, benzodiazepine, norepinephrine). A few years ago, a treatment with lipid emulsion, previously used in local anesthetics poisoning, has been successfully tested in tricyclic poisoning with cardiac arrest. We are currently unable to explain the exact mechanism of this treatment but it could have a place in the treatment of severe tricyclic poisoning with hemodynamic instability in addition to the conventional treatment. [less ▲]

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See detailEarly prediction of on-going hemorrhage in severe trauma: presentation of the existing scoring systems.
TONGLET, Martin ULiege

in Archives of Trauma Research (2016), 5(4),

Early prediction of ongoing hemorrhage may reduce mortality via the earlier delivery of blood products, adequate orientation of the patient in a dedicated highly specialized and trained infrastructure ... [more ▼]

Early prediction of ongoing hemorrhage may reduce mortality via the earlier delivery of blood products, adequate orientation of the patient in a dedicated highly specialized and trained infrastructure, and by earlier correction of acute traumatic coagulopathy. We identified 14 scores or algorithms developed for the prediction of ongoing hemorrhage and the need for massive transfusion in severe trauma patients. [less ▲]

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See detailMassive transfusion in critical haemorrhage following trauma: Aren’t we missing something?
TONGLET, Martin ULiege

in Journal of Emergency Medicine, Trauma and Acute Care (2016), 5

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See detailPrise en charge du traumatisme grave.
TONGLET, Martin ULiege

Scientific conference (2016, May 19)

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See detailMassive bleeding following severe blunt trauma: the first minutes that can change everything.
TONGLET, Martin ULiege

in Acta Chirurgica Belgica (2016)

The first hour following a major trauma with massive bleeding is certainly the most decisive period in global trauma care. Most of it takes place during the prehospital care. Those prehospital minutes are ... [more ▼]

The first hour following a major trauma with massive bleeding is certainly the most decisive period in global trauma care. Most of it takes place during the prehospital care. Those prehospital minutes are thus determinant as they can be used to correctly identified patient’s clinical condition, initiate organization of the in-hospital needed resources and initiate specific therapies in the very early phase after trauma. Significant recent advances in this aspect of care have been made and but evidence to support some of those strategies is still lacking. [less ▲]

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See detailWhy is this urine turning blue? A uncommon alarm but a common disease.
LU, Marie Anh-Dao ULiege; GENSBURGER, Mathieu ULiege; TONGLET, Martin ULiege et al

Poster (2016, January 30)

Turning purple-blue urine is an alarming phenomenon uncommonly seen in patients with chronic urinary catheterization. Such discoloration, often misdiagnosed as haematuria, frequently causes concerns for ... [more ▼]

Turning purple-blue urine is an alarming phenomenon uncommonly seen in patients with chronic urinary catheterization. Such discoloration, often misdiagnosed as haematuria, frequently causes concerns for the nurses, the doctor, the patient and his family. [less ▲]

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See detailPrehospital Shock Index in severe trauma patients.
TONGLET, Martin ULiege

Conference (2016, January 30)

Shock Index (SI) is defined as the ratio of the Heart Rate (HR) to systolic Blood Pressure (BP). In place of HR or BP alone, SI has been used as a guide for diagnosing of acute hypovolemia, even in the ... [more ▼]

Shock Index (SI) is defined as the ratio of the Heart Rate (HR) to systolic Blood Pressure (BP). In place of HR or BP alone, SI has been used as a guide for diagnosing of acute hypovolemia, even in the presence of normal HR or BP. Pre-hospital SI also seems to correlate with mortality (1). We present here a retrospective analyze of the 82 trauma patients initially included in the study evaluating the Trauma-Induced Coagulopathy Clinical Score TICCS (2). The aim of this analyze was to determine if pre-hospital SI is correlated with acidosis and mortality. [less ▲]

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See detailDoes a 'Massive transfusion protocol' activation necessarily mean massive transfusion ?
TONGLET, Martin ULiege

Conference (2016, January 30)

We implemented in June 2013 a Massive Transfusion Protocol MTP in our institution (1). It can be activated in the presence of a hypovolemic shock associated with a proven or highly suspected hemorrhage ... [more ▼]

We implemented in June 2013 a Massive Transfusion Protocol MTP in our institution (1). It can be activated in the presence of a hypovolemic shock associated with a proven or highly suspected hemorrhage with no response to intravenous crystalloid bolus. Massive Transfusion MT is traditionally defined as the transfusion of 10 or more units of Packed Red Blood Cells PRBC within 24 hours. After MTP activation, how much blood products did we actually transfused? [less ▲]

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See detailDiagnostic de l'hyperémèse cannabinoïde : le point sur le syndrome "cannabis-douche"
CUPPENS, Benoit ULiege; GENSBURGER, Mathieu ULiege; TONGLET, Martin ULiege et al

in Revue Médicale de Liège (2016), 71(12), 541-545

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