References of "Petermans, Jean"
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See detailPrediction of adverse outcomes in nursing home residents according to intrinsic capacity proposed by the World Health Organization
Charles, Alexia ULiege; Buckinx, Fanny ULiege; Locquet, Médéa ULiege et al

in Journal of Gerontology: Series A, Biological Sciences and Medical Sciences (2020), 75(8), 1594-1599

Background: This study aimed to evaluate the predictive value of the domains of intrinsic capacity (ie, cognition, locomotion, sensory, vitality, and psychosocial) proposed by the World Health ... [more ▼]

Background: This study aimed to evaluate the predictive value of the domains of intrinsic capacity (ie, cognition, locomotion, sensory, vitality, and psychosocial) proposed by the World Health Organization (WHO) on the 3-year adverse health outcomes of nursing home residents. Methods: A 3-year incidence of mortality, falls, repeated falls, and autonomy decline (ie, a one-unit increase in the Katz score) was assessed in a cohort of Belgian nursing home residents. Cognition was assessed using the Mini-Mental State Examination (MMSE). For locomotion, balance, gait speed and chair stand performance were evaluated by the Short Physical Performance Battery test. The sensory domain was measured using the Strawbridge questionnaire for audition and vision. For vitality, abdominal circumference, body mass index, nutritional status (by Mini Nutritional Assessment [MNA]) and handgrip strength were assessed. Psychosocial status was evaluated by the EQ-5D and the Center for Epidemiological Studies Depression scale. Missing data were handled by multiple imputations. Cox proportional hazard models, logistic regressions, and analysis of variance were used for the analyses. Results: In the multivariable model, a one-unit increase in balance performance and in the nutrition score decreased the probability of death by 12% (Hazard ratio [HR] = 0.88; 95% confidence interval [CI] 0.78–0.99) and 4% (HR = 0.96; 95% CI 0.93–0.99), respectively. The risk of falling decreased when there was a one-unit increase in balance performance (HR = 0.87, 95% CI 0.79–0.96) and in the nutrition score (HR = 0.96, 95% CI 0.93–0.98). No association was found for intrinsic capacity and repeated falls. Low scores in nutrition (odds ratio = 0.86, 95% CI 0.77–0.96) were associated with a higher probability of autonomy decline. Conclusion: Some domains of intrinsic capacity predicted health outcomes among nursing home residents. Nutrition and balance should be regularly checked among this population. [less ▲]

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See detailAssessment of muscle function and physical performance in daily clinical practice: a position paper endorsed by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO).
Beaudart, Charlotte ULiege; Rolland, Y.; Cruz-Jentoft, A.J. et al

in Calcified Tissue International (2019), 105(1), 1-14

It is well recognized that poor muscle function and poor physical performance are strong predictors of clinically relevant adverse events in older people. Given the large number of approaches to measure ... [more ▼]

It is well recognized that poor muscle function and poor physical performance are strong predictors of clinically relevant adverse events in older people. Given the large number of approaches to measure muscle function and physical performance, clinicians often struggle to choose a tool that is appropriate and validated for the population of older people they deal with. In this paper, an overview of different methods available and applicable in clinical settings is proposed. This paper is based on literature reviews performed by members of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) working group on frailty and sarcopenia. Face-to-face meetings were organized afterwards where the whole group could amend and discuss the recommendations further. Several characteristics should be considered when choosing a tool: (1) purpose of the assessment (intervention, screening, diagnosis); (2) patient characteristics (population, settings, functional ability, etc.); (3) psychometric properties of the tool (test–retest reliability, inter-rater reliability, responsiveness, floor and ceiling effects, etc.); (4) applicability of the tool in clinical settings (overall cost, time required for the examination, level of training, equipment, patient acceptance, etc.); (5) prognostic reliability for relevant clinical outcomes. Based on these criteria and the available evidence, the expert group advises the use of grip strength to measure muscle strength and the use of 4-m gait speed or the Short Physical Performance Battery test to measure physical performance in daily practice. The tools proposed are relevant for the assessment of muscle weakness and physical performance. Subjects with low values should receive additional diagnostic workups to achieve a full diagnosis of the underlying condition responsible (sarcopenia, frailty or other). [less ▲]

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See detailSarcopenia : performance of the SARC-F questionnaire according to the european consensus criteria, EWGSOP1 vs. EWGSOP2
Hajaoui, Manon ULiege; Locquet, Médéa ULiege; Beaudart, Charlotte ULiege et al

in Osteoporosis International (2019, July), 30(S2), 539-540

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See detailDevelopment of a frailty specific patient reported outcome (PRO): the FRAILQOL
Buckinx, Fanny ULiege; Beaudart, Charlotte ULiege; Reginster, Jean-Yves ULiege et al

in Osteoporosis International (2019, July), 30(S2), 465-466

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See detailImpact of frailty status on the cost of drugs and dietary supplements prescribed to nursing home residents: the SENIOR cohort.
Buckinx, Fanny ULiege; Charles, Alexia ULiege; Quabron, Adrien ULiege et al

in Aging Clinical and Experimental Research (2019), 31

Background The financial impact associated with drug consumption has been poorly investigated among frail subjects and, specifically, in nursing home settings. Aims To determine the association of the ... [more ▼]

Background The financial impact associated with drug consumption has been poorly investigated among frail subjects and, specifically, in nursing home settings. Aims To determine the association of the average monthly cost of the drugs and dietary supplements consumed by nursing home residents with their frailty status. Methods This is an analysis of the first follow-up year of the SENIOR cohort. All participants were classified into “frail” or “non-frail” categories according to Fried’s criteria at baseline. Monthly bills from the pharmacy were analysed to determine the association between the average monthly cost of the drugs and dietary supplements consumed and frailty status. Results A sample of 87 residents (83.8 ± 9.33 years and 75.9% women) from the SENIOR cohort was included. The prevalence of frailty was 28%. The median number of medications consumed each day was 9 (6–12) (no difference between frail and non-frail subjects; p = 0.15). The overall median monthly cost was € 109.6, of which 49% was covered by Belgian social security and the remaining balance was paid by the patient. When comparing the drug expenses of the frail subjects and the non-frail subjects, the overall average monthly cost did not differ between the 2 groups (p = 0.057). Nevertheless, the expenditure remaining to be paid by the residents, after the Belgian social security intervention, was significantly higher among the frail residents (€ 65.7) than among the non-frail residents (€ 47.6; p = 0.017). Conclusions Frailty status has an impact on the expenditures related to the consumption of drugs. [less ▲]

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See detailEWGSOP 2 vs. EWGSOP 1: impact on the prevalence of sarcopenia and its outcomes
Locquet, Médéa ULiege; Beaudart, Charlotte ULiege; Petermans, Jean ULiege et al

in Osteoporosis International (2019), 30(S2), 275-276

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See detailIntrinsic capacity and its association with mortality over 3 years in nursing homes: Results of the SENIOR cohort
Charles, Alexia ULiege; Buckinx, Fanny ULiege; Locquet, Médéa ULiege et al

in Osteoporosis International (2019), 30(S2), 177-178

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See detailGait symmetry in the dual task condition as a predictor of future falls among independent older adults: a 2-year longitudinal study
GILLAIN, Sophie ULiege; Boutaayamou, Mohamed ULiege; Schwartz, Cédric ULiege et al

in Aging Clinical and Experimental Research (2019), 31(8), 1057-1067

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See detailUsing supervised learning machine algorithm to identify future fallers based on gait patterns: A two-year longitudinal study
Gillain, Sophie ULiege; Boutaayamou, Mohamed ULiege; Schwartz, Cédric ULiege et al

in Experimental Gerontology (2019), 127(first online),

Introduction: Given their major health consequences in the elderly, identifying people at risk of fall is a major challenge faced by clinicians. A lot of studies have confirmed the relationships between ... [more ▼]

Introduction: Given their major health consequences in the elderly, identifying people at risk of fall is a major challenge faced by clinicians. A lot of studies have confirmed the relationships between gait parameters and falls incidence. However, accurate tools to predict individual risk among independent older adults without a history of falls are lacking. Objective: This study aimed to apply a supervised learning algorithm to a data set recorded in a two-year longitudinal study, in order to build a classification tree that could discern subsequent fallers based on their gait patterns. Methods: A total of 105 adults aged >65 years, living independently at home and without a recent fall history were included in a two-year longitudinal study. All underwent physical and functional assessment. Gait speed, stride length, frequency, symmetry and regularity, and minimum toe clearance were recorded in comfortable, fast and dual task walking conditions in a standardized laboratory environment. Fall events were recorded using personal falls diaries. A supervised machine learning algorithm (J48) has been applied to the data recorded at inclusion in order to obtain a classification tree able to identify future fallers. Results: Based on fall information from 96 volunteers, a classification tree correctly identifying 80% of future fallers based on gait patterns, gender, and stiffness, was obtained, with accuracy of 84%, sensitivity of 80%, specificity of 87%, a positive predictive value of 78%, and a negative predictive value of 88%. Discussion: While the performances of the classification tree warrant further confirmation, it is the first predictive tool based on gait parameters that are identified (not clustered) allowing its use by other research teams. Conclusion: This original longitudinal pilot study using a supervised machine learning algorithm, shows that gait parameters and clinical data can be used to identify future fallers among independent older adults. © 2019 Elsevier Inc. [less ▲]

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See detailThree-Year Adverse Health Consequences of Sarcopenia in Community-Dwelling Older Adults According to 5 Diagnosis Definitions
Locquet, Médéa ULiege; Beaudart, Charlotte ULiege; Hajaoui, Manon ULiege et al

in Journal of the American Medical Directors Association (2019), 20

Objectives: To assess the occurrence of 3 major adverse outcomes of sarcopenia (ie, physical disabilities, institutionalizations and deaths) observed over a 3-year follow-up in older adults and compare ... [more ▼]

Objectives: To assess the occurrence of 3 major adverse outcomes of sarcopenia (ie, physical disabilities, institutionalizations and deaths) observed over a 3-year follow-up in older adults and compare the risk of these outcomes using 5 definitions of sarcopenia. Design: The study is a part of the ongoing SarcoPhAge (for Sarcopenia and Physical Impairment with advancing Age) longitudinal project. Setting and Participants: The SarcoPhAge study follows 534 community-dwelling older adults. Measures: Sarcopenia was defined as low muscle mass plus a decreased muscle function. Data on adverse outcomes were collected yearly during the annual follow-up or with a phone call. The association between baseline sarcopenia and the occurrence of undesirable outcomes was tested using the Cox proportional hazards model or a logistic regression model. Results: A total of 534 subjects were recruited into this prospective cohort (73.5 6.2 years, 60.5% female). After 3 years, 33 participants were lost to follow-up. If no association between baseline sarcopenia and physical disabilities or institutionalizations was highlighted, a higher number of deaths occurred in individuals diagnosed with sarcopenia than in those who were not diagnosed (16.2% vs 4.6%, P value <.001). The probability of death within 3 years when presenting with sarcopenia showed an approximately 3-fold increase compared to subjects without sarcopenia. Conclusion: Over a 3-year period, sarcopenia at baseline was associated with an increased risk of mortality. There were some variations in the ability of different definitions of sarcopenia to predict outcomes. [less ▲]

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See detailSarcopenia: Performance of the SARC-F Questionnaire According to the European Consensus Criteria, EWGSOP1 and EWGSOP2
Hajaoui, Manon; Locquet, Médéa ULiege; Beaudart, Charlotte ULiege et al

in Journal of the American Medical Directors Association (2019), 20(9), 1182-1183

[No abstract available]

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See detailNormative data for isometric strength of 8 different muscle groups and their usefulness as a predictor of loss of autonomy among physically active nursing home residents: The senior cohort
Buckinx, Fanny ULiege; Croisier, Jean-Louis ULiege; Charles, Alexia ULiege et al

in Journal of Musculoskeletal Neuronal Interactions (2019), 19(3), 258-265

Objectives: To provide normative values for isometric strength of 8 different muscle groups among nursing home residents and to investigate their predictive value for the decline of autonomy. Methods ... [more ▼]

Objectives: To provide normative values for isometric strength of 8 different muscle groups among nursing home residents and to investigate their predictive value for the decline of autonomy. Methods: This is an analysis of the 1-year follow-up of the SENIOR cohort. At baseline, isometric muscle strength of residents has been assessed for 8 muscle groups using the MicroFET2. The cut-off threshold for low relative isometric muscle strength was defined as the lower quartile. The outcome was the 1-year loss of autonomy (i.e. a decrease of ≥1 point on the ADL scale between baseline and 12-month follow-up). Logistic regressions were carried out to assess the predictive value of isometric muscle strength for the loss of autonomy. Results: 204 subjects (83.2±8.99 years, 72.5% women) were included. Threshold values of isometric strength were: knee flexors=0.94, knee extensors=1.07, ankle flexors=0.77, ankle extensors=0.88, hip abductors=0.78, hip extensors=0.79, elbow flexors=0.99 and elbow extensors= 0.71 N/kg. After adjustment for age and sex, the cut-off values for knee extensors (p=0.04) and for ankle extensors (p=0.03) were significantly predictive of loss of autonomy. Conclusions: The normative values for knee extensors and ankle extensors are independent predictors for loss of autonomy. © 2019, International Society of Musculoskeletal and Neuronal Interactions. All rights reserved. [less ▲]

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See detailEnergy expenditure of nursing home residents and participation in exercise classes: an analysis of the SENIOR cohort
Charles, Alexia ULiege; Buckinx, Fanny ULiege; Mouton, Alexandre ULiege et al

in Journal of the American Medical Directors Association (2019), 20(9), 1183-1184

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See detailEuropean postgraduate curriculum in geriatric medicine developed using an international modified Delphi technique
Roller-Wirnsberger, R.; Masud, T.; Vassallo, M. et al

in Age and Ageing (2019), 48(2), 291-299

Background the European Union of Medical Specialists (UEMS-GMS) recommendations for training in Geriatric Medicine were published in 1993. The practice of Geriatric Medicine has developed considerably ... [more ▼]

Background the European Union of Medical Specialists (UEMS-GMS) recommendations for training in Geriatric Medicine were published in 1993. The practice of Geriatric Medicine has developed considerably since then and it has therefore become necessary to update these recommendations. Methods under the auspices of the UEMS-GMS, the European Geriatric Medicine Society (EuGMS) and the European Academy of Medicine of Ageing (EAMA), a group of experts, representing all member states of the respective bodies developed a new framework for education and training of specialists in Geriatric Medicine using a modified Delphi technique. Thirty-two expert panel members from 30 different countries participated in the process comprising three Delphi rounds for consensus. The process was led by five facilitators. Results the final recommendations include four different domains: 'General Considerations' on the structure and aim of the syllabus as well as quality indicators for training (6 sub-items), 'Knowledge in patient care' (36 sub-items), 'Additional Skills and Attitude required for a Geriatrician' (9 sub-items) and a domain on 'Assessment of postgraduate education: which items are important for the transnational comparison process' (1 item). Conclusion the current publication describes the development of the new recommendations endorsed by UEMS-GMS, EuGMS and EAMA as minimum training requirements to become a geriatrician at specialist level in EU member states. © The Author(s) (2019). Published by Oxford University Press on behalf of the British Geriatrics Society. [less ▲]

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See detailEWGSOP2 versus EWGSOP1: impact of the prevalence of sarcopenia and its major health consequences.
Locquet, Médéa ULiege; Beaudart, Charlotte ULiege; Petermans, Jean ULiege et al

in Journal of the American Medical Directors Association (2019), 20(3), 384-385

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See detailApports de la cohorte liégeoise SENIOR dans l’étude de la fragilité en maison de repos.
Buckinx, Fanny ULiege; Charles, Alexia ULiege; Reginster, Jean-Yves ULiege et al

in Revue Médicale de Liège (2019), 74(4), 212-217

Au cours des deux dernières décennies, la documentation traitant de la fragilité s’est faite de plus en plus abondante. Toutefois, il n’existe toujours pas de définition opérationnelle et de critères ... [more ▼]

Au cours des deux dernières décennies, la documentation traitant de la fragilité s’est faite de plus en plus abondante. Toutefois, il n’existe toujours pas de définition opérationnelle et de critères universellement reconnus pour décrire la fragilité. Les critères cliniques de fragilité doivent être prédictifs du risque de déclin fonctionnel et d’événements péjoratifs de santé. Dans cette optique, identifier précocement les sujets fragiles permet d’agir sur les facteurs de risque et d’éviter les évolutions défavorables. La cohorte SENIOR, une étude longitudinale de personnes âgées résidant en maison de repos initiée en 2013, a pour objectif de contribuer à la compréhension des facteurs de risque, des conséquences et de la trajectoire de la fragilité. Elle a aussi pour but d’apporter des pistes de prise en charge. Cette cohorte suscite beaucoup d’intérêt dans le monde de la recherche scientifique. En effet, grâce aux nombreuses données démographiques, cliniques et anamnestiques récoltées annuellement, elle permet d’apporter des éléments de réponses aux problématiques liées à la fragilité des personnes âgées. [less ▲]

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See detailAssessment of the energy expenditure of Belgian nursing home residents using indirect calorimetry
Buckinx, Fanny ULiege; Paquot, Nicolas ULiege; FADEUR, Marjorie ULiege et al

in Nutrition (2019), 57

Objectives: The aim of this study was to assess the energy expenditure of Belgian nursing home residents using indirect calorimetry and compare the energy expenditure with energy intake. Methods: Indirect ... [more ▼]

Objectives: The aim of this study was to assess the energy expenditure of Belgian nursing home residents using indirect calorimetry and compare the energy expenditure with energy intake. Methods: Indirect calorimetry was performed in nursing home residents to estimate their basal metabolism. The basal metabolism was multiplied by a physical activity level coefficient and energy expenditure that was related to thermogenesis (i.e., 10% of the total amount of energy ingested over 24 h) was added. In this way, we obtained the total energy expenditure of each nursing home resident. The nutritional intake of each resident was calculated using the precise food-weighing method over a 3-d period. The difference between energy expenditure and consumption was calculated for each patient and the mean of the difference in the population was calculated. These quantitative variables were compared by means of analysis of variance. Results: A total of 25 subjects were included in this study (88.1 ± 5.8 y; 84% women). The estimated mean basal metabolism was 1087.2 ± 163.2 kcal. The physical activity level was 1.29 ± 0.1 on average and the energy expenditure due to thermogenesis was 163.1 ± 28.9 kcal. Thus, the mean daily energy expenditure was 1575.2 ± 210.6 kcal, which was within the range of the actual calculated energy intake of the residents (1631.5 ± 289.3 kcal; P = 0.33). Conclusions: The estimated energy intake of Belgian nursing home residents seems appropriate for their energy expenditure. © 2018 Elsevier Ltd [less ▲]

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