References of "Pestieau, Aude"
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See detailIn vitro biphasic dissolution tests and their suitability for establishing in vitro-in vivo correlations: A historical review
Pestieau, Aude ULiege; Evrard, Brigitte ULiege

in European Journal of Pharmaceutical Sciences (2017), 102

For many decades, one of the most critical issues in the pharmaceutical industry has been the poor solubility of some drugs. Indeed, a prerequisite for drug absorption is the presence of dissolved drug at ... [more ▼]

For many decades, one of the most critical issues in the pharmaceutical industry has been the poor solubility of some drugs. Indeed, a prerequisite for drug absorption is the presence of dissolved drug at the absorption site and this can be challenging for compounds with low aqueous solubility such as BCS class II (low solubility, high permeability) and IV (low solubility, low permeability) compounds. If the development of oral delivery formulations of these compounds is frequently challenging to formulation scientists in the pharmaceutical industry, the in vitro evaluation of these new formulations is also a great challenge. One alternative approach to overcome the problems encountered with conventional dissolution methods is the use of biphasic dissolution systems. This review provides an overview of the origin and the evolution over time of the biphasic systems and the growing interest among scientists regarding their suitability for establishing in vitro-in vivo correlations. The evolution of these systems and their applications from the 1960s to the present day, such as in system variants and improvements, analysis of complex formulations, discriminatory power, bio-relevance, precipitation and supersaturation visualization, etc. will be discussed. [less ▲]

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See detailEvaluation of different in vitro dissolution tests based on level A in vitro–in vivo correlations for fenofibrate self-emulsifying lipid-based formulations
Pestieau, Aude ULiege; Lebrun, Sonia; Cahay, Bernard et al

in European Journal of Pharmaceutics and Biopharmaceutics (2017), 112

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See detailInvestigation of a suitable in vitro dissolution test for itraconazole-based solid dispersions
Thiry, Justine ULiege; Broze, Guy ULiege; Pestieau, Aude ULiege et al

in European Journal of Pharmaceutical Sciences (2016)

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See detailSelection of a discriminant and biorelevant in vitro dissolution test for the development of fenofibrate self-emulsifying lipid-based formulations
Pestieau, Aude ULiege; Krier, Fabrice; Brouwers, Adeline et al

in European Journal of Pharmaceutical Sciences (2016)

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See detailIn vitro and in vivo evaluation of an optimized fenofibrate lipid based solid dispersion produced by a PGSS process
Pestieau, Aude ULiege; Lebrun, Sonia; Cahay, Bernard et al

Conference (2015, October 28)

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See detailIn vitro and in vivo evaluation of an optimized fenofibrate lipid based solid dispersion produced by a PGSS process
Pestieau, Aude ULiege; Lebrun, Sonia; Cahay, Bernard et al

Poster (2015, October 28)

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See detailHow to choose a suitable dissolution test for BCS II drugs?
Thiry, Justine ULiege; Pestieau, Aude ULiege; Krier, Fabrice ULiege et al

Conference (2015, May)

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See detailTowards a real time release approach for manufacturing tablets using NIR spectroscopy
Pestieau, Aude ULiege; Krier, Fabrice ULiege; Thoorens, Grégory et al

Poster (2014, June)

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See detailTowards a real time release approach for manufacturing tablets using NIR spectroscopy
Pestieau, Aude ULiege; Krier, Fabrice ULiege; Thoorens, Grégory et al

in Journal of Pharmaceutical and Biomedical Analysis (2014), 98

Detailed reference viewed: 74 (27 ULiège)